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Medical Writer

Date Posted:
5/29/2017

Cactus Communications

MD

The medical communications team at CACTUS works with the Top 10 global pharmaceutical, biotech and device companies across a wide range of communications needs including writing, graphics, animation, and strategy for their regulatory and publications teams. We act as trusted advisors by constantly and consistently delivering excellence that goes way beyond just our technical expertise. We work as an extension of our client teams and provide them with flexible and innovative solutions that allow them to manage their budget wisely and do more with less while maintaining high levels of quality and data integrity.

Please see the link to know more about us https://www.youtube.com/watch?v=lBUNR8GnkMU

The Medical Writing team at CACTUS specializes in providing rigorous medical and scientific writing services for pharmaceutical corporations, clinical research organizations, and researchers worldwide. We are looking for experienced researchers to join our team of world-class medical writers and work in a dynamic, fast-paced global environment.

• The opportunity:

If you are looking for challenging and rewarding work which combines your understanding of medical science and aptitude for writing into one unique job, the Medical Writer role is for you. This is an opportunity to grow your career and make a greater impact on the lives around you.

Roles & Responsibilities:

• You will use scientific expertise to develop high-quality, publication-ready scientific documents (manuscripts, posters, abstracts, slide kits, short communications, etc.) according to client needs under the expert guidance of the Scientific Team Lead
• You will act as a document specialist, provide intellectual input across document types, and contribute to making cutting-edge research accessible to specific audiences as appropriate, by maintaining current awareness of developments across therapeutic areas or disciplines.
• You will work with international pharmaceutical clients and liaise with internal and external stakeholders, including authors and key opinion leaders on critical therapeutic area issues
• Effectively and proactively communicate with team members, authors/faculty, clients, and vendors
• Attend workshops/seminars/Trainings to hone your skills and contribute to organizational objectives.

Note: Flexible work arrangements are available.

So how do we know that’s you? You have the personality and the experience:

• PhD/MD (Pharmacology) or PhD (Life Sciences) or MBBS/MD (Internal Medicine) with a good understanding of clinical research and medical communication
• Publication experience, preferably as first author on papers published in medical journals
• Clear, concise, scientific style of writing, with a high level of attention to detail and superior English-language skills
• Basic knowledge of biostatistics
• Literature reviewing and evaluation capabilities
• Ability to multi-task and work under tight timelines

• What’s in it for you?

Global exposure: We work with the top 10 Pharmaceutical companies across the globe. So you can be assured that you get the best experience in terms of the profile you handle.

Culture & Team: We never stop recruiting the best people in the market because without an amazing team nothing is possible. People at CACTUS are awesome to work with, driven, smart and know how to get things done like nobody else.

Learn & Grow: Our goal is to keep you as long possible and help you build a career with us. We do this by creating an environment where you will grow both personally and professionally.

Satisfaction & Recognition: With some of the biggest names across the globe as existing clients, doors will open and conversations will flow. You will see the results of your efforts translate into maximum impact. With a competitive salary and our recognition programmes, you will be rewarded for your success.

• Why Join CACTUS?

Cactus Communications is a leading provider of communication solutions, including academic and scientific editing, medical communications, publication support services, English-language workshops, transcription, and translation. Our company mission is to enable growth through effective communication.

CACTUS offers services to two key client segments worldwide: Academia (researchers, scholarly journals and publishers, universities, and academic societies) and Pharmaceutical and Device companies.

To learn more, please visit:
www.cactusglobal.com

Awards:

• CACTUS is proud to finish among the top 20 companies offering remote jobs for two consecutive years! Flexob
• CACTUS is among the top 20 great places to work for three consecutive years. GPTW

Application process:

To apply, e-mail your updated CV along with a cover letter to behappy@cactusglobal.com or call Komal Sharma on +912267148888


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Associate Editor

Date Posted:
5/29/2017

Nature

NY

Nature Research is a flagship portfolio of journals, products and services including Nature and the Nature-branded journals, dedicated to serving the scientific community.

Job title:
Associate or Senior Editor, Major new Nature Research open access journal in Biology

Line Manager:
Chief Editor

Location:
New York or London

Purpose of the role:
Responsible for handling primary manuscripts in a relevant subject specific area of the life sciences and managing the peer review process. Liaise with the external editorial board. Maintain the visibility, scientific standing and quality of the journal.

Key tasks:
Help with the selection of manuscripts for publication in the journal.
Ensure quality and speed of decisions; and the right mix of tact and firmness in letters to authors.
Guide and assist external editors with the tasks listed above.
Ensure that accepted manuscripts are transferred to Production in an appropriate, complete state.
Suggest and write content for the journal, website or other social media.
Attend conferences and meetings and visit research institutions.
Devise and supply editorial content for special projects, such as supplements.
Participate in the delivery of Masterclasses to support business requirements.
Such other tasks as the company may assign from time to time.
Key relationships:
Work with other members of the editorial and administrative staff.
Interact with the Chief Editor, Publisher and Publishing Director who will set overall policies and procedures for the journal
Interact with the Production team to ensure the smooth processing of manuscripts and other material, according to production deadlines.
Advise Advertising and Marketing departments as required, answering questions raised and offering suggestions/leads wherever possible.
Establish, enhance and confirm the reputation of the journal and Springer Nature in the scientific community by fostering good relationships with individual researchers.

Qualifications:
PhD in a relevant discipline. Post-doctoral experience would be advantageous but is not essential.

Skills/knowledge:
Basic computer skills; experience of eJP would be advantageous

Experience:
Editorial experience is beneficial but not required. For the Senior Editor position, at least 2 years of editorial experience on a peer-reviewed publication.
A thorough understanding of the scientific research community and its needs.
Positive ability to develop long-term professional relationships with key members of the scientific community.
Sound knowledge and interest in science in general.
Strong interpersonal and influential communication skills, with effective presentation skills.
Highly self-motivated, resourceful and achievement oriented.
A creative approach to strategic planning and problem-solving.
Active, supportive team player.
Adaptability and flexibility – willing and able to travel to Europe, Asia and within the US.

We offer a comprehensive benefits package that includes:

– Medical, Dental and Vision
– Life and AD&D
– 401(k)
– Flexible Spending Accounts
– Transit Accounts
– Tuition Assistance
– Summer Hours

Springer Nature is an Equal Opportunity Employer that complies with the laws and regulations set forth in the following EEO Is The Law Poster:
http://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf.

Visit the Springer Nature Editorial and Publishing website at www.springernature.com/editorial-and-publishing-jobs for more information about our Research E&P career opportunities.

Springer Nature is a leading global research, educational and professional publisher, home to an array of respected and trusted brands providing quality content through a range of innovative products and services.

Springer Nature is the world’s largest academic book publisher, publisher of the world’s highest impact journals and a pioneer in the field of open research. The company numbers almost 13,000 staff in over 50 countries and has a turnover of approximately EUR 1.5 billion. Springer Nature was formed in 2015 through the merger of Nature Publishing Group, Palgrave Macmillan, Macmillan Education and Springer Science+Business Media.

Please apply for this position online:
https://career012.successfactors.eu/sfcareer/jobreqcareer?jobId=19629&company=C0001215517P&username=


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Scientist PreCLINICAL

Date Posted:
5/27/2017

Seattle Genetics

WA

Summary:

The Preclinical Research group of Seattle Genetics is seeking a highly motivated scientist with strong translational research expertise.  Seattle Genetics is an established leader in the development of tumor-directed antibody-drug conjugates (ADCs) and is expanding into therapeutic approaches involving immune modulation. These include co-administration of ADCs with approved immuno-oncology agents (e.g. checkpoint inhibitors), development of novel immuno-oncology agents, and evaluation of existing ADCs in autoimmune and inflammatory disorders. The scientist will perform cross-functional research to understand the mechanisms of disease biology and drug actions, as well as contribute to the advancement of the company’s drug development pipeline.

 

Responsibilities:

  • Design, perform, and document cell biology experiments to validate targets for antibody-based therapeutics

  • Identify new cancer drug targets and advance antibody-based drug candidates from inception to clinical development

  • Develop novel assays and experiment systems to mimic the disease biology and facilitate translation between research settings and clinical trials

  • Represent preclinical research on various project teams. Contribute to study design and data interpretation

  • Articulate and present scientific work at cross-functional group and national meetings

 

Qualifications:

  • Ph.D. in Cancer Biology, Cancer Genetics, Immunology, Genomics, Cell Biology or related fields in cancer research. Candidates with knowledge in acute myeloid leukemia are encouraged to apply

  • Ideal candidates will have 2+ years successful post-doctoral research experience, as demonstrated by a strong publication record

  • Technical expertise in multicolor flow cytometry, cell biology assays and tissue culture techniques ( e.g., engineering cell lines), biochemical methods to investigate signal transduction pathway ( e.g., western blotting and microscopy),  and rodent cancer models

  • Familiarity with cancer genome databases and large scale data analysis and mining. Experience with RNA-sequencing is a plus

  • Candidates must have good interpersonal skills to work collaboratively in a team environment and excellent oral and written communication skills.

  • Creative, independent, well organized, collaborative, and solution-oriented 

 

Seattle Genetics is an equal opportunity employer. All qualified applications will receive consideration for employment without regard to race, color, religion, sex, national origin, protected veteran status, or disability status.


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Scientist Potency Assays

Date Posted:
5/27/2017

Seattle Genetics

WA

This position will focus on the development of biological assays to support the development and characterization of Seattle Genetics' (SGEN) antibodies and antibody-drug conjugates (ADCs). The successful candidate will work closely with various functional areas within Process Sciences and with Quality Control. The successful candidate will develop, qualify and implement potency assays to support process development activities, drug product release and regulatory filings. 


Responsibilities:

  • Develop, qualify and implement robust potency assays (cytotoxicity, binding ELISAs, effector function and other assays) to support early and late phase product and process development
  • Transfer potency assays from to QC GMP group
  • Generate reporter cell lines that can be used for the assessment of biological activity of pipeline molecules
  • Represent the group as a technical lead on CMC and other cross-functional teams, develop and lead group initiatives
  • Write technical reports and CMC documents to support regulatory filings
  • Supervise and mentor research associate(s)


Qualifications:

  • Ph.D. in Immunology, Molecular Biology, Cancer Biology, Microbiology or related discipline
  • 1-2 years’ industrial experience desired
  • Demonstrated technical expertise in cell-based assays, ELISAs, Octet, FACS, tissue culture and molecular biology techniques, including vector design and construction, transfection, selection, single cell cloning, cell banking and cell line genetic characterization
  • Experience in the use of live cell imaging systems is desired
  • Candidate must be high motivated and be able to work in a fast-paced, matrixed environment
  • Strong interpersonal skills and the ability to work a multi-disciplinary team environment
  • Excellent oral and written communication skills
  • Experience with regulatory submissions preferred
  • Creative, independent, well-organized and solution-oriented
  • Supervisory experience preferred

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Scientist I

Date Posted:
5/27/2017

Nanostring

WA

NanoString Technologies is seeking an experienced Scientist to join our Product Development team.  In this position, S/he will work with a cross functional team to develop new molecular diagnostic and companion diagnostic products with a particular focus in Oncology.  S/he will be responsible for developing and validating novel diagnostic gene signature assays on the nCounter Dx Analysis System.  S/he will be required to design experiments to test gene signature assays and analyze genomics/gene expression data, write test plans and reports, and work cross functionally to transfer reagents and assay testing procedures to a production or clinical environment.  S/he also will be required to use molecular biology techniques to develop new molecular diagnostic reagents.  S/he will be expected to provide technical leadership and communicate results to the cross functional team, as well as contribute as an individual researcher. 

Essential Functions:

  • Use molecular biology techniques to develop and validate new molecular diagnostic reagents for use in diagnostic gene signature assays
  • Design experiments to test the sensitivity, specificity, and reproducibility of new diagnostic gene signature assays
  • Analyze genomics data  
  • Develop assay procedures required for new gene signature assays
  • Work as part of cross functional team to deliver new diagnostic products on tight timelines

Requirements (Education, Experience, Specific Skills):

  • Ph.D. in molecular biology, biochemistry, bioengineering, or related field with a minimum of two years of relevant post-doctoral or work experience, or an M.S. with a minimum of 6 years of relevant work experience.
  • Detailed understanding of state-of-the-art molecular biology techniques
  • Extensive knowledge of nucleic acid manipulation and characterization techniques (i.e., NGS, Q-PCR or hybridization assays)
  • Preferences for experience working in an ISO certified or QSR certified facility and experience developing products for the life sciences and/or molecular diagnostics industries
  • Strong analytical and organizational skills exemplified by clear oral presentations and written documentation
  • Familiarity with software tools used for the analysis of gene expression data
  • Familiarity with a statistical analysis package is strongly preferred but not required
 

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Scientist i Genetic Biomarker Assay Development

Date Posted:
5/27/2017

JBS

PA

An exciting new position is now open for someone seeking to apply their skills in SOP development of genetic biomarkers for the detection of oncology targets. The position will involve development and validation of SOPs for cell-free tumor DNA-based assays for genetic markers. The individual must excel in a team-based environment composed of molecular biologists, biochemists, bioinformaticians, and geneticists.

Major Responsibilities:

  • Develop SOPs for genetic assays to support commercialization of diagnostic tests, which will include: Defining standard calibration curves, limit of detection (LOD), range of linearity, reproducibility, specimen comparison, stability, and producing standard GLP reagents
  • Ensure assay development is consistent with FDA regulations
  • Provide expertise on scientific projects and evaluate clinical applicability
  • Possess excellent bench skills and careful experimental planning
  • Capable of troubleshooting and providing alternative solutions
  • Support a culture of continuous process improvement
  • Create technical documentation including protocols, SOPs, and technical reports
  • Work closely with and collaborate effectively with project lead and team to support project planning, scheduling of tasks, and communicating project status to management


Required Experience:

  • B.S. or M.S. with 2+ years experience, or Ph.D. preferred
  • Experience with SOP development, qPCR assay development, and/or genetic diagnostic testing
  • Extensive knowledge and experience with common molecular biology techniques Hands-on experience with PCR, qPCR, and nucleic acid techniques is preferred
  • Excellent communication skills; able to interpret and troubleshoot complex scientific ideas
  • Proven ability to solve complex scientific problems using critical analytical approaches
  • Background in oncology a plus
  • Detail oriented, excellent organization skills, and efficient time management
  • Ambitious and willing to work on multiple projects

Interested applicants should send CV, contacts for personal references, and statement of interest to JBS Science, Inc at info@jbs-science.com.


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Proteomics Research Scientist

Date Posted:
5/27/2017

Thermo Fisher

IL

We are seeking a protein mass spectrometrist (MS) for our immunoassay research and development group with strong teamwork and problem solving skills.  This individual will lead the validation of new reagents and workflows for antibody validation using immune-based protein enrichment and MS detection.  The successful candidate should have experience with cell culture, immunoprecipitation, protein and peptide sample preparation and automation, and nanoLC-MS/MS analysis.  Besides strong sample preparation, computer, and general laboratory skills, this position requires an ability to work in a highly collaborative, fast-paced environment that integrates reagents, instruments, and software for protein characterization and quantitation.  The individual will work with business development, strategic marketing specialists, and R&D colleagues from the Thermo Fisher Scientific immunoassay and protein mass spectrometry reagents groups. Strong verbal and written communication and leadership skills are essential. Apply online at: http://jobs.thermofisher.com/ShowJob/Id/8551/Scientist-III-Mass-Spec-Reagents/

Requirements
  • M.S. or Ph.D. degree in Analytical Chemistry, Biochemistry, or related discipline. 
  • Excellent knowledge and practical experience with cell culture and lysis, proteomics sample preparation techniques, automation, immunocapture, peptide and protein identification with Thermo Scientific Orbitrap-based MS instrumentation, and data analysis with Proteome Discoverer and Maxquant/Perseus software
  • Strong oral & written communications skills and experience working in a matrix organization
  • Demonstrated teamwork and troubleshooting skills
  • Experience in product development and/or project management is highly desirable.
 

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Associate biotech investment

Date Posted:
5/27/2017

EcoR1

CA

Join a small, entrepreneurial team in a relatively new, growing fund with a start-up culture.
EcoR1 Capital LLC is a value-oriented biotechnology focused investment fund. Based in San Francisco, EcoR1 evaluates and selects extraordinary biotechnology companies that are pursuing the highest quality science and demonstrate strong business fundamentals. EcoR1 invests in both private and public companies across therapeutic categories. We are seeking an associate for the investment team. The role involves everything from sourcing opportunities to doing primary diligence on investments through reading scientific papers, attending medical and investor conferences, meeting with management teams and financial modeling.

But enough about us; let's talk about you.
You:
• have a propensity for science and a general curiosity about the world
• have 1-4 years of experience at a management consulting firm, investment bank, law firm or have a background in a primary research based profession like investigative journalism
• are a contrarian who does not take anything at face value
• are detail-oriented, but are efficient with your time
• are OK answering the phone, making coffee and investigating a potential cure for cancer all in the same day
• are interested in committing to a profession in which the learning curve will take years to climb
• have a perfect combination of confidence and humility
• can walk up to a stranger, whether a movie star or a noble laureate and strike up a conversation
• are an amazing listener
• squeak 32 hours out of every 24 hour day
• think standing at a desk is better than sitting at one
• are HUNGRY
• will know more about me and this Fund when you come in for an interview than I do

Timing: We are looking for someone ASAP. But we are willing to wait for the right fit.

If those points sounds like they describe you, please

NOTE THE FOLLOWING ADVICE:
• If you have more than 4 years of work experience, you will grow out of this role too quickly and this is not the best fit for you

Applicants should include their resumes and answers to the following five questions if they wish to be considered for the role.

A) Please describe why you think researching potential opportunities in the life science space is a good way to spend 12 hours a day.
B) What are you passionate about?
C) What makes you a contrarian?
D) Why are you a good match for the "You" we describe above?
E) What is your favorite joke?


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Associate

Date Posted:
5/27/2017

Bridge Bio

CA

About BridgeBio
BridgeBio is a precision medicine company located in Palo Alto, CA, that focuses on developing therapies in the pediatric genetic disease and targeted oncology spaces. The company primarily invests in or builds pure play single-asset biotech startups. In aggregate, BridgeBio seeks to create a broad, diversified portfolio of drug development efforts which are uncorrelated from a risk standpoint. BridgeBio has 9 portfolio companies to date ranging from pre-clinical to phase 2 clinical.

With its deep bench of expertise in science, medicine and drug development, BridgeBio’s asset acquisition team and investment committee rigorously evaluate and select therapeutic ideas to support. BridgeBio team members employ their significant operational and company-building knowhow to accelerate the pace of drug discovery. The company is led by veterans from Third Rock Ventures, and is backed by a bulge bracket private equity firm and a large healthcare hedge fund.

The Opportunity
BridgeBio is seeking to expand its core diligence and operations team. Over the coming 12 months the company will focus on two goals: building value in its existing assets, and investing in or acquiring 3-5 promising new therapeutic assets. BridgeBio seeks an individual who will assist in the scientific, clinical, and commercial due diligence for new assets. She or he will also work in an operational role to help build new portfolio companies from the ground up.

The Role
The Associate will be a critically important player and will work directly with the asset acquisition team in building BridgeBio. Specifically, the workstreams that the Associate would be responsible for are:

  • Interface with leading academics and biopharma companies to source investment opportunities in the genetic disease and precision oncology spaces
  • Monitor the literature for new therapeutic opportunities relevant to the BridgeBio thesis
  • Assess pre-clinical and clinical data packages and associated business plans
  • Build and evaluate a business case for each investment in consultation with internal and external scientific and clinical experts
  • Lead internal meetings to review pipeline assets
  • Contribute to operations and company building at portfolio companies
  • Shape the culture of BridgeBio as a member of a small and growing team

Qualifications
The successful candidate should possess proven scientific and communication skills and be able to establish an independent and focused investment strategy:

  • PhD highly preferred, ideally with expertise in genetic disease or translational oncology
  • Confidence evaluating therapeutic approaches across a wide range of disease areas
  • Exceptional communication skills, with the ability to express ideas cogently in writing
  • A self-starter who can take responsibility for diligence projects with little oversight required
  • A passion for helping patients
 

 


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Investment Professional

Date Posted:
5/27/2017

MVM Life Science Partners

NY

MVM Life Science Partners LLP (MVM) is a healthcare focused venture capital/growth equity firm founded in 1997. MVM pursues global opportunities through its offices in Boston and London and invests broadly across the healthcare sector, including biotechnology, specialty pharmaceuticals, medical technology and diagnostics. Since the closing of its $230 million fourth fund, the partners have identified a need to add an Investment Professional to the team based in the Boston office.  Subject to first-rate performance, it is our intention that this role leads to membership into the MVM partnership.

 

Role and key responsibilities

The Investment Professional will be responsible for the following:

  • Screening and analyzing potential investment opportunities
  • Managing all parts of the deal process
  • Technical, clinical, commercial and financial diligence
  • Identifying influential businesses and building relationships with them for the future
  • Portfolio monitoring

 

Specifications

People most likely to be successful in the role would have the following backgrounds:

  • MD, life science PhD or Masters with first class academics
  • One to four years additional commercial experience, likely gained in strategy consulting, possibly in an equity research or business development role in the healthcare sector. Prior investing experience is a benefit but not required
  • Able to identify commercial drivers and assess technical risk
  • Detailed and rigorous whilst also being able to see the bigger picture and articulate the commercial drivers of a situation
  • A well balanced personality, the ability to interact positively and empathetically with others, and driven self-motivation

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Equity Analyst

Date Posted:
5/27/2017

Tang Capital

NY

Tang Capital is an investment firm specializing in the biopharmaceutical sector. We are seeking scientists looking for a fast-paced, intellectual work environment to join our Managing Director in the New York office. The position entails fundamental scientific and financial research on drugs across a wide range of diseases to support existing portfolio companies as well as to support the search for new startup ideas. Team members will have a unique opportunity to gain experience in both investment research and analysis as well as operational skills in advancing drug development programs within biotechnology companies. Please send a cover letter and resume.


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Biotech Hedge Fund Fellowship

Date Posted:
5/27/2017

Chambers Point

MA

Company Description

Chambers Point Capital, LP is a life-sciences focused hedge fund based in New York. At our core we are committed to supporting healthcare innovation by investing in passionate scientists and ambitious management teams that are on the cusp of breakthroughs in the understanding, diagnosis and treatment of unmet medical needs.

Role

We are looking for self-motivated, well-rounded candidates with a combined life science and investing background that enjoy investigating clinical trials and identifying underappreciated therapies with potential for widespread impact.

This part-time role allows for flexible hours and working locations, and can be adapted to supplement your academic focus or research interests. You can start and end at your convenience, and there is potential for a permanent role on the investment team down the road.

Responsibilities and Schedule

  • Analyze and interpret clinical data and scientific literature for drugs under development

  • Analyze a product’s chances for clinical and regulatory success, identifying potential setbacks

  • Assess disease profiles and market potential; construct bottom up financial projections

  • Part-time, work on idea-by-idea basis. Fully flexible start and ends dates

  • Work remotely, report to our New York office for occasional investment committee meetings

Qualifications

  • Current or recent grad student, MBA, PhD or post docs with advanced life science background with specific expertise in biology, biochemistry, pharmacology or biostatistics

  • Able to interpret scientific articles, clinical trial data and trial biostatics

  • Strong financial, accounting and analytical skills to build models for diseases/therapies and company specific valuation models (e.g., DCF-NPV)

  • Autonomous, entrepreneurial, intellectually curious and questioning

Our Commitment to You

Candidates will learn how the science underlying treatments interacts with trial design and business fundamentals to impact stock prices and will work closely with our Chief Scientific Officer and Chief Investment Officer to learn about identifying mispriced healthcare investment opportunities.

If our mission and approach resonates with you, please send your CV.

To learn more, visit www.chamberspoint.com 


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Scientist Immunolgy

Date Posted:
5/27/2017

Evelo

MA

Evelo Biosciences, founded by Flagship VentureLabs has established the leading therapeutics discovery and development based on the human immuno-microbiome. We are developing onco-microbials for the treatment of cancer and immuno-microbials for the treatment of autoimmune and inflammatory diseases.

We are seeking talented and dedicated Scientists, who are interested in joining a highly dynamic and intellectually challenging team. This exciting role will afford Scientists the opportunity to be intimately involved in the implementation of cutting-edge research programs in a multifunctional biology laboratory.   Successful candidates will possess expertise in immunology and/or immuno-oncology and a proven ability to multi-task within scope. 

 Primary responsibilities:

- Design and conduct in vitro immune cell-based assays for screening, discovery, and mechanistic analysis of microbial drug candidates

- Design and implement rigorous ex vivo assays to understand immunological mechanism of action 

- Develop and implement multi-parameter flow cytometry-based immune phenotyping assays, cell sorting assays, and multiplex cytokine profiling assays

- Actively participate on project teams and collaborate across interdisciplinary R&D programs

-Independently design rigorous experiments, interpret data, and communicate findings in well-articulated presentations

 

Desired capabilities, skills and experience:

 

- Candidates must have a background in immunology, immuno-oncology, drug discovery with experience in microbiome field a plus

- Proficient in flow cytometry techniques, cytokine/chemokine profiling on Luminex or similar platform

- Experience with primary mammalian cell culture, cell proliferation assays, and/or metabolic assays

- Experience with ex vivo rodent sample processing, including RNA/DNA extraction, immunophenotyping, and immunohistochemistry

- Highly motivated and results driven individual with a passion for working in a fast-paced and evolving organization

- Strong oral and written communication as well as excellent collaboration & interpersonal capabilities

- Outstanding team player with ability to work in groups as well as independently 

- Adept at problem solving

 

Education and experience requirements:

- Ph.D. in immunology or related field

- 3-5 years of relevant experience in biopharmaceutical industry strongly preferred


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Research Informatics Scientist

Date Posted:
5/26/2017

H3 Biomedicine

MA

H3 Biomedicine seeks a creative and highly motivated Research Informatics Scientist to join our research & development team located in Cambridge, MA. The ideal candidate will be an experienced drug discovery scientist with a track record of applying informatics solutions to all stages of the drug discovery process. Additionally, the successful candidate will have strong communication skills and a good understanding of drug discovery. Candidates who are enthusiastic team players and have a passion for playing a key role in the discovery and development of life-saving medicines are encouraged to apply.

Principal Duties and Responsibilities:

  • As a member of the Discovery Informatics group, develop and implement strategic data management practices.
  • Interact with scientists to identify informatics needs and implement solutions using internal tool development as well as commercially available software.
  • Support and enhance informatics systems.
  • Write and implement efficient automated data retrieval, merging, and processing algorithms.
  • Provide training and ongoing support to scientists for scientific data management systems and data analysis tools.
  • Proactively identify, propose and champion new solutions and approaches
  • Collaborate with project teams across Research to implement data analysis and visualizations that impact project team decision-making.
Requirements

Qualifications:

  • Degree in chemistry, biotechnology, computer science, or relevant field with 5+ years’ experience implementing research informatics (cheminformatics, bioinformatics, or clinical/translational informatics) solutions within the biotech/pharmaceutical industry.
  • The candidate must have working proficiency in Java, Python, and SQL.
  • Up-to-date on industry leading approaches to data manipulation, analysis, and visualization.
  • Detailed knowledge and experience working with common informatics tools such as Pipeline Pilot, Spotfire, Certara D360, etc.
  • Experience with Amazon Web Services is highly desired.

H3 Biomedicine is a leading company in cancer genomics based drug discovery, delivering on the promise of precision medicine.  H3 aims to produce novel cancer therapeutics using a Patient to Patient Strategy aiming to exploit changes in the cancer genome of patients.  Our highly integrated multidisciplinary scientific teams apply their expertise in cancer genomics, target validation, assay development, compound production and compound optimization, to advance a selected target through focused proof of concept milestones that ultimately demonstrate cancer dependency to the target in genetically defined cancer patient populations.

Interested candidates may forward a CV to h3_career@h3biomedicine.com


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Scientist I mRNA Process Dev

Date Posted:
5/26/2017

Bluebird Bio

MA

Join bluebird bio’s enthusiastic and collaborative team by contributing to the overall success of our novel gene therapy approach. bluebird bio seeks an outstanding scientist to add to the mRNA Process Development team.  The focus of this group is to assist in the seamless transition of mRNA based programs from Research to Process Development.  The candidate’s primary responsibilities will be to develop and scale-up mRNA production processes, support analytical development of mRNA, and perform internal and external technology transfers.  We seek candidates with proven ability to successfully work independently and collaboratively across functions to achieve optimized project plans, with the ultimate goal to deliver therapies that transform the lives of patients.


About the role:

Responsible for the planning and execution of mRNA production and purification development activities appropriate for GMP manufacturing.

  • Lead screening, optimization and scale-up efforts for enzymatic reactions, chromatographic separations (e.g. affinity, IEx, HIC, SEC), and filtration processes including microfiltration, depth filtration, ultrafiltration, diafiltration, and sterile filtration.
  • Support technology transfer to manufacturing by generating development reports, reviewing master batch records, and providing technical support.
  • Develop analytical methods for the evaluation of drug substance or process intermediates utilizing SEC, CGE, RP-HPLC, LC/MS, and restriction mapping.
  • Assist in qualification of robust molecular and cell-based assays for support of in-process controls and final product release testing.
  • Lead studies for process improvements and advancements.
  • Contribute to the technical review of supporting documents, reports, and change controls, including CMC sections for regulatory filings.
Requirements

About you:

  • BS with 8+ years of directly related experience, MS with 6+ years of directly related experience, or PhD with 2+ years of directly related experience. Degree emphasis in Biochemistry, Chemical Engineering, Molecular Biology, Bioengineering, Molecular Medicine, Genetics or related field preferred.
  • This position requires conducting laboratory experiments, excellent documentation review and writing skills, and the flexibility to work on multiple projects as needed.
  • In-depth understanding of purification of biologics, specifically mRNA, including process scale-up, scale-down, and tech transfer. A proven track record of purifying multiple drug modalities is strongly preferred.
  • Understanding of nucleic acid chemistry, enzymatic and chemical reactions, PCR, plasmid processing, and standard analytical techniques for macromolecules.
  • Proficient with ÄKTA systems and UNICORN control software.
  • Experience with high-throughput process development techniques and statistical design of experiments (DoE) strongly preferred.
  • Understanding of requirements for development of biologics including requirements for product comparability.
  • Experience in working with vendors.
  • Track record of completing deliverables within specified timelines.
  • Knowledge of GMP/ICH/FDA regulations strongly preferred.
  • Independently motivated, detail oriented and good problem solving ability.
  • Excellent organizational skills, sufficient to multi-task in an extremely fast-paced environment with changing priorities.
  • Willingness to embrace the principles of the bluebird bio culture: b colorful, b cooperative, and b yourself

 


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Bioinformaticist

Date Posted:
5/26/2017

Finch Therapeutics

MA

Finch Therapeutics is unlocking the therapeutic potential of the microbiome via our human-first drug discovery platform. We support clinical studies that intentionally manipulate the microbiome to investigate causality in diseases that are otherwise poorly understood, then leverage this clinical data to focus our in vitro and in vivo efforts on cocktails of microbes that have already demonstrated safety and efficacy in humans.  Using high-throughput molecular data these human and ex-vivo experiments, we identify specific strains that drive clinical phenotypes and responses to microbial therapies. Our team values transparency, integrity, humility, and collaboration, and we intend to have fun while maximizing our ability to make an impact on patients’ lives. We are searching for passionate teammates eager to support this mission.

Job Description:

As a member of our Data Science team, your mission is to develop tools and execute analyses to support development of successful microbial therapies. You will further our microbial drug development platform by mining microbial datasets, developing our machine learning platform, and working closely with both bench scientists and clinicians to test functional hypotheses about microbial community disease. 

Responsibilities will include but are not limited to:

  • Collecting, cleaning, processing, and analyzing high-throughput microbial data, human clinical data, and in vitro data
  • Creating effective graphical output to communicate results
  • Reviewing literature and presenting summaries to inform experimental design
  • Working closely with bench scientists to analyze microbial function and phenotype experiments
  • Working with clinicians to help analyze clinical trial data
  • Communicating analysis results with a variety of audiences including clinicians, bench scientists, industry executives, and academic researchers
  • Working effectively as part of a multifunctional team in support of a commercially viable therapeutics discovery platform
  • Performing statistical tests on high throughput data
Requirements


Qualifications:

  • BA or MS in computational biology, bioinformatics, or related field
  • Facility with data visualization, especially with python matplotlib
  • Ability to work independently
  • Ability to adapt to a fast paced startup environment and perform analyses in a time sensitive fashion
  • Strong organizational and communications skills
  • Passion, humility, and excitement for doing whatever it takes to drive research forward

Additional Desired Skills & Experience (not required)

  • Previous experience developing database architecture or reference sequence datasets
  • Familiarity with cloud computing, in particular AWS EC2, CFN
  • Experience with bioinformatics software and platforms (i.e. Geneious, BLAST, Samtools, QIIME)
  • Expertise in microbiology, microbial genomics, and/or immunology

At Finch Therapeutics, you can expect to engage deeply in the core of our mission. You will grow with a dynamic, rapidly expanding organization, and have an opportunity to contribute to cutting edge research that will truly impact patients’ lives. We offer a competitive starting salary, plus healthcare and other benefits. As we grow, there will be opportunities for promotion and professional development.

This is a full-time, exempt position with a comprehensive benefits package. You be will be reporting to the Director of Data Science.  

Application Instructions:

The start date for this position is flexible. To apply, please go to http://finchtherapeutics.com/join-finch and submit your cover letter and resume. Promising candidates will be contacted to further evaluate their fit for this role and our organization.

No visa sponsorship is immediately possible, but successful OPTs may be re-evaluated.


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Medical Writer

Date Posted:
5/26/2017

Bluebird Bio

MA

Join bluebird bio’s enthusiastic and collaborative team by contributing to the overall success of our novel gene therapy approach. Reporting to our Senior Director of Medical Writing, this role will provide technical and medical writing support to a variety of regulatory areas that includes CMC, non-clinical, clinical and administrative submissions. The position provides an excellent opportunity to gain experience and learn broad aspects of gene therapy regulations.

Clinical documents will include protocols, Investigator’s Brochures, consent forms, annual reports, clinical study reports, regulatory briefing documents, and clinical sections of regulatory submissions (IMPDs, INDs, CTAs, MAAs and BLAs).  Nonclinical and CMC documents may include technical reports and sections of briefing documents and regulatory submissions.

About the role:

  • Work with the CMC team to prepare sections of the applications related to the manufacture and quality of our gene therapy products
  • Work with the clinical team to prepare protocols, study reports, investigator brochures, and IND/IMPD clinical sections in CTD format under strict timelines.
  • Work with the nonclinical team to prepare nonclinical reports, and nonclinical IND/IMPD sections.
  • Ensure efficient formatting of documents; ensure a consistent style of presentation to maintain quality and ease of review across multiple documents assembled in a regulatory dossier.
  • Contribute to overall project management and to cross functional working groups as needed to facilitate efficient development and finalization of clinical, nonclinical and regulatory documents for submissions.
Requirements

About you:

  • PhD in a Life Science or equivalent, with a solid understanding of the basic principles of biochemistry and molecular biology
  • Fully fluent in spoken and written English; demonstrate the ability to communicate and write clearly, concisely, and effectively
  • Grant and scientific publication writing would be a plus
  • Well-organized: ability to prioritize tasks, to work simultaneously on multiple projects, and to complete high?quality documents according to tight timelines
  • Working knowledge of biologics development and manufacture, clinical research, study design, biostatistics, the regulatory environment, and medical terminology preferred
  • Detailed knowledge of requirements for preparation of key clinical, nonclinical and regulatory documents for INDs, CTAs, BLAs and annual reports would be a plus
  • Proficient in Microsoft Word, Excel, Reference Manager, and PleaseReview
  • Accurate and detail-oriented
  • Aptitude for compilation, analysis, and presentation of data
  • Independently motivated, and good problem-solving ability
  • Ability to work with multiple contributors to produce a final unified document
  • Be ready to embrace the principles of the bluebird bio culture:  b colorful, b cooperative, and b yourself

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Scientist I

Date Posted:
5/26/2017

Palleon Pharma

MA

Job description:

Palleon Pharma seeks a highly motivated and talented antibody engineering scientist to advance discovery research platforms and novel therapeutic programs. The qualified candidate will be a highly motivated, interactive, and creative individual that possesses substantial research experience in antibody discovery and engineering. S/he will keep up-to-date in the literature related to his/her area of expertise act as an expert resource in his/her scientific field and related disciplines.

Position Responsibilities:

•   Perform antibody and protein optimization, including antibody humanization, affinity maturation, stability, activity and sequence liability engineering

•   Design and construct mutagenesis libraries for antibody/protein optimization

•   Develop and conduct high throughput binding/activity/developability screening assays

•   Express antibodies/proteins using mammalian cells in 24/96-well plates and shaking flasks 

•   Purify antibodies/proteins using affinity and ion exchange chromatography

•   Characterize antibodies and proteins using Octet

•   Independently perform complex experiments with strong attention to quality, details and documentation

•   Interpret data, troubleshoot experiments and present work

•   Proactively interact and effectively collaborate with team members from cross-functions

Requirements

Requirements:

•   Ph.D. degree in molecular biology, biochemistry or related field with emphasize on protein/antibody engineering and >3 years postdoctoral experience

•   Experience in antibody discovery, engineering and function characterization

•   Experience and knowledge in protein expression, purification, and characterization

•   Strong understanding of antibody structure and function

•   Extensive experience in molecular biology techniques

•   Experience utilizing structural modeling and sequence analysis software for antibody/protein optimization, de-immunization, assessment of manufacturability

•   Good understanding of immunology/oncology and drug development process

•   Well-organized, self-directed and self-motivated with “can-do” attitude

•   Ability to work in a creative and fast-paced culture and productive team environment

•   Team player with strong interpersonal skills and high ethical standard 

Who We Are:

Palleon Pharmaceuticals is focused on developing protein drugs aimed at novel targets in diseases characterized by dysregulated innate and adaptive immunity. The company has raised substantial capital from several large and established investors.


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Assistant Director, Career Development

Date Posted:
5/26/2017

University of Massachusetts Medical School

MA

Under the general direction of the Assistant Dean for Career & Professional Development or designee, the Assistant Director for the Center for Biomedical Career Development is responsible for the development and management of career development programs that serve Graduate Students and Post-Doc Associates.


									
Requirements

MAJOR RESPONSIBILITIES:

  • Direct the development and implementation of new and continuing career development programs designed to help graduate students and postdoctoral scholars identify and prepare for their future careers
  • Assist in developing and enacting a strategic plan for growth and sustainability of the Center
  • Direct special projects for the Center: proposing a strategic plan, defining metrics, reporting progress, and coordinating Center-wide implementation for special project area(s)
  • In collaboration with the Assistant Dean and program evaluation team gather and analyze program evaluation data and disseminate findings to educators regionally and nationally
  • Develop and maintain an effective relationship with program development staff, trainees, faculty, academic leadership, and external partners in the private and public sector to advance the mission of the Center
  • Manage staff and lead teams
  • Ensure that new program development and project completion is timely, successful, and meets expectations
  • Coordinate implementation of educational programs including but not limited to defining learning objectives, identifying speakers, developing publicity, managing logistics, grading and upholding curriculum requirements (where applicable)
  • Develop new and maintain existing educational resources, including print and online materials
  • Teach in large classroom, small group, and individual settings (including career counseling)
  • Document and maintain current: program development reports and decisions, lesson plans and materials, correspondence with trainees and key partners, educational evaluation reports, budget reports, and other pertinent reports
  • Develop marketing materials to promote educational objectives and advance the mission of the Center
  • Write grants to support program implementation, innovation, evaluation, and research efforts of the Center
  • Represent the department on committees or at meetings and conferences at the university, regional, national, and international levels.
  • Perform other duties as required.

 

 

 

REQUIRED QUALIFICATIONS:

  • Master's degree in a scientific discipline, educational leadership, counseling, communication, a related degree or equivalent experience
  • 3 years of related experience developing, managing, and implementing complex projects or programs
  • Demonstrated strategic planning skills and initiative in developing/implementing strategies to reach goals
  • Experience with the development of curricula or educational resources
  • Demonstrated analytical skills and independent judgment.
  • Demonstrated skills in teaching and individual advising
  • Demonstrated ability to lead and direct multidisciplinary groups
  • Demonstrated ability to meet project deadlines, assess priorities, and operate in a flexible manner in order to meet the dynamic needs of the department
  • Excellent oral and written communication skills, including presentation, professional correspondence, and networking
  • Innovation, flexibility, and creativity
  • Demonstrated experience developing strategic professional relationships and managing a broad network across academic, public, or private sector entities
  • Excellent computer/technical skills
  • Ability to be discreet and handle confidential information

PREFERRED QUALIFICATIONS:

 

  • PhD in a scientific discipline, educational leadership, counseling, or communication, or equivalent experience and 1 year of related experience
  • Prefer experience using MS Office products (Word, Excel, PowerPoint, and Outlook), web development tools, and social media
  • Prefer knowledge of research culture in academic and industry settings
  • Prefer experience developing and managing programs in the area of career development
  • Prefer experience writing media communications, research manuscripts, and grant proposals.

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Principle Scientist Flow Cytometry

Date Posted:
5/26/2017

Pfizer

MA

A career at Pfizer offers opportunity, ownership and impact. All ove r the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.

Role Description
The Inflammation and Immunology Research Unit (I&I) is establishing a new Flow Cytometry Technology Center that will support the entire research community at the Cambridge, MA site and will be managed by a dedicated Technology Specialist/Immunologist. This technology expert/immunologist will support an extensive portfolio of programs within I&I and other research units as well as oversee the operations of the Flow Cytometry Technology Center. The successful candidate will combine a strong technical grounding in flow cytometry with a deep scientific understanding of immunological mechanisms of disease.

Responsibilities
* Oversee the general operation of the Technology Center
* Serve as a technical, scientific and strategic advisor to project teams for flow cytometry and immunophenotyping * Proactively respond to project team needs to elucidate molecular mechanisms of action
* Work closely with external vendors around new technologies and instrumentation
* Manage a broad array of flow cytometry and cell sorting equipment, including training users and managing workflows
* Serve as an interface to Global Operations for equipment and facilities support
* Mentor and develop less experienced staff to drive team success
* Implement continuous improvement to improve quality, efficiency and manage costs

Qualifications
* PhD in immunology, cell biology or related field with 3+ years relevant experience in a flow cytometry
* Strong background in immunology and immunologic basis for human disease
* Proven track record of publications in top-tier journals
* Excellent interpersonal skills, experience as a manager and the ability to explain systems and train staff at all levels
* Demonstrated ability to work effectively as a part of a cross-functional team
* The attitude of self-directed scientist; demonstrated ability to multitask, prioritize work and manage a number of projects Technical Skill Requirements
* Strong background in flow cytometry analysis and cell sorting
* specifically BD LSRFortessa, BD FACSAria and Sony SH- 800 instruments -Experience IntelliCyt iQue screening systems preferred
* Experience with CyTOF and associated data analysis preferred
* Strong background in data management and analysis including FACSDiva, FlowJo and Forecyt
* Demonstrated ability to effectively deal with ambiguity and change
* Experience managing equipment and troubleshooting issues before engaging technical service
* Expertise in data management, data aggregation, analysis & workflow management
* Experience with in vitro pharmacology data analysis, Activity Base and Biobook preferred


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Scientific Information and Literature Analyst

Date Posted:
5/26/2017

Alkermes

MA

Alkermes plc is a fully integrated, global biopharmaceutical company developing innovative medicines for the treatment of central nervous system (CNS) diseases. The company has a diversified commercial product portfolio and a substantial clinical pipeline of product candidates for chronic diseases that include schizophrenia, depression, addiction and multiple sclerosis. Headquartered in Dublin, Ireland, Alkermes plc has an R&D center in Waltham, Massachusetts; a research and manufacturing facility in Athlone, Ireland; and a manufacturing facility in Wilmington, Ohio. For more information, please visit Alkermes’ website at  www.alkermes.com  .    

Position Summary:

Alkermes seeks an innovative and service oriented professional to join the Medical Affairs department as a Scientific Analyst for Knowledge Management Services/Scientific Affairs. As a Scientific Analyst in the Knowledge Management Services/ Scientific Affairs group, the individual will play a key role in supporting Alkermes Global R & D organization in review of the daily, weekly, and monthly literature alerts and information with respect to peer reviewed publications,  conferences proceedings,  guidelines and  other relevant information to support clinical development programs, product pipeline and marketed products.

Responsibilities:

The successful candidate will maintain strong awareness of organizational needs, be willing to proactively and assertively assist in providing, archiving and disseminating information in a timely fashion via ad hoc alerts, the weekly Science Surveillance literature review, the weekly Clinical Trial alert and special announcements. They would also work in conjunction with the Medical Affairs team as needed in assisting in the preparations for conference bootcamp materials, and dissemination of prior/post conference proceedings of interest to Alkermes Global R&D.

 

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Scientist Developmental and Molecular Pathways

Date Posted:
5/26/2017

Novartis

MA

We seek a talented, highly motivated candidate to join a dynamic team engaged in discovering new targets in various molecular pathways. The candidate will focus on identification, validation, and progression of targets in diseases areas associated with these signaling pathways. The candidate will work with multidisciplinary teams focused in particular disease or technology areas to accomplish these objectives. Multiple scientific approaches will be employed in the pursuit and characterization of novel targets including, but not limited to, high-throughput cell-based screening, proteomics, genomics, small molecule interventions, viral-based cDNA overexpression, and CRISPR-based genetics. Utilization of in vitro reactions, cell-based assays and various model organisms will be considered in research workflows. The scientist will be involved in designing, implementing and advancing scientific experiments, and should be able to provide critical analysis of data. The scientist will also provide technical mentoring and expertise to other research staff in the group. The scientist will report results of studies and make recommendations to scientific leaders in a timely, thorough, and coherent manner.

Requirements
• M.S. in Molecular Biology, Biochemistry or Cell Biology 
• Minimum 5 years research experience in the aforementioned research areas 
• Previous experience with standard molecular biology and protein biochemistry techniques (e.g. DNA cloning, protein purification, qPCR, Western blotting, immunoprecipitation, enzymatic assays) is required. 
• Previous experience with standard cell biology techniques (e.g. general cell culture, stable cell line production, viral transduction, high-content immunofluorescence imaging, FACS, RNAi/CRISPR techniques, proliferation/viability monitoring) is required. 
• Previous experience with signal transduction, compound MOA study, primary cell and organoid culture, and mouse models is preferred.
The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.
 

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Scientist, Investigator Age Related Disorders

Date Posted:
5/26/2017

Novartis

MA

We seek a talented, highly motivated candidate to join a dynamic team engaged in discovering new targets in various molecular pathways. The candidate will focus on identification, validation, and progression of targets in diseases areas associated with these signaling pathways. The candidate will work with multidisciplinary teams focused in particular disease or technology areas to accomplish these objectives. Multiple scientific approaches will be employed in the pursuit and characterization of novel targets including, but not limited to: cellular and biochemical assays and assay development; molecular biology – preparation of vectors to overexpress or knockdown expression; CRISPR-mediated cellular knockouts; high-throughput cell-based screening, proteomics, genomics, small molecule interventions, cDNA overexpression, and CRISPR-based genetics. Utilization of in vitro reactions, cell-based assays and various model organisms will be considered in research workflows. The scientist will be involved in designing, implementing and advancing scientific experiments, and should be able to provide critical analysis of data. The scientist will also provide technical mentoring and expertise to other research staff in the group. The scientist will report results of studies and make recommendations to scientific leaders in a timely, thorough, and coherent manner.

Requirements

• B.S. or M.S. in Molecular Biology, Biochemistry or Cell Biology 
• Minimum 5 years research experience in the aforementioned research areas 
• Previous experience with standard molecular biology and protein biochemistry techniques (e.g. DNA cloning, protein purification, qPCR, Western blotting, immunoprecipitation, enzymatic assays) is required. 
• Previous experience with standard cell biology techniques (e.g. general cell culture, stable cell line production, viral transduction, high-content immunofluorescence imaging, FACS, RNAi/CRISPR techniques, proliferation/viability monitoring) is required. 
• Previous experience with signal transduction, compound MOA study, primary cell and organoid culture, and mouse models is preferred. 
• Must be highly motivated, team-oriented, and have excellent interpersonal and communication skills.

 
 

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Scientist

Date Posted:
5/26/2017

AngieX

MA

Angiex is an innovative science-focused startup developing vascular therapies for cancer and chronic inflammatory conditions; the lead product is an antibody-drug conjugate therapy for cancer. Angiex was recently launched out of Beth Israel Deaconess Medical Center, is resident at LabCentral in Cambridge, and has $3.6 million in Series A funding led by Thiel Capital. Angiex founders have previously discovered VEGF-A, been recognized as the world’s leading experts in tumor blood vessel biology, developed new methods for per cell mRNA quantification, founded four companies, written a best-selling diet book, and won second prize for best salsa recipe at LabCentral.

Job Description:

Angiex is seeking a talented, creative, self-motivated scientist with a background in protein therapeutics to join in the discovery and pre-clinical development of antibody-based drugs. The successful candidate will be responsible for laboratory aspects of biologic drug development including antibody production, purification, and characterization; ADC linker, spacer, payload, and conjugation chemistry evaluation; experiments to elucidate target biology; and management of CROs. The job offers exceptional opportunity for career development in one of Boston’s most exciting and promising biotech startups.

Responsibilities:

  • Design and conduct experiments through all stages of discovery and development of antibody-based therapeutics, including evaluation of antibodies, linkers, payloads, conjugation methods, and CROs. Specific responsibilities include:
    • Design, cloning, transfection, expression, and purification of antibodies.
    • Evaluate antibodies, fragments, and ADCs for biochemical and biophysical characteristics including stability, affinity, kinetics, and binding epitopes.
    • Oversee antibody humanization and affinity maturation.
    • Perform assays in support of pharmacokinetic, pharmacodynamic, and anti-drug antibody studies.
    • Develop assays required to support GMP manufacturing of biologics.
  • Be talented enough to rapidly master tasks you’ve never done before, cooperative and communicative enough to make a great team even stronger, dedicated enough to accomplish in one week what others do in two, careful enough that experimental results are reliable, honest enough to say when they aren’t, creative enough to wake up at 3 am with ideas you can’t wait to share, and cheerful enough to enjoy to the fullest the most exciting job you’ll ever have.
  • Cure cancer.

Statement:

Angiex is an equal employment opportunity employer and does not discriminate against any applicant because of race, creed, color, age, national origin, ancestry, religion, gender, sexual orientation, disability, genetic information, veteran status, military status, application for military service or any other class protected by state or federal law.

Requirements

Requirements:

  • Ph.D. in biology, chemistry, biochemistry, immunology, or a related discipline with substantial experience in wet-bench laboratory work and a strong record of accomplishment.
  • At least 2 years, preferably 5 to 10 years, of biopharmaceutical experience in the development of antibody-based drugs, preferably including experience with antibody-drug conjugates.
  • Familiarity with regulatory requirements for biologics.
  • Highly self-motivated, talented, versatile, with excellent oral and written communication skills, ability to multi-task and excel in a fast-paced environment.
  • Ability to work independently yet team-oriented; capable of building strong relationships with peers within the firm and partners outside the firm; a preference for working in a highly communicative and cooperative team; honesty, transparency, humility, integrity.

Application: Please email cover letter and CV to jobs@angiex.com.


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Scientist Immunology

Date Posted:
5/26/2017

Magenta Therapeutics

MA

The successful candidate will be an integral member of a team developing novel therapeutics to transform hematopoietic stem cell transplantation science. This challenging opportunity requires in depth knowledge of auto-immunity, T cell biology and graft vs host disease. The position requires excellent written and verbal communication skills and the ability to work effectively in a multi-disciplinary team. The ideal candidate will be creative, rigorous, goal oriented and prepared to be immersed in a fast-paced and innovative environment that offers the opportunity to work and publish.

Requirements
  • Ph.D. with a strong background in immunology, hematology or similar field.
  • Extensive experience with in vitro models of auto-immunity and graft vs host.
  • Knowledge of mouse and human hematopoiesis, including hematopoietic stem cell differentiation, is highly desirable.
  • Hands on experience analyzing complex immunophenotypes.
  • Understandng of current research in T cell depletion and Selective depletion of alloreactive T cells.
  • Expertise in using FACS analysis to interrogate blood lineage populations using cell surface markers is required.
  • Experience using in vivo models of auto-immunity required.
  • A strong track record of success as demonstrated by high impact publications and project leadership is highly preferred.

 We offer competitive compensation along with a comprehensive benefits package. To apply, please submit your resume to careers@magentatx.com


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Scientist II Pharmcology

Date Posted:
5/26/2017

Immunogen

MA

ImmunoGen is a clinical-stage biotechnology company that develops targeted cancer therapeutics using its proprietary antibody-drug conjugate (ADC) technology. ImmunoGen’s lead product candidate, mirvetuximab soravtansine, is being advanced to a Phase 3 trial for FRα-positive platinum-resistant ovarian cancer, and is in Phase 1b/2 testing in combination regimens for earlier-stage disease. ImmunoGen’s ADC technology is used in Roche's marketed product, Kadcyla, in three other clinical-stage ImmunoGen product candidates, and in programs in development by partners Amgen, Bayer, Biotest, CytomX, Lilly, Novartis, Sanofi and Takeda.  More information about ImmunoGen can be found at www.immunogen.com.

The Opportunity

ImmunoGen, Inc. is searching for a talented and motivated Scientist to join the Pharmacology group. The successful candidate will play a key role in the evaluation of novel antibody-based therapeutics.  This position offers the opportunity to work in a dynamic, collaborative team environment while interacting with other groups across the entire Research and Development organization.  The person filling this role will be responsible for defining and guiding the project teams’ preclinical in vivo strategy; will plan and execute, as well as coordinate and supervise, efficacy, PD and PK in vivo studies; and will track and communicate progress on in vivo study time lines and key deliverables.

ImmunoGen, Inc. is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital and veteran status.

ImmunoGen, Inc. does not accept non-solicited resumes or candidate submittals from search/recruiting agencies not already on ImmunoGen, Inc.’s approved agency list. Unsolicited resumes or candidate information submitted to ImmunoGen, Inc. by search/recruiting agencies not already on ImmunoGen, Inc. approved agency list shall become the property of ImmunoGen, Inc. and if the candidate is subsequently hired by ImmunoGen, Inc., ImmunoGen, Inc. shall not owe any fee to the submitting agency.

Requirements

Who You Are

The qualified candidate will hold a PhD in Pharmacology, or related discipline, and will have 3-5 years of post-graduate experience, preferably in the pharmaceutical/biotechnology industry.  The candidate will possess excellent in vivo skills, with experience in xenograft/ syngeneic tumor models; a solid understanding of experimental design and data analysis; proven written and oral communication skills; and strong time management skills. Experience with PK/PD modeling and murine toxicology models would be desirable. Previous supervisory experience is preferable.


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Scientist I Process Chemistry

Date Posted:
5/26/2017

Macrolide Pharma

MA

Macrolide has two positions open for Scientists in our Process R&D group. These positions are hands-on, laboratory positions who will be responsible for designing innovative routes to complex small molecules followed by conducting process research and development to assure safe and consistent manufacturing at large scale. Manufacturing at kilo-scale in our in-house facility is a part of the responsibilities along with collaboration and technology transfer to external vendors for scale-up. The candidate should have a strong record of accomplishment in organic chemistry, including a track record of publications demonstrating innovative and creative solutions to problems.

Requirements

Key Responsibilities:

• Process Chemistry R&D
• Route design/innovation
• Collaborates with members of the process chemistry team and external collaborators to assure timely delivery of material
• Author of technical documents

Minimum Qualifications
• Ph.D. with 0-6 years of process chemistry experience or MS with 2+ years experience
• Background in organic chemistry
• Some travel required

Preferred Qualifications
• Experience in process chemistry R&D including interactions with CMOs desired
• Scale-up and technology transfer experience
• GMP experience

 

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Postdoctoral Fellow Stress Hormone Signaling

Date Posted:
5/26/2017

NIEHS

NC

2 POSTDOCTORAL POSITIONS AVAILABLE

STRESS HORMONE SIGNALING IN MULTIPLE ORGAN SYSTEMS

NATIONAL INSTITUES OF ENVIRONMENTAL HEALTH SICENCES, RESEARCH TRIANGLE PARK, NORTH CAROLINA

Position Description:
Two post-doctoral positions will be available in September 2017 to study molecular mechanisms of stress hormone actions in genetically modified animals. The positions are in the Molecular Endocrinology section of the Signal Transduction Laboratory under the direction of Dr. John A. Cidlowski. We strive to define cell type specific actions of glucocorticoids and their mechanisms of control of inflammation and homeostasis in mouse models and in humans.

Qualifications:

Qualifications:
Applicants must have a PH.D., M.D., or D.V.M degree and less than 4 years of post-doctoral experience. We seek motivated, enthusiastic colleagues who enjoy independence. We have world-class facilities and a highly interactive research environment with exceptional resources. Expertise in molecular biology and the use of animal models are a plus. Documented evidence of peer reviewed publications is essential for consideration.

To Apply:

To Apply:
Candidates should submit a CV including contact information for 3-4 references, to:

Dr. John A. Cidlowski
Chief, Signal Transduction Laboratory
National Institute of Environmental Health Sciences,
Research Triangle Park, North Carolina
Email: cidlows1@niehs.nih.gov

Further information about our laboratory and Signal Transduction Laboratory can be found at https://www.niehs.nih.gov/research/atniehs/labs/stl/index.cfm


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Scion Neurostim Consultant

Date Posted:
5/26/2017

Scion Neurostim

NC

Scion NeuroStim (SNS), a startup company utilizing a non-invasive neuromodulation device to address neurological diseases and disorders, is seeking a full-time consultant to participate in its work plans for a period of at least one year. Multiple clinical studies have been conducted, and others are being planned.

Job Duties:

Responsibilities would include participation in the following activities:
Planning and execution of clinical trials using the Company’s device platform
Analysis of study data and communicating findings to clinical collaborators
Preparation of research grant applications
Planning and conducting current and future research projects using the device
Preparation of publications
Active participation as a team member

Qualifications:

Background:
Ph.D., ideally in life science
Some post-doc experience ideal
Background of first-author publications
Direct experience with writing research grants
Good organizational skills
Commitment to effective collaboration working in a team setting

Contact Info:

Forwarded on behalf of Robert Black [mailto:rblack@scionneurostim.com] 

To Apply:

Contact:
Robert Black
Scion NeuroStim
rblack@scionneurostim.com
Raleigh, NC


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Postdoctoral Fellow Lung Immunology

Date Posted:
5/26/2017

NIEHS

NC

Position Type: Postdoctoral Position at the NIEHS/NIH in Research Triangle Park, NC

Position Title: Lung Immunology

Employer Name: National Institute of Environmental Health Sciences, National Institutes of Health

Position Location: Research Triangle Park, North Carolina

The NIH is dedicated to building a diverse community in its training and employment programs.

Job Duties:

Position Description: Applications are invited for a fellowship in pulmonary immunity.  Focus will be on defining novel mechanisms for cholesterol and related lipids in innate and adaptive immune responses in the lung.  Studies will involve gene-targeted mice in in vivo challenges, complemented by ex vivo cellular/molecular studies.  

Qualifications:

Expertise with in vivo rodent techniques and multicolor flow cytometry are strongly preferred; a strong background in immunology research is also favored.  Applicants should possess a Ph.D. degree in Immunology, Molecular Biology, Biochemistry, Pharmacology, or a related field, and have no more than five years of previous postdoctoral experience.  

To Apply:

For additional information about this position, contact Dr. Michael B. Fessler at email below.  For prompt consideration, please email a cover letter including a brief summary of relevant experience, a C.V. including list of publications in peer-reviewed journals, and the names and contact information of 3 people who could provide letters of reference to: fesslerm@niehs.nih.gov


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Postdoc Immunotherapy Neuro Oncology

Date Posted:
5/26/2017

NCI

MD

A postdoctoral position is available in the NIH-NCI Immunotherapy Section of the Neuro-Oncology Branch. Please see the attached announcement for more information or visit the following websites:

Position Announcement: https://ccr.cancer.gov/careers/postdoctoral-fellow/18363?
Neuro-Oncology Branch: https://ccr.cancer.gov/Neuro-Oncology-Branch

Department of Health and Human Services National Institutes of Health National Cancer Institute Center for Cancer Research Postdoctoral Fellow Neuro-?-Oncology Branch Deadline: Open Until Filled The Neuro-?-Oncology Branch (NOB), Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Department of Health and Human Services (HHS), is seeking an outstanding postdoctoral candidate for laboratory research related to brain tumors. The NOB is comprised of a multidisciplinary team of physicians, healthcare providers, and scientists who are dedicated to developing new therapies and improving outcomes for patients with primary brain and spinal cord tumors.

A postdoctoral position is available in the Immunotherapy Section of the NOB laboratory in its exciting translational, interdisciplinary research team. This postdoctoral fellowship emphasizes the development of hypothesis-?-driven translational projects that interrogate the role of immunologic fitness, tumor type, tumor grade, and treatment history in response to immune therapy. These studies are integral to the global efforts in cancer immunotherapy and will be used to drive anti-?-tumor immunity research and to improve clinical trial design and patient treatment.

Job Duties:

This is an exciting opportunity to perform immunologic studies in ongoing immunotherapy clinical trials at the NIH. The successful applicant will identify relevant immune subsets that correlate with clinical response to immune-?-modulating agents and will also have the opportunity to be involved in basic and translational projects to understand the mechanisms behind a successful anti-?-tumor immune response. The NOB promotes a collaborative environment between clinicians and scientists both within and outside the NIH. This position will also entail close collaboration with a Senior Investigator and world-?-renowned expert in flow cytometry at the National Institutes of Allergy and Infectious Diseases (NIAID), thereby providing an outstanding opportunity to develop expertise in this exciting area of research.

Qualifications:

The NOB is seeking a creative and bright individual who has a keen interest in making a substantial contribution to the understanding of immunology and brain tumor biology. Applicants must have a Ph.D. or M.D./Ph.D. degree. Successful applicants should have a strong background in immunology, mouse models, and molecular biology, with priority given to candidates with experience in statistical analysis and computational biology. Stipend will be commensurate with education and research experience.

To Apply:

Interested candidates should send a curriculum vitae, statement of research interests, and three letters of reference to the attention of: Mark R. Gilbert, M.D., Neuro-?-Oncology Branch, National Cancer Institute, 9030 Old Georgetown Road, Building 82, Room 235A, Bethesda, MD 20892, or to: NCINeuroOncology@mail.nih.gov. Visit the Neuro-?-Oncology Branch website at https://ccr.cancer.gov/Neuro-?-Oncology-?-Branch. HHS, NIH, and NCI are Equal Employment Opportunity Employers


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Senior Fellow Immunology

Date Posted:
5/26/2017

University Washington

WA

Description:

Senior Fellow Position Available at the UNIVERSITY OF WASHINGTON, Department of Immunology, Seattle, Washington

Job Duties:

The laboratory of Professor Edward A. Clark currently has a Senior Fellow position available for a scientist interested in investigating innate immune programming of B cell and humoral immune responses. The lab has prepared a unique set of reagents and mouse lines including B cell-activating factor (BAFF) reporter mice and BAFF and MAVS floxed mice that have been crossed to Cre lines to selectively remove BAFF or MAVS expression from B cells, dendritic cells (DCs) or myeloid cells. The roles of BAFF in both autoimmune and infectious disease models including West Nile virus and Salmonella) are being explored. 

Qualifications:

The position is available immediately for a Ph.D. level scientist preferably with some postdoctoral experience. Candidates must have a Ph.D. in biological science area and preferably some experience in immunology, molecular biology and/or mouse models of autoimmune disease or infection.

To Apply:

Please request more information or send your c.v. to Dr. Edward A. Clark at eaclark@uw.edu or call Dr. Clark for more information at 206-962-1582.

The laboratory is within a new building located in the dynamic South Lake Union (SLU) area, which contains the Department of Immunology as well as Divisions of Rheumatology and Infectious Diseases within the Department of Medicine. The SLU area has a number of biomedical research institutes and biotech companies adding to a very interactive, creative research environment. Our Center for Innate Immunity and Immune Disease (CIIID) has over 50 faculty members and coordinates and assists world-class innate immunity research programs. Dr. Clark has trained 75 postdoctoral fellows and graduate students and is dedicated to training and helping his postdoctoral fellows develop their careers. He has helped to start three biotech companies and interested in translating research findings.


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Faculty Position Immunology

Date Posted:
5/26/2017

University Chicago

IL

The University of Chicago\’s Department of Pathology invites applications for two faculty positions with a focus on immunology. Our Department of Pathology and Committee on Immunology comprise numerous immunologists with diverse interests who are available for collaboration and mentoring. Appointment will be as tenure-track Assistant Professor or as Associate Professor with tenure, depending on qualifications. 

Qualifications:

Successful candidates must possess a Ph.D. or M.D. or foreign equivalent. Candidates will be required to teach undergraduate and/or graduate students and expected to develop a strong, extramurally-funded research program.

