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Cardiovascular Disease - Cardiac Intermediate Filaments

Date Posted:
5/23/2018

Heart and Vascular Institute

MD

A post-doctoral fellowship position is AVAILABLE IMMEDIATELY at the Center for Research on Cardiac
Intermediate   Filaments   (CRCIF),   within   the   Johns   Hopkins   School   of   Medicine   
Institute   of Cardioscience:

http://www.hopkinsmedicine.org/heart_vascular_institute/research/by_laboratory/

The position is funded through a T32 training grant and therefore eligibility is limited to
green-card holders and citizens of the United States.

The general theme of research is centered on the interaction between cardiac intermediate filaments
(IFs) and mitochondria, in the setting of cardiovascular disease – the largest cause of
hospitalization and death in the U.S.

We recently published that desmin aggregates in the heart may act as amyloid aggregate observed in
Alzheimer’s and Parkinson’s diseases:

https://www.hopkinsmedicine.org/news/media/releases/heart_failure_the_alzheimers_disease_of_th
e_heart

The ideal candidate must be highly organized, proficient in English and interested in pursuing a
career in cardiovascular and muscle disease. A background in IFs biology is preferred and so is
technical competence in cell and molecular biology and protein biochemistry.

The successful candidate will be will be trained in protein biochemistry and proteomics as well as
mitochondrial biology. The project will span from basic research to clinical applications.

Johns Hopkins University is a competitive institution that provides for an exciting research
environment. The CRCIF is part of the Institute of Cardioscience, which along with the medical and
undergraduate campuses gives us access to a very broad set of expertise and many learning
opportunities.

Interested candidates should email an updated CV and the contacts of three references to Giulio
Agnetti at gagnett1@jhmi.edu.


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Kegan Lab – Vascular cell biology and lung physiology

Date Posted:
5/1/2018

Anesthesiology and Critical Care Medicine

MD

A postdoctoral position is available at the Johns Hopkins University School of Medicine, Department of Anesthesiology and Critical Care Medicine in the laboratory of Dr. Kazuyo Kegan, Ph.D. The overall focus of the Kegan lab is to understand the mechanisms, regulation, and functional outcomes of immune responses in the pulmonary vasculature during the development of pulmonary hypertension. To elucidate these mechanisms, fellows will use in vivo animal models, genetically modified animals, in vitro cell biology, immunohistochemistry, and genetic and biochemical approaches.

A successful candidate will use basic science approaches to address clinically relevant issues within a multidisciplinary team that includes clinician scientists and biomedical engineering groups.

Candidates should have a PhD degree (or equivalent) with a background in physiology, cell and molecular biology, biomedical science, or pharmacology. Individuals with experience in vascular/macrophage biology, immunology, or stem cell research will be given preference.

Please submit an application including a cover letter and CV that describes your research interests and accomplishments, and information for references (as a single PDF file) to Dr. Kegan at kkegan1@jhmi.edu .

 


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Han Lab - Computational Genetics

Date Posted:
4/23/2018

Psychiatry and Behavioral Sciences

MD

A postdoc position is now available to work with Dr. Shizhong Han, Associate Professor, in the Department of Psychiatry and Behavioral Sciences at Johns Hopkins.

Research in Dr. Han’s lab has been focused on investigating the genetic basis of psychiatric disorders, especially alcoholism and substance abuse. Another research focus is on developing statistical genetic approaches and computational tools that will facilitate the effort to identify disease susceptibility genes more broadly.

The candidate is expected to work with Dr. Han to develop and apply machine learning and network-based approaches to risk gene identification, disease risk prediction, and drug discovery for psychiatric disorders. Candidates with a doctoral degree in human genetics, bioinformatics, or other fields with strong quantitative skills (e.g., biostatistics, statistics, or computer science) will be considered.

Strong programing skills in Perl/Python and R are essential. Experiences with large-scale genetic or genomic datasets are necessary. Experiences with network-based approach or machine learning are a plus. The candidates need to be highly motivated, excellent in academic writing, and able to work well in a collaborative environment.

The successful candidate will receive intensive training on projects tailored to his/her research interests and experiences. The successful candidate will be encouraged to present research work in national and international meetings, and be supported for professional development.

Interested applicants should send curriculum vitae, statement of research interests, and contact information for three references to Shizhong Han at shan67@jhmi.edu

 


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Trock Lab - Prostate cancer biomarker research

Date Posted:
3/27/2018

Urology

MD

A two-year Postdoctoral position is available at the Johns Hopkins University School of Medicine Department of Urology in the laboratory of Dr. Bruce Trock, Ph.D.  The Department of Urology is one of the world’s premier prostate cancer academic research organizations.

The candidate will conduct epidemiologic/translational research on biomarkers and other prognostic factors to develop clinical-genomic models that predict aggressive prostate cancer and clinical outcomes.

 The successful candidate will have:

  1. Defended a PhD in epidemiology, biostatistics, or related field by May 31, 2018.
  2. A proven record of scholarship in cancer research
  3. Excellent biostatistical data analysis skills using SAS, STATA, or R software.
  4. Excellent organizational and communications skills.

The position will involve collaboration with epidemiologists, biostatisticians, physicians, basic scientists, and will integrate clinical, epidemiologic, biomarker, and outcomes data.  The research will provide ample opportunity for publication  Applicants should be capable of independent experimental design and manuscript preparation.  An ideal candidate has an open mind, and is keen to learn, work and train in a highly collaborative multidisciplinary environment.

 Please submit an application including a cover letter and CV that describes your research interests and accomplishments to Dr. Trock at btrock@jhmi.edu .


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Critical Social Analysis of Health and Disease

Date Posted:
2/27/2018

Center for Medical Humanities and Social Medicine

MD

Postdoctoral Fellowship,

Center for Medical Humanities and Social Medicine

Johns Hopkins University

The Center for Medical Humanities and Social Medicine, Johns Hopkins University, seeks applicants for a two-year postdoctoral fellowship.  The Center is an interdisciplinary teaching and research unit that bridges the humanities, social sciences, and health sciences across the campuses of Johns Hopkins University to foster innovative, interdisciplinary scholarship and to train undergraduates, graduate students, and health professionals with skills to apply critical social analysis to the understanding of health and disease.

The fellow will work closely with faculty and trainees across multiple campuses of the University to foster the intellectual life of the Center, with protected time to pursue his or her research and writing.

The successful candidate will have:

  1. Defended a PhD in anthropology, history, sociology, philosophy, literature, or related field by May 31, 2018.
  2. A proven record of interdisciplinary scholarship and teaching in the humanities and/or social sciences of health and medicine
  3. Previous Interactions with health science as well as arts and science campuses
  4. A strong research profile
  5. Excellent organizational skills

Duties will include organizing Center events; working with the Director and faculty to develop new programs; liaising with faculty and trainees across multiple campuses of Johns Hopkins University; and developing online content for the Center’s online and social media presence. The fellow will pursue a sustained program of research and writing, mentored by Center faculty, and make satisfactory progress towards publication goals.

Closing date for applications: March 21, 2018. Skype interviews will be conducted in early April. The term of appointment is two years, beginning July 1, 2018. Salary: $47,484 plus benefits.

Please send: cover letter; CV; statement of interest in medical humanities and/or social medicine; dissertation chapter or other writing sample; and arrange to have three letters of recommendation sent directly to our program coordinator, Marian Robbins at myrobbins@jhmi.edu.

Johns Hopkins University is an AA/EOE and actively encourages applications from minority and women scholars. NOTE: The successful candidate for this position will be subject to a routine background check.


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