To Apply:

INTERESTED APPLICANTS MUST APPLY ONLINE, including a curriculum vitae and statement of research interest at: http://tinyurl.com/UC-Immunology 

Review of applications will continue until the positions have been filled. 

Search Contact: Daniel A. Arber, M.D., Professor and Chair Department of Pathology The University of Chicago 5841 South Maryland Ave., MC 3083 Chicago, Illinois 60637 

The University of Chicago is an Affirmative Action/Equal Opportunity/Disabled/Veterans Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national or ethnic origin, age, status as an individual with a disability, protected veteran status, genetic information, or other protected classes under the law. For additional information please see the University\’s Notice of Nondiscrimination at http://www.uchicago.edu/about/non_discrimination_statement/. Job seekers in need of a reasonable accommodation to complete the application process should call 773-702-0287 or email ACOppAdministrator@uchicago.edu with their request. 

http://tinyurl.com/UC-Immunology


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Research Scientist HSC Biology

Date Posted:
5/26/2017

Novartis

MA

The Novartis Institutes for Biomedical Research (NIBR) is recruiting an innovative bench scientist to join a research team that will be building and developing novel technologies to develop ex vivo stem cell therapeutics used in the treatment of a range of genetic diseases. The candidate will be involved in developing techniques and processes for the successful translation of this technology into the clinic. This position requires experience with murine or human hematopoietic stem cell (HSC) biology in order to establish in vitro and in vivo models needed for the characterization of product candidates. This position will also evaluate diverse approaches for gene delivery into HSC including CRISPR/Cas9 technology to examine the regulation of hematopoiesis in transplant models. The ideal candidate should have relevant training in hematology/immunology and proficient in hands-on approaches to study stem cell biology, viral gene transfer, hematopoiesis, and bone marrow transplantation. This position is based within an HSC research group in the Hematology Disease Area of Chemical Biology and Therapeutics Department but will be highly collaborative with other Novartis groups including the Genomics Institute of Novartis Research Foundation, the Clinical Translational Unit in Novartis Development and others. This position will work on a highly, collaborative, multi-disciplinary project team to develop therapeutics to treat a range of genetic diseases with this novel technology.
The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.
Minimum Requirements:

• PhD or equivalent in a scientific discipline such as stem cell, regenerative biology, or molecular biology, or MS with appropriate and relevant years of experience in drug discovery or other related laboratory research
• Experience in a laboratory focused on hematopoietic stem cells
• Self-motivated, enthusiasm for working in an interdisciplinary, collaborative research environment

Competencies:
• Ability to work independently in experimental execution and data analysis
• Ability to perform mouse handling techniques, bleeding, and injection procedures related to HSC research
• Proficiency in molecular cloning, sequence and protein analyses, and real-time PCR
• Proficiency in cell culture, transfection and transduction methods and flow cytometry analyses of blood lineages
• Proficiency in using viral and non-viral based gene transfer methods
• Experience in ex vivo/in vitro and in vivo systems to study HSC biology
• Experience in characterization of gene function using murine models
• Experience in screening, identification, and characterization of small molecules and/or biologics
• Possess in-depth knowledge of literature methodology, instrumentation and underlying principles of hematopoietic stem cell (HSC) biology

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Medical Science Liaison Oncology

Date Posted:
5/26/2017

Novartis

MO

The MSL will build relationships and interact with HCPs in Academic Institutions, including community physicians, medical experts, nurses, and medical groups. The MSL will be responsible to build these relationships and have scientific discussions around pathways and MOA of Novartis products including molecular testing and diagnostics, clinical outcome and benefits and most importantly discuss clinical trials to determine interest in participation and/or feasibilities. The key role of this MSL will be to explore and identify potential sites for clinical trials in all stages of development and to serve as a scientific liaison to the medical/scientific community being responsible for establishing, developing and maintaining relationships with HCPs within the coverage area; ensure the appropriate dissemination of clinical and educational information regarding marketed and pipeline compounds, in a timely, ethical and customer-focused manner; implement scientific and educational strategies in collaboration with colleagues from Medical Affairs and Clinical Operations to support Novartis-sponsored trials and educational initiatives; work to pair our key customer's educational and research needs with available Novartis resources and also providing the latest emerging data in response to specific healthcare professional inquiries.

This position will cover : Missouri, Louisiana and Arkansas.
Travel up to 75%
The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.
Advanced scientific degree (MD, PhD, or PharmD) required or oncology nurse with advanced degree required. Minimum of 5 years Oncology experience with a strong current working knowledge of Oncology preferred. Teaching experience preferred. Previous pharmaceutical industry experience preferred. Knowledge of treatment guidelines, clinical research processes, FDA regulations and OIG guidelines is preferred. Excellent interpersonal communication and presentation skills are required. Ability to network and partner with important external customers, large group practices, medical directors and pharmacy directors is required. Must be able to prioritize and work effectively in a constantly changing environment. Must have the ability to gain customer feedback, uncover business opportunities for Novartis and pair customer's unmet needs with available internal resources. Active membership in professional society is a plus. Must be a strong team player who can effectively interface cross-functionally with Novartis clinical and commercial personnel. Working knowledge of Microsoft Office Suite (Word, PowerPoint, Excel) and associated hardware is required. Travel can be up to 75%.

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Computational Chemistry

Date Posted:
5/26/2017

Novartis

INT

In this position you will work in a state-of-the-art Solid State Chemistry group that incorporates in silico computational modelling tools into the early stage physical form selection process, an integral phase in the drug development cycle. You will work in an interdisciplinary team, generating and interpreting data from modelling/computational simulations and liaising with experimentalists to provide information and knowledge that enables, for example, the systematic modification of crystallization parameters, the control of polymorphism, advancement of physical form selection, and modification of the crystal habit of small organic molecules, specifically active pharmaceutical ingredients (APIs). Through combining an advanced knowledge of various computational and modelling approaches with crystal chemistry, and the drug development process, you would aid in identifying, prioritizing and progressing the most suitable physical forms. The position requires a strong focus on scientific excellence in the area of computational chemistry as well as being able to extract and analyze decision making data associated with the crystal structure of the API to build predictive models based on such information for subsequent verification in a chemistry laboratory.
The position involves close collaboration with internal and external scientists from various disciplines, and cross-functional interactions within technical project teams, broadly covering the chemical, formulation and computational arenas.
Ideally you possess:
- A strong background in applying molecular and/or quantum mechanical modelling tools to small organic molecules for the purpose of modifying and optimizing their solid state properties (e.g. crystal habit, stability, solubility)
- A chemistry background, with knowledge of the physical and chemical requirements to be considered when developing an API (as salt, cocrystal, solvate, hydrate, etc.) for use in toxicological or clinical studies
- Preferably pharma-industry experience
- PhD in a field relevant to the position or equivalent industry experience
- Fluent oral and written English
- Deep and diverse knowledge in the use of computational solid state modelling software (one or more areas of MM, QM, MD) and simulation methods to characterize, and thus ultimately alter, the physical properties of small organic molecules (preferably active pharmaceutical ingredients)
- Knowledge in the applicability of CCDC CSD Suite, Materials Studio, COSMOtherm, OpenEye, Schrodinger packages desirable; additionally, experience in use of chemical toolkits (such as ChemAxon, OEChem, RDkit) and scientific pipelining tools (such as Pipeline Pilot, Knime)
- Programming experience in scripting languages such as Python; knowledge of UNIX/Linux and high performance computing to perform large calculations
- Experience in crystallography (e.g. crystal structure prediction), crystal engineering, materials science or polymorphism would be advantageous
- Evidence of identifying, developing and applying innovative solutions to scientific and technical problems faced in the life sciences

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Postdoctoral Fellow Regenerative Medicine

Date Posted:
5/26/2017

Novartis

CA

A postdoctoral position is available for a highly motivated scientist interested in regenerative medicine with an especial emphasis in cardiovascular and renal disease areas at the Genomic Institute of the Novartis Research Foundation (GNF, Novartis). The objective of the project is to identify and manipulate novel mechanisms underlying aging and organ regeneration. The successful candidate will be embedded in a highly dynamic research lab focusing on improving organ repair by leveraging human stem cells (embryonic stem cells, induced Pluripotent Stem Cells/iPSCs) and cell fate reprogramming technologies based on lineage conversion. The successful candidate will be working with a large group of scientists focused on regenerative medicine across different disease settings. The project will involve state-of-the-art stem cell biology techniques and nuclear reprogramming experiments couple to the generation and analysis of large datasets. The successful candidate will have access to state-of-art equipment, high throughput technologies and proprietary genomics tools at GNF. The successful candidate will also play an essential role in establishing and maintaining research collaborations between GNF and academia. The ideal candidate should have outstanding communication and writing skills, strong passion and commitment to science and the ability to work well in a multidisciplinary team.
The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.
• PhD degree holders, and PhD students in the last year of their thesis work
• Proven ability to independently design, execute and interpret experiments
• Proven knowledge on basic molecular biology techniques (RNA isolation, qPCR, IF, IHC,WB,…)
Preferred
• Working knowledge of stem cells
• First-author publications in leading journals
• Knowledge on epigenetics

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Medical Science Liaison Dermatology

Date Posted:
5/26/2017

Novartis

INT

• Medical Scientific Liaison (MSL) Dermatology is a field-based Medical Affairs Associate of Novartis, who develops peer-to-peer relationships with Medical Experts/Key Stakeholders and members of the scientific community, utilizing scientific and medical evidence-based non-promotional materials. He or she strategically prepares and supports the development, launch and commercialization of Novartis products through scientific exchange, seeking external insight to shape Novartis understanding of the therapeutic environment (Dermatology). He or she responds to unsolicited requests for scientific information and provides clinical trial support. Region: French-speaking part of Switzerland.
The responsibilities of a Medical Scientific Liaison are:
• Provide and discuss scientific information and data with Health Care Professionals (HCP) to ensure quality and accuracy of medical and scientific information on new treatment options including Novartis products and selected areas of therapeutic interest.
• Implement scientific projects according to global, regional or local medical strategies (e.g. epidemiology projects, registries, publications, etc.). Contribute in the development of integrated product strategies and medical affairs plans
• Contribute to identification and mapping of Medical Experts/key stakeholders in line with local strategies.
• Upon investigator request, liaise between potential researcher and the Company on Investigator Initiated Trials (IIT) submission process or requests for research grade substance (Material Transfer Agreements) to support independent clinical/ preclinical research
• Develop peer to peer scientific relationships with HCPs and respond to unsolicited requests for scientific information using approved, non-promotional materials with Medical Experts/Key Stakeholders, HCPs and decision makers
• Provide medical support and training (i.e. disease, product) to Novartis colleagues (e.g. sales force, etc.)
• Master degree with a scientific bio-medical background. (MD, Pharmacist and other life sciences), PhD preferred.
• Near native level of French, very good knowledge of English. Fluent in German preferred (oral and written). Italian is an asset
• Preferably 2-4 years of experience in pharmaceutical industry with good knowledge in medical affairs and/or clinical development.
• Good leadership, planning and management skills, as well as an analytical understanding.
• Good communication and presentation skills.
• Team player and interacts with others with respect and integrity.
• State of the art knowledge in scientific area, as well as knowledge of aspects of drug development, GCP and local regulations.
• Understanding of basic marketing principles and strategies.

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Medical Science Liaison Rheumatology

Date Posted:
5/26/2017

Novartis

INT

Do you want to work for a Global Pharmaceutical company where you will get recognized for your hard work and commitment? Look no further, apply today; Medical Science Liaison (Rheumatology).

This is a 12 month fixed term contract position that sits in the Immunology and Dermatology franchise and covers the South and South West of England.

Job purpose

The Medical Science Liaison (MSL) is a field based, non-promotional medical and scientific role. Their key objective, as a member of the Franchise Team, is to build partnerships with external healthcare professionals (HCP), to communicate evidence based critical scientific, technical and development issues relating to Novartis products/compounds and the therapeutic areas (TAs) they relate to.

Activities include:
• development of partnerships with investigators, opinion leaders and healthcare professionals through scientific, evidence based communication and education
• clinical trial activities – selection and facilitation
• investigator-initiated studies (IITs) – accountable for milestone delivery
• scientific projects & research
• Support of PDT in providing deep market and clinical understanding of pipe-line therapeutic areas
• publications (abstracts, posters, case studies and peer reviewed papers)
• input and/or attendance at medical educational programmes, advisory boards & training


Key Responsibilities

• Management of External Partnerships
• Develop and maintain long term professional relationships with investigators, opinion leaders and healthcare professionals
• Utilizes superior therapy area and product knowledge to engage with HCPs through non-promotional evidence based scientific dialogue and presentations
• Develop scientific research concepts and ideas with investigators and deliver new data to enhance company product knowledge
• Speaker training to ensure scientific and medical accuracy
• Collaborate with Novartis colleagues to actively support medical and scientific meetings by collecting and interpreting insights competitive intelligence /presentations/ results
• Pipeline support - Provide medical expertise as part of a cross functional team to relevant clinical development studies, including:
- Feasibility and quality research site recommendations
- TA/product training for site staff o Medical educational activities to support patient recruitment
- Strategic support for priority trials
- Dissemination of study results

• Internal Novartis Leadership
• Close cross functional working with office medical colleagues and Sales and Marketing
• Medical support to Brand Franchise team as required
• Acts as a field-based reference point for non-promotional scientific and clinical expertise to field force
• Be alert to potential Business Development opportunities and inform relevant internal teams
• Scientific Projects
• Identify and track potential research opportunities closely aligned with Novartis molecule development objectives through facilitating IITs and MTA research as agreed by Medical TA Head
• Implement and/or support scientific projects according to corporate global strategies, including registries, epidemiology projects, preclinical or translational research
• Corporate image and Compliance
• Ensure that prevailing legislation, GCP, Ethical Committee, and SOP and local WP requirements, and ABPI Code of Practice requirements are fulfilled
• Contribute proactively to a credible image for Novartis CPO in the local Health Care and Medical community
• Adheres to Novartis Code of Conduct

#LI-NOV

About Novartis

Our mission is to care and cure; We want to discover, develop and successfully market innovative products to prevent and cure diseases, to ease suffering and to enhance the quality of life. We also want to provide a shareholder return that reflects outstanding performance and to adequately reward those who invest their money, their time and their ideas in our company.

Benefits of Working for Novartis

Competitive Salary, Annual Bonus
Strong Work/Life Balance, flexible working – Top UK Employer
Pension Scheme, Share Scheme
Paid holidays, Comprehensive Medical Insurance
Subsidized Canteen
Employee Recognition Scheme
Sports & Social Club

‘I came for the job, I stay for the culture’
The ideal candidate will have:

- Ideally, BSc (Hons) and significant medical/clinical experience or BSc (Hons) + MSc Desirable: PhD, MRPharmS, MB BS, MB ChB
- 1. Ideally an MSL should be either medically qualified or a qualified pharmacist or possesses a PhD qualification (scientific/medical background) or - possesses a scientific qualification with significant medical/clinical experience
- 2. The ability to understand, process, communicate and present scientific information to a high standard. Possess excellent presentation skills
- 3. Demonstrate an ability to be accountable for all scientific and clinical activities undertaken with a respective clinician, developing an appropriate strategic plan for these activities
- 4. External customer focus with strong networking capabilities and integration with KOLs
- 5. Understanding of Pharma Industry ways of working
- 6. Understanding of clinical development and Good Clinical Research Practice preferred
- 7. Excellent influencing, networking, presentation and communication skills and a proven track record of team cross-functional team working
- 8. Ability to manage multiple projects and adapt priorities accordingly

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Medical Science Liaison Respriatory

Date Posted:
5/26/2017

Novartis

INT

THIS IS A TEMPORARY 12 MONTHS CONTRACT POSITION

Medical Science Liaisons (MSLs) are Field-based Medical Affairs Associates of Novartis, who develop peer-to-peer relationships with Key Opinion
Leaders/Medical Experts/Key Stakeholders and members of the scientific community, utilizing scientific and medical evidence-based non-promotional materials. They strategically prepare and support the development, launch and commercialization of Novartis products through scientific exchange, seeking external insight to shape Novartis understanding of the therapeutic environment. Their activities begin up to two years prior to launch of a new molecule. They respond to unsolicited requests for scientific information and provide clinical trial support. Additionally, MSLs participate and often lead special projects and specific initiatives, leveraging their extensive experience and strategic insight.

KOL Management & Medical Support
1. Using advanced communication skills, develop peer to peer scientific relationships, assess advocacy and contributions and respond to unsolicited requests for scientific information using approved, non-promotional materials with Key Opinion Leaders (KOLS), Health Care Professionals (HCPs) and decision makers. They demonstrate the ability to manage challenging situations and interactions.
2. Contribute to and/or lead the identification and mapping of KOLs/key stakeholders in line with local strategies.
3. Provide and discuss advanced level scientific information and data with HCPs to ensure quality and accuracy of medical and scientific information on new treatment options including Novartis products and selected areas of therapeutic interest.
4. Liaise and provide up-to-date medical support to relevant internal and external groups to ensure evidence based understanding of Novartis products relative to medical guidelines, and health economic information.
5. Provide speaker training to HCPs to support the best use of new therapies developed and commercialized by Novartis.

Scientific Research Support
6. Lead initiatives and provide strategic medical support, as part of a cross functional team to enhance the quality of relevant clinical trials.
7. Provide scientific educational activities to support study accrual for key trials as appropriate.
8. Provide feasibility and research site recommendation for Novartis sponsored clinical trials.
9. Collaborate with ICRO team and Medical Advisors, to support clinical sites, including providing guidance in accordance with guidelines, Novartis Internal Policies, and regulations as appropriate.
10. Increase awareness of Novartis clinical research program to enhance patient identification and trial accrual
11. Upon investigator request, liaise between potential researcher and the Company on IIT submission process or requests for research grade substance (MTAs) to support independent clinical/preclinical research.

Scientific Exchange/Insights
12. Engage in scientific discussions related to Novartis compounds/pipeline with MEs, speakers & investigators.
13. Support scientific exchange to advance understanding of new scientific principles, novel research trends, and current scientific debate.
14. Provide scientific and educational information to healthcare professionals on specific patient critical issues.
15. Collect, analyze and report insights that may impact Novartis development plans /trial designs, launch strategies and tactics and medical education programs tailored to physicians' education needs

Scientific Projects
16. Provide scientific support to KOLs upon their request
17. Implement scientific projects according to global, regional or local medical strategies. Examples may include, but not limited to, epidemiology projects, registries, preclinical or translational research, as well as multi-disciplinary projects involving education and collaboration of multiple functions in the medical community to improve patient diagnosis and treatment.

Internal Novartis Support
18. Provide medical support and training (i.e. disease state and product) to Novartis colleagues (e.g. sales reps, CRAs, etc.).
19. Support, mentor and train Novartis colleagues in successful interactions with KOLs/MEs, and share best practices.
20. Serve as a resource/and or team leader for projects and collaborate with internal colleagues as assigned by SciOps Head/or therapeutic area teams. (Serve as medical expert on cross-functional teams).
• COMPULSORY: Associate shall be accountable to perform all duties listed in Role Profile in accordance with applicable GxP principles, and internal/external regulations (e.g. Novartis Code of Conduct, Novartis Pharma Principles and Practices for Professionals (NP4), Rx&D Code of Ethical Practices, Health Canada and all other relevant regulations).

Education:
- MD, PharmD, pharmacist, PHD and other life sciences with solid medical/technical background and proven competencies influencing skills, clinical research insight, business and market knowledge.
- Be considered as a peer of the customer base

1. Proven competency and successful experience as a MSL.
2. An advanced proven ability to develop and foster peer-to-peer, credible relationships with KOLs/decision makers.
3. Ability to coach and mentor field medical colleagues. Perceived as leader by peers.
4. Advanced knowledge of the Healthcare System and of the research procedures as well as the ICH guidelines, GCP and other ethical guidelines relevant to the pharmaceutical industry.
5. Advanced knowledge of clinical medicine, disease management, and medical research in at least one therapeutic area.
6. Ability to synthesize complex scientific information and analyze it within strategic and regulatory settings.
7. Proven ability to use IT tools and interface effectively with a variety of technical platforms.
8. Strong personal integrity, and customer focus.
9. Excellent interpersonal communication, negotiation and advanced presentation skills.
10. Prior experience in coordinating/leading multifunctional teams, projects and initiatives.
11. Must be able to adapt, organize, prioritize, and work effectively in a constantly changing field-based environment.

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Medical Science Liaison Rheumatology

Date Posted:
5/26/2017

Novartis

PA

Novartis is recruiting for a Medical Science Liaison to cover Central and Eastern PA, Southern NJ, and Delaware. Preferred location is Philadelphia.

A global healthcare leader, Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented, performance driven people. All of which makes us one of the most rewarding employers in our field. We're committed to peak performance, improving the quality of life, and embracing and leveraging diverse backgrounds, cultures and talents to achieve competitive advantage.

The MSL will serve as a liaison to the medical/scientific community and will be responsible for establishing, developing and maintaining relationships with prominent experts in the Rheumatology Therapeutic Area within the geographic area of coverage.

Major Accountabilities:

• The MSL will ensure the appropriate dissemination of clinical and scientific information regarding marketed and pipeline compounds in a timely, ethical and customer-focused manner.
• The MSL will implement medical strategies in collaboration with other Novartis colleagues for designated customers that include potential clinical trial site identification and support as well as review of investigator-initiated research protocols.
• The MSL will work to pair our key customer's educational and research needs with available Novartis resources and will provide the latest emerging data in response to specific healthcare professional inquiries.
• Comply with all credentialing requirements for any healthcare institution (e.g., hospital) which is part of the MSL call plan, including, among other things, routine background checks, medical testing (i.e., Tuberculosis test) or proof of immunizations, training on facility policies, and adherence to confidentiality and/or HIPPA agreements.
• The position requires approximately 60% travel.
The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.
Position will be filled at level commensurate with experience.

• Advanced Scientific degree or equivalent experience required. (PharmD, MD, DO, PhD, or DNP strongly preferred)
• Minimum of 2 years of Postdoctoral experience, or equivalent, in the pharmaceutical industry (preferred) or other healthcare environment to provide strategic and scientific/medical direction to national/regional business unit functions.
• Teaching experience is highly-desirable.
• Previous experience in the rheumatology, immunology space or related area is strongly preferred.
• Previous experience in a MSL Field Medical based position is also preferred.
• Thorough knowledge of medicine (including pharmacotherapy), treatment guidelines, clinical research processes, customer strategies, and FDA promotional guidelines, regulations, and ethical guidelines applied to the pharmaceutical industry is preferred.
• Excellent interpersonal communication and presentation skills are required.
• Ability to network and partner with important customers, including thought leaders, large group practices, medical directors, and pharmacy directors is required.
• Ability to travel (about 60%).
• Must be science oriented and be able to prioritize and work effectively in a constantly changing environment.
• Must have the ability to gain customer feedback, uncover business opportunities for Novartis and pair customer's unmet needs with available internal resources.
• Active membership in professional society(ies) is a plus.
• Working knowledge of Microsoft Office Suite (Word, PowerPoint, and Excel) and associated hardware is required.
• Must be a strong team player and effectively interface with other internal departments, including Corporate Customers, Regional Business Units, Marketing, Sales, New Product Commercialization, Medical Affairs, Research, and Business Analysis.

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Medical Science Liaison Cardiology

Date Posted:
5/26/2017

Novartis

NH

Novartis is recruiting for a Medical Science Liaison to cover Eastern Upstate NY, NH, VT, and ME. Preferred area of residence is eastern NY or NH.

A global healthcare leader, Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented, performance driven people. All of which makes us one of the most rewarding employers in our field. We're committed to peak performance, improving the quality of life, and embracing and leveraging diverse backgrounds, cultures and talents to achieve competitive advantage.

The MSL will serve as a liaison to the medical/scientific community and will be responsible for establishing, developing and maintaining relationships with prominent experts in the Cardiovascular Therapeutic Area within the geographic area of coverage.

Major Accountabilities:
• The MSL will ensure the appropriate dissemination of clinical and scientific information regarding marketed and pipeline compounds in a timely, ethical and customer-focused manner.
• The MSL will implement medical strategies in collaboration with other Novartis colleagues for designated customers that include potential clinical trial site identification and support as well as review of investigator-initiated research protocols.
• The MSL will work to pair our key customer's educational and research needs with available Novartis resources and will provide the latest emerging data in response to specific healthcare professional inquiries.
• Comply with all credentialing requirements for any healthcare institution (e.g., hospital) which is part of the MSL call plan, including, among other things, routine background checks, medical testing (i.e., Tuberculosis test) or proof of immunizations, training on facility policies, and adherence to confidentiality and/or HIPPA agreements.
• The position requires approximately 60% travel.

Keywords: MSL, medical science liaison, cardio, cardiology, cardiovascular, heart failure, kol, key opinion leader, investigator, cra, clinical research associate, patient enrollment, brand, drug, trial, American college clinical pharmacy
The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.
Position will be filled at level commensurate with experience.

• Advanced Scientific degree or equivalent experience required. (PharmD, MD, PhD, or DNP strongly preferred)
• Minimum of 2 years of Postdoctoral experience, or equivalent, in the pharmaceutical industry (preferred) or other healthcare environment to provide strategic and scientific/medical direction to national/regional business unit functions.
• Teaching experience is highly-desirable.
• Previous experience in the cardiology, cardiovascular space or related area is strongly preferred.
• Previous experience in a MSL Field Medical based position is also preferred.
• Hospital clinical experience or previous Pharma experience working with hospital-based products is highly desirable.
• Thorough knowledge of medicine (including pharmacotherapy), treatment guidelines, clinical research processes, customer strategies, and FDA promotional guidelines, regulations, and ethical guidelines applied to the pharmaceutical industry is preferred.
• Excellent interpersonal communication and presentation skills are required.
• Ability to network and partner with important customers, including thought leaders, large group practices, medical directors, and pharmacy directors is required.
• Ability to travel (about 60%).
• Must be science oriented and be able to prioritize and work effectively in a constantly changing environment.
• Must have the ability to gain customer feedback, uncover business opportunities for Novartis and pair customer's unmet needs with available internal resources.
• Active membership in professional society(ies) is a plus.
• Working knowledge of Microsoft Office Suite (Word, PowerPoint, and Excel) and associated hardware is required.
• Must be a strong team player and effectively interface with other internal departments, including Corporate Customers, Regional Business Units, Marketing, Sales, New Product Commercialization, Medical Affairs, Research, and Business Analysis.
• A valid US Driver’s License and a good driving record are required.

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Investigator Protein Sciences Group

Date Posted:
5/26/2017

Novartis

CA

At the Novartis Institutes for BioMedical Research (NIBR), the global research organization of Novartis, we are committed to discovering innovative medicines to cure diseases and improve human health. By hiring the best scientists, we have fostered an atmosphere for drug discovery where risk taking and innovation are rewarded. It is ultimately the talent of the individual that determines our success, while our state-of-the-art technologies and resources enable these ideas to be realized. The Infectious disease department at NIBR is a team of more than 200 scientists using a diverse array of approaches and cutting-edge technology to develop drugs to address unmet medical need.

Novartis is seeking a highly-motivated Ph.D. level scientist to join the Protein Sciences Group to support the development of our antibody discovery platforms. The successful individual will interact with multidisciplinary project teams focused on developing the next generation therapies for infectious disease and oncology.

This person will be responsible for leading a small group of scientists to support the advancement of antibody projects from early discovery to early development.
This position will require leading from the bench with growing management and supervisory responsibilities.

Responsibilities:
• Lead a group of scientists to provide expertise and support for antibody projects in different stages of the pipeline
• Utilize antibody development expertise to generate and develop tool and therapeutic antibodies
• Individually contribute to team goals, as well as achieve results through others
• Identify technical trends in the discipline and develop new scientific/technical processes or approaches, incorporating the latest scientific advances
• Support Novartis’ intellectual property objectives through timely and accurate filing of invention disclosures and patents
• Publish and present results, both internally and externally
• Work cross-functionally in a complex and fast pace research organization
• Identify and establish collaborations with other Novartis sites
• Manage, mentor, train, evaluate, and develop associates
The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.
The ideal candidate has:
• PhD in Biochemistry, Molecular/Cell Biology, Immunology or related discipline with a minimum of 4+ years of drug discovery experience in the biotechnology / pharmaceutical industry
• Expertise in phage and/or yeast display, hybridoma or B-cell cloning technology
• Experience in engineering and expression of monoclonal antibodies, Fabs, scFvs, bispecifics, as well as therapeutic proteins
• Experience characterizing and optimizing candidate therapeutic antibodies
• Proven track record of scientific accomplishments demonstrated by publications in high-impact journals
• Ability to adapt and rapidly integrate new technologies into existing projects

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Pharmacometrics PhD internship

Date Posted:
5/26/2017

Novartis

INT

Internship in Pharmacometrics for PhD students
PHARMA
Global Develop NPH
Switzerland
Basel
Novartis Pharma AG
Interns/Students on Novartis Payroll
Full Time
Internship
The internship will be focused on the development and applications of quantitative models to experimental data collected in drug projects. Data will quantify the influence of drug on pharmacological responses and/or patho-physiological processes and/or biological pathways. Mathematical, statistical, graphical or IT techniques will be applied for data analysis or even developed.

This internship will provide motivated students with an exposure to pharmaceutical industry and with the opportunity to learn in an exciting, multi-disciplinary and multi-cultural environment with leading scientists and domain experts. The duration is 3 months and can be extended depending on the topic. Location: Basel, Switzerland.
Currently enrolled at a university/FH as PhD student in Bioinformatics, Biomedical Sciences, Mathematics/Statistics or Pharmaceutical Sciences/Pharmacy. English Ideal candidate should have a good familiarity with quantitative methods and/or modeling in one-two domains among the following: mathematical, statistical, biological, pharmacological.
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Associate Scientist Drug Product Development

Date Posted:
5/26/2017

Novartis

INT

Associate Scientist Drug Product Development (m/f)
Novartis Technical Operations
NTO BTDM
Österreich
Austria Sandoz GmbH, Plant Schaftenau, Langkampfen
Research & Development
Vollzeit
Unbefristet
Sie bewerben sich, um Teil des Novartis Talent Pool zu sein. Wir sind derzeit nicht für diese Rolle rekrutieren, aber wir bauen eine Pipeline für zukünftige Chancen. Wenn Sie in Zukunft für eine ähnliche Position in Betracht gezogen werden möchten, dann reichen Sie bitte Ihren Lebenslauf ein.
• Evaluate and support implementation of new analytical technologies
• Prepare and review analytical reports
• Design, plan, perform, interpret and report scientific experiments for the analytical development of biopharmaceuticals
• Performing the development and characterization of robust manufacturing processes for the filling of syringes and vials according to Quality by design principles
• Producing pre-clinical trial supplies in our on-site pilot plant
• Supporting the transfer of the manufacturing processes to large- scale GMP facilities and supporting process validation, including the preparation of process risk assessments and attending production runs
• Generating scientific documents, supporting the generation of international registration documents
• Education: Master or PhD in pharmacy, biotechnology, biophysics, biochemistry or a similar education or MSc with at least 2 years’ of relevant experience
• Languages: fluent in English / German beneficial
• Experience: Ideally first experience in pharmaceutical development or manufacturing of finished dosage forms for biopharmaceuticals, Good knowledge in instrumental analytical techniques for recombinant proteins, e.g. HPLC, capillary electrophoresis and biophysical methods, analytical thinking and good presentation and technical writing skills, cGMP knowledge desirable

Our salary packages are competitive and take individual qualifications and experience into consideration. Moreover we offer attractive fringe benefits (e.g. profit sharing for all employees, modern company pension, childcare facility, training possibilities and global career opportunities). In accordance with the Austrian collective labour agreement, we advise you that the minimum gross annual salary for this role is 45.113,04 euros.

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Program Officer Immunology - Malaria

Date Posted:
5/26/2017

NIH

MD

Job Description: PATH is an international organization that drives transformative innovation to save lives and improve health, especially among women and children. We accelerate innovation across five platforms-vaccines, drugs, diagnostics, devices, and system and service innovations-that harness our entrepreneurial insight, scientific and public health expertise, and passion for health equity. By mobilizing partners around the world, we take innovation to scale, working alongside countries primarily in Africa and Asia to tackle their greatest health needs. Together, we deliver measurable results that disrupt the cycle of poor health. 
PATH seeks a Program Officer to join the Malaria Disease Area Research and Development Unit to manage a variety of research projects pertaining to vaccine development. The candidate should have a thorough understanding in immunology. Areas of particular interest are humoral immunity, immune correlates, monoclonal antibodies and antigen discovery.
Must have legal authorization to work in the United States. PATH is dedicated to building an inclusive workforce where diversity is valued. PATH is an equal opportunity employer. Every qualified applicant will be considered for employment. PATH does not discriminate based on race, color, religion, gender, gender identity or orientation, genetic information, age, national origin, marital status, disability status, political ideology, military or protected veteran status, or any other characteristic protected by applicable federal, state, or local law.
Job Location: Washington, District of Columbia, United States
Company Location: United States, Washington, D.C. 
Position Type: Full-Time/Regular

Job Duties:


Responsibilities include:

  • Plan, manage, and execute a wide range of activities in support of our lead identification and evaluation projects.
  • Provide scientific expertise to preclinical and clinical project teams.
  • Provide clear and concise data analyses and progress reports.
  • Prepare briefs and synthesize scientific literature. Provide analysis of key topics to project teams and leadership.
  • Plan, coordinate and manage internal and external project team meetings.
  • Manage internal documentation and reporting processes.
  • Contribute to the development of new research proposals.
  • Represent PATH at meetings with partners, funders, and the international malaria vaccine development community.
  • Stay current on research topics related to malaria and vaccine development by attending scientific conferences and conducting regular literature reviews.

 

Qualifications:

There is an opening for a Program Officer with a strong scientific background in immunology. Ideally the candidate should have postdoctoral experience, work well in a team and not be intimidated by a fast-paced high-load work environment. Experience in vaccine-related research is preferred. 

Required Skills:

  • Ability to understand, communicate, and present complex scientific concepts to a range of audiences, including staff, partners and donors.
  • Ability to perform in fast-paced, high-load work environment.
  • Strong interpersonal skills and ability to work collaboratively within multi-disciplinary team structure.
  • Ability to build and manage productive relationships with internal teams, partners, and donors.
  • Excellent problem solving and analytical skills.
  • Excellent written and oral communication skills.

Required Experience

  • MD, or PhD in Immunology, Molecular Biology, or related discipline and a minimum of three years of professional experience relevant to immunology and vaccine research; or equivalent combination of education and experience. 
  • Experience must include hands-on experience in the assessment of immune responses.
  • Experience in antibody immunology preferred.
  • Experience in infectious diseases preferred.
  • Experience in high-throughput sequencing technologies a plus.
  • Experience with clinical sample testing a plus.
  • Demonstrated success in achieving scientific goals as shown by first author publications in well-recognized peer reviewed journals.

 

 

To Apply:

Here is the link to the job description: http://bit.ly/2p5kdKd


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Postdoc HTS Antibody discovery

Date Posted:
5/26/2017

Kansas University

KS

Seeking to fill multiple postdoc positions to work on several projects in the laboratory which are funded by a 5-year NIH Early Independence Award that began in January 2017. Research applies high-throughput NGS and immune repertoire analysis techniques for rapid antibody discovery and to investigate the immune response to viral vaccines and natural infections.

 

Job Duties:

See job posting

Qualifications:

See job posting

Contact Info:

Brandon DeKosky, Ph.D.
Assistant Professor
Department of Chemical & Petroleum Engineering
Department of Pharmaceutical Chemistry
Kansas Vaccine Institute
The University of Kansas
2095 Simons Biosciences Research Labs, Rm 136B
Lawrence, KS 66044
dekosky@ku.edu 
http://www.dekoskylab.org

Special Volunteer, NIAID/VRC

To Apply:

Link to the job posting: https://employment.ku.edu/staff/8873BR


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Postdoc Epidemiology

Date Posted:
5/26/2017

NIEHS

NC

Postdoctoral Fellowship Position 

Position Description: The Social and Environmental Determinants of Health Equity group, led by Dr. Chandra Jackson, is seeking an experienced and well-qualified post-doctoral fellow. The group is part of the Epidemiology Branch in the Division of Intramural Research at NIEHS, NIH. The group investigates how physical and social environmental determinants of health influence racial, ethnic, and socioeconomic disparities in cardiometabolic health. In addition to identifying the biological mechanisms by which factors in the social and physical environments affect health and contribute to health inequities, this group is also interested in the translation of epidemiologic findings into interventions that address structural, macro-level as well as individual-level barriers to achieving and maintaining optimal health. Ongoing research addresses how physical and social attributes of neighborhood/housing and work environments affect, for example, insufficient sleep duration and inadequate sleep quality as well as subsequent cardiometabolic disease risk. 

Post-doctoral fellows in this group will have access to data from the National Health Interview Survey and cohorts such as the Multi-Ethnic Study of Atherosclerosis, Jackson Heart Study, Sister Study, Study of Environment, Lifestyle, and Fibroids, and the Agricultural Health Study. Using existing resources, fellows can develop their own research initiatives within the mission of the research group. 

Postdoctoral fellows within the Epidemiology Branch are encouraged to build on existing resources to develop new projects that become the basis for transition to independent awards. Initial appointments are two years with additional years possible depending on productivity and availability of funds. Fellows will be encouraged to take advantage of the rich and varied training and career development opportunities offered at NIEHS. The training environment is enhanced by proximity to the University of North Carolina Gillings School of Global Public Health where many of the Epidemiology Branch investigators have adjunct appointments. 

 

Job Duties:

See position description.

Qualifications:

Qualifications: Candidates with an earned doctoral degree in epidemiology or a closely related field or those with a medical degree and advanced graduate training in epidemiology, population health, or biostatistics within the past five years are invited to apply. Applicants must have extensive experience with epidemiologic or statistical data analysis. Preference will be given to candidates with demonstrated research interests in areas currently under investigation (e.g. health disparities; social determinants of health; sleep) in the research group and branch as well as to candidates with superior analytic and communication skills. 

To Apply:

To Apply: Applicants should submit the following materials to epifellowships@niehs.nih.gov: • Letter describing areas of research interest • Curriculum vitae with bibliography • Copies of 1-2 recent publications • Contact information for 3 individuals serving as references 

Application Deadline Date: Until filled. Position available immediately. The NIH is dedicated to building a diverse community in its training and employment programs.


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Postdoc Cell Cycle Dynamics

Date Posted:
5/26/2017

UNC-CH

NC

UNC Postdoc Opening: Cell Cycle Dynamics in Single Cells

The laboratory of Professor Jean Cook (UNC-CH Biochemistry & Biophysics) studies fundamental aspects of proliferation control with a long-term goal of understanding the organization of the human cell cycle, regulation of cell cycle transitions, and mechanisms that ensure global genome stability. A postdoctoral position is available to join a collaborative project with the Purvis lab (UNC-CH Genetics) using quantitative live cell imaging to map and model cell cycle transitions. The project involves fluorescent reporter design and validation, genome engineering, microscopy, and (in collaboration) computational modeling. The team is diverse and collegial, and the principal investigator is committed to effective mentoring.

Job Duties:

For more information visit https://sites.google.com/site/cooklabgroup/home/. The lab routinely employs single cell approaches using live and fixed cell imaging, biochemical assays of protein-protein and protein-chromatin interactions, and molecular analyses of protein post-translational modification and stability. 

Qualifications:

Qualifications are a PhD in cell biology, molecular biology, biochemistry, or a related field. Successful applicants will have a track record of research productivity and good teamwork skills. Apply with CV, cover letter, and contact information for references at http://unc.peopleadmin.com/postings/115133 or navigate to “positions” at the Cook lab website.

To Apply:

Apply at: http://unc.peopleadmin.com/postings/115133 or navigate to “positions” at the Cook lab website


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Postdoc Anesthesiology

Date Posted:
5/26/2017

Duke

NC

Department: 
Department of Anesthesiology, Duke School of Medicine
Job Description: 

An opportunity exists to join our research group in neuroinflammation and cognitive outcomes (http://anesthesiology.duke.edu/?page_id=838077). We are interested in the mechanisms underlying postoperative neurocognitive disorders and strategies to modulate neuroinflammation and innate immunity.

Job Duties:

Presently we have active projects in:

• neuromodulation of cholinergic signaling to treat postoperative neurocognitive disorders: mechanisms of action and design of innovative therapies

• mechanisms and regulation of blood-brain barrier opening and microglial function after peripheral surgery: modeling, preclinical studies, and clinical studies

• acute pain signaling and resolution of neuroinflmmation: mechanisms and innovations to increase therapeutic efficacy

 

Qualifications:

Requirements: 

We seek a highly-motivated individual who enjoys the freedom to pursue their own ideas in a supportive environment to join our team. A PhD degree is required with training in neuroscience, immunology, biochemistry, molecular biology, pharmacology, and/or a related field. Experience with mouse models, biochemistry/molecular biology, and immune-histology is required. The candidate will work in a strong interdisciplinary and collaborative environment at Duke University and Duke Medical Center.

To Apply:

How to Apply: 

For consideration submit a CV and the names and contact information of three professional references as a .pdf file attachment to:

Niccolo Terrando, Ph.D.

Assistant Professor of Anesthesiology

niccolo.terrando@duke.edu(link sends e-mail)

Contact Name: 
Niccolo Terrando
Contact Email: 
niccolo.terrando@duke.edu
Deadline to Apply: 

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Postdoc Cancer Immunotherapy

Date Posted:
5/26/2017

Columbia University Medical Center

NY

Description:

Post-doctoral fellow positions in cancer immunology and immunotherapy are available at the Columbia Center for Translational Immunology (CCTI), Columbia University Medical Center (CUMC), New York, NY The candidates will work on basic and translational tumor immunology with focus on T cell biology and adoptive immunotherapy of cancer and viral diseases with the goal of developing new treatments for patients. The lab concentrates on various aspects of anti-tumor responses mediated by antigen-specific CD4+ T cells including Th polarization states (e.g. Th1, Th17), memory formation, self-renewal, senescence and bioenergetics.

Job Duties:

The candidates will need to utilize molecular biology techniques to improve the activity of immune cells and to investigate underlying mechanism using realistic animal models and parallel translation into the novel clinical trials of adoptive immunotherapy for cancer, leukemia and refractory infections. The candidates will be expected to develop and execute independent research plans that lead to peer-reviewed publications, to work cooperatively within an interdisciplinary group of research personnel and to demonstrate excellent oral and written communication skills. Positions will open in July 2017.

Qualifications:

Requirements: 1. Ph.D. or equivalent doctoral degree (M.D., D.V.M., etc.) 2. Expertise/interest in molecular and cellular biology techniques, genetic engineering, systems biology and bioenergetics, virology, stem cell biology, immunology and animal studies 3. Interest in applying this interdisciplinary knowledge to tumor immunology, immunotherapy and T helper cell biology at the basic and translational level

To Apply:

Please e-mail your curriculum vitae, contact information and references to Dr. Pawel Muranski: muranskp@mail.nih.gov


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Immunology Faculty positions

Date Posted:
5/26/2017

Cleveland Clinic

OH

a) The Departments of Immunology and Rheumatic and Immunologic Diseases of the Cleveland Clinic are recruiting for 1-2 faculty positions at all academic levels to establish a translational research program investigating mechanisms underlying the development and progression of systemic rheumatologic diseases.

b) The Department of Immunology in the Lerner Research Institute of the Cleveland Clinic is recruiting for 1-2 faculty positions at the Assistant Professor level to establish research programs investigating innate and adaptive immune mechanisms in infectious diseases.

The high patient volume and clinical expertise of the Department has generated a robust biorepository of blood and other patient tissue samples that is coupled with clinical and laboratory patient data from the extensive patient populations seen for the many rheumatologic specialties of the physicians.  The availability of patients and samples combined with state-of-the-art immune analysis facilities in the Department of Immunology will provide unique resources for the development of this dynamic translational program.

The Department of Immunology consists of a dozen investigators with established programs in innate immune receptor signaling, B cell signaling and biology, transplant immunology, cancer immunology, and T cell-mediated autoimmune disease. The Department provides an extremely supportive environment for career and research program development, including state-of-the-art immune analysis facilities. The Department is located within the Lerner Research Institute, an integrated research community performing investigations in basic, translational, and clinical research, which ranks as the fifth-largest research institute in the country. In addition, the high patient volume and clinical expertise of the Cleveland Clinic coupled with clinical and laboratory patient data from the extensive patient populations served by the Clinic offers unique resources for the development of dynamic translational research programs.

 

Job Duties:

a) It is expected that the investigator will continue their ongoing research programs within the Department of Immunology at the Lerner Research Institute and develop a collaborative translational program with the physicians within the Department of Rheumatic and Immunologic Diseases.

b)  It is expected that the investigator will develop a strong and well-funded basic research program that includes translational interactions with clinical departments within the Cleveland Clinic.

Qualifications:

The ideal candidate will be a PhD, MD, or equivalent degree scientist with an established research program in immunology or inflammation related to systemic rheumatic disease. Such a program might include, but is not limited to: investigation into effector and/or regulatory mechanisms in autoimmunity or inflammation, the impact of the microbiota on the immune response, identification of novel biomarkers and more precise therapeutic targets, and/or the generation and/or impact of antibodies on vascular function. The successful candidate will have an established record of significant publications in the field and ability to procure funding support for their research program. Generous start-up and substantial resources will be made available to promote the success of this new program at the Cleveland Clinic.

To Apply:

Interested individuals should send a Cover Letter briefly detailing their program, major accomplishments, and plans to:

Robert Fairchild, PhD

Chair of Search Committee

Department of Immunology

NB3-59, Cleveland Clinic

9500 Euclid Avenue

Cleveland, OH 44195

 

fairchr@ccf.org

216-444-3146


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Postdoc Rheumatology

Date Posted:
5/26/2017

Johns Hopkins

MD

The laboratory of Dr. Felipe Andrade at Johns Hopkins University School of Medicine is seeking highly motivated and innovative post-doctoral scientists interested in the study of mechanisms in autoimmune rheumatic diseases. The main focus of this lab is the pathogenesis of rheumatoid arthritis (RA), an autoimmune disease characterized by the appearance of unique antibodies that target citrullinated proteins. Our work uses integrative approaches by applying experimental immunology, molecular biology techniques, and proteomics to the study of patient samples. The overarching goal of the lab is to elucidate mechanisms that drive and dysregulate protein citrullination in patients with RA. In particular, we have identified host (complement and perforin) and bacterial-mediated membranolytic pathways that drive neutrophil cell death as key principles in the abnormal production of citrullinated autoantigens in this disease (Sci Transl Med 2013, 5:209ra150; Sci Transl Med 2016, 8:369ra176; Front Immunol 2016, 7:461). Our studies have also focused attention on the oral pathogen Aggregatibacter actinomycetemcomitans as a potential pathogenic link between periodontal disease, citrullination and RA (Sci Transl Med 2016, 8:369ra176). How host and bacterial membranolytic pathways dysregulate citrullination in patients and can be inhibited in RA is a current priority of this lab.

The Johns Hopkins Division of Rheumatology is ranked #1 in the US by World and News Report in the last 9 years.

Job Duties:

Post-doctoral scientists interested in studying pathogenic mechanisms in rheumatoid arthritis.

Qualifications:

Highly motivated applicants with a PhD or MD degree and significant experience in molecular and cellular biology, immunology or microbiology may apply. 

To Apply:

Applications should be sent directly to Dr. Felipe Andrade (andrade@jhmi.edu), including curriculum vitae and names and contact information of three references. All applications will be considered until the position is filled. The Johns Hopkins University is an Affirmative Action/Equal Opportunity Employer. Salary will be commensurate with level of experience according to the scale of the National Institutes of Health.


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Postdoctoral Fellow Epigenetics Archer Lab

Date Posted:
5/26/2017

NIEHS

NC

EPIGENETIC MECHANISMS AND TRANSCRIPTIONAL REGULATION

Position Description:
Postdoctoral fellowships are available in Trevor Archer’s laboratory at the National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH) in North Carolina.http://www.niehs.nih.gov/research/atniehs/labs/escbl/pi/cge/index.cfm

Recent examples of our work can be found at the following links:http://www.ncbi.nlm.nih.gov/pubmed/26055322 http://www.ncbi.nlm.nih.gov/pubmed/26119756 and within the attached link;http://www.ncbi.nlm.nih.gov/pubmed/?term=archer+tk Successful candidates will have a choice of several exciting projects in the areas of Transcription, Epigenetics, and Stem Cell Biology. 

Location:
NIEHS main campus is located in the Research Triangle Park (RTP), North Carolina. The RTP is the largest research park in US located between Raleigh, Durham, and Chapel Hill, and is ~15 minute drive from Duke University, University of North Carolina-Chapel Hill, and North Carolina State University.

Salary/Benefits:
Successful candidates will be offered competitive stipend/salary commensurate with number of years of postdoctoral experience and accomplishments.

 

Job Duties:

We are seeking fellows with an interest in the mechanisms by which chromatin remodelers function with transcription factors to regulate signal transduction by nuclear receptors in cancer cells and with master regulators in embryonic stem cells.

Qualifications:

Qualifications:
Candidates should have obtained a PhD degree within the last 5 years in Biological Sciences and have extensive training in biochemistry and/or molecular biology and/or genetics; experience in stem cell biology and or bioinformatics, are also highly desirable but not essential. Excellent communications skills and a strong work ethic are essential.

To Apply:

To Apply:
Please send CV and the names of three references via email to
Trevor Archer, Ph.D.
Chief, Epigenetics and Stem Cell Biology Laboratory
Senior Investigator & Chief, Chromatin and Gene Expression Section
National Institute of Environmental Health Sciences
National Institutes of Health
Mail Drop C4-01
Research Triangle Park, NC 27709
Email: archer1@niehs.nih.gov

The NIH is dedicated to building a diverse community in its training and employment programs.


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Staff Scientist Molecular Neuroscience

Date Posted:
5/26/2017

NIMH

MD

Position Description:
The National Institute of Mental Health (NIMH), a major research component of the National Institutes of Health (NIH), and the Department of Health and Human Services (DHHS), is seeking exceptional candidates for a Staff Scientist position in the Intramural Research Program (IRP), Section on Molecular Neuroscience, Laboratory of Cellular and Molecular Regulation. This laboratory explores cyclic AMP signaling at the post-synapse in neurons of the ventral striatum and hippocampus in the mouse.

Qualifications:
Candidates must have a Ph.D. in Molecular Biology, Neuroscience, or a related discipline; experience in light microscopy including histochemistry and in vivo imaging of dendritic spines; synaptic neurochemistry including in vivo immediate early gene imaging; familiarity with rodent behavioral paradigms for learning, memory and addiction; neuroanatomy of reward systems; generation of transgenic and knockout mice using CRISPR and and TRAP-Cre technology; and stereotaxic surgery for tract-tracing and AAV expression in rodents.

Responsibilities:
The Staff Scientist's primary responsibilities will include surgical preparation of mice for in vivo imaging; in vivo using two-photon microscopy; behavioral analysis of genetically altered mice; morphometric analysis of spine dynamics using current high-throughput image analysis techniques. Salary will be commensurate with education and experience.

To Apply:
Applicants should send curriculum vitae and three letters of recommendation to Lee E. Eiden, Chief, Section on Molecular Neuroscience, 301-8225-6255, eidenl@mail.nih.gov.


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Staff Scientist Genetics

Date Posted:
5/26/2017

NHGRI

MD

Position Description:
As a Staff Scientist in the Section of Molecular Neurogenetics he/she will be responsible for the projects in the laboratory related to induced pluripotent stem cells (iPSC). The Staff Scientist will work to generate and characterize macrophages and neurons from patient- derived iPSCs. These models are essential for our studies of Gaucher disease and parkinsonism and will yield important insights regarding the pathogenesis of Parkinson disease. The Staff Scientist will study autophagy and inflammation in Gaucher disease. The Staff Scientist will use these cell models to validate new small molecule drugs identified though our collaborations with NCAT. These studies will impact the treatment of Gaucher disease and potentially Parkinson disease.

Requirements:

  • PhD
  • 5 years Postdoctoral training in cell biology
  • Experience working with macrophages and microglia
  • Extensive experience in generating and evaluating induced pluripotent stem cells (iPSCs) and iPSC-derived neurons and macrophages
  • Experience with confocal microscopy and flow cytometry
  • Experience in mentoring trainees
  • Extensive publication record

To Apply:
Please submit an application package including a CV and three refernces to Dr. Ellen Sidransky, sidranse@mail.nih.gov


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Staff Scientist Neural Gene Expression

Date Posted:
5/26/2017

NIMH

MD

Position Description:
The National Institute of Mental Health (NIMH), a major research component of the National Institutes of Health (NIH), and the Department of Health and Human Services (DHHS), is seeking exceptional candidates for a Staff Scientist position in the Intramural Research Program (IRP), Section on Neural Gene Expression. The laboratory uses a variety of techniques, including anatomical, molecular biological, transgenic animals, optogenetics, and electrophysiology to explore social behaviors in the mouse, especially as related to the CA2 area of the hippocampus.

Qualifications:
Candidates must have a Ph.D. or M.D with expertise in neuroscience; post-doctoral experience in rodent behavior, electrophysiology and multi-neuronal activity recording via calcium signaling using microendoscopy in freely-moving and behaving mice; and strong practical experience with computer programming, rodent surgery, preparation of animal study protocols, and student and fellow mentoring.

Responsibilities:
The Staff Scientist's primary responsibilities will include exploring the role of the hippocampal CA2 area in social behavior while instructing post-doctoral and post-baccalaureate fellows, maintaining up-to-date surgical and behavioral suites' functioning, supervising the large mouse colony, and presenting the laboratory's research in publications and at meetings. Salary will be commensurate with education and experience.

To Apply:
Applicants should send curriculum vitae and three letters of recommendation to W. Scott Young, 49 Convent Drive, Building 49/5A56, Bethesda, MD 20892, 301-496-8767, wsy@mail.nih.govApplications should be submitted by June 26, 2017.


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Scientist/Research Associate

Date Posted:
5/26/2017

Wellstat

MD

Position Description:
Wellstat, a privately-held biotech company located in Rockville, MD, is seeking a Scientist or Research Associate to join our team.

The candidate will be responsible for recombinant protein purification from mammalian cell culture by chromatographic processes using GE's AKTA system and Unicorn Operation Software. In collaboration with other groups, the candidate will also be responsible for recombinant protein characterization, stability, and formulation studies. The candidate will be responsible for developing protein purification processes that can be scaled-up in a GMP facility.

Qualifications:
The candidate must have hands-on experience and in-depth knowledge in recombinant protein purification from mammalian cells. The candidate must have proven expertise in operating GE's AKTA protein purification system and its Unicorn Operation Software. The candidate should possess strong background in protein chemistry. The candidate should have strong problem-solving skills. The candidate should be familiar with GLP and GMP working environment. The candidate should be able to independently design and perform a research project and analyze the data and make appropriate conclusions. The candidate should be a team player and have good communication skills. The candidate should have a Ph.D. or a Master degree in a relevant field and have more than three years experience in recombinant protein purification.

Wellstat is an equal opportunity employer and offers a competitive salary and comprehensive benefits package.

To Apply:
Please send CV to: Wellstat, 14200 Shady Grove Road, Suite 600, Rockville, MD 20850, Attn: HR-WIT-01 or Submit your CV torecruiting@wellstat.com


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Associate Scientist/Scientist I

Date Posted:
5/26/2017

Neon Therapeutics

MA

Position Summary

 

Neon is seeking a highly-motivated Scientist to join the Peptide Chemistry Department. The candidate will work within the Analytical Chemistry group and in close collaboration with Peptide Synthesis and other groups at Neon on programs that aim to develop novel personalized neoantigen based cancer vaccines. He/she will work independtly as well as part of a multi-disciplinary research team to purify and analyze peptides.

 

 

 

Job responsibilities include:

 

Perform automated, mass-directed high throughput purification of peptides and peptide libraries at different scales using HPLC-MS systems

Develop analysis and purification methods and protocols

Develop automated analysis and purification processes

Implement LIMS in analysis, purification and compound registration

Perform downstream HPLC fraction work up, including fraction analysis, pooling and lyophilization

Analyze crude samples, HPLC fractions, and final products using UPLC-MS

Maintain analytical and purification instruments

Organize final products and QC data for compound registration

Work productively in a team environment and independently and deliver against timelines.

 

 

Experience and essential skills:

 

A Ph.D. with more than 1 year industry experience, M.S. with more than 3 years of industry experience or B.S. with more than 5 years of experience in purification and analysis

Comprehensive knowledge and technical expertise in chromatographic separation and HPLC analysis

Strong experience in mass-directed purification with automated LC-MS systems

Hands on experience in HPLC trouble shooting and maintenance

Experience with UPLC-MS systems

Experience in using Masslynx and Empower software

Experience with automation and LIMS system is highly desirable

Excellent interpersonal and communication skills and a pro-active mentality

Highly organized with strong attention to details

Must be able to work in a team and collaborative environment


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U.S. Life Sciences Specialist

Date Posted:
5/22/2017

L.E.K.

MA

L.E.K. Life Sciences Specialists (LSS) are ambitious and bright PhDs / MDs that are focused in a science field and are from the top programs at leading universities. Working alongside senior and junior members of the case team, LSSs apply their unique skills and experiences to projects while receiving top training in strategic business consulting. Each person will take on responsibility for leading modules of project work and driving analytical insights to support L.E.K.’s deepest vertical.

As an LSS, you gain comprehensive training that integrates science, business and economics to prepare you for strategic leadership in the healthcare and life sciences industry. You will not only be a technical expert, but also a business expert, developing cutting-edge strategic and managerial skills that provide a strong foundation for a career at L.E.K.

LSSs work collaboratively with peers and senior leadership to define initial hypotheses, direct and control research and analytical work, and produce fact-based and analytically robust conclusions.

While casework needs will vary every day, your role will involve:

  • Conducting primary and secondary research on markets, competitors and customers
  • Applying your technical and scientific expertise to client issues
  • Performing rigorous analysis to pinpoint appropriate, practical recommendations for your clients
  • For Advanced Degree candidates, L.E.K. offers the opportunity to build on your academic foundation and follow a fast track to the role of Consultant.
  • Collaborating with team members to transform research and analysis into thoughtful  insights and communicating key findings to the client in written presentations  and verbal interactions that deliver maximum impact to clients

Why L.E.K. is Different

The role of an L.E.K. Life Sciences Specialist is differentiated from the broader market for a number of reasons:

  • Meaningful Management Opportunities – LSSs will quickly gain responsibility for managing Associates and day-to-day core project leadership
  • Breadth of experience – L.E.K. projects span strategy, M&A and operations with a deep focus on strategy and Life Sciences as L.E.K.’s deepest vertical. LSSs will typically work on ~6-10 projects / year resulting in a stronger foundation across business skills with a breadth of industry exposure
  • International Experience – Approximately one-third of L.E.K projects involve an international component, which allows LSSs to work on international case teams or, if they choose, to relocate to international offices on a short term basis.
  • Upward Mobility – L.E.K. is a meritocracy with a young, entrepreneurial culture. Promotion paths do not follow a strict timeline; we promote people as fast as they develop.
  • Fun, Stimulating Work Environment – There is a greater sense of camaraderie in offices given that L.E.K. teams spend substantially more time in their home office relative to teams at peer firms.

Qualifications and Experience Needed

L.E.K. seeks highly motivated, creative, and entrepreneurial candidates who possess outstanding academic achievement, comfort with quantitative analysis, significant professional experiences, notable extracurricular interests, and demonstrated leadership and initiative.

L.E.K Consulting is an Equal Opportunity Employer

Please note the starting date for this position is October 2, 2017

You can expect to hear back about the status of your application at the beginning of June.

Apply at https://lek.tal.net/vx/lang-en-GB/mobile-0/appcentre-2/brand-5/candidate/so/pm/1/pl/6/opp/1183-U-S-Life-Sciences-Specialist-October-2017/en-GB 


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Technical Director/MRI Scientist

Date Posted:
5/21/2017

Childrens National Medical Center

DC

Position Description:
We are seeking an exceptional research scientist to fill an Assistant Professor (or above) Technical Director Position. The successful applicant will join our multidisciplinary team of biomedical engineers, computer scientists, MRI physicists, neuroscientists, radiologists, neurologists, neonatologists, cardiologists, and nurses.

Qualifications:
Applicants for this position must have a Ph.D. in Bioengineering, Electrical Engineering, Physics, Computer Science or Related field, and a minimum of 5 years of experience in developing registration algorithms for the compensation of tissue motion and deformation of various anatomical structures, including the brain, placenta and heart. The successful candidate will lead the development of biomedical image analysis processing tools for fetal/neonatal diagnostic imaging and interventional image guidance. The work will be centered around real-time imaging and reconstruction methods with a focus on well-engineered solutions that can be developed, tested and implemented in a clinical setting to image the fetus and newborn infant. The MRI staff scientist will be responsible for conducting independent research in the field of biomedical image analysis, support clinical projects and supervise undergraduate, graduate and postgraduate trainees.
We are looking for a candidate with strong communication skills, who will work well with our diverse, dynamic group; aggressively pursue research; and publish at a high rate.

To Apply:
Applicants should send a brief statement of research interests, their curriculum vitae and contact information for at least three references to Dr. C. Limperopoulos: climpero@childrensnational.org

Applications and requests for further information should be sent to:
Catherine Limperopoulos, PhD
Director, The Developing Brain Research Program
Vice Chief of Research, Division of Diagnostic Imaging and Radiology
Co-Director of Research, Division of Neonatology
Children's National Health System
George Washington University School of Medicine and Health Sciences
climpero@childrensnational.org


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Scientific Program Manager

Date Posted:
5/21/2017

Cherokee Nation Technology Solutions

DC

Position Description:
Our client, the Armed Forces Health Surveillance Branch (AFHSB), strives to be the central epidemiologic resource and a global health surveillance proponent for the U.S. Armed Forces. The AFHSB provides timely, relevant, actionable, and comprehensive infectious disease surveillance information to promote, maintain, and enhance the health of military and military-associated populations.

We are seeking a program manager with a public health/epidemiology background to provide program management support for the Global Emerging Infections Surveillance Section (GEIS) of AFHSB. The incumbent will support the client by providing GEIS program coordination and oversight services to ensure smooth operations of the GEIS program in its mission to enhance force health protection. Successful candidates will have strong program management and organizational skills and experience working with U.S. government agencies such as the DoD.

Responsibilities:

  • Provide program management leadership to accomplish long-range goals and short-term objectives for the GEIS program office and the GEIS network and ensure excellence in strategic, financial, operational, tactical and organizational functions of the GEIS program;
  • Provide GEIS program coordination and oversight services to ensure smooth operations of the GEIS program, including task management, establishing timelines and milestones, and tracking deliverables;
  • Provide key support to identifying and defining process, outcome variables, and metrics, including return on investment, to assess success and failure of GEIS-funded surveillance efforts and initiatives;
  • Support the development of publications, presentations, and timely information products based on GEIS-funded surveillance for DoD leaders and other stakeholder, in support of force health protection;
  • Provide guidance on best practices for proposal management;
  • Support the review and prioritization of programmatic/focus area-specific strategies, programs, projects, and proposals to ensure alignment with overarching GEIS strategic direction, and provide recommendations on enhanced alignment and opportunities to address critical organizational gaps;
  • Provide scientific/technical input for GEIS on infectious disease surveillance projects and programs across the GEIS Focus Areas as needed;
  • Perform other duties as needed.

Qualifications:

  • Graduate degree in Public Heath, Epidemiology, Biostatistics, Microbiology, Molecular Biology, or related field required; doctoral degree (PhD, MD, DO, DVM, DrPH, or related degree) preferred; minimum 8 years of experience in laboratory, research, or public health setting required;
  • Program management experience and experience in proposal management required;
  • Experience managing projects and staff to ensure timely delivery of high quality products to the government client;
  • Experience in designing or maintaining relational databases preferred;
  • Analytical and organizational skills to synthesize data into informational reports to support program evaluation;
  • Excellent organizational skills and strong oral and written communication skills;
  • Ability to collaborate with other professionals;
  • Demonstrated experience supporting Federal clients, particularly DoD, preferred;
  • Active Secret clearance preferred; applicants selected will be subject to a U.S. Government security investigation and must meet eligibility requirements for Secret clearance.

To Apply:
Please vitsit this website to apply online.

Cherokee Nation Technology Solutions (CNTS) provides technical support services and project support personnel to its defense and civilian agency clients. CNTS specializes in locating hard to find candidates for rapid response requests throughout the country. It provides a tailored management approach for complex government programs and disciplines including information technology, science, engineering, construction, research & development, facilities management, program management, and mission support. Wholly owned by the Cherokee Nation, CNTS is part of the Cherokee Nation Businesses family of companies.

We are an equal opportunity/affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, protected Veteran status, gender identity and sexual orientation.


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Postdoctoral to Faculty Transition Program Molecular Medicine

Date Posted:
5/21/2017

University of Toledo College

OH

Position Description:
The University of Toledo College of Medicine and Life Sciences (UTCOMLS) is launching an innovative program designed to accelerate the transition of postdoctoral fellows to extramurally-funded, tenure-track UTCOMLS faculty. Several postdoctoral positions are available for individuals of an ambitious mindset, who come prepared with innovative ideas for NIH-level funding. Candidates must also have the ability to develop and test hypotheses independently, work in a collaborative environment and possess excellent communication skills both in written and oral presentations. The program is for 2 years with an opportunity to extend to a third year.
Candidates will have competitive opportunities to transition into faculty tracks within the various Departments of UTCOMLS. Besides merit, a key factor for recruitment will be the candidates' long-term commitment to stay as faculty members at our Institution.

Qualifications:
Candidates must have a PhD or MD degree with significant laboratory research experience preferably in physiology, genetics & genomics, endocrinology, or cell and molecular biology. The ideal candidate should have interests relevant to whole-animal or human physiological systems, preferably in the areas of cardiovascular, renal, endocrine or metabolic diseases, possibly including biomarkers, genetics, or the impact of the microbiome on those systems.
For potential mentor match, candidates should become familiar with the strengths of the Departments of Medicine and Physiology & Pharmacology, which include: THe Microbiome Consortium, THe Center for Hypertension and Personalized Medicine, and the Center for Diabetes and Endocrine Research.

To Apply:
Please send your CV and list of references via email to: Professor Bina Joe (bina.joe@utoledo.edu) and Professor Lance Dworkin (lance.dworkin@utoldeo.edu).


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Clinical Trials Results Analyst

Date Posted:
5/21/2017

ICF Intenational

MD

Position Description:
The Health, Research, Informatics, and Technology (HRIT) Division seeks a ClinicalTrials.gov Results Analyst to support our National Institutes of Health/National Library of Medicine (NIH/NLM) client. ClinicalTrials.gov is a registry and results database of publicly and privately supported clinical research conducted in the United States and around the world. Both registration and results submission are accomplished through the Web-based Protocol Registration and Results System (PRS). Responsible parties commonly register trials and submit results prior to a journal publication. Unlike journal articles that are reviewed by both scientific colleagues and editors, data submitted to ClinicalTrials.gov are not peer-reviewed prior to posting, however specific review criteria must be met. Information regarding the ClinicalTrials.gov database and reporting requirements can be found athttp://clinicaltrials.gov/ct2/manage-recs/fdaaa

Key Responsibilities:

  • Perform quality assurance/quality control reviews of clinical trial results submissions for consistency with review criteria
  • Clearly communicate (via record reviews, teleconferences, emails, workshops, etc.) with "responsible parties" (e.g., clinical trial sponsors, principal investigators, statisticians, etc.) to facilitate understanding of and adherence to submission requirements
  • Gain a working knowledge of the ClinicalTrials.gov Basic Results Data Element Definitions (http://prsinfo.clinicaltrials.gov/results_definitions.html) and ClinicalTrials.gov results review criteria (http://prsinfo.clinicaltrials.gov/ResultsDetailedReviewItems.pdf)
  • Create new documentation to help responsible parties submit their clinical trial results records
  • Devise and help implement strategies to improve the quality of submissions.
  • Participate in weekly team meetings with NLM staff to discuss process improvement
  • Perform general editorial proofreading

Basic Qualifications:

  • PhD from an accredited college in a biomedical science and/or mathematics-related discipline (epidemiology, biostatistics, neuroscience, pharmacology, biochemistry, etc.)
  • Strong critical thinking, analysis, and problem-solving skills
  • Experience with standard mathematical concepts and statistics (correlations, trends, significance, etc.)
  • Experience with standard quantitative measures for health studies

Preferred Skills/Experience:

  • Background knowledge relevant to understanding and interpreting clinical trial data and statistics
  • Experience with analysis and reporting of clinical trial data
  • Ability to critically appraise clinical trial design and methodology and to identify internal inconsistencies in clinical trial data reporting
  • Experience (via coursework and/or job duties) working with and interpreting the following concepts:
  1. Mean, median, least square mean, standard deviation, range, inter-quartile range, confidence intervals, etc.
  2. Frequency, incidence, proportion, percentage, rate, etc.
  3. Time-to-event measures
  4. Parametric and non-parametric statistical tests, interpretation of p-values

Professional Skills:

  • Ability to work within a team environment and contribute to consensus-based decision making
  • Ability to identify, analyze, and solve problems creatively and independently
  • Ability to handle multiple tasks simultaneously and shift priorities as directed
  • Ability to work efficiently with team members in a fast-paced environment
  • Excellent oral and written communication skills
  • Excellent interpersonal skills and ability to work with people at every level
  • General computer skills

To Apply:
Please go to icfi.com/careers, click on "Apply Now" and use search phrase "Clinical Trials Results Analyst" or Job Number: 1700001534


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Scientific Annotator Multifactorial Disease Biology

Date Posted:
5/21/2017

Mindspec

VA

Position Description:
We are seeking talented and motivated individuals interested in working in a multi-disciplinary team. The positions offer an opportunity to work in the rapidly evolving area of multi-factorial disease biology in a flexible, dynamic research environment.
MindSpec, Inc. (http://www.mindspec.org/), is a nonprofit research organization that studies molecular causes of neurodevelopmental disorders such as autism using an integrated bioinformatics approach. MindSpec created the first genetic database for autism (AutDB), which is licensed to the Simons Foundation as SFARI Gene (https://gene.sfari.org/).

Qualifications:
Applicants must have an M.S. degree or higher in Genetics/Molecular Biology/Neurobiology or a related field with a strong knowledge of animal models of human disease. Applicants should also have excellent written and oral communication skills. Candidates who have research experience with zebrafish (Danio rerio) or Drosophila melanogaster are encouraged to apply.

Responsibilities:

  • Assess peer-reviewed scientific publications to determine their suitability in the context of given inclusion criteria.
  • Read and extract data from peer-reviewed scientific publications.
  • Use, evaluate and provide direction to develop data models and standards.
  • Take part in weekly meetings to help promote interpretative consistency between team members.

To Apply:
Please send cover letter and curriculum vitae to job@mindspec.org.


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Scientist I RAS

Date Posted:
5/21/2017

Leidos

MD

Program Description:
The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish National Cancer Institute (NCI) research objectives. The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community. A major focus of the CRTP is the NCI RAS Initiative with the goal to discover new therapeutic interventions against RAS-driven cancers. 
 
Position Description:
The Scientist I will work in support of the Frederick National Laboratory/NCI RAS Initiative in Frederick, Maryland.  One of the major objectives of the RAS initiative at the Frederick National Lab for Cancer Research (FNLCR) is to dissect the biology and mechanisms that result in oncogenic signaling KRAS mutant cells in support of drug discovery efforts. The Scientist I using primarily 3D cell culture systems will: 1) work to expand knowledge of RAS signaling pathways, 2) participate in experimental design and to independently conduct experiments in a priority-driven environment, 3) complete projects independently and as part of a team, 4) be responsible for timely updates of the project progress to their supervisor both informally and by formal report writing, 5) generate high-quality peer-reviewed publications, 6) be responsible for formal reporting of data including presentations and/or publications and, and 7) stay abreast of current research techniques and remain knowledgeable in pertinent areas through reading literature and by attending scientific presentations.  

To learn more about the RAS Initiative at the Frederick National Lab, please visit: https://www.cancer.gov/research/key-initiatives/ras
For information regarding Dr. Rachel Bagni, Sr. Scientist, Cancer Research Technology Program, and her lab, please visit: https://www.cancer.gov/research/key-initiatives/ras/screens-assays/model-development.
 
PLEASE NOTE THAT LEIDOS BIOMEDICAL RESEARCH, INC. CANNOT HIRE J-1 VISA HOLDERS FROM THE NATIONAL INSTITUTES OF HEALTH.

Qualifications:
To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:

  • PhD in a field related to pharmaceutical science, medicinal chemistry, or chemistry, or in a related discipline from an accredited college or university according to the Council for Higher Education Accreditation (CHEA) appropriate to biomedical research, or eight (8) years of experience in lieu of degree
  • Foreign degrees must be evaluated for U.S. equivalency
  • No experience required beyond the educational requirement
  • Knowledge of cell biology and signal transduction pathways
  • Ability to perform basic molecular biology experiments both independently and as a part of the RAS team in pursuit of specific research goals and objectives
  • Knowledge and ability to generate and characterize engineered cell lines used to study oncogenic signaling
  • Cell culture and cell-based assay development experience
  • Must be able to obtain and maintain a Security Clearance

Preferred Qualifications:
Candidates with these desired skills will be given preferential consideration:

  • Background in oncology and experience with in vitro cancer cell models
  • Experience with 3D cell culture model systems and 3D cell-based assays
  • Familiarity with the relevant scientific literature
  • Ability to develop and modify methods and techniques independently

To Apply:
If interested, please apply on-line for position #635379 at http://jobs.leidos.com/ShowJob/Id/1122950/Scientist-RAS-3D-Cell-Culture-(NCI)/

For mor information about Leidos Biomed, please visit our webpage at www.leidosbiomed.com.


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Staff Scientist Neuroimaging

Date Posted:
5/21/2017

NIDA

MD

Position Description:
The National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), is recruiting for a Staff Scientist to conduct neuroimaging research within its Intramural Research Program (IRP) located in Baltimore, Maryland. The goal of this search is to identify a candidate who will enhance this collaborative environment within the Neuroimaging Research Branch (NRB).

Qualifications:
We are seeking a candidate who is committed to scientific excellence, and understands the intellectual benefits of collaborative research to conduct state-of-art research on fundamental mechanisms that underlie drug addiction and to develop strategies for the treatment of the disorder. Applicants must hold an MD, PhD or equivalent degree. Criteria for selection include solid training in neuroimaging technologies (functional MRI, structural MRI, magnetic resonance spectroscopy, etc.) and substantial experience in conducting research on neuroimaging of drug addiction in humans and preclinical models.

Duties:
The selected candidate will carry out the research within the Neuroimaging Research Branch, and will be responsible for setting up research protocols, conducting experiments on human participants and preclinical models, training new trainees (post-doctoral, pre-doctoral and post-bachelor fellows), as well as collaborating with other intramural and extramural research groups. Salary will be commensurate with experience.

To Apply:
The position is open to both U.S. and non-U.S. citizens. Interested candidates must submit a curriculum vita, bibliography, a one-page summary of research interests, and the names and contact information (work/email addresses, phone) of three references (via pdf or Microsoft word format only - paper applications will not be accepted) to: Yihong Yang, Senior Investigator, atyihongyang@mail.nih.gov

Review of applications will begin in late April 2017, and continue until the position is filled

The NIH encourages the application and nomination of qualified women, minorities and individuals with disabilities. The HHS and NIH are Equal Opportunity Employers.


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Medical Geneticst

Date Posted:
5/21/2017

Cleveland Clinic

OH

Position Description:
The Center for Personalized Genetic Healthcare, the clinical arm of the Geomic Medicine Institute, at the Cleveland Clinic is seeking a passionate, academic Medical Geneticist with an interest in general, cardiovascular, and/or prenatal genetics. CPGH is the home of all of medical genetics within the Cleveland Clinic Health System. The medical geneticist position will work with an outstanding group of experienced genetic counselors who are knowledgeable with the referral base, testing processes, and patient population, and who practice to the top of their license. The general genetic counselors have over 30 years of combined genetic counseling experience.

Duties:

  • Evaluate children and adults for suspected general genetic disorders.
  • Identify and assess patients with potential risk for heritable diseases.
  • Medical genetic oversight of prenatal genetics program.
  • Work with patients' primary care providers and other clinicians to incorporate the genetic assessment and management inot overall patient care plans.
  • Inpatient consults and after-hour call.

Qualifications:
We seek an individual who is interested in educating rotating medical students, genetic counseling students, and residents. Our position is flexible and could fit a pure clinician with an interest in clinical investigation or a physician-scientist.

To Apply:
Please submit a cover letter and current copy of your recent CV directly to Keith Cederlund, cederlk@ccf.org (216-210-5190)


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Scientific Program Manager

Date Posted:
5/21/2017

Ripple Effect Communication

MD

Position Description:
Ripple Effect seeks a Scientific Program Manager with extensive project management experience and knowledge of biospecimen science, to provide support to the Biorepositories and Biospecimen Research Branch of the Division of Cancer Treatment and Diagnosis. Through our partnership with the National Institutes of Health, Ripple Effect offers professionals the opportunity to work with one of the most prestigious research organizations in the world in one of three areas: communications and marketing, program and policy, or research and evaluation.

This is a long-term contract position at the NIH. The position offers:
- Competitive salary with comprehensive benefit package
- Opportunity to work at NIH, world's foremost medical research center

Duties:
The successful candidate shall:

  • Collaborate with staff on contract management activities associated with the Genotype-Tissue Expression (GTEx) project, an NIH Common Fund program.
  • Coordinate and design activities related to the development, approvals and launching of new research funding concepts that utilize government grant and contract funding mechanisms. Concept topics may include biospecimen science, biomarker assay development, biorepository operations, etc.
  • Coordinate and document projects from beginning to completion; monitor and report the status of completion, funding and results attained; provide progress reports.
  • Initiate and maintain communications with subcontractors and project collaborators.
  • Collect, analyze and interpret data and findings; prepare summaries, reports, presentations, and manuscripts based on analyses and results.
  • Coordinate the development of contractual statements of work (SOWs) among collaborating parties; monitor editing and approvals; format and produce final documents; pay close attention to organization, content, spelling and grammar.
  • Track and monitor timelines, milestones, requirements and deliverables for BBRB programs and contracts to ensure that objectives are met.
  • Track budget expenses and analyses; prepare report of invoicing and burn rates.
  • Participate in audits, trainings and site visits as needed.
  • Attend national and international scientific conferences to provide information on BBRB programs; present scientific reports; identify potential collaborators.
  • Perform research in support of strategic planning for BBRB's biospecimen science research programs.
  • Analyze the scientific merit and the adequacy of current and projected BBRB research programs.
  • Identify gaps in existing scientific knowledge and provide recommendations for future research efforts.
  • Report on the progress of BBRB Programs to senior management.
  • Review requests for proposals (RFPs) by reading and scoring RFPs and participating in Source Evaluation Group (SEG) meetings.
  • Prepare and/or contribute to manuscripts for publication.
  • Review scientific papers, reports and manuscripts prepared by others, prior to submission.
  • Plan work assignments for colleagues and team members.
  • Make recommendations on aspects of efficiency and continuous process improvement.
  • Advise upper level management in the area of enterprise resource planning, including effective use of human and financial resources.
  • Remain abreast of the literature in biospecimen science, biobanking and cancer diagnostics.
  • Advise upper level management on the latest published research, findings and trends in biospecimen science, biobanking and cancer diagnostics.
  • Organize and coordinate arrangements for meetings, web meetings, video conferences and teleconferences.
  • Prepare and distribute agendas, background materials, documents and meeting minutes; establish and maintain communications with participants.
  • Coordinate issues and follow up on team action items; ensure that day-to-day assignments are completed.
  • Work with team members to address action items and issues.

Requirements:
The candidate must have:

  • Ph.D. in a related discipline plus three (3) years of experience in the tasks listed above.
  • Minimum of five (5) years of experience in a healthcare, scientific, academic medical center, biotech industry or engineering environment.
  • Successful track record of managing large (million ) projects, with ability to handle projects in various stages.
  • Proven experience managing projects and developing written documents, including grants, manuscripts, etc. Strong knowledge of biospecimen science and biomarker assays preferred.
  • Knowledge of NIH/NCI guidelines preferred.
  • Understanding of and experience with standard business documentation (e. g., contract language).
  • Expertise in Microsoft Office Suite (MS Word, Excel, PowerPoint, Outlook).
  • Experience with document management through Microsoft SharePoint.
  • Experience using web meetings and teleconferences for meeting management.
  • Strong oral communications skills, including presentation skills, proven through past work experience.
  • Excellent overall writing and document preparation skills.
  • Excellent analytical, organizational and time management skills.
  • Ability to multi-task and pay close attention to detail.

To Apply:
For more information and to apply online, please click here.


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Professor Microbiome Research and Microbial Genetics

Date Posted:
5/16/2017

Jackson Labs

CT

Faculty Position in Microbiome Research and Microbial Genomics

Tracking Code
5801
Job Description

 

The Jackson Laboratory (JAX) is inviting applications for Assistant, Associate, and Full Professors to join in expanding a major program in Microbiome Research and Microbial Genomics. We are seeking individuals who are taking innovative approaches to understand the role of microbiotas in human health to join our culture of cooperation and program integration.

 

 

 

The JAX Microbiome and Microbial Genomics initiative involves both our Farmington, Connecticut and Bar Harbor, Maine campuses. JAX resources enable genetic, genomic, computational, molecular, cellular, organismal and systems approaches for microbiome research. These include:

 

 

 

  • The Genomics Technology Core to provide high throughput DNA sequencing
  • Computational Science and Information Technology Cores to provide analysis, visualization, and data management expertise
  • Biorepository and sample management expertise to handle large-scale acquisition of clinical samples
  • Microbiology facilities for isolation, culturing, and analysis of microorganisms
  • State of the art mouse genetic and veterinary facilities including a large repository of strains and mutants, expertise for microbiome and pathogen research, a germ-free/gnotobiotic facility, and an extensive phenotyping capability
  • Advanced genetic techniques such as CRISPR/Cas9 genome editing technologies for innovative approaches to investigating host-microbiome interactions

 

 

 

 

 

JAX is an independent, nonprofit biomedical research institution with a highly collaborative environment fostering multidisciplinary approaches to investigate complex biological questions. Faculty members are supported by outstanding scientific services, unparalleled mouse and genomic resources, postdoctoral and predoctoral training programs, and numerous courses and conferences.

 

Required Experience

 

Candidates must have a Ph.D., M.D. or D.V.M. degree, and 4-5 years of relevant postdoctoral training, with an exceptional record of research accomplishment, and the ability to develop a competitive, independently funded research program. Opportunities are available for shared mentorship of trainees, and integration with the three Jackson Laboratory campuses in Maine, Connecticut and California.

 

 

Applicants must apply online.  Please submit a curriculum vitae and a concise statement of research interests as one document, using the link below.  In addition, please have three letters of reference sent to: facultyjobs@jax.org.

Job Location
Farmington, Connecticut, United States
Position Type
Full-Time/Regular
 

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Professor Genomic Medicine

Date Posted:
5/16/2017

Jackson Labs

CT

Faculty Positions, The Jackson Laboratory for Genomic Medicine

Tracking Code
5800
Job Description

 

The Jackson Laboratory for Genomic Medicine in Farmington, Connecticut is inviting applications for Assistant, Associate, and Full Professors. The campus is dedicated to advancing precision medicine using genomic strategies to understand the complex functional networks underlying health and disease, and the development of novel diagnostics and therapeutics. We are seeking individuals to join our interactive culture of cooperation and program integration.  Areas for recruitment include:

 

  

 

  • Cell Biology
  • Cancer Immunology
  • Clinical Genetics
  • Human Population and Evolutionary Genetics
  • Microbial Genomics, Microbiome Research and Infectious Diseases
  • Computational Biology and Bioinformatics (particularly research programs in systems biology/interactome analysis)

 

 

 

 

 

The Jackson Laboratory offers a uniquely collaborative scientific research environment. Faculty members are supported by outstanding scientific services, unparalleled mouse and genomic resources, postdoctoral and predoctoral training programs, and numerous courses and conferences.

 

Required Experience

 

Candidates must have a Ph.D., M.D. or D.V.M. degree, and 4-5 years of relevant postdoctoral training, with an exceptional record of research accomplishment, and the ability to develop a competitive, independently funded research program. Opportunities are available for shared mentorship of trainees, and integration with the Jackson Laboratory campuses in Maine and California.

 

 

Applicants must apply online.  Please submit a curriculum vitae and a concise statement of research interests as one document to the link below.  In addition, please have three letters of reference sent to: facultyjobs@jax.org.

Job Location
Farmington, Connecticut, United States
Position Type
Full-Time/Regular
 

Read the full job description

Professor Mammalian Genetics

Date Posted:
5/16/2017

Jackson Labs

ME

Professor Positions - The Jackson Laboratory for Mammalian Genetics

Tracking Code
5803
Job Description

 

The Jackson Laboratory for Mammalian Genetics, in Bar Harbor, Maine, is inviting applications for Assistant, Associate and Full Professors. Faculty on the Bar Harbor campus use genetic and genomic approaches to conduct basic research on fundamental biological problems and mechanisms of disease with emphasis on the mouse as a model system. In 2017, primary areas of  faculty recruitment will include:

 

  • Cancer Biology and Cancer Genomics
  • Computational Biology and Bioinformatics
  • Immunology
  • Metabolic Disorders and Genetics of Aging
  • Statistical and Systems Genetics

 

The Jackson Laboratory offers a uniquely collaborative scientific research environment. Faculty are supported by outstanding scientific services, unparalleled mouse and genomic resources, postdoctoral and predoctoral training programs, and numerous courses and conferences centered on the mouse as a genetic model for human biology and disease.

 

Required Experience

Candidates must have a Ph.D., M.D. or D.V.M. degree, and 4-5 years of relevant postdoctoral training, with an exceptional record of research accomplishment, and the ability to develop a competitive, independently funded research program. Opportunities are available for shared mentorship of trainees, and integration with the three Jackson Laboratory campuses in Maine, Connecticut and California.

 

Applicants must apply online.  Please submit a curriculum vitae and a concise statement of research interests as one document, using the link below.  In addition, please have three letters of reference sent to:facultyjobs@jax.org.

Job Location
Bar Harbor, Maine, United States
Position Type
Full-Time/Regular
 

Read the full job description

Professor Bioinformatics and Computational Biology

Date Posted:
5/16/2017

Jackson Labs

ME

Professor Positions - Bioinformatics & Computational Biology

Tracking Code
5848
Job Description

 

The Jackson Laboratory is inviting applications for Assistant, Associate and Full Professors in Bioinformatics and Computational Biology Research at both The Jackson Laboratory for Mammalian Genetics campus in Bar Harbor, Maine, and The Jackson Laboratory for Genomic Medicine campus in Farmington, Connecticut.

 

The Jackson Laboratory (JAX) is an independent, nonprofit biomedical research institution and features a National Cancer Institute-designated Cancer Center. JAX is a highly collaborative environment that fosters multidisciplinary approaches to investigate complex biological questions. Our faculty use genetic and genomic approaches to conduct basic and translational research on fundamental biological processes in disease using mouse models and human studies. JAX is home to internationally recognized information resources including the Mouse Genome Informatics (MGI) database and the Gene Ontology and Human Phenotype Ontology projects. 

 

We are seeking faculty who are pursuing computational approaches in the following research areas:

 

 Systems genetics

 Current research at JAX includes systems approaches to complex trait analysis, including genetic analysis of transcript expression, histone modifications, and protein abundance.

 

Cancer Computational Biology

Current research focus areas include models of cancer biology, tumor evolution, tumor-immune systems interactions, and mechanisms of therapy response and resistance.

 

Cross-organism bioinformatics

Current research at JAX includes initiatives to create and align animal models of human disease with clinical genetics. This work includes algorithms to translate results for both the genome and phenome.

 

Required Experience

 

Successful candidates must hold a Ph.D. and/or M.D. degree; have two to five years of postdoctoral training; have a record of significant research accomplishments; and present long-term research goals consistent with establishing and/or maintaining a highly successful research program.

 

Applicants should submit a curriculum vitae and a concise statement of research interests and plans as one document. In addition, please arrange to have three letters of reference sent to: facultyjobs@jax.org.

 

Job Location
Bar Harbor, Maine, United States
Position Type
Full-Time/Regular
 

Read the full job description

Computational Scientist

Date Posted:
5/16/2017

Jackson Labs

CT

Computational Scientist

Tracking Code
5888
Job Description

Computational Scientist

 (Application/Assistant/Associate/Full)

 

 

About The Jackson Laboratory for Genomic Medicine: Comprising 183,000 square feet of highly advanced, state-of-the-art laboratories and supporting facilities, JAX-GM is conveniently located midway between NYC and Boston, in the heart of Connecticut. JAX-GM is part of an exciting, internationally-recognized research and educational institution with unparalleled genomic resources and research support services.

 

About the position: JAX-GM is seeking an exceptionally talented and highly motivated Computational Scientist to lead the research efforts central to the success of its computational sciences department.  The Computational Sciences department works collaboratively with faculty at The Jackson Laboratory to understand the biology of diseases like cancer, diabetes and Alzheimer’s.

 

The successful candidate will be responsible for leading a variety of computational research projects to understand the biology of diseases through large-scale genomic data integration and analysis, algorithm comparison and benchmarking, and machine learning.

 

The successful candidate will thrive in a proactive, can-do culture and enjoy working in a small, cross-disciplinary team as well as collaborating with other computational scientists and software developers at JAX.

 

 

KEY RESPONSIBILITIES

 

  • Lead efforts in the analysis of large public datasets and databases relevant to cancer genomics and immuno-oncology, such as TCGA, ICGC, ENCODE and GTEx.
  • Leverage internal and public cancer genomic and clinical data to support decisions on clinical indications and target populations.
  • Direct the development of new tools and algorithms for integrative analysis of DNA-seq, RNA-seq, and whole exome sequencing datasets for the development of biomarkers.

 

 

MINIMUM QUALIFICATIONS

 

  • PhD in Cancer Genomics, Computational Biology or Bioinformatics is preferred. PhD in other fields combined with postdoctoral or work experience in the field of computational biology will be considered.
  • Deep understanding of machine learning algorithms including deep learning methods.
  • Experience in image and video processing will be a plus.
  • Technical expertise in NGS data processing and analysis, including extensive hands-on experience with whole exome and RNA sequencing.
  • Advanced programming expertise in Python and R.
  • Experience with modern techniques in data science and machine learning, such as feature engineering, cross-validation, clustering and PCA, and supervised learning.
  • Experience contributing to scientific software development efforts to deliver pipelines, tools, and data analyses.
  • Experience working in a cloud computing environment, Docker, Luigi, pandas, and/or Spark will be a plus.
  • Experience in grant writing will be a plus.

 

 

MORE ABOUT JAX

 

JAX began in 1929 with a small group of scientists dedicated to the emerging field of genetics. We now have over 1,700 scientists, technicians, and support staff, including over 50 Principle Investigators in five primary disease areas: cancer, reproductive biology, immunology, metabolic processes and neuroscience. Our fundamental contributions to biomedical research include cancer genetics and establishing the mouse as the premier research animal model.

 

  • Uncover more of our historic milestones, including the 26 Nobel prizes associated with our research, resources, and education
  • Read our latest news & insights for a glimpse at how we’re impacting the future of biomedicine
  • Follow the progress we’re making on our quest to improve human health via our recent research highlights

 

 

EEO: All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.

 

Job Location
Farmington, Connecticut, United States
Position Type
Full-Time/Regular
 

Read the full job description

Associate Research Scientist

Date Posted:
5/16/2017

Jackson Labs

ME

Associate Research Scientist

Tracking Code
5925
Job Description

 

The Jackson Laboratory (http://www.jax.org) in Bar Harbor, Maine, USA, is recognized internationally for its excellence in research, unparalleled mouse resources, outstanding training environment characterized by scientific collaboration, and exceptional core services - all within a spectacular setting adjacent to Acadia National Park. The Jackson Laboratory was voted among the top 15 “Best Places to Work in Academia” in the United States in a poll conducted by The Scientist magazine.

 

 The Carter Lab at The Jackson Laboratory is seeking an Associate Research Scientist in the genetics of Alzheimer’s disease. Our group (www.jax.org/research-and-faculty/research-labs/the-carter-lab) is developing novel computational methods to derive biological models from large-scale genomic data. The strategies we pursue involve combining statistical genetics concepts such as epistasis and pleiotropy to understand how many genetic factors combine to control disease-related processes in neurodegeneration. We are therefore seeking an individual with expertise in epistasis analysis as it pertains to studies of Alzheimer’s genetics in humans.

 

 Broad skills in statistical genetics, the genetics of human disease, and Alzheimer’s etiology are required. Applicants must have a commitment to solving biological problems and communicating these solutions.

 

Required Skills

 

Applicants should have a PhD. in the computational sciences, and postdoctoral experience related to bioinformatics and computational biology, particularly as relates to Alzheimer's disease. Candidates should have a record of scientific achievements including journal publications and conference presentations.

 

Job Location
Bar Harbor, Maine, United States
Position Type
Full-Time/Regular

Read the full job description

Professor Genetics of Aging

Date Posted:
5/16/2017

Jackson Labs

ME

Professor Positions - Genetics of Aging

Tracking Code
5939
Job Description

The Jackson Laboratory is an independent, nonprofit, biomedical research institution with 3 campuses located in Bar Harbor, Maine, Farmington, Connecticut and Sacramento, California.  The Laboratory’s mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health. We are actively expanding our research program in the genetics of aging, and are recruiting faculty members with a research focus in this field, especially those centered on cellular mechanisms of aging.  Open positions are:

 

Assistant, Associate or Full Professor – Aging Genetics Faculty members will run independent labs for relevant biomedical research on the biology of aging and age-associated diseases, will participate in The Jackson Laboratory’s aging programs, and will mentor graduate students, postdoctoral associates and research staff, in a collaborative and supportive environment.

 

 

 

Required Skills

 

We seek scientists with Ph.D., and/or M.D. degrees, and 3 - 5 years of postdoctoral experience.

Required Experience

Applicants must have completed 3 - 5 years of postdoctoral training and have a record of research excellence. Candidates should have the ability to develop a competitive, independently funded research program that takes advantage of the mouse as a genetic model for understanding human biology, diseases of aging, and longevity.  

Job Location
Bar Harbor, Maine, United States
Position Type
Full-Time/Regular

Read the full job description

Senior Research Scientist

Date Posted:
5/16/2017

Jackson Labs

CT

Senior Research Scientist

Tracking Code
6180
Job Description

Senior Research Scientist

 

 

About JAX-GM: Comprising 183,000 square feet of highly advanced, state-of-the-art laboratories and supporting facilities, the brand new JAX-GM conveniently sits midway between NYC and Boston in the heart of Connecticut. JAX-GM is part of an exciting $1.1 billion venture between the state of Connecticut and The Jackson Laboratory, an internationally-recognized research and educational institution with outstanding genomic resources and research support services.

 

About the position: This position requires a scientist with expertise in genomics in general and epigenomics/chromatin biology in specific to support the JAX Center for 3D genome biology. This center is currently funded by two NIH center grants (4DN and ENCODE) and the Roux endowment, and its mission is to develop cutting-age technologies for comprehensive mapping of 3D genome organizations in human and mouse, and to uncover the topological mechanisms that control important genome functional modulation including gene transcription regulation. In this position within the JAX 3D genome center, the incumbent will provide scientific and programmatic leadership in the strategic discussion, technological development, experimental implementation, and data analysis/ interpretation, etc. The role will involve significant interaction and collaboration within the center, The Jackson Laboratory, and with external partners, particularly within the 4DN and ENCODE consortia.  This position offers great growth opportunity to contribute both in novel technology development and advanced genomic discoveries that have immediate relevance in genetics and clinical significance in an innovative and fast-paced team environment.

 

 

KEY RESPONSIBILITIES

 

  • Design and implement large NIH grants and act as co-PI and Program Director (20-30%)
  • Act as co-Investigator on collaborative research grants, internally and as sub-contract (40%)
  • Act as sub-contract PI to outside research grants (20%)
  • Participate in international forums designed to set standard operating procedures for genetic/genomic research (15-20%)

 

 

MINIMUM QUALIFICATIONS

 

  • PhD or equivalent in molecular biology, genomics, or related discipline with 5+ years of relevant experience in academic institutions or biotech/industry
  • Knowledge and experience in the preparation and execution of successful grant proposals to public or private funding institutions
  • Evidence of scientific productivity demonstrated by publications in high-quality peer-reviewed journals
  • Knowledge and experience in developing and managing successful large scale scientific programs, including management of subcontracts with external investigators, including building an effective and productive research team
  • Experience overseeing the development of relevant research projects by using new technologies, such as DNA sequencing and computational modeling
  • Demonstrated ability to work with people across departments and scientific fields, and to gain their cooperation and commitment to projects with demanding deadlines
  • Excellent written and oral communication skills
  • Excellent organizational skills to track multiple inputs, delegate tasks and track their progress
  • Demonstrated ability to maintain a budget for independent and large scale research awards

 

 

MORE ABOUT JAX

 

The Jackson Laboratory began in 1929 with a small group of scientists dedicated to the emerging field of genetics. We now have over 1,700 scientists, technicians, and support staff, including over 50 Principle Investigators in five primary disease areas: cancer, reproductive biology, immunology, metabolic processes and neuroscience. Our fundamental contributions to biomedical research include cancer genetics and establishing the mouse as the premier research animal model.

 

  • Uncover more of our historic milestones, including the 26 Nobel prizesassociated with our research, resources, and education
  • Read our latest news & insightsfor a glimpse at how we’re impacting the future of biomedicine
  • Follow the progress we’re making on our quest to improve human health via our recent research highlights

 

 

EEO: All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.

Job Location
Farmington, Connecticut, United States
Position Type
Full-Time/Regular

Read the full job description

Clinical Veterinarian

Date Posted:
5/16/2017

Jackson Labs

ME

Clinical Veterinarian

Tracking Code
6271
Job Description

The Clinical Veterinarian directs the clinical care of mice at The Jackson Laboratory in Bar Harbor, ME and assists other Comparative Medicine and Quality Veterinarians in ensuring the health and welfare of JAX mice, compliance with laws and regulations (consistent with OLAW Assurance) as well as continued AAALACi accreditation.  This individual participates in research projects and may present courses or research results at conferences.

 

Key responsibilities:

  • Provides guidance and support in regards to veterinary clinical medicine
  • Participates as a veterinary member of the Animal Care and Use Committee including protocol review and policy writing
  • In conjunction with the JAX Trainers, provides biomethods training to animal care associates and research personnel
  • Responds to questions and concerns raised by staff and internal and external customers related to the care, use, health, and welfare of mice. Assists in responding to animal care and welfare issues. Participates in research studies in collaboration with laboratory staff. Participates in writing research reports and may assist in applying for internal or external grant funding.
  • Supports investigation of clinical cases or cases involving known or suspected infectious agents.
  • Manages and negotiates health certificates.
  • On-call duty is required
Required Skills
  • DVM/VMD degree and a U.S. license to practice veterinary medicine; possesses qualifications needed to become licensed to practice veterinary medicine in Maine and to become certified by USDA in Maine.
  • At least 2 years’ experience working as a laboratory animal veterinarian; completion of a laboratory animal residency program a plus.
  • Board eligibility or certification in a relevant veterinary specialty, e.g., ACLAM
  • Skill in reading and comprehending technical specifications, laws, and codes as they relate to regulatory compliance.
  • Excellent initiative and organizational skills to prioritize complex tasks, projects, and workflow, and use independent judgment to make decisions regarding operations and deadlines.
  • Possess traits of good judgment, confidentiality, and discretion with colleagues and constituents.
  • Proven ability to analyze and synthesize information, and demonstrated resourcefulness in finding appropriate solutions to problems and initiative in presenting alternatives and implementing solutions to ensure effective change and/or eliminate or mitigate potential negative effects
  • Demonstrated positive attitude and professional manner in all interactions; demonstrated commitment to continuous learning and professional development
  • Ability to communicate effectively with others in person and in writing to clearly exchange information with people representing a wide diversity of disciplines and levels of sophistication
  • Ability to communicate effectively in writing and verbally to achieve exchange of information with people representing a wide diversity of disciplines and levels of sophistication.   

 

Please submit resume and cover letter as a single document to complete the application process.  The successful candidate for this position will be required to clear a Background Check prior to starting the position.

 

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.

 

Job Location
Bar Harbor, Maine, United States
Position Type
Full-Time/Regular

Read the full job description

Technical Information Scientist

Date Posted:
5/16/2017

Jackson Labs

ME

Technical Information Scientist

Tracking Code
6346
Job Description

Technical Information Scientist

 

 

The individual in this role may be located at The Jackson Laboratory’s Farmington, CT campus, Bar Harbor, ME campus, or Sacramento, CA campus.

 

About the position: The Jackson Laboratory has a full time opening for a Technical Information Scientist (TIS).  The successful candidate will be a highly-trained, self-motivated research scientist excited about science but looking for an alternative to a career writing grants and performing experimental bench work. The primary focus of this position is assisting investigators with their email and phone inquiries and helping them achieve their mouse-related research goals.

 

The TIS role also includes opportunities to:

 

  • Interface with researchers worldwide
  • Travel and deliver scientific presentations
  • Develop educational marketing literature
  • Build technical sales skills
  • Remain current in your field of interest (as it relates to mouse models of disease)
  • Participate in leadership opportunities
  • Continue to develop your scientific career as part of a diverse, dynamic team within a non-profit business setting

 

 

KEY RESPONSIBILITIES

 

  • Develop and deliver educational presentations, both off-site and via webinar
  • Serve as the principal internal scientific resource for JAX Mice and Services staff
  • Support the promotion and use of mouse models and related services 

 

 

MINIMUM QUALIFICATIONS

 

  • A PhD in the biological sciences is preferred, but a Master's degree with extensive research experience, including mouse genetics, will be considered 
  • Exceptional written and verbal communication skills
  • Strong problem solving skills
  • The ability to travel (10-25%) to deliver engaging presentations to large audiences
  • Research experience in cancer, immunology, autoimmunity/inflammation, neurobiology, or metabolic disease is an asset

 

 

MORE ABOUT JAX

 

JAX began in 1929 with a small group of scientists dedicated to the emerging field of genetics. We now have over 1,700 scientists, technicians, and support staff, including over 50 Principle Investigators in five primary disease areas: cancer, reproductive biology, immunology, metabolic processes and neuroscience. Our fundamental contributions to biomedical research include cancer genetics and establishing the mouse as the premier research animal model.

 

  • Uncover more of our historic milestones, including the 26 Nobel prizes associated with our research, resources, and education
  • Read our latest news & insights for a glimpse at how we’re impacting the future of biomedicine
  • Follow the progress we’re making on our quest to improve human health via our recent research highlights

 

 

EEO: All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.

Job Location
Bar Harbor, Maine, United States
Position Type
Full-Time/Regular

Read the full job description

Senior Computational Scientist

Date Posted:
5/16/2017

Jackson Labs

CT

Senior Computational Scientist

Tracking Code
6384
Job Description

Senior Computational Scientist

 

 

About JAX-GM: Comprising 183,000 square feet of highly advanced, state-of-the-art laboratories and supporting facilities, the brand new JAX-GM conveniently sits midway between NYC and Boston in the heart of Connecticut. JAX-GM is part of an exciting $1.1 billion venture between the state of Connecticut and The Jackson Laboratory, an internationally-recognized research and educational institution with unparalleled genomic resources and research support services.

 

About the position: A position is available immediately for a Senior Computational Scientist to join the lab of Dr. Charles Lee at the Jackson Laboratory for Genomic Medicine. The research focus of the lab is in the area of structural variation in the human genome and association with human phenotype and disease.  This position offers the opportunity to make leading contributions to cutting edge research in human genetics, disease biology, and translational research.

 

For more on Dr. Charles Lee and his lab's exciting research, visit the Lee Lab online.

 

 

KEY RESPONSIBILITIES

 

  • Develop new algorithms / pipelines for studying SVs in the human genome.
  • Data analysis through established algorithms / pipelines to study genome structural variation and its contribution to human disease and genome evolution.

 

 

REQUIRED SKILLS

 

  • Creativity and eagerness to learn new technologies and science
  • Enthusiasm for working in a dynamic, high-performance research team environment
  • Strong communication skills

 

 

MINIMUM QUALIFICATIONS

 

  • A Ph.D. in bioinformatics, computer science, biostatistics or any relevant field of study
  • Demonstrable aptitude and expertise in the niche areas of genome variation and/or cancer genomics
  • Solid publication track record
  • Proficiency in programming (Python, Java, C++) and statistical analysis (R, MATLAB)
  • Experience in UNIX-like operating systems and high-performance computing environments
  • Demonstrable leadership in previous research projects
  • Experience with applications for external research funding
  • Track record of developing algorithms and tools in the area of genome variation and/or cancer biology
  • Familiarity with large datasets from big consortium projects such as TCGA/ICGC/ENCODE and 1000 Genomes
  • Experience in High Throughput Sequence (HTS) data analysis, microarray data analysis, data integration or evaluation of new analytical tools and technology

 

 

MORE ABOUT JAX

 

JAX began in 1929 with a small group of scientists dedicated to the emerging field of genetics. We now have over 1700 scientists, technicians, and support staff, including over 50 Principle Investigators in five primary disease areas: cancer, reproductive biology, immunology, metabolic processes and neuroscience. Our fundamental contributions to biomedical research include cancer genetics and establishing the mouse as the premier research animal model.

 

  • Uncover more of our historic milestones, including the 26 Nobel prizes associated with our research, resources, and education
  • Read our latest news & insights for a glimpse at how we’re impacting the future of biomedicine
  • Follow the progress we’re making on our quest to improve human health via our recent research highlights

 

 

 

EEO: All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.

Job Location
Farmington, Connecticut, United States
Position Type
Full-Time/Regular
 

Read the full job description

Computational Scientist

Date Posted:
5/16/2017

Jackson Labs

CT

Computational Scientist

Tracking Code
6383
Job Description

Computational Scientist

(Associate/Full/Senior)

 

 

About JAX-GM: Comprising 183,000 square feet of highly advanced, state-of-the-art laboratories and supporting facilities, the brand new JAX-GM conveniently sits midway between NYC and Boston in the heart of Connecticut. JAX-GM is part of an exciting $1.1 billion venture between the state of Connecticut and The Jackson Laboratory, an internationally-recognized research and educational institution.

 

About the position: Computational Scientists participate in a collaborative bioinformatics program aligned with institutional strategy and direction, and make leading contributions to the cutting-edge projects at The Jackson Laboratory for Genomic Medicine.

 

 

KEY RESPONSIBILITIES

 

  • Collaborate with the research faculty & genetic resource scientists on projects of wide-ranging complexity across a diverse array of biomedical disciplines (such as cancer biology, ageing, immunology, infectious diseases, metabolomics, neural disorders, muscular disorders, stem cell and developmental biology, and statistical genetics & biostatistics)
  • Work with JAX Mice & Services staff to meet the analytical needs of clients and partners
  • Sustain collaborations with the research faculty and staff on both the Farmington, Connecticut and Bar Harbor, Maine campuses; and visit the Sacramento, California facility on a regular basis

 

 

REQUIRED SKILLS

 

  • Excellent written and verbal communication skills, including the ability to present results to the JAX community, conferences, and workshops
  • Must be continuous learners and proactive contributors
  • Must possess the desire to contribute to team projects on an ongoing basis

 

 

MINIMUM QUALIFICATIONS

 

  • An In-depth knowledge of, and prior experience with, High Throughput Sequence (HTS) data analysis (DNA Seq, mRNA Seq, ChIP Seq, micro RNA Seq etc), microarray data analysis, experimental design, data integration, algorithm development, development of sequence analysis tools (bioinformatics programming), evaluation of analytical tools and technology, and delivering training to the research community
  • Must have experience in Bioinformatics research
  • Demonstrated experience managing projects and collaborations is key
  • Prior successes in and desire to contribute to team projects on an ongoing basis is a must

 

 

DESIRED EXPERIENCE

 

  • PhD in Bioinformatics, Computer Science, Biostatistics or any relevant area is preferred
  • Candidates with a proven track record of “omics” data analysis, statistical genetics & biostatistics, independent collaborative work, and leading contributions to a biological discipline are preferred
  • Level of position will be determined by the incumbents’ years of Bioinformatics research experience, educational background and leadership experience.

 

 

MORE ABOUT JAX

 

JAX began in 1929 with a small group of scientists dedicated to the emerging field of genetics. We now have over 1,700 scientists, technicians, and support staff, including over 50 Principle Investigators in five primary disease areas: cancer, reproductive biology, immunology, metabolic processes and neuroscience. Our fundamental contributions to biomedical research include cancer genetics and establishing the mouse as the premier research animal model.

 

  • Uncover more of our historic milestones, including the 26 Nobel prizes associated with our research, resources, and education
  • Read our latest news & insights for a glimpse at how we’re impacting the future of biomedicine
  • Follow the progress we’re making on our quest to improve human health via our recent research highlights

 

 

 

EEO: All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.

 

Job Location
Farmington, Connecticut, United States
Position Type
Full-Time/Regular
 

Read the full job description

Bioinformatics Analyst

Date Posted:
5/16/2017

Jackson Labs

CT

Bioinformatics Analyst I/II/III

Tracking Code
6385
Job Description

Bioinformatics Analyst I, II, III

 

About JAX-GM: Comprising 183,000 square feet of highly advanced, state-of-the-art laboratories and supporting facilities, the brand new JAX-GM conveniently sits midway between NYC and Boston in the heart of Connecticut. JAX-GM is part of an exciting $1.1 billion venture between the state of Connecticut and The Jackson Laboratory, an internationally-recognized research and educational institution with unparalleled genomic resources and research support services.

 

 

About the position: Bioinformatics Analysts work under the supervision of the PI, research scientist, or department head, to analyze complex bioinformatics research. Typical projects include, but are not limited to, all classes of High Throughput Sequence (HTS) data analysis (DNA Seq, mRNA Seq, ChIP Seq, micro RNA Seq etc), experimental design consulting, data integration, algorithm development, development of sequence analysis tools (bioinformatics programming), evaluation of analytical tools and technology, and delivering training to the research community.

 

Characteristic distinctions from level I to level III include increased ability to work independently, increased breath of bioinformatics knowledge and tools, and increased understanding of the biological research domains. Level III analysts may pursue limited co-pi collaborations with research faculty.

 

 

KEY RESPONSIBILITIES

 

  • Level I Analyst duties include entry level statistical analysis, algorithm implementation, bioinformatics programming, running programs and packaging results for clients. Evaluating data for quality assurance, and mining bioinformatics databases as a service for clients. Tasks are complex, but the incumbent has support of immediate supervisor or mentor for directional support during execution of work.
  • Level II Analyst duties include basic statistical analysis, algorithm implementation, bioinformatics programming, running programs and packaging and interpreting results for clients. Conducting, analyzing, and interpreting quality assurance data. Mining bioinformatics databases and interpreting results. Often receives tasks from clients but requires attention from supervisor or mentor for additional directional support.
  • Level III Analyst work directly with clients, and receive work directly from clients. Includes all the responsibilities of Level II Analyst but works more independently and provides more in-depth interpretation of results. Level III Analyst act as mentors to junior level colleagues. Presents materials at seminars and assists in department level strategic planning.

 

 

MINIMUM QUALIFICATIONS

 

  • Level I requires BS or MS degree in Bioinformatics or relevant biological sciences degree. Incumbents who have not achieved Master's degree may compensate for lack of a degree with at least five years of professional bioinformatics work experience. Works under close supervision.
  • Level II requires MS or PhD degree in Bioinformatics or relevant biological sciences degree. Incumbents who have not achieved a Ph.D, may compensate with a Master's degree and at least five years of professional work experience in bioinformatics. Works with limited supervision for tasks performed.
  • Level III requires MS or PhD degree in Bioinformatics or relevant biological sciences degree. Incumbents who have not achieved the PhD level will have at least seven years profession work experience in the bioinformatics domain.   Incumbents with a PhD will have completed a bioinformatics postdoctoral fellowship and/or have a minimum of two years of professional work experience in the bioinformatics domain.
  • Bioinformatician will be expected to generate pipelines for the discovery and annotation of lncRNAs. They will also be expected to integrate diverse data sets including ATAC-Seq, ChIP-Seq and GWAS.

 

 

MORE ABOUT JAX

 

JAX began in 1929 with a small group of scientists dedicated to the emerging field of genetics. We now have over 1,700 scientists, technicians, and support staff, including over 50 Principle Investigators in five primary disease areas: cancer, reproductive biology, immunology, metabolic processes and neuroscience. Our fundamental contributions to biomedical research include cancer genetics and establishing the mouse as the premier research animal model.

 

  • Uncover more of our historic milestones, including the 26 Nobel prizes associated with our research, resources, and education
  • Read our latest news & insights for a glimpse at how we’re impacting the future of biomedicine
  • Follow the progress we’re making on our quest to improve human health via our recent research highlights

 

EEO: All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.

 

 

 

 

Job Location
Farmington, Connecticut, United States
Position Type
Full-Time/Regular

Read the full job description

Scientist Genome Editing

Date Posted:
5/16/2017

Jackson Labs

CT

Scientist, Genome Editing Service

Tracking Code
6396
Job Description

Scientist, Genome Editing Service

 

About The Jackson Laboratory for Genomic Medicine: Comprising 183,000 square feet of highly advanced, state-of-the-art laboratories and supporting facilities, JAX-GM is conveniently located midway between NYC and Boston, in the heart of Connecticut. JAX-GM is part of an exciting, internationally-recognized research and educational institution with unparalleled genomic resources and research support services.

 

About the position: Working under the general direction of the Director of Cellular Engineering, the incumbent scientist will manage the genome editing service, initially of human induced pluripotent stem cells.  The objective of this role is to improve the efficiency of editing methods and the range of alleles and cell lines offered by the service.

 

The candidate will manage the day-to-day operation of the gene editing service at JAX-GM.  Responsibilities will include helping researchers with the design of gene editing experiments, assessment of the feasibility of each project, execution of genome editing projects, and delivery of QC-validated cells to users in a reasonable time-frame.  Good communication with the Director of Cellular Engineering will be essential to manage users’ expectations, particularly in the event of unexpected/unavoidable technical difficulties.

 

 

KEY RESPONSIBILITIES

 

  • Project execution and troubleshooting: Responsible for the operational oversight, execution and troubleshooting of gene editing projects.  Discuss project design, go/no decision points, and progress with internal and external collaborators. Perform experiments and obtain data with minimal guidance, and guide junior staff to develop similar competencies.
  • Optimization and innovation: Stay current in cutting-edge approaches and support Research and Development efforts driven by cellular engineering service leadership. Proactively apply new and existing techniques and technologies to improve scientific value, quality and throughput.  Develop protocols.
  • High performance environment: Demonstrate and drive a positive, high performance environment with a culture of teamwork, continuous improvement and customer focus. Work collaboratively across teams to leverage expertise and resources across the organization to maximize success, resource use and positive impact.  Ensure a safe work environment is maintained at all times.
  • Progress reports and grant writing: Compile data and distribute progress reports on individual projects to all stakeholders.  Contribute to the preparation and submission of grant applications involving coordination of numerous functional areas and staff across the campus. 

 

 

MINIMUM QUALIFICATIONS

 

  • PhD in the cellular and/or developmental biology fields with 7+ years of practical experience in a research laboratory.
  • Excellent research project oversight skills, including adherence to procedures and best practices, plus detailed documentation and record-keeping skills.
  • Strong leadership skills, including a demonstrated ability to build key relationships and to influence and motivate others.
  • Demonstrated success in making important decisions, often under pressure and tight timeframes; demonstrated ability to meet deadlines.
  • Excellent oral and written communication skills.
  • Minimum of 3 years’ demonstrated ability to lead or mentor technical staff. Two years of direct management experience preferred.
  • Extensive knowledge of stem cell biology (mouse and/or human) and genome editing technologies with a proven track record of high impact publications in the field.
  • Technical expertise in CRISPR/Cas9-assisted genome editing of cells.
  • Knowledge of stem cell differentiation is desirable, but not essential.

 

 

MORE ABOUT JAX

 

JAX began in 1929 with a small group of scientists dedicated to the emerging field of genetics. We now have over 1,700 scientists, technicians, and support staff, including over 50 Principle Investigators in five primary disease areas: cancer, reproductive biology, immunology, metabolic processes and neuroscience. Our fundamental contributions to biomedical research include cancer genetics and establishing the mouse as the premier research animal model.

 

  • Uncover more of our historic milestones, including the 26 Nobel prizes associated with our research, resources, and education
  • Read our latest news & insights for a glimpse at how we’re impacting the future of biomedicine
  • Follow the progress we’re making on our quest to improve human health via our recent research highlights

 

 

EEO: All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.

 

 

Job Location
Farmington, Connecticut, United States
Position Type
Full-Time/Regular

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Genomics Scientist

Date Posted:
5/16/2017

Jackson Labs

ME

Genomics Scientist

Tracking Code
6401
Job Description

The Jackson Laboratory is seeking an enthusiastic, highly motivated individual with a strong background in molecular biology and genetics, and experience or a strong interest in next generation sequencing, to join our dynamic Next-Gen Sequencing team. Must be comfortable in a fast-paced, quickly changing environment and strive for the highest quality work.  The ideal candidate will provide process support to all aspects of the Next-Gen pipeline as well as manage new sequencing technologies from initiation to implementation. This includes development, testing, validation and implementation of new genomic technologies and protocols. Strong background and technical skills in molecular biology and sequencing technology improvement and optimization are required. Under very limited supervision, this person will be responsible for direct execution of experiments, assessment of QC for research/or service projects, and troubleshooting technical problems.  They ensure that sample preparation and sequencing production is maximized through new technology development, process optimization and pipeline and protocol development.  Independent decision making in regard to technical and project management issues is a critical necessity.

 

Key Responsibilities include:

 

  • Development, testing, validation and implementation of the new genomic technologies and methodologies, improvement and optimization of protocols including development and optimization of protocols for HTS library preparations
  • Engage in sample/sequencing QC analysis and provide solutions for protocol and data analysis improvements
  • Initiate scientific projects by applying new technologies and analysis capabilities
  • Publish in peer review journals, contribute to scientific research papers, grant applications and reports
Required Skills

 

  • Ph.D. in Genetics, Biochemistry, or Molecular Biology and extensive experience in different aspects of genomics, including an excellent understanding of sequence data and its applications
  • Demonstrated knowledge and experience in sequencing based molecular approaches and sequencing based interrogation.
  • Extensive experience in protocol development and optimization procedures.
  • Effective problem-solving and decision-making skills.
  • Strong analytical, organizational, and record-keeping skills.
  • Excellent verbal and written communication skills, including public-speaking and presentation skills.
  • Ability to work independently as well as part of a diverse team.
  • Experience in validation and documentation of new and complex molecular biology methods, and in HTS library preparation, operation and downstream data QC.
  • Strong publication record, and extensive experience in the preparation and handling of scientific manuscripts and reports
  • Prior LIMS (Laboratory Informatics Management System) experience is preferred.

 

Please include a cover letter and resume as one document. 

 

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.

 

Job Location
Bar Harbor, Maine, United States
Position Type
Full-Time/Regular

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Technology and Resource Development Scientist

Date Posted:
5/16/2017

Jackson Labs

ME

Technology & Resource Development Scientist

Tracking Code
6409
Job Description

The Jackson Laboratory is an independent, nonprofit biomedical research institution, dedicated to the discovery of the genetic basis for preventing, treating and curing human disease, and enabling research and education for the global biomedical community.

 

Genetic Resource Science (GRS) is seeking an enthusiastic, highly motivated individual with a strong background in molecular biology, genetics, and mouse physiology to join a growing team of scientists in the development of new and innovative resources! The incumbent will be responsible for identifying, initiating, and developing model resources and conducting research around new and existing mouse models across a number of therapeutic areas.   He/she will interact with the GRS leadership, GRS scientists, and research assistants/technicians to facilitate the development and/or implementation of innovative technologies, and to develop and establish genetic resource initiatives supporting the JAX mission. 

 

 

Key Responsibilities

 

  • Develop and characterize new mouse models and resources in key therapeutic areas of immunology, neurobiology and rare diseases.  
  • Identify collaborative opportunities for new resource development with both internal and external scientists and organizations.
  • Evaluate the potential of new projects and determine whether support for co-development should be sought through extramural funding.
  • Participate in the validation of existing and incoming Repository models to increase their utility to the research community.
  • Develop, write and serve as co-principal Investigator or principal investigator on NIH and private foundation grant proposals when required
  • Direct and manage a multi-project portfolio, publish key results, manage budgets and provide progress reports. Attend scientific meetings.
Required Skills
  • Ph.D. in Genetics, Biochemistry, or Molecular Biology and extensive experience in mouse physiology and working with mice, including an excellent understanding of transgenic and genome editing technologies
  • Knowledge of grant proposal preparation that would normally be acquired through 5 years of post-doctoral and/or independent grant-writing as a contributor or as PI.
  • Demonstrated ability to lead, direct, train and mentor teams
  • Positive attitude and professional manner in all interactions; demonstrated commitment to continuous learning and professional development
  • Demonstrated ability to support staff to thrive on change and keep pace with a fast paced, dynamic work environment which is externally focused
  • Evidence of strong scientific productivity that would be demonstrated by publication in high-quality peer-reviewed journals.
  • Ability to work with people across departments and gain their cooperation and commitment to projects with demanding deadlines
  • Excellent written and oral communication skills
  • Excellent organizational skills to track multiple inputs and maintain current drafts, arrange appropriate reviews, bring project to close in a timely manner to meet deadlines.

 

Please submit a CV and letter of interest as one document to complete application process. 

 

The Jackson Laboratory offers a dynamic and supportive work environment, competitive salaries and a generous benefits package including medical plan, retirement plan, paid vacation and an onsite fitness center.   

 

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.

 

Job Location
Bar Harbor, Maine, United States
Position Type
Full-Time/Regular
 

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Systems Analysts - Clinical Genomics

Date Posted:
5/16/2017

Jackson Labs

CT

Systems Analyst – Clinical Genomics

Tracking Code
6439
Job Description

Systems Analyst – Clinical Genomics

 

 

About The Jackson Laboratory for Genomic Medicine: Comprising 183,000 square feet of highly advanced, state-of-the-art laboratories and supporting facilities, JAX-GM is conveniently located midway between NYC and Boston, in the heart of Connecticut. JAX-GM is part of an exciting, internationally-recognized research and educational institution with unparalleled genomic resources and research support services.

 

About the position: Are you a motivated Systems Analyst who craves the excitement of a start-up company, coupled with the resources and support of an established and well-respected organization? At JAX-GM, our information technology is as exciting and progressive as our cutting-edge science; join our team to help plan, design, and launch efficient systems in support of scientific research functions and processes in the area of Clinical Genomics.

 

 

KEY RESPONSIBILITIES

 

The Systems Analyst will work with our computational scientists, system administrators, and other Research IT staff to create effective systems supporting scientific research in Clinical Genomics. This includes gathering and analyzing data and documenting business processes and requirements, and applying proven communication, analytical, and problem-solving skills to help maximize the benefit of Research IT system investments.

 

Working with Researchers:

  • Provide guidance, support, training and advice in Research IT systems to JAX scientists.
  • Investigate application issues, document findings: communicate with scientists to answer questions, troubleshoot problems and develop appropriate computational strategies to process and analyze their data.
  • Work closely with scientists to ensure that applications and Research IT services are current, appropriate and sufficient to serve their needs.
  • Install and update scientific applications in the Research IT environment, document system changes, write and maintain documentation for end users.
  • Develop and deliver training programs, tutorials and workshops for scientists on the optimal use of IT resources in their research projects.
  • Research and evaluate new products and services for applicability to in-house needs. Stay current with new trends and emerging information technologies and informatics tools, advocate for and lead the adoption of these technologies at JAX.
  • Assist in preparation for submitting grant proposals.

 

Working with IT:

  • Consult and collaborate with IT coworkers to determine best system configurations for applications.
  • Based on the scientific needs of the community, identify and recommend innovative solutions, and integrated proposals for server, storage, and network systems, including hardware and software acquisition, installation and administration.
  • Provide technical support internally and to external vendors including problem resolution for complex systems and storage solutions.
  • Help integrate IT resources with laboratory equipment, such as DNA sequencers and microscopes.
  • Set up and maintain scientific computing clusters and their associated batch scheduling systems, such as SGE or PBS.
  • Benchmark application and workflow performance and determine areas for improved efficiencies.

 

 

REQUIRED SKILLS

 

  • Able to work both independently and as part of a team
  • Strong analytical and problem-solving skills
  • Sense of urgency and ability to solve problems in a timely manner
  • Technical authority in area of specialty on assigned projects
  • Develop and maintain effective working relationships with scientists at all levels
  • Excellent communication (verbal/written) and presentation skills

 

 

MINIMUM QUALIFICATIONS

 

  • PhD in life/natural sciences with 3 years’ experience in clinical genomic data processing and analysis; OR an equivalent combination of proven education/training/knowledge/experience at a research-focused organization
  • Clinical Genomics background; hands-on experience with a broad spectrum of genomics and bioinformatics applications and next-generation sequence data collection, processing, and analysis, as applied in a clinical setup cognizant of PHI/PII data
  • Proficient in large dataset analysis in a related scientific discipline such as biology, biomedical informatics, Pharma, or clinical research
  • Knowledge of and experience with regulations pertinent to a clinical compliance such as HIPAA, HITECH, and CLIA
  • Strong technical knowledge of research computing system architecture, hardware components and software stack
  • Expertise with Unix/Linux systems, shell scripting, C/C++ programming, Python/Perl and other relevant tools
  • Experience with building, installing, configuring and supporting a wide range of commercial, open-source, and in-house developed scientific applications such as: Matlab, R, SAS, STATA, MySQL
  • Familiar with Cloud computing and storage infrastructure (e.g. AWS, EC2, Google, Azure)

 

 

MORE ABOUT JAX

 

JAX began in 1929 with a small group of scientists dedicated to the emerging field of genetics. We now have over 1700 scientists, technicians, and support staff, including over 50 Principle Investigators in five primary disease areas: cancer, reproductive biology, immunology, metabolic processes and neuroscience. Our fundamental contributions to biomedical research include cancer genetics and establishing the mouse as the premier research animal model.

 

  • Uncover more of our historic milestones, including the 26 Nobel prizes associated with our research, resources, and education
  • Read our latest news & insights for a glimpse at how we’re impacting the future of biomedicine
  • Follow the progress we’re making on our quest to improve human health via our recent research highlights

 

 

 

EEOAll qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.

 

Job Location
Farmington, Connecticut, United States
Position Type
Full-Time/Regular

Read the full job description

In Vivo Scientist

Date Posted:
5/16/2017

Jackson Labs

CA

Associate In Vivo Scientist/In Vivo Scientist

Tracking Code
6444
Job Description

There is a regular, full-time In Vivo Scientist position available at The Jackson Laboratory, Sacramento Facility. This is a Ph.D level position requiring experience and expertise in Patient Derived Xenografts (PDX), oncology and/or immuno-oncology research.  Additional experience in in vivo pharmacology, flow cytometry and FACS experience is also highly desired.   Ideal candidate has proven track record of publications I these fields of expertise. It is desirable but not required that candidate have 1-5 years of experience in a contract research organization, biotechnology or pharmaceutical company.  The individual will work hands on at the research bench with murine PDX models for oncology and/or immuno-oncology.  Managerial and project management experience is required. M.D. and M.S. candidates with equivalent experience will be considered.

Required Skills

Works at the research bench on multiple PDX studies simultaneously. Provides with regular updates regarding status of studies.

Leads a team of research technicians in supporting the department’s product lines.

Follows and supports all institutional policies, procedures and practices and ensure that staff is compliant.

Oversees technologist staff working on study and provides scientific and technical support as needed.

Supports and implements the development of new models for drug discovery in the areas of oncology and/or immunology.

Required Experience

Individuals with a Ph.D. (and/or M.D.) in oncology and/or immunology and a minimum of two (2) years of experience as a postdoctoral fellow or in a contract research laboratory, pharmaceutical industry, or equivalent experience will be considered for the Scientist level. Applicants with less experience may be considered for an In Vivo Associate Scientist position.  In Vivo Senior Scientists must have at least two (2) years of experience at the In Vivo Scientist level.

Individuals with a M.S. and a minimum of eight (8) years of basic research experience in oncology, immunology or pharmacology in a contract research laboratory, pharmaceutical industry, or equivalent experience will be considered.  

Experience with in vivo PDX study design and animal research (preferably rodents) and animal welfare and regulatory guidelines.

Documented ability to develop and lead technical teams.

Strong leadership skills including a demonstrated ability to build key relationships, influence and motivate others.

Demonstrated success in making important decisions, often under some pressure and tight time deadlines, which carry large financial consequences

 

 

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.

 

 

 

Job Location
Sacramento, California, United States

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Postdoctoral Fellow - Agent Based Modeling

Date Posted:
5/16/2017

Jackson Labs

CT

Postdoctoral Associate - Laubenbacher Lab

Tracking Code
6267
Job Description

Postdoctoral Associate

Dr. Reinhard Laubenbacher, Principal Investigator

 

About JAX-GM: Comprising 183,000 square feet of highly advanced, state-of-the-art laboratories and supporting facilities, the brand new JAX-GM conveniently sits midway between NYC and Boston in the heart of Connecticut. JAX-GM is part of an exciting $1.1 billion venture between the state of Connecticut and The Jackson Laboratory, an internationally-recognized research and educational institution with unparalleled genomic resources and research support services.

 

About the position: The Postdoctoral Associate will join the Laubenbacher Lab at JAX-GM and will play a key role in a project to build mathematical models of tumor evolution and tumor heterogeneity, using single cell genomics, transcriptomics, and tumor microenvironment data. Of particular interest is the relationship between tumor heterogeneity and resistance to therapies.

 

Find out about the distinct advantages enjoyed by our Postdoctoral Associates here.

 

 

KEY RESPONSIBILITIES

 

Responsibilities will include model development and coding, some data analysis, design and interpretation of model validation results, in collaboration with other research groups.

 

 

MINIMUM REQUIREMENTS

 

  • PhD in related field
  • Experience with agent-based modeling
  • C++ code development experience
  • Some experience with cancer genomics

 

 

In addition, JAX Postdoctoral Associates benefit from:

 

  • Research training and mentorship from award-winning faculty
  • Individualized career advising and a dedicated Postdoc Program Office
  • Superior scientific services and unparalleled mouse resources
  • A uniquely collaborative academic research environment
  • Guidance from JAX's Postdoctoral Training Committee to help you succeed
  • Professional skills workshops including JAX's holistic The Whole Scientist course
  • Free access to JAX’s world-renowned Courses & Conferences programs
  • Outstanding benefits and salary compensation above the NIH scale
  • Generous relocation assistance and free on-campus parking

 

 

MORE ABOUT JAX

 

JAX began in 1929 with a small group of scientists dedicated to the emerging field of genetics. We now have over 1,700 scientists, technicians, and support staff, including over 50 Principle Investigators in five primary disease areas: cancer, reproductive biology, immunology, metabolic processes and neuroscience. Our fundamental contributions to biomedical research include cancer genetics and establishing the mouse as the premier research animal model.

 

  • Uncover more of our historic milestones, including the 26 Nobel prizes associated with our research, resources, and education
  • Read our latest news & insights for a glimpse at how we’re impacting the future of biomedicine
  • Follow the progress we’re making on our quest to improve human health via our recent research highlights

 

 

EEO: All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.

Job Location
Farmington, Connecticut, United States
Position Type
Full-Time/Regular
 

Read the full job description

Postdoctoral Fellow Genomics

Date Posted:
5/16/2017

Jackson Labs

CT

Postdoctoral Associate - Ruan Lab

Tracking Code
6330
Job Description

Postdoctoral Associate

Dr. Yijun Ruan, Principal Investigator

 

About The Jackson Laboratory for Genomic Medicine: Comprising 183,000 square feet of highly advanced, state-of-the-art laboratories and supporting facilities, JAX-GM is conveniently located midway between NYC and Boston, in the heart of Connecticut. JAX-GM is part of an exciting, internationally-recognized research and educational institution with unparalleled genomic resources and research support services.

 

About the position: The Ruan Lab at JAX-GM is seeking to appoint a postdoctoral associate to participate in research directed toward elucidating the structures and dynamics of complex genomes. For more on the Ruan Lab’s research and goals, visit: https://www.jax.org/research-and-faculty/research-labs/the-ruan-lab

 

Our Postdoctoral Associates enjoy distinct advantages, including:

 

  • A uniquely collaborative environment that fosters interdisciplinary “team science” without departmental barriers
  • Unparalleled genomic resources and superior research support services
  • Close interaction with our award-winning faculty members
  • Partnerships with leading universities and medical centers
  • Numerous courses and conferences focused on genetics, genomics and biomedicine
  • Exceptional benefits, ample time off and other valuable programs
  • Working for an institution that has repeatedly been voted among the top 15 “Best Places to work in Academia” in the world by readers of The Scientist

 

 

MINIMUM QUALIFICATIONS

 

  • PhD (or nearing completion of PhD degree)
  • Background in human genetics or genomics and disease research
  • Publications (1st author highly advantageous)

 

 

MORE ABOUT JAX

 

The Jackson Laboratory began in 1929 with a small group of scientists dedicated to the emerging field of genetics. We now have over 1,700 scientists, technicians, and support staff, including over 50 Principle Investigators in five primary disease areas: cancer, reproductive biology, immunology, metabolic processes and neuroscience. Our fundamental contributions to biomedical research include cancer genetics and establishing the mouse as the premier research animal model.

 

  • Uncover more of our historic milestones, including the 26 Nobel prizes associated with our research, resources, and education
  • Read our latest news & insights for a glimpse at how we’re impacting the future of biomedicine
  • Follow the progress we’re making on our quest to improve human health via our recent research highlights

 

 

EEO: All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.

Job Location
Farmington, Connecticut, United States
Position Type
Full-Time/Regular
 

Read the full job description

Postdoctoral Fellow Bioinformatics

Date Posted:
5/16/2017

Jackson Labs

CT

Postdoctoral Associate - Palucka Lab

Tracking Code
6147
Job Description

Postdoctoral Associate

Dr. Karolina Palucka, Principal Investigator

?

 

About JAX-GM: Comprising 183,000 square feet of highly advanced, state-of-the-art laboratories and supporting facilities, the brand new JAX-GM conveniently sits midway between NYC and Boston in the heart of Connecticut. JAX-GM is part of an exciting $1.1 billion venture between the state of Connecticut and The Jackson Laboratory, an internationally-recognized research and educational institution with unparalleled genomic resources and research support services.

 

About the position: The Palucka Lab at JAX-GM is currently seeking motivated scientists interested in leveraging modern genomic advancements to study anti-tumor immune responses, and reprogramming the tumor microenvironment in human cancers in vitro and in vivo in humanized mice models. The overarching theme of the Palucka lab is to investigate the mechanisms of human immunity and to identify strategies for harnessing the power of the immune system to prevent and treat cancer. For more, visit the Palucka Lab online.

 

Find out about the distinct advantages enjoyed by our Postdoctoral Associates here.

 

 

MINIMUM QUALIFICATIONS

 

  • PhD and/or MD
  • Computational/bioinformatics experience, preferably in immunology
  • A track record of research publications
  • Substantial research experience with mice is desirable, but not required
  • The ambition to thrive within a highly collaborative, interdisciplinary research environment

 

 

In addition, JAX Postdoctoral Associates benefit from:

 

  • Research training and mentorship from award-winning faculty
  • Individualized career advising and a dedicated Postdoc Program Office
  • Superior scientific services and unparalleled mouse resources
  • A uniquely collaborative academic research environment
  • Guidance from JAX's Postdoctoral Training Committee to help you succeed
  • Professional skills workshops including JAX's holistic The Whole Scientist course
  • Free access to JAX’s world-renowned Courses & Conferences programs
  • Outstanding benefits and salary compensation above the NIH scale
  • Generous relocation assistance and free on-campus parking

 

 

MORE ABOUT JAX

 

JAX began in 1929 with a small group of scientists dedicated to the emerging field of genetics. We now have over 1,700 scientists, technicians, and support staff, including over 50 Principle Investigators in five primary disease areas: cancer, reproductive biology, immunology, metabolic processes and neuroscience. Our fundamental contributions to biomedical research include cancer genetics and establishing the mouse as the premier research animal model.

 

  • Uncover more of our historic milestones, including the 26 Nobel prizes associated with our research, resources, and education
  • Read our latest news & insights for a glimpse at how we’re impacting the future of biomedicine
  • Follow the progress we’re making on our quest to improve human health via our recent research highlights

 

 

EEO: All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.

Job Location
Farmington, Connecticut, United States
Position Type
Full-Time/Regular
 

Read the full job description

Postdoctoral Fellow Computational Biology

Date Posted:
5/16/2017

Jackson Labs

CT

Postdoctoral Associate - Ouyang Lab

Tracking Code
6148
Job Description

Postdoctoral Associate – Computational Biology

Dr. Zhengqing Ouyang, Principal Investigator

 

 

About JAX-GM: Comprising 183,000 square feet of highly advanced, state-of-the-art laboratories and supporting facilities, the brand new JAX-GM conveniently sits midway between NYC and Boston in the heart of Connecticut. JAX-GM is part of an exciting $1.1 billion venture between the state of Connecticut and The Jackson Laboratory, an internationally-recognized research and educational institution with unparalleled genomic resources and research support services.

 

About the position: A computational postdoctoral research position is available in the Ouyang Lab at The Jackson Laboratory for Genomic Medicine. The Ouyang Lab develops statistical and computational methodologies for analyzing high-throughput omics data. Areas of interest include but are not limited to 3D genomics and transcriptomics, single-cell omics, and regulome dynamics in development and diseases. For more, visit the Ouyang Lab online.

 

Exceptional candidates will have the opportunity to apply for prestigious postdoctoral awards in The Jackson Laboratory for Genomic Medicine. Fellows will be joining The Jackson Laboratory for Genomic Medicine in Farmington, Connecticut.

 

Find out about the distinct advantages enjoyed by our Postdoctoral Associates here.

 

 

MINIMUM QUALIFICATIONS

 

  • PhD training in computational biology, bioinformatics, statistics, computer science, applied mathematics, physics, engineering or a related quantitative area
  • Proven research experience and publication records in computational biology
  • Mastery of a statistical language (such as R) as well as a script language (such as Python)
  • Familiarity with Unix and computing in high-performance computer clusters
  • Strong communication skills and the ability to work in a team 

 

 

In addition, JAX Postdoctoral Associates benefit from:

 

  • Research training and mentorship from award-winning faculty
  • Individualized career advising and a dedicated Postdoc Program Office
  • Superior scientific services and unparalleled mouse resources
  • A uniquely collaborative academic research environment
  • Guidance from JAX's Postdoctoral Training Committee to help you succeed
  • Professional skills workshops including JAX's holistic The Whole Scientist course
  • Free access to JAX’s world-renowned Courses & Conferences programs
  • Outstanding benefits and salary compensation above the NIH scale
  • Generous relocation assistance and free on-campus parking

 

 

MORE ABOUT JAX

 

JAX began in 1929 with a small group of scientists dedicated to the emerging field of genetics. We now have over 1700 scientists, technicians, and support staff, including over 50 Principle Investigators in five primary disease areas: cancer, reproductive biology, immunology, metabolic processes, and neuroscience. Our fundamental contributions to biomedical research include cancer genetics and establishing the mouse as the premier research animal model.

 

  • Uncover more of our historic milestones, including the 26 Nobel prizes associated with our research, resources, & education
  • Read our latest news & insights for a glimpse at how we’re impacting the future of biomedicine
  • Follow the progress we’re making on our quest to improve human health via our recent research highlights

 

 

EEO: All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.

 

Job Location
Farmington, Connecticut, United States
Position Type
Full-Time/Regular

Read the full job description

Postdoc Computational genetics and systems biology

Date Posted:
5/16/2017

Jackson Labs

ME

Job Description

 

The Carter Lab (http://research.jax.org/faculty/greg_carter.html) at The Jackson Laboratory is seeking a Postdoctoral Fellow in computational genetics and systems biology. Our group is developing novel computational methods to derive biological models from large-scale genomic data. The strategies we pursue involve combining statistical genetics concepts such as epistasis and pleiotropy to understand how many genetic and environmental factors combine to control disease-related processes in animal models and human studies. We are especially interested in dissecting the genetic complexity of autoimmune disease, neurodegeneration, and cancer.

 

 

 

The Jackson Laboratory (http://www.jax.org) in Bar Harbor, Maine, USA, is recognized internationally for its excellence in research, unparalleled mouse resources, outstanding training environment characterized by scientific collaboration and exceptional core services - all within a spectacular setting adjacent to Acadia National Park. The Jackson Laboratory was voted among the top 15 “Best Places to Work in Academia” in the United States in a poll conducted by The Scientist magazine.

 

Exceptional postdoctoral candidates will have the opportunity to apply to become a JAX Postdoctoral Scholar, a selective award addressing the national need for research scientists who are accomplished in the broadly defined fields of genetics and genomics. The award includes an independent research budget, travel funds, and a salary above standard postdoctoral scale.

 

Required Skills

Applicants for both positions must have a PhD (or equivalent degree) in quantitative biology or another quantitative discipline such as computer science, physics, or applied mathematics.

Required Experience

Experience in statistical genetics and gene expression analysis is strongly recommended, and applicants must have a commitment to solving biological problems and good communication skills. Expertise in scientific programming languages including R, C/C++, Ruby, Perl, or Java is recommended. Expertise in cancer genetics, immunology, or neurological disease is desired but not required.

Job LocationBar Harbor, Maine, United StatesPosition TypeFull-Time/RegularSalary50,000.00 - 70,000.00 USD

 


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Postdoctoral Fellow Systems genetics

Date Posted:
5/16/2017

Jackson Labs

ME

Job Description

A postdoctoral associate position is available in the laboratory of Dr. Elissa Chesler at The Jackson Laboratory in Bar Harbor, Maine to utilize systems genetics approaches to identify heritable effectors of behavior. The Chesler lab uses quantitative genetics, bioinformatics and behavioral science to understand and identify the biological basis for the relationships among behavioral traits with an emphasis on alcohol and substance use related traits. We develop and apply cross-species genomic data integration, advanced computing methods, and novel high-precision, high-diversity mouse populations to find genes associated with a constellation of behavioral disorders and other complex traits. In addition, Dr. Chesler leads the recently formed NIDA Research Center of Excellence P50 to bring together behavioral genetics experts from around the country to form the Center for Systems Neurogenetics of Addiction. Overall, the tools, techniques, and collaborations enable us to relate mouse behavior to specific aspects of human disorders, to test the validity of behavioral classification schemes, and to find genes and genetic variants that influence behavior. 

 

The Jackson Laboratory (JAX) offers a unique research and training environment characterized by multidisciplinary scientific collaboration, unparalleled mouse resources, outstanding core services, and is located adjacent to Acadia National Park in coastal Bar Harbor, Maine. Translational research collaborations in genomics-based, personalized medicine are fostered through our new JAX Genomic Medicine campus in Farmington, CT. In addition to lab-based training, JAX has developed a unique program for trainees to expand their professional skills in science communication, entrepreneurship, teaching, mentoring and laboratory management to best prepare postdocs for future career opportunities.

Required Skills

 

Associate must be able to plan, execute and analyze an independent research project, as well as exceptional verbal and written communication skills. Preference will be given to self-motivated and career oriented individuals.

 

 

 

Required Experience

A Ph.D. in biological, behavioral, computational, or related sciences is required, and a strong training background in quantitative analysis, genomics, and genetics is preferred.

Job LocationBar Harbor, Maine, United StatesPosition TypeFull-Time/RegularSalary40,000.00 - 60,000.00 USD

 


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Postdoc Computational genetics and systems biology

Date Posted:
5/16/2017

Jackson Labs

ME

Posdoctoral Assoc. in Computational Genetics and Systems Biology

Tracking Code
6441
Job Description

The Churchill Lab (http://churchill-lab.jax.org) at The Jackson Laboratory is seeking a Postdoctoral Fellow in computational genetics and systems biology. Our group is developing novel computational methods for large-scale genomic data. Our approaches combine experimental design, and statistical modeling to establish causal relationships of genetic factors, RNA, and proteins on physiological traits in animal models. We are especially interested in metabolic diseases and aging.

 

 

 

The Jackson Laboratory (http://www.jax.org) in Bar Harbor, Maine, USA, is recognized internationally for its excellence in research, unparalleled mouse resources, outstanding training environment characterized by scientific collaboration and exceptional core services - all within a spectacular setting adjacent to Acadia National Park. The Jackson Laboratory was voted among the top 15 “Best Places to Work in Academia” in the United States in a poll conducted by The Scientist magazine.

 

Required Skills

Applicants must have a PhD in quantitative biology or another quantitative discipline such as computer science, physics, or applied mathematics. Experience in statistical genetics and gene expression analysis is strongly recommended. Applicants must have a commitment to solving biological problems and good communication skills. Expertise in scientific programming languages such as R or Python is recommended. 

Job Location
Bar Harbor, Maine, United States
Position Type
Full-Time/Regular
Salary
50,000.00 - 70,000.00 USD

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Postdoctoral Fellow Systems Genetics of Gene Regulation

Date Posted:
5/16/2017

Jackson Labs

ME

Postdoctoral Associate - Systems Genetics of Gene Regulation

Tracking Code
6199
Job Description

 The Munger Lab at The Jackson Laboratory is seeking a Postdoctoral Associateto apply systems genetics and experimental approaches to dissect gene regulatory networks and elucidate their downstream effects on cell function, physiology, and disease (http://mungerlab.com). Projects in the lab exploit the abundant natural genetic variation in advanced mapping populations, along with the genome-wide resolution of next generation genomics technologies, to predict new models of gene regulation, discover novel genetic interactions, and identify causal drivers of disease phenotypes. Most projects in the lab involve computational analysis and prediction as well as experimental validation components.

 

The Jackson Laboratory (JAX) offers a unique research and training environment characterized by multidisciplinary scientific collaboration, unparalleled mouse resources, outstanding core services, and is located adjacent to Acadia National Park in coastal Maine. Translational research collaborations in genomics-based, personalized medicine are fostered through our new JAX Genomic Medicine campus in Farmington, CT. In addition to lab-based training, JAX has developed a unique program for trainees to expand their professional skills in science communication, entrepreneurship, teaching, mentoring and laboratory management to best prepare postdocs for future career opportunities.

 

Exceptional candidates will have the opportunity to apply to become a JAX Postdoctoral Scholar, a selective award addressing the national need for research scientists who are accomplished in the broadly defined fields of genetics and genomics. The award includes an independent research budget, travel funds, and a salary above standard postdoctoral scale.

 

Required Skills

Ability to plan, execute and analyze an independent research project as well as exceptional verbal and written communication skills. Preference given to self-motivated and career oriented individuals.

Required Experience

A Ph.D. in biological or related sciences is required, and a strong training background in genetics, molecular biology, and/or cell biology is preferred. Training in bioinformatics and experience working with large-scale genomic datasets is desired but not required. Talented candidates will be provided opportunities for training in bioinformatics and statistics.

Job Location
Bar Harbor, Maine, United States
Position Type
Full-Time/Regular
Salary
50,000.00 - 70,000.00 USD

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Post Doctoral Fellow Systems Neuroscience of obesity and energy balance

Date Posted:
5/16/2017

Jackson Labs

ME

Postdoctoral Associate – Systems Neuroscience of Energy Balance and Obesity

Tracking Code
6194
Job Description

 

The O’Connell Lab at The Jackson Laboratory is seeking a Postdoctoral Associate in systems neuroscience of obesity and energy balance. Projects exploit genetically diverse mouse populations and environmental manipulations to investigate the impact of diet and body weight on the neural circuits that regulate appetite and energy expenditure. We use slice electrophysiology, in vivo Ca2+ imaging, and “-omics” approaches to identify factors that are involved in the CNS response to obesogenic environment at the molecular, cellular, and systems levels.

 

The Jackson Laboratory (http://www.jax.org) in Bar Harbor, Maine, USA, is recognized internationally for its excellence in research (e.g. The Nathan Shock Aging Center and Center for Novel Alzheimer’s Disease Models), unparalleled mouse resources, outstanding training environment characterized by scientific collaboration, and exceptional core services - all within a spectacular setting adjacent to Acadia National Park. Translational research collaborations in genomics-based, personalized medicine are fostered through our JAX Genomic Medicine campus in Farmington, CT. In addition to lab-based training, JAX has developed a unique program for trainees to expand their professional skills in science communication, entrepreneurship, teaching, mentoring and laboratory management to best prepare postdocs for future career opportunities.

 

Required Skills

Ability to plan, execute and analyze an independent research project as well as exceptional verbal and written communication skills. Preference given to self-motivated and career oriented individuals.

Required Experience

Required qualifications include a PhD or MD in Neuroscience or a related field and a commitment to solving biological problems. Expertise in scientific programming languages including R, C/C++, Ruby, Perl, or Java is recommended. Expertise in neurological disease is desired but not required.

 

Job Location
Bar Harbor, Maine, United States
Position Type
Full-Time/Regular
Salary
50,000.00 - 70,000.00 USD
 

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Postdoctoral Fellow Epigenetics Cancer and Regenerative medicine

Date Posted:
5/16/2017

Jackson Labs

CT

Postdoctoral Associate - Cheng Lab

Tracking Code
6280
Job Description

Postdoctoral Associate

Dr. Albert Cheng, Principal Investigator

??

About JAX-GM: Comprising 183,000 square feet of highly advanced, state-of-the-art laboratories and supporting facilities, the brand new JAX-GM conveniently sits midway between NYC and Boston in the heart of Connecticut. JAX-GM is part of an exciting $1.1 billion venture between the state of Connecticut and The Jackson Laboratory, an internationally-recognized research and educational institution with unparalleled genomic resources and research support services.

 

About the Cheng Lab: Dr. Albert Cheng’s lab (http://cheng.bio/) develops and applies technologies based on artificial DNA and RNA binding proteins to sense or induce sequence or epigenetic changes at target genomic loci or target RNA transcripts. Areas of focus include:

 

  • Improving precise genome editing
  • Developing novel approaches for epigenetic and transcript editing
  • Developing sensors for DNA and RNA
  • Developing imaging techniques for 3D structure of the genome
  • Developing experimental and computational toolkits for engineering artificial DNA and RNA binding proteins
  • Applying the above technologies to study the biology of cancer metastasis and cell differentiation, and exploring therapeutic applications of these technologies

 

One recent technology we developed is called “Casilio” (http://casil.io/) – a modular platform for artificial DNA binding enzymes for epigenome editing and chromatin imaging.

 

About the position: The Cheng Lab is seeking a Postdoctoral Associate to contribute to the development of genome and epigenome editing technologies, and their applications in cancer biology and regenerative medicine. The successful candidate will be innovative, self-motivated and a strong team player with great experimental and communication skills.

 

 

KEY RESPONSIBILITIES

 

  • Technology development for genome and epigenome editing and their applications in cancer biology and regenerative medicine
  • Lead projects and conduct experiments
  • May contribute to training of graduate students
  • Collaboration with other labs
  • Present works at conferences
  • Write manuscripts and contribute to grant writing

 

 

MINIMUM QUALIFICATIONS

 

Required:

  • PhD degree
  • First-authored publications in peer reviewed journals with impact factor > 5
  • 4+ years of wet lab experience
  • Tissue culture
  • Familiarity with next-generation sequencing
  • Molecular cloning

 

Preferred:

  • hiPSC/hESC/mESC culture experience
  • Cancer cell lines experience
  • ChIP-seq
  • Western blot
  • Confocal microscopy, live cell microscopy, FISH/immunocytochemistry
  • CRISPR/Cas
  • Dry lab experience

 

 

In addition, JAX Postdoctoral Associates benefit from:

 

  • Research training and mentorship from award-winning faculty
  • Individualized career advising and a dedicated Postdoc Program Office
  • Superior scientific services and unparalleled mouse resources
  • A uniquely collaborative academic research environment
  • Guidance from JAX's Postdoctoral Training Committee to help you succeed
  • Professional skills workshops including JAX's holistic The Whole Scientist course
  • Free access to JAX’s world-renowned Courses & Conferences programs
  • Outstanding benefits and salary compensation above the NIH scale
  • Generous relocation assistance and free on-campus parking

 

 

MORE ABOUT JAX

 

JAX began in 1929 with a small group of scientists dedicated to the emerging field of genetics. We now have over 1,700 scientists, technicians, and support staff, including over 50 Principle Investigators in five primary disease areas: cancer, reproductive biology, immunology, metabolic processes and neuroscience. Our fundamental contributions to biomedical research include cancer genetics and establishing the mouse as the premier research animal model.

 

  • Uncover more of our historic milestones, including the 26 Nobel prizes associated with our research, resources, and education
  • Read our latest news & insights for a glimpse at how we’re impacting the future of biomedicine
  • Follow the progress we’re making on our quest to improve human health via our recent research highlights

 

 

EEO: All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.

 

Job Location
Farmington, Connecticut, United States
Position Type

Read the full job description

Postdoctoral Fellow Computational Genetics and Systems Biology

Date Posted:
5/16/2017

Jackson Labs

CT

Postdoctoral Associate - Carter Lab

Tracking Code
6325
Job Description

Postdoctoral Associate - Computational Genetics & Systems Biology

Dr. Gregory Carter, Principal Investigator

 

About The Jackson Laboratory for Genomic Medicine: Comprising 183,000 square feet of highly advanced, state-of-the-art laboratories and supporting facilities, JAX-GM is conveniently located midway between NYC and Boston, in the heart of Connecticut. JAX-GM is part of an exciting, internationally-recognized research and educational institution with unparalleled genomic resources and research support services.

 

About the position: We are seeking Postdoctoral candidates in computational genetics and systems biology to develop novel computational methods that derive biological models from large-scale genetic and genomics data. Successful candidates will join the laboratory of Dr. Greg Carter at the Jackson Laboratory for Genomic Medicine (JAX-GM) in Farmington, CT, which coordinates activities with Dr. Carter’s group at the Jackson Laboratory for Mammalian Genetics in Bar Harbor, ME.

 

The Carter Lab develops computational approaches to the genetics of complex diseases, with a particular focus on Alzheimer’s disease (AD) using both human and mouse genetic methodologies. As part of the IU/JAX Alzheimer’s Disease Precision Models Center, we integrate data from large-scale Alzheimer’s data resources (ADNI, ADSP, AMP-AD, etc) to prioritize candidate loci for genome editing in novel mouse models of AD. We then develop and apply methods to jointly analyze mouse and human phenotype data to understand AD pathology, identify potential disease biomarkers, and assess candidate therapies. Our goal is to combine the power of human and mouse genetics to accelerate the discovery of novel treatments for AD. Visit the Carter Lab online for more.

 

 

MINIMUM QUALIFICATIONS

 

  • PhD in quantitative biology or a similar discipline such as computer science, physics, or applied mathematics
  • Strong background in computational biology and statistical approaches to genomics and genetics
  • Expertise in scientific programming languages such as R or MatLab
  • Commitment to solving biological problems and communicating those solutions

 

 

In addition, JAX Postdoctoral Associates benefit from:

 

  • Research training and mentorship from award-winning faculty
  • Individualized career advising and a dedicated Postdoc Program Office
  • Superior scientific services and unparalleled mouse resources
  • A uniquely collaborative academic research environment
  • Guidance from JAX's Postdoctoral Training Committee to help you succeed
  • Professional skills workshops including JAX's holistic The Whole Scientist course
  • Free access to JAX’s world-renowned Courses & Conferences programs
  • Outstanding benefits and salary compensation above the NIH scale
  • Generous relocation assistance and free on-campus parking

 

 

MORE ABOUT JAX

 

JAX began in 1929 with a small group of scientists dedicated to the emerging field of genetics. We now have over 1,700 scientists, technicians, and support staff, including over 50 Principle Investigators in five primary disease areas: cancer, reproductive biology, immunology, metabolic processes and neuroscience. Our fundamental contributions to biomedical research include cancer genetics and establishing the mouse as the premier research animal model.

 

  • Uncover more of our historic milestones, including the 26 Nobel prizes associated with our research, resources, and education
  • Read our latest news & insights for a glimpse at how we’re impacting the future of biomedicine
  • Follow the progress we’re making on our quest to improve human health via our recent research highlights

 

 

EEO: All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.

Job Location
Farmington, Connecticut, United States
Position Type
Full-Time/Regular
 

Read the full job description

Postdoctoral Fellow RNA Biology and Cancer Biology

Date Posted:
5/16/2017

Jackson Labs

CT

Postdoctoral Associate - Anczuków Lab

Tracking Code
6168
Job Description

 

Postdoctoral AssociateRNA Biology & Cancer Research

Dr. Olga Anczuków, Principal Investigator

??

 

About JAX-GM: Comprising 183,000 square feet of highly advanced, state-of-the-art laboratories and supporting facilities, the brand new JAX-GM conveniently sits midway between NYC and Boston in the heart of Connecticut. JAX-GM is part of an exciting $1.1 billion venture between the state of Connecticut and The Jackson Laboratory, an internationally-recognized research and educational institution with unparalleled genomic resources and research support services.

 

About the position: We are looking for talented postdoctoral candidates interested in RNA biology and cancer research to join the lab of Dr. Olga Anczuków at JAX-GM. We investigate how misregulation of RNA splicing contributes to breast and ovarian cancer progression as well as drug resistance.

 

Our research uses large clinical datasets, 3D cell cultures, as well as patient-derived xenograft (PDX) models that recapitulate more closely the complexity and heterogeneity of the primary tumors. Our goals are (i) to uncover causal splicing alterations in metastatic and drug-resistant tumors; (ii) to define pathways that affect splicing regulation in normal and cancer cells, as well as during tissue development; and (iii) to identify splicing factors and splicing events which could be used as biomarkers to predict disease progression or drug-response, or as targets for RNA-based therapeutics. We are leveraging advances in next-generation RNA-sequencing to decipher the role of splicing alterations in cancer with the goal of developing novel therapeutic strategies for precision medicine.

 

For more, visit the Anczuków Lab online.

 

 

KEY RESPONSIBILITIES

 

  • Lead projects and conduct experiments
  • May contribute to training of graduate students
  • Collaborate with other labs
  • Present research at conferences
  • Write manuscripts and contribute to grant writing

 

 

REQUIRED SKILLS

 

  • Highly self-motivated
  • Ability to work in a team environment
  • Ability to acquire new skills rapidly
  • Strong written and communication skills

 

 

MINIMUM QUALIFICATIONS

 

Required

  • Ph.D. and/or M.D. degree
  • First-authored publication(s) in peer reviewed journals with impact factor > 4
  • Background in molecular biology, cell biology, biochemistry and/or genomics
  • Research experience in cancer or/and RNA biology

 

Preferred

  • Research experience in computational biology
  • Research experience with next-generation sequencing
  • Research experience with mammalian cell culture

 

How to apply: Submit the following material as a single file with your online application:

  • Updated CV with education, research experience, publications list including impact factors and citations, and technical skills
  • Cover letter discussing your interest in this position and long-term career goals
  • Names and contact information for 3 professional references
  • Copy of the most relevant publication

 

 

In addition, JAX Postdoctoral Associates benefit from:

 

  • Research training and mentorship from award-winning faculty
  • Individualized career advising and a dedicated Postdoc Program Office
  • Superior scientific services and unparalleled mouse resources
  • A uniquely collaborative academic research environment
  • Guidance from JAX's Postdoctoral Training Committee to help you succeed
  • Professional skills workshops including JAX's holistic The Whole Scientist course
  • Free access to JAX’s world-renowned Courses & Conferences programs
  • Outstanding benefits and salary compensation above the NIH scale
  • Generous relocation assistance and free on-campus parking

 

 

MORE ABOUT JAX

 

JAX began in 1929 with a small group of scientists dedicated to the emerging field of genetics. We now have over 1700 scientists, technicians, and support staff, including over 50 Principle Investigators in five primary disease areas: cancer, reproductive biology, immunology, metabolic processes, and neuroscience. Our fundamental contributions to biomedical research include cancer genetics and establishing the mouse as the premier research animal model.

 

  • Uncover more of our historic milestones, including the 26 Nobel prizes associated with our research, resources, & education
  • Read our latest news & insights for a glimpse at how we’re impacting the future of biomedicine
  • Follow the progress we’re making on our quest to improve human health via our recent research highlights

 

 

EEO: All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.

Job Location
Farmington, Connecticut, United States
Position Type
Full-Time/Regular

Read the full job description

Postdoctoral Fellow 3D Chromatin Genomics

Date Posted:
5/16/2017

Jackson Labs

CT

Postdoctoral Associate – 3D Chromatin Genomics - Wei Lab

Tracking Code
5879
Job Description

 

Postdoctoral Associate3D Chromatin Genomics

JAX 4D Nucleome Center | Supervisor: Dr. Chia-Lin Wei

??

 

About JAX-GM: Comprising 183,000 square feet of highly advanced, state-of-the-art laboratories and supporting facilities, the brand new JAX-GM conveniently sits midway between NYC and Boston in the heart of Connecticut. JAX-GM is part of an exciting $1.1 billion venture between the state of Connecticut and The Jackson Laboratory, an internationally-recognized research and educational institution with unparalleled genomic resources and research support services.

 

About the JAX 4D Nucleome Center: Investigators at the JAX 4D Nucleome Center at JAX-GM have pioneered technologies for the genome-wide profiling of chromatin interactions. Although the genome is typically thought of as a linear sequence, it is actually a dynamic three-dimensional structure. Gene loci and regulatory elements that are linearly distant—or even on separate chromosomes—may be brought in spatial proximity, and such interactions are of fundamental importance for understanding genome regulation. The ultimate goal of the JAX 4D Nucleome Center is to deliver a Nucleome Positioning System for the generation of complex chromatin interaction network maps in the context of 3D genome structures. Such maps will be used to monitor and reference the dynamics of individual genomic elements, providing context to better understand gene function and the effects of genetic variation on gene function. The scientific team is led by Yijun Ruan, Chia-Lin Wei, Jeff Chuang, and Duygu Ucar.

 

About the position: The JAX 4D Nucleome Center is seeking enthusiastic, highly-skilled computational and experimental postdocs to develop computational and genomic approaches for understanding 3D genome biology under the light of diverse genomic and genetic information. Working under the supervision of Principal Investigator Chia-Lin Wei, successful applicants to this position will be developing projects aligned with Dr. Wei’s research focus. For details about Dr. Wei’s areas of focus, visit her Faculty page.

 

 

KEY RESPONSIBILITIES

 

The Center’s postdoctoral researchers will be generating and analyzing human chromatin interaction datasets in integration with other genomics and genetics datasets. We are seeking self-motivated, independent individuals who are interested in building their own career paths; however, postdoctoral fellows are expected to coordinate with and report to the PI responsible for the research areas addressed by their project.

 

The fellows will develop research projects in one or more areas of focus:

  • ?3D genome mapping and imaging technologies
  • Application of nano-engineering toward genomic methodologies
  • Computational modeling of 3D genome architectures
  • Building regulatory networks at multiple layers including gene expression, epigenetic, and chromatin data
  • Integrating regulatory interactions with genetic data
  • Mining and aligning chromatin interaction datasets in diverse human cell types
  • Functional perturbation of topological elements

 

 

REQUIRED SKILLS & QUALIFICATIONS

 

The JAX 4D Nucleome Center is interdisciplinary and collaborative, and preference will be given to individuals with experience working in such an environment.

 

For computational postdocs desired attributes include:

  • Familiarity with next generation sequencing data sets and pre-processing
  • PhD in a statistics/biostatistics or another computational field (CS, EE, Physics) with a strong foundation in statistics and data analyses
  • Excellent programming skills, preferentially with expertise in R and/or python and UNIX programming
  • Familiarity with network building, mining, alignment algorithms
  • Familiarity with bioinformatics resources, i.e., UCSC genome browser, NCBI

 

For experimental postdocs desired attributes include:

  • Strong problem-solving skills, creative thinking, and enthusiastic about science
  • Familiarity with next generation sequencing data sets and data generation
  • PhD in a genomics/genetics/biology or another relevant field
  • Excellent communication skills and fully fluent spoken and written English
  • Expertise in cellular and molecular biology techniques

 

 

In addition, JAX Postdoctoral Associates benefit from:

 

  • Research training and mentorship from award-winning faculty
  • Individualized career advising and a dedicated Postdoc Program Office
  • Superior scientific services and unparalleled mouse resources
  • A uniquely collaborative academic research environment
  • Guidance from JAX's Postdoctoral Training Committee to help you succeed
  • Professional skills workshops including JAX's holistic The Whole Scientist course
  • Free access to JAX’s world-renowned Courses & Conferences programs
  • Outstanding benefits and salary compensation above the NIH scale
  • Generous relocation assistance and free on-campus parking

 

 

MORE ABOUT JAX

 

JAX began in 1929 with a small group of scientists dedicated to the emerging field of genetics. We now have over 1700 scientists, technicians, and support staff, including over 50 Principle Investigators in five primary disease areas: cancer, reproductive biology, immunology, metabolic processes, and neuroscience. Our fundamental contributions to biomedical research include cancer genetics and establishing the mouse as the premier research animal model.

 

  • Uncover more of our historic milestones, including the 26 Nobel prizes associated with our research, resources, & education
  • Read our latest news & insights for a glimpse at how we’re impacting the future of biomedicine
  • Follow the progress we’re making on our quest to improve human health via our recent research highlights

 

 

EEO: All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.

Job Location
Farmington, Connecticut, United States
Position Type
Full-Time/Regular
 

Read the full job description

Postdoctoral Fellow Human Genomics

Date Posted:
5/16/2017

Jackson Labs

CT

Postdoctoral Associate - Lee Lab

Tracking Code
6378
Job Description

Postdoctoral Associate

 

 

About The Jackson Laboratory for Genomic Medicine: Comprising 183,000 square feet of highly advanced, state-of-the-art laboratories and supporting facilities, JAX-GM is conveniently located midway between NYC and Boston, in the heart of Connecticut. JAX-GM is part of an exciting, internationally-recognized research and educational institution with unparalleled genomic resources and research support services.

 

About the position: As a Postdoctoral Associate at The Jackson Laboratory, you will join a respected and growing scientific enterprise with eight decades of distinguished research in mammalian genetics and a promising future in genomic medicine. Your research will contribute to our important mission of discovering precise genomic solutions for disease and empowering the global biomedical community in our shared quest to improve human health.  

 

 

Our Postdoctoral Associates enjoy distinct advantages, including:

 

  • A uniquely collaborative environment that fosters interdisciplinary “team science” without departmental barriers
  • Unparalleled genomic resources and superior research support services
  • Close interaction with our award-winning faculty members
  • Partnerships with leading universities and medical centers
  • Numerous courses and conferences focused on genetics, genomics and biomedicine
  • Exceptional benefits, ample time off and other valuable programs
  • Working for an institution that has repeatedly been voted among the top 15 “Best Places to work in Academia” in the world by readers of The Scientist

 

 

MINIMUM QUALIFICATIONS

 

  • PhD (or nearing completion of PhD degree)
  • Background in human genetics or genomics and disease research
  • Publications (1st author highly advantageous)

 

 

MORE ABOUT JAX

 

The Jackson Laboratory began in 1929 with a small group of scientists dedicated to the emerging field of genetics. We now have over 1,700 scientists, technicians, and support staff, including over 50 Principle Investigators in five primary disease areas: cancer, reproductive biology, immunology, metabolic processes and neuroscience. Our fundamental contributions to biomedical research include cancer genetics and establishing the mouse as the premier research animal model.

 

  • Uncover more of our historic milestones, including the 26 Nobel prizes associated with our research, resources, and education
  • Read our latest news & insights for a glimpse at how we’re impacting the future of biomedicine
  • Follow the progress we’re making on our quest to improve human health via our recent research highlights

 

 

EEO: All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.

Job Location
Farmington, Connecticut, United States
Position Type
Full-Time/Regular
 

Read the full job description

Postdoctoral Fellow Precision Genomics

Date Posted:
5/16/2017

Jackson Labs

CT

Postdoctoral Associate - Robinson Lab

Tracking Code
6214
Job Description

Postdoctoral Associate

 

About JAX-GM: Comprising 183,000 square feet of highly advanced, state-of-the-art laboratories and supporting facilities, the brand new JAX-GM conveniently sits midway between NYC and Boston in the heart of Connecticut. JAX-GM is part of an exciting $1.1 billion venture between the state of Connecticut and The Jackson Laboratory, an internationally-recognized research and educational institution with outstanding genomic resources and research support services.

 

About the position: As a Postdoctoral Associate at The Jackson Laboratory, you will join a respected and growing scientific enterprise with eight decades of distinguished research in mammalian genetics and a promising future in genomic medicine. Your research will contribute to our important mission of discovering precise genomic solutions for disease and empowering the global biomedical community in our shared quest to improve human health.  

 

 

KEY RESPONSIBILITIES

 

  • Algorithm development for genomics data including especially transcriptomics next-generation sequencing data generated by various platforms
  • Algorithm development for the integrative analysis of splicing and alternative splicing
  • Development of robust software to implement the algorithms including unit testing, versioning, sufficient documentation, and user manuals
  • Comparison of algorithm performance on biological datasets from JAX and other groups, participation in scientific projects within the Robinson group on relevant genomics topics
  • Presentation of results at scientific meetings and participation in manuscript and grant writing

 

 

MINIMUM QUALIFICATIONS

 

  • PhD (or nearing completion of PhD degree)
  • Background in human genetics or genomics and disease research
  • Publications (1st author highly advantageous)
  • Skills in computer programming using compiled languages such as C/C++ or Java, and at least one scripting language such as Perl or Python. Experience with statistical software such as R would be considered an advantage.

 

 

In addition, JAX Postdoctoral Associates benefit from:

 

  • Research training and mentorship from award-winning faculty
  • Individualized career advising and a dedicated Postdoc Program Office
  • Superior scientific services and unparalleled mouse resources
  • A uniquely collaborative academic research environment
  • Guidance from JAX's Postdoctoral Training Committee to help you succeed
  • Professional skills workshops including JAX's holistic The Whole Scientist course
  • Free access to JAX’s world-renowned Courses & Conferences programs
  • Outstanding benefits and salary compensation above the NIH scale
  • Generous relocation assistance and free on-campus parking

 

 

MORE ABOUT JAX

 

JAX began in 1929 with a small group of scientists dedicated to the emerging field of genetics. We now have over 1,700 scientists, technicians, and support staff, including over 50 Principle Investigators in five primary disease areas: cancer, reproductive biology, immunology, metabolic processes and neuroscience. Our fundamental contributions to biomedical research include cancer genetics and establishing the mouse as the premier research animal model.

 

 

  • Uncover more of our historic milestones, including the 26 Nobel prizes associated with our research, resources, and education
  • Read our latest news & insights for a glimpse at how we’re impacting the future of biomedicine
  • Follow the progress we’re making on our quest to improve human health via our recent research highlights

 

EEO: All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.

 

 

Job Location
Farmington, Connecticut, United States
Position Type
Full-Time/Regular
 

Read the full job description

Postdoctoral Fellow Stem Cell Biology and Cancer Epigenetics

Date Posted:
5/16/2017

Jackson Labs

ME

Postdoctoral Associate - Stem Cell Biology and Cancer Epigenetics

Tracking Code
4985
Job Description

An academic postdoctoral associate position is available in the laboratory of Dr. Jennifer Trowbridge to study epigenetic mechanisms governing hematopoietic stem cell lineage commitment, and how deregulation of epigenetic modifications leads to myeloproliferative disorders including leukemia (http://trowbridgelab.com).


The Jackson Laboratory (JAX) offers a unique research and training environment characterized by multidisciplinary scientific collaboration, unparalleled mouse resources, outstanding core services, and is located adjacent to Acadia National Park in coastal Maine. Translational research collaborations in genomics-based, personalized medicine are fostered through our new JAX Genomic Medicine campus in Farmington, CT. In addition to lab-based training, JAX has developed a unique program for trainees to expand their professional skills in science communication, entrepreneurship, teaching, mentoring and laboratory management to best prepare postdocs for future career opportunities.

Required Skills

Ability to plan, execute and analyze an independent research project as well as exceptional verbal and written communication skills. Preference given to self-motivated and career oriented individuals.

Required Experience

A Ph.D. in biological or related sciences is required, and a strong training background in molecular biology, cell biology and/or epigenetics is preferred.


Apply by submitting a cover letter describing past research accomplishments, research interests and career aspirations, a current CV, and the names of three references, as one PDF file.

 

 

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.

 

Job Location
Bar Harbor, Maine, United States
Position Type
Full-Time/Regular
Salary
50,000.00 - 70,000.00 USD

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Postdoctoral Fellow Cell Polarity and Development of the Inner Ear

Date Posted:
5/16/2017

Jackson Labs

ME

Postdoctoral Associate – Cell Polarity and Development of the Inner Ear

Tracking Code
6256
Job Description

 

The Tarchini Lab at The Jackson Laboratory is seeking a Postdoctoral Associate to investigate cell polarity and morphogenesis in the inner ear. Our projects exploit mouse genetics, somatic gene transfer and organotypic culture to study the molecular mechanisms that polarize sensory hair cells during development (http://tarchini-lab.org). We are especially interested in dissecting how G protein signaling controls and coordinates two features essential for hearing and balance ability: 1) the striking alignment of hair cells along the epithelial plane (planar polarity), and 2) the staircase-like architecture of the motion-sensor compartment of hair cells, the stereocilia bundle.

 

 

The Jackson Laboratory (http://www.jax.org) in Bar Harbor, Maine, USA, is recognized internationally for its excellence in research (e.g. The Nathan Shock Aging Center and Center for Novel Alzheimer’s Disease Models), unparalleled mouse resources, outstanding training environment characterized by scientific collaboration, and exceptional core services - all within a spectacular setting adjacent to Acadia National Park. Translational research collaborations in genomics-based, personalized medicine are fostered through our JAX Genomic Medicine campus in Farmington, CT. In addition to lab-based training, JAX has developed a unique program for trainees to expand their professional skills in science communication, entrepreneurship, teaching, mentoring and laboratory management to best prepare postdocs for future career opportunities.

 

Required Skills

 

Ability to plan, execute and analyze an independent research project is essential, as well as exceptional verbal and written communication skills. Preference will be given to self-motivated and career oriented individuals.

 

Required Experience

Required qualifications include a recently obtained PhD or MD in Developmental or Cell Biology, Neuroscience or a related field, and a genuine commitment to solving biological problems. Expertise with inner ear Biology, mouse genetics and fine dissection is desired but not required. 

Job Location
Bar Harbor, Maine, United States
Position Type
Full-Time/Regular
Salary
50,000.00 - 70,000.00 USD

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System Genetics Alzheimer's and Aging

Date Posted:
5/16/2017

Jackson Labs

ME

Postdoctoral Associate - Systems Genetics of Aging and Alzheimer's Disease

Tracking Code
6237
Job Description

 

The Kaczorowski Lab at The Jackson Laboratory is seeking a Postdoctoral Associate in systems genetics of aging and Alzheimer’s disease. Projects exploit genetically diverse mouse populations to identify and link novel risk and protective variants to molecular, cellular and circuit level mechanisms using state-of-the-art genomic sequencing, proteomics and in vivo electrophysiology in freely moving mice. We are especially interested in dissecting how genetic and environmental factors influence the onset and progression of disease, determine resilience, and translate to humans.

 

 

The Jackson Laboratory (http://www.jax.org) in Bar Harbor, Maine, USA, is recognized internationally for its excellence in research (e.g. The Nathan Shock Aging Center and Center for Novel Alzheimer’s Disease Models), unparalleled mouse resources, outstanding training environment characterized by scientific collaboration, and exceptional core services - all within a spectacular setting adjacent to Acadia National Park. Translational research collaborations in genomics-based, personalized medicine are fostered through our JAX Genomic Medicine campus in Farmington, CT. In addition to lab-based training, JAX has developed a unique program for trainees to expand their professional skills in science communication, entrepreneurship, teaching, mentoring and laboratory management to best prepare postdocs for future career opportunities.

 

 

Exceptional postdoctoral candidates will have the opportunity to apply to become a JAX Postdoctoral Scholar, a selective award addressing the national need for research scientists who are accomplished in the broadly defined fields of genetics and genomics. The award includes an independent research budget, travel funds, and a salary above standard postdoctoral scale.

 

Required Skills

Ability to plan, execute and analyze an independent research project as well as exceptional verbal and written communication skills. Preference given to self-motivated and career oriented individuals. 

Required Experience

 

Required qualifications include a PhD or MD in Neuroscience or a related field and a commitment to solving biological problems. Expertise in scientific programming languages including R, C/C++, Ruby, Perl, or Java is recommended. Expertise in neurological disease is desired but not required.

 

Job Location
Bar Harbor, Maine, United States
Position Type
Full-Time/Regular
 

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Postdoctoral Fellow

Date Posted:
5/16/2017

Janssen

PA

Job Description

Requisition ID: 1106170514

Summary:

The scientist candidate will be responsible for studying mechanisms, pathways, and therapies associated with cancer immunology.

 

Job description:

We are seeking a highly motivated Postdoctoral Researcher to join our group at Janssen RND for 2 years. The candidate will join the Discovery Sciences Department research efforts in the characterization and development of therapeutics for the treatment of cancer. His/her responsibilities will include the design, execution and interpretation of studies for the validation and characterization of new targets and therapeutic agents.

He/she will be part of an extended team driving research on pre-clinical target identification/target validation and drug development in collaboration with our Oncology Discovery Department. He/she will explore mechanisms that enhance anti-tumor immunity and cause tumor cell killing, using primarily human and mouse tumor models and in vitro assays. Additionally, the candidate will explore underlying mechanisms of autoimmunity/immune tolerance, neo-antigen presentation, and regulation of immune activation (e.g. DCs, Tregs, T effector, T memory, and myeloid-derived suppressor cells).

 

The candidate will be responsible for isolating a variety of primary immune cell sub-types from human, rodent, and non-human primate products for in vitro and in vivo use in a BSL-2 environment. The ideal candidate will have a deep knowledge of flow cytometry, cell culture, and immune cell assays. Expertise in cell sorting, and retroviral/lentiviral infections is preferred.  Knowledge in cancer immunology or the biology of T cells/ myeloid cells in autoimmunity is strongly preferred.

 

The candidate will work with key partners to generate target identification and validation data using omics and functional genomics approaches combined with in vitro cell based and mouse models.  He/she will use gene editing tools such as CRISPR to investigate immune cell/target cell regulation and differentiation and to explore the impact of neo-antigens in disease.  The candidate will be responsible for authoring papers documenting the work and giving presentations at appropriate conferences. The scientist will effectively and frequently collaborate with colleagues in the oncology department as well as in the medicinal chemistry and antibody development groups as needed, as well as present scientific results to multidisciplinary teams.

 
 

Primary responsibilities (include, but are not limited to):

  • Demonstrate ability to design, perform and interpret complex in vitro, ex vivo and in vivo experiments
  • Proficiency in Flow Cytometry assays and immune cell isolation from whole blood or tissues and cell culture is required
  • Proficiency in cell biology assays that could include multi-parameter FACS, ELISAs, cell proliferation, cellular cytotoxicity, antigen immunogenicity   are desirable
  • Demonstrate the ability to analyze and present data in professional 'publication ready' format
  • Demonstrate the ability to work independently and manage multiple experiments simultaneously
  • Demonstrate the ability to contribute to various projects outside of his/her own, and collaborate with stakeholders from all relevant functions
  • Previous experience with IC50 determination, kinase assays, MesoScale, AlphaLISA, Luminex is desirable.
  • Keep up-to-date with the literature related to his/her field.
  • Demonstrate clear and professional verbal and written communication. The candidate must maintain written record of studies in the form of electronic records including notebooks, technical reports, summaries, and protocols. Once fully trained, the successful candidate will be able to work independently and manage time based on department priorities.


Qualifications
Qualifications:
  • Education: The ideal candidate will have a Ph.D. in cell biology, immunology or a related discipline.
 
  • Related Experience: Strong cell biology and assay development skills are required. Knowledge of flow cytometry, cell culture, and immune cell assays is required. Experience in cancer immunology or the biology of T cells/ myeloid cells in autoimmunity is strongly preferred. A good background in cancer biology is desirable.
 
  • Personal skills and Competencies:
    • Intellectually curious and well informed on the latest scientific advances in the field
    • Demonstrated creativity and novel approaches to solving scientific problems
    • Excellent interpersonal skills with the ability to interact effectively with people, internally and externally
    • Detail-oriented, with excellent organizational and record-keeping skills
    • Excellent oral and written communication skills. Able to effectively present scientific data and concepts to international standards. 

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Science Policy Fellowship

Date Posted:
5/16/2017

National Center for Health Research

DC

National Center for Health Research FELLOWSHIPS
6-Month and 12-Month Fellowship Positions open at National Center for Health Research with Opportunity for Renewal or Advancement
OLYMPUS DIGITAL CAMERA
Senior Fellow: 
Terrific opportunity for someone with a PhD or MD or similar doctorate who recently completed their degree or post-doc or wants to move into the policy arena. We are seeking an experienced professional with expertise in quantitative research who can interpret and “translate” research findings into compelling and persuasive information for the public, policy makers, and potential funders. A doctorate in epidemiology/public health, medicine, psychology, or closely related field is required. Excellent oral and written communication skills are required.  Grant-writing skills are a plus. $45,000-50,000/year plus benefits for full-time work for candidate with a doctorate or medical degree (must be at least 32 hours per week).
Apply now for a Fellowship beginning in May or June 2017.  Send a resume and cover letter to Amelia Murphy at aam@center4research.org. For more information about our Center, see www.center4research.org and www.stopcancerfund.org. For more information about our policy work, see the policy and media sections of those websites.  No calls please.
Fellow:  An MPH or ABD
An MPH or ABD in epidemiology/public health, psychology, or closely related field is required. Other skills as described above.  The starting salary is $35,000-40,000/year for a full-time position.
Learn first-hand about the Washington policy scene by gaining hands-on experience! We are a non-profit think tank that makes a difference in the lives of millions of adults and children. We work closely with the national and international media to get our message out to the public. We connect with policy makers and decision makers on a national level to change public policy. We work with independent researchers from around the country to bring fair, unbiased and non-corporate-funded information to the public about timely health issues such as the safety of medical products and treatments, dating violence, women’s health, affordable health care, and so much more.
The ideal candidate will be attentive to details, well-organized, dedicated to health issues, have excellent oral and written communication skills, and work well individually and as part of a team.  Preference will be given to candidates with the ability to critique quantitative research data on medical or public health issues and to explain it in an interesting way to a lay audience. This is a part-time (at least 32 hours/week) or full-time 6-month position, eligible for renewal or promotion after 6 months.  Our office is a few blocks from the White House.
We will fill this position asap, so do not apply if you are not available soon. To learn more about us, check out www.center4research.org and www.stopcancerfund.org. No calls please. Please send your resume and cover letter describing how your interests and expertise fits our work as soon as possible to info@center4research.org.  Include your available starting date and numbers of hours per week in your cover letter. Please note: this is not a telecommuting position.

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Tenure Track Faculty Neuroscience Initiative

Date Posted:
5/14/2017

CUNY

NY

The Neuroscience Initiative of the CUNY Advanced Science Research Center in Manhattan, NY, invites applications for full-time, tenure-track faculty members at the Assistant, Associate or Full Professor rank.

We seek outstanding scientist with a strong record of publications and significant research accomplishments in the fields of: glial biology, glial-neuronal communication, brain metabolism, gut/brain communication, environmental effects on brain structure and brain metabolism and studies integrating Nanotechnology and Photonics with Neuroscience.

We also encourage candidates with a background in analysis of large data set, such as genome-wide distribution of Epigenomic marks (i.e. ChIP, ATAC-Seq, RNA Seq, DNA methylation), analysis of Microbiome data sets and integration with Metabolomic approaches, to apply. Experience with Network Analysis and Large data integration applied to biological questions is required.

We encourage application from candidates with a collaborative spirit and passion for education, proposing innovative ideas and interdisciplinary approaches, with a demonstrated use of a wide range of experimental and computational approaches to tackle fundamental questions in neurobiology.

Candidates for Assistant Professor positions are expected to have advanced degrees (Ph.D., M.D. or equivalent) in any area of biology, neuroscience or computation plus at least 3 years of postdoctoral research experience in the indicated fields of research.  At Associate and Full Professor level, faculty ranks will be determined based on: overall qualifications, scholar contributions (as per publications and funding record) and demonstrated commitment to conducting high-level scientific research adopting interdisciplinary approaches.  Individuals considered for these positions are expected to serve a major role in shaping an outstanding research mission at the ASRC, while fulfilling the educational mission of the New York City Public University System at CUNY.

Opened in Fall 2014, the 200,000 ft2 CUNY ASRC offers a highly interactive and collaborative environment that integrates five disciplines: Neuroscience, Photonics, Structural Biology, Nanoscience and Environmental Sciences.  Combining world-class experts in these areas with state-of-the-art instrumentation both in the building and within the New York City area, the ASRC offers a unique opportunity for new research programs to flourish and bridge conceptual gaps among traditionally disparate scientific areas.

Applicants should electronically submit 1) a curriculum vitae, 2) a 1-2 page cover letter summarizing research accomplishments and views on interdisciplinary research and 3) a brief (3 page max) description of proposed research. The names and contact information of 3 references should be listed on the application. Please submit all the material to the Neuroscience Initiative Search Committee c/o Kevin Wang, at Academic Jobs Onlinehttps://academicjobsonline.org/ajo/jobs/9095, Job# 9095.  The first review of the applications is expected to be completed by August 31, 2017, but the search will remain open until all the available positions are filled.


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Senior Scientist HLA immunopeptidomics LC-MS

Date Posted:
5/14/2017

Pfizer

MA

We are seeking a Senior Scientist to develop and apply advanced mass spectrometry techniques to measure HLA-associated peptidomes. The position is integrated into a multidisciplinary group dedicated to understanding and predicting the immunogenicity of protein-based therapeutics. The successful candidate will closely work together with cellular biologists and quantitative protein mass spectrometrists to establish the utility of a dendritic cell mass spectrometry (DC-MS) assay. This assay detects peptides from therapeutic proteins that are processed and presented on MHC (major histocompatibility complex) class II by dendritic cells for helper CD4+ T cell recognition. In addition to MHCII immunoaffinity isolation and mass spectrometry analysis of isolated peptides, this position requires expertise in relevant bioinformatics solutions to mine the data for confident identification of peptide presentation. Alongside the application of the tool to our protein therapeutics portfolio, the candidate in this position will work to further refine the technique. The Senior Scientist will join at the interface of predictive immunogenicity sciences and leading protein mass spectrometry to become a key contributor to our efforts to rationally design low immunogenicity biomolecules.



Responsibilities

*Responsible for the set-up, advancement and application of the dendritic cells mass spectrometry (DC-MS) assay with particular focus on MHCII immunoaffinity procedures, high resolution LC-MS/MS analysis and bioinformatics.

*As a strong collaborator develop deep partnerships with Immunogenicity Scientists working on cell preparation or assessing immunogenicity project risks as well as other LCMS team members.

*Participate and lead in technology development and implementation by exploring advancement to the DC-MS workflow.

*Participate in all phases of mass spectrometry laboratory operations including technology evaluations, the development of sample preparation and separation methods, data analysis, interpretation, reporting and follow up discussions with the project teams on utilizing the data in appropriate decision making.

*Ensure all tasks and responsibilities are carried out according to scientific and ethical standards e.g. responsible for eWorkbook record keeping.

*Publications in peer-reviewed scientific journals and external / internal presentations are expected.

Requirements

Qualifications

*Qualified applicants hold a Ph.D. ideally plus several years of post-doctoral experience or related degree with equivalent years of experience.

 

*Expertise in development and implementation of mass spectrometry based immunopeptidomics methods.

*Expertise in mass spectrometry based proteomics.

*Experience and knowledge in operation of QExactive mass spectrometers and associated control and data analysis software systems.

*Knowledge and application of complex sample preparation methodologies as applied to quantitative protein mass spectrometry workflows techniques including immuno-analytical techniques.

*Good understanding of protein biochemistry. PHYSICAL/MENTAL REQUIREMENTS As appropriate for lab based role. NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

*Lab based position requiring to perform all typical laboratory related activities

*Based in Andover

*Occasional travel to Cambridge (Kendall Square) is required, depending on project needs

 


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Image Analysis Scientist

Date Posted:
5/14/2017

Advanced Cell Diagnostics

CA

Advanced Cell Diagnostics, Inc. (ACD) is a leader in the field of molecular pathology and tissue-based diagnostics. Our core RNAscope® technology is the world’s first multiplex fluorescent and chromogenic insitu hybridization platform capable of detecting and quantifying RNA biomarkers in situ at single molecule sensitivity. RNAscope® is an ideal platform for developing the next generation of tissue-based companion diagnostics. We are committed to continued innovation to bridge the gap between basic research and clinical medicine to fulfill the promise of personalized medicine.

RNAscope RNA ISH assays generate high quality microscopic images of RNA expression and localization with detailed morphological context, enabling integrative analysis of quantitative biomarker expression and morphological features at single cell resolution.  We are looking for a highly motivated and creative scientist with a background in biological image analysis software to join our R&D team. You will be responsible for developing software solutions customized for extracting and interpreting data from RNAscope-generated images.

Duties and Responsibilities

•Research and evaluate image analysis software and algorithms
•Perform image analysis using software algorithms
•Collaborate with third party image analysis software developers
•Develop custom software  solutions for detecting and quantifying signals in RNAscope images
•Validate and transfer software solutions to Pharma Service Assays (PAS) group
•Train and support PAS for optimal use of software solutions for client projects

Requirements


•PhD or MS or BS in biological sciences, biomedical engineering, computational biology, bioinformatics or a related field
•Experience in image-based data analysis using image analysis software
•Knowledge of image analysis algorithms  and software
•Programming experience in C, C++, Java, MATLAB, R or scripting languages a plus
•Experience in immunohistochemistry, immunofluorescence, or in situ hybridization a plus
•Strong organizational and interpersonal skills
•Strong written and verbal communication skills


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Contract Specialist - Temporary

Date Posted:
5/14/2017

Vertex

CA

Vertex Pharmaceuticals is looking for a Temporary Contract Specialist to join our Research Contracts and Collaborations group in San Diego. The Temporary Contract Specialist will be responsible for the completion of Confidential Disclosure, Consulting, Material Transfer and other agreements associated with Vertex's external global research efforts. This individual will participate in the generation of the agreements using legal templates, negotiate terms and conditions with for-profit and non-profit groups (academic laboratories, university technology transfer offices, CROs, etc.), produce progress reports and coordinate final execution of the agreements. The Temporary Contract Specialist will work closely with the Legal department, the Accounting/Finance Department, the Research Contracts and Collaborations group and the Vertex research community. This position may be required to work under tight timelines.

Day to day duties include:

  • Drafting and negotiation of various agreements using legal templates
  • Interfacing internally and externally with various parties to negotiate and finalize agreements
  • Keep track of terms and issues of agreements
  • Entering agreements and associated data into a contracts database and financial management system, with careful attention to tracking the progress of in-progress agreements
  • Keep updated files and prepare reports as required

Minimum Qualifications:

  • Bachelor’s Degree with a major in the life sciences, chemistry, or pharmaceutical sciences.
  • Excellent verbal and written communication skills
  • Strong negotiation and organizational skills and attention to detail.
  • Proficient with standard office software applications (MS Excel/Word/PowerPoint)
  • Ability to work well independently and with others
  • Effective cross-disciplinary communication skills and an eagerness to creatively engage the Vertex legal team, scientists, and business leaders to fully understand complex issues and craft innovative solutions
  • The intellectual curiosity and drive to offer comprehensive solutions to the team, consisting of Scientists, Finance and Legal representatives, etc., to ensure the successful organization of our research agreements
  • Demonstrated ability to work successfully in a fast paced environment

Preferred Requirements:

  • Experience in academic technology transfer offices or pharmaceutical/biotech companies are preferred
  • Contracts management experience highly desirable
  • Experience working with external groups towards a goal where timeliness are met or exceeded on a regular basis

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Associate Licensing and Business Development

Date Posted:
5/14/2017

Wistar Institution

PA

The Wistar Institute is seeking a Licensing and Business Development Associate to proactively build and expand Wistar relationships with industry, non-profit, and other academic partners to enhance the value of Wistar intellectual property assets and increase research funding support.

 

This hire will work closely with all Wistar research investigators to provide the highest quality of customer-service and consulting services oriented around intellectual property protection, technology development, licensing, sponsored research, and securing alternative sources of research funding support. Additionally, the Licensing and Business Development Associate will identify projects of commercial interest, facilitate the establishment of research collaborations with industry, and negotiate licenses for intellectual property with established and startup companies.

 

Education: Ph.D. /M.D. in a biomedical science preferred.

 

Experience: 1-2 years related experience in university-industry technology transfer is preferred. Exceptional customer-service skills are needed, along with experience managing a large, diverse set of tasks and projects. Excellent time management and prioritization skills also required. Candidate must be a proactive, independent self-starter with strong work ethic. Team player who embraces quality and accurate work product. Strong attention to details, follow-through and closing.

 

The Wistar Institute is located in the University City area of Philadelphia, in the heart of the University of Pennsylvania Campus. Wistar provides resources to its faculty and staff that enable them to conduct cutting edge collaborative research and provides for outstanding intellectual environments and state-of-the-art facilities. Research discoveries conducted at Wistar have led to the development of vaccines; the identification of genes associated with cancers; and the development of many other significant research technologies and tools.


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Scientist Therapeutic Antibody Discovery

Date Posted:
5/14/2017

Amgen

INT

Amgen is a leading global biotechnology company, with a mission to serve patients around the world. As a science-based, patient-focused organization, we discover and develop innovative therapies to treat serious illnesses. Our medicines have made a dramatic difference in the lives of millions.

Amgen British Columbia, located in Metro Vancouver, Canada, is a research center of excellence focused primarily on the use of XenoMouse® technology for the discovery of fully human therapeutic monoclonal antibodies. This team is seeking a highly motivated and experienced researcher to help us advance our therapeutic antibody discovery efforts.

The incumbent will complement an innovative group with a strong track record of success in pioneering novel antibody-based therapeutics to treat grievous illnesses. The role will be laboratory-based, supporting multiple diverse therapeutic discovery programs, in addition, to bringing forward crucial new concepts and techniques to identify therapeutic candidates with extreme functional design goals.

An essential part of this role is a demonstrated competency with in vitro selection technologies such as Phage display, Yeast display or Mammalian display with fundamental scientific strengths in protein biochemistry, molecular biology and cell biology.  This role will also be involved in assay development and design, scientific analysis, problem solving and creativity.

Canadian and international applicants will be considered.

 

Requirements

Basic Qualifications

 

PhD in a scientific discipline
OR
Master's degree in a scientific discipline and 4 years of scientific experience
OR
Bachelor's degree in a scientific discipline and 6 years of scientific experience

2 years' experience in one or more antibody discovery technologies (e.g. hybridoma, phage display, B cell recovery (SLAM), nanoscale screening, gel microdrop, NGS, etc.)
Assay development supporting large molecule screening

Preferred Qualifications

  • Knowledge of FACS based binding assays and analysis
  • 3+ years' relevant post-doctoral research or equivalent industry experience in therapeutic antibody discovery field.
  • Proficiency in screening characterization platforms; Biacore, ForteBio, etc.
  • Large molecule discovery and development experience
  • Demonstrated Group management/leadership experience
  • Experience in a working environment requiring strong inter-personal and communication skills across a broad range of audiences including senior scientists and leaders throughout an organization
  • A consistent record of scientific achievement including innovation, collaboration and publication.
  • Experience in a role requiring strong problem solving and scientific skills
  • IP creation

Amgen endeavors to make its recruitment process accessible to any and all users. Reasonable accommodations will be provided, upon request, to applicants with disabilities in order to facilitate equal opportunity throughout the recruitment and selection process. Please contact to make a request and ensure you include the requisition number.

Reasonable accommodations are available, upon request, to facilitate the equal participation of candidates with disabilities, should you be selected for an interview.


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Scientist Protein Engineering

Date Posted:
5/14/2017

Zymeworks

INT

Job Description

-Performs research and feasibility studies into proposed protein-engineering projects.
-Designs expression constructs for antibody and protein production.
-Plans and develops purification and assay protocols.
-Participates in the development of plans, schedules and costs of assigned projects/programs.
-Liaises with laboratory personnel and CRO staff to follow-up on the protein expression and screening for biophysical and bioactivity of the engineered molecules.
-Prepares reports on assigned projects for internal and external use, makes presentations to team and contributes to technical journals.
-Participates in the preparation of patents and publications.
-Checks, organizes, analyzes and reports data produced. Prepares reports, documents and dossiers.
-Liaises with laboratory personnel and CRO staff to follow-up on the protein expression and screening for biophysical and bioactivity of the engineered molecules.
-Fosters effective and collaborative working relationships with fellow employees, management and external partners.

Requirements

-PhD in a scientific discipline (Biochemistry, Immunology, Molecular or Cellular Biology or related field), and a minimum of 2 to 5 years’ related experience (may include post-doctoral experience) or an equivalent combination of education and experience.
-Proven interpersonal skills with the ability to work collaboratively as a member of a cross-functional team. Ability to establish and maintain effective working relationships.
-Experience in protein expression, purification, biochemical and bioactivity characterization using techniques such as ELISA, SPR, FACS, etc.
-Experience in a least some important biophysical characterization techniques such as UPLC/SEC, DSC/DSF, AUC, DLS, LC-MS, etc.
-Understanding of protein chemistry and experience in rational protein design and engineering.
-Experience with molecular model building, simulation and visualizing packages (AMBER, CCP4, COOT, etc.)
-Meticulous organization, record keeping and reporting.
-Good analytical and problem solving skills, incorporating integrity in all decision making.
-Ability to manage concurrent deliverables and work effectively in a challenging, milestone-driven environment.
-Effective oral and technical/scientific writing skills. -Previous experience presenting scientific data to internal audiences.

Why Work for Us?

Zymeworks’ employees are passionate, engaged and extremely motivated to succeed. We are excited by the cutting-edge science and technology, the endless possibilities this union holds and the sheer opportunity to be a part of something big. To learn more about Zymeworks Inc. and our current openings, please visit our website at www.zymeworks.com.


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Post Doctoral Fellow Cell Based Assays

Date Posted:
5/14/2017

Turnstone Biologics

INT

Based in Ottawa, Turnstone Biologics (www.turnstonebio.com) have a number of exciting new Post-Doctoral Fellowship (PDF) opportunities.  The PDF’s will be responsible for design, execution and analysis of basic research projects that will support advancement of current and future Turnstone Biologics programs.  We are seeking highly motivated, independent individuals who are able to work in the collaborative environment of a small biotech company.

Responsibilities include but are not limited to:

•   Ability to multi-task and conduct multiple large experiments concurrently
•   Ensure research studies are completed at a high quality in the determined timeframe
•   Exquisite attention to detail demonstrated through extensive recording in laboratory notebooks
•   Report generation on all completed studies
•   Assist with regulatory document submission preparation as required
•   Other assigned duties and responsibilities as required.

Requirements

•   Recent PhD degree required in Immunology, Virology, Molecular Biology or related field
•   Preferably less than 5 years of previous post-doctoral training
•   Experience in: recombinant DNA cloning is considered an asset; cell based assays (microscopy, robotics, and/or automation experience); QA/QC validation; GMP/GLP procedures
•   Excellent written, oral and presentation communication skills
•   Strong ability to work closely with all disciplines within a small company, displaying innovative thinking, motivation and accountability
•   Ability to travel as required.


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Bioreactor Scientist

Date Posted:
5/14/2017

Duke

NC

The Duke Human Vaccine Institute (DHVI) and the Duke Center for HIV/AIDS Vaccine Immunology & Immunogen Discovery (CHAVI-ID), under the direction of Dr. Barton Haynes, providing national and international leadership in the fight against major infectious diseases, is currently recruiting for a highly motivated individual to join our GMP Process Development team. The Duke Human Vaccine Institute is an interdisciplinary, interdepartmental institute dedicated to the study of basic and translational science required to understand host-pathogen interactions that can be translated to vaccines against human diseases. We are a team of highly interactive investigators that have expertise in mucosal and systemic virology, immunology, molecular biology, microbiology and animal models.

The Bioreactor Scientist will work as part of the team to develop and optimize cell culture conditions to support GMP manufacturing of potential vaccine candidates. This role will conduct and document laboratory experiments focused on optimization of cell culture conditions for the production of recombinant vaccine candidates and the execution of GMP manufacturing lots in the DHVI production facility. Responsibilities will include experimental design, troubleshooting, analysis, maintenance of CHO cell cultures, preparation and operation of bioreactors, and will work closely with the down-stream processing team in supporting optimization of methods during process development by providing key analytical information regarding the quality of the potential vaccine product.
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Job Requirements


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The ideal candidate will have a Bachelor’s degree in biochemistry, engineering or other related scientific discipline. A related Masters or PhD is a plus. The ideal candidate will have experience with cell culture/fermentation process development and experience in operation of bioreactors.

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Postdoctoral Fellow Vaccine Research

Date Posted:
5/14/2017

Duke

NC

The Duke Human Vaccine Institute (DHVI), an international leader in the fight against major infectious diseases, is currently recruiting for Postdoctoral Associates to join our research team. The Duke Human Vaccine Institute is an interdisciplinary, interdepartmental institute dedicated to the study of basic and translational science required to understand host-pathogen interactions that can be translated to vaccines against human diseases. Directed by Dr. Barton Haynes, we are a team of highly interactive investigators that have expertise in immunology, molecular biology, virology, microbiology, computational biology, and vaccine science. We are seeking highly motivated recent PhD graduates (Immunology, Molecular Biology, Biochemistry, Biomedical Engineering, Computational Biology, Virology or related scientific field) to play an integral role in the following projects related to HIV/AIDS Vaccines and Cure research and identification of correlates of protection for other diseases such as malaria:

• Identification of protective B cell responses through evaluation of HIV immunogens in animal models and in human vaccines. (Dr. Barton Haynes)
• Interrogate the biophysical properties of antibody-antigen binding interactions to provide insights into the mechanisms of protective immunity for HIV-1, malaria and other pathogens. (Dr. Georgia Tomaras)
• Assessment of immune-based strategies for prevention of maternal and pediatrics HIV/AIDS. (Dr. Sallie Permar)
• Investigate the development of HIV antibodies by analyzing immune repertoire sequencing and computationally design immunogens for human vaccines (Dr. Kevin Wiehe)

The DHVI has a dynamic mentoring program, directed by Dr. Georgia Tomaras, and our postdoctoral associates work in concert with Duke faculty and staff in an invigorating research training environment. One of our chief scientific missions is to support and train early stage investigators to be the next generation of scientific leaders equipped to identify and implement solutions for improving human health worldwide.

DHVI functions as not-for-profit vaccine development biotechnology enterprise, embedded within a top university. As a trainee within our mentoring program, you will interact with highly innovative and collaborative investigators and have the opportunity to master state of the art technologies. We are committed to providing an outstanding training environment and research experiences that will enhance your career. The education, expertise, initiative and dedication of the postdoctoral associates engaged in these projects will be important to the success of the studies. This is an opportunity to become part of a winning team that is working to discover novel ways to prevent infectious diseases.


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Science Program Officer

Date Posted:
5/14/2017

Kavli Foundation

CA

Position Description:
About the Foundation

The Kavli Foundation is excited to announce their relocation to Los Angeles/Playa Vista area! Both newly created and existing positions and opportunities are available. The Kavli Foundation is dedicated to advancing science for the benefit of humanity, promoting public understanding of scientific research, and supporting scientists and their work.

The Foundation supports a community of excellence in neuroscience, nanoscience, astrophysics, and theoretical physics through prodigious Kavli Institutes, groundbreaking meetings and initiatives, prestigious million-dollar Kavli Prizes and supporting science communications and public engagement.

About the Job
The Kavli Foundation seeks a Science Program Officer. Reporting to the Executive Vice President of Science Programs, the Science Program Officer will partner with the President of the Foundation and Executive Vice President of Science Programs in monitoring, developing, and implementing the Foundation's scientific programs. These programs include the Kavli Institutes in Science, the Kavli Frontiers of Science (a joint program with the U.S. National Academy of Sciences), Kavli Futures Symposia, Kavli Foundation programs with scientific societies, and other science-related activities of the Foundation. The successful candidate should bring to the position: scientific expertise in the life sciences as well as interest in the Foundation's other sciences, the ability to gather and analyze information relevant to the Foundation's science programs, the ability to evaluate programmatic processes and challenges, the ability to develop and implement newly designed programs and to monitor programs in a timely manner. The Science Program Officer will be an integral part of a small staff that operates its programs.

Duties and Responsibilities:

Planning strategic future directions for Science Programs
Working closely with the Executive Vice President of Science Programs, the successful candidate will develop future scientific programmatic directions.

Interacting, monitoring and evaluating selected Kavli Science Programs
The Science Program Officer will interact frequently with scientists from the Kavli Institutes and other Kavli scientific programs, and will periodically make visits to the science program sites. Such visits are to evaluate the particular program's scientific accomplishments, identify any current issues, and learn of plans for the future. The Science Program Officer will conduct intensive data gathering, prepare write-ups about programs of the Foundation and be responsible for project coordination within science programs.

Gathering and analyzing information needed to evaluate current Kavli Institute programs
To accurately understand the success of the Kavli Institutes, the Foundation needs to gather and analyze information about the range of institute organizations, members, and on-going programs.

Activities of the Science Program Officer will include:

  • surveying relevant literature using scientific knowledge
  • conducting interviews with many members of the Institute to understand its programs in detail
  • participating in conferences, conference calls, and other events where relevant information is presented
  • drafting written materials including detailed reports of information gathered

Should the Foundation consider establishing additional Kavli Institutes, the successful candidate will gather and analyze relevant information

Activities of the Science Program Officer will include:

  • identifying a pool of institutions that might become the home of a new Kavli Institute
  • gathering information needed to vet a candidate institution once that institution has become a serious candidate for a Kavli Institute
  • preparing a precise summary of information gathered

Organizing, or helping to organize, scientific conferences

Perform special studies/projects as requested by the President and the Executive Vice President of Science Programs

Qualifications:

  • Ph.D. in Life Sciences with minimum ten years of experience beyond Ph.D. Knowledge in the life sciences will be very helpful. A specialty in neuroscience is highly desirable
  • Experience and understanding of academic organizational structures and decision making processes
  • Familiarity with funding opportunities relating to higher education in science
  • Strong oral and written skills
  • Ability to synthesize and analyze information
  • Intrinsic curiosity about science is vital
  • Conduct surveys to generate data on science programs as needed
  • Ability to work as a member of teams consisting of both internal and external stakeholders
  • Skill at handling multiple tasks
  • Ability to convene, facilitate, and develop trusted relationships among the Foundation's stakeholders
  • Willingness to travel in conjunction with job responsibility; minimum 20% travel.

To Apply:
http://www.kavlifoundation.org/jobs or https://workforcenow.adp.com/jobs/apply/posting.html?client=kavli&ccId=19000101_000001&type=JS&lang=en_US


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Rita Allen Fellowship for Science Communication

Date Posted:
5/14/2017

Rita Allen Foundation

MA

Position Description:
The Rita Allen Foundation and WGBH Boston are pleased to announce the Rita Allen Fellowship for Science Communication. This new program will provide a year's support for one fellow to study the field of science media, experiment with successful media formats and work to expand science literacy in the general public. The fellow will embed at WGBH, one of the pre-eminent science media producers in the US and home to the flagship public media science series NOVA.
The goal of the Rita Allen Fellowship is to identify ways to expand how and to whom science news and information are communicated. It also aims to discover new information by experimenting with best practices that will provide all science media producers with tools to reach new audiences more effectively.
Elizabeth Christopherson, President of the Rita Allen Foundation, says, "The Rita Allen Fellowship for Science Communication will explore the state of science journalism today and propose new and innovative approaches for improving popular understanding of science." She calls science literacy "a cornerstone of our democracy."

About the Fellowship:

The Rita Allen fellow will investigate, first hand, the state of science communication in popular media, examining audiences, approaches and formats. As examples, the fellow might look to answer these questions:

  • What audiences should be targeted in science communication efforts to create greatest short-term and long-term impact?
  • What new content approaches are most effective for engagement and for improving science literacy among specific audience sub-groups or general audiences?
  • Which formats have the best potential for engagement, again thinking of target audiences as well as broad public audiences?

The research will include looking at trends and technologies, and also at how people are finding their own ways to make science media. Details of the fellow's research will be finalized based on the fellow's interest and skills, with the input and collaboration of the Fellowship staff at WGBH.
As the fellow develops and answers the research questions, he/she will also have the opportunity to share this new knowledge with the public. The fellow will report out quarterly on findings to both the Fellowship program and the public via WGBH science media outlets (such as NOVA, the NOVA Next blog, radio programs like PRI's The World, and online and social media platforms), as well as other distribution channels outside of WGBH.
The Fellow will receive a stipend of $82,000 plus benefits, for the year. He/she will live in or move to the Boston area and have office space at WGBH's studios

To Apply:
More information about the Rita Allen Fellowship for Science Communication please contact program coordinator Judith Vecchione.
To apply, click here.

Application Deadline: June 30th 2017


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Staff Scientist Transcranial Magnetic Stimulation

Date Posted:
5/14/2017

NIDA

MD

Position Description:
The National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), is recruiting for a Staff Scientist to conduct Transcranial Magnetic Stimulation (TMS) research within its Intramural Research Program (IRP) located in Baltimore, Maryland. The goal of this search is to identify a candidate who will enhance this collaborative environment between the Office of the Clinical Director (OCD) and the Neuroimaging Research Branch (NRB).

We are seeking a candidate who is committed to scientific excellence, and understands the intellectual benefits of collaborative research to conduct state-of-art research on fundamental mechanisms that underlie drug addiction and to develop strategies for the treatment of the disorder. Applicants must hold an MD, PhD or equivalent degree. Criteria for selection include advanced training in neuroimaging technologies (including TMS, functional MRI, structural MRI, magnetic resonance spectroscopy, EEG etc.) and substantial experience in conducting research on neuroimaging of drug addiction and treatment in both treatment seeking and active drug users. A proven track record of scientific excellence based on postdoctoral experience and publications is required.

The selected candidate will carry out the research within the Neuroimaging Research Branch in collaboration with the Office of the Clinical Director (OCD), and will be responsible for setting up research protocols, conducting experiments on human participants, assisting with the supervision of new trainees (post-doctoral, pre-doctoral and post-bachelor fellows), as well as collaborating with other intramural and extramural research groups. Salary will be commensurate with experience.

To Apply:
The position is open to both U.S. and non-U.S. citizens. Interested candidates must submit a curriculum vita, bibliography, a one-page summary of research interests, and the names and contact information (work/email addresses, phone) of three references (via pdf or Microsoft word format only - paper applications will not be accepted) to: Dr. Elliot Stein, Senior Investigator, atestein@nih.gov

Review of applications will begin in early- to mid-June, and continue until the position is filled


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Program Manager, Graduate School Biomedical Sciences

Date Posted:
5/14/2017

Sanford Burnham Institute

CA

Position Description:
An exciting opportunity is available for a Program Manager to join the Graduate School of Biomedical Sciences at Sanford Burnham Prebys Medical Discovery Institute to help foster the next generation of outstanding biomedical scientists. This new position is a unique opportunity to conceive and develop new programs that will sustain the Institute's education and training legacy and contribute to the success and reputation of the Graduate School of Biomedical Sciences.
With a current steady state of 30 Ph.D. students, the Program Manager will be an integral member of the Graduate School team. The Program Manager will serve in a key role to establish our approach to ensure future sustainability, create an outreach strategy to support long-term goals and develop resources to support the recruitment and retention of current and future graduate school students. This position will report to the Director of the Office of Education, Training and International Services and work closely with the Dean of the Graduate School.

Duties & Responsibilities:
Student Retention and Program Sustainability

  • Identifies funding opportunities and authors grant applications and technical reports to foundations and other funding sources to support programs and program activities, including outreach and pipeline programs
  • Develops and maintains funding resource database with fellowship/funding opportunities for graduate students
  • Identifies and communicates opportunities to both faculty and students
  • Builds and maintains relationships with local biotech/pharma companies and identifies potential internship opportunities for grad students
  • Leads collaborative partnerships with the Philanthropy department and provides program information as needed to support fundraising efforts towards program sustainability

Recruitment

  • Develops and implements recruiting strategy:
  1. Identifies and attends appropriate recruiting fairs/activities
  2. Manages prospective student prospect lists
  3. Maintains communication and builds relationships with prospective students
  4. Supports student recruitment, new student selection process, and onboarding of new students

Communication and Outreach

  • Develops and manages outreach programs to support goals:
  1. Cultivates pipeline programs including summer science programs and grant-funded pipeline programs, with a focus on underrepresented minority populations
  2. Establishes alumni engagement strategy and identifies opportunities to provide alumni with educational and career development resources
  3. Identifies additional opportunities for engaging populations that align with GSBS strategy
  • Leads collaborative partnerships with the Communications department and provides graduate student and graduate program information as needed to support development of outreach/recruiting materials
  • Develops content for and maintains the internal and external GSBS webpages to meet established goals related to alumni, recruitment, sustainability, and accreditation
  • Manages social media presence to meet established goals related to alumni, recruitment, and sustainability
  • Maintains alumni database of SBP graduate students
  • Participates in OETIS programs and events as assigned

Ideal Candidate:
The ideal candidate will bring a strategic approach to developing programs and contribute novel ideas to lay the groundwork in developing a multi-year approach. As a self-starter, this individual will have strong project management skills, able to see both the big picture and understand the details and will have demonstrated ability of overcoming obstacles to achieve results.
We seek an individual who is a strong collaborator and communicator who is comfortable promoting the benefits of graduate education to students, faculty and other internal and external partners. Our ideal candidate will be a strong writer, and preference will be given to those that have experience developing marketing or recruitment materials and strategies as well as those who have experience managing the social media presence of a program or department. The preferred candidate will have experience communicating the importance of science and the value of STEM education and educational programs to both scientific and non-scientific audiences.
Individuals who understand the unique issues faced by underrepresented minority and international populations are highly desired. An individual with knowledge of how biomedical research education programs are funded would also be preferred.

Required Experience:

  • Bachelor's degree in the biomedical sciences, education, or another relevant discipline required; Master's degree preferred
  • Minimum three years of experience working in higher education; A PhD in a STEM discipline may be accepted in lieu of experience
  • Experience working with and developing programs for high school and/or undergraduate students
  • Experience writing grants and/or funding proposals
  • Experience working with various levels of higher education departments/programs, including deans, faculty, administration, students
  • Experience working with biomedical/STEM-related programs, specifically for pipeline development towards PhD attainment, is preferred

To Apply:
For more information and to apply online please visit https://www.sbpdiscovery.org/about/careers?jobID=219254 and include a cover letter with your resume.


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Program Director

Date Posted:
5/14/2017

Pacific Northwest Research Institute

WA

Position Description:
The Pacific Northwest Research Institute (PNRI) has identified a promising technology for treating fungal infections and is actively pursuing funding to advance its development towards commercialization through a grant from the Congressionally Directed Medical Research Programs (CDMRP). The successful candidate will develop a pre-proposal, and, if invited, a full research project proposal on a contract basis. If the project is subsequently funded, the candidate will transition to become the Program Director, leading and managing the project to success.

The initial award for the project is for four (4) years. It is anticipated that the Program Director will establish a virtual project team, achieving project goals by establishing relationships with academic, independent research institute, and for-profit collaborators. PNRI will sponsor the project and provide the administrative infrastructure.

Qualifications:

  • Advanced degree in a life sciences discipline required.
  • Experience managing large-scale, milestone-driven research projects required.
  • Demonstrated success in identifying and establishing collaborative partnerships required.
  • Demonstrated knowledge of preclinical drug development requirements required.
  • Experience in antifungal drug development, including in vitro and in vivo experimental design and execution for a variety of indications and routes of administration, required.
  • Understanding of U.S. FDA and global regulatory requirements relevant to the development and approval of antifungal therapeutics required.
  • Working knowledge of current antifungal agent research and development programs preferred.
  • Experience as a DoD performer or familiarity with Department of Defense (DoD) performance requirements preferred.
  • Experience writing proposals for DoD funding preferred.

Traits and Skills:

  • Demonstrated ability to think and plan strategically.
  • Excellent project and personnel management skills.
  • Excellent interpersonal, communication and networking skills, along with an ability to interact with scientific researchers.
  • Excellent problem solving and conflict resolution capabilities.
  • Excellent oral, written and presentation skills.
  • High energy, enthusiastic, and goal driven.

About PNRI:
The Pacific Northwest Research Institute (PNRI) is an independent, nonprofit, biomedical research institute committed to the discovery and development of scientific advances to improve the health of all people. PNRI seeks a dynamic professional with experience designing and managing development programs for antifungal therapeutics for the position of Program Director, Antifungal Therapeutics

To Apply:
For immediate consideration, candidates should submit the following to hr@pnri.org.

  1. A cover letter that addresses the criteria outlined under Qualifications and Experience;
  2. A curriculum vitae (listing only published or accepted papers);
  3. A list (including email addresses) of three (or more) professional references.

Applicants should be prepared to prove eligibility to be employed in this position in accordance with all applicable laws. Review of applications will continue until a suitable candidate is identified.


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Assistant Professor Biological Sciences

Date Posted:
5/14/2017

Bronx Community College

NY

Position Description:
The Department of Biological Sciences at Bronx Community College invites applications for two tenure-track positions at the rank of Assistant Professor to begin in August 2017.

Bronx Community College is among the nation's top ten colleges in minority enrollment. Our student body reflects the diversity of the Bronx; we serve approximately 11,000 students from 100 countries. We are a diverse faculty that values pedagogical inquiry and dedication to teaching. The Biological Sciences Department currently offers a Liberal Arts Degree with a concentration in Biology, as well as programs in Biotechnology, Medical Laboratory Technology, Horticulture and Animal Care and Management.

Candidates should have a genuine passion for teaching and scholarship in their fields and should be able and willing to work cooperatively with others for the benefit of the department and college.

Teaching responsibilities include teaching courses in General Biology, Human Anatomy and Physiology, Microbiology and other specialized courses as well as student academic advisement and mentoring. Evening or weekend teaching may be required.

Qualifications

  • Ph.D. degree in area(s) of experience or equivalent.
  • Strong preference will be given to candidates who have previous college teaching experience, a strong record of scholarship and experience working collaboratively and cooperatively with others for the benefit of the institution.
  • Teaching experience with culturally and linguistically diverse student populations at the undergraduate level is strongly desired, as is experience with flipped classrooms, pedagogical inquiry, and conducting research with students.

CUNY offers faculty a competitive compensation and benefits package covering health insurance, pension and retirement benefits, paid parental leave, and savings programs. We also provide mentoring and support for research, scholarship, and publication as part of our commitment to ongoing faculty professional development.

To Apply:
Applicants must apply online by accessing the CUNY website at www.cuny.edu and navigating to the following links: Select "Employment", then select "Search Job Postings" and find JOB ID #16728. Please attach resume and cover letter. References on request. Please do not include any other documentation.

For general assistance with your CUNYfirst application, please go tohttp://www.cuny.edu/employment/jobsysteminstructions.html for information.


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Assistant Science Editor

Date Posted:
5/11/2017

Journal Clinical Investigations

MD

Position: Assistant Science Editor for the Journal of Clinical Investigation Location: Johns Hopkins University East Baltimore campus Reports to: Executive Editor and Editor-in-Chief Description: The Assistant Science Editor will provide operational oversight for the Journal of Clinical Investigation’s Johns Hopkins University editorial office. The Assistant Science Editor will schedule and staff editorial board meetings and Associate Editor calls. The Assistant Science Editor will also be responsible for editing titles and abstracts to conform to journal style. Additionally, this position will work closely with the Editorial Board to identify and solicit authors for the Commentary feature and be responsible for associated editing. Other editorial duties may be added as the Assistant Science Editor gains experience in the position. Scope of the work: • Acts on behalf of the Editorial Board in correspondence with authors, reviewers, and outside parties • Manages operations of the peer review process for the Journal of Clinical Investigation • Attends weekly Editorial Board meetings on Johns Hopkins University’s campus • Has subject matter expertise to assist with editing of manuscripts and other features. • Responsible for the timely turnover of abstract revisions to the production team • Responds to scientific queries from copy editors and production editors • Solicits and edits Commentary article assignments and other features as needed. • Performs all duties under strict time-sensitive deadlines, as they relate to journal production schedule and journal performance metrics Qualifications: The candidate must have completed a Ph.D. in the biological sciences. The ability to manage multiple deadline-oriented tasks and excellent communication skills are essential. Previous editorial experience is not required; however, candidates with experience are also encouraged to apply. About the Journal: The Journal of Clinical Investigation is a publication of the American Society for Clinical Investigation. Founded in 1924, the Journal of Clinical Investigation is a premier venue for discoveries in basic and clinical biomedical science that will advance the practice of medicine. Applying for the position: Applications will be considered on an ongoing basis through July 1, 2017. Interested candidates should submit a cover letter, CV, and a list of three references to Executive Editor Sarah Jackson at editors@the-jci.org.


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Genomics Application Specialist

Date Posted:
5/7/2017

Qiagen

INT

Covers commercial aspects of the pre and post-sales support process for QIAGEN’s Genomics solutions portfolio (QIAGEN NGS-GeneReader System, universal NGS solutions and related Bioinformatic solutions)
- Is responsible for complete workflow selling, product demonstrations, application consulting, workshops, training and on-site support,
- Supports customer throughout product lifecycle and provide customer product training as needed
- Maintains and develop positive relationships with customers and references, Assist in the development and maintenance of reference customers
- Meets/Exceeds sales targets
- Increasing sales by actively selling to end users, maximizing consumable pull-through
- Plans, forecasts and achieves objectives, key performance indicators and revenue forecasts for their business



- Bachelor of Science, PhD or equivalent experience
- 3+ years NGS lab experience or NGS technical support experience
- Proven work experience in sale and developing  customer relationships
- Proven track record (OTE) or laboratory experience
- Language: Italian/French



- Knowledge of relevant markets
- Excellent communication skills at all business levels
- Willingness to travel (60% -80%)
- Willingness and ability to take on additional responsibilities and undertake challenging tasks and/or projects

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NGS Scientist

Date Posted:
5/7/2017

Qiagen

MA



The NGS Scientist will be responsible for development of novel, streamlined methods of nucleic acid processing and amplification compatible with Qiagen’s NGS workflows. This position will work closely with library preparation and sequencing disciplines. The positon will have an important role in bringing innovative solutions to current and future NGS platforms and expanding the range of applications served by these platforms.
The NGS Scientist will:
- Investigate and develop technologies and approaches to DNA libraries clonal amplification processes which significantly improve performance and capabilities of the NGS workflow.
- Work closely with the sequencing team (sequencing chemistry, flow cell, sequencer) to migrate these improvements into the workflow and contribute to project goals.
- Document experiments in compliance with QIAGEN global product development process for molecular diagnostics business area.



- 5+ years of work -related experience in that field.
- MA or MS degree within the applicable field with a minimum of 2+ years of work-related experience also qualifies for this position.
- PhD with no additional experience may qualify for this position.
Skills required:
- Experience with nucleic acid amplification and detection technologies.
- Experience with product development under design control is preferred.
- Excellent understanding of the underlying technical principles of next generation sequencing chemistries and workflows, associated instrumentation platforms and data analysis.
- Mandatory experience in next generation sequencing (NGS) technology development (DNA amplification, sample preparation, chemistry, instrumentation).
- Strong technical writing and presentation skills, prepare data for presentation and present data in lab meetings and to internal collaborators.



- Working Environment Mechanical hazards, chemical hazards, biological hazards.
- Physical Requirements Sit, move, speak, hearing acuity.
- Lifting Requirements Sedentary work (exerting up to 10 pounds of force).

We are an Equal Opportunity Employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity, status as a veteran, and basis of disability or any other federal, state or local protected class.


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Scientist I

Date Posted:
5/7/2017

Illumnia

CA

Do you want to make a difference? Illumina’s mission is to improve human health by unlocking the power of the genome. If that inspires you, let’s talk. We’ve built a culture fueled by innovation, collaboration and openness, and established ourselves as the global leader in DNA sequencing and array-based technologies. Our people and our technology change lives by driving advancements in life sciences, oncology, reproductive health, agriculture and other emerging markets. We are deeply passionate about what we do, because we know that our work has the power to improve lives.

We’re an established company with a track record of phenomenal growth. Our revenue grew from $10 million in 2002 to approximately $2.4 billion in 2016. Our growth isn’t just revenue, we’ve been hiring the best and the brightest. Perhaps that’s why MIT has ranked Illumina near the top of its “World’s Smartest Companies” list each of the last three years. If you thrive in a brilliant, fast-paced, and mission-driven environment, Illumina is the place for you – imagine the possibilities.

Position Summary:

We are looking for a scientist with experience in Chemistry to contribute to a team within Consumables Development. Experience could be industrial or academic and could include oligonucleotide synthesis/modification, fluorescence, particle/bead modification, surface modification, biomaterials, (bio)conjugation chemistry, and/or the analytical techniques associated with these areas. We are particularly interested in candidates that bring a strong fundamental skill set to the table while having shown success working at the interface of chemistry and biology or chemistry and materials.
As a successful candidate you will work in a dynamic, team-oriented environment to create genomic analysis devices that enable leading-edge medical research.  You will be a key contributor within integrated and multidisciplinary teams developing new, and improving existing nucleic acid sequencing and sample preparation technology platforms.

Responsibilities:

  • Develop new and existing reactions at the chemistry, biochemistry and materials interface for Illumina’s sequencing and sample preparation platforms.
  • Explore new reaction methodologies to expand the Illumina portfolio of sequencing and sample prep chemical transformations and isolation techniques.
  • Perform in-depth analyses using techniques such as fluorescence spectroscopy, ellipsometry, FTIR, HPLC, NMR, GPC, SEC, QCM, and other techniques at the chemistry/materials interface.
  • Modify surfaces and/or particles toward making functional materials at the biochemistry, chemistry, and/or physics interface.
  • Perform and lead failure analysis.
  • Teach methods developed to other scientists, engineers, research associates, of a range of experience and education levels.
  • Work collaboratively with chemists, biochemists and bioinformaticians, developing new components for DNA analysis platforms. 
  • Present clear and concise written and oral communications to colleagues and supervisors, lead and/or participate in technical meetings, and provide recommendations based on technical results.

All listed tasks and responsibilities are deemed as essential functions to this position; however, business conditions may require reasonable accommodations for additional task and responsibilities.

Preferred Educational Background:

The ideal candidate will have a PhD in Chemistry or a related field. Postdoctoral research is preferred.

Preferred Experiential Background:

Competitive candidates will have 0-3 years of industrial experience. In addition, candidates will have performed many (but not necessarily all) of the following:
 

  • Demonstrated experience solving challenging, interdisciplinary problems at the interface of biology, chemistry and materials science
  • Used fluorescence-based methods for protein or material labeling techniques such as characterization of surface functionalization and molecular interactions.
  • Developed polymer chemistry or organic chemistry reactions in the context of materials or nanotechnology. This could include methods for bioconjugation and cross functionalization of materials.
  • Demonstrated ability to overcome technical challenges in a fast-paced environment within an interdisciplinary team setting

 


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Research Scientist

Date Posted:
5/7/2017

Illumina

INT

This is a unique opportunity to join a talented team of scientists and engineers at the cutting edge of next-generation sequencing (NGS). As a Research Scientist in the Research and Technology Development Department at Illumina you will work in a dynamic, team-oriented environment and help create novel molecular biology tools for the preparation of libraries for sequencing on Illumina platforms. You will collaborate with internal partners to develop new workflows and translate them to new hardware. This position will require working as a part of multidisciplinary team developing state-of-the-art technology.
 
Job duties include but are not limited to:
 

  • Developing and optimizing new reagents and methods for NGS library preparation and sequencing
  • Collaborating with scientists and engineers in translating these workflows to new instruments and consumables
  • Diagnosing and finding innovative solutions to difficult problems
  • Streamlining complex protocols
  • Performing NGS runs on Illumina sequencers when needed
  • Analyzing complex data sets and interpreting the results of your own and teammates experiments
  • Preparing reports, presenting results, and communicating effectively with senior management and colleagues

 
Education:
 

  • A PhD in the biological sciences is required

 
Experience:
 

  • Experience in NGS library preparation and/or sequencing is required
  • Experience with developing reagents for point-of-care or cartridge-based diagnostics would be useful
  • Demonstrated competence in troubleshooting and overcoming challenges
  • Good written and verbal communication skills
  • Standard computer skills including proficiency in PowerPoint and Excel

 
This is a highly talented and focused R&D team, working at the forefront of NGS technology. We rely on scientists who thrive in a multidisciplinary environment, who bring new expertise and skills, and are happy to broaden and develop their research interests.
 
Interested parties will need to apply via our careers website and use the reference 5810BR to apply:
 
http://www.illumina.com/company/careers/search-jobs.html
 
 
 
All About Us
 
Headquartered in San Diego, California, Illumina (NASDAQ: ILMN), is a leading developer, manufacturer, and marketer of next generation life science tools and integrated systems for large-scale analysis of genetic variation and biological function. These systems are enabling studies that were not even imaginable just a few years ago, and moving us closer to the realization of personalized medicine. With the innovative advances in our sequencing technologies, we are rapidly impacting the clinical market in areas such as reproductive health and oncology. The expanding Illumina oncology portfolio of next- generation sequencing NGS and microarray technologies is revolutionizing cancer genomics research. Our customers include a broad range of academic, government, pharmaceutical, biotechnology, and other leading institutions around the globe.
 
lllumina has experienced phenomenal growth from $10 million in revenues in 2002 to over $1.9 billion in 2014. Forbes named Illumina #1 on the 2009 list of 25 Fastest-Growing Technology Companies in the United States, the second time over a three year period that Forbes ranked Illumina #1 on its list of rapidly growing technology companies. Illumina was also named #1 smartest company in the world as part of MIT’s 2014 Technology Review.  As of December 2014, the company had a $26 billion market capitalization.
 
 
 


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Senior Staff Scientist

Date Posted:
5/7/2017

Bio-Rad

CA

What you'll be doing:

 

  • The successful candidate is expected to conduct independent investigation, with minimal supervision, in the areas of chromatography media characterization and their applications in biomolecule separation.
  • Demonstrated experience and expertise in polymer particle analysis, protein analysis and activity assay is desired.
  • He or she will design and run experiments, supervise junior team members, and communicate findings to colleagues and management.
  • This position requires the ability to work both independently and as a team.
  • Attention to detail when developing and executing an experiment is essential.
  • The successful candidate will be able to record, analyze and present data in an efficient and clear manner.

 

What you'll need for this role:

 

  • The ideal candidate will have BS degree with 10+ years, a master’s degree with 5+ years, or a Ph.D. degree with 2+ years of industry or core lab experience, in chemistry or chemical engineering or related field.
  • Experience in polymer particle/polymeric material characterization
  • Experience in protein purification from mammalian cell culture harvest/bacterial lysate culture using a variety of chromatography and membrane filtration techniques
  • Experience in packing large chromatography columns for protein manufacturing a plus
  • Experience in using Design of Experience (DoE) for experimental design and execution a plus
  • Experience in protein modification/conjugation reactions and product characterization, protein conformation/function analysis, and experience with a variety of protein activity assays a plus

 

What’s in it for you:

 

  • Competitive pay and great benefits including medical, dental, vision, 401k and more
  • Opportunities for growth and training
  • Stability of a profitable 60+ year old company
  • Great work environment

 

About Bio-Rad:

 

Bio-Rad is a global leader providing a broad array of clinical diagnostics and life science research products. With a team of more than 7,800 employees and a global network of operations serving our customers, we help people live longer, healthier lives.

 

Bio-Rad was founded over six decades ago and has continued to provide the healthcare industry with innovative and useful products that help life science researchers accelerate the discovery process and medical diagnostic labs obtain faster, better results.


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Field Application Scientist

Date Posted:
5/7/2017

Bio-Rad

MA

 

What you'll be doing:

 

The HuCAL Application Specialist provides technical consultancy to sales representatives and customers to enhance customer satisfaction and drive HuCAL sales of custom monoclonal antibody related products, services and licenses and Antibody Library transactions. This routinely includes scientific project discussions and presentations, project design, liaising with in-house generation/production/R&D scientists, supporting contract negotiations and supporting pricing negotiations of service agreements in order to strengthen the market position of Bio-Rad. Executes customer training where applicable.
 
85%
Collaborate with the sales organization on the acquisition of new customers in the pharmaceutical, diagnostics and research markets by following up on leads/ inquiries that come in through the sales organization; preparation of customer project descriptions and financial quotations for submission to customer while involving the sales organization in all steps of the customer facing processes.
Facilitation/organization of scientific discussions between customers and generation/production Scientists while involving the sales organization in all steps of the customer facing processes.
Execution of all required internal process for quotations, order management and invoicing.
Maintaining and developing existing Customer contracts including maintenance of Customer contact data; project management including order and invoice processing and post-delivery customer support while involving the sales organization in all steps of the customer facing processes.
Participation in negotiation of service and license agreements with input of Field Sales Managers/ Legal/IP.
Conducting customer visits, sales campaigns and road shows together with/without field sales organization members, attending exhibitions and shows, including making HuCAL Scientific and Sales presentations.
Handles field support for large sales accounts or contracts.
Handles large, complex problems and accounts.
Provides feedback to Sales Management/Marketing regarding services/products requested by customers.
Decides on best training program for customers where applicable.
Has ability to decide and organize training programs for sales reps with advice from Regional Sales manager and Supervisor.
Provides troubleshooting when needed.
 
15%
Contribute to sales forecasting as that is migrated to the account managers. Provision of  sales forecasting and other relevant sales information in addition to details of market developments, customer needs and success factors as well as ideas and suggestions for new product and service offerings to Supervisor/Marketing/Management as appropriate and as requested.
The location will be Boston or New Jersey
Required Skills: 
Independent project management skills, good organizational skills, effective time management skills, excellent written and  oral communication skills , detail & results orientation, determination, self-motivation, flexibility, enthusiasm,  good presentation skills, technical background in molecular biology immunology or a related field. 
Independent project management skills, good organizational skills, effective time management skills, excellent written and accuracy, high degree of numeracy, and results orientation. Sales analysis, forecasting and budgeting skills are required.
Effective problem solving skills & high level of numeracy. Understanding of basic immunological methods, including ELISA, FACS analysis and other antibody involving methodologies.
 
 
What you need for this role:
 
  • Advanced degree minimum, PhD in life sciences preferred, including experience in one or more of the following areas:  genetic engineering (phage display), biochemistry, molecular biology, microbiology and/ or immunology.
  • 5+ years related experience, or equivalent combination of education and experience.
  • Minimum 3 years life science laboratory experience, ideally with molecular biology, genetic engineering and/or immunology.
  • Office based position. 
  • Domestic and international travel of up to 50% possible.
  • Microsoft Outlook Excel, Word and PowerPoint, Salesforce.com, laptop, telephone and mobile phone.
  • Driver’s License with clean driving record.
  • Can be based in Boston or New Jersey area

 

What’s in it for you:

 

  • Competitive pay and great benefits including medical, dental, vision, 401k and more
  • Opportunities for growth and training
  • Stability of a profitable 60+ year old company
  • Great work environment

 

About Bio-Rad:

 

Bio-Rad is a global leader providing a broad array of clinical diagnostics and life science research products. With a team of more than 7,800  employees and a global network of operations serving our customers, we help people live longer, healthier lives.

 

Bio-Rad was founded over six decades ago and has continued to provide the healthcare industry with innovative and useful products that help life science researchers accelerate the discovery process and medical diagnostic labs obtain faster, better results.

 

EEO/AA Employer/Veterans/Disabled/Race/Ethnicity/Gender/Age

 

To all recruitment agencies: Bio-Rad does not accept agency resumes, unless the agency has been authorized by a Bio-Rad Staffing Representative. Please do not submit resumes unless authorized to do so. Bio-Rad will not pay for any fees related to unsolicited resumes.

 


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Tech Editor

Date Posted:
5/7/2017

Bio-Rad

CA

What you’ll be doing:

 

  • Serve as editor and writer for the Life Science Group's Global Marketing and Communications Department
  • Partner with Marketing, Campaign, and Product Managers to develop concepts and content for advertising and marketing campaigns
  • Develop, write, and edit content marketing articles such as trends articles, customer stories, and content for bioradiations.com
  • Develop, write, and edit marketing materials such as brochures, fliers, technical/application notes, posters, video scripts
  • Ensure marketing and advertising collateral meet editorial style guidelines and are scientifically accurate
  • Collaborate in project teams with Art Directors, Graphic Designers, and Project Managers

  

What you need for this role:

 

  • Master's degree in the life sciences (a must) and at least 3 years of experience writing and/or editing for a scientific audience or a PhD in the life sciences
  • Scientific knowledge -- Understands basic scientific concepts and laboratory techniques in molecular biology and biochemistry (chromatography, western blotting, etc.); communicates using accurate scientific language; understands what motivates researchers in the life sciences and how to write copy that resonates with them
  • Scientific writing/editing -- Is familiar with the structure and style of scientific articles; has written or contributed significantly to the writing of scientific articles; can provide feedback on logical progression of scientific ideas/arguements
  • Writing Skills -- Has strong writing skills and the ability to write a variety of materials (technical/application notes, advertising copy, brochure/flier copy, customer stories and trends articles, video scripts); must be able to adapt voice to match intent/purpose of each piece
  • Editorial Skills -- Has strong attention to detail and is familiar with Chicago Manual of Style or AMA Manual; is able to ensure internal consistency when editing lengthy documents; is able to consistently enforce style guidelines across all documents
  • Organizational Skills -- Is able to manage multiple projects simultaneously and effectively under tight deadlines
  • Must be able to uphold editorial style guidelines and provide guidance on writing style and strategy in a professional manner
  • Enjoys and is able to work effectively in a changing team environment
  • Candidates will be asked to take a writing and editing test for this position

 

What’s in it for you:

 

  • Competitive pay and great benefits including medical, dental, vision, 401k and more
  • Opportunities for growth and training
  • Stability of a profitable 60+ year old company
  • Great work environment

 

About Bio-Rad:

 

Bio-Rad is a global leader providing a broad array of clinical diagnostics and life science research products. With a team of more than 7,800  employees and a global network of operations serving our customers, we help people live longer, healthier lives.

 

Bio-Rad was founded over six decades ago and has continued to provide the healthcare industry with innovative and useful products that help life science researchers accelerate the discovery process and medical diagnostic labs obtain faster, better results.


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Science Editor - Biology (Part-time)

Date Posted:
5/7/2017

American Institutes for Research

DC

Overview:

The American Institutes for Research (AIR) is a leading research organization specializing in all aspects of education and other social policy issues as well as workforce research and analysis. Our programs aim to improve the quality of education and the workplace for all people by evaluating the effectiveness of education initiatives, conducting basic education and workforce research, and furnishing technical assistance and training at national, state, and local levels.

AIR is currently seeking a Part-Time Science Editor- Biology for our Washington, D.C. office.
 

Responsibilities:

The biology editor will lead the development of test questions from authoring to operational usage. The editor is responsible for ensuring the items are technically accurate, stylistically appropriate, and aligned to test specifications.
 

Qualifications:

• PhD in Biology (Anatomy & Physiology/Cell Biology/Neuroscience) and teaching experience of undergraduate biology is required.
• Excellent written communication skills and ability to collaborate in a team environment
• Significant knowledge of multiple fields within biology at the undergraduate level is preferred.
• Test development experience is preferred.

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Scientific Editor

Date Posted:
5/7/2017

Spandidos

INT

Spandidos Publications was founded in 1992 and has developed into a leading publishing group in the biomedical sciences field. Spandidos Publications is the 3rd largest publisher in the world in the field of oncology and 5th in the field of medicine research and experimental based on the Web of Science ISI ranking. We currently publish eight journals: International Journal of Molecular Medicine, International Journal of Oncology, Molecular Medicine Reports, Oncology Reports, Experimental and Therapeutic Medicine, Oncology Letters, Biomedical Reports and Molecular and Clinical Oncology. All journals published by Spandidos Publications maintain the highest standards of quality and the members of their Editorial Boards are world-renowned scientists. The company currently employs more than 100 employees and has offices based in Athens and London and receives high quality submissions from authors worldwide, including Europe, the Americas, Asia and Africa. Do you have a passion for the English language and the ability to comprehend new scientific concepts and ideas? Spandidos Publications are currently searching for a Scientific Editor to join their expanding London-based team. The role will consist of copy-editing technical manuscripts to a high standard and in a timely fashion, in order to obtain clarity and maintain consistency with the in-house journal style. Candidates will be required to oversee the journal production process, including the set-up, proofreading and administration of articles, and also liaise with authors, academic editors and all members of the production team. Therefore, strong interpersonal skills and the flexibility to adapt to any task are a necessity.


Candidates must have a degree in the biological sciences and possess a high level of written English. The position requires meticulous attention to detail and strong computer skills, with knowledge of Mac OS preferred. Although prior scientific copy-editing experience is preferred, this is not essential, as training will be provided to any suitable candidate.

This is a full-time position with a friendly and established company that publishes high-quality scientific articles both online and in print. Benefits include a competitive starting salary, with scope for increase based on performance, and the opportunity for further career advancement.

Please send your CV and a cover letter, stating salary expectations and quoting the job reference (SP/SCE1/SP) by e-mail to: jobs@spandidos-publications.com

Spandidos Publications offers a competitive salary and benefits package including 25 days holiday plus bank holidays, 35 hour working week, contributory pension scheme, private health insurance, dental cover, optical cover, discounted gym membership, cycle to work scheme, weekly fresh fruits, an employee support programme and season ticket loan depending on conditions. 

Spandidos Publications is an Equal Opportunities Employer. We welcome all applications irrespective of race, gender, age, religion or belief, relationship status, pregnancy/maternity, sexual orientation or disability.


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Sr. Technology Licensing Associate

Date Posted:
5/7/2017

JHU

MD

General Description

 

Reporting to a Director of Licensing, this person independently manages a portfolio of life science technologies in order to source, negotiate and execute high value, intellectual property licenses.

Essential Job Functions:
  • Provides sell-side and business development activities around intellectual property commercialization.
  • Develops positive relationships with inventors with the intention of identifying attractive JHU technologies for licensing to start up or established companies.
  • In concert with peers, makes decisions around patenting, marketing and licensing of JHU inventions.
  • Engages with investors and companies to determine their needs and identifies applicable JHU technologies for licensing.
  • Negotiates high value intellectual property licenses for optimal deal structure, valuation and compliance.
Scope of Responsibility
  • Works under the direct supervision of a Director of Licensing in evaluation, marketing and agreement negotiation activities. May manage or mentor junior personnel as assigned.
Decision Making
  • Makes recommendations concerning investments in technologies.
Authority
  • May direct the activities of staff or a function. May not commit JHU to agreement terms without supervisor approval.

 

Qualifications

 

An advanced degree in the life sciences, or business required. PhD, or combination of degree in life sciences with an MBA strongly preferred.

Candidate will have licensing experience in a high performing technology transfer office that is typically gained through a minimum of 4 years of licensing and technology transfer experience; and/or a startup or biotechnology company with business development and deal execution experience.

Candidate will have a working knowledge of intellectual property prosecution, technology valuation and license structure. Most importantly, candidate will have a robust deal sheet of exclusive licenses and options of life science technologies.

Required Skills:

  • Must have the ability to understand complex technologies.
  • Must have knowledge and experience in negotiating business contracts, especially in technology licensing.
  • Knowledge and experience in life sciences or physical sciences preferred.
  • Experience in marketing and sales of intellectual property desired.
  • Must have the ability to work independently and as a member of a team.
  • Must demonstrate outstanding work ethic and desire and ability to work in fast-paced high-expectation environment.
  • Must be a self-starter capable of handling a docket of highly technical inventions, managing a complex patent portfolio, and marketing and licensing technology with minimal supervision.

 

 

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Senior Research Scientist

Date Posted:
5/7/2017

Amlan International

IL

Amlan International, the animal health, and nutrition division of Oil-Dri Corporation of America develops and markets disease management solutions for the global livestock market. Our team of veterinarians, research scientists, and technical service experts work with leading integrators, feed mill operators and farmers to provide solutions that reduce the clinical effects of toxicosis. The complex science of enterosorption forms the core of our innovative solutions. Amlan International - Productivity for Life.

 

Position Summary:  

The successful candidate will help develop new products and applications for Animal Health markets and in fields related to the Life Sciences.  This position will be part of a dynamic and creative Life Sciences team engaged in developing natural disease management solutions for promoting gut health in livestock animals and humans. The position is responsible for helping set up a new microbiology laboratory at the Innovation Center. 

Responsibilities:

  • Performs microbiological tests and scientific research in support of new products and applications.
  • Recognizes key issues and develops the approach and design of projects with some input and relatively little supervision.
  • Actively seek new partnerships for both technologies and analytical support; as well as, develop novel methods in support of product claims. 
  • Work spans scientific ideation, experimental design, and implementation to prototype assessment. 
  • Cross-functional collaboration with other scientists, engineers and management professionals on multidisciplinary projects.
  • Creation and maintenance of quality management systems in the microbiology laboratory 
Requirements
  • Minimum of M.S. degree (or Ph.D. preferable) in microbiology, immunology, molecular or cellular biology, or related biological science field.
  • 5+ years of experience in a commercial or governmental microbiology research lab is desired.
  • Direct experience in our target area (e.g., bacteria of commercial or physiological relevance), and extensive hands-on experience in a variety of antimicrobial test methods.
  • Experience in microbial isolation, cultivation, characterization and identification, in vitro susceptibility, bacteriocidal/bacteriostatic assessments, microbial physiology and/or ecology, 16S rRNA qPCR, Western blotting.
  • History of publication in peer-reviewed journals
  • Experience with anaerobic bacteria, microbial communities, metagenomics, high-throughput screenings, mechanisms of antibacterial action or resistance development.
  • Experience in working in GLP laboratory operations and FDA regulations are a plus.
 

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Electron Microscopy Scientist

Date Posted:
5/7/2017

Argonne National Lab

IL

Description:

The Nanoscience and Technology (NST) Division at Argonne National Laboratory hosts the Center for Nanoscale Materials (CNM), a multidisciplinary user facility with expertise in the characterization, fabrication,  synthesis and theory of nanoscale materials, in addition to performing programmatic science activities. NST research ranges from fundamental to use-inspired nanoscience with connections to industry and the Argonne applied science divisions. The division seeks to bring together scientists and engineers from national laboratories, industry, and academia to meet nanoscience and nanotechnology challenges of the present and future. 

We seek a staff scientist with expertise in the electron microscopy of nanoscale materials to join the Electron and X-ray Microscopy Group in the Nanoscience and Technology Division at Argonne.

The staff scientist should possess a background in electron microscopy, and with a strong interest in the use of data science for electron microscopy research.  He or she is expected to develop a world-class research program of his or her own in the area of electron microscopy of nanoscale materials, and is expected to collaborate effectively with other CNM scientists and users of the CNM.  An interest and experience in applying data science techniques to electron microscopy would be an added plus.  The staff scientist is also expected to have a strong commitment towards building up a robust set of users and collaborators for CNM’s electron microscopy facilities.  The position offers considerable research freedom and the ability to develop a long-term scientific research program. 

A Ph.D. in the physical sciences, with research experience in electron microscopy is required. Postdoctoral research experience is desirable.

We offer a competitive salary and an excellent benefits package.  For consideration, please apply via our website at: http://bit.ly/2mYVUZn.


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Postdoc Biomedical Engineer/Engineer

Date Posted:
5/6/2017

CAMRAS Vision

NC

Overview
Camras Vision is a medical device startup company located at First Flight Venture Center in Durham, NC. We received a National Science Foundation (NSF) Small Business Phase II grant and are participating as a host company in the small business postdoctoral fellowship program sponsored by the NSF. We are seeking PhD candidates or recent PhD graduates with a background in biomaterials and/or fluid dynamics.

The Product
Our company is developing a novel implantable medical device to treat glaucoma. The device is constructed from soft synthetic polymers. It contains a resistance mechanism that can be manipulated non-invasively to set and adjust eye pressure and a filter to prevent infection.

Job Description
We are looking for a postdoctoral fellow to explore any of the following areas over a 2-year fellowship.
• Evaluate filter coatings or new materials to prevent biofilm formation and clogging
• Evaluate lubricating coatings or materials to increase hydrophilicity of the resistance
mechanism
• Evaluate risk of wound leaks and the use of coatings or materials to promote tissue integration
The fellow is expected to work closely with the senior scientist and conduct experiments independently.
The applicant must have a strong background in biomaterials, chemistry, and laboratory
testing. Experience in ophthalmology, microfluidics, and in vivo testing would be preferred, but is not required.

Salary per year: $75,000 plus health insurance benefits Find more information at https://nsfsbir.asee.org/
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Job Requirements

 

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Bioinformaticist

Date Posted:
5/6/2017

Q Squared solutions

NC

EA Genomics, a division of Q2 Solutions, is a premier genomic services organization, excelling in implementing technologies and services to accelerate research in complex human diseases and the optimal treatment and diagnosis thereof. The software infrastructure for analysis and processing in support of those services makes use of a combination of open-source and custom-built, specialized application software.

The Bioinformatics Data Services group within EA Genomics is a multidisciplinary group that works alongside bioinformaticists, software engineers, and laboratory professionals to process and deliver next-gen sequencing (NGS) data. In addition to interacting both with clients and groups within our organization regarding bioinformatic analyses, the group monitors general system health and contributes to improvements in our tools and processes.

PURPOSE

Provide technical expertise as part of an operations oriented bioinformatics team to develop and maintain programs that meet internal and external clients’ needs. Develop or commission solutions for client and/or business needs based on requests or direct/indirect indications. Implement project related solutions to the full scope of scientific and/or bioinformatics programming tasks. Gather and coordinate team efforts around a project or client as needed.

RESPONSIBILITIES
* Evaluate computational efficiency of large-scale scientific computing systems, such as those needed for genomic sequencing, identifying scientific system software components in need of improvement or replacement.
* Manage infrastructure (SW updates/HW replacements) to support large-scale scientific computing projects, such as genomic sequencing.
* Assist Sr. Bioinformaticist in the analysis of client projects or conduct analysis of smaller scale projects independently.
* Develop programming documentation including plans and specifications, as appropriate.
* Provide bioinformatics technical expertise in conjunction with internal and external clients, and independently bring project solutions to teams and department.
* Perform and potentially plan the development, implementation and validation of new product technologies and applications.
* May manage budget and resource requirements; understanding budget and quote assumptions.
* May provide training and guidance to new and lower level staff
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Job Requirements


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REQUIRED KNOWLEDGE, SKILLS AND ABILITIES
* Strong foundational knowledge in Linux/UNIX-based systems
* Proficiency in computing languages such as C/C++, Perl, Shell scripting with Bash environment or similar general purpose programming languages
* Familiarity with quantitative tools or languages such as R, SAS, or related analysis software
* Proficiency in SQL is desired
* Good organizational, interpersonal, leadership and communication skills
* Ability to effectively handle multiple tasks and projects
* Strong level of accuracy and attention to detail
* Ability to establish and maintain effective working relationships with coworkers, managers and clients

MINIMUM REQUIRED EDUCATION AND EXPERIENCE



Bachelor's degree or educational equivalent in bioinformatics, statistics, computer science, biology, genetics or related field and 4 years of relevant experience; or Master’s degree or educational equivalent in bioinformatics, statistics, computer science, biology, genetics or related field and 2 years of relevant experience; or equivalent combination of education, training and experience; or PhD or educational equivalent in computer science, bioinformatics, statistics, genetics/molecular biology, or related field; or equivalent combination of education, training and experience.


PHYSICAL REQUIREMENTS
* Extensive use of telephone, computer aided, and face-to-face communication requiring accurate perception of speech and clear articulation and idea formation.
* Extensive use of keyboard requiring repetitive motion of fingers
* Occasional travel
* Regular sitting for extended periods of time.

EEO Minorities/Females/Protected Veterans/Disabled.

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Cell Biology Scientist

Date Posted:
5/6/2017

Precise=Bio

NC

Precise Bio, a US based company, is looking for experienced and a motivated and innovative candidates for the position of Cell Biology Scientist.

Primary Job Function:

- Apply techniques of tissue culture, histology and molecular biology to support the company’s bio-printer development.
- Develop advanced techniques for handling and analysis of cells, tissues, biomaterials and bioreactors.
- Confirm system and product capabilities by applying current testing methods and work to designing new ones.
- Manage and maintain databases, keep laboratory notebooks, analyze data, prepare presentations and write reports.
- Evaluate future perspectives via collecting and summarizing information related to the research projects.
- Contribute to a multidisciplinary team efforts.
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Job Requirements


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Skills & Qualifications:

- Resourceful, hands-on, problem solving individual with initiative and drive to work innovatively around technical obstacles
- Self-starter who can keep up with a fast development pace
- Demonstrated excellent verbal and written communication skills
- Demonstrated ability to work independently and excellent interpersonal skills to work with others
- Demonstrated ability to effectively manage multiple development projects simultaneously
- Demonstrated ability to manage a team of lab technicians
- Flexibility to work on projects involving more than one engineering discipline.

Education:

PhD required in cell/molecular biology or related fields. A postdoctoral training is an advantage.

Experience / Training Required:

- Good knowledge and research experience in cell biology and regenerative medicine
- Experience growing multiple cell types and experimenting with biomaterials. ,Use of bioreactors and/or microfluidic devices is an advantage
- Experience with imaging techniques

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Interdisciplinary Scientist

Date Posted:
5/6/2017

NIST

MD

Job Overview

Summary

About the Agency

 

The NIST Material Measurement Laboratory (MML) serves as the national reference laboratory for measurements in the chemical, biological and material sciences through activities ranging from fundamental and applied research, to the development and dissemination of certified reference materials, critically evaluated data, and other programs and tools to assure the quality of measurement results. MML is also responsible for coordinating the NIST-wide Standard Reference Material and Standard Reference Data programs.

The NIST Material Measurement Laboratory is seeking a Biologist, Chemist or Physical Scientist to coordinate the MML Safety Program laboratory-wide.

Are you ready to explore your future with NIST?

Your application package may be shared with other selecting officials at NIST with opportunities like the one you are applying to. Additional selections may be made through this vacancy.

Duties

The NIST Materials Measurement Laboratory is seeking a Safety Program Coordinator to assist in leading and managing MML’s safety program. The Safety Program Coordinator is the MML liaison to the NIST Office of Safety, Health, and Environment (OSHE), helps to direct the work of the Division Safety Representatives whose focus is implementation of safety in the Divisions, chairs the MML Safety Council, maintains all MML safety policies and procedures, and keeps MML Leadership informed on the status of safety in MML and on safety at NIST.

At the PB-III level, Incumbent will investigate, analyze and interpret the composition, physical, biological and chemical properties utilized in the laboratories to maintain MML safety policies and procedures to ensure consistency with NIST requirements.

At the PB-IV level, Incumbent will investigate, analyze and interpret the composition, physical, biological and chemical properties utilized in the laboratories to maintain MML safety policies and procedures to ensure consistency with NIST requirements. In addition, at the PB-IV level, the incumbent should maintain a basic knowledge of all NIST Safety programs that apply to MML, work with the MML Director, Deputy Director and Executive Officer to define and implement strategies to accomplish safety objectives, provide leadership in safety program development and implementation, maintain MML Safety policies and procedures and, inform MML Leadership of NIST safety requirements and serve as a resource to MML staff for MML Safety Program Information.

Travel Required

  • Occasional Travel
  • Occasional travel to other Material Measurement Laboratory locations

Relocation Authorized

  • No

Job Requirements

Key Requirements

  • You must be a U.S. citizen
  • You must be registered for Selective Service
  • You must be suitable for Federal Employment
  • Time-in-grade must be met by the closing date of the announcement

Qualifications

For Biologist ZP-0401-III

Basic Requirements:

1. Degree: biological sciences, agriculture, natural resource management, chemistry, or related disciplines appropriate to the position.

OR

2. Combination of education and experience: Courses equivalent to a major, as shown in A above, plus appropriate experience or additional education.

In addition to the above basic requirements, applicants must have 52 weeks of specialized experience equivalent to at least the GS-9 (ZP-II at NIST). Specialized experience is defined as experience applying occupational safety laws, regulations, principles, theories, practices or procedures and advising on occupational safety requirements in a scientific research facility.

OR

3 years of progressively higher level graduate education leading to a Ph.D. degree

OR

Ph.D. or equivalent doctoral degree


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Biological Scientist

Date Posted:
5/6/2017

Airforce

FL

The Air Force's only organization wholly dedicated to leading the discovery, development, and integration of warfighting technologies for our air, space and cyberspace forces.  AFRL traces its roots back to the vision of early airpower leaders who understood science as the key to air supremacy. The passionate commitment of our people to realize this vision has helped create the world's best air, space and cyberspace.

These positions are being filled under the Expedited Hiring Authority for Acquisition Positions and are for anticipated vacancies. 

The positions may be filled at the DR-02, DR-03, or DR-04 level.

The pay band equivalencies are as follows:

DR-02 is equivalent to GS-12 - GS-13

DR-03 is equivalent to GS-14

DR-04 is equivalent to GS-15

 

Basic Pay Range DR-02: $61,289-$96,239
Basic Pay Range DR-03: $84,589-$119,539
Basic Pay Range DR-04: $107,889-$133,444

                                                                                                     

Pay will vary by pay band and geographic location.

This is a public notice and may be used to fill anticipated permanent, temporary or term vacancies with a full-time or part-time work schedule at various locations as vacancies occur during the open period.Modified Term, Term, and Temporary appointments may be extended without further announcement. A modified term appointment may be non-competitively converted to a career appointment.

Your application material will only be reviewed for vacancies received by the closing date of this public notice which match your desired geographic locations, experiences and competencies.  After the closing date you will no longer receive consideration for this public notice.

Duties

MAJOR DUTIES: 0401 - Biological Scientist:  This series covers positions that manage, supervise, lead, or perform professional research, or scientific work in biology, agriculture, or natural resources management.  

Travel Required

  • Not Required

Relocation Authorized

  • No

Job Requirements

Job Requirements

Key Requirements

  • U.S. citizenship required
  • Travel expenses may or may not be paid
  • Recruitment and/or relocation incentives may or may not be used
  • Must obtain/maintain appropriate security clearance required for position
  • A 3-year probationary period is required for permanent positions
  • This is a Public Notice for anticipated vacanies

Qualifications

SPECIALIZED EXPERIENCE:  At least one (1) year of specialized experience at the next lower pay band or equivalent.  Specialized experience must include experience that equipped the applicant with the particular knowledge, skills, and abilities to perform successfully the duties of the position, and that is typically in or related to the work of the position to be filled. To be creditable, specialized experience must have been equivalent to at least the next lower grade level in the normal line of progression for the occupation in the organization and as described in the MAJOR DUTIES section.

To view qualifying education requirements and/or combination of education and specialized experience click on the following link:

http://www.opm.gov/qualifications/Standards/group-stds/gs-prof.asp

AND

Click on the following link to view occupational requirements for this position:

http://www.opm.gov/qualifications/Standards/IORs/gs0400/0401.htm

PART-TIME OR UNPAID EXPERIENCE: Credit will be given for appropriate unpaid and or part-time work.  You must clearly identify the duties and responsibilities in each position held and the total number of hours per week.

ARE YOU USING YOUR EDUCATION TO QUALIFY? You MUST provide transcripts to support your educational claims.  Education must be accredited by an accrediting institution recognized by the U.S. Department of Education. 

FOREIGN EDUCATION SPECIAL INSTRUCTIONS:  Click here

CONDITIONS OF EMPLOYMENT/OTHER SIGNIFICANT FACTS:

  • The employee must meet the Defense Acquisition Workforce Improvement Act (DAWIA) requirements applicable to the duties of the position.
  • Employee is expected to meet Continuing Acquisition Education requirements. 
  • The work may require the employee to occasionally travel away from the normal duty station via military or commercial aircraft.  
  • This may/may not be a Testing Designated Position.  The incumbent may be subject to pre-employment drug testing as a condition of employment, and participateion in random drug testing.
  • Employee may be required to work overtime; other than normal duty hours, which may include evenings, weekends, and/or holidays.
  • The selectee may be required to complete a Confidential Financial Disclosure Report (OGE 450), prior to entering on duty and annually thereafter. 

 A 1-year supervisory probationary period is required, if applicable. All newly-assigned first-level supervisors are required to complete Mandatory Supervisory Training (MST) within 120-days of assignment.


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Health Scientist Policy

Date Posted:
5/6/2017

CDC

GA

The Centers for Disease Control and Prevention (CDC) is the agency Americans trust with their lives. As a global leader in public health, CDC is the nation's premier health promotion, prevention, and preparedness agency. Whether we are protecting the American people from public health threats, researching emerging diseases, or mobilizing public health programs with our domestic and international partners, we rely on our employees to make a real difference in the health and well-being of people here and around the world.

 

 

The January 23, 2017, Presidential Memorandum, entitled "Hiring Freeze," ordered government agencies, including the Centers for Disease Control and Prevention (CDC), to freeze all hiring of Federal civilian employees. In an effort to ensure CDC is best positioned to resume hiring after the hiring freeze expires and the Office of Management and Budget (OMB)/Office of Personnel Management (OPM) issues a joint plan to reduce the size of the Federal Government's workforce, CDC will continue its recruitment efforts (post job vacancy announcements, evaluate and screen applicants, interview, etc.).  This position will not be filled and no job offers will be made until resolution of the hiring freeze, or the position qualifies for a hiring exemption and is approved pursuant to OMB guidance.

Who May Apply: Open to US citizens and applicants eligible under Schedule A authority.

This vacancy is also being announced concurrently with vacancy announcement HHS-CDC-M5-17-1944971under merit promotion procedures. Please review that announcement to see if you are eligible for consideration under merit promotion procedures. Applicants must apply separately for each announcement in order to be considered.

This position is located in the Department of Health and Human Services (DHHS), Centers for Disease Control and Prevention (CDC), National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention (NCHHSTP), Division of HIV/AIDS Prevention (DHAP), Atlanta, GA.

PHS Commissioned Corps Officers interested in performing the duties of this position within the Commissioned Corps (not as a career/career-conditional employee) are encouraged to apply under the merit promotion announcement indicated above.

Additional selections may be made within the same geographical location CDC-wide.

CDC Financial Disclosure —OGE form 450 Holding ourselves to a higher standard; the Centers for Disease Control and Prevention inspires public confidence in its trust responsibilities and mission by maintaining high ethical principles. This position is subject to the confidential financial disclosure requirements of the Ethics in Government Act of 1978 (P.L. 95-521). Therefore, if selected, you will be required to complete a Confidential Financial Disclosure Report (OGE Form 450) to determine if a conflict or an appearance of a conflict exists between your financial interest and your prospective position with the agency. This Information will be required annually.

CDC is an Equal Opportunity Employer

 

Duties

 

As a Health Scientist (Policy) you will:

  • Research, analyze and synthesize evidence to ensure the rigor, transparency, and effectiveness of policy initiatives including the development of evidence-based public health guidelines.
  • Have skills and understanding related to evidence-based processes, critical appraisal methods, systematic reviews, and current methods in policy and guideline development.
  • Plan and manage multiple guideline development-related projects and issues effectively within tight timeframes and allocated resources and ensure they are aligned with current policy, standards, and strategies.
  • Monitor and evaluate the implementation and uptake of policy initiatives including public health guidelines and supporting material.
  • Engage and collaborate with multiple internal and external stakeholders including subject matter experts, grantees, partners, and policy makers.

 

 

Travel Required

  • Occasional Travel
  • Domestic 10%

Relocation Authorized

  • No

Job Requirements

Key Requirements

  • U.S. Citizenship is required.
  • Background investigation required.
  • Transcripts are required.

Qualifications

 

Basic Requirement: Applicants must have successfully completed a full four-year of study at an accredited college or university leading to a bachelor's or higher degree in academic field related to the health sciences or allied sciences appropriate to the work of the position.
In addition to the basic qualifications requirements for GS-13: Applicants must have at least one year of specialized experience at or equivalent to the GS-12 grade level in the Federal service as defined in the next paragraph.
Specialized experience is experience which is directly related to the position which has equipped the applicant with the particular knowledge, skills and abilities (KSAs) to successfully perform the duties of the position, to include experience in the analysis, development, dissemination, or evaluation of public health guidelines, policy issuances, public health research and legislation, or other related material that would impact an organization's public health activities.

 

 

Foreign Education: Education completed in colleges or universities outside the United States may be used to meet the education requirements. You must provide acceptable documentation that the foreign education is comparable to that received in an accredited educational institution in the United States. For more information on how foreign education is evaluated, visit:http://wwwdev.cdc.gov/employment/newhire/foreigned.html.

Conditions of Employment:

1. Security and Background Requirements: If not previously completed, a background security investigation will be required for all appointees. Appointment will be subject to the applicant's successful completion of a background security investigation and favorable adjudication. Failure to successfully meet these requirements may be grounds for appropriate personnel action. In addition, if hired, a background security reinvestigation or supplemental investigation may be required at a later time. Applicants are also advised that all information concerning qualifications is subject to investigation. False representation may be grounds for non-consideration, non-selection and/or appropriate disciplinary action.

2. E-Verify: If you are selected for this position, the documentation that you present for purposes of completing the Department of Homeland Security (DHS) Form I-9 will be verified through the DHS "E-Verify" System. Federal law requires DHS to use the E-Verify System to verify employment eligibility of all new hires, and as a condition of continued employment obligates the new hire to take affirmative steps to resolve any discrepancies identified by the system. The U.S. Department of Health and Human Services is an E-Verify Participant.

3. Direct Deposit: All Federal employees are required to have Federal salary payments made by direct deposit to a financial institution of their choosing.

 

 

4. All qualification requirements must be met by the closing date of the announcement.

5. One-year probationary period may be required.

6. Travel, transportation, and moving expenses will be paid: No

7. Bargaining Unit Position: No

8. Drug Screening Required: No

9. Recruitment Incentive may be authorized: No

10. Annual Leave for non-federal service authorized: No

11. Research position: No

12. Promotion potential: No

13. Supervisory position: No

 

Security Clearance

Public Trust - Background Investigation


Read the full job description

Health Scientist

Date Posted:
5/6/2017

CDC

DC

The January 23, 2017, Presidential Memorandum, entitled "Hiring Freeze," ordered government agencies, including the Centers for Disease Control and Prevention (CDC), to freeze all hiring of Federal civilian employees. In an effort to ensure CDC is best positioned to resume hiring after the hiring freeze expires and the Office of Management and Budget (OMB)/Office of Personnel Management (OPM) issues a joint plan to reduce the size of the Federal Government's workforce, CDC will continue its recruitment efforts (post job vacancy announcements, evaluate and screen applicants, interview, etc.). This position will not be filled and no job offers will be made until resolution of the hiring freeze, or the position qualifies for a hiring exemption and is approved pursuant to OMB guidance.

 

 

The Centers for Disease Control and Prevention (CDC) is the agency Americans trust with their lives. As a global leader in public health, CDC is the nation's premier health promotion, prevention, and preparedness agency. Whether we are protecting the American people from public health threats, researching emerging diseases, or mobilizing public health programs with our domestic and international partners, we rely on our employees to make a real difference in the health and well-being of people here and around the world.

This announcement will be used to fill positions at the Department of Health and Human Services, Centers for Disease Control and Prevention, Center for Global Health.

This vacancy is also being announced concurrently with vacancy announcement HHS-CDC-OD-17-1949138 under competitive procedures. Please review that announcement to see if you are eligible for consideration under competitive procedures.  NOTE: Applicants must apply separately for each announcement in order to be considered.

PHS Commissioned Corps Officers interested in performing the duties of this position with the Commissioned Corps may apply online to this announcement. Candidates will be referred as (CC) personnel and not as candidates for conversion to a permanent career or career-conditional appointment. 

Additional selections may be made within the same geographical location CDC-wide.

This announcement can also be used to recruit for positions that will require a detail to an International Organization such as the World Health Organization, UNICEF, etc.

 

CDC Financial Disclosure —OGE form 450
Holding ourselves to a higher standard; the Centers for Disease Control and Prevention inspires public confidence in its trust responsibilities and mission by maintaining high ethical principles. This position is subject to the confidential financial disclosure requirements of the Ethics in Government Act of 1978 (P.L. 95-521). Therefore, if selected, you will be required to complete a Confidential Financial Disclosure Report (OGE Form 450) to determine if a conflict or an appearance of a conflict exists between your financial interest and your prospective position with the agency. This Information will be required annually.

CDC is an Equal Opportunity Employer.

 

Duties

 

As a Health Scientist you will:

·Serve as a recognized authority or consultant for health programs and conducts scientific research to develop a national system(s) to monitor public health capacity and performance overseas.

·Identify and analyze public health issues and their impact on scientific operations that are critical to the public health community at large. 

·Analyze scientific investigation data utilizing new methodologies or existing techniques that have been extensively revised.

·Conduct major statistical studies or continuing projects that represent an important segment of the center's primary investigative program.

·Collaborate on projects/studies and coordinate efforts, as appropriate, with other program staff, other Centers for Disease Control and Prevention centers, other federal, state, local and international health agencies, and private and non-private organizations.

 

Travel Required

  • Occasional Travel
  • As required by the position

Relocation Authorized

  • Yes
  • May be authorized

Job Requirements

Key Requirements

  • U.S. Citizenship is required.
  • Background Investigation is required.

Qualifications

BASIC QUALIFICATIONS: 

Must possess a full 4-year course of study in an accredited college or university leading to a bachelor's or higher degree with major study in an academic field related to the health sciences or allied sciences appropriate to the work of the position.

In addition to meeting the basic qualification requirements, applicants must meet the specialized experience as stated below.

 

MINIMUM QUALIFICATIONS:

GS-13: Applicants must possess at least one year of specialized experience equivalent to at least the GS-12 grade level in the Federal Service. Specialized experience is experience which is directly related to the position which has equipped the applicant with the particular knowledge, skills and abilities (KSAs) to successfully perform the duties of the position to include experience planning, conducting, and analyzing scientific studies or surveys related to public health programs.

 

GS-14: Applicants must possess at least one year of specialized experience equivalent to at least the GS-13 grade level in the Federal Service. Specialized experience is experience which is directly related to the position which has equipped the applicant with the particular knowledge, skills and abilities (KSAs) to successfully perform the duties of the position to include experience providing scientific leadership in formulating, developing, implementing and evaluating scientific studies or surveys related to public health programs.

 

 

FOREIGN EDUCATION:

Education completed in colleges or universities outside the United States may be used to meet the education requirements. You must provide acceptable documentation that the foreign education is comparable to that received in an accredited educational institution in the United States. For more information on how foreign education is evaluated, visit:http://wwwdev.cdc.gov/employment/newhire/foreigned.html.

Conditions of Employment:

1. Security and Background Requirements: If not previously completed, a background security investigation will be required for all appointees. Appointment will be subject to the applicant's successful completion of a background security investigation and favorable adjudication. Failure to successfully meet these requirements may be grounds for appropriate personnel action. In addition, if hired, a background security reinvestigation or supplemental investigation may be required at a later time. Applicants are also advised that all information concerning qualifications is subject to investigation. False representation may be grounds for non-consideration, non-selection and/or appropriate disciplinary action.

2. E-Verify: If you are selected for this position, the documentation that you present for purposes of completing the Department of Homeland Security (DHS) Form I-9 will be verified through the DHS "E-Verify" System. Federal law requires DHS to use the E-Verify System to verify employment eligibility of all new hires, and as a condition of continued employment obligates the new hire to take affirmative steps to resolve any discrepancies identified by the system. The U.S. Department of Health and Human Services is an E-Verify Participant.

3. Direct Deposit: All Federal employees are required to have Federal salary payments made by direct deposit to a financial institution of their choosing.

 

 

4. All qualification requirements must be met by the closing date of the announcement.
5. One-year probationary period may be required.
6. Travel, transportation, and moving expenses may be authorized.
7. Bargaining Unit Position: No
8. Drug Screening Required: No
9. Recruitment Incentive may be authorized.

10. Relocation Incentive may be authorized.

11. Student Loan Repayment Incentive will not be authorized.
12. Promotion potential: No
13. Time in grade (TIG) must be met within 30 days of the closing date of the announcement.

Special Notes:  

·Although this announcement is advertised for multiple grade levels, it is not intended to convey any implication nor expectation that positions will be filled at all grade levels or locations.

·This announcement is being used to create an inventory of applicants for Health Scientist positions and will be used to fill immediate and future needs.

·Some positions may be filled as Permanent, Temporary Promotion or as Term appointments.

·Applicants are encouraged to apply early in order to maximize their employment opportunities. Your application will remain in the inventory of tentatively qualified applicants. Applicants that are among the best qualified will be referred to the selecting official for consideration as requests to fill vacancies are processed by the Human Resources Office. The first cut-off date for you to be referred will be May 17, 2017. Thereafter, additional referral lists will be generated throughout the open period as vacancies occur. If further evaluation or interviews are required, you will be contacted.

·This is an open continuous announcement. Qualified applicants will be considered as job opportunities occur and may or may not receive further notification regarding the status of their application.

·Term appointments may be shortened or extended up to a maximum of four years based on the needs of the agency without further competition. Subsequent employment for CDC positions must be through the appropriate competitive process or special employment program hiring authorities.

·Temporary promotions may be extended up to a maximum of five years based on the needs of the agency without further competition. 

·Supervisory position: This announcement may be used to fill supervisory or lead positions.


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Chemist

Date Posted:
5/6/2017

FDA

MD

Become a part of the Department that touches the lives of every American!  At the Department of Health and Human Services (HHS) you can give back to your community, state, and country by making a difference in the lives of Americans everywhere.  It is the principal agency for protecting the health of citizens.  Join HHS and help to make our world healthier, safer, and better for all Americans.

 This HHS Position meets the criteria outlined in OMB M-17-18 and is exempt from the hiring freeze.

 

 

This position is located in the Center for Drug Evaluation and Research (CDER), Office of Pharmaceutical Quality (OPQ), Office of Lifecycle Drug Products.

Who May Apply: Open to all United States Citizens.

Additional selections may be made within the same geographical area FDA-wide.

This is a TERM appointment Not to Exceed 2 years.

This TERM appointment does not provide a permanent career-conditional appointment or reemployment right to a previous permanent appointment held.  TERM appointments do not provide status in the competitive service.

NOTE:  The agency has the option of extending a term appointment up to the 4-year limit.

Additional selections may be made within the same geographical area FDA-wide.

 

Duties

 

As a Chemist you will perform the following duties: 

  • Evaluate identification and characterization of drug substance's physical, chemical, biological and mechanical properties and their impact on the drug product;
  • Evaluate manufacturing processes and facilities used by foreign and domestic manufacturers of drug substances and/or products;
  • Apply mastery of chemistry principles, practices and procedures including Process Analytical Technology (PAT) to determine the adequacy of testing for raw materials and intermediates, the control of manufacturing processes, and the testing of the finished dosage forms;
  • Participate in the facility inspections related to the evaluation of manufacturing processes and controls and in support of pre-approval and cGMP inspections.

 

Travel Required

  • Occasional Travel
  • Occasional Travel May Be Required

Relocation Authorized

  • No

Job Requirements

Key Requirements

  • U.S. Citizenship is required.
  • Only experience gained by closing date announcement will be considered.
  • Transcripts required.

Qualifications

 

In order to qualify for Chemist, GS-1320-12/13, you must meet the following:

Basic Qualification for Chemist, GS-1320-12/13:

Degree: physical sciences, life sciences, or engineering that included 30 semester hours in chemistry, supplemented by course work in mathematics through differential and integral calculus, and at least 6 semester hours of physics.

or

Combination of education and experience -- course work equivalent to a major as shown in A above, including at least 30 semester hours in chemistry, supplemented by mathematics through differential and integral calculus, and at least 6 semester hours of physics, plus appropriate experience or additional education.

Transcripts must be provided with your application for qualifications based on education.

In addition to the basic qualification requirements, applicants must meet the specialized experience as stated below.

Minimum Qualification for Chemist, GS-1320-12: Applicants must have one year of specialized experience, equivalent to the GS-11 level of difficulty and responsibility in the Federal service to include: 1) Evaluating drug substance synthesis, drug product  formulation design, or drug product manufacturing processes and associated control strategies; 2) Reviewing inspection reports, inspection data and analytical evidence, or scientific and technical data, for consideration of regulatory action; and 3) Evaluating inspection reports and scientific data in terms of compliance with applicable laws and regulations. 

Minimum Qualification for Chemist, GS-1320-13: Applicants must have one year of specialized experience, equivalent to the GS-12 level of difficulty and responsibility in the Federal service to include: 1) Participating in the review and analysis of chemical processes and/or formulation involved in the manufacturing of drugs; 2) Analyzing and evaluating written scientific and technical data in order to review drug applications and their amendments/supplements; and 3) Identifying problems and deficiencies within drug manufacturing processes.

 

 

If you are claiming education as any part of your qualifications for this position, you must submit an official transcript, unofficial transcript, or a list including courses, grades earned, completion dates, and quarter and semester hours earned. If you are using education completed in foreign colleges or universities to meet the qualification requirements, you must show that the education credentials have been evaluated by a private organization that specializes in interpretation of foreign education programs and such education has been deemed equivalent to that gained in an accredited U.S. education program. For further information, click on foreign education.

 

 

Conditions of Employment: 

1. Security and Background Requirements: Appointment will be subject to the applicant's successful completion of a background security investigation. Failure to successfully meet these requirements may be grounds for appropriate personnel action. If hired, a background security reinvestigation or supplemental investigation may be required at a later time. Applicants are also advised that all information concerning qualifications is subject to investigation. False representation may be grounds for non-consideration, non-selection or appropriate disciplinary action. 

2. E-Verify: If you are selected for this position, the documentation that you present for purposes of completing the Department of Homeland Security (DHS) Form I-9 will be verified through the DHS "E-Verify" System. Federal law requires DHS to use the E-Verify System to verify employment eligibility of all new hires, and as a condition of continued employment obligates the new hire to take affirmative steps to resolve any discrepancies identified by the system. The U.S. Department of Health and Human Services is an E-Verify Participant. 

3. Direct Deposit: All Federal employees are required to have Federal salary payments made by direct deposit to a financial institution of their choosing.  

4. Pre-employment physical required: No

5. Drug testing required: No

6. License required: No

7. Mobility agreement required: No

8. Immunization required: No

9. Bargaining Unit Position: Yes

10. All qualification requirements must be met by the closing of the announcement.

11. Financial disclosure statement required: No

 

Security Clearance

Q - Nonsensitive


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Biologist

Date Posted:
5/6/2017

FDA

MD

Become a part of the Department that touches the lives of every American!  At the Department of Health and Human Services (HHS) you can give back to your community, state, and country by making a difference in the lives of Americans everywhere.  It is the principal agency for protecting the health of citizens.  Join HHS and help to make our world healthier, safer, and better for all Americans.

 

 

Who May Apply:  Federal employees with career or career-conditional appointments in the competitive service; former Federal employees with reinstatement eligibility based on previous career or career-conditional appointments; displaced Federal employees requesting special priority selection consideration under the Career Transition Assistance Plan (CTAP) and the Interagency Career Transition Assistance Program (ICTAP); veterans who are preference eligibles or who have been separated under honorable conditions after 3 years or more of continuous active service; Military Spouses; PHS Commissioned Corps Officers; individuals eligible for VRA appointments (at the GS-11 and below grade levels); and individuals with disabilities.

PHS Commissioned Corps Officers interested in performing the duties of this position within the Commissioned Corps may apply online to this announcement.  Candidates will be referred to (CC) personnel and not as candidates for conversion to a permanent career or career-conditional appointment.

YOU MUST SUBMIT CTAP or COMMISSIONED CORPS DOCUMENTATION.

Status Candidates (current and former) must provide a copy of a recent SF-50, "Notice of Personnel Action" that indicates proof of status and time-in-grade eligibility. The SF-50 must include your position, title, series, grade, step, tenure, type of service (Competitive or Excepted) and career status (career or career-conditional).

This position is located in the Food and Drug Administration, National Center for Toxicological Research, Office of Research, Division of Biochemical Toxicology in Jefferson, Arkansas.

Additional selections may be made within the same geographical area FDA-wide.

 

Duties

The incumbent of this position will perform the following:

  • Responsible for researching rodent bioassays (rats and mice) and ancillary studies using biochemical, molecular, cell culture and microbiological techniques.
  • Conducts biochemical studies on the activation of chemicals to reactive metabolites, mechanisms of detoxification of reactive metabolites, mechanisms of interaction of reactive metabolites with cellular constituents, and/or characterization of toxicological effects. 

  • Implements rigorous standard operating procedures for all aspects of phototoxicity and photocarcinogenicity studies, including animal care and use, calibration of sophisticated solar light simulators and for documenting procedures for compliance. 

  • Prepares technical reports and manuscripts for the National Toxicology Program (NTP) and for publication in the scientific literature. 

  • Participate in conferences and seminars research biology.

 

Travel Required

  • Not Required

Relocation Authorized

  • No

Job Requirements

Key Requirements

  • U.S. Citizenship is required.
  • Time in Grade (TIG) must be met by the closing date of the announcement.
  • Background investigation maybe required.
  • Be sure to read the "How To Apply" section for all required documents.

Qualifications

 

In order to qualify for Biologist, 0401-12, you must meet the following: Basic Requirements and Specialized Experience as follows:

Basic Requirements:

A. Have a four year degree in biological sciences, agriculture, natural resource management, chemistry or related disciplines appropriate to the position. (You must submit your transcript(s) that demonstrates this coursework at time of application submission)

OR


B. Have a combination of education and experience -- courses equivalent to a major in biological sciences, agriculture, natural resource management, chemistry or related disciplines appropriate to the position. (You must submit your transcript(s) that demonstrates this coursework at time of application submission)
Have one year of specialized experience, equivalent to the GS-11 In the Federal service.

In addition to meeting the basic requirements stated above you must meet the specialized experience below:

Have one year of specialized experience, equivalent to the GS-11 In the Federal service, performing spectral calibrations on solar light simulators and actively participating in the conduct of in vivo and in vitro studies to determine the potential effects of test agents when applied to experimental animals in the presence of solar light.

NOTE: Volunteer experience may also be used as qualifying experience.

 

Documenting experience:  In accordance with Office of Personnel Management policy, federal employees are assumed to have gained experience by performing duties and responsibilities appropriate for their official series and grade level as described in their position description.  Experience that would not normally be part of the employee's position is creditable, however, when documented by satisfactory evidence, such as a signed memorandum from the employee's supervisor or an SF-50 or SF-52 documenting an official detail or other official assignment. The documentation must indicate whether the duties were performed full time or, if part time, the percentage of times the other duties were performed. It is expected that this documentation is included in the employee's official personnel record. In order to receive credit for experience in your resume that is not within the official series and grade level of your official position, you must provide a copy of the appropriate documentation of such experience as indicated above.

 

 

If you are claiming education as any part of your qualifications for this position, you must submit an official transcript, unofficial transcript, or a list including courses, grades earned, completion dates, and quarter and semester hours earned. If you are using education completed in foreign colleges or universities to meet the qualification requirements, you must show that the education credentials have been evaluated by a private organization that specializes in interpretation of foreign education programs and such education has been deemed equivalent to that gained in an accredited U.S. education program.  For further information, click on foreign education.

 

Conditions of Employment: 

1. Security and Background Requirements:  Appointment will be subject to the applicant's successful completion of a background security investigation and favorable adjudication.  Failure to successfully meet these requirements may be grounds for appropriate personnel action.  If hired, a background security reinvestigation or supplemental investigation may be required at a later time.  Applicants are also advised that all information concerning qualifications is subject to investigation.  False representation may be grounds for non-consideration, non-selection and/or disciplinary action. 
2. E-Verify:  If you are selected for this position, the documentation you present for purposes of completing the Department of Homeland Security (DHS) Form I-9 will be verified through the E-Verify System.  Federal law requires DHS to use the E-Verify System to verify employment eligibility of all new hires, and as a condition of continued employment obligates the new hire to take affirmative steps to resolve any discrepancies identified by the system.  The U.S. Department of Health and Human Services is an E-Verify Participant. 
3. Direct Deposit:  All Federal employees are required to have Federal salary payments made by direct deposit to a financial institution of their choosing.  
4. Pre-employment physical required: No
5. Drug testing required: No
6. License required: No
7. Mobility agreement required: No
8. Immunization required: No
9. A background investigation may be required.
10. Incentives may be authorized; however, this is contingent upon funds availability. If authorized, certain incentives will require you to sign a service agreement to remain in the Federal government for a period of up to 3 years. Note: This statement does not imply nor guarantee an incentive will be offered and paid. Incentives include the following: moving expenses, recruitment or relocation incentive; student loan repayment, superior qualifications appointment, creditable service for annual leave for prior non-federal work experience or prior uniformed military service, etc.
11. Bargaining Unit Position: Yes

Please be advised this position will be subject to FDA's strict prohibited financial interest regulation and therefore, may require the incumbent of this position to divest of certain financial interests.  Applicants are strongly advised to seek additional information on this requirement from the FDA hiring official before accepting this position.

 

Security Clearance

Public Trust - Background Investigation


Read the full job description

Interdisciplinary Scientist

Date Posted:
5/6/2017

FDA

MD

Job Overview

Summary

 

This HHS Position meets the criteria outlined in OMB M-17-18 and is exempt from the hiring freeze.
 
Become a part of the Department that touches the lives of every American!  At the Department of Health and Human Services (HHS) you can give back to your community, state, and country by making a difference in the lives of Americans everywhere.  It is the principal agency for protecting the health of citizens.  Join HHS and help to make our world healthier, safer, and better for all Americans.
 
The Center for Veterinary Medicine (CVM) is an internationally recognized, high performance, public health organization. Our mission is to protect human and animal health. To achieve this, CVM reviews animal drug applications for safety and effectiveness, monitors animal drugs, animal foods, and devices on the market, reviews food additives for safety and utility, and conducts research that helps FDA ensure the safety of animal drugs, food for animals, and food products made from animals. CVM fosters human and animal health by approving safe and effective products for animals and by enforcing applicable provisions of the Federal Food, Drug, and Cosmetic Act and other authorities. These include animals, from which human foods are derived, as well as pet (or companion) animals. 

 

 

Due to the immensity of its charge, CVM depends upon a diverse and dedicated workforce. We recognize the importance of multi-disciplinary teamwork in reaching superior and timely regulatory decisions therefore we foster an atmosphere where every employee's contribution is important. New concepts, ideas, and creative approaches to improve current operations and to meet existing and future challenges are encouraged. Our goal is to not only enable our employees to positively impact the Center today, but to prepare our workforce for the demands, responsibilities, and career opportunities of tomorrow.

Who May Apply:  Federal employees with career or career-conditional appointments in the competitive service; former Federal employees with reinstatement eligibility based on previous career or career-conditional appointments; displaced Federal employees requesting special priority selection consideration under the Career Transition Assistance Plan (CTAP) and the Interagency Career Transition Assistance Program (ICTAP); veterans who are preference eligibles or who have been separated under honorable conditions after 3 years or more of continuous active service; Military Spouses; PHS Commissioned Corps Officers; and individuals with disabilities.

PHS Commissioned Corps Officers interested in performing the duties of this position within the Commissioned Corps may apply online to this announcement.  Candidates will be referred to (CC) personnel and not as candidates for conversion to a permanent career or career-conditional appointment.

YOU MUST SUBMIT YOUR SF-50 (Notification of Personnel Action), CTAP, veteran documentation or Commission Corps documentation or your application will be considered incomplete.

This position is located in the Food and Drug Administration, Office of Foods and Veterinary Medicine, Center for Veterinary Medicine, Office of New Animal Drug Evaluation, Division of Manufacturing Technologies in Rockville, Maryland. 

 

Duties

 

The Division of Manufacturing Technologies evaluates the total manufacturing and control operations of a drug product as submitted in an application. As a Scientist in the Division of Manufacturing Technologies you will conduct scientific reviews of New Animal Drug Applications (NADAs), Master Files (MFs), Investigational New Animal Drug files (INADs) for technical information supporting the manufacturing and controls of an animal drug product. You will use regulatory knowledge and discretion to ensure review activities are aligned with laws, regulations (e.g., Good Manufacturing Practices), and policies which may require interpretation or adaptation. You will also collaborate and assist other scientists from industry, academia and/or government agencies in providing practical knowledge and expertise related to the manufacturing and controls of animal drug products.

As part of a Government-wide initiative to increase the efficiencies in the use of Federal real estate by creating new alternative office solutions, The Office of New Animal Drug Evaluation (ONADE) operates in a hoteling work environment.  Hoteling is an arrangement where employees reserve non-dedicated, non-permanent workspace at the duty station on an as needed basis and as required (when in person attendance is deemed important and regardless of need, no less than 2 days per pay period). ONADE provides the basic technology needed to effectively work in the Rockville office and in a teleworking location (e.g., laptop, monitors, webcam). Hoteling, along with a strong telework program and strong electronic communication and workflow tools, affords employees in ONADE the flexibility to balance work/life demands while contributing to our high performing organization.

 

Travel Required

  • Not Required

Relocation Authorized

  • No

Job Requirements

Key Requirements

  • U.S. Citizenship is required.

Qualifications

 

In order to qualify for Interdisciplinary Scientist, GS-0401/0403/1320-12, you must meet the following:

 

BIOLOGIST, GS-0401 BASIC REQUIREMENTS:  Possess a four year degree in biological sciences, agriculture, natural resource management, chemistry, or related disciplines appropriate to the position (must submit transcript) OR possess a combination of education and experience -- Courses equivalent to a major, as shown in above, plus appropriate experience or additional education.

 

MICROBIOLOGIST, GS-0403 BASIC REQUIREMENTS:  Possess a four year degree in microbiology; or biology, chemistry, or basic medical science that included at least 20 semester hours in microbiology and other subjects related to the study of microorganisms, and 20 semester hours in the physical and mathematical sciences combining course work in organic chemistry or biochemistry, physics, and college algebra, or their equivalent (must submit transcript) OR possess a combination of education and experience -- Courses equivalent to a major in microbiology, biology, chemistry, or basic medical science that includes courses as shown above, plus appropriate experience or additional education.

 

CHEMIST, GS-1320 BASIC REQUIREMENTS:  Possess a four year degree in physical sciences, life sciences, or engineering that include 30 semester hours in chemistry, supplemented by course work in mathematics through differential and integral calculus, and at least 6 semester hours of physics (must submit transcript) OR a combination of education and experience -- Courses equivalent to a major, as shown above, including at least 30 semester hours in chemistry, supplemented by mathematics through differential and integral calculus, and at least 6 semester hours of physics plus appropriate experience or additional education.

 

AND

SPECIALIZED EXPERIENCE REQUIREMENTS:  Have one year of specialized experience equivalent to the GS-11 grade level in the Federal service that includes conducting scientific analysis of data from drug or biological product related  research and/or experiments; evaluating the chemical/biological/microbiological ingredients in substances or biological products to determine the identity, strength, quality, and/or purity; and preparing, presenting, and/or defending findings on scientific research/experiments that focus on the chemical, biological and/or microbiological attributes in substances or biological products.  This experience must be reflected in your resume. Volunteer experience can also be used as  qualifying experience.

Documenting experience:  In accordance with Office of Personnel Management policy, federal employees are assumed to have gained experience by performing duties and responsibilities appropriate for their official series and grade level as described in their position description.  Experience that would not normally be part of the employee's position is creditable, however, when documented by satisfactory evidence, such as a signed memorandum from the employee's supervisor or an SF-50 or SF-52 documenting an official detail or other official assignment. The documentation must indicate whether the duties were performed full time or, if part time, the percentage of times the other duties were performed. It is expected that this documentation is included in the employee's official personnel record. In order to receive credit for experience in your resume that is not within the official series and grade level of your official position, you must provide a copy of the appropriate documentation of such experience as indicated above.

 

 

You must submit an official transcript, unofficial transcript, or a list including courses, grades earned, completion dates, and quarter and semester hours earned. If you are using education completed in foreign colleges or universities to meet the qualification requirements, you must show that the education credentials have been evaluated by a private organization that specializes in interpretation of foreign education programs and such education has been deemed equivalent to that gained in an accredited U.S. education program.  For further information, click on foreign education.

 

Conditions of Employment: 

1. Security and Background Requirements:  Appointment will be subject to the applicant's successful completion of a background security investigation and favorable adjudication.  Failure to successfully meet these requirements may be grounds for appropriate personnel action.  If hired, a background security reinvestigation or supplemental investigation may be required at a later time.  Applicants are also advised that all information concerning qualifications is subject to investigation.  False representation may be grounds for non-consideration, non-selection and/or disciplinary action. 
2. E-Verify:  If you are selected for this position, the documentation you present for purposes of completing the Department of Homeland Security (DHS) Form I-9 will be verified through the E-Verify System.  Federal law requires DHS to use the E-Verify System to verify employment eligibility of all new hires, and as a condition of continued employment obligates the new hire to take affirmative steps to resolve any discrepancies identified by the system.  The U.S. Department of Health and Human Services is an E-Verify Participant. 
3. Direct Deposit:  All Federal employees are required to have Federal salary payments made by direct deposit to a financial institution of their choosing.  
4. Pre-employment physical required: No
5. Drug testing required: No
6. License required: No
7. Mobility agreement required: No
8. Immunization required: No
9. A background investigation may be required.
10. Incentives may be authorized; however, this is contingent upon funds availability. If authorized, certain incentives will require you to sign a service agreement to remain in the Federal government for a period of up to 3 years. Note: This statement does not imply nor guarantee an incentive will be offered and paid. Incentives include the following: moving expenses, recruitment or relocation incentive; student loan repayment, superior qualifications appointment, creditable service for annual leave for prior non-federal work experience or prior uniformed military service, etc.
11. Bargaining Unit Position: Yes                                                                                                                                  12. Financial Disclosure Statement Required: No


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Health Communications Specialist

Date Posted:
5/6/2017

FDA

MD

Become a part of the Department that touches the lives of every American!  At the Department of Health and Human Services (HHS) you can give back to your community, state, and country by making a difference in the lives of Americans everywhere.  It is the principal agency for protecting the health of citizens.  Join HHS and help to make our world healthier, safer, and better for all Americans.
 
The Center for Tobacco Products (CTP) of the Food and Drug Administration (FDA) is responsible for implementing the Family Smoking Prevention and Tobacco Control Act. This law gives FDA authority over tobacco products by adding a new chapter to the Food, Drug and Cosmetic Act. The Tobacco Control Act gives FDA the authority to regulate tobacco products and manufacturers based on the best available science and CTP is responsible for both assessing and fostering that science-base. CTP's actions have significant public health and consumer protection impact, and are among the most important issues faced by the Agency in its long and distinguished history.

 

 

Who May Apply:  Federal employees with career or career-conditional appointments in the competitive service; former Federal employees with reinstatement eligibility based on previous career or career-conditional appointments; displaced Federal employees requesting special priority selection consideration under the Career Transition Assistance Plan (CTAP) and the Interagency Career Transition Assistance Program (ICTAP); veterans who are preference eligibles or who have been separated under honorable conditions after 3 years or more of continuous active service; Military Spouses; PHS Commissioned Corps Officers; individuals eligible for VRA appointments (at the GS-11 and below grade levels); and individuals with disabilities.

PHS Commissioned Corps Officers interested in performing the duties of this position within the Commissioned Corps may apply online to this announcement.  Candidates will be referred to (CC) personnel and not as candidates for conversion to a permanent career or career-conditional appointment.

YOU MUST SUBMIT YOUR SF-50, CTAP or COMMISSIONED CORPS DOCUMENTATION

This position is located in the Department of Health and Human Services (DHHS), Food and Drug Administration (FDA), Center for Tobacco Products (CTP), Office of Health Communication and Education (OHCE).

This vacancy is also being announced concurrently with vacancy announcement FDA-CTP-17-DE-1949937CH under competitive procedures.  Please review that announcement to see if you are eligible for consideration under competitive procedures.  NOTE:  Applicants must apply separately for each announcement in order to be considered.

Additional selections may be made within the same geographical area FDA-wide.

 

Duties

 

  • Applies communication strategies, theories, and practices for communicating with various audiences, particularly special populations including at-risk youth, multicultural youth, rural youth, and LGBT.
  • Evaluates public health problems, particularly those related to the use of tobacco product.
  • Supports senior staff in the development, testing, and timely dissemination of science- and audience-based tobacco control messages and other public health products.
  • Supports research and evaluation activities related to tobacco education campaigns.
  • Contributes to the efficient and effective management of program resources and administrative processes.

 

Travel Required

  • Occasional Travel
  • Domestic travel is required approximately 10% of the time.

Relocation Authorized

  • No

Job Requirements

Key Requirements

  • U.S. Citizenship is required.
  • Time in Grade (TIG) must be met by the closing date of the announcement.

Qualifications

 

In order to qualify for a Health Communications Specialist, GS-1001-11/12, you must meet the following:
 
Health Communications Specialist, GS-1001-11:
You must have at least one year of specialized experience equivalent to the GS-09 level in Federal service supporting the planning, implementation, and evaluation of tobacco education or other related campaigns, programs, and activities designed to achieve behavior change and other positive health outcomes.
OR
Have at least three full academic years of progressively higher level graduate education or Ph.D. or equivalent doctoral degree or L.L.M., if related. An academic year of graduate education is considered to be the number of credit hours that the school attended has determined to represent one academic year of full-time study. This determination is made based on normal course loads for a full year of study in the graduate program. If that information cannot be obtained from the school, 18 semester hours or 27 quarter hours should be considered as satisfying the 1 year of full-time study requirement.
OR
Have less than the full amount of graduate education described in "B" and less than the amount of experience described in "A," but have a combination of the type of graduate experience described in "B" and the type of experience described in "A". To combine education and experience, the applicant's total qualifying experience and total qualifying education will be determined as percentages. The two percentages will be added together and must equal at least 100 percent to qualify.
 
Health Communications Specialist, GS-1001-12:
You must have at least one year of specialized experience equivalent to the GS-11 level in Federal service creating strategies for tobacco control and public health communications programs, and analyzing public health problems, particularly those related to the use of tobacco or other related products.

Documenting experience:  In accordance with Office of Personnel Management policy, federal employees are assumed to have gained experience by performing duties and responsibilities appropriate for their official series and grade level as described in their position description.  Experience that would not normally be part of the employee's position is creditable, however, when documented by satisfactory evidence, such as a signed memorandum from the employee's supervisor or an SF-50 or SF-52 documenting an official detail or other official assignment. The documentation must indicate whether the duties were performed full time or, if part time, the percentage of times the other duties were performed. It is expected that this documentation is included in the employee's official personnel record. In order to receive credit for experience in your resume that is not within the official series and grade level of your official position, you must provide a copy of the appropriate documentation of such experience as indicated above.

 

 

If you are claiming education as any part of your qualifications for this position, you must submit an official transcript, unofficial transcript, or a list including courses, grades earned, completion dates, and quarter and semester hours earned. If you are using education completed in foreign colleges or universities to meet the qualification requirements, you must show that the education credentials have been evaluated by a private organization that specializes in interpretation of foreign education programs and such education has been deemed equivalent to that gained in an accredited U.S. education program.  For further information, click on foreign education.

 

Conditions of Employment: 

1. Security and Background Requirements:  Appointment will be subject to the applicant's successful completion of a background security investigation and favorable adjudication.  Failure to successfully meet these requirements may be grounds for appropriate personnel action.  If hired, a background security reinvestigation or supplemental investigation may be required at a later time.  Applicants are also advised that all information concerning qualifications is subject to investigation.  False representation may be grounds for non-consideration, non-selection and/or disciplinary action. 
2. E-Verify:  If you are selected for this position, the documentation you present for purposes of completing the Department of Homeland Security (DHS) Form I-9 will be verified through the E-Verify System.  Federal law requires DHS to use the E-Verify System to verify employment eligibility of all new hires, and as a condition of continued employment obligates the new hire to take affirmative steps to resolve any discrepancies identified by the system.  The U.S. Department of Health and Human Services is an E-Verify Participant. 
3. Direct Deposit:  All Federal employees are required to have Federal salary payments made by direct deposit to a financial institution of their choosing.  
4. Pre-employment physical required: No
5. Drug testing required: No
6. License required: No
7. Mobility agreement required: No
8. Immunization required: No
9. A background investigation may be required.
10. Incentives may be authorized; however, this is contingent upon funds availability. If authorized, certain incentives will require you to sign a service agreement to remain in the Federal government for a period of up to 3 years. Note: This statement does not imply nor guarantee an incentive will be offered and paid. Incentives include the following: moving expenses, recruitment or relocation incentive; student loan repayment, superior qualifications appointment, creditable service for annual leave for prior non-federal work experience or prior uniformed military service, etc.
11. Bargaining Unit Position: Yes


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Postdoc Liver Metabolism

Date Posted:
5/5/2017

Pfizer

MA

A career at Pfizer offers opportunity, ownership and impact. All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.



Role Description

We are seeking a highly motivated postdoctoral fellow to participate in the Pfizer WRD postdoctoral program. The postdoctoral fellow will work with mentors and Pfizer colleagues to investigate a key metabolic enzyme involved in carbohydrate metabolism and its role liver homeostasis and disease. Under the guidance of research mentors, the successful candidate will drive the project forward with individual effort and independent study. The postdoc candidate should be independent and highly motivated with a keen interest in metabolic disease and liver metabolism.



Responsibilities

The successful candidate will be able to: Design and perform studies and interpret results under the guidance of mentors.

* Develop and implement independent research ideas.

* Produce high quality data that will lead to first author publication(s) in high impact journals.

* Critically analyze experimental data, summarize and present results at internal and external meetings.

* Collaborate effectively with Pfizer colleagues in other disciplines.

* Ensure all tasks and responsibilities are performed according to scientific and ethical standards and correctly documented in lab notebook.

Requirements

Qualifications

* Recent PhD (0-1 yrs) in biology, biochemistry, pharmacology or related field with demonstrated productivity in independent research (first author publication submitted/published in a high quality peer-reviewed journal).

 

* Experience required in rodent handling

* Metabolic infusion/tracer experience preferred, not necessary

* Demonstrated proficiency in basic molecular and biochemical techniques required including some of the following: RNA/protein isolation from cells & tissues, qRT-PCR, Western blot, ELISA, immunostaining, flow cytometry, RNA-seq, proteomics.

* Experience in hepatocyte isolation from rodents preferred.

* Excellent written and oral communication skills.

PHYSICAL/MENTAL REQUIREMENTS:

Animal handling required, including rats and mice.

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS:

Weekend/evening work may be required as project dictates.

 


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Postdoc Single Cell Sequencing

Date Posted:
5/5/2017

AstraZeneca

MA

At AstraZeneca we believe in the potential of our people and you’ll develop beyond what you thought possible. We make the most of your skills and passion by actively supporting you to see what you can achieve. We need great people who share our passion for science and have the drive and determination to meet the unmet needs of patients around the world. If you’re curious about what science can do, then you’re our kind of person.  

Cancer is one of the greatest challenges facing medical science today. In our Oncology Team, you’ll push the boundaries of science every day to overcome that challenge. We’ve been at the center of some of the biggest breakthroughs in oncology. In lung cancer, for example, we’ve brought together complementary expertise to aid discovery and accelerate development in new medicines through a variety of partnerships and initiatives. We’re also early adopters of new technologies to support innovation, including CRISPR, genome editing techniques and a next-generation sequencing platform for companion diagnostics in oncology. But we’re not stopping there. With a world-class pipeline and some of the best experts in the industry, we’re in a great position to develop even more innovative therapeutic approaches.

Main duties and responsibilities

 

   Immunotherapy is changing the paradigm for the treatment of cancer. Myeloid-targeting drugs have the potential to decrease immunosuppression in the tumor microenvironment (TME), thereby enhancing the activity of recently approved immune checkpoint blockade therapeutics. In this post-doctoral role, you will focus on characterizing the immune infiltrate in tumor models and clinical samples using cutting edge single cell sequencing techniques. By providing better understanding of the range of myeloid cell types in the TME and differentiating the effects of AstraZeneca’s myeloid targeting-drugs on the immune response, you will provide insights into how to best use these drugs in the clinical setting.  

   Your primary objectives will be to develop expertise in generating and interpreting single cell transcriptomic data; to characterize the breadth of myeloid/lymphoid cell subtypes in the TME +/- different drug treatments of mouse tumor models; and to extend this knowledge to clinical samples.  

   You’ll have the opportunity to work with leading academic labs to develop expertise in single cell sequencing approaches and also generate clinically relevant data. As a member of a highly motivated and experienced multidisciplinary Oncology team you’ll share our focus on publishing cutting edge research and bringing new medicines to cancer patients.  

Requirements

   Essential requirements:  

 

       
  •      PhD and/or MD in relevant area of biology    
  •    
  •      Expertise with bioinformatic approaches to characterize heterogeneity and function in complex tissues based on RNASeq/transcriptomic data    
  •    
  •      Strong scientific background in immuno-oncology/immunology/myeloid biology    
  •    
  •      Strong publication track record    
  •    
  •      Familiarity with experimental design and execution of in vivo experiments to determine the effects of therapeutics on biological systems    
  •    
  •      Highly motivated, innovative and reliable with the ability to effectively solve problems    
  •    
  •      Flexible, collaborative and team-oriented mind set    
  •    
  •      Effective communication and presentation skills    
  •    
  •      Strong desire to learn and perform cancer research in an industry-academic collaborative setting.    
  •  

   To apply for this position, please click the apply link below.

   AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.  

   This is a 2 year Fixed Term Contract opportunity, plus 1 year which will be merit based. The role will be based at Waltham, MA with a competitive salary on offer. Please note if you have applied for this role previously, your application will still be considered, please do not re-apply.  

Opening date of advert: 3rd May 2017

 

Closing date of advert:  18th June 2017

   If you share our passion for scientific excellence, find out more atcareers.astrazeneca.com  

 


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Postdoc Organic Chemistry

Date Posted:
5/5/2017

J&J

CA

Description:
Alios BioPharma, Inc., a member of Johnson & Johnson's Family of Companies, is recruiting for an Organic Chemistry position in a drug discovery chemistry group located in South San Francisco, CA. This is a full-time position.

Johnson & Johnson's Family of Companies are dedicated to addressing and solving the most important unmet medical needs of our time, including: oncology, immunology, neuroscience, infectious disease, and cardiovascular and metabolic diseases. Driven by our commitment to patients, we develop sustainable, integrated healthcare solutions by working side-by-side with healthcare stakeholders, based on partnerships of trust and transparency.

We are seeking an energetic, well organized, team-orientated individual, with experience in a wide range of synthetic chemistries, who can work efficiently with limited oversight, and is able to adapt to the dynamic needs of the group.

As a postdoctoral fellow in a drug discovery chemistry group, you will work closely with a group of highly collaborative scientists. Focus will be placed on optimization of lead compounds for preclinical development.

Requirements


Qualifications:
•   Ph.D. in organic or medicinal chemistry with emphasis on synthetic chemistry.
•   0-3 years of experience after Ph.D. in the synthesis of compounds of biological interest.
•   Demonstrated ability to scout and troubleshoot synthetic routes.
•   Demonstration of good lab practices, with particular attention to safety.
•   Clear understanding of structural determination using NMR and Mass Spectral techniques as well as familiarity with various chromatographic analysis and separation including HPLC.
•   Familiar with chemistry literature search tools and experienced in using SciFinder and/or Reaxys.
•   Candidates must have the ability to work individually (independently) as well as on a team. Excellent interpersonal, organizational, and oral/written communication skills with the ability to thrive in a goal driven team environment are preferred.
•   A minimum G.P.A. of 3.0 out of 4.0 is strongly preferred.


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Postdoc PhD Tumor Immunologist

Date Posted:
5/5/2017

Pfizer

NY

A career at Pfizer offers opportunity, ownership and impact. All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.



Role Description

We are seeking a highly motivated scientist with a strong background in dendritic cell biology and immunology to be a Postdoctoral fellow in the Oncology Research Unit. The candidate will lead a research project on the mechanism of dendritic cell activation by different types of stimulation. The candidate will conduct basic immunological assay including FACS analysis and ELISPOT assay for evaluation of anti-tumor immune response. The ideal individual will have extensive experience in immunology and cell/molecular biology. Experience of tumor immunology area will be preferred. The candidate should have a proven track record of publication including at least one first-author high impact journal paper related with immunology topic. For more information on the Pfizer-Oncology Postdoctoral Program, please visit us www. PfizerOncologyPostdoc.com



Responsibilities

The ideal candidate will assume leadership of a basic research project and design, perform and interpret experimental data to understand mechanism of dendritic cell activation by a DNA-damaging agent. The candidate also will investigate change of tumor micro environment and anti-tumor immune response mediated by a DNA-damaging agent treatment in vitro and in vivo. The individual will demonstrate a high level of knowledge about dendritic cell biology and tumor immunology. The candidate will effectively collaborate with other members of the Oncology Research Unit and conduct research that leads to publication in high-impact journal.

Requirements

Qualifications

Qualified individuals should have a PhD degree in Immunology, Cell/Molecular biology, Cancer biology, or related field. The individual should have basic and/or advanced knowledge of Immunology and at least one first-author peer reviewed paper related with Immunology field. The candidate should be highly-motivated and able to work as a team player in a highly interactive and multi-disciplinary research environment.


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Postdoc Genomics

Date Posted:
5/5/2017

BioNano Genomics

CA

Based in San Diego, CA, Bionano Genomics® is a commercial company that has delivered an altogether better way of gaining a fully informed understanding of genomes. With our revolutionary new genome mapping platforms, the Irys® System and Saphyr™ System, researchers can conduct unique studies to gain a complete picture of genome biology, including structural variations that current tools fail to detect. Bionano provides researchers and clinicians with the most comprehensive, organized and actionable picture of a genome with unprecedented insights into how the individual components of genomes are ordered, arranged, and interact with each other.

This position is a unique ground floor opportunity to join a rapidly growing genomics technology company.

Bionano Genomics is searching for a postdoc to help develop several novel applications and technologies for use on the Bionano single molecule mapping platforms (Irys and Saphyr). The successful candidate will be self-motivated, well organized and have extensive experience with experimental design and data analysis. Next generation mapping (NGM) leverages long-range information derived from molecules in the megabase range, NGM is used for de novo assembly, and structural variation analysis. This position requires a hard-working, meticulous person with outstanding technical skills. The work will require skills in experimental design as well as bioinformatics for data analysis. The postdoc projects will include development of new assays and labeling methods and will focus on integration of NGS data with Bionano NGM data for downstream applications. Experience in genome assembly and variation analysis tools is a must. The successful candidate will be expected to participate in consortia projects, present results at scientific conferences and in peer review publications.

Primary Duties and Responsibilities
•   Design experiments
•   Analyze data using custom bioinformatics tools
•   Develop analysis methods and outputs for new applications
•   Work collaboratively with internal and external colleagues

Requirements

Required:
•   Experience in state of the art genomics technologies (e.g. short read and long read sequencing, sample prep technologies, especially linked read technologies)
•   Experience in NGS technologies and their application to de novo assembly and structural variation analysis
•   Experience with de novo assembly (Falcon, Canu, Supernova, etc.) and structural variation software.
•   Strong publication record
•   Recent PhD in genomic sciences, genetics, molecular biology or a related field.
Advantageous:
•   Basic programming with R, Python, Perl, etc.
•   Experience in epigenetics studies

Physical Demands and Work Environment
The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job.  Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

While performing the duties of this job, the employee may be required to sit; use hands to finger, handle, or feel and reach with hands and arms. The employee may occasionally be required to stand and/or move about the office. Specific vision abilities may be required by this job including close vision and ability to adjust focus.

Nothing in this job description restricts management’s right to assign or reassign duties and responsibilities to this job at any time.  This description reflects management’s assignment of essential functions; it does not proscribe or restrict the tasks that may be assigned.  This job description is subject to change at any time.

The successful candidate will join a fast growing, innovative team that is developing cutting edge technologies in a fast paced, collaborative environment. They will contribute significantly to developing novel tools for genomic analysis as part of an interdisciplinary team that places emphasis on extraordinary achievement.

Bionano Genomics is an equal opportunity employer. We offer a positive, diverse and exciting work environment with competitive salary and benefits and the potential for career growth.

To apply for this position please email your cover letter, resume, and salary requirements to hr@Bionanogenomics.com and reference job code RD023.


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Biomedical Specialist

Date Posted:
5/5/2017

ProPharma

INT

 

Richmond North Yorkshire

ProPharma Group is a service company which handles Medical Information enquiries, adverse events and product quality complaints from healthcare professionals and patients on behalf of pharmaceutical and healthcare companies.

We are a globally integrated service provider with enquiry handling centres in Richmond North Yorkshire, the USA, Australia and Japan.

 

The Company employs more than 300 Medical Information professionals and support staff around the World and is known for its quality, customer service and cost effectiveness. Based on the Company’s excellent reputation, ProPharma Group is the service provider that most pharmaceutical companies turn to when external Medical Information support is required.

 

The Current Vacancy

The In House title is Medical Information Officer.

We are currently looking for a highly motivated and organised graduate/professional with a life science degree to join our company as a Medical Information Officer due to our continuing success and growth in new business.To be successful in this role you will be a good team player and have excellent communication skills and attention to detail.

 

 

A full induction and ongoing training is provided to allow you to rapidly develop the skills required to become an effective Medical Information Officer, and to progress your career further in the Company for those with the necessary desire and aptitude.

 

Main Purpose of Job

To provide a high quality Medical Information Service in respect of designated clients/products.

 

Roles and Responsibilities

Supervision, mentoring and advice will be provided to support the Medical Information Officer in the conduct of the designated responsibilities listed below:

 

  • Providing a high quality medical information enquiry handling service by answering technical questions in respect of designated products in an accurate, efficient, confident and professional manner. Enquiries will be handled from standard responses available on ProPharma Group’s computer systems.  
  • Liaising with the more experienced members of the Medical Information team to provide answers to questions that cannot be answered from the standard responses available.                            
  • Recognising adverse events and defective product reports and handling and reporting these in strict compliance with Working Practices.              
  • Carrying out literature searches in Medline as required.                          
  • Liaising with the Administration Team for them to prepare Medical Information correspondence to confirm information provided over the telephone, or to respond to enquiries submitted in writing.
  • Logging all enquiries in an accurate, comprehensive and timely fashion in the Enquiry Handling Databases.
  • Complying with the specific Working Practices which have been agreed with designated clients.
  • Maintaining awareness of, and ensuring compliance with, the legal requirements and professional guidelines associated with the provision of medical information on behalf of the Pharmaceutical Industry.
  • Ensuring that the Confidentiality Statement within the Contract of Employment and Data Protection Legislation is adhered to at all times in respect of the data and property of ProPharma Group and its clients.
  • Working in a professional manner at all times with clients, customers, team members and management.

Ideal Candidate Profile

  • A human Life Sciences qualification is essential. Examples include science degress, biomedical science, nurses, pharmacists, pharmacy technicians and despensers and therapists including physiotherapists and psychologists.
  • Excellent written and verbal communication skills and computer literacy.
  • Sound planning, prioritising and organisational skills.
  • Accuracy and attention to detail.
  • Strong organisational skills.
  • Own transport essential as ProPharma Group is in a rural location with limited public transport.  

Employment terms and conditions

Terms and conditions of employment will be discussed in detail at interview, but the basic package on offer comprises the following:

  • 37.5 hours working week, Monday - Friday. Hours are normally 9am-5.30pm.  
  • Once appropriately experienced, there will also be a requirement, as part of an on-call rota, to provide call handling support outside of these hours via an out-of-hours mobile phone.
  • Salary will be commensurate with qualifications and experience.
  • 24 days holiday, increasing with length of service. 
  • Company Pension Scheme
  • Private Healthcare
  • Career progression opportunities

How to apply

To apply for this role please email your CV and covering letter to HR@EU.ProPharmaGroup.com or email us for an application form.

 

 


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Scientist I

Date Posted:
5/5/2017

Medimmune

MD

Poisition Description:
MedImmune is the worldwide biologics research and development arm of AstraZeneca. Here, you'll have the opportunity to make a difference in people's lives every day. As one of the world's premier biotechnology companies, our mission is centered on delivering life-changing products that advance world health, and help fight and cure disease. As a Scientist I/II in Gaithersburg, MD, you'll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients' lives.
We're constantly pushing the boundaries of science to deliver life-changing medicines to patients, with a passion for discovery and a pipeline to show for it. We're pioneering innovative research and exploring novel pathways across key therapeutic areas including oncology, respiratory, inflammation and autoimmunity, cardiovascular and metabolic disease, and infection and vaccines. And we're industry-leading in immunology, protein engineering and translational science. We offer a unique and strong collaborative network as part of the AstraZeneca family, as together we explore synergies between small and large molecules.
MedImmune has a dynamic environment that fosters collaboration and innovation. We attract top minds, and we nurture and build top talent.

Responsibilities:
MedImmune is seeking a versatile molecular biologist with virology/immunology experience to explore new technologies relevant to in vivo biologics expression and/or novel pulmonary drug delivery approaches. Potential areas of interest include viral vector based biologics expression platform (e.g. AAV, Ad, RNA viruses), nucleoside-modified RNA antigen expression platforms, and tissue targeted biologics drug delivery (e.g. airway, solid organs). The candidate will be part of a growing cross functional effort to identify novel biologics expression and delivery approaches to combat respiratory disease, and is expected to be creative and innovative in their approach. Supervisory duties may be involved in the future.

Requirements:
This position will be a lab-based, hands-on research position. The appropriate candidate should have strong experience in some of the following areas: molecular cloning, viral vector engineering for gene therapy (AAV experience is plus), nucleotide synthesis and formulation for tissue targeted delivery, protein chemistry, bioconjugation, immunoassays etc.
Strong motivation, attention to detail, ability to conduct high quality research, deal with complex scientific/biologic concepts and ability solve complex problems independently is expected. Must have a proven record to effectively plan and organize work activities and prioritize task completion in a timely fashion. Excellent written, verbal and presentations skills is required
This position will require innovation and an innovative researcher with solid technical skills. The candidate should have demonstrated problem solving skills and versatile research abilities. Prior experience working in the collaboration or in a multidisciplinary matrix environment is desirable.

Experience:
PhD in molecular virology, cell biology, immunology or related scientific discipline with 3+ years of post-degree relevant experience

To Apply:
To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience.

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.


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Scientist Molecular Virology

Date Posted:
5/5/2017

GSK

MD

Position Description:
Seeking an enthusiastic bench scientist with expertise in molecular virology and molecular biology, particularly RNA virology, to join a diverse team of vaccine scientists aiming to design, characterize, optimize, evaluate and select vaccine candidates while also supporting platform technology development.

Responsibilities:

  • Demonstrates a detailed fundamental knowledge in molecular virology and molecular biology, particularly RNA or adenovirus, as they apply to vaccine discovery and development
  • Have practical knowledge in virus genetic manipulation, molecular and biological characterization, virus-host interactions, or viral pathogenesis
  • Subject matter expert in most relevant fields involving the team
  • Has transversal overview of all related activities within the department
  • Leads vaccine development-related scientific investigations, and publishes the work in scientific journals and patent filings
  • Executes a wide range of experiments/technical studies/tasks independently based on protocol
  • Develop and executes new methods and protocols and proactively incorporates new technology or techniques into practice with minimal supervision
  • Performs complex data management tasks with minimal supervision
  • Interprets results and communicates to the supervisor and designs next logical step of experiments based on interpretation of results 
  • Prepares oral or written summaries of results with interpretation for projects/programs 
  • Independently writes specific technical sections of internal, external reports, and scientific papers

Basic Qualifications: 
BSc plus at least 3 years of experience OR MSc plus at least 1 year of experience in an industrial or government laboratory setting.

To Apply:
You can apply for this position by searching the requisition ID of WD115234 online at this link:
http://www.gsk.com/en-gb/careers/search-jobs-and-apply/


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Bench Scientist

Date Posted:
5/5/2017

Synectics

MA

his research contractor position is located at the department of BioMedicine Design in Client campus of Cambridge MA. This individual will work in the area of bispecific therapeutic protein express production in mammalian cells. The individual will perform mammalian cell culture, DNA transfection, and protein production analysis for supporting bispecific protein therapeutics discovery efforts. The individual will perform this function with supervision and will display initiative in learning new techniques.

 

 

 

Mammalian CHO/HEK293 transient expression experience is preferred,

Mammalian cell culture techniques,

DNA transfection techniques,

Basic knowledge in Molecular Biology,

Basic knowledge in protein analysis such as SDS-PAGE, aSEC, ProA, Mammalian cell culture, DNA transfection, Protein analysis


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Research Scientist Orthopaedics

Date Posted:
5/5/2017

Childrens Healthcare of Atlanta

GA

ob Summary

 

Plans and conducts experiments to increase the body of scientific knowledge on medical, neuroscience, or social behavioral related topics. Aims to improve knowledge of the underlying basis of health and disease. Carries out clinical research which investigates enhanced methods of prevention, diagnosis, and treatment of human disorders. Builds collaborations with physicians, PhDs, PharmDs, and other healthcare providers to conduct multidisciplinary studies that impact the overall wellbeing of infants and children. Analyzes study results and communicates findings through presentations at conferences and publications in specialist scientific, clinical, and medical journals.

 

EDUCATION

 

    • Doctorate in the required field

 

Certification Summary

 

    • No professional certifications required

 

EXPERIENCE*

 

    • 3 years of experience in developing and conducting scientific investigations and applying research principles, methodologies, and study design

 

PREFERRED QUALIFICATIONS*

 

    • 3 years of experience in applying for and achieving grant funding
    • Basic statistics (SPSS, SAS)

 

KNOWLEDGE SKILLS & ABILITIES*

 

    • Self-directed and motivated to work independently toward short- and long-term goals
    • Demonstrated ability in utilization of advanced methods, techniques, and procedures in the performance of scientific research involving multiple variables
    • Demonstrated ability in independent design, organization, and quality control of moderately complex but specific research projects within an integrated, multifaceted research program
    • Demonstrated ability in oversight of standard sub-projects as principal researcher
    • Demonstrated ability in direct participation in the development, writing, and presentation of abstracts, manuscripts, and posters as part of a research team
    • Good communication, organization, critical thinking, and interpersonal skills
    • Good computer skills, including working knowledge of a PC and Microsoft Office (Word, Access, Excel, and PowerPoint)
    • Knowledge of research regulations, methodology, principles, and procedures
    • Knowledge of current technological developments/trends in area of expertise

 

JOB RESPONSIBILITIES*

 

 

  • Evaluates, selects, and applies standard scientific techniques, procedures, and criteria to accomplish a variety of research assignments.
  • Makes preliminary selections and adaptations of scientific alternatives requiring the exercise of judgment.
  • Collects, analyzes, and interprets data.
  • Prepares statistical and narrative reports and/or graphs, including production of manuscripts and abstracts on selective projects for publication in scientific journals.
  • Serves as principal investigator and/or co-investigator on sub-projects of complexities consistent with above criteria.
  • Collaboratively and/or independently seeks funding sources and applies for funding to further the goals of the department’s research.
  • Designs, performs, and/or oversees experiments and data collection to ensure data integrity, quality control, and protocol compliance.
  • May manage operations and budget of a specific research unit.
  • Supervises, mentors, and guides staff and/or students engaged in associated research support activities.
  • Performs miscellaneous job-related duties as assigned.

 


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Data Scientist Oncology

Date Posted:
5/5/2017

Inspirata

FL

We are seeking a Data Scientist with deep expertise in Oncology, who will combine his or her knowledge of cancer-related data with technology, informatics, big data and analytics skills to help assemble a data platform that provides insights into the vast amounts of real world cancer data.

 

You will be responsible for all activities necessary to access, mine and categorize structured and unstructured cancer related data and for presentation of that data in the Company’s big data platform. You will be engaged in all data related activities, including data acquisition, design and implementation of data processing tools, data modeling, data architecture, data mining and statistical analysis to ensure the Company’s products access, organize and deliver accurate and meaningful information to researchers, clinicians and patients.

 

You must be comfortable digging into databases, health records, data architecture, data processing tools with software engineering colleagues to ensure that data is correctly captured, managed and delivered. You must be highly motivated, comfortable in a fast-paced entrepreneurial environment, with experience designing and developing highly dimensional data intensive products, strong product leadership and team working skills and an aptitude for new technologies.

 

RESPONSIBILITIES:

  • Align the Company’s business and product strategies with the required underlying data assets
  • Support the development and expansion of the Company’s oncology data assets to promote research, clinical and consumer use
  • Lead the definition, development, implementation and standardization of cancer data-related asset.
  • Provide expertise to fetch, process, cleanse, verify and QA raw data from various sources
  • Design data collection processes, data quality programs and analytic tools to optimize creation and delivery of clinical oncology content
  • Lead efforts to update, standardize and centralize disease factors such as cancer subtype, stage, therapy, and diagnostic factors
  • Select features, build, and optimize classifiers, using machine learning techniques or big data tools
  • Data mining, statistical analysis and visualization using state-of-the-art methods
  • Create automated anomaly detections systems and constant performance tracking
  • Collaborate with customers, product stakeholders and engineering to gather and document data-related requirements for accessing, cleaning, categorizing, organizing and mining data
  • Contribute expertise in medical informatics to support the utilization of the CIDT in research and clinical settings
  • Assist with the development, maintenance and adherence to policies, SOPs and data management plans related to data acquisition, use, security and compliance

 

REQUIREMENTS:

  • M.S. or Ph.D. in a technical, scientific or quantitative field
  • 5+ years’ experience in a healthcare setting and familiarity with pathology and oncology data and medical records
  • Excellent understanding of machine learning techniques and algorithms, such as Naive Bayes, SVM, Decision Forests, etc.
  • Strong experience with common data science toolkits, such as R, Weka, MatLab, etc.
  • Proficiency in using query languages such as SQL, Hive, Pig
  • Experience with NoSQL databases, such as MongoDB, Cassandra, HBase
  • Good applied statistics skills, such as distributions, statistical testing, regression, etc.
  • Good scripting and programming skills to perform ETL and data cleansing operations
  • Data-oriented personality with hands on experience using Relational models, Object Models, Hierarchy data models and network data models
  • Familiarity with medical ontologies, lexicons and tools required
  • Strong project management skills and demonstrated ability to influence, motivate and collaborate with software development colleagues

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Research Scientist Systems Biology

Date Posted:
5/5/2017

Sage Bionetworks

WA

Job description

We are recruiting a scientist with bioinformatics experience to lead integrative genomic analysis within one or more consortia of biologists and computational biologists.

 

Specific Responsibilities Include:

Job responsibilities include facilitating research between teams of scientists – for implementation of one’s own analyses, coordination of consortium-wide analyses, and cross-project evaluation and integration of results. These projects will advance our understanding of disease biology and refine disease diagnoses for use in targeted therapeutic intervention.

 

Specific responsibilities will focus on leading efforts in analysis of large-scale genomic data through the following activities:

• Coordinate data deposition and analytical outputs across multiple researchers

• Develop mechanisms to evaluate and combine outcomes across multiple lines of biological and statistical evidence

• Develop visualizations for model outcomes across multiple sources

• Automate the execution of new analysis methods using scripting and statistical programming

• Lead integrated analytical efforts and interpretation of results across collaborators within consortia.

• Perform research through well-informed biological and methodological strategic decisions on analyses of genomic and/or imaging datasets.

• Work with a high-degree of independence to complete and publish high quality research in a transparent, reproducible manner.

• Utilize internally developed software tools to manage collaborations and work closely with the software team to provide feedback on the development of these tools.

• Interface with software team to provide feedback on platform development including bug reports and feature suggestions.

 

  • Basic qualifications:

• Ph.D. or Masters degree in computer science, math, bioinformatics, or relevant scientific discipline – position will be commensurate with experience.

• 5 years of relevant work experience analyzing high-throughput genomics or imaging data or 2 years of experience analyzing remote sensor data.

• Expertise in one or more analytical programming languages (R, MATLAB, perl, python).

 

Additional skills/Preferences:

• Ability to manage a cross-disciplinary group of researchers in a collaborative project.

• Experience communicating advanced scientific concepts to a broad audience

• Track record of innovative publications in application of or methodological development of integrative analysis of high-dimensional data.

• Domain knowledge in neurobiology, neuropsychiatry or inflammatory disease.

Experience in the analysis of patient-contributed or remote sensor data.

Seniority Level

Mid-Senior level

Industry

  • Biotechnology
  • Research

Employment Type

Full-time

Job Functions

  • Research
  • Science

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Oncology Scientist/Medical Writer

Date Posted:
5/5/2017

National Comprehensive Cancer Network

PA

This position is responsible for the development, review, and update of scientific and clinical content for the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) and projects related to the NCCN Guidelines®, including but not limited to continuing education materials, conference reports, journal publications, and clinical content development for grant proposals, task force reports, and any NCCN Guidelines-related initiatives.

 

 

 

This position is located in Fort Washington, PA.

 

MAJOR RESPONSIBILITIES:

 

 

 

  • Perform PubMed literature searches; develop, review, edit, and update the assigned NCCN Guidelines
  • Track scientific literature with respect to designated NCCN Guidelines assignments
  • Attend NCCN Guidelines Panel meetings and web-based teleconferences
  • Participate in development and maintenance of the NCCN Guidelines in Guidelines Authoring Tool (GAT)
  • Develop and/or review clinical content for educational grant proposals including needs assessments, objectives, and faculty recommendations for NCCN educational programs
  • Develop, edit, and/or review clinical content for NCCN clinical information programs, including continuing education (CE) activities, conference reports, NCCN Guidelines Insights, JNCCN CE related articles, and external communication of Guidelines updates
  • Review permission requests and licensing of NCCN Guidelines information, including but not limited to print and electronic media, and integration into health-related information systems
  • Research and develop NCCN Task Force Reports based on panel presentations, discussion, and relevant scientific literature
  • Work on NCCN Guidelines-related initiatives

 

EDUCATION/RELATED EXPERIENCE:

 

  • PhD or equivalent experience with ability to evaluate clinical research
  • Experience in scientific/medical writing required
  • Experience in oncology strongly preferred

 

 

SKILLS AND ABILITIES:

 

  • Must have excellent writing skills and the ability to formulate scientific/medical information in a clear and concise manner
  • Must possess strong attention to detail
  • Must be proficient in MS Office products
  • Must have strong interpersonal communication skills and the ability to interact effectively with internal and external personnel at various levels

 

This position represents a unique opportunity to build a career with a premier organization. We offer competitive salary and excellent benefits.


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Sr. Scientist

Date Posted:
5/5/2017

Apex Life Sciences - Recruiter

CA

We are looking for a motivated and team-oriented individual who is passionate about revolutionary sequencing technology. As a Senior Scientist you will become an expert on the theory and operation of the new Single Molecule Sequencing platform and help take the machine from an advanced proof of principle to a production ready laboratory instrument. Working at the intersection of HW, SW, and chemistry, the candidate will be responsible for planning, executing and analyzing experiments to characterize system performance. The candidate must be self-motivated and able to work well in a team environment.

 

Job Requirements

 

  • Ph.D. degree in the physical sciences or engineering preferred
  • Extensive understanding of biochemistry, engineering, physics or related discipline
  • At least 3 years in an industry setting with experience performing thorough Verification and Validation product testing
  • Prior experience working with sequencing, single molecule, or microfluidic analysis systems highly desired
  • Previous experience in enzyme engineering and/or channel biology desired
  • Some computer scripting skills required (Python preferred)
  • Excellent written and oral communication skills
  • The candidate should be passionate and self-motivated with a strong desire to acquire on-the-job training

     

Demonstrated ability to work well in teams and across scientific disciplines is essential

 

Qualification

 

Become an expert on the operation of the Single Molecule Sequencing Platform

 

Design and execute experiments to further develop the nanopore sequencer, analyze and interpret the results

 

Help develop and guide research projects to maintain development timelines

 

Perform all work using best laboratory practices and maintain a well organized and concise record of work performed and progress made

 

email: dgilbrech@apexlifesciences.com


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Clinical Trials Results Analyst

Date Posted:
5/1/2017

ICF

MD

Clinical Trials Results Analyst 

(Job Number: 1700001534)

Apply at: https://icfi.taleo.net/careersection/icf_prof_ext/jobdetail.ftl?job=1700001534

 Social & Analytical Solutions / Health, Research, Informatics & Technology / Bethesda, MD

 Job Description:

The Health Research Informatics & Technology (HRIT) Division seeks a ClinicalTrials.gov Results Analyst to support our National Institutes of Health/National Library of Medicine (NIH/NLM) client. The National Institutes of Health, a part of the U.S. Department of Health and Human Services, is the primary Federal agency for conducting and supporting medical research (http://www.nih.gov/). The NLM collects, organizes, and makes available biomedical science information to scientists, health professionals, and the public (http://www.nlm.nih.gov/).

 ClinicalTrials.gov Background

ClinicalTrials.gov is a registry and results database of publicly and privately supported clinical research conducted in the United States and around the world. Both registration and results submission are accomplished through the Web-based Protocol Registration and Results System (PRS).Responsible parties commonly register trials and submit results prior to a journal publication. Unlike journal articles that are reviewed by both scientific colleagues and editors, data submitted to ClinicalTrials.gov are not peer-reviewed prior to posting, however specific review criteria must be met.

 The successful candidate for this position will be responsible for reviewing results data submissions to ascertain whether they meet minimal review criteria for posting on ClinicalTrials.gov.

*Information regarding the ClinicalTrials.gov database and reporting requirements can be found at http://clinicaltrials.gov/ct2/manage-recs/fdaaa

 Key Responsibilities:

  • Perform quality assurance/quality control reviews of clinical trial results submissions for consistency with review criteria
  • Clearly communicate (via record reviews, teleconferences, emails, workshops, etc.) with “responsible parties” (e.g., clinical trial sponsors, principal investigators, statisticians, etc.) to facilitate understanding of and adherence to submission requirements
  • Gain a working knowledge of the ClinicalTrials.gov Basic Results Data Element Definitions (http://prsinfo.clinicaltrials.gov/results_definitions.html) and ClinicalTrials.gov results review criteria (http://prsinfo.clinicaltrials.gov/ResultsDetailedReviewItems.pdf)
  • Create new documentation to help responsible parties submit their clinical trial results records
  • Devise and help implement strategies to improve the quality of submissions.
  • Participate in weekly team meetings with NLM staff to discuss process improvement
  • Perform general editorial proofreading

 Basic Qualifications:

  • PhD (or other degree at the level of a PhD, e.g. PharmD) from an accredited college in a biomedical science and/or mathematics-related discipline (epidemiology, biostatistics, neuroscience, pharmacology, biochemistry, etc.)
  • 1 year experience with standard mathematical concepts and statistics (correlations, trends, significance, etc.)
  • 1 year experience with standard quantitative measures for health studies

 Preferred Skills/Experience:

  • Background knowledge relevant to understanding and interpreting clinical trial data and statistics
  • 1 year experience with analysis and reporting of clinical trial data
  • Strong critical thinking, analysis, and problem-solving skills
  • Ability to critically appraise clinical trial design and methodology and to identify internal inconsistencies in clinical trial data reporting
  • Experience (via coursework and/or job duties) working with and interpreting the following concepts:
    • Mean, median, least square mean, standard deviation, range, inter-quartile range, confidence intervals, etc.
    • Frequency, incidence, proportion, percentage, rate, etc
    • Time-to-event measures
    • Parametric and non-parametric statistical tests, interpretation of p-values

 Professional Skills:

  • Ability to work within a team environment and contribute to consensus-based decision making
  • Ability to identify, analyze, and solve problems creatively and independently
  • Ability to handle multiple tasks simultaneously and shift priorities as directed
  • Ability to work efficiently with team members in a fast-paced environment
  • Excellent oral and written communication skills
  • Excellent interpersonal skills and ability to work with people at every level
  • General computer skills

ICF offers an excellent benefits package, an award winning talent development program, and fosters a highly skilled, energized and empowered workforce. 

ICF is an equal opportunity employer that values diversity at all levels. (EOE – Minorities/Females/ Protected Veterans Status/Disability Status/Sexual Orientation/Gender Identity)

 Working at ICF

Working at ICF means applying a passion for meaningful work with intellectual rigor to help solve the leading issues of our day. Smart, compassionate, innovative, committed, ICF employees tackle unprecedented challenges to benefit people, businesses, and governments around the globe. We believe in collaboration, mutual respect, open communication, and opportunity for growth. ICF—together for tomorrow.

 About ICF

ICF (NASDAQ:ICFI) is a global consulting and technology services provider with more than 5,000 professionals focused on making big things possible for our clients. We are business analysts, policy specialists, technologists, researchers, digital strategists, social scientists and creatives. Since 1969, government and commercial clients have worked with ICF to overcome their toughest challenges on issues that matter profoundly to their success. Come engage with us at icf.com.

 Primary Location: United States-Maryland-Bethesda


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Science Education Fellow in Physics

Date Posted:
4/25/2017

Stanford

CA

The Physics Department at Stanford University is seeking applications for a Science Education Fellow in Physics to support committed faculty in implementing an effective transition of physics courses to an active learning format. Fellows will typically have a recent PhD in physics and a keen interest in how learning works and how to improve it. Experience in facilitating interactive learning is desirable. The Fellow will join a cohort of Science and Engineering Education Fellows, including a current Fellow in Physics. The Fellow will be provided with training and with opportunities to engage in courses in a meaningful way, that will help to prepare the Fellow for a possible career in teaching and education. The Fellow will typically support one course per quarter in its initial transition to active learning; the course may be at any level or in any of the areas taught in a standard undergraduate physics curriculum.

A Fellow’s role will typically include the following elements in the quarters before, during, and after the course is taught: research and collect learning goals and existing active learning materials; facilitate the identification, development, and/or improvement of learning goals for the course; research and develop measures of students’ prior knowledge; work with the faculty instructor to develop activities, problem sets, pre-class preparation assignments, and other curricular materials that target the learning goals; co-teach a fraction of in-class activities, or one section (of three) per week; use Stanford resources to develop instruments to assess the effectiveness of different elements of the course and incorporate corrections; document and archive course materials using modern sustainable techniques that facilitate collaboration and sharing with other faculty; and serve as a resource in the department for other teaching-related projects. In addition to these duties, Science Education Fellows in Physics can take advantage of opportunities to organize and teach a summer course of their own, for their own professional development and credentials.

The appointment begins July 31, 2017, for a two-year term that is renewable for one additional year depending on programmatic need and job performance. Starting annual salary will be $70,000 with an additional supplement of up to $2,000/year that can be used for professional development opportunities and work-related expenses.

Applicants should submit the following materials: a letter that addresses qualifications including any relevant experience in teaching and course development, and knowledge or expertise in physics education, learning, and pedagogy; a current curriculum vitae; a teaching statement; and a summary of student, peer and/or other teaching evaluations. Application materials should be submitted using Academic Jobs Online.  https://academicjobsonline.org/ajo/jobs/9051

In addition, applicants should arrange for three letters of recommendation to be submitted by the reference writers through the Academic Jobs Online website. At least one letter writer should address the applicant’s experience or qualifications in teaching. If the applicant has not yet completed the Ph.D., one letter writer should address the status of dissertation progress toward completion by the end of June 2017.

Applications will be reviewed beginning May 1, 2017.

For further information about the position, send questions to physics-educ-fellow-info@lists.stanford.edu

Stanford University is an affirmative action and equal opportunity employer, committed to increasing the diversity of its workforce. It welcomes applications from women, members of minority groups, veterans, persons with disabilities, and others who would bring additional dimensions to the university's research and teaching mission.

- See more at: https://chroniclevitae.com/jobs/0000364613-01#sthash.duO9BJy4.dpuf


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Graduate Professional Development Career Advisor

Date Posted:
4/25/2017

Johns Hopkins

MD

The Graduate Professional Development Career Advisor will provide direct career advising and workshop delivery to graduate and PhD students in the Whiting School of Engineering’s Applied Mathematics and Statistics (AMS) program. To meet this goal, the Advisor will identify, create, and implement enhanced career advising and programming for AMS graduate/PhD students, collaborate with faculty in order to assist students in AMS in their professional development and interaction within industry, and develop and maintain connections between these programs and employers.
The Advisor will work closely with colleagues at the Johns Hopkins University Career Center, based on the Homewood Campus, reporting jointly to the AMS Senior Administrator and to the Executive Director of the Homewood Career Center.
Essential Duties and Responsibilities: For the following activities, this position will report to the Senior Administrator of AMS.

  • Collaboration, Outreach, and Strategic Planning
  • Discipline-specific employer relations:
  • Establish and maintain connections with industry and governmental agencies.
  • Establish and maintain a placement inventory of alumni; devise strategies to engage alumni.
  • Collaborate and coordinate employer relations outreach, programming and events with the Homewood Career Center.
  • Develop and conduct surveys with students, AMS alumni, and employers to analyze trends and to identify gaps and opportunities. Develop long-term sustainable strategies for discipline-specific career development opportunities for students.
  • Organize discipline-specific networking events.
  • Travel domestically to maintain industry and alumni relationships.

Coaching and Mentoring:

  • Provide discipline-specific career advising, for such disciplines as financial mathematics, data mining, operations research etc., to graduate and PhD students in the context of today’s industrial environment.
  • Develop and implement comprehensive discipline-specific professional development programming (alumni panels, current student internship presentations, etc.)
  • Coach individuals and groups to develop professionally and attain their career goals, utilizing coaching techniques and resources that meet the needs of diverse populations (international students and underrepresented minorities).
  • Facilitate student exploration of their skills, interests, values and experiences in order to create a job search strategy targeted to their discipline of interest.
  • Create and deliver workshops on a wide variety of career content areas including resume or CV writing, cover letter writing, creating a job search strategy, practice interviewing and networking.
  • Make recommendations and highlight courses available and appropriate for professional development.
  • Collaborate and coordinate student programming and events with the Homewood Career Center.

Program Management/Administration:

  • Maintain social media presence including utilizing social media to keep in touch with alumni and promote the master’s programs; maintain AMS career content on departmental website.
  • Manage AMS Career Development budget.
  • Hire student workers and oversee projects assigned to them.
  • Collaboration with Homewood Career Center and Other University Offices - For the following activities, this position will report to the Executive Director of the JHU Career Center.
  • Collaborate with the Employer Relations team at the Homewood Career Center when identifying and reaching out to employers to ensure coordination across JHU.
  • Partner with colleagues at the Homewood Career Center and in the Office of International Services to create programming and services specific to the challenges international students face in fellowship applications and job searches.
  • Coordinate strategic activities and programming with Homewood Career Center staff to ensure alignment, encourage coordination, identify the intersections of career services initiatives, and ensure consistent delivery of services.
  • Manage and track relevant data including internships, percentages of students doing internships, length of internships, trends, using career services management software where applicable. Share with colleagues at Homewood Career Center and other university administrators regularly and as requested for reporting purposes.
  • Working with colleagues at the Homewood Career Center and elsewhere around the university, build and maintain a network of professionals and alumni across varied careers who can attend networking and career exploration events.
  • Collaborate with Homewood Career Center colleagues to design, plan career development activities and events that promote personal and professional development in collaboration with students, advisors, faculty, alumni and others as relevant.
  • Partner with Homewood Career Center colleagues to establish and maintain connections with industry, governmental and non-governmental agencies.
  • Partner with Homewood Career Center and Development & Alumni Relations colleagues to establish and maintain a placement inventory of alumni; devise strategies to engage alumni.
  • Cultivate and strengthen relationships with colleagues across units, including, but not limited to, academic departments, academic advising, student affairs, and international services.



Qualifications

Education and Experience:
Master’s degree required. PhD preferred. Three-five years of experience required in higher education or in an industry related field (such as finance, banking, information technology, and health care).
Abilities and Skills

  • High proficiency in the use of traditional and online resources (e.g. LinkedIn) for career development.
  • Knowledge of the role of applied mathematics and finance in industry (strongly preferred).
  • Experience working with international students whose first language is not English (strongly preferred).
  • Confident, resourceful and self-directed individual with strong interpersonal skills, high emotional intelligence, and excellent oral and written communications skills.
  • Demonstrated capacity to work effectively with persons from diverse backgrounds to promote an inclusive campus and community culture.
  • Demonstrated skill in fostering new institutional relationships, and marshaling professional networks with faculty, senior administrators, employers and alumni.
  • Demonstrated experience in a higher education environment involving students, employers and/or alumni. Preferred experience in advising or mentoring students.
  • Ability to make decisions and work independently and to collaborate as a member of a team.
  • Knowledge of US immigration regulations as they affect employment of international students (CPT, OPT, etc.).

Additional Requirements:

  • Work occasional evenings or weekends as needed.
  • Some domestic travel may be required.



Preferred Qualifications

  • Significant experience working with international populations.
  • Teaching and/or training experience
  • Expertise and experience in presenting and training of large groups
  • Experience as a recruiter or with a professional placement firm.



NOTE: The successful candidate(s) for this position will be subject to a pre-employment background check.

If you are interested in applying for employment with The Johns Hopkins University and require special assistance or accommodation during any part of the pre-employment process, please contact the HR Business Services Office at 443-997-5100. For TTY users, call via Maryland Relay or dial 711.

Note: Job postings are updated daily and remain online until filled. See more in our FAQ .
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Assistant Director of Graduate Education

Date Posted:
4/25/2017

University of Virginia

VA

The School of Engineering & Applied Science (SEAS) at the University of Virginia invites applications for the position of Assistant Director of Graduate Education. The Assistant Director works with the Director of Graduate Education and the Graduate Programs Office toward the planning, development, and implementation of SEAS-wide programs and initiatives that support UVA Engineering graduate students.  This position will also work with the Center for Engineering Career Development to provide career advising for graduate engineering students and postdocs.

The successful applicant will possess excellent communication and interpersonal skills, and a strong desire to work with students, faculty, and administrators from across the School and University.  Broad knowledge of higher education policies and procedures, and significant experience with advising and mentoring graduate students is preferred.  Organizational and analytical skills are highly desired, as is a Ph.D. or terminal degree in any STEM field or in higher education.

 

Duties

Graduate Student Affairs and Recruitment (50%)

  • Work with the Director of Graduate Education to implement strategies and policies related to and impacting graduate affairs in SEAS
  • Help develop and execute a pro-active, year-round graduate student recruitment program that will include activities such as attendance and recruitment at key conferences, the planning and organizing of on-Grounds graduate recruitment events, and collaboration in the development of effective and up-to-date marketing materials
  • Assist in the development and implementation of strategies and initiatives to increase under-represented groups in the SEAS graduate student body
  • Gather, review, and report on graduate student data (e.g. applications, admissions, retention, diversity, and first destination outcomes)
  • Along with the Graduate Programs Office, oversee the content in the Graduate Record and on the SEAS Graduate website
  • Organize new graduate student orientation
  • Perform other duties and special projects as needed
  • Assist the Director of Graduate Education in developing programs to prepare students to be professionals and leaders in their fields.

 

Career and Professional Development (50%)

  • Advise students on career development, including self-assessment, career decision-making, CV/resume critiques, and job search strategies (both academic and non-academic). 
  • Assist graduate students in designing personalized professional development plans
  • Create and present career development events and workshops including how to approach academic and non-academic job searches, networking, CV and resume writing, interviewing, salary negotiation, and job offer decision making
  • Build relationships with alumni and professionals with the goal of expanding the career connections for graduate students and to strengthen our relationships with potential employers
  • Plan and organize programs that connect employers and alumni with students, including networking events, career panels and employer site visits
  • Develop relationships and collaborate with Engineering faculty, staff and the career services community across Grounds
  • Develop procedures to effectively evaluate programs and student services for graduate students. ?Analyze data and prepare statistical reports as needed.
  • Research program trends and challenges at peer institutions and make informed recommendations for programming. Attend annual conference for Graduate Career Consortium and related events.
  • Help develop appropriate internship and experiential opportunities for graduate students.
  • Assist graduate students in securing employment post-graduation, including post-doctoral positions, faculty positions, entrepreneurship and roles in government and provate industry.
  • Collaborate with the Director of Communications to promote our PhD students to faculty and Deans at other institutions

 

Application

To apply, visit https://jobs.virginia.edu/applicants/jsp/shared/frameset/Frameset.jsp?time=1492805720433. Reference job # 0620784.  Complete a Staff Application online, attach a cover letter, resume, and contact information for 3 references. The position will remain open until filled.  Any questions may be sent to shannon.barker@virginia.edu.

 

The University of Virginia is an equal opportunity and affirmative action employer.  Women, minorities, veterans, and persons with disabilities are encouraged to apply.

 

- See more at: https://chroniclevitae.com/jobs/0000366181-01#sthash.a721GNi7.dpuf


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Medical Writer !

Date Posted:
4/25/2017

ICON plc

PA

Description

 

This is an exciting opportunity to work within a fast-paced, environment with a team committed to being the best strategic medical communications agency in the world by leading the industry in quality, service, and innovation. At CHC Group, our value is our people, who consistently deliver the highest-quality work to our clients.

 

The Medical Writer position is an entry level position ideally suited for those looking to pursue a career in medical writing.

 

As a Medical Writer you are responsible for developing outlines, manuscripts, abstracts, scientific posters, and slide presentations across one or more therapeutic areas. The MW works closely with other Editorial and Client Services team members to meet client expectations, budgets and timelines.

 

Who Are We?

 

Through the recent acquisition of CHC Group and MediMedia Managed Markets (MMMM) LLC, ICON plc has strengthened its expertise in scientific communications and market access. ICON is a fast-growing global provider of outsourced development services to the pharmaceutical, biotechnology and medical device industries, known for its innovative approach. ICON’s core commercialization and outcomes capabilities coupled with the strategic consultancy services of CHC Group and MMMM, has created the industry’s most integrated product development, clinical communication and market access solution. This means more growth and career opportunities for our current and future employees!

 

What’s In It For You?

 

We provide our Medical Writers with a strong benefits package that includes a comprehensive health plan, retirement plans, competitive pay, vacation, and an annual incentive plan to reward performance.

 

We have a friendly environment where you can be fully engaged, motivated and rewarded. We allow you to shine because it enables us to achieve our goals. Our employees are our best asset and we encourage upward mobility by enabling them to realize their potential within a performance culture that is demanding and exciting.

 

To Succeed You Will Need

 

  • Advanced degree in life sciences (PhD, PharmD, or MD preferred, or proven record of excellence in the position)
  • Gracious and proactive ability to interact with clients
  • Ability to meet or beat deadlines every time
  • Must possess a high level of attention to detail

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Scientist II Cancer Immunology

Date Posted:
4/25/2017

Revolution

CA

REVOLUTION Medicines is an exciting, early stage biotechnology company that discovers and develops innovative drugs for cancer patients directed toward frontier oncology and immune-oncology targets.  The company draws inspiration from evolution and natural products that are inherently rich with biological function. REVOLUTION Medicines deploys an innovative toolkit including REVBLOCKS™, an integrated suite of rapid, agile, and modular synthesis methodologies applied to simple chemical “building blocks,” and the REVEAL™ computational platform, which uses evolution’s lessons to inform selection of chemical scaffolds guide drug design for non-classical drug targets. As a new member of the RevMed team, you will join other outstanding scientists who are helping lead our efforts in the discovery and development of new medicines for unmet needs in cancer.

 

The Opportunity:

As a key player in our biology team, you will:

  • Be a critical member of the cancer biology group and multi-disciplinary research project teams

  • Be accountable to the Head of Biology and Research Team Leads for performing cutting-edge cellular immunology research by integrating knowledge from tumor immunology and immunotherapy to support development of novel therapies.

  • Independently design and execute experimental strategies using cellular and molecular immunological techniques to investigate target biology and therapeutic mechanisms of action.

  • Develop novel in vitro or ex vivo assays systems to support characterization of novel therapies in in vivo immuno-oncology models.

  • Manage and analyze experimental data and present experimental results at internal meetings and scientific conferences.

  • Establish collaborations with leading academic research groups.

 

Required Experience, Skills, and Education:

  • Ph.D. degree in immunology, cancer biology, cell biology or a related discipline, with 2+ years of post-doctoral or relevant industry experience and demonstrable track record of excellence in tumor immunology and/or immunotherapy.

  • Strong track record of research productivity as evidenced by high-quality, impactful publications, preferably in the field of cancer biology or tumor immunology.

  • Extensive hands on experience in ‘state of the art’ immunology techniques including multi-parameter flow cytometric analyses, cytokine analysis, functional assays, imaging, cell biology and molecular biology.

  • Previous experience with tumor models would be a plus. Knowledge of models that interrogate and modulate cells and mediators of the innate and adaptive immune system would be an advantage.

  • Rigorous, quantitative and detail-oriented experimentalist with a desire to continue in a laboratory-focused role

  • Excellent written and verbal communication skills.

  • Demonstrated ability to multi-task, prioritize options, anticipate challenges, and execute on goals as a member of an interdisciplinary team is extremely important.

  • Thrives in a collaborative team setting and is driven by a desire to deploy innovative approaches and technologies in a high energy start-up environment. 


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Scientific Data Analyst - Informatics

Date Posted:
4/25/2017

Nurix

CA

We are seeking a highly skilled and motivated Scientist to lead and support implementing data assessment and decision systems for biological assays: High-throughput Screening (HTS), in vitro and cellular, in vitro and in vivo ADME and toxicology. This person will establish and support the models and processes used to assess the quality of data, the statistical methods to apply, the criteria for selection of hits, and the capture of decisions why particular methods were selected. This individual will work closely with a team of interdisciplinary scientists and will provide insights to other scientist in order to leverage scientific and information systems to record and drive team decisions. The ideal candidate will be self-driven, resourceful, very organized and focused, and enjoy working in a dynamic team environment.

Primary Functions

  • Understand raw data from low-throughput in vitro and high-throughput screening (HTS) assays
  • Create automated scripts to process assay data into analysis-ready results including consideration to outliers, edge effects, controls, and methods to calculate IC50 and EC50
  • Assist scientists with statistical analysis and interpretation of results into decisions, including pass/fail of target hit, compound confirmation, and activities in counter screens
  • Develop, refine, and deploy models to visualize single and multiple data sets in order to streamline the decision-making process with scientists and leaders
  • Present meaningful, easy-to-understand, consistent visualizations incorporating statistical assessment of data quality with comparisons among methods, data sets, and assay conditions
  • Analyze historical trends across targets and share insight into classes of action and promiscuity
  • Discuss/Document workflow and requirements of scientists into action items
  • Assist in the proper storage and retrieval of information to/from databases

Qualifications

  • Ph.D. in Computational Biology, Computer Science, Bioinformatics, Statistics, or related field with 3+ year’s post-degree experience. Master’s degree candidate with 8+ years’ experience would also be considered.
  • Experience with multivariate statistical techniques, algorithms, and packages to handle systematic and random error in multiple types of biological experiments and implement them in data analysis workflow
  • Knowledge of appropriate models to filter and fit multi-dimensional, chemical and assay data as well as assess the quality of the data being reviewed
  • Expertise in comprehensive data analysis with commercial scripting tools such as Pipeline Pilot and decision tools such as Dotmatics’ Vortex and TIBCO Spotfire
  • Ability to use statistical packages such as R, JMP, Minitab, and ProMV
  • Ability to code algorithms using formal (e.g., Java) or scripting (e.g., Python) languages
  • The successful candidate will be aligned to Nurix’ culture and values; he/she will be team oriented and highly collaborative with a hands-on approach
  • The candidate should be enthusiastic, driven, have the ability to work independently and thrive in a dynamic start-up environment

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Scientist I Affinity Selection, Library Discovery

Date Posted:
4/25/2017

Nurix

CA

Position
We are seeking a highly skilled and motivated Scientist with expertise in protein sciences and affinity selection methodologies to join Nurix’s Library Discovery team. Nurix is devoted to unlocking the therapeutic potential of the ubiquitin proteasome system (UPS) in the areas of oncology and immuno-oncology, by utilizing mechanistic and structural insights to guide drug discovery efforts.

Primary Functions

The successful candidate will utilize DNA encoded libraries to identify novel, physiologically relevant chemical matter for a variety of targets within Nurix’s discovery pipeline. This person will also play a key role in discovery by evolving the standard paradigm of encoded library selection toward more extensive and mechanism-directed selection campaigns that exploit existing biophysical and mutation information. This individual will work closely with an interdisciplinary team of discovery scientists, all of whom have regular opportunities present findings to the project team and senior management. The candidate should have a strong desire to learn new techniques and the ability to incorporate new methodologies into their work. The ideal candidate will be self-driven, resourceful, very organized and focused, and enjoy working in a dynamic team environment.

Qualifications

  • Ph.D. in Biochemistry or related field with 0-3 years post-degree industry experience.
  • Expertise in DNA encoded library affinity selection or related methodologies (phage display or SELEX, etc…).
  • Experience in using biophysical techniques to analyze protein-protein interactions as well as protein-small molecule interactions.
  • Hands on experience performing biochemical assays.
  • Experience with protein expression and purification, ideally with multiprotein complexes.
  • A strong track record (publications or industry experience) with excellent interpersonal skills and ability to work in a team environment.
  • The successful candidate will be aligned to Nurix’s culture and values; he/she will be team oriented and highly collaborative with a hands-on approach.
  • The candidate should be enthusiastic, driven, and have the ability to work independently and thrive in a dynamic start-up environment.

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Scientists Biology

Date Posted:
4/25/2017

Pliant

CA

Description:

Pliant Therapeutics is an early stage biopharmaceutical company focused on the discovery and development of novel therapies for fibrotic diseases. Founded by Third Rock Ventures with world-renowned academic thought leaders, Pliant is raising the bar for progress to meet unmet medical needs for patients and physicians. The company’s focus is on mechanism-based intervention in the fibrotic process using small molecules. The Company is seeking passionate, creative and dedicated scientists to join our team and contribute to our mission.

Position Overview

Immediate openings are available for Scientists/Sr. Scientists with experience in the fibrosis/inflammation area. Experience in cell signaling and previous research industry experience in drug development is a plus. This individual will join a dynamic and growing multidisciplinary team focused on discovery and advancement of new drug candidates and disease biomarkers. The primary responsibility of this position will be related to the field of fibrosis, notably in the discovery of novel signaling pathways.

Responsibilities:

  • Plan and execute experiments related to the evaluation of novel targets and signaling pathways.
  • Make detailed observations, record and analyze data.
  • Troubleshoot experiments.
  • Advance drug discovery programs by interacting with other biologists, chemists and external collaborators.
  • Contribute effectively to patent, report and scientific publication writing.
  • May have the opportunity to manage one or more Research Associates.

Job Requirements:

  • PhD. in Biology/Molecular Biology or equivalent.
  • Minimum of 5-8 years relevant experience in the biotechnology industry strongly preferred.
  • Broad practical experience and knowledge of integrin signaling, pathways leading to cell (epithelial, fibroblast, myofibroblast) activation in fibrotic processes and/or oncology.
  • High level of creativity and productivity with strong problem solving skills.
  • Excellent scientific expertise in fibrosis and/or inflammation conversant with the current literature.
  • Ability to champion the biology efforts into new directions to achieve project milestones.
  • Strong evidence of conceptual thinking, active follow through and vigorous scientific curiosity.
  • Proven ability to work well with others in a dynamic and highly collaborative environment.
  • Exceptional interpersonal, verbal and written communication skills

 


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Scientist Vaccine Immunologist

Date Posted:
4/25/2017

Neon Therapeutics

MA

  • Position Summary

    Neon is seeking a highly-motivated Scientist to join Neon’s Biochemistry group. The candidate will work within the biochemistry group and in close collaboration other groups at Neon on a program that aims to design novel personalized neo-antigen based cancer vaccines. He/she will work independtly as well as part of a multi-disciplinary research team to develop different vaccine technologies.

     

    Job responsibilities include:

    • Expression of recombinant proteins in bacterial cells and protein purification by affinity, ion-exchange, size-exclusion chromatography and protein characterization.
    • Design and molecular cloning of protein constructs and protein engineering.
    • Perform biochemical assays to study protein interactions
    • Participate in the design, development and implementation of cell-based assays.
    • Improvement of current processes and implementation of new technologies.
    • Analysis and presentation of results to larger scientific groups.
    • Work productively in a team environment and independently and deliver against timelines.

     

    Experience and essential skills:

    • PhD in Biochemistry or related biological Science with 0 to 5 years of post-graduate working experience in academia or industry
    • Expert in protein biochemistry and proficiency in various protein purification techniques such as affinity, ion exchange, gel filtration.
    • Strong experience in protein characterization and bioanalytical techniques such as SDS-PAGE, Western blot, ELISA, SEC required.
    • Deep understanding of molecular biology and hands-on-experience in molecular cloning (e.g. Gibson assembly)
    • Knowledge of immunology and dendritic cell biology, and experience in cell culture work.
    • Demonstrated experience in complex problem solving and strong publication record.
    • Excellent organizational, communication skills and a pro-active mentality.
    • Excellent attention to detail.
    • Demonstrated experience functioning within a multi-disciplinary team and utilizing cross-functional information, such as immunology and vaccine development, to optimize the biochemical work flow;
    • Demonstrated experience working with contract research organizations and academic collaborators

     

    Optional Skills:

    Experience with protein bioanalytical methods like SEC-MALS and DLS are beneficial.

     


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Scientist Biochemistry

Date Posted:
4/25/2017

Neon Therapeuitcs

MA

  • Position Summary

    Neon is seeking a highly-motivated Scientist to join Neon’s Biochemistry group. The candidate will work within the biochemistry group and in close collaboration other groups at Neon on a program that aims to design novel personalized neo-antigen based cancer vaccines. He/she will work independtly as well as part of a multi-disciplinary research team to develop different vaccine technologies.

     

    Job responsibilities include:

    • Expression of recombinant proteins in bacterial cells and protein purification by affinity, ion-exchange, size-exclusion chromatography and protein characterization.
    • Design and molecular cloning of protein constructs and protein engineering.
    • Perform biochemical assays to study protein interactions
    • Participate in the design, development and implementation of cell-based assays.
    • Improvement of current processes and implementation of new technologies.
    • Analysis and presentation of results to larger scientific groups.
    • Work productively in a team environment and independently and deliver against timelines.

     

    Experience and essential skills:

    • PhD in Biochemistry or related biological Science with 0 to 5 years of post-graduate working experience in academia or industry
    • Expert in protein biochemistry and proficiency in various protein purification techniques such as affinity, ion exchange, gel filtration.
    • Strong experience in protein characterization and bioanalytical techniques such as SDS-PAGE, Western blot, ELISA, SEC required.
    • Deep understanding of molecular biology and hands-on-experience in molecular cloning (e.g. Gibson assembly)
    • Knowledge of immunology and dendritic cell biology, and experience in cell culture work.
    • Demonstrated experience in complex problem solving and strong publication record.
    • Excellent organizational, communication skills and a pro-active mentality.
    • Excellent attention to detail.
    • Demonstrated experience functioning within a multi-disciplinary team and utilizing cross-functional information, such as immunology and vaccine development, to optimize the biochemical work flow;
    • Demonstrated experience working with contract research organizations and academic collaborators

     

    Optional Skills:

    Experience with protein bioanalytical methods like SEC-MALS and DLS are beneficial.

     


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Scientist/Senior Scientist Pharmacology

Date Posted:
4/25/2017

Constellation

MA

Constellation Pharmaceuticals is a pioneering epigenetics company, focused on the discovery and development of novel, small molecules targeting chromatin regulatory proteins in tumor and immune cells for therapeutic applications in oncology. Our unique discovery platform integrates our understanding of chromatin-regulatory mechanisms with cancer and immune pathways to optimize our drug discovery activities and fully enable the clinical translation of our programs.

We are seeking an experienced, accomplished and resourceful scientist with a successful track record in in vivoand in vitro pharmacology to join our research group. The role involves working closely with the project team leaders to design, execute and evaluate PK-PD and efficacy studies for lead compounds. The ideal candidate will have significant small molecule drug discovery experience in rodent pharmacology as demonstrated by scientific publications/ patents/ high impact projects. The successful applicant will be independent, organized, detail oriented, flexible, and will enjoy working in a dynamic, fast paced team environment.

Key Responsibilities:

  • Independently design, execute and interpret in vivo pharmacology experiments to characterize small molecule based drug pharmacology and mechanism of action to support projects from early discovery to clinical development
  • Manage relationship with external CROs to execute experiments
  • Serve as the pharmacology lead/expert on the project teams and effectively work with others in a highly collaborative, matrixed research environment teams
  • Formulate data-driven decisions by designing and executing experiments that support critical decision making for the program teams
  • Analyze, interpret and communicate data to project teams and senior R&D leadership
  • Additional responsibilities may include, collaborating with biology scientists to establish target engagement assays to support drug discovery
  • Maintain active and timely records of experiments in appropriate databases and e-notebooks and contribute to active dissemination of data
  • Be up-to-date on recent scientific literature and contribute to the understanding of our target space.
  • Attend and present at scientific meetings

Qualifications and Required Experience:

  • Ph.D. in Pharmacology or a related biology discipline, postdoctoral experience and 3-5 years of industry experience.
  • Experience with in vivo model selection, design of PK/PD/ efficacy and drug combination studies.
  • Experience with small molecule based- drug discovery is required.
  • Experience working with CROs and KOLs to conduct in vivo pharmacology experiments is required.
  • Extensive laboratory experience developing and conducting in vitro and in vivo assays.
  • Prior experience with small animal pharmacology (dosing, bleeding, blood/tissue analysis).
  • Proven record of scientific achievements demonstrated by publications and presentations.
  • Excellent oral and written communication skills.
  • Expertise in the area of immuno-oncology and familiarity with syngeneic models a plus.
  • Experience with use of PK and PK/PD modeling and simulation software such as WinNonlin or NONMEM a plus.

 


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Scientist Cancer Immunology

Date Posted:
4/22/2017

Dragonfly Thearpeutics

MA

About Dragonfly
Founded in 2015 by Dr. Tyler Jacks, head of the Koch Institute at MIT, Dr. David Raulet, one of the world's leading experts in Natural Killer (NK) cell biology, and Bill Haney, a longtime tech entrepreneur and investor, Dragonfly Therapeutics develops novel first-in-class therapeutics targeted at Natural Killer cells and other cells of the innate immune system. Our therapies are designed to counterbalance immune suppressive factors present in the tumor microenvironment and mobilize anti-cancer immune responses, and are expected to be potent as single agents as well as in treatment combinations with existing cancer immunotherapies – such as T cell treatments.  Dragonfly’s Scientific Advisory Board and founders are major figures in cancer biology and immunology, and launched Dragonfly to harness the power of the immune system to provide breakthrough cancer treatments for patients. 
 
Scientist, Cancer Immunology
Dragonfly Therapeutics seeks an experienced and motivated Scientist to support the development of new cancer immunotherapies. The Scientist will work with Dragonfly’s team to discover and develop novel biologic drugs that stimulate immune responses against solid and hematologic cancers.
 
Responsibilities:
·         Play a key role in the development of new biologic drugs for cancer immunotherapy
·         Design and execute in vivo pharmacology studies in mice: drug dosing, tumor growth monitoring, blood/TIL/lymphoid tissue isolation and analysis, necropsy, pharmacokinetics, toxicity assessment
·         Purify immune cell subsets, particularly NK cells, from human and mouse blood/tissue samples, and maintain primary cell cultures
·         Develop and perform of cell- and ELISA-based immune assays, immunophenotyping, and IHC/IF
·         Troubleshoot assays and establish standard operating procedures as needed
·         Provide scientific expertise and train/direct others in research techniques
·         Interface and manage external collaborators and CROs as needed
·         Work collaboratively with the Dragonfly team
 
Qualifications:
·         Ph.D. degree in immunology, cancer biology, or relevant field
·         4+ years of relevant research experience, industry experience preferred
·         Strong understanding of immunology and cancer biology
·         Expertise in handling primary T cells or NK/ILC cells from mice and patients/human donors
·         Experience with syngeneic and transplanted tumor models in mice
·         Mastery of cell-based immune assays, flow cytometry, and in vivo techniques for mouse studies
·         Ability to design, effectively communicate, and implement research plans efficiently
·         Excellent written and verbal communication skills and time management skills
·         Ability to work within a team, coordinating with other scientists and leading Research Associates
·         Self-motivated, conscientious, and enthusiastic about curing cancer

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Scientist Target Discovery Group

Date Posted:
4/22/2017

Dana Farber Cancer Center

MA

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

The Belfer Center for Applied Cancer Science is an integrative research center within Dana-Farber Cancer Institute, Harvard Medical School. Our mission is to enhance and accelerate oncology drug discovery & development through bridging of academia, industry and the clinic. We apply industrial capabilities to cutting edge academic/clinical science. We partner with industry in drug discovery/development & work with industrial partners to delineate the clinical path of novel therapies for cancer patients. This integrated goal-oriented organization represents a new academic construct that provides an unprecedented opportunity to change the way anti-cancer therapeutics are discovered and developed

 


									
Requirements

Job Summary

The Belfer Center offers a novel opportunity to participate in the rapidly evolving field of cancer therapeutics for treatment of cancer patients. We seek a highly motivated, collaborative, and scientifically rigorous cancer biologist to join our Center. Working with leading academic clinicians and scientists at a premier cancer institute the successful candidate will do ground breaking work elucidating and developing novel targets for drug discovery. This individual will work with Belfer and Dana Farber scientists to identify next generation cancer targets in several cell autonomous pathways regulating cancer cell growth and in emerging immuno-oncology pathways that enable clinical development strategies for single agent or combination immunotherapies for cancer.

Job Responsibilities

  • Participate in multi-laboratory collaborations to characterize novel drug targets and therapeutic approaches for cancer drug development.
  • Responsible for validating novel oncology targets and biomarkers
  • Delineate the clinical path for novel small molecule inhibitors
  • Responsible for pre-specified deliverables to external industry partners within specified timelines
  • Mentor and manage a group of scientists to deliver innovative results
 

Job Qualifications:

 

  • A Ph.D. in molecular biology, cancer biology, or biological sciences
  • 2-3 years post-doctoral experience
  • Experience in CRISPR genome editing is desired
  • Experience and expertise in flow cytometry is preferred

 

  • Demonstrated scientific excellence & scientific rigor
  • Independent, self-motivated and innovative
  • Strong management and organizational skills
  • Excellent written and oral communication skills
  • Outstanding interpersonal skills
  • Ability to work productively & constructively in a team environment
  • Ability to excel in a goal-oriented, multifaceted and fast-moving team environment
  • Industry experience is a plus

 

 

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.

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Technical Scientific Writer

Date Posted:
4/22/2017

Foundation Medical

MA

Foundation Medicine is a molecular information company focused on fundamentally changing the way in which patients with cancer are treated. Our products provide more than information. They offer hope to patients, their families and friends, their physicians and caregivers.

 

We've seen the difference that our technology can make in the lives of patients, but there is still enormous potential to help even more people. In our drive to help transform the way in which patients with cancer are treated, we strive to improve every life we touch through our dedication to innovation, our commitment to people, and our passion for performance.

 

What makes Foundation Medicine so special?

The cancer treatment paradigm is evolving rapidly and we believe there is now widespread recognition that cancer is a disease of the genome, rather than a disease defined solely by its specific anatomical location in the body. Today, physicians increasingly use precision medicines to target cancers based on the specific genomic alterations driving their growth, but most currently available molecular diagnostic tests only reveal a few of the possible alterations. Foundation Medicine provides truly comprehensive molecular information products that can assess the broadest range of relevant genomic alterations from a patient's tumor and distill this complex molecular information into a concise and actionable format that reveals more treatment options for physicians and their patients.

 

We've seen the difference that our technology can make in the lives of patients, but there is still enormous potential to help even more people. In our drive to help transform the way in which patients with cancer are treated, we strive to improve every life we touch through our dedication to innovation, our commitment to people, and our passion for performance.


									
Requirements

Foundation Medicine is seeking a Scientific and Technical Writer, Regulatory Affairs. This position will assist with Regulatory Affairs activities by writing and editing technical documentation to be included in submissions to the FDA and other regulatory authorities, including the EU. This role will have the unique opportunity to contribute to the development of regulatory submissions in the rapidly growing field of diagnostic next generation sequencing as well as to gain substantial exposure to the scientific and technical aspects of cutting edge technology. The Scientific and Technical Writer will work closely with both Regulatory Affairs, R&D scientists, biostatisticians and software engineers to produce high quality deliverables for regulatory submission. This role will be critical in ensuring that highly technical documentation is concise and understandable to readers that have a relevant scientific background but may not be well versed in the specifics of our technology.

 

Your Impact

As a member of the Regulatory team, you will:

  • Review and edit technical documentation including:
    • Validation Protocols and Reports
    • Software documentation
  • Write and assist in the preparation of FDA submissions including Pre-submission documents, IDE applications, 510(k) applications, premarket notifications/applications and post-market reporting
  • Assist in publishing submissions
 

 

Your Expertise

  • Must have:
    • Strong scientific background in molecular biology
    • Superior technical and scientific writing skills
    • Must be detail oriented with excellent prioritization and organizational skills
    • Ability to deliver results on schedule in a fast-paced, dynamic environment
    • Ability to distill and simplify complex ideas
  • Highly desired:
    • Scientific background in oncology
    • Experience with molecular biology assay validation
    • Experience with regulatory submissions (PMA, IDE, 510(k)
    • PhD preferred with at least 1 years of experience in the pharmaceutical, biotechnology, medical device, or diagnostic industries, or MS with 2+ years of experience as a technical writer.
  • Driven. You will be focused on the achievement of major alliance goals.
  • Solutions focused. Willing to bring creative problem-solving skills to challenges along the way.
  • Scientifically-oriented. You will enjoy learning and being involved in the content of our collaboration activities, and able to converse fluidly with internal and external team members on project goals and activities.
  • Intuitive. You will have a demonstrated ability to work in the “gray zone” and anticipate challenges before they arise.
  • Process-oriented, yet flexible. You will appreciate and be able to create and drive process, and at the same time recognize when rules are meant to be bent.
  • Ability to communicate clearly and concisely with all stakeholders.
  • Independent. You will be able to self-organize and operate effectively without significant day-to-day oversight, while staying tightly connected to key leaders and teams across the collaborations.

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Scientist Computational Biology

Date Posted:
4/22/2017

Commonwealth Sciences

MA

  • Analyze gene editing experiments using next generation sequencing
  • Contribute to CRISPR/ gRNA design for single/ multiple targets
Requirements
  • Ph.D. degree in related discipline
  • NGS experience a must
  • Strong knowledge of UNIX
  • R/ Python statistical language a plus
 

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Postdoc Immunology

Date Posted:
4/22/2017

Syros Pharma

MA

Syros Pharmaceuticals is seeking a dynamic Immunologist to join a team of highly motivated scientists that are using recent fundamental insights into transcriptional regulation to discover and develop novel medicines targeting gene control in cancer, tumor immunology and autoimmunity.

We are an innovative drug discovery company founded in 2012 by leading scientists from the Whitehead Institute and the Dana Farber Cancer Institute with support from top venture firms and a world class Scientific Advisory Board. Combining new insights into gene enhancer function with information from genome-wide profiling, we are pursuing new targets and chemical approaches in an effort to unlock the process of gene control for drug discovery for oncology and autoimmunity.

The Postdoctoral Fellow will participate with project teams in shaping the Autoimmunity research strategy. The motivated individual will be responsible for cell assay development for new target identification and validation for Syros’ discovery and development teams. The successful candidate will have broad subject expertise including Immunology, Cell and Molecular Biology. Expertise in immunological assays including multi-parameter FACS analysis of human and mouse primary cells, cell purification, ELISA, and cell differentiation/proliferation is important. Experience with the culture and activation of primary T and B cells is required. In addition, the candidate should have knowledge in design, execution, and interpretation of  in-vivo studies for validation of potential drug targets in the autoimmunity area. Working knowledge of basic molecular biology techniques such as PCR, cloning, nucleic acid purification and gene transfer technologies (transfection, retroviral transduction) is a plus. Additionally, basic familiarity with next generation sequencing technologies and bioinformatics is desirable.

Responsibilities:

-Provide hands on scientific capabilities in the areas of autoimmunity to both preclinical discovery project and development project teams.

-Deliver critical project data internally and through a network of external study providers. Support Autoimmunity team by providing data to be used in collaborating with leading KOLs.

-Participate in biological selection and in vitro validation of novel drug targets

-Work with team to develop assays to validate drug targets through in vivo proof of concept studies which will include responsibility for study design, monitoring at CRO, data analysis, and interpretation of in vivo study reports.

-Participate in discussions with project team biologists to define the appropriate dose & schedule for novel drug candidates in the chosen in vivo model

- Work with project teams, external collaborators, and CROs, on existing programs and new drug target programs  in the area of autoimmunity

 - Must be flexible and able to contribute to an evolving portfolio of projects spanning early discovery through preclinical stage. 

-Clear communication and presentation skills are a requirement

Requirements

Requirements:

Ph.D. in Immunology or Cell/Molecular Biology or equivalent area with a proven track record of publications in peer reviewed journals.

Must be authorized to work in U.S.

 

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Scientist Structural Biology Biochemistry

Date Posted:
4/22/2017

Fog Pharma

MA

Description

FogPharma is developing breakthrough treatments for patients in serious need through the creation of a powerful new class of medicines, cell-penetrating miniproteins, that target human disease drivers currently considered “undruggable.”  FogPharma is located in Cambridge, MA. 

Job Summary

Our team is seeking a structural biochemist to elucidate the binding and inhibitory mechanisms of novel compounds that target undruggable proteins.

Job Responsibilities 

  • Expression and purification of recombinant target proteins
  • Crystallization, structure determination, and structural analysis of protein-ligand complexes
  • Biochemical characterization of target-ligand binding, with development of new assays as needed
Requirements
  • PhD in biochemistry, chemistry, structural biology, or related field
  • 3+ years relevant post-doctoral or industry experience
  • Extensive experience with protein expression, purification, and characterization; strong working knowledge of Akta purification instruments
  • Extensive experience with all aspects of protein crystallography, including crystallization robotics, data collection, and structure determination
  • Broad experience with in vitro biochemical methods, particularly ligand-binding assays (e.g. pulldowns, SPR/Biacore, FP, FRET, ITC, etc).
  • Deep understanding of biochemistry concepts and literature
  • Aptitude with structural analysis and communication/visualization of findings to team
  • Independence, initiative, focus, willingness to take on responsibility and continually pursue self-improvement
  • Ability to work in a team, communicate, and give/receive constructive feedback
  • High attention to detail, excellent organizational and documentation skills
 

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Senior Scientist Cellular Bioassay

Date Posted:
4/22/2017

TORQUE

MA

Senior Scientist – Cellular Bioassay - TORQUE

TORQUE is focused on developing a whole new category of cell therapies for cancer. The goal is to develop a next generation of immunotherapies to address otherwise intractable cancers – particularly solid tumors. We are a small - yet experienced and well-funded - startup in Kendall Sq, Cambridge.

TORQUE is seeking an independent and highly motivated scientist that will focus on developing functional immune cell assays. The ideal candidate will have industry experience, and a strong background in working with human T-cells and characterizing them by flow cytometry. Familiarity with cell-based assay development for drug potency is a must. Demonstrated examples of previous work in studying protein mechanisms of action, such as receptor binding, receptor activation, cell signaling, internalization and/or subcellular localization in cell-based assays are sought.

Requirements: Ph.D. with 3+ years of experience working in drug development, or MS with 5+ years of experience

Write to: Torque, 450 Kendall St, Cambridge, MA 02142 or email: jobs(at)torque.email

Requirements

Requirements: Ph.D. with 3+ years of experience working in drug development, or MS with 5+ years of experience


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Research Scientist Protein Biochemistry

Date Posted:
4/22/2017

Sciversify

NC

We are seeking an experienced research scientist or associate to join the founding R&D team of a Triangle-based biotechnology company which is developing an innovative clinical diagnostics platform.

In this position, you will be a key member of the company’s assay development team, led by a world-renowned investigator who is widely recognized for pivotal breakthroughs in protein engineering and fluorescent sensor development. You’ll be joining the team on the ground floor as the company drives its cutting-edge diagnostic platform through the discovery phase and into assay optimization, device development, pre-clinical testing, and commercialization. Your overall responsibilities will include:
• Developing and leading one or more collaborative, multi-disciplinary projects focused on specific fluorescent sensor-based diagnostic assays
• Establishing and reporting on project requirements, plans, and accomplishments under the direction of the company’s senior executives
• Ensuring that project milestones are consistently achieved in accordance with expectations from corporate leadership and external investors
• Providing cross-training, expertise, and assistance to other project teams to accelerate assay development and optimize related procedures

You’ll work alongside other exceptional scientists who share your passion for advancing basic research discoveries into the clinical realm. And you will gain valuable experience with the entire translational R&D life cycle of a biotechnology start-up, from both the technical and business perspectives. Your research roles will include:
• Using bioinformatics-based approaches to identify candidate proteins for fluorescent sensor-based clinical diagnostic tests
• Refining and carrying out protocols for the expression, purification, labeling, and characterization of candidate proteins
• Working across teams to develop and optimize procedures for immobilizing fluorescently responsive proteins on solid-state assay substrates
• Maintaining and providing detailed experimental data and other technical inputs to company executives for project management, monitoring, and reporting activities
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Job Requirements


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This position requires a graduate degree in a relevant scientific field (PhD preferred), at least two years of postgraduate experience, and a high degree of competency with advanced protein chemistry and engineering methodologies. The successful candidate will have expertise in protein purification, stability, and ligand binding, as well as a strong understanding of bioinformatics, sequence analysis, and molecular biology concepts. The selected individual will also have:
• Excellent verbal and written communication skills
• Rigorous attention to detail and experimental procedures
• Competency in running software and computer-based tools
• Strong ability to lead and collaborate within and across teams
• Flexibility and adaptability to rapidly changing priorities
• Multi-disciplinary mindset and a drive toward big challenges
• Commitment to advancing clinical diagnostic and care capabilities
• Willingness to go the extra mile for projects and team members

The individual selected for this position will receive a highly competitive compensation package and the opportunity to accrue company stock grants and/or options.

This is an immediate opportunity with the hiring company, and resumes will be reviewed upon submission over the next month. Qualified candidates will be selected for an in-depth interview and evaluation process to ensure that the selected individual will hit the ground running and excel in the position. As part of this process, candidates will be required to provide several professional references and to complete a writing and analysis exercise.

To be eligible for this opportunity, candidates must be legally authorized to work in the United States on a full-time basis and for any employer.

Interested individuals can apply directly at http://careers.sciversify.com.

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Scientist I/II

Date Posted:
4/22/2017

Medimmune

MD

Poisition Description:
MedImmune is the worldwide biologics research and development arm of AstraZeneca. Here, you'll have the opportunity to make a difference in people's lives every day. As one of the world's premier biotechnology companies, our mission is centered on delivering life-changing products that advance world health, and help fight and cure disease. As a Scientist I/II in Gaithersburg, MD, you'll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients' lives.
We're constantly pushing the boundaries of science to deliver life-changing medicines to patients, with a passion for discovery and a pipeline to show for it. We're pioneering innovative research and exploring novel pathways across key therapeutic areas including oncology, respiratory, inflammation and autoimmunity, cardiovascular and metabolic disease, and infection and vaccines. And we're industry-leading in immunology, protein engineering and translational science. We offer a unique and strong collaborative network as part of the AstraZeneca family, as together we explore synergies between small and large molecules.
MedImmune has a dynamic environment that fosters collaboration and innovation. We attract top minds, and we nurture and build top talent.

Responsibilities:
MedImmune is seeking a versatile molecular biologist with virology/immunology experience to explore new technologies relevant to in vivo biologics expression and/or novel pulmonary drug delivery approaches. Potential areas of interest include viral vector based biologics expression platform (e.g. AAV, Ad, RNA viruses), nucleoside-modified RNA antigen expression platforms, and tissue targeted biologics drug delivery (e.g. airway, solid organs). The candidate will be part of a growing cross functional effort to identify novel biologics expression and delivery approaches to combat respiratory disease, and is expected to be creative and innovative in their approach. Supervisory duties may be involved in the future.

Requirements:
This position will be a lab-based, hands-on research position. The appropriate candidate should have strong experience in some of the following areas: molecular cloning, viral vector engineering for gene therapy (AAV experience is plus), nucleotide synthesis and formulation for tissue targeted delivery, protein chemistry, bioconjugation, immunoassays etc.
Strong motivation, attention to detail, ability to conduct high quality research, deal with complex scientific/biologic concepts and ability solve complex problems independently is expected. Must have a proven record to effectively plan and organize work activities and prioritize task completion in a timely fashion. Excellent written, verbal and presentations skills is required
This position will require innovation and an innovative researcher with solid technical skills. The candidate should have demonstrated problem solving skills and versatile research abilities. Prior experience working in the collaboration or in a multidisciplinary matrix environment is desirable.

Experience:
PhD in molecular virology, cell biology, immunology or related scientific discipline with 3+ years of post-degree relevant experience

To Apply:
To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience.

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.


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Senior Scientist in Microbiology

Date Posted:
4/19/2017

Fluid Screen

MA

SENIOR SCIENTIST IN MICROBIOLOGY, MICROFLUIDICS, MICROSCOPY, BIOMEDICAL ENGINEERING

FLUID-SCREEN, INC., CAMBRIDGE, MASSACHUSETTS

Position Description:
Fluid-Screen, Inc. is an award winning Life Sciences startup based in Cambridge, MA. We are commercializing a technology developed at Yale University that can rapidly detect bacterial contamination that can help prevent infectious disease outbreaks and save lives in a variety of settings.
Fluid Screen's lab-on-a-chip system detects bacteria in water, blood and urine with the sensitivity of single bacterium in just 30 minutes, compared to a day or more for alternative technologies. The patented technology and the team have been recognized with the Grand Prize in the Create the Future NASA Design contest (#1 out of 900 entrants worldwide), a Gold Prize in Mass Challenge (top 1% of contenders), and more than ten other awards, the research has been published in Nature.
The company specializes in the development of rapid microbiology solutions for a range of industries including water testing, pharmaceutical manufacturing, and medical diagnostics.
The company is seeking an experienced Senior Scientist to join the team and lead R&D in our Cambridge lab space (LabCentral). The successful candidate will be highly independent, excited to design and execute research activities to develop and test our cutting-edge technology, and willing to expand capabilities in new fields. Do you envision yourself solving some of the world's most important problems? Do you thrive in a high growth, fast paced environment with access to state of the art lab facilities? If so, then this is the opportunity for you.

Experience:

  • Advanced Degree (PhD preferred) in microbiology or biomedical engineering, additional background in medical devices or nanotechnology a plus
  • Experience with optical and fluorescent microscopy
  • Hands-on lab experience with a broad range of methods/technologies/equipment, including: biomedical engineering or microfluidic devices
  • Track record with meticulous bench work and record keeping
  • Ability to focus on the task at hand
  • Strong ability to troubleshoot and problem-solve experiments
  • Experience with BL2 lab practices
  • Proven ability to design and oversee all phases of experiments
  • Comfort handling sensitive materials

Qualities:

  • Independent, self-starter that works well under minimal supervision. You will be responsible for contributing to R&D functions that play a key role on upcoming pilot studies
  • Strong communication. This is a must. It is essential for our team to communicate effectively to deliver complete results
  • Passion for bench work
  • Ambitious with proven leadership track record. This is a high growth opportunity with the potential to help shape the growth of our company
  • Comfortable in fast-paced environments. Must be able to meet deadlines
  • Impact Driven. Fluid-Screen was developed to make a difference in the world
  • Flexible. This is an early stage startup-processes and responsibilities are constantly changing
  • Adaptable. Always willing to help get the job done-no task too big or too small
  • Creative. Your unique thought processes will become key to the success of the company

Culture:
Fluid-Screen is a multi-disciplinary, tight-knit group looking to add another enthusiastic member to our team. We are passionate about our work as we truly believe it will make a difference in the world. This includes taking on responsibilities that may be completely new to you-which should be an exciting opportunity for personal growth!
Interested?

To Apply:
Please include a CV and desired compensation and email: jobs@fluid-screen.com
subject: Senior Scientist (NIH)


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Postdoctoral Affairs Specialist

Date Posted:
4/19/2017

Van Andel Research Institute

MI

POSTDOCTORAL AFFAIRS SPECIALIST

VAN ANDEL RESEARCH INSTITUTE, GRAND RAPIDS, MICHIGAN

Position Description:
Van Andel Research Institute (VARI) is a leading independent biomedical research facility and is dedicated to determining the epigenetic, genetic, molecular and cellular origins of cancer, Parkinson's and other diseases, and translating those findings into effective therapies. The Institute is home to more than 330 scientists and support staff that work in on-site laboratories and in collaborative partnerships that span the globe.
VARI strives to create an environment that stimulates creativity and nurtures professionalism and our Office of Postdoctoral Affairs (OPA) is committed to maintaining the highest standards of postdoctoral training and to provide a program that prepares our postdocs for the next step in their career.

To ensure we are providing our postdoc's the best in research training, we are seeking to hire a Postdoctoral Affairs Specialist to join our OPA team.
As a Postdoctoral Affairs Specialist, your first and foremost responsibility will be to administer and assist in the development of programs, workshops, and professional development opportunities aimed at enhancing the postdoctoral training at VARI.
We also understand winning a competitive fellowship or grant is a mark of distinction in a postdoc's career progression and we encourage our postdoctoral fellows to apply for their own fellowship support during their training at VARI. As the Postdoctoral Affairs Specialist you will also play a role in identifying appropriate funding opportunities and training and writing high quality grant/foundation proposals. These applications will be from government (NIH, NSF, DoD, DTRA, etc.), private grant making foundations, and international sources.

Responsibilities:

Professional and Career Development:

  • Assisting with the planning, developing, and implementing of educational and career training programs for our postdocs.
  • Coordinate workshops, career training events, and professional development opportunities
  • Develop and maintain postdoc resource materials and content to the Office of Postdoctoral Affairs SharePoint site.
  • Assists in the recruitment efforts of postdoctoral fellows through recruiting events, recruitment materials, and networking
  • Administer the postdoc alumni database

Grant Writing and Mentoring:

  • Reviewing literature dealing with grant funds available through government/international agencies and private foundations
  • Working closely with our postdoctoral fellows and their principal investigators on strategizing and identifying appropriate funding opportunities
  • Providing advice/mentorship on policies, guidelines, and practices of relevant funding agencies
  • Facilitating our postdocs, and at times, drafting, and editing proposals
  • Ensuring timely delivery of innovative and approvable grant submissions
  • Assisting in the development of work plans and project timelines for each grant application

Qualifications:
This job might be right for you if:

  • You are motivated and driven. You take ownership of your projects. You like learning new things and advancing your skill set. If you don't know the answer, you'll dig until you find it
  • You love taking on difficult challenges and finding the best solution whether it be tried-and-true or cutting edge
  • You enjoy collaborating and working as a team. You are passionate about building relationships and have a passion for postdoc advocacy and engagement
  • You have a well-established track record of critically contributing to the preparation and able to drive the work of multiple people towards the submission of high quality, competitive grant proposals
  • You are an outstanding writer able to communicate in a compelling and succinct form
  • You have the ability to work well under pressure and perform under tight deadlines

To join our team you need to have at least:

  • A Master's degree (Ph.D. and postdoc experience preferred) in molecular/cellular biology, biochemistry, neurobiology, or other life science.
  • Career and/or professional development training experience
  • Demonstrated ability to identify appropriate scientific funding opportunities.
  • Extensive experience and demonstrated ability to write scientific proposals, publications, reports and presentations.
  • Highly proficient with MS Office and Adobe Acrobat.
  • Ability to work independently and collaboratively with a diverse workforce.

To Apply:
Interested candidates should submit a cover letter and resume as a single combined PDF file here. In your cover letter, please outline your skills and experience in digital integration and communications, your future career goals, and how these factors fit with the position described.

This position will be open until filled. If you have any difficulty uploading your application or any questions, please email Eric Miller at eric.miller@vai.org.

VAI is actively striving to diversify its workforce and strongly encourages qualified individuals from underrepresented groups to apply. Van Andel Institute is an EEO and Affirmative Action Employer.


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Science Officer

Date Posted:
4/19/2017

Ripple Effect Communicatiom

MD

Job description

Job Summary

 

Where Creating the Best Hope for a Healthier Future Begins...

 

Position Summary

 

Plans, supervises, and directs research, investigation, or other technical operations. Provides technical expertise to facilitate the design, implementation, and analysis of procedures, techniques, and results which enables investigators to conduct research projects.

 

Position Key Accountabilities

 

Additional Summary Specific to Job

 

  • Determines feasibility of possible projects to ensure results will have a significant impact. Determines project feasibility in terms of staff, time, and resources.
  • Plans and performs quantitative and qualitative research procedures in various areas of biology, chemistry, physics, and other biomedical, dental, or related scientific areas. Identifies the problem through contact with other researchers, practicing physicians, or literature searches. Formulates a problem or project to research. Designs procedures to solve the problem.
  • Conducts experiments using advanced equipment and applying complex techniques. Procedures may include tissue culture, protein purification, enzyme purification, enzyme assays, membrane protein purification, monoclonal antibody analysis, cytogenic analysis, gel electrophoresis, immunoelectrophoresis, immunofluorescent method, radioimmunoassays, biometry, biofeedback, neurotransmitter analysis, biospectrometry, microtomy, liquid, gas and thin layer chromatography, microspectrophotometry, tissue processing, tissue staining, behavioral testing, anesthetic dosage, neurohistochemistry, animal surgery, immunochemistry, gel electrophoresis, deoxyribonucleic acid (DNA) testing, electron microscopy, and biophysical assays and measurements.
  • Designs experimental procedures, which may involve examining new techniques, that may improve existing analysis and provide additional capabilities.
  • Evaluates the data from the analysis.
  • Presents results in a written paper for publication, in a presentation at a meeting, or through personal contact with faculty members and other researchers.
  • Maintains lab equipment, assists in necessary repairs, and promotes a safe laboratory environment. Ensures direct reports follow safety procedures and attends basic safety training courses.
  • Provides work direction and guidance to personnel within department. May lead projects and activities.
  • Performs other duties as assigned.

     

Organizational Requirements

 

Minimum Education

 

Doctorate Degree.

 

Minimum Experience

 

Two (2) years of experience in a related research environment and have verifiable publications within the field of the research project.

 

Departmental Requirements/Preferences


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Research Scientist

Date Posted:
4/19/2017

University of Texas

TX

Job description

Job Summary

 

Where Creating the Best Hope for a Healthier Future Begins...

 

Position Summary

 

Plans, supervises, and directs research, investigation, or other technical operations. Provides technical expertise to facilitate the design, implementation, and analysis of procedures, techniques, and results which enables investigators to conduct research projects.

 

Position Key Accountabilities

 

Additional Summary Specific to Job

 

  • Determines feasibility of possible projects to ensure results will have a significant impact. Determines project feasibility in terms of staff, time, and resources.
  • Plans and performs quantitative and qualitative research procedures in various areas of biology, chemistry, physics, and other biomedical, dental, or related scientific areas. Identifies the problem through contact with other researchers, practicing physicians, or literature searches. Formulates a problem or project to research. Designs procedures to solve the problem.
  • Conducts experiments using advanced equipment and applying complex techniques. Procedures may include tissue culture, protein purification, enzyme purification, enzyme assays, membrane protein purification, monoclonal antibody analysis, cytogenic analysis, gel electrophoresis, immunoelectrophoresis, immunofluorescent method, radioimmunoassays, biometry, biofeedback, neurotransmitter analysis, biospectrometry, microtomy, liquid, gas and thin layer chromatography, microspectrophotometry, tissue processing, tissue staining, behavioral testing, anesthetic dosage, neurohistochemistry, animal surgery, immunochemistry, gel electrophoresis, deoxyribonucleic acid (DNA) testing, electron microscopy, and biophysical assays and measurements.
  • Designs experimental procedures, which may involve examining new techniques, that may improve existing analysis and provide additional capabilities.
  • Evaluates the data from the analysis.
  • Presents results in a written paper for publication, in a presentation at a meeting, or through personal contact with faculty members and other researchers.
  • Maintains lab equipment, assists in necessary repairs, and promotes a safe laboratory environment. Ensures direct reports follow safety procedures and attends basic safety training courses.
  • Provides work direction and guidance to personnel within department. May lead projects and activities.
  • Performs other duties as assigned.

     

Organizational Requirements

 

Minimum Education

 

Doctorate Degree.

 

Minimum Experience

 

Two (2) years of experience in a related research environment and have verifiable publications within the field of the research project.

 

Departmental Requirements/Preferences


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Scientist Cellular Immunology

Date Posted:
4/19/2017

Bluebird Bio

MA

Join bluebird bio’s enthusiastic and collaborative Cellular Immunotherapy team by contributing to the overall success of our novel gene-based immunotherapy approach. This new Scientist will join our group to design, develop and evaluate novel cellular immunotherapy approaches for clinical applications.

 

 

 

About the job:

  • Work in a team focused on preclinical development of cellular therapeutics
  • Design and develop immunological assays to characterize genetically engineered primary T cells
  • Potential to lead a team of 1-2 research associates
  • Coordinate research projects evaluating strategies to improve efficacy of cellular therapeutics
  • Prepare all technical reports needed in support of an exploratory project moving to process development
  • Exercise independent judgment in development of new methods, techniques and evaluation criteria
  • Effectively interface with other scientific groups in bluebird bio to facilitate the success of projects
  •  

About you:

  • PhD in molecular or cellular immunology
  • 2+ years’ experience beyond PhD as a post-doc in immunology or tumor biology
  • Applied experience in T cell or other immunotherapies
  • Ability to independently design, execute, interpret and communicate experimental results
  • Experience with innovative assay development to assess novel biology
  • Expertise in mammalian cell culture, with specific experience isolating and propagating in vitro culture of human/mouse T lymphocytes
  • Experienced with flow cytometry of primary human cells – cell sorting experience a plus
  • Experienced with immunological assays to assess T cell function
  • Expertise in signaling, innate immunity and cytokine function preferred
  • Expertise in gene editing a plus
  • Experience in working in animal models of adoptive immunotherapy for autoimmune disease or Oncology
  • Proven ability to effectively organize experiments to prosecute research projects studying T cell therapeutics
  • Proven ability to effectively plan and organize work activities and prioritize task completion to meet schedules and deadlines
  • Ability to work as part of a team, collaborating with members of other functional groups
  • Understanding of safe lab practices and BSL requirements
  • Excellent computer skills and experience with Microsoft Excel. Prism, sequence analysis, Flow cytometry data analysis software experience essential
  • “do-what-it-takes” attitude
  • Independently motivated, detail oriented and good problem solving ability
  • Excellent organizational skills, sufficient to multi-task in an extremely fast-paced environment with changing priorities
  • Be ready to embrace the principles of the bluebird bio culture: b colorful, b cooperative, and b yourself

 

Seniority Level

Mid-Senior level

Industry

  • Biotechnology

Employment Type

Full-time

Job Functions

  • Research
  • Science

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Postdoc

Date Posted:
4/19/2017

Cedars Sinai

CA

Job description

Summary Of Essential Job Duties

 

Working independently but in close cooperation and in consultation with the Principal Investigator and other Research Scientists, the Research Fellow candidate will perform routine and complex laboratory procedures throughout the training period. May develop, adapt, and implement new research techniques and protocols. Analyzes and interprets data. May assist in preparation of grant proposals. Participates in publications and presentations as author or co-author. Not responsible for generating grant funds, but strongly encourage to apply for postdoctoral fellowship awards.

 

  • Writes manuscript drafts and presentations as author or co-author.
  • Designs and performs experiments. Will keep appropriate and detailed experimental records/documentation. Analyze results and presents to supervisor.
  • May develop, adapt, and implement new research techniques and protocols, particularly in the area of cancer micro-environment interaction.
  • Analyzes, interprets, summarizes and compiles data for publications.
  • Be able to perform tissue recombination orthotopic xenografting of prostate cancer models.
  • Be able to independantly analyze data and determine the next experimental steps to address a defined hypothesis
  • Be facile with the current literature in tumor biology particularly signal transduction and information dealing with paracrine causes of tumor prgoression

     

Educational Requirements

 

Doctorate (MD, PhD, VMD, or DDS) in area directly related to field of biochemistry, cell biology, or cancer biology. Must have experience in principles and

 

practice of clinical research.

 

Experience

 

Works independently on research projects designed by a mentor (typically the PI) within area of specialization (Breast Medical Oncology). Must have past clinical experience. Must be familiar with clinical research and scientific writing.

 

EEO / AA / F / M / Veteran / Disabled

 

Cedars-Sinai will consider for employment qualified applicants with criminal histories, in accordance with the Los Angeles Fair Chance Initiative for Hiring.

 

Business Entity: CSMC - Cedars-Sinai Medical Center

Seniority Level

Not Applicable

Industry

  • Hospital & Health Care
  • Information Technology and Services
  • Research

Employment Type

Full-time

Job Functions

  • Research
  • Analyst
  • Information Technology

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Sr. Scientist Pain& Symptomatics

Date Posted:
4/19/2017

Merck

PA

Job description

Sr. Scientist, Pain & Symptomatics-BIO004745

 

Description

 

Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. Today, we are building a new kind of healthcare company – one that is ready to help create a healthier future for all of us.

 

Our ability to excel depends on the integrity, knowledge, imagination, skill, diversity and teamwork of an individual like you. To this end, we strive to create an environment of mutual respect, encouragement and teamwork. As part of our global team, you’ll have the opportunity to collaborate with talented and dedicated colleagues while developing and expanding your career.

 

By joining the Neuroscience department at Merck, you will engage in exciting drug discovery research targeting the symptomatic treatment of nervous system disorders including pain, Parkinson’s disease, Alzheimer’s disease, and schizophrenia. We are looking for a technically skilled in vitro scientist, that is motivated to work as part of a high profile team to apply advanced cell biology and electrophysiology techniques to identify, validate, and progress innovative novel drug targets. You will work independently, but will be expected to proactively collaborate with colleagues across disciplines.

 

Primary responsibilities include the design and implementation of in vitro experiments for target identification and mechanism of action studies including establishing in vitro cell-based model systems and performing functional/biochemical cell-based assays to support established discovery programs. The position will also require the ability to study the scientific literature, develop new technical expertise, and be an active participant in scientific dialogue in project meetings and internal/external scientific meetings.

 

Responsibilities Include

 

  • Primary role is to design, execute, interpret and report in vitro experiments.
  • Develop disease relevant cell based models using primary neuronal cells, cell lines, and/or native tissue and execute assays using these preparations.
  • Monitor, review and critically interpret published work to guide internal research.
  • Collaborate with members from other functional areas, including medicinal chemistry, in vivo and in vitro pharmacology and translational sciences.
  • Communicate data clearly and concisely.
  • Interface with external academic, biotechnology, and contract research organizations

     

Education

 

Qualifications

 

  • A Bachelor's degree in Biological or Physical Science with a minimum 7 years of pharmaceutical or biotech industry or academia experience, preferably in neuroscience, OR a Master’s degree in Biological or Physical Science with a minimum 4 years of pharmaceutical or biotech industry or academia experience, OR a Doctoral degree in Biological or Physical Science with a minimum of 1 year of pharmaceutical or biotech industry experience.

     

Required

 

  • Extensive experience with electrophysiology.
  • Primary neuronal cell culture experience.
  • Strong data analysis skills including a practical knowledge of statistics.
  • Demonstrated ability to thrive in a team environment.
  • Established record of innovative thinking to champion new ideas and solve problems.
  • Excellent oral and written communication skills, including preparation of study reports, presentations and ability to contribute to manuscripts for publication in peer reviewed literature.

     

Preferred

 

  • Experience with molecular biology or biochemistry.
  • Experience with calcium imaging and GPCR signaling.
  • Stable cell line generation.
  • Experience developing assays for high throughput screening.
  • Background in transgenic and experimental models of pain, psychiatric, or neurodegenerative diseases.
  • Experience with multiple therapeutic modalities (small molecule, antibody, peptide).
  • Familiarity with human genetics and genetic analysis.

     

Merck is an equal opportunity employer, Minority/Female/Disability/Veteran – proudly embracing diversity in all of its manifestations.

 

Job: Biology-Discovery

 

Job Title:Sr. Scientist, Biology-Discovery

 

Primary Location: NA-US-PA-West Point

 

Employee Status: Regular

 

Travel: Yes, 5 % of the Time

 

Number of Openings: 1

 

Hazardous Materials: Hepatitis ,TB Blood Test

 

Company Trade Name:Merck

Seniority Level

Associate

Industry

  • Staffing and Recruiting

Employment Type

Full-time

Job Functions

  • Research
  • Analyst
  • Information Technology

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Scientist.

Date Posted:
4/19/2017

Pfizer

IL

Job description

 

 

About Pfizer

 

A career at Pfizer offers opportunity, ownership and impact. All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.

 

 

Role Description

 

The scientist will be responsible for supporting clinical release and stability testing for the biologics program within a GMP laboratory. Their focus will be the optimization, qualification, validation, performance and transfer of analytical methods. The scientist will execute these tasks within a matrixed team environment that includes but is not limited to other groups within the Biosimilars Pharmaceutical Sciences Department and other global Pfizer sites as well as third party laboratories and vendors.

 

 

Responsibilities

 

With moderate supervision while demonstrating significant independent ownership of key program tasks, the scientist will: * Execute release and stability testing in support of the biologics program using standard and specialized orthogonal analytical methodologies for proteins/peptides (e.g. liquid chromatography, capillary electrophoresis, SDS-PAGE, UV/Vis, fluorescence, light scattering, mass spectrometry, immunochemical and cell based assays, biophysical characterization techniques) within a GXP laboratory. * Independently design and execute experiments and draw appropriate conclusions from experimental data. * Independently author high-quality technical reports and protocols. * Qualify and/or validate analytical methods to support clinical product testing. * Transfer analytical methods to and from the Biosimilars Pharmaceutical Sciences GMP testing laboratory to support in-process, lot release and stability testing of clinical and/or commercial biologics products * Collaborate with process development and/or formulation development scientists or operations personnel to plan and execute testing to support drug substance/drug product development and/or product manufacturing * Reliably meet project or initiative timelines and revise work plans as needed to address changes in project scope, priorities or timing. * Participate in functional and cross functional teams to promote the advancement of Biosimilars Pharmaceutical Sciences scientifically and in cGMP compliance.

 

 

Qualifications

 

Associates Degree and 12+ years of relevant experience OR B.S. and 6+ years of relevant experience OR M.S. and 3+ years of relevant experience OR Ph.D. and 0+ years of relevant experience. Strong background in standard and specialized methodologies for biologics products. Experience with the qualification/validation of analytical methods for biologic products. Experience in a GMP laboratory. Excellent verbal/written communication skills and the ability to work well in cross functional and/or multi-geography teams. Strong project management and organizational skills. PHYSICAL/MENTAL REQUIREMENTS Ability to perform standard laboratory work (e.g. preparing samples, solutions, performing assays, operating standard laboratory equipment, etc.) and office work (e.g. experimentation documentation, writing/reviewing/approving protocols and reports, performing data analysis, etc.). This will require sitting or standing for several hours at a time and ability to lift up to 40 pounds. NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS This position requires understanding of and adherence to cGMP and Environmental, Health and Safety guidance. Flexibility in schedule may be required for generation and collection of data for experiments with specific time constraints or for conference calls with colleagues in different time zones. Travel may be required but is expected to be less than 5%.

 

 

EEO & Employment Eligibility

 

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.


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Biological Scientist microbiology, molecular biology

Date Posted:
4/19/2017

ASTRIX

NJ

Job description

Biological Scientist

 

Clearance Level Needed: U.S. Citizenship or Green Card Holder required. Individual selected will be subject to a background investigation and must meet eligibility requirements for access to sensitive information.

 

POSITION DESCRIPTION:

  • Performing non-research molecular testing to rapidly identify and characterize potential pathogenic bacterial and viral threat agents.
  • Ensures incoming biological samples are processed and triaged maintaining chain of custody.
  • Performs and interprets a variety of specialized tests and strains, detection, and identification of pathogenic microorganisms.
  • Prepares written and oral reports, answer questions, troubleshoot and make recommendations to the supervisor for inclusion in comprehensive reports on test findings.
  • Maintains and operates equipment including performing calibrations, adjustments, and to operate equipment and instruments properly and in a safe manner.
  • Participates in cross training related to bioterrorism and other public health emergencies.
  • Responsible for maintaining knowledge and skills related to position and program.
  • Expected to properly handle, store, and dispose various biological materials in accordance with safety regulations.
  • Individual must be available 24/7/365 to respond in case of emergency.

 

REQUIRED QUALIFICATIONS:

Should have a Ph.D. or Master’s degree from an accredited university in microbiology, molecular biology or related course work in biological sciences with at least two years of laboratory bench experience, utilizing PCR, aseptic techniques and biological assays, and at least two years of experience serving as a Senior Scientist or Team Leader of a laboratory team/project. Bachelor’s degree from an accredited university requires five years of laboratory bench experience, including at least two years of experience as a Team Leader/Senior Scientist. BSL-3 experience is desirable

 

 

 

 

 

 

We are currently interviewing for this position-Qualified candidates are encourage to apply immediately!

 

Astrix Software Technology, Inc. provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, gender, national origin, age, veteran status, disability, genetic information or testing, family medical leave, sexual orientation, gender identity or expression. Astrix Software Technology, Inc. complies with federal, state and local laws governing employment nondiscrimination in all workplace locations.

 

We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.


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Scientist.

Date Posted:
4/19/2017

Proteos

MI

Job description

Scientist/Senior Scientist I: Protein Purification Group

Proteos is a high-quality contract research organization specializing in expression and purification of recombinant proteins. We are currently seeking a Scientist or Senior Scientist I to join the Protein Purification team.

Functions and Responsibilities

  • Initiates and executes customer sponsored projects independently, following standard operating procedures (SOPs)
  • Contributes to the scientific excellence of Proteos through the continuous production of high quality data
  • Performs additional non-science and/or business related job functions in support of Proteos' strategic business initiatives
  • Remains up to date on the latest biotechnology laboratory techniques and relevant literature.
  • Reports to a Scientific Director

Basic and Preferred Qualifications - Education/Experience

  • PhD or an MS plus 3 years, or a BS plus 6 years of relevant lab experience
  • Comprehensive knowledge of and demonstrated experience with scientific principles/concepts in the areas of
    • protein purification using a variety of chromatographic tools including AKTA FPLC systems
    • purification of recombinant proteins from mammalian, insect and bacterial expression systems
    • purification and analysis of antibodies or antibody fragments
    • protein analysis methods including SDS-PAGE, western blotting, HPLC-SEC, mass spectrometry, AAA, N-terminal sequencing, thermal shift assay, etc.
    • protein activity determination including plate-based enzymatic assays, binding affinity, specifically using ForteBio Octet
    • recombinant protein expression in E. coli
  • Working knowledge of expression in mammalian, insect and bacterial cell lines
  • Team player
  • Ability to work safely in a laboratory environment
  • Ability to work effectively in a fast-paced, team oriented environment
  • Excellent communication skills, both written and verbal

Benefits

  • Competitive salary
  • 401K plan with company match
  • Medical Insurance
  • Paid time off including vacation time, sick time, and 9 company holidays

Requirement

  • Successful applicants will be asked to show proof that they can legally work in the US

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Scientist

Date Posted:
4/19/2017

GeneDx

MD

Job description

This position is a Scientist I role and will be part of the R&D team responsible for developing new technologies and molecular tests for mutation analysis in our CAP/CLIA certified clinical sequencing laboratories. PhD candidates with 1-2 years of experience looking to transition from academia to industry are encouraged to apply.

 

 

Responsibilities will include:

 

  • Lead the invention, development, testing and evaluation of next generation sequencing technologies.
  • Identify bottlenecks and streamline clinical laboratory testing procedures.
  • Design high throughput and scalable next generation sequencing assays for fully automated clinical laboratories.
  • Extensive hands-on use and troubleshooting of Illumina sequencing instruments.
  • Analysis of next generation sequencing data and interpretation of results.
  • Basic shell scripting.

 

Key Skills

 

  • Fundamental understanding of molecular biology techniques and principles.
  • Ability to multitask and prioritize laboratory and data analysis taskas.
  • Strong inter personal skills and the ability to lead the successful completion of experiments.
  • Ability to correlate next generation sequencing data with changes in the laboratory procedure.

 

Requirements:

 

  • PhD in Mol Bio, Biochem, Genetics, or related field.
  • Extensive experience with molecular biology techniques, including sequencing, electrophoresis, cloning.
  • Basic understanding of bioinformatics.
  • Attention to detail and accuracy are critical
  • Ability to work independently and in a team environment.

 

Benefits:

 

  • Health,dental, vision, life insurance Long and short term disability plans

     

  • 401K retirement savings plan with a company match
  • Flexible Spending Account Tuition Assistance, Employee Discounts Paid Time Off Regular performance appraisals, merit increases
  • Work with a company of talented professionals dedicated to making GeneDx shine!
  • Supportive company structure- promoted 100 employees in the last year
  • Business casual environment, dog friendly

 

 

 

Interested candidates must submit an application via GeneDx's online portal at www.genedx.com/apply Requisition 3718BR.

 

 

 

 

 

GeneDx is a VEVRAA Federal Contractor and Equal Employment Opportunity employer.


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Data Scientist

Date Posted:
4/19/2017

Vanda Pharma

DC

Job description

Vanda is seeking a Data Scientist who will primarily be responsible for developing analytical models and providing data driven insights.

 

 

 

Roles and responsibilities include the following:

  • Improve business/scientific decisions across both a broad range of Key Performance Indicators and functions
  • Supports multiple, high impact data research and analysis projects
  • Leverage data / big data to discover patterns and solve strategic analytic business problems using both structured and unstructured data sets across many environments
  • Develop analytic capabilities that drive better outcomes for both customers and the company

Position Requirements

Successful candidates will have the following background/experience:

  • Advanced degree in computer science, mathematics, management science, engineering, operations research, statistics, or related (Master’s degree required, MD or PhD preferred)
  • 2+ years’ experience in data science, advanced analytics, and model building
  • Experience with statistical analysis methods
  • Excellent visualization experience utilizing either Spotfire/Tableau/Clickview and/or custom built solutions
  • Experience with big data manipulation and analysis using varying frameworks/tools: SQL, Python, R, SAS
  • Strong written and verbal communications skills; comfortable communicating with senior levels of both business and technology leadership
  • Experience driving large analytic projects and programs to completion
  • Strong practical knowledge of analytical techniques and methodologies such as machine learning/supervised and unsupervised techniques, segmentation, mix and time series modeling, response modeling, lift modeling, experimental design, neural networks, data mining, Bayesian inference, and optimization techniques
  • Good organizational and communication skills, the ability to work in a collaborative environment, and a desire to improve skills are essential

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Online Neuroscience Community Specialist

Date Posted:
4/14/2017

Society for Neuroscience

DC

Online Neuroscience Community Specialist

The Society for Neuroscience (SfN) is searching for a Community Specialist who will be responsible for the growth of the community and discussion areas of SfN's learning and discussion website, Neuronline.  This role will work with other programmatic departments to help facilitate the growth of smaller communities, along with evolving the strategy and initiatives within our digital community for the benefit of our members. The Specialist must have excellent communication skills, have knowledge of the field, and interest in social media. This would be ideal for a candidate with a science background that has an aptitude for online technology and communication.

ESSENTIAL JOB FUNCTIONS include the following. Other duties may be assigned.

Member Engagement/Online Community Management

  • Coordinate and participate in the development and implementation of strategies to increase member engagement on the Neuronline community and discussion site.
  • Develop and grow SfN programs to encourage member engagement.
  • Serve as a neuroscience subject matter expert to cultivate community for SfN members, and use that neuroscience expertise to seed conversations and connect members with like interests to one another.
  • Cultivate relationships with SfN staff "moderators" (internal SfN staff who manage society programs), helping to grow Neuronline's programmatic communities.
  • Lead monitoring of member engagement on the Neuronline community site, providing regular data, reports, and analysis on member participation and activity.
  • Lead monitoring of member discussions taking place on comment threads and in the forums.
  • Coordinate with staff from other SfN departments to integrate discussion of the SfN annual meeting, The Journal of Neuroscience, eNeuro, and other content into the forums.

Marketing/Communications

  • Lead smooth planning and implementation of Neuronline-related promotional activities and events at the SfN annual meeting in consultation with SfN's communication and marketing departments.
  • Lead the brainstorming for annual meeting and year-round marketing initiatives for Neuronline forums, working closely with communication and marketing departments.

Technology

  • Serve as first responder to any technical problems that arise within the forums, working with the platform vendor and internal technical support staff.
  • Become an expert in the community/discussion software, Discourse.
  • Learn Sitecore, the Content Management System (CMS), to enter content (written articles, video, audio) and set up pages for the Neuronline website.
  • Work in the CMS to review and troubleshoot content prior to it going live on Neuronline.

Content Development

  • Write and edit content and interview scientific experts and members as needed.
  • Draft marketing text to be distributed through SfN's e-newsletter, the SfN website,N communications vehicles

MINIMUM REQUIREMENTS:

Supervisory Experience:

  •  None.

Education and Experience:

  • Bachelor's degree in Neuroscience or other relevant field required; Master's degree or PhD preferred
  • Experience with science communication.
  • Basic understanding of publishing online content, and ability to quickly learn new software; HTML and content management experience preferred
  • Experience facilitating on-line or in-person group discussion

Preferred Qualifications:

  • Excellent oral, written, and interpersonal communication skills.
  • Ability to multitask and set priorities, take initiative, and work within a collaborative team environment.
  • Able to plan and execute tasks, on schedule and with attention to detail.
  • Strongly proficient with Microsoft Office applications, and Internet research.
  • Functional ability in CSS considered a strong asset.
  • Experience working in Content Management Systems considered a strong asset.
  • Ability to learn and master an online community management system.
  • Strong organizational and project management skills with the ability to coordinate a diverse set of activities.

If this is you and you are eager to make meaningful contributions to a highly relevant and important mission, please submit a cover letter with your salary requirements and a copy of your resume for consideration. Applications without cover letters will not be considered.

The Society for Neuroscience is wholly dedicated to recruiting, developing, and retaining a diverse group of talented people.  We are committed to provide equal opportunities to all employees and applicants without regard to race, color, religion, gender, national origin, age, disability, sexual orientation, gender identity, or other protected criteria, in accordance with applicable law and we welcome Veteran applicants.

Our generous benefits package includes:  medical, dental, disability and life insurance; flexible spending accounts, two retirement plans with employer matching and nonmatching contributions; 12 days of paid vacation, 12 days of paid sick leave, with additional personal leave and 10 paid holidays; gym membership reimbursement; and tuition reimbursement.

Apply at https://sfncareers.applicantpro.com/jobs/503896.html . Questions can be directed to Blythe Alexander (blythe.e.alexander@gmail.com). 


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Immunology Scientist I

Date Posted:
4/9/2017

Aeras

MD

Job Description:

The Scientist I is a member of the Human Immunology team, with primary responsibilities in the area of clinical sample logistics and analysis using standard laboratory practices and, when necessary, Good Laboratory Practices or Good Clinical Laboratory Practices.

The Scientist I works under minimal supervision; requires ability to exercise good judgment and discretion in handling assigned responsibilities, including the ability to resolve problems.? Functions are to be completed in a timely manner with acceptable quality.??

Essential Duties and Responsibilities:

Primary Duties and responsibilities shall include, but are not limited to the following:

  • Conducts immunological and general laboratory procedures, using standard laboratory practices, Good Laboratory Practices when appropriate, and Biosafety Level 2 (BSL-2) procedures
  • Works cross-functionally within the Pre-Clinical department to meet organizational objectives
  • Develops, performs, and analyzes data from new immune assays, including expanded flow cytometry panels, ELISpot assays, ELISAs, and other immunological assays
  • Works with collaborators to bring new technology into Aeras as assigned by the Sr. Director of Human Immunology
  • Leads assay validation, QC procedures, and writing, maintenance and updating of laboratory SOPS
  • Ensures the maintenance of complete and clear laboratory notebooks; generates lab progress reports, study protocols, and study reports
  • Presentation of data at internal, national, and international meetings and generates manuscripts for submission to journals
  • Lead cross-functional pre-clinical project development teams as assigned
  • Serve as Immunology representative on assigned product development teams
  • Leads in further development of processes regarding shipping, receiving, recording, storing, and data management of all clinical trial samples
  • Ensures completion of routine laboratory maintenance, including reagent inventory, instrument calibration, and facility monitoring

Qualifications and Requirements:

  • Ph.D. in Immunology or related field with at least two (2) years of experience or a Master?s degree in Immunology or related field with at least five (5) years relevant industry experience
  • Broad background in immunology, including cellular immunology
  • Experience in multi parameter flow cytometry and data analyses, primary human cell culture and PBMC cryo-preservation, and the skills to prepare reports of primary and analyzed data
  • Flexibility in work hours to accommodate cell processing and immunoassay schedules
  • Must maintain a professional demeanor, as well as a pleasant manner and positive ?can-do? attitude while developing and maintaining communications in a cooperative and collaborative manner with all levels across functional teams both internally and externally
  • Flexibility to change priorities and be comfortable with the changing deadlines to meet organization needs when required
  • Must be detail-orientated, with the ability to work on multiple projects while staying on top of them from start to finish and completing projects with acceptable timeliness and quality
  • Highly motivated and a self-starter; demonstrated ability to work independently, as well as in a team while exercising discretion; takes initiative to resolve problems
  • Effective communication (both orally and in writing) and excellent listening skills; strong customer service orientation and interpersonal skills
  • Demonstrated ability to seek, learn and apply new skills/knowledge to perform job responsibilities
  • Follows all company safety practices, Standard Operating Procedures (SOP?s) and policies
  • Excellent computer literacy and ability to learn new software quickly; proficient user of MS Office (Word, Excel, PowerPoint and Outlook) and common business equipment

Preferred Qualifications:

  • Relevant industry experience
  • Experience in characterization and engineering of monoclonal antibodies
  • Experience in qualification/validation of immune assays
  • Training and publication history related to antibody immunology and assay development, such as ELISAs, and BAMA
  • Training and publication history related to human B cell such as B cell ELISpot/FluoroSpot, isotyping, and generation of hybridomas

Location:

Rockville, MD, USA

How to Apply:

Click?HERE?to apply for this position.

Reference code: R10-17

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Associate Editor

Date Posted:
4/9/2017

AAAS

DC

Who We Are

"The advancement of science should be the chief concern of a nation that would conserve and increase the welfare of its people."

-James McKeen Cattell, former AAAS President and Editor of Science

The American Association for the Advancement of Science (AAAS) is an international non-profit organization dedicated to advancing science for the benefit of all people. For over a century, AAAS has been a force for science, from helping to establish science as a credible field in the 19th century to using satellite imaging technology to document human rights abuses in 2007. We are recognized as the world’s largest general scientific society and the proud publisher of the Science family of journals. Past presidents have included astronomer Edward Charles Pickering, anthropologist Margaret Mead, and biologist Stephen Jay Gould. Our mission is centered on the belief that STEM research and education can help solve many of the challenges the world faces today.

AAAS is a culture steeped in history, but adaptive to change and new ideas. We recognize the hard work of our employees and encourage the development of our staff. Our colleagues represent an array of expertise from scholarly publishing to digital marketing, educational research to government relations, all with a shared focus on mission. At AAAS, you are part of a talented team, dedicated to advancing science and serving society.

Work With Us

Science Translational Medicine is seeking a talented scientist or physician scientist interested in biomedical research to join the editorial team in Washington DC, USA or Cambridge, UK. The core responsibility of this role will be to manage the evaluation and review of manuscripts for Science Translational Medicine, an interdisciplinary medical journal established in 2009, which covers translational and clinical research in a range of biomedical fields. 

The Associate Editor position is a full-time position designed for a PhD scientist, MD/PhD physician scientist or MD with research experience. Candidates should have a lively curiosity, excellent communication skills and experience with cutting-edge translational research in genetics/genomics together with one of the following fields: modeling, statistics, big data, precision medicine. Interested candidates must submit a resume and cover letter by April 22, 2017.

Essential Duties and Responsibilities:

  • Manage the evaluation,  review, and editing of submitted manuscripts in one or more of the biomedical fields mentioned above
  • Judge the scientific value of research and select reviewers for submitted manuscripts
  • Discuss and make recommendations regarding manuscripts and reviews with other staff, advisors, authors
  • Write summaries of research results for publication
  • Guide authors on manuscript revisions and edit the manuscripts for scientific content and style before and after revisions
  • Follow manuscripts through the production process to ensure material is published in a timely manner
  • Commission and edit Review, Perspective and Focus articles on a broad range of topics
  • Commission and edit review and opinion content for special issues with the rest of the editorial team
  • Foster relationships and communication with the scientific community through meetings and professional contacts
  • Represent Science Translational Medicine at scientific meetings nationally and internationally.

Key Requirements:

  • Mastery of a professional field typically acquired through completion of a doctoral or medical degree in at least one biomedical or clinical research field
  • 2 to 5 years post PhD or MD experience, including postdoctoral research experience in one or more translational fields and multiple publications
  • Ability to work constructively as a member of a tight-knit dynamic team
  • Comprehensive knowledge of scientific research methods in order to discuss technical issues with authors
  • Exceptional written, communication, and listening skills in order to communicate with authors and reviewers in evaluating, editing and modifying manuscripts
  • Prior scientific editorial experience is not essential but is an advantage. 

Application Process:

Interested candidates should submit a resume and brief cover letter outlining qualifications and interest in the position by April 22, 2017. Up to three writing or other work samples may also be included as separate documents with your application. If we think you might be a good fit for the role, we will contact you with next steps.

AAAS is an EO employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sexual orientation, gender, gender identity, national origin, age, disability, veteran status, or other protected category. AAAS uses E-Verify to confirm the employment eligibility of all newly hired employees.

Learn More:

Visit https://www.aaas.org/ to learn more about what we do

Meet current staff and learn about our office culture on The Muse:

https://www.themuse.com/companies/americanassociationfortheadvancementofscience

Find our latest job opportunities at: https://www.aaas.org/page/employment-aaas

 


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Editing Independent Contractor

Date Posted:
4/9/2017

American Journal Experts

NC

At American Journal Experts (AJE), we help researchers successfully communicate their work through trusted author-oriented solutions to overcome the barriers to the manuscript preparation process. We are actively recruiting independent contractors from a variety of Life Science fields to edit scholarly manuscripts originally written by non-native English speakers so that language is not a barrier to research communication. AJE's independent contract editors work remotely from anywhere with a stable internet connection, can edit within their areas of academic expertise and are compensated based on manuscript length. If editing assignments are made available to the contractor pool, contract editors are under no obligation to accept assignments.

Our current needs are in the following fields:

  • Animal sciences
  • Biochemistry
  • Biomedical engineering
  • Biotechnology and bioengineering
  • Cell biology
  • Cell and tissue engineering
  • Ecology
  • Evolutionary and developmental biology
  • Interdisciplinary biology
  • Microbiology
  • Molecular biology and genetics
  • Neuroscience
  • Paleobiology
  • Zoology and plant sciences
  • Veterinary medicine

To qualify as an independent contract editor, applicants must:


The ideal applicant for this position would have had exposure to life science literature. The candidates who have been most successful in the contract editor role are autonomous, have editing experience and/or strong technical writing skills, and seek to make a positive impact on their field of expertise.


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Scientist I

Date Posted:
4/9/2017

Leidos

MD

Leidos Biomedical Research, Inc. (LBRI), a wholly owned subsidiary of Leidos, operates the Frederick National Laboratory for Cancer Research (FNLCR). FNLCR is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI). It is the only FFRDC dedicated to biomedical research. Through its status as an FFRDC, FNLCR provides NCI and others with a unique national resource to accelerate the development and delivery of effective preventive, diagnostic, and therapeutic products for cancer and AIDS.

 

The breadth of FNLCR’s activities spans the research and development spectrum, including investigator-initiated, hypothesis-driven research into cancer and AIDS; advanced technology programs focused on genetics and genomics, proteins and proteomics, imaging, nanotechnology, bioinformatics, and laboratory animal sciences; clinical operations in support of NCI and National Institute of Allergy and Infectious Diseases (NIAID)-sponsored clinical trials, as well as NCI drug discovery and development efforts; and management and operations of biopharmaceutical development and manufacturing programs under current Good Manufacturing Practice conditions for NCI and NIAID. Administrative, procurement, financial, safety, and facilities support is provided to these R&D activities through state-of-the-art business processes.  LBRI has approximately 1,900 employees and manages an annual operating budget of approximately $450M. 

 

For more information about Leidos Biomedical Research Inc., please visit our webpage at http://www.leidosbiomed.com/


PROGRAM DESCRIPTION

The Strategic Pilots Incubator (SPI) is responsible for the development and management of a portfolio of exploratory projects that are inherently multidisciplinary that impact cancer research and treatment. Projects aim to analyze the complex interactions in tumor cells and tissues and model systems, blending the best of new physics and engineering based advances with established technologies enabling new opportunities for deeper understanding of tumor biology and cancer progression.  Using the latest tools in understanding human performance under stressful conditions can be used to understand and hopefully mitigate the toxic effects of cancer therapy for the patient.

 

JOB DESCRIPTION

This position description does not represent a current opening but may be used to identify candidates with skills and experience for positions within Leidos Biomedical Research that frequently become available. Candidates who express an interest may be considered for future positions at Leidos Biomedical Research

 

We are currently recruiting for an experienced biomedical engineer or scientist to support a newly established High Content Pathology Facility at the Frederick National Laboratory for Cancer Research. The new facility will revolve around tissue and single cell analysis, including circulating tumor cells, with the newly acquired Helios Imaging Mass Cytometer, as well as single cell sequencing.  We are looking for a self-motivated and proactive individual interested in a cutting-edge and developing technology.  The successful candidate will be taking on a pivotal role in the set up and running of the new High Content Pathology Facility.  Subsequent to onsite training, candidates will be expected to be skilled in single cell imaging analysis, CyTOF mass cytometry and to develop and implement different applications of this technology. 

 

The Scientist I will be responsible for:  1) Setting up and technically validating a single cell analysis laboratory at FNLCR, 2) Developing software and macros for running instrumentation, 3) the daily management and operation of the imaging system and CyTOF, 4) establishing standardized operating procedures (SOP), 5) assisting scientists in experimental design and setup, 6) setting up and maintaining an antibody bank and reagent base, and 7) data analysis.

 


Qualifications:
BASIC QUALIFICATIONS

  • Possession of a PhD degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) in Biomedical Science, Physical Science, Engineering, Health Care Informatics or related field or eight (8) years equivalent experience in lieu of degree.
  • Foreign degrees must be evaluated for U.S. equivalency
  • No work experience beyond the doctorate education is required for appointment at this level; however, some candidates may have had one or more years of postdoctoral research and training.
  • Strong bioengineering background with expertise in handling and analyzing large data sets including imaging data, genomic, and digital histopathology
  • Experience in microscopy and image acquisition/analysis
  • Proficiency in R and/or Python programming
  • Proficiency with Microsoft Office including Excel
  • Ability to learn new techniques and troubleshoot assays

PREFERRED QUALIFICATIONS

  • Experience with antibody assay development
  • Prior experience with mass cytometry or flow cytometry
  • Experience with tissue and blood sample handling
  • Advantageous skills: immunocytochemistry (ICC) and immunohistochemistry (IHC) techniques
  • Familiar with usage of a Laboratory Information Management System (LIMS)


Leidos Overview:
Leidos is a global science and technology solutions leader working to solve the world’s toughest challenges in the defense, intelligence, homeland security, civil, and health markets. The company’s 33,000 employees support vital missions for government and commercial customers. Headquartered in Reston, Virginia, Leidos reported pro forma annual revenues of approximately $10 billion for the fiscal year ended January 1, 2016 after giving effect to the recently completed combination of Leidos with Lockheed Martin's Information Systems & Global Solutions business (IS&GS). For more information, visit www.Leidos.com. The company’s diverse employees support vital missions for government and commercial customers. Qualified women, minorities, individuals with disabilities and protected veterans are encouraged to apply. Leidos is an Equal Opportunity Employer.


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Bioinformatics Analsyt

Date Posted:
4/9/2017

Leidos

MD

Leidos Biomedical Research, Inc. (LBRI), a wholly owned subsidiary of Leidos, operates the Frederick National Laboratory for Cancer Research (FNLCR). FNLCR is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI). It is the only FFRDC dedicated to biomedical research. Through its status as an FFRDC, FNLCR provides NCI and others with a unique national resource to accelerate the development and delivery of effective preventive, diagnostic, and therapeutic products for cancer and AIDS.

 

The breadth of FNLCR’s activities spans the research and development spectrum, including investigator-initiated, hypothesis-driven research into cancer and AIDS; advanced technology programs focused on genetics and genomics, proteins and proteomics, imaging, nanotechnology, bioinformatics, and laboratory animal sciences; clinical operations in support of NCI and National Institute of Allergy and Infectious Diseases (NIAID)-sponsored clinical trials, as well as NCI drug discovery and development efforts; and management and operations of biopharmaceutical development and manufacturing programs under current Good Manufacturing Practice conditions for NCI and NIAID. Administrative, procurement, financial, safety, and facilities support is provided to these R&D activities through state-of-the-art business processes.  LBRI has approximately 1,900 employees and manages an annual operating budget of approximately $450M. 

 

For more information about Leidos Biomedical Research Inc., please visit our webpage at https://www.leidos.com/about/companies/leidos-biomedical-research.

 

PROGRAM DESCRIPTION

The Advanced Biomedical Computing Center (ABCC) is a part of the Data Science and Information Technology Program at Leidos Biomedical Research, Inc. The ABCC provides technology development, scientific consultation, collaboration and training, and high-performance computing support to the NCI and NIH scientists and staff. 

 

JOB DESCRIPTION

This position description does not represent a current opening but may be used to identify candidates with skills and experience for positions within Leidos Biomedical Research that frequently become available. Candidates who express an interest may be considered for future positions at Leidos Biomedical Research.

 

The ABCC is seeking Bioinformatics Analyst candidates at all levels to work in the NCI Center for Cancer Research (CCR) Collaborative Research Resource (CCBR). The CCBR provides collaborative bioinformatics support to CCR investigators at the National Cancer Institute (NCI). CCBR bioinformatics analysts are responsible for (i) the analysis and interpretation of high-throughput biomedical data generated by microarray, next-generation sequencing, proteomics and metabolomics platforms (ii) designing, developing and deploying robust workflows, as well as custom scripts, to support the analysis of high-throughput data (iii) mining proprietary and publicly available biological data to generate novel hypotheses or insights and (iv) presenting analysis results, in a clear and concise manner, to scientific audiences. Bioinformatics Analysts are expected to work effectively as a member of a team; coordinate activities among other groups located at the Bethesda, Frederick, Rockville and Gaithersburg NCI campuses; follow sound scientific practices and maintain effective documentation of activities and analyses.  Majority of time will be spent on the main NIH campus in Bethesda.

 


Qualifications:
BASIC QUALIFICATIONS

  • Bachelor’s, Masters or PhD degree in life science/bioinformatics/math/physics/computer related field from an accredited college according to the Council for Higher Education Accreditation (CHEA)  
  • Foreign degrees must be evaluated for U.S. Equivalency.

 

Below are the typical skills we are looking for in candidates:

 

  • Processing high throughput biomedical data: data cleaning, normalization, analysis, interpretation and visualization
  • Data analysis for complex experiments
  • Experience with high throughput analysis pipelines such as, metagenomics, ChIPSeq, RNASeq, ExomeSeq, microarray analysis
  • Experience in using tools for NGS data-processing tools
  • Familiarity with public databases: NCBI, Ensembl, TCGA, cBioPortal, Broad FireHose
  • Knowledge of database programming and working in a cluster environment
  • Ability to work in collaborative environment and contribute to team projects
  • Ability to work without close supervision

Below are the desired skills we are looking for in candidates:

  • Applied statistics and design of experiments
  • Application development experience
  • Experience in submitting data sets to public repositories
  • Management of large genomic data sets including integration with data available from public sources
  • Knowledge of cancer biology
  • Experience with bioinformatics tools such as: Novoalign, STAR, BWA, GATK, Samtools, Annotator, SnpEff, Limma, EdgeR, DESeq2
  • Proficiency in one, preferably two, of the following programming languages: Perl, Python, R, Java and C/C++

This position description does not represent a current opening but may be used to identify candidates with skills and experience for positions within Leidos Biomedical Research that frequently become available. Candidates who express an interest may be considered for future positions at Leidos Biomedical Research


Leidos Overview:
Leidos is a global science and technology solutions leader working to solve the world's toughest challenges in the defense, intelligence, homeland security, civil, and health markets. The company's 33,000 employees support vital missions for government and commercial customers. Headquartered in Reston, Virginia, Leidos reported pro forma annual revenues of approximately $10 billion for the fiscal year ended January 1, 2016 after giving effect to the recently completed combination of Leidos with Lockheed Martin's Information Systems & Global Solutions business (IS&GS). For more information, visit www.Leidos.com. The company's diverse employees support vital missions for government and commercial customers. Qualified women, minorities, individuals with disabilities and protected veterans are encouraged to apply. Leidos is an Equal Opportunity Employer.

Other Locations:  

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Bioinformatics Analsyt

Date Posted:
4/9/2017

Leidos

MD

Leidos Biomedical Research, Inc. (LBRI), a wholly owned subsidiary of Leidos, operates the Frederick National Laboratory for Cancer Research (FNLCR). FNLCR is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI). It is the only FFRDC dedicated to biomedical research. Through its status as an FFRDC, FNLCR provides NCI and others with a unique national resource to accelerate the development and delivery of effective preventive, diagnostic, and therapeutic products for cancer and AIDS.

 

The breadth of FNLCR’s activities spans the research and development spectrum, including investigator-initiated, hypothesis-driven research into cancer and AIDS; advanced technology programs focused on genetics and genomics, proteins and proteomics, imaging, nanotechnology, bioinformatics, and laboratory animal sciences; clinical operations in support of NCI and National Institute of Allergy and Infectious Diseases (NIAID)-sponsored clinical trials, as well as NCI drug discovery and development efforts; and management and operations of biopharmaceutical development and manufacturing programs under current Good Manufacturing Practice conditions for NCI and NIAID. Administrative, procurement, financial, safety, and facilities support is provided to these R&D activities through state-of-the-art business processes.  LBRI has approximately 1,900 employees and manages an annual operating budget of approximately $450M. 

 

For more information about Leidos Biomedical Research Inc., please visit our webpage at https://www.leidos.com/about/companies/leidos-biomedical-research.

 

PROGRAM DESCRIPTION

The Advanced Biomedical Computing Center (ABCC) is a part of the Data Science and Information Technology Program at Leidos Biomedical Research, Inc. The ABCC provides technology development, scientific consultation, collaboration and training, and high-performance computing support to the NCI and NIH scientists and staff. 

 

JOB DESCRIPTION

This position description does not represent a current opening but may be used to identify candidates with skills and experience for positions within Leidos Biomedical Research that frequently become available. Candidates who express an interest may be considered for future positions at Leidos Biomedical Research.

 

The ABCC is seeking Bioinformatics Analyst candidates at all levels to work in the NCI Center for Cancer Research (CCR) Collaborative Research Resource (CCBR). The CCBR provides collaborative bioinformatics support to CCR investigators at the National Cancer Institute (NCI). CCBR bioinformatics analysts are responsible for (i) the analysis and interpretation of high-throughput biomedical data generated by microarray, next-generation sequencing, proteomics and metabolomics platforms (ii) designing, developing and deploying robust workflows, as well as custom scripts, to support the analysis of high-throughput data (iii) mining proprietary and publicly available biological data to generate novel hypotheses or insights and (iv) presenting analysis results, in a clear and concise manner, to scientific audiences. Bioinformatics Analysts are expected to work effectively as a member of a team; coordinate activities among other groups located at the Bethesda, Frederick, Rockville and Gaithersburg NCI campuses; follow sound scientific practices and maintain effective documentation of activities and analyses.  Majority of time will be spent on the main NIH campus in Bethesda.

 


Qualifications:
BASIC QUALIFICATIONS

  • Bachelor’s, Masters or PhD degree in life science/bioinformatics/math/physics/computer related field from an accredited college according to the Council for Higher Education Accreditation (CHEA)  
  • Foreign degrees must be evaluated for U.S. Equivalency.

 

Below are the typical skills we are looking for in candidates:

 

  • Processing high throughput biomedical data: data cleaning, normalization, analysis, interpretation and visualization
  • Data analysis for complex experiments
  • Experience with high throughput analysis pipelines such as, metagenomics, ChIPSeq, RNASeq, ExomeSeq, microarray analysis
  • Experience in using tools for NGS data-processing tools
  • Familiarity with public databases: NCBI, Ensembl, TCGA, cBioPortal, Broad FireHose
  • Knowledge of database programming and working in a cluster environment
  • Ability to work in collaborative environment and contribute to team projects
  • Ability to work without close supervision

Below are the desired skills we are looking for in candidates:

  • Applied statistics and design of experiments
  • Application development experience
  • Experience in submitting data sets to public repositories
  • Management of large genomic data sets including integration with data available from public sources
  • Knowledge of cancer biology
  • Experience with bioinformatics tools such as: Novoalign, STAR, BWA, GATK, Samtools, Annotator, SnpEff, Limma, EdgeR, DESeq2
  • Proficiency in one, preferably two, of the following programming languages: Perl, Python, R, Java and C/C++

This position description does not represent a current opening but may be used to identify candidates with skills and experience for positions within Leidos Biomedical Research that frequently become available. Candidates who express an interest may be considered for future positions at Leidos Biomedical Research


Leidos Overview:
Leidos is a global science and technology solutions leader working to solve the world's toughest challenges in the defense, intelligence, homeland security, civil, and health markets. The company's 33,000 employees support vital missions for government and commercial customers. Headquartered in Reston, Virginia, Leidos reported pro forma annual revenues of approximately $10 billion for the fiscal year ended January 1, 2016 after giving effect to the recently completed combination of Leidos with Lockheed Martin's Information Systems & Global Solutions business (IS&GS). For more information, visit www.Leidos.com. The company's diverse employees support vital missions for government and commercial customers. Qualified women, minorities, individuals with disabilities and protected veterans are encouraged to apply. Leidos is an Equal Opportunity Employer.

Other Locations:  

APPLY NOW    


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Molecular Biology Postdoc

Date Posted:
4/9/2017

Mesa Biotech

CA

Job Description

A motivated and independent molecular biology R&D postdoc scientist is sought to work on
the development of the next generation of molecular nucleic acid disease diagnosis kits. The
ideal candidate will have at a minimum, demonstrated biochemistry and molecular biology
expertise and experience with PCR and Real Time-PCR diagnostic technology. The successful
candidate will design nucleic acid amplification primer and probes for infectious disease
pathogens, develop/optimize molecular diagnostic assays for human infectious diseases and
incorporate the developed assay chemistry into the integrated diagnostic device, validate the
diagnostic device using well-characterized clinical samples. The experience of fluorescencebased
real time PCR measurement, and handling BSL-2 (pathogen) is required. The
successful applicant must work within an integrated multidisciplinary laboratory and be able
to work with other scientists, technicians and students in the team. In addition, the technician
will be expected to interact and work effectively with a demanding, fast-paced biotech startup
environment.

Requirements

Demonstrated experience with PCR, real time PCR methods
• Bioinformatic primer/probe design experience and hand-on experience of PCR assay
development, optimization and clinical validation
• Hands on experience with handling BSL-2 human pathogens
• Experience of clinical sample validation and statistical analysis
• Excellent presentation and written skills
• Excellent team working and communication skill


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Sr. Scientist Medicinal Chemistry

Date Posted:
4/9/2017

BioDuro - Shanghai China

INT

BioDuro, a Bridgewest company, is a leading life sciences research organization that provides biopharmaceutical clients with comprehensive, integrated drug discovery services spanning from target identification through Phase 0.  With depth and breadth of therapeutic expertise in small molecule discovery, and large molecular development and scale up, combined with unique technology platforms, BioDuro is well positioned to help clients significantly accelerate their lead discovery programs.
With its headquarters located in San Diego, California, the company was established in Beijing in 2005. It opened its branches and drug discovery center in Shanghai and Nanjing in 2012 and 2013 respectively. BioDuro’s global operations include a total of nearly 600 employees in Santiago, Beijing, Shanghai and Nanjing. It has a 100,000 sf facility in Beijing, a 92,000 sf state of the art facility in Shanghai, and a team of highly experienced research staff and scientists, of whom 20% own Phd degree and 15% overseas background.  
With the highest concentration of drug discovery expertise of any contract research organization (CRO) in China and a broad range of capabilities in chemistry, discovery biology, drug metabolism and pharmacokinetics (DMPK), pharmacology, as well as integrated preclinical research and development services, BioDuro brings superior insight and innovative solutions to its clients’ drug discovery programs. Through a strategic partnership with X-Chem Inc., BioDuro is able to conduct innovative hit and lead generation by using its proprietary DNA-based chemical libraries, giving the clients access to large, diverse libraries of compounds that can be used to better interrogate a broad range of high priority drug targets, which can significantly accelerate lead discovery and improve the probability of success.
The Bridgewest Group (BBG) is a closely held investment company with global assets in the biotech and hi-tech industries. With its managed fund of more than 1.5 billion USD, BBG creates long-term value through the application of superior industry knowledge, operational expertise and significant financial resources to attractive investment opportunities. The subsidiary companies of BBG also include monoclonal antibody technique platform companies, biotech companies and pharmaceutical preparation and manufacturing companies such as Formex, BioAtla, Femta, Molecular Response, etc. Among them, Formex is a leading contract development and manufacturing organization. In July, 2015, Formex merged with BioDuro, which extended BioDuro’s new drug discovery service from pre-clinical stage to clinical field. Under the leadership of BBG, BioDuro will continue to improve its core competitiveness, expand and enhance its services and cultivate its employees to increase their research and development ability, aiming at becoming the best international drug discovery and service company of the industry.

BioDuro (Shanghai)

BioDuro (Shanghai) is a wholly-owned subsidiary of BioDuro, located at the Waigaoqiao Free Trade Zone. Same as its parent company, BioDuro (Shanghai) focuses on providing new drug discovery service. The company houses pharmaceutical chemistry, DMPK, and integrated biology and pharmacology as well as an operational team. It owns a 7,200 square meters state of the art laboratory and a 2,000 square meters office building. The 2,000 square meters laboratory for animal experiment has been approved by the AAALAC. Currently, the company has more than 150 employees and is growing rapidly.


________________________________________        
Senior Scientist in Chemistry  ?????????    

(Location: Shanghai)

Key activities: As a key member of a high performance chemistry team in BioDuro's R&D center located in Shanghai, China, you will be responsible for independently developing and optimizing synthetic routes toward synthesis of novel compounds in mg to multi-g scales.

Requirements

Requirements:
•   Ph.D. in synthetic organic chemistry with a strong scientific track record
•   Excellent problem solver
•   Be able to deliver under a tight timeline
•   Medicinal chemistry experience a plus

*candidates must have experience working in the US

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Scientist I DMPK

Date Posted:
4/9/2017

Abbvie

CA

Job Description

Pharmacyclics, an AbbVie Company, based in Sunnyvale, CA represents the single largest acquisition AbbVie has ever made, and is key to AbbVie’s corporate strategy to add another very significant growth platform and diversification. Pharmacyclics will be run as a semi-autonomous, fully integrated operating unit of AbbVie, with all functions including among others Commercial, R&D and Manufacturing. The integration into AbbVie should be minimally disruptive for Pharmacyclics; hence the identity, structures and relative independence will be minimally adapted at this time. The new President of Pharmacyclics is Erik von Borcke, currently a senior executive with AbbVie who has relocated to the Sunnyvale Area and reports to the Chairman and CEO of AbbVie, Rick Gonzalez.

The DMPK department at Pharmacyclics, Sunnyvale, CA is seeking a motivated Scientist to join the Metabolite Identification group. The responsibilities include profiling and characterization of metabolites (small molecules) from biological matrices and related ADME assays. A background in delineating biotransformation pathways and structural elucidation by LC-MS is preferred. Work closely with bioanalytical and PK scientists to integrate drug metabolism data for drug discovery and ADME data for lead optimization.  Experience with in vivo preclinical and ADME assays and understanding of clearance route, mechanism and the role of metabolism is preferred.

Key Accountabilities/Core Job Responsibilities:

   Ability to learn quickly and execute laboratory techniques essential for in vitro ADME analysis (TDI, CYP inhibition, reaction phenotyping) for lead optimization in drug discovery
   Proficiency in LC-MS method development for separation and structural identification of multiple metabolites from various matrices
   Good understanding of organic/structural elucidation chemistry, xenobiotic and extra hepatic metabolism
   Hands on experience in operation, maintenance & trouble shooting of LC-MS instruments of multiple vendors (Sciex/Thermo) and associated software’s
   Conduct in vitro drug metabolism studies, to quantify test compounds and their metabolites in various matrices including microsomes, S9 preparation, hepatocytes and in vivo PK samples
   Conduct non-radio-labeled and radio-labeled metabolite profiling experiments from in vitro and in vivo studies
   Maintain accurate records and write in vitro ADME reports for in-house studies

Requirements



   PhD degree (1-3 years) B.S. or MS degree (5-7 years) equivalent in drug metabolism or related discipline with relevant industrial experience in drug discovery/development

   Prior experience with HPLC and LC-MS are required. Familiarity with AB Sciex and/or Thermo Orbitrap high resolution mass spectrometry instruments are a must
   Experience in utilizing radio-labeled material would be preferred
   The candidate must be able to analyze data and maintain detailed, accurate and comprehensible study documentation. Experience with various scientific data base is a plus
   The individual is also expected to be organized, a team player, enthusiastic about drug discovery, and possess strong communication skills

Equal Opportunity Employer Minorities/Women/Veterans/Disabled


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Senior Principle Scientist - Cancer Immunology

Date Posted:
4/9/2017

Pfizer

CA

A career at Pfizer offers opportunity, ownership and impact. All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.



Role Description

The Cancer Vaccines & Immunotherapeutics group seeks to discover novel cancer vaccines and oncolytic viruses using a variety of technology platforms in combination with immunomodulatory agents. We are searching for a motivated individual with in-depth immunoassay experience and a prior track record in the field of oncology (preferably immuno-oncology), to join our Immunology group in San Diego, California. This position will require the successful applicant to perform the role of a line manager, overseeing and mentoring other scientists in the Cancer Immunology group, maintain an oversight presence in the laboratory as a matrix team leader charged with directly ensuring high-quality data is delivered in an organized and safe manner.



Responsibilities

The candidate will be required to: * Develop and guide strategies that advance the development of vaccine-based and oncolytic virus-based cancer immunotherapies by applying immunological knowledge to circumvent tumor microenvironment-mediated suppression of anti-tumor immune responses.
* Contribute scientific knowledge, innovation, and strategic thinking as a core member on project leadership teams by being fully accountable for the progress and success of the project whether acting as a line representative or project lead.
* Provide broad expertise in T cell immunology including the development and consistent application of immunoassays (e.g. ELISpot, flow cytometry, T cell cytotoxicity, multiplex cytokine analysis) to measure vaccine-induced cellular responses.
* Proactively apply scientific knowledge to the design of in-vivo studies that effectively answer experimental questions with high-value to project progression.
* Manage several direct reports, with responsibility for their day-to-day workload and professional development, and organize and oversee efforts of larger teams in a matrix environment.
* Apply exceptional organizational skills to overseeing the scheduling of study readouts, confirming personnel and resources are available to run required immunoassays, and ensuring all colleagues participating know their roles and responsibilities.
* Oversee rigorous QC of data and endorse study result interpretations prior to release to project teams. Responsibilities: Laboratory work (~20% of time) and other efforts will be performed with minimal supervision: * Define study aims and experimental plans with project teams and both initiate and oversee work within functional line.
* Coordinate scheduling of study readouts with project team members and Immunopharmacology line representatives.
* Organize and oversee immunoassay teams on study readouts, coordinating both the laboratory work and the generation of data in a timely fashion.
* Manage day-to-day workload of several direct reports ensuring they deliver on their goals.
* Build capacity/functionality of the Cellular Immunology team by ensuring the latest methodologies and technologies are considered and adopted as applicable.
* Analyze and interpret experimental data and subsequently present findings at appropriate project team, departmental and leadership meeting settings. Communication: * Actively contributes ideas and challenges data at Immunology line and project team meetings.
* Provides clear, concise and timely responses to project team requests for data and experimental information. Documentation: * Authorship of SOPs, study reports and protocols
* Regular entry of experimental plans and laboratory notes into an electronic notebook system in compliance with corporate policies
* Preparation of PowerPoint-based slides for presentation to project teams and senior leadership Safety: * Complies with all EH&S regulations and safe laboratory practices and is a vigilant advocate for the safety of fellow colleagues.
* Identifies and acts to reduce hazards and risks in the laboratory through use of Risk Assessments and Job-based Hazard Assessments.

Requirements

Qualifications

Qualifications: * PhD in life sciences, with a strong focus on immunology and/or immuno-oncology.
* 7+ years' experience working in a relevant laboratory setting that routinely performs cellular immunoassays to characterize immune responses. Preferred: * Prior work experience primarily based in biotech/pharmaceutical industry settings and focused around areas of cellular immunology and/or immuno-oncology.
* Research experience applying immune checkpoint inhibitor strategies to various disease areas.
* Extensive practical experience with handling/processing animal lymphoid tissues/blood and human blood samples, flow cytometry (>6-color staining) acquisition and analysis, ELISpot, multiplex cytokine (MSD, Luminex), T cell cytotoxicity, and proliferation based assays.
* Experience with high-throughput sample automation systems and developing/implementing new assays. Physical/Mental Requirements: Due to the applicant to be able to function and operate in a research laboratory; involving sitting, standing, walking, bending, ability to perform mathematical calculations and ability to perform complex data analysis. The applicant will be required to work with BSL2 infectious viruses, e.g. Vaccinia virus, adenovirus, influenza, and must receive and maintain required vaccinations or provide satisfactory proof of same. Travel and Environment Requirements: Applicant will need to travel to external research laboratories if and when required, often traveling out of normal business hours. Applicant will have to adhere to safe work practices and procedures such as aseptic laboratory practices and infectious agent handling precautions. Organizational Relationships: Will have regular interaction with project teams and other Vaccine Immunotherapeutics lines, e.g. Immunopharmacology, Formulations & Analytics, Protein and Viral Sciences. Supervision: Applicant will be required to manage several direct reports, and in addition, a matrix group of colleagues.



EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization