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Science Education Fellow in Physics

Date Posted:
4/25/2017

Stanford

CA

The Physics Department at Stanford University is seeking applications for a Science Education Fellow in Physics to support committed faculty in implementing an effective transition of physics courses to an active learning format. Fellows will typically have a recent PhD in physics and a keen interest in how learning works and how to improve it. Experience in facilitating interactive learning is desirable. The Fellow will join a cohort of Science and Engineering Education Fellows, including a current Fellow in Physics. The Fellow will be provided with training and with opportunities to engage in courses in a meaningful way, that will help to prepare the Fellow for a possible career in teaching and education. The Fellow will typically support one course per quarter in its initial transition to active learning; the course may be at any level or in any of the areas taught in a standard undergraduate physics curriculum.

A Fellow’s role will typically include the following elements in the quarters before, during, and after the course is taught: research and collect learning goals and existing active learning materials; facilitate the identification, development, and/or improvement of learning goals for the course; research and develop measures of students’ prior knowledge; work with the faculty instructor to develop activities, problem sets, pre-class preparation assignments, and other curricular materials that target the learning goals; co-teach a fraction of in-class activities, or one section (of three) per week; use Stanford resources to develop instruments to assess the effectiveness of different elements of the course and incorporate corrections; document and archive course materials using modern sustainable techniques that facilitate collaboration and sharing with other faculty; and serve as a resource in the department for other teaching-related projects. In addition to these duties, Science Education Fellows in Physics can take advantage of opportunities to organize and teach a summer course of their own, for their own professional development and credentials.

The appointment begins July 31, 2017, for a two-year term that is renewable for one additional year depending on programmatic need and job performance. Starting annual salary will be $70,000 with an additional supplement of up to $2,000/year that can be used for professional development opportunities and work-related expenses.

Applicants should submit the following materials: a letter that addresses qualifications including any relevant experience in teaching and course development, and knowledge or expertise in physics education, learning, and pedagogy; a current curriculum vitae; a teaching statement; and a summary of student, peer and/or other teaching evaluations. Application materials should be submitted using Academic Jobs Online.  https://academicjobsonline.org/ajo/jobs/9051

In addition, applicants should arrange for three letters of recommendation to be submitted by the reference writers through the Academic Jobs Online website. At least one letter writer should address the applicant’s experience or qualifications in teaching. If the applicant has not yet completed the Ph.D., one letter writer should address the status of dissertation progress toward completion by the end of June 2017.

Applications will be reviewed beginning May 1, 2017.

For further information about the position, send questions to physics-educ-fellow-info@lists.stanford.edu

Stanford University is an affirmative action and equal opportunity employer, committed to increasing the diversity of its workforce. It welcomes applications from women, members of minority groups, veterans, persons with disabilities, and others who would bring additional dimensions to the university's research and teaching mission.

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Graduate Professional Development Career Advisor

Date Posted:
4/25/2017

Johns Hopkins

MD

The Graduate Professional Development Career Advisor will provide direct career advising and workshop delivery to graduate and PhD students in the Whiting School of Engineering’s Applied Mathematics and Statistics (AMS) program. To meet this goal, the Advisor will identify, create, and implement enhanced career advising and programming for AMS graduate/PhD students, collaborate with faculty in order to assist students in AMS in their professional development and interaction within industry, and develop and maintain connections between these programs and employers.
The Advisor will work closely with colleagues at the Johns Hopkins University Career Center, based on the Homewood Campus, reporting jointly to the AMS Senior Administrator and to the Executive Director of the Homewood Career Center.
Essential Duties and Responsibilities: For the following activities, this position will report to the Senior Administrator of AMS.

  • Collaboration, Outreach, and Strategic Planning
  • Discipline-specific employer relations:
  • Establish and maintain connections with industry and governmental agencies.
  • Establish and maintain a placement inventory of alumni; devise strategies to engage alumni.
  • Collaborate and coordinate employer relations outreach, programming and events with the Homewood Career Center.
  • Develop and conduct surveys with students, AMS alumni, and employers to analyze trends and to identify gaps and opportunities. Develop long-term sustainable strategies for discipline-specific career development opportunities for students.
  • Organize discipline-specific networking events.
  • Travel domestically to maintain industry and alumni relationships.

Coaching and Mentoring:

  • Provide discipline-specific career advising, for such disciplines as financial mathematics, data mining, operations research etc., to graduate and PhD students in the context of today’s industrial environment.
  • Develop and implement comprehensive discipline-specific professional development programming (alumni panels, current student internship presentations, etc.)
  • Coach individuals and groups to develop professionally and attain their career goals, utilizing coaching techniques and resources that meet the needs of diverse populations (international students and underrepresented minorities).
  • Facilitate student exploration of their skills, interests, values and experiences in order to create a job search strategy targeted to their discipline of interest.
  • Create and deliver workshops on a wide variety of career content areas including resume or CV writing, cover letter writing, creating a job search strategy, practice interviewing and networking.
  • Make recommendations and highlight courses available and appropriate for professional development.
  • Collaborate and coordinate student programming and events with the Homewood Career Center.

Program Management/Administration:

  • Maintain social media presence including utilizing social media to keep in touch with alumni and promote the master’s programs; maintain AMS career content on departmental website.
  • Manage AMS Career Development budget.
  • Hire student workers and oversee projects assigned to them.
  • Collaboration with Homewood Career Center and Other University Offices - For the following activities, this position will report to the Executive Director of the JHU Career Center.
  • Collaborate with the Employer Relations team at the Homewood Career Center when identifying and reaching out to employers to ensure coordination across JHU.
  • Partner with colleagues at the Homewood Career Center and in the Office of International Services to create programming and services specific to the challenges international students face in fellowship applications and job searches.
  • Coordinate strategic activities and programming with Homewood Career Center staff to ensure alignment, encourage coordination, identify the intersections of career services initiatives, and ensure consistent delivery of services.
  • Manage and track relevant data including internships, percentages of students doing internships, length of internships, trends, using career services management software where applicable. Share with colleagues at Homewood Career Center and other university administrators regularly and as requested for reporting purposes.
  • Working with colleagues at the Homewood Career Center and elsewhere around the university, build and maintain a network of professionals and alumni across varied careers who can attend networking and career exploration events.
  • Collaborate with Homewood Career Center colleagues to design, plan career development activities and events that promote personal and professional development in collaboration with students, advisors, faculty, alumni and others as relevant.
  • Partner with Homewood Career Center colleagues to establish and maintain connections with industry, governmental and non-governmental agencies.
  • Partner with Homewood Career Center and Development & Alumni Relations colleagues to establish and maintain a placement inventory of alumni; devise strategies to engage alumni.
  • Cultivate and strengthen relationships with colleagues across units, including, but not limited to, academic departments, academic advising, student affairs, and international services.



Qualifications

Education and Experience:
Master’s degree required. PhD preferred. Three-five years of experience required in higher education or in an industry related field (such as finance, banking, information technology, and health care).
Abilities and Skills

  • High proficiency in the use of traditional and online resources (e.g. LinkedIn) for career development.
  • Knowledge of the role of applied mathematics and finance in industry (strongly preferred).
  • Experience working with international students whose first language is not English (strongly preferred).
  • Confident, resourceful and self-directed individual with strong interpersonal skills, high emotional intelligence, and excellent oral and written communications skills.
  • Demonstrated capacity to work effectively with persons from diverse backgrounds to promote an inclusive campus and community culture.
  • Demonstrated skill in fostering new institutional relationships, and marshaling professional networks with faculty, senior administrators, employers and alumni.
  • Demonstrated experience in a higher education environment involving students, employers and/or alumni. Preferred experience in advising or mentoring students.
  • Ability to make decisions and work independently and to collaborate as a member of a team.
  • Knowledge of US immigration regulations as they affect employment of international students (CPT, OPT, etc.).

Additional Requirements:

  • Work occasional evenings or weekends as needed.
  • Some domestic travel may be required.



Preferred Qualifications

  • Significant experience working with international populations.
  • Teaching and/or training experience
  • Expertise and experience in presenting and training of large groups
  • Experience as a recruiter or with a professional placement firm.



NOTE: The successful candidate(s) for this position will be subject to a pre-employment background check.

If you are interested in applying for employment with The Johns Hopkins University and require special assistance or accommodation during any part of the pre-employment process, please contact the HR Business Services Office at 443-997-5100. For TTY users, call via Maryland Relay or dial 711.

Note: Job postings are updated daily and remain online until filled. See more in our FAQ .
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Assistant Director of Graduate Education

Date Posted:
4/25/2017

University of Virginia

VA

The School of Engineering & Applied Science (SEAS) at the University of Virginia invites applications for the position of Assistant Director of Graduate Education. The Assistant Director works with the Director of Graduate Education and the Graduate Programs Office toward the planning, development, and implementation of SEAS-wide programs and initiatives that support UVA Engineering graduate students.  This position will also work with the Center for Engineering Career Development to provide career advising for graduate engineering students and postdocs.

The successful applicant will possess excellent communication and interpersonal skills, and a strong desire to work with students, faculty, and administrators from across the School and University.  Broad knowledge of higher education policies and procedures, and significant experience with advising and mentoring graduate students is preferred.  Organizational and analytical skills are highly desired, as is a Ph.D. or terminal degree in any STEM field or in higher education.

 

Duties

Graduate Student Affairs and Recruitment (50%)

  • Work with the Director of Graduate Education to implement strategies and policies related to and impacting graduate affairs in SEAS
  • Help develop and execute a pro-active, year-round graduate student recruitment program that will include activities such as attendance and recruitment at key conferences, the planning and organizing of on-Grounds graduate recruitment events, and collaboration in the development of effective and up-to-date marketing materials
  • Assist in the development and implementation of strategies and initiatives to increase under-represented groups in the SEAS graduate student body
  • Gather, review, and report on graduate student data (e.g. applications, admissions, retention, diversity, and first destination outcomes)
  • Along with the Graduate Programs Office, oversee the content in the Graduate Record and on the SEAS Graduate website
  • Organize new graduate student orientation
  • Perform other duties and special projects as needed
  • Assist the Director of Graduate Education in developing programs to prepare students to be professionals and leaders in their fields.

 

Career and Professional Development (50%)

  • Advise students on career development, including self-assessment, career decision-making, CV/resume critiques, and job search strategies (both academic and non-academic). 
  • Assist graduate students in designing personalized professional development plans
  • Create and present career development events and workshops including how to approach academic and non-academic job searches, networking, CV and resume writing, interviewing, salary negotiation, and job offer decision making
  • Build relationships with alumni and professionals with the goal of expanding the career connections for graduate students and to strengthen our relationships with potential employers
  • Plan and organize programs that connect employers and alumni with students, including networking events, career panels and employer site visits
  • Develop relationships and collaborate with Engineering faculty, staff and the career services community across Grounds
  • Develop procedures to effectively evaluate programs and student services for graduate students. ?Analyze data and prepare statistical reports as needed.
  • Research program trends and challenges at peer institutions and make informed recommendations for programming. Attend annual conference for Graduate Career Consortium and related events.
  • Help develop appropriate internship and experiential opportunities for graduate students.
  • Assist graduate students in securing employment post-graduation, including post-doctoral positions, faculty positions, entrepreneurship and roles in government and provate industry.
  • Collaborate with the Director of Communications to promote our PhD students to faculty and Deans at other institutions

 

Application

To apply, visit https://jobs.virginia.edu/applicants/jsp/shared/frameset/Frameset.jsp?time=1492805720433. Reference job # 0620784.  Complete a Staff Application online, attach a cover letter, resume, and contact information for 3 references. The position will remain open until filled.  Any questions may be sent to shannon.barker@virginia.edu.

 

The University of Virginia is an equal opportunity and affirmative action employer.  Women, minorities, veterans, and persons with disabilities are encouraged to apply.

 

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Medical Writer !

Date Posted:
4/25/2017

ICON plc

PA

Description

 

This is an exciting opportunity to work within a fast-paced, environment with a team committed to being the best strategic medical communications agency in the world by leading the industry in quality, service, and innovation. At CHC Group, our value is our people, who consistently deliver the highest-quality work to our clients.

 

The Medical Writer position is an entry level position ideally suited for those looking to pursue a career in medical writing.

 

As a Medical Writer you are responsible for developing outlines, manuscripts, abstracts, scientific posters, and slide presentations across one or more therapeutic areas. The MW works closely with other Editorial and Client Services team members to meet client expectations, budgets and timelines.

 

Who Are We?

 

Through the recent acquisition of CHC Group and MediMedia Managed Markets (MMMM) LLC, ICON plc has strengthened its expertise in scientific communications and market access. ICON is a fast-growing global provider of outsourced development services to the pharmaceutical, biotechnology and medical device industries, known for its innovative approach. ICON’s core commercialization and outcomes capabilities coupled with the strategic consultancy services of CHC Group and MMMM, has created the industry’s most integrated product development, clinical communication and market access solution. This means more growth and career opportunities for our current and future employees!

 

What’s In It For You?

 

We provide our Medical Writers with a strong benefits package that includes a comprehensive health plan, retirement plans, competitive pay, vacation, and an annual incentive plan to reward performance.

 

We have a friendly environment where you can be fully engaged, motivated and rewarded. We allow you to shine because it enables us to achieve our goals. Our employees are our best asset and we encourage upward mobility by enabling them to realize their potential within a performance culture that is demanding and exciting.

 

To Succeed You Will Need

 

  • Advanced degree in life sciences (PhD, PharmD, or MD preferred, or proven record of excellence in the position)
  • Gracious and proactive ability to interact with clients
  • Ability to meet or beat deadlines every time
  • Must possess a high level of attention to detail

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Scientist II Cancer Immunology

Date Posted:
4/25/2017

Revolution

CA

REVOLUTION Medicines is an exciting, early stage biotechnology company that discovers and develops innovative drugs for cancer patients directed toward frontier oncology and immune-oncology targets.  The company draws inspiration from evolution and natural products that are inherently rich with biological function. REVOLUTION Medicines deploys an innovative toolkit including REVBLOCKS™, an integrated suite of rapid, agile, and modular synthesis methodologies applied to simple chemical “building blocks,” and the REVEAL™ computational platform, which uses evolution’s lessons to inform selection of chemical scaffolds guide drug design for non-classical drug targets. As a new member of the RevMed team, you will join other outstanding scientists who are helping lead our efforts in the discovery and development of new medicines for unmet needs in cancer.

 

The Opportunity:

As a key player in our biology team, you will:

  • Be a critical member of the cancer biology group and multi-disciplinary research project teams

  • Be accountable to the Head of Biology and Research Team Leads for performing cutting-edge cellular immunology research by integrating knowledge from tumor immunology and immunotherapy to support development of novel therapies.

  • Independently design and execute experimental strategies using cellular and molecular immunological techniques to investigate target biology and therapeutic mechanisms of action.

  • Develop novel in vitro or ex vivo assays systems to support characterization of novel therapies in in vivo immuno-oncology models.

  • Manage and analyze experimental data and present experimental results at internal meetings and scientific conferences.

  • Establish collaborations with leading academic research groups.

 

Required Experience, Skills, and Education:

  • Ph.D. degree in immunology, cancer biology, cell biology or a related discipline, with 2+ years of post-doctoral or relevant industry experience and demonstrable track record of excellence in tumor immunology and/or immunotherapy.

  • Strong track record of research productivity as evidenced by high-quality, impactful publications, preferably in the field of cancer biology or tumor immunology.

  • Extensive hands on experience in ‘state of the art’ immunology techniques including multi-parameter flow cytometric analyses, cytokine analysis, functional assays, imaging, cell biology and molecular biology.

  • Previous experience with tumor models would be a plus. Knowledge of models that interrogate and modulate cells and mediators of the innate and adaptive immune system would be an advantage.

  • Rigorous, quantitative and detail-oriented experimentalist with a desire to continue in a laboratory-focused role

  • Excellent written and verbal communication skills.

  • Demonstrated ability to multi-task, prioritize options, anticipate challenges, and execute on goals as a member of an interdisciplinary team is extremely important.

  • Thrives in a collaborative team setting and is driven by a desire to deploy innovative approaches and technologies in a high energy start-up environment. 


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Scientific Data Analyst - Informatics

Date Posted:
4/25/2017

Nurix

CA

We are seeking a highly skilled and motivated Scientist to lead and support implementing data assessment and decision systems for biological assays: High-throughput Screening (HTS), in vitro and cellular, in vitro and in vivo ADME and toxicology. This person will establish and support the models and processes used to assess the quality of data, the statistical methods to apply, the criteria for selection of hits, and the capture of decisions why particular methods were selected. This individual will work closely with a team of interdisciplinary scientists and will provide insights to other scientist in order to leverage scientific and information systems to record and drive team decisions. The ideal candidate will be self-driven, resourceful, very organized and focused, and enjoy working in a dynamic team environment.

Primary Functions

  • Understand raw data from low-throughput in vitro and high-throughput screening (HTS) assays
  • Create automated scripts to process assay data into analysis-ready results including consideration to outliers, edge effects, controls, and methods to calculate IC50 and EC50
  • Assist scientists with statistical analysis and interpretation of results into decisions, including pass/fail of target hit, compound confirmation, and activities in counter screens
  • Develop, refine, and deploy models to visualize single and multiple data sets in order to streamline the decision-making process with scientists and leaders
  • Present meaningful, easy-to-understand, consistent visualizations incorporating statistical assessment of data quality with comparisons among methods, data sets, and assay conditions
  • Analyze historical trends across targets and share insight into classes of action and promiscuity
  • Discuss/Document workflow and requirements of scientists into action items
  • Assist in the proper storage and retrieval of information to/from databases

Qualifications

  • Ph.D. in Computational Biology, Computer Science, Bioinformatics, Statistics, or related field with 3+ year’s post-degree experience. Master’s degree candidate with 8+ years’ experience would also be considered.
  • Experience with multivariate statistical techniques, algorithms, and packages to handle systematic and random error in multiple types of biological experiments and implement them in data analysis workflow
  • Knowledge of appropriate models to filter and fit multi-dimensional, chemical and assay data as well as assess the quality of the data being reviewed
  • Expertise in comprehensive data analysis with commercial scripting tools such as Pipeline Pilot and decision tools such as Dotmatics’ Vortex and TIBCO Spotfire
  • Ability to use statistical packages such as R, JMP, Minitab, and ProMV
  • Ability to code algorithms using formal (e.g., Java) or scripting (e.g., Python) languages
  • The successful candidate will be aligned to Nurix’ culture and values; he/she will be team oriented and highly collaborative with a hands-on approach
  • The candidate should be enthusiastic, driven, have the ability to work independently and thrive in a dynamic start-up environment

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Scientist I Affinity Selection, Library Discovery

Date Posted:
4/25/2017

Nurix

CA

Position
We are seeking a highly skilled and motivated Scientist with expertise in protein sciences and affinity selection methodologies to join Nurix’s Library Discovery team. Nurix is devoted to unlocking the therapeutic potential of the ubiquitin proteasome system (UPS) in the areas of oncology and immuno-oncology, by utilizing mechanistic and structural insights to guide drug discovery efforts.

Primary Functions

The successful candidate will utilize DNA encoded libraries to identify novel, physiologically relevant chemical matter for a variety of targets within Nurix’s discovery pipeline. This person will also play a key role in discovery by evolving the standard paradigm of encoded library selection toward more extensive and mechanism-directed selection campaigns that exploit existing biophysical and mutation information. This individual will work closely with an interdisciplinary team of discovery scientists, all of whom have regular opportunities present findings to the project team and senior management. The candidate should have a strong desire to learn new techniques and the ability to incorporate new methodologies into their work. The ideal candidate will be self-driven, resourceful, very organized and focused, and enjoy working in a dynamic team environment.

Qualifications

  • Ph.D. in Biochemistry or related field with 0-3 years post-degree industry experience.
  • Expertise in DNA encoded library affinity selection or related methodologies (phage display or SELEX, etc…).
  • Experience in using biophysical techniques to analyze protein-protein interactions as well as protein-small molecule interactions.
  • Hands on experience performing biochemical assays.
  • Experience with protein expression and purification, ideally with multiprotein complexes.
  • A strong track record (publications or industry experience) with excellent interpersonal skills and ability to work in a team environment.
  • The successful candidate will be aligned to Nurix’s culture and values; he/she will be team oriented and highly collaborative with a hands-on approach.
  • The candidate should be enthusiastic, driven, and have the ability to work independently and thrive in a dynamic start-up environment.

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Scientists Biology

Date Posted:
4/25/2017

Pliant

CA

Description:

Pliant Therapeutics is an early stage biopharmaceutical company focused on the discovery and development of novel therapies for fibrotic diseases. Founded by Third Rock Ventures with world-renowned academic thought leaders, Pliant is raising the bar for progress to meet unmet medical needs for patients and physicians. The company’s focus is on mechanism-based intervention in the fibrotic process using small molecules. The Company is seeking passionate, creative and dedicated scientists to join our team and contribute to our mission.

Position Overview

Immediate openings are available for Scientists/Sr. Scientists with experience in the fibrosis/inflammation area. Experience in cell signaling and previous research industry experience in drug development is a plus. This individual will join a dynamic and growing multidisciplinary team focused on discovery and advancement of new drug candidates and disease biomarkers. The primary responsibility of this position will be related to the field of fibrosis, notably in the discovery of novel signaling pathways.

Responsibilities:

  • Plan and execute experiments related to the evaluation of novel targets and signaling pathways.
  • Make detailed observations, record and analyze data.
  • Troubleshoot experiments.
  • Advance drug discovery programs by interacting with other biologists, chemists and external collaborators.
  • Contribute effectively to patent, report and scientific publication writing.
  • May have the opportunity to manage one or more Research Associates.

Job Requirements:

  • PhD. in Biology/Molecular Biology or equivalent.
  • Minimum of 5-8 years relevant experience in the biotechnology industry strongly preferred.
  • Broad practical experience and knowledge of integrin signaling, pathways leading to cell (epithelial, fibroblast, myofibroblast) activation in fibrotic processes and/or oncology.
  • High level of creativity and productivity with strong problem solving skills.
  • Excellent scientific expertise in fibrosis and/or inflammation conversant with the current literature.
  • Ability to champion the biology efforts into new directions to achieve project milestones.
  • Strong evidence of conceptual thinking, active follow through and vigorous scientific curiosity.
  • Proven ability to work well with others in a dynamic and highly collaborative environment.
  • Exceptional interpersonal, verbal and written communication skills

 


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Scientist Vaccine Immunologist

Date Posted:
4/25/2017

Neon Therapeutics

MA

  • Position Summary

    Neon is seeking a highly-motivated Scientist to join Neon’s Biochemistry group. The candidate will work within the biochemistry group and in close collaboration other groups at Neon on a program that aims to design novel personalized neo-antigen based cancer vaccines. He/she will work independtly as well as part of a multi-disciplinary research team to develop different vaccine technologies.

     

    Job responsibilities include:

    • Expression of recombinant proteins in bacterial cells and protein purification by affinity, ion-exchange, size-exclusion chromatography and protein characterization.
    • Design and molecular cloning of protein constructs and protein engineering.
    • Perform biochemical assays to study protein interactions
    • Participate in the design, development and implementation of cell-based assays.
    • Improvement of current processes and implementation of new technologies.
    • Analysis and presentation of results to larger scientific groups.
    • Work productively in a team environment and independently and deliver against timelines.

     

    Experience and essential skills:

    • PhD in Biochemistry or related biological Science with 0 to 5 years of post-graduate working experience in academia or industry
    • Expert in protein biochemistry and proficiency in various protein purification techniques such as affinity, ion exchange, gel filtration.
    • Strong experience in protein characterization and bioanalytical techniques such as SDS-PAGE, Western blot, ELISA, SEC required.
    • Deep understanding of molecular biology and hands-on-experience in molecular cloning (e.g. Gibson assembly)
    • Knowledge of immunology and dendritic cell biology, and experience in cell culture work.
    • Demonstrated experience in complex problem solving and strong publication record.
    • Excellent organizational, communication skills and a pro-active mentality.
    • Excellent attention to detail.
    • Demonstrated experience functioning within a multi-disciplinary team and utilizing cross-functional information, such as immunology and vaccine development, to optimize the biochemical work flow;
    • Demonstrated experience working with contract research organizations and academic collaborators

     

    Optional Skills:

    Experience with protein bioanalytical methods like SEC-MALS and DLS are beneficial.

     


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Scientist Biochemistry

Date Posted:
4/25/2017

Neon Therapeuitcs

MA

  • Position Summary

    Neon is seeking a highly-motivated Scientist to join Neon’s Biochemistry group. The candidate will work within the biochemistry group and in close collaboration other groups at Neon on a program that aims to design novel personalized neo-antigen based cancer vaccines. He/she will work independtly as well as part of a multi-disciplinary research team to develop different vaccine technologies.

     

    Job responsibilities include:

    • Expression of recombinant proteins in bacterial cells and protein purification by affinity, ion-exchange, size-exclusion chromatography and protein characterization.
    • Design and molecular cloning of protein constructs and protein engineering.
    • Perform biochemical assays to study protein interactions
    • Participate in the design, development and implementation of cell-based assays.
    • Improvement of current processes and implementation of new technologies.
    • Analysis and presentation of results to larger scientific groups.
    • Work productively in a team environment and independently and deliver against timelines.

     

    Experience and essential skills:

    • PhD in Biochemistry or related biological Science with 0 to 5 years of post-graduate working experience in academia or industry
    • Expert in protein biochemistry and proficiency in various protein purification techniques such as affinity, ion exchange, gel filtration.
    • Strong experience in protein characterization and bioanalytical techniques such as SDS-PAGE, Western blot, ELISA, SEC required.
    • Deep understanding of molecular biology and hands-on-experience in molecular cloning (e.g. Gibson assembly)
    • Knowledge of immunology and dendritic cell biology, and experience in cell culture work.
    • Demonstrated experience in complex problem solving and strong publication record.
    • Excellent organizational, communication skills and a pro-active mentality.
    • Excellent attention to detail.
    • Demonstrated experience functioning within a multi-disciplinary team and utilizing cross-functional information, such as immunology and vaccine development, to optimize the biochemical work flow;
    • Demonstrated experience working with contract research organizations and academic collaborators

     

    Optional Skills:

    Experience with protein bioanalytical methods like SEC-MALS and DLS are beneficial.

     


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Scientist/Senior Scientist Pharmacology

Date Posted:
4/25/2017

Constellation

MA

Constellation Pharmaceuticals is a pioneering epigenetics company, focused on the discovery and development of novel, small molecules targeting chromatin regulatory proteins in tumor and immune cells for therapeutic applications in oncology. Our unique discovery platform integrates our understanding of chromatin-regulatory mechanisms with cancer and immune pathways to optimize our drug discovery activities and fully enable the clinical translation of our programs.

We are seeking an experienced, accomplished and resourceful scientist with a successful track record in in vivoand in vitro pharmacology to join our research group. The role involves working closely with the project team leaders to design, execute and evaluate PK-PD and efficacy studies for lead compounds. The ideal candidate will have significant small molecule drug discovery experience in rodent pharmacology as demonstrated by scientific publications/ patents/ high impact projects. The successful applicant will be independent, organized, detail oriented, flexible, and will enjoy working in a dynamic, fast paced team environment.

Key Responsibilities:

  • Independently design, execute and interpret in vivo pharmacology experiments to characterize small molecule based drug pharmacology and mechanism of action to support projects from early discovery to clinical development
  • Manage relationship with external CROs to execute experiments
  • Serve as the pharmacology lead/expert on the project teams and effectively work with others in a highly collaborative, matrixed research environment teams
  • Formulate data-driven decisions by designing and executing experiments that support critical decision making for the program teams
  • Analyze, interpret and communicate data to project teams and senior R&D leadership
  • Additional responsibilities may include, collaborating with biology scientists to establish target engagement assays to support drug discovery
  • Maintain active and timely records of experiments in appropriate databases and e-notebooks and contribute to active dissemination of data
  • Be up-to-date on recent scientific literature and contribute to the understanding of our target space.
  • Attend and present at scientific meetings

Qualifications and Required Experience:

  • Ph.D. in Pharmacology or a related biology discipline, postdoctoral experience and 3-5 years of industry experience.
  • Experience with in vivo model selection, design of PK/PD/ efficacy and drug combination studies.
  • Experience with small molecule based- drug discovery is required.
  • Experience working with CROs and KOLs to conduct in vivo pharmacology experiments is required.
  • Extensive laboratory experience developing and conducting in vitro and in vivo assays.
  • Prior experience with small animal pharmacology (dosing, bleeding, blood/tissue analysis).
  • Proven record of scientific achievements demonstrated by publications and presentations.
  • Excellent oral and written communication skills.
  • Expertise in the area of immuno-oncology and familiarity with syngeneic models a plus.
  • Experience with use of PK and PK/PD modeling and simulation software such as WinNonlin or NONMEM a plus.

 


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Scientist Cancer Immunology

Date Posted:
4/22/2017

Dragonfly Thearpeutics

MA

About Dragonfly
Founded in 2015 by Dr. Tyler Jacks, head of the Koch Institute at MIT, Dr. David Raulet, one of the world's leading experts in Natural Killer (NK) cell biology, and Bill Haney, a longtime tech entrepreneur and investor, Dragonfly Therapeutics develops novel first-in-class therapeutics targeted at Natural Killer cells and other cells of the innate immune system. Our therapies are designed to counterbalance immune suppressive factors present in the tumor microenvironment and mobilize anti-cancer immune responses, and are expected to be potent as single agents as well as in treatment combinations with existing cancer immunotherapies – such as T cell treatments.  Dragonfly’s Scientific Advisory Board and founders are major figures in cancer biology and immunology, and launched Dragonfly to harness the power of the immune system to provide breakthrough cancer treatments for patients. 
 
Scientist, Cancer Immunology
Dragonfly Therapeutics seeks an experienced and motivated Scientist to support the development of new cancer immunotherapies. The Scientist will work with Dragonfly’s team to discover and develop novel biologic drugs that stimulate immune responses against solid and hematologic cancers.
 
Responsibilities:
·         Play a key role in the development of new biologic drugs for cancer immunotherapy
·         Design and execute in vivo pharmacology studies in mice: drug dosing, tumor growth monitoring, blood/TIL/lymphoid tissue isolation and analysis, necropsy, pharmacokinetics, toxicity assessment
·         Purify immune cell subsets, particularly NK cells, from human and mouse blood/tissue samples, and maintain primary cell cultures
·         Develop and perform of cell- and ELISA-based immune assays, immunophenotyping, and IHC/IF
·         Troubleshoot assays and establish standard operating procedures as needed
·         Provide scientific expertise and train/direct others in research techniques
·         Interface and manage external collaborators and CROs as needed
·         Work collaboratively with the Dragonfly team
 
Qualifications:
·         Ph.D. degree in immunology, cancer biology, or relevant field
·         4+ years of relevant research experience, industry experience preferred
·         Strong understanding of immunology and cancer biology
·         Expertise in handling primary T cells or NK/ILC cells from mice and patients/human donors
·         Experience with syngeneic and transplanted tumor models in mice
·         Mastery of cell-based immune assays, flow cytometry, and in vivo techniques for mouse studies
·         Ability to design, effectively communicate, and implement research plans efficiently
·         Excellent written and verbal communication skills and time management skills
·         Ability to work within a team, coordinating with other scientists and leading Research Associates
·         Self-motivated, conscientious, and enthusiastic about curing cancer

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Scientist Target Discovery Group

Date Posted:
4/22/2017

Dana Farber Cancer Center

MA

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

The Belfer Center for Applied Cancer Science is an integrative research center within Dana-Farber Cancer Institute, Harvard Medical School. Our mission is to enhance and accelerate oncology drug discovery & development through bridging of academia, industry and the clinic. We apply industrial capabilities to cutting edge academic/clinical science. We partner with industry in drug discovery/development & work with industrial partners to delineate the clinical path of novel therapies for cancer patients. This integrated goal-oriented organization represents a new academic construct that provides an unprecedented opportunity to change the way anti-cancer therapeutics are discovered and developed

 


									
Requirements

Job Summary

The Belfer Center offers a novel opportunity to participate in the rapidly evolving field of cancer therapeutics for treatment of cancer patients. We seek a highly motivated, collaborative, and scientifically rigorous cancer biologist to join our Center. Working with leading academic clinicians and scientists at a premier cancer institute the successful candidate will do ground breaking work elucidating and developing novel targets for drug discovery. This individual will work with Belfer and Dana Farber scientists to identify next generation cancer targets in several cell autonomous pathways regulating cancer cell growth and in emerging immuno-oncology pathways that enable clinical development strategies for single agent or combination immunotherapies for cancer.

Job Responsibilities

  • Participate in multi-laboratory collaborations to characterize novel drug targets and therapeutic approaches for cancer drug development.
  • Responsible for validating novel oncology targets and biomarkers
  • Delineate the clinical path for novel small molecule inhibitors
  • Responsible for pre-specified deliverables to external industry partners within specified timelines
  • Mentor and manage a group of scientists to deliver innovative results
 

Job Qualifications:

 

  • A Ph.D. in molecular biology, cancer biology, or biological sciences
  • 2-3 years post-doctoral experience
  • Experience in CRISPR genome editing is desired
  • Experience and expertise in flow cytometry is preferred

 

  • Demonstrated scientific excellence & scientific rigor
  • Independent, self-motivated and innovative
  • Strong management and organizational skills
  • Excellent written and oral communication skills
  • Outstanding interpersonal skills
  • Ability to work productively & constructively in a team environment
  • Ability to excel in a goal-oriented, multifaceted and fast-moving team environment
  • Industry experience is a plus

 

 

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.

PI97567561


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Technical Scientific Writer

Date Posted:
4/22/2017

Foundation Medical

MA

Foundation Medicine is a molecular information company focused on fundamentally changing the way in which patients with cancer are treated. Our products provide more than information. They offer hope to patients, their families and friends, their physicians and caregivers.

 

We've seen the difference that our technology can make in the lives of patients, but there is still enormous potential to help even more people. In our drive to help transform the way in which patients with cancer are treated, we strive to improve every life we touch through our dedication to innovation, our commitment to people, and our passion for performance.

 

What makes Foundation Medicine so special?

The cancer treatment paradigm is evolving rapidly and we believe there is now widespread recognition that cancer is a disease of the genome, rather than a disease defined solely by its specific anatomical location in the body. Today, physicians increasingly use precision medicines to target cancers based on the specific genomic alterations driving their growth, but most currently available molecular diagnostic tests only reveal a few of the possible alterations. Foundation Medicine provides truly comprehensive molecular information products that can assess the broadest range of relevant genomic alterations from a patient's tumor and distill this complex molecular information into a concise and actionable format that reveals more treatment options for physicians and their patients.

 

We've seen the difference that our technology can make in the lives of patients, but there is still enormous potential to help even more people. In our drive to help transform the way in which patients with cancer are treated, we strive to improve every life we touch through our dedication to innovation, our commitment to people, and our passion for performance.


									
Requirements

Foundation Medicine is seeking a Scientific and Technical Writer, Regulatory Affairs. This position will assist with Regulatory Affairs activities by writing and editing technical documentation to be included in submissions to the FDA and other regulatory authorities, including the EU. This role will have the unique opportunity to contribute to the development of regulatory submissions in the rapidly growing field of diagnostic next generation sequencing as well as to gain substantial exposure to the scientific and technical aspects of cutting edge technology. The Scientific and Technical Writer will work closely with both Regulatory Affairs, R&D scientists, biostatisticians and software engineers to produce high quality deliverables for regulatory submission. This role will be critical in ensuring that highly technical documentation is concise and understandable to readers that have a relevant scientific background but may not be well versed in the specifics of our technology.

 

Your Impact

As a member of the Regulatory team, you will:

  • Review and edit technical documentation including:
    • Validation Protocols and Reports
    • Software documentation
  • Write and assist in the preparation of FDA submissions including Pre-submission documents, IDE applications, 510(k) applications, premarket notifications/applications and post-market reporting
  • Assist in publishing submissions
 

 

Your Expertise

  • Must have:
    • Strong scientific background in molecular biology
    • Superior technical and scientific writing skills
    • Must be detail oriented with excellent prioritization and organizational skills
    • Ability to deliver results on schedule in a fast-paced, dynamic environment
    • Ability to distill and simplify complex ideas
  • Highly desired:
    • Scientific background in oncology
    • Experience with molecular biology assay validation
    • Experience with regulatory submissions (PMA, IDE, 510(k)
    • PhD preferred with at least 1 years of experience in the pharmaceutical, biotechnology, medical device, or diagnostic industries, or MS with 2+ years of experience as a technical writer.
  • Driven. You will be focused on the achievement of major alliance goals.
  • Solutions focused. Willing to bring creative problem-solving skills to challenges along the way.
  • Scientifically-oriented. You will enjoy learning and being involved in the content of our collaboration activities, and able to converse fluidly with internal and external team members on project goals and activities.
  • Intuitive. You will have a demonstrated ability to work in the “gray zone” and anticipate challenges before they arise.
  • Process-oriented, yet flexible. You will appreciate and be able to create and drive process, and at the same time recognize when rules are meant to be bent.
  • Ability to communicate clearly and concisely with all stakeholders.
  • Independent. You will be able to self-organize and operate effectively without significant day-to-day oversight, while staying tightly connected to key leaders and teams across the collaborations.

PI97570152


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Scientist Computational Biology

Date Posted:
4/22/2017

Commonwealth Sciences

MA

  • Analyze gene editing experiments using next generation sequencing
  • Contribute to CRISPR/ gRNA design for single/ multiple targets
Requirements
  • Ph.D. degree in related discipline
  • NGS experience a must
  • Strong knowledge of UNIX
  • R/ Python statistical language a plus
 

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Postdoc Immunology

Date Posted:
4/22/2017

Syros Pharma

MA

Syros Pharmaceuticals is seeking a dynamic Immunologist to join a team of highly motivated scientists that are using recent fundamental insights into transcriptional regulation to discover and develop novel medicines targeting gene control in cancer, tumor immunology and autoimmunity.

We are an innovative drug discovery company founded in 2012 by leading scientists from the Whitehead Institute and the Dana Farber Cancer Institute with support from top venture firms and a world class Scientific Advisory Board. Combining new insights into gene enhancer function with information from genome-wide profiling, we are pursuing new targets and chemical approaches in an effort to unlock the process of gene control for drug discovery for oncology and autoimmunity.

The Postdoctoral Fellow will participate with project teams in shaping the Autoimmunity research strategy. The motivated individual will be responsible for cell assay development for new target identification and validation for Syros’ discovery and development teams. The successful candidate will have broad subject expertise including Immunology, Cell and Molecular Biology. Expertise in immunological assays including multi-parameter FACS analysis of human and mouse primary cells, cell purification, ELISA, and cell differentiation/proliferation is important. Experience with the culture and activation of primary T and B cells is required. In addition, the candidate should have knowledge in design, execution, and interpretation of  in-vivo studies for validation of potential drug targets in the autoimmunity area. Working knowledge of basic molecular biology techniques such as PCR, cloning, nucleic acid purification and gene transfer technologies (transfection, retroviral transduction) is a plus. Additionally, basic familiarity with next generation sequencing technologies and bioinformatics is desirable.

Responsibilities:

-Provide hands on scientific capabilities in the areas of autoimmunity to both preclinical discovery project and development project teams.

-Deliver critical project data internally and through a network of external study providers. Support Autoimmunity team by providing data to be used in collaborating with leading KOLs.

-Participate in biological selection and in vitro validation of novel drug targets

-Work with team to develop assays to validate drug targets through in vivo proof of concept studies which will include responsibility for study design, monitoring at CRO, data analysis, and interpretation of in vivo study reports.

-Participate in discussions with project team biologists to define the appropriate dose & schedule for novel drug candidates in the chosen in vivo model

- Work with project teams, external collaborators, and CROs, on existing programs and new drug target programs  in the area of autoimmunity

 - Must be flexible and able to contribute to an evolving portfolio of projects spanning early discovery through preclinical stage. 

-Clear communication and presentation skills are a requirement

Requirements

Requirements:

Ph.D. in Immunology or Cell/Molecular Biology or equivalent area with a proven track record of publications in peer reviewed journals.

Must be authorized to work in U.S.

 

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Scientist Structural Biology Biochemistry

Date Posted:
4/22/2017

Fog Pharma

MA

Description

FogPharma is developing breakthrough treatments for patients in serious need through the creation of a powerful new class of medicines, cell-penetrating miniproteins, that target human disease drivers currently considered “undruggable.”  FogPharma is located in Cambridge, MA. 

Job Summary

Our team is seeking a structural biochemist to elucidate the binding and inhibitory mechanisms of novel compounds that target undruggable proteins.

Job Responsibilities 

  • Expression and purification of recombinant target proteins
  • Crystallization, structure determination, and structural analysis of protein-ligand complexes
  • Biochemical characterization of target-ligand binding, with development of new assays as needed
Requirements
  • PhD in biochemistry, chemistry, structural biology, or related field
  • 3+ years relevant post-doctoral or industry experience
  • Extensive experience with protein expression, purification, and characterization; strong working knowledge of Akta purification instruments
  • Extensive experience with all aspects of protein crystallography, including crystallization robotics, data collection, and structure determination
  • Broad experience with in vitro biochemical methods, particularly ligand-binding assays (e.g. pulldowns, SPR/Biacore, FP, FRET, ITC, etc).
  • Deep understanding of biochemistry concepts and literature
  • Aptitude with structural analysis and communication/visualization of findings to team
  • Independence, initiative, focus, willingness to take on responsibility and continually pursue self-improvement
  • Ability to work in a team, communicate, and give/receive constructive feedback
  • High attention to detail, excellent organizational and documentation skills
 

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Senior Scientist Cellular Bioassay

Date Posted:
4/22/2017

TORQUE

MA

Senior Scientist – Cellular Bioassay - TORQUE

TORQUE is focused on developing a whole new category of cell therapies for cancer. The goal is to develop a next generation of immunotherapies to address otherwise intractable cancers – particularly solid tumors. We are a small - yet experienced and well-funded - startup in Kendall Sq, Cambridge.

TORQUE is seeking an independent and highly motivated scientist that will focus on developing functional immune cell assays. The ideal candidate will have industry experience, and a strong background in working with human T-cells and characterizing them by flow cytometry. Familiarity with cell-based assay development for drug potency is a must. Demonstrated examples of previous work in studying protein mechanisms of action, such as receptor binding, receptor activation, cell signaling, internalization and/or subcellular localization in cell-based assays are sought.

Requirements: Ph.D. with 3+ years of experience working in drug development, or MS with 5+ years of experience

Write to: Torque, 450 Kendall St, Cambridge, MA 02142 or email: jobs(at)torque.email

Requirements

Requirements: Ph.D. with 3+ years of experience working in drug development, or MS with 5+ years of experience


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Research Scientist Protein Biochemistry

Date Posted:
4/22/2017

Sciversify

NC

We are seeking an experienced research scientist or associate to join the founding R&D team of a Triangle-based biotechnology company which is developing an innovative clinical diagnostics platform.

In this position, you will be a key member of the company’s assay development team, led by a world-renowned investigator who is widely recognized for pivotal breakthroughs in protein engineering and fluorescent sensor development. You’ll be joining the team on the ground floor as the company drives its cutting-edge diagnostic platform through the discovery phase and into assay optimization, device development, pre-clinical testing, and commercialization. Your overall responsibilities will include:
• Developing and leading one or more collaborative, multi-disciplinary projects focused on specific fluorescent sensor-based diagnostic assays
• Establishing and reporting on project requirements, plans, and accomplishments under the direction of the company’s senior executives
• Ensuring that project milestones are consistently achieved in accordance with expectations from corporate leadership and external investors
• Providing cross-training, expertise, and assistance to other project teams to accelerate assay development and optimize related procedures

You’ll work alongside other exceptional scientists who share your passion for advancing basic research discoveries into the clinical realm. And you will gain valuable experience with the entire translational R&D life cycle of a biotechnology start-up, from both the technical and business perspectives. Your research roles will include:
• Using bioinformatics-based approaches to identify candidate proteins for fluorescent sensor-based clinical diagnostic tests
• Refining and carrying out protocols for the expression, purification, labeling, and characterization of candidate proteins
• Working across teams to develop and optimize procedures for immobilizing fluorescently responsive proteins on solid-state assay substrates
• Maintaining and providing detailed experimental data and other technical inputs to company executives for project management, monitoring, and reporting activities
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Job Requirements


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This position requires a graduate degree in a relevant scientific field (PhD preferred), at least two years of postgraduate experience, and a high degree of competency with advanced protein chemistry and engineering methodologies. The successful candidate will have expertise in protein purification, stability, and ligand binding, as well as a strong understanding of bioinformatics, sequence analysis, and molecular biology concepts. The selected individual will also have:
• Excellent verbal and written communication skills
• Rigorous attention to detail and experimental procedures
• Competency in running software and computer-based tools
• Strong ability to lead and collaborate within and across teams
• Flexibility and adaptability to rapidly changing priorities
• Multi-disciplinary mindset and a drive toward big challenges
• Commitment to advancing clinical diagnostic and care capabilities
• Willingness to go the extra mile for projects and team members

The individual selected for this position will receive a highly competitive compensation package and the opportunity to accrue company stock grants and/or options.

This is an immediate opportunity with the hiring company, and resumes will be reviewed upon submission over the next month. Qualified candidates will be selected for an in-depth interview and evaluation process to ensure that the selected individual will hit the ground running and excel in the position. As part of this process, candidates will be required to provide several professional references and to complete a writing and analysis exercise.

To be eligible for this opportunity, candidates must be legally authorized to work in the United States on a full-time basis and for any employer.

Interested individuals can apply directly at http://careers.sciversify.com.

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Scientist I/II

Date Posted:
4/22/2017

Medimmune

MD

Poisition Description:
MedImmune is the worldwide biologics research and development arm of AstraZeneca. Here, you'll have the opportunity to make a difference in people's lives every day. As one of the world's premier biotechnology companies, our mission is centered on delivering life-changing products that advance world health, and help fight and cure disease. As a Scientist I/II in Gaithersburg, MD, you'll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients' lives.
We're constantly pushing the boundaries of science to deliver life-changing medicines to patients, with a passion for discovery and a pipeline to show for it. We're pioneering innovative research and exploring novel pathways across key therapeutic areas including oncology, respiratory, inflammation and autoimmunity, cardiovascular and metabolic disease, and infection and vaccines. And we're industry-leading in immunology, protein engineering and translational science. We offer a unique and strong collaborative network as part of the AstraZeneca family, as together we explore synergies between small and large molecules.
MedImmune has a dynamic environment that fosters collaboration and innovation. We attract top minds, and we nurture and build top talent.

Responsibilities:
MedImmune is seeking a versatile molecular biologist with virology/immunology experience to explore new technologies relevant to in vivo biologics expression and/or novel pulmonary drug delivery approaches. Potential areas of interest include viral vector based biologics expression platform (e.g. AAV, Ad, RNA viruses), nucleoside-modified RNA antigen expression platforms, and tissue targeted biologics drug delivery (e.g. airway, solid organs). The candidate will be part of a growing cross functional effort to identify novel biologics expression and delivery approaches to combat respiratory disease, and is expected to be creative and innovative in their approach. Supervisory duties may be involved in the future.

Requirements:
This position will be a lab-based, hands-on research position. The appropriate candidate should have strong experience in some of the following areas: molecular cloning, viral vector engineering for gene therapy (AAV experience is plus), nucleotide synthesis and formulation for tissue targeted delivery, protein chemistry, bioconjugation, immunoassays etc.
Strong motivation, attention to detail, ability to conduct high quality research, deal with complex scientific/biologic concepts and ability solve complex problems independently is expected. Must have a proven record to effectively plan and organize work activities and prioritize task completion in a timely fashion. Excellent written, verbal and presentations skills is required
This position will require innovation and an innovative researcher with solid technical skills. The candidate should have demonstrated problem solving skills and versatile research abilities. Prior experience working in the collaboration or in a multidisciplinary matrix environment is desirable.

Experience:
PhD in molecular virology, cell biology, immunology or related scientific discipline with 3+ years of post-degree relevant experience

To Apply:
To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience.

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.


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Senior Scientist in Microbiology

Date Posted:
4/19/2017

Fluid Screen

MA

SENIOR SCIENTIST IN MICROBIOLOGY, MICROFLUIDICS, MICROSCOPY, BIOMEDICAL ENGINEERING

FLUID-SCREEN, INC., CAMBRIDGE, MASSACHUSETTS

Position Description:
Fluid-Screen, Inc. is an award winning Life Sciences startup based in Cambridge, MA. We are commercializing a technology developed at Yale University that can rapidly detect bacterial contamination that can help prevent infectious disease outbreaks and save lives in a variety of settings.
Fluid Screen's lab-on-a-chip system detects bacteria in water, blood and urine with the sensitivity of single bacterium in just 30 minutes, compared to a day or more for alternative technologies. The patented technology and the team have been recognized with the Grand Prize in the Create the Future NASA Design contest (#1 out of 900 entrants worldwide), a Gold Prize in Mass Challenge (top 1% of contenders), and more than ten other awards, the research has been published in Nature.
The company specializes in the development of rapid microbiology solutions for a range of industries including water testing, pharmaceutical manufacturing, and medical diagnostics.
The company is seeking an experienced Senior Scientist to join the team and lead R&D in our Cambridge lab space (LabCentral). The successful candidate will be highly independent, excited to design and execute research activities to develop and test our cutting-edge technology, and willing to expand capabilities in new fields. Do you envision yourself solving some of the world's most important problems? Do you thrive in a high growth, fast paced environment with access to state of the art lab facilities? If so, then this is the opportunity for you.

Experience:

  • Advanced Degree (PhD preferred) in microbiology or biomedical engineering, additional background in medical devices or nanotechnology a plus
  • Experience with optical and fluorescent microscopy
  • Hands-on lab experience with a broad range of methods/technologies/equipment, including: biomedical engineering or microfluidic devices
  • Track record with meticulous bench work and record keeping
  • Ability to focus on the task at hand
  • Strong ability to troubleshoot and problem-solve experiments
  • Experience with BL2 lab practices
  • Proven ability to design and oversee all phases of experiments
  • Comfort handling sensitive materials

Qualities:

  • Independent, self-starter that works well under minimal supervision. You will be responsible for contributing to R&D functions that play a key role on upcoming pilot studies
  • Strong communication. This is a must. It is essential for our team to communicate effectively to deliver complete results
  • Passion for bench work
  • Ambitious with proven leadership track record. This is a high growth opportunity with the potential to help shape the growth of our company
  • Comfortable in fast-paced environments. Must be able to meet deadlines
  • Impact Driven. Fluid-Screen was developed to make a difference in the world
  • Flexible. This is an early stage startup-processes and responsibilities are constantly changing
  • Adaptable. Always willing to help get the job done-no task too big or too small
  • Creative. Your unique thought processes will become key to the success of the company

Culture:
Fluid-Screen is a multi-disciplinary, tight-knit group looking to add another enthusiastic member to our team. We are passionate about our work as we truly believe it will make a difference in the world. This includes taking on responsibilities that may be completely new to you-which should be an exciting opportunity for personal growth!
Interested?

To Apply:
Please include a CV and desired compensation and email: jobs@fluid-screen.com
subject: Senior Scientist (NIH)


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Postdoctoral Affairs Specialist

Date Posted:
4/19/2017

Van Andel Research Institute

MI

POSTDOCTORAL AFFAIRS SPECIALIST

VAN ANDEL RESEARCH INSTITUTE, GRAND RAPIDS, MICHIGAN

Position Description:
Van Andel Research Institute (VARI) is a leading independent biomedical research facility and is dedicated to determining the epigenetic, genetic, molecular and cellular origins of cancer, Parkinson's and other diseases, and translating those findings into effective therapies. The Institute is home to more than 330 scientists and support staff that work in on-site laboratories and in collaborative partnerships that span the globe.
VARI strives to create an environment that stimulates creativity and nurtures professionalism and our Office of Postdoctoral Affairs (OPA) is committed to maintaining the highest standards of postdoctoral training and to provide a program that prepares our postdocs for the next step in their career.

To ensure we are providing our postdoc's the best in research training, we are seeking to hire a Postdoctoral Affairs Specialist to join our OPA team.
As a Postdoctoral Affairs Specialist, your first and foremost responsibility will be to administer and assist in the development of programs, workshops, and professional development opportunities aimed at enhancing the postdoctoral training at VARI.
We also understand winning a competitive fellowship or grant is a mark of distinction in a postdoc's career progression and we encourage our postdoctoral fellows to apply for their own fellowship support during their training at VARI. As the Postdoctoral Affairs Specialist you will also play a role in identifying appropriate funding opportunities and training and writing high quality grant/foundation proposals. These applications will be from government (NIH, NSF, DoD, DTRA, etc.), private grant making foundations, and international sources.

Responsibilities:

Professional and Career Development:

  • Assisting with the planning, developing, and implementing of educational and career training programs for our postdocs.
  • Coordinate workshops, career training events, and professional development opportunities
  • Develop and maintain postdoc resource materials and content to the Office of Postdoctoral Affairs SharePoint site.
  • Assists in the recruitment efforts of postdoctoral fellows through recruiting events, recruitment materials, and networking
  • Administer the postdoc alumni database

Grant Writing and Mentoring:

  • Reviewing literature dealing with grant funds available through government/international agencies and private foundations
  • Working closely with our postdoctoral fellows and their principal investigators on strategizing and identifying appropriate funding opportunities
  • Providing advice/mentorship on policies, guidelines, and practices of relevant funding agencies
  • Facilitating our postdocs, and at times, drafting, and editing proposals
  • Ensuring timely delivery of innovative and approvable grant submissions
  • Assisting in the development of work plans and project timelines for each grant application

Qualifications:
This job might be right for you if:

  • You are motivated and driven. You take ownership of your projects. You like learning new things and advancing your skill set. If you don't know the answer, you'll dig until you find it
  • You love taking on difficult challenges and finding the best solution whether it be tried-and-true or cutting edge
  • You enjoy collaborating and working as a team. You are passionate about building relationships and have a passion for postdoc advocacy and engagement
  • You have a well-established track record of critically contributing to the preparation and able to drive the work of multiple people towards the submission of high quality, competitive grant proposals
  • You are an outstanding writer able to communicate in a compelling and succinct form
  • You have the ability to work well under pressure and perform under tight deadlines

To join our team you need to have at least:

  • A Master's degree (Ph.D. and postdoc experience preferred) in molecular/cellular biology, biochemistry, neurobiology, or other life science.
  • Career and/or professional development training experience
  • Demonstrated ability to identify appropriate scientific funding opportunities.
  • Extensive experience and demonstrated ability to write scientific proposals, publications, reports and presentations.
  • Highly proficient with MS Office and Adobe Acrobat.
  • Ability to work independently and collaboratively with a diverse workforce.

To Apply:
Interested candidates should submit a cover letter and resume as a single combined PDF file here. In your cover letter, please outline your skills and experience in digital integration and communications, your future career goals, and how these factors fit with the position described.

This position will be open until filled. If you have any difficulty uploading your application or any questions, please email Eric Miller at eric.miller@vai.org.

VAI is actively striving to diversify its workforce and strongly encourages qualified individuals from underrepresented groups to apply. Van Andel Institute is an EEO and Affirmative Action Employer.


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Science Officer

Date Posted:
4/19/2017

Ripple Effect Communicatiom

MD

Job description

Job Summary

 

Where Creating the Best Hope for a Healthier Future Begins...

 

Position Summary

 

Plans, supervises, and directs research, investigation, or other technical operations. Provides technical expertise to facilitate the design, implementation, and analysis of procedures, techniques, and results which enables investigators to conduct research projects.

 

Position Key Accountabilities

 

Additional Summary Specific to Job

 

  • Determines feasibility of possible projects to ensure results will have a significant impact. Determines project feasibility in terms of staff, time, and resources.
  • Plans and performs quantitative and qualitative research procedures in various areas of biology, chemistry, physics, and other biomedical, dental, or related scientific areas. Identifies the problem through contact with other researchers, practicing physicians, or literature searches. Formulates a problem or project to research. Designs procedures to solve the problem.
  • Conducts experiments using advanced equipment and applying complex techniques. Procedures may include tissue culture, protein purification, enzyme purification, enzyme assays, membrane protein purification, monoclonal antibody analysis, cytogenic analysis, gel electrophoresis, immunoelectrophoresis, immunofluorescent method, radioimmunoassays, biometry, biofeedback, neurotransmitter analysis, biospectrometry, microtomy, liquid, gas and thin layer chromatography, microspectrophotometry, tissue processing, tissue staining, behavioral testing, anesthetic dosage, neurohistochemistry, animal surgery, immunochemistry, gel electrophoresis, deoxyribonucleic acid (DNA) testing, electron microscopy, and biophysical assays and measurements.
  • Designs experimental procedures, which may involve examining new techniques, that may improve existing analysis and provide additional capabilities.
  • Evaluates the data from the analysis.
  • Presents results in a written paper for publication, in a presentation at a meeting, or through personal contact with faculty members and other researchers.
  • Maintains lab equipment, assists in necessary repairs, and promotes a safe laboratory environment. Ensures direct reports follow safety procedures and attends basic safety training courses.
  • Provides work direction and guidance to personnel within department. May lead projects and activities.
  • Performs other duties as assigned.

     

Organizational Requirements

 

Minimum Education

 

Doctorate Degree.

 

Minimum Experience

 

Two (2) years of experience in a related research environment and have verifiable publications within the field of the research project.

 

Departmental Requirements/Preferences


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Research Scientist

Date Posted:
4/19/2017

University of Texas

TX

Job description

Job Summary

 

Where Creating the Best Hope for a Healthier Future Begins...

 

Position Summary

 

Plans, supervises, and directs research, investigation, or other technical operations. Provides technical expertise to facilitate the design, implementation, and analysis of procedures, techniques, and results which enables investigators to conduct research projects.

 

Position Key Accountabilities

 

Additional Summary Specific to Job

 

  • Determines feasibility of possible projects to ensure results will have a significant impact. Determines project feasibility in terms of staff, time, and resources.
  • Plans and performs quantitative and qualitative research procedures in various areas of biology, chemistry, physics, and other biomedical, dental, or related scientific areas. Identifies the problem through contact with other researchers, practicing physicians, or literature searches. Formulates a problem or project to research. Designs procedures to solve the problem.
  • Conducts experiments using advanced equipment and applying complex techniques. Procedures may include tissue culture, protein purification, enzyme purification, enzyme assays, membrane protein purification, monoclonal antibody analysis, cytogenic analysis, gel electrophoresis, immunoelectrophoresis, immunofluorescent method, radioimmunoassays, biometry, biofeedback, neurotransmitter analysis, biospectrometry, microtomy, liquid, gas and thin layer chromatography, microspectrophotometry, tissue processing, tissue staining, behavioral testing, anesthetic dosage, neurohistochemistry, animal surgery, immunochemistry, gel electrophoresis, deoxyribonucleic acid (DNA) testing, electron microscopy, and biophysical assays and measurements.
  • Designs experimental procedures, which may involve examining new techniques, that may improve existing analysis and provide additional capabilities.
  • Evaluates the data from the analysis.
  • Presents results in a written paper for publication, in a presentation at a meeting, or through personal contact with faculty members and other researchers.
  • Maintains lab equipment, assists in necessary repairs, and promotes a safe laboratory environment. Ensures direct reports follow safety procedures and attends basic safety training courses.
  • Provides work direction and guidance to personnel within department. May lead projects and activities.
  • Performs other duties as assigned.

     

Organizational Requirements

 

Minimum Education

 

Doctorate Degree.

 

Minimum Experience

 

Two (2) years of experience in a related research environment and have verifiable publications within the field of the research project.

 

Departmental Requirements/Preferences


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Scientist Cellular Immunology

Date Posted:
4/19/2017

Bluebird Bio

MA

Join bluebird bio’s enthusiastic and collaborative Cellular Immunotherapy team by contributing to the overall success of our novel gene-based immunotherapy approach. This new Scientist will join our group to design, develop and evaluate novel cellular immunotherapy approaches for clinical applications.

 

 

 

About the job:

  • Work in a team focused on preclinical development of cellular therapeutics
  • Design and develop immunological assays to characterize genetically engineered primary T cells
  • Potential to lead a team of 1-2 research associates
  • Coordinate research projects evaluating strategies to improve efficacy of cellular therapeutics
  • Prepare all technical reports needed in support of an exploratory project moving to process development
  • Exercise independent judgment in development of new methods, techniques and evaluation criteria
  • Effectively interface with other scientific groups in bluebird bio to facilitate the success of projects
  •  

About you:

  • PhD in molecular or cellular immunology
  • 2+ years’ experience beyond PhD as a post-doc in immunology or tumor biology
  • Applied experience in T cell or other immunotherapies
  • Ability to independently design, execute, interpret and communicate experimental results
  • Experience with innovative assay development to assess novel biology
  • Expertise in mammalian cell culture, with specific experience isolating and propagating in vitro culture of human/mouse T lymphocytes
  • Experienced with flow cytometry of primary human cells – cell sorting experience a plus
  • Experienced with immunological assays to assess T cell function
  • Expertise in signaling, innate immunity and cytokine function preferred
  • Expertise in gene editing a plus
  • Experience in working in animal models of adoptive immunotherapy for autoimmune disease or Oncology
  • Proven ability to effectively organize experiments to prosecute research projects studying T cell therapeutics
  • Proven ability to effectively plan and organize work activities and prioritize task completion to meet schedules and deadlines
  • Ability to work as part of a team, collaborating with members of other functional groups
  • Understanding of safe lab practices and BSL requirements
  • Excellent computer skills and experience with Microsoft Excel. Prism, sequence analysis, Flow cytometry data analysis software experience essential
  • “do-what-it-takes” attitude
  • Independently motivated, detail oriented and good problem solving ability
  • Excellent organizational skills, sufficient to multi-task in an extremely fast-paced environment with changing priorities
  • Be ready to embrace the principles of the bluebird bio culture: b colorful, b cooperative, and b yourself

 

Seniority Level

Mid-Senior level

Industry

  • Biotechnology

Employment Type

Full-time

Job Functions

  • Research
  • Science

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Postdoc

Date Posted:
4/19/2017

Cedars Sinai

CA

Job description

Summary Of Essential Job Duties

 

Working independently but in close cooperation and in consultation with the Principal Investigator and other Research Scientists, the Research Fellow candidate will perform routine and complex laboratory procedures throughout the training period. May develop, adapt, and implement new research techniques and protocols. Analyzes and interprets data. May assist in preparation of grant proposals. Participates in publications and presentations as author or co-author. Not responsible for generating grant funds, but strongly encourage to apply for postdoctoral fellowship awards.

 

  • Writes manuscript drafts and presentations as author or co-author.
  • Designs and performs experiments. Will keep appropriate and detailed experimental records/documentation. Analyze results and presents to supervisor.
  • May develop, adapt, and implement new research techniques and protocols, particularly in the area of cancer micro-environment interaction.
  • Analyzes, interprets, summarizes and compiles data for publications.
  • Be able to perform tissue recombination orthotopic xenografting of prostate cancer models.
  • Be able to independantly analyze data and determine the next experimental steps to address a defined hypothesis
  • Be facile with the current literature in tumor biology particularly signal transduction and information dealing with paracrine causes of tumor prgoression

     

Educational Requirements

 

Doctorate (MD, PhD, VMD, or DDS) in area directly related to field of biochemistry, cell biology, or cancer biology. Must have experience in principles and

 

practice of clinical research.

 

Experience

 

Works independently on research projects designed by a mentor (typically the PI) within area of specialization (Breast Medical Oncology). Must have past clinical experience. Must be familiar with clinical research and scientific writing.

 

EEO / AA / F / M / Veteran / Disabled

 

Cedars-Sinai will consider for employment qualified applicants with criminal histories, in accordance with the Los Angeles Fair Chance Initiative for Hiring.

 

Business Entity: CSMC - Cedars-Sinai Medical Center

Seniority Level

Not Applicable

Industry

  • Hospital & Health Care
  • Information Technology and Services
  • Research

Employment Type

Full-time

Job Functions

  • Research
  • Analyst
  • Information Technology

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Sr. Scientist Pain& Symptomatics

Date Posted:
4/19/2017

Merck

PA

Job description

Sr. Scientist, Pain & Symptomatics-BIO004745

 

Description

 

Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. Today, we are building a new kind of healthcare company – one that is ready to help create a healthier future for all of us.

 

Our ability to excel depends on the integrity, knowledge, imagination, skill, diversity and teamwork of an individual like you. To this end, we strive to create an environment of mutual respect, encouragement and teamwork. As part of our global team, you’ll have the opportunity to collaborate with talented and dedicated colleagues while developing and expanding your career.

 

By joining the Neuroscience department at Merck, you will engage in exciting drug discovery research targeting the symptomatic treatment of nervous system disorders including pain, Parkinson’s disease, Alzheimer’s disease, and schizophrenia. We are looking for a technically skilled in vitro scientist, that is motivated to work as part of a high profile team to apply advanced cell biology and electrophysiology techniques to identify, validate, and progress innovative novel drug targets. You will work independently, but will be expected to proactively collaborate with colleagues across disciplines.

 

Primary responsibilities include the design and implementation of in vitro experiments for target identification and mechanism of action studies including establishing in vitro cell-based model systems and performing functional/biochemical cell-based assays to support established discovery programs. The position will also require the ability to study the scientific literature, develop new technical expertise, and be an active participant in scientific dialogue in project meetings and internal/external scientific meetings.

 

Responsibilities Include

 

  • Primary role is to design, execute, interpret and report in vitro experiments.
  • Develop disease relevant cell based models using primary neuronal cells, cell lines, and/or native tissue and execute assays using these preparations.
  • Monitor, review and critically interpret published work to guide internal research.
  • Collaborate with members from other functional areas, including medicinal chemistry, in vivo and in vitro pharmacology and translational sciences.
  • Communicate data clearly and concisely.
  • Interface with external academic, biotechnology, and contract research organizations

     

Education

 

Qualifications

 

  • A Bachelor's degree in Biological or Physical Science with a minimum 7 years of pharmaceutical or biotech industry or academia experience, preferably in neuroscience, OR a Master’s degree in Biological or Physical Science with a minimum 4 years of pharmaceutical or biotech industry or academia experience, OR a Doctoral degree in Biological or Physical Science with a minimum of 1 year of pharmaceutical or biotech industry experience.

     

Required

 

  • Extensive experience with electrophysiology.
  • Primary neuronal cell culture experience.
  • Strong data analysis skills including a practical knowledge of statistics.
  • Demonstrated ability to thrive in a team environment.
  • Established record of innovative thinking to champion new ideas and solve problems.
  • Excellent oral and written communication skills, including preparation of study reports, presentations and ability to contribute to manuscripts for publication in peer reviewed literature.

     

Preferred

 

  • Experience with molecular biology or biochemistry.
  • Experience with calcium imaging and GPCR signaling.
  • Stable cell line generation.
  • Experience developing assays for high throughput screening.
  • Background in transgenic and experimental models of pain, psychiatric, or neurodegenerative diseases.
  • Experience with multiple therapeutic modalities (small molecule, antibody, peptide).
  • Familiarity with human genetics and genetic analysis.

     

Merck is an equal opportunity employer, Minority/Female/Disability/Veteran – proudly embracing diversity in all of its manifestations.

 

Job: Biology-Discovery

 

Job Title:Sr. Scientist, Biology-Discovery

 

Primary Location: NA-US-PA-West Point

 

Employee Status: Regular

 

Travel: Yes, 5 % of the Time

 

Number of Openings: 1

 

Hazardous Materials: Hepatitis ,TB Blood Test

 

Company Trade Name:Merck

Seniority Level

Associate

Industry

  • Staffing and Recruiting

Employment Type

Full-time

Job Functions

  • Research
  • Analyst
  • Information Technology

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Scientist.

Date Posted:
4/19/2017

Pfizer

IL

Job description

 

 

About Pfizer

 

A career at Pfizer offers opportunity, ownership and impact. All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.

 

 

Role Description

 

The scientist will be responsible for supporting clinical release and stability testing for the biologics program within a GMP laboratory. Their focus will be the optimization, qualification, validation, performance and transfer of analytical methods. The scientist will execute these tasks within a matrixed team environment that includes but is not limited to other groups within the Biosimilars Pharmaceutical Sciences Department and other global Pfizer sites as well as third party laboratories and vendors.

 

 

Responsibilities

 

With moderate supervision while demonstrating significant independent ownership of key program tasks, the scientist will: * Execute release and stability testing in support of the biologics program using standard and specialized orthogonal analytical methodologies for proteins/peptides (e.g. liquid chromatography, capillary electrophoresis, SDS-PAGE, UV/Vis, fluorescence, light scattering, mass spectrometry, immunochemical and cell based assays, biophysical characterization techniques) within a GXP laboratory. * Independently design and execute experiments and draw appropriate conclusions from experimental data. * Independently author high-quality technical reports and protocols. * Qualify and/or validate analytical methods to support clinical product testing. * Transfer analytical methods to and from the Biosimilars Pharmaceutical Sciences GMP testing laboratory to support in-process, lot release and stability testing of clinical and/or commercial biologics products * Collaborate with process development and/or formulation development scientists or operations personnel to plan and execute testing to support drug substance/drug product development and/or product manufacturing * Reliably meet project or initiative timelines and revise work plans as needed to address changes in project scope, priorities or timing. * Participate in functional and cross functional teams to promote the advancement of Biosimilars Pharmaceutical Sciences scientifically and in cGMP compliance.

 

 

Qualifications

 

Associates Degree and 12+ years of relevant experience OR B.S. and 6+ years of relevant experience OR M.S. and 3+ years of relevant experience OR Ph.D. and 0+ years of relevant experience. Strong background in standard and specialized methodologies for biologics products. Experience with the qualification/validation of analytical methods for biologic products. Experience in a GMP laboratory. Excellent verbal/written communication skills and the ability to work well in cross functional and/or multi-geography teams. Strong project management and organizational skills. PHYSICAL/MENTAL REQUIREMENTS Ability to perform standard laboratory work (e.g. preparing samples, solutions, performing assays, operating standard laboratory equipment, etc.) and office work (e.g. experimentation documentation, writing/reviewing/approving protocols and reports, performing data analysis, etc.). This will require sitting or standing for several hours at a time and ability to lift up to 40 pounds. NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS This position requires understanding of and adherence to cGMP and Environmental, Health and Safety guidance. Flexibility in schedule may be required for generation and collection of data for experiments with specific time constraints or for conference calls with colleagues in different time zones. Travel may be required but is expected to be less than 5%.

 

 

EEO & Employment Eligibility

 

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.


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Biological Scientist microbiology, molecular biology

Date Posted:
4/19/2017

ASTRIX

NJ

Job description

Biological Scientist

 

Clearance Level Needed: U.S. Citizenship or Green Card Holder required. Individual selected will be subject to a background investigation and must meet eligibility requirements for access to sensitive information.

 

POSITION DESCRIPTION:

  • Performing non-research molecular testing to rapidly identify and characterize potential pathogenic bacterial and viral threat agents.
  • Ensures incoming biological samples are processed and triaged maintaining chain of custody.
  • Performs and interprets a variety of specialized tests and strains, detection, and identification of pathogenic microorganisms.
  • Prepares written and oral reports, answer questions, troubleshoot and make recommendations to the supervisor for inclusion in comprehensive reports on test findings.
  • Maintains and operates equipment including performing calibrations, adjustments, and to operate equipment and instruments properly and in a safe manner.
  • Participates in cross training related to bioterrorism and other public health emergencies.
  • Responsible for maintaining knowledge and skills related to position and program.
  • Expected to properly handle, store, and dispose various biological materials in accordance with safety regulations.
  • Individual must be available 24/7/365 to respond in case of emergency.

 

REQUIRED QUALIFICATIONS:

Should have a Ph.D. or Master’s degree from an accredited university in microbiology, molecular biology or related course work in biological sciences with at least two years of laboratory bench experience, utilizing PCR, aseptic techniques and biological assays, and at least two years of experience serving as a Senior Scientist or Team Leader of a laboratory team/project. Bachelor’s degree from an accredited university requires five years of laboratory bench experience, including at least two years of experience as a Team Leader/Senior Scientist. BSL-3 experience is desirable

 

 

 

 

 

 

We are currently interviewing for this position-Qualified candidates are encourage to apply immediately!

 

Astrix Software Technology, Inc. provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, gender, national origin, age, veteran status, disability, genetic information or testing, family medical leave, sexual orientation, gender identity or expression. Astrix Software Technology, Inc. complies with federal, state and local laws governing employment nondiscrimination in all workplace locations.

 

We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.


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Scientist.

Date Posted:
4/19/2017

Proteos

MI

Job description

Scientist/Senior Scientist I: Protein Purification Group

Proteos is a high-quality contract research organization specializing in expression and purification of recombinant proteins. We are currently seeking a Scientist or Senior Scientist I to join the Protein Purification team.

Functions and Responsibilities

  • Initiates and executes customer sponsored projects independently, following standard operating procedures (SOPs)
  • Contributes to the scientific excellence of Proteos through the continuous production of high quality data
  • Performs additional non-science and/or business related job functions in support of Proteos' strategic business initiatives
  • Remains up to date on the latest biotechnology laboratory techniques and relevant literature.
  • Reports to a Scientific Director

Basic and Preferred Qualifications - Education/Experience

  • PhD or an MS plus 3 years, or a BS plus 6 years of relevant lab experience
  • Comprehensive knowledge of and demonstrated experience with scientific principles/concepts in the areas of
    • protein purification using a variety of chromatographic tools including AKTA FPLC systems
    • purification of recombinant proteins from mammalian, insect and bacterial expression systems
    • purification and analysis of antibodies or antibody fragments
    • protein analysis methods including SDS-PAGE, western blotting, HPLC-SEC, mass spectrometry, AAA, N-terminal sequencing, thermal shift assay, etc.
    • protein activity determination including plate-based enzymatic assays, binding affinity, specifically using ForteBio Octet
    • recombinant protein expression in E. coli
  • Working knowledge of expression in mammalian, insect and bacterial cell lines
  • Team player
  • Ability to work safely in a laboratory environment
  • Ability to work effectively in a fast-paced, team oriented environment
  • Excellent communication skills, both written and verbal

Benefits

  • Competitive salary
  • 401K plan with company match
  • Medical Insurance
  • Paid time off including vacation time, sick time, and 9 company holidays

Requirement

  • Successful applicants will be asked to show proof that they can legally work in the US

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Scientist

Date Posted:
4/19/2017

GeneDx

MD

Job description

This position is a Scientist I role and will be part of the R&D team responsible for developing new technologies and molecular tests for mutation analysis in our CAP/CLIA certified clinical sequencing laboratories. PhD candidates with 1-2 years of experience looking to transition from academia to industry are encouraged to apply.

 

 

Responsibilities will include:

 

  • Lead the invention, development, testing and evaluation of next generation sequencing technologies.
  • Identify bottlenecks and streamline clinical laboratory testing procedures.
  • Design high throughput and scalable next generation sequencing assays for fully automated clinical laboratories.
  • Extensive hands-on use and troubleshooting of Illumina sequencing instruments.
  • Analysis of next generation sequencing data and interpretation of results.
  • Basic shell scripting.

 

Key Skills

 

  • Fundamental understanding of molecular biology techniques and principles.
  • Ability to multitask and prioritize laboratory and data analysis taskas.
  • Strong inter personal skills and the ability to lead the successful completion of experiments.
  • Ability to correlate next generation sequencing data with changes in the laboratory procedure.

 

Requirements:

 

  • PhD in Mol Bio, Biochem, Genetics, or related field.
  • Extensive experience with molecular biology techniques, including sequencing, electrophoresis, cloning.
  • Basic understanding of bioinformatics.
  • Attention to detail and accuracy are critical
  • Ability to work independently and in a team environment.

 

Benefits:

 

  • Health,dental, vision, life insurance Long and short term disability plans

     

  • 401K retirement savings plan with a company match
  • Flexible Spending Account Tuition Assistance, Employee Discounts Paid Time Off Regular performance appraisals, merit increases
  • Work with a company of talented professionals dedicated to making GeneDx shine!
  • Supportive company structure- promoted 100 employees in the last year
  • Business casual environment, dog friendly

 

 

 

Interested candidates must submit an application via GeneDx's online portal at www.genedx.com/apply Requisition 3718BR.

 

 

 

 

 

GeneDx is a VEVRAA Federal Contractor and Equal Employment Opportunity employer.


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Data Scientist

Date Posted:
4/19/2017

Vanda Pharma

DC

Job description

Vanda is seeking a Data Scientist who will primarily be responsible for developing analytical models and providing data driven insights.

 

 

 

Roles and responsibilities include the following:

  • Improve business/scientific decisions across both a broad range of Key Performance Indicators and functions
  • Supports multiple, high impact data research and analysis projects
  • Leverage data / big data to discover patterns and solve strategic analytic business problems using both structured and unstructured data sets across many environments
  • Develop analytic capabilities that drive better outcomes for both customers and the company

Position Requirements

Successful candidates will have the following background/experience:

  • Advanced degree in computer science, mathematics, management science, engineering, operations research, statistics, or related (Master’s degree required, MD or PhD preferred)
  • 2+ years’ experience in data science, advanced analytics, and model building
  • Experience with statistical analysis methods
  • Excellent visualization experience utilizing either Spotfire/Tableau/Clickview and/or custom built solutions
  • Experience with big data manipulation and analysis using varying frameworks/tools: SQL, Python, R, SAS
  • Strong written and verbal communications skills; comfortable communicating with senior levels of both business and technology leadership
  • Experience driving large analytic projects and programs to completion
  • Strong practical knowledge of analytical techniques and methodologies such as machine learning/supervised and unsupervised techniques, segmentation, mix and time series modeling, response modeling, lift modeling, experimental design, neural networks, data mining, Bayesian inference, and optimization techniques
  • Good organizational and communication skills, the ability to work in a collaborative environment, and a desire to improve skills are essential

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Online Neuroscience Community Specialist

Date Posted:
4/14/2017

Society for Neuroscience

DC

Online Neuroscience Community Specialist

The Society for Neuroscience (SfN) is searching for a Community Specialist who will be responsible for the growth of the community and discussion areas of SfN's learning and discussion website, Neuronline.  This role will work with other programmatic departments to help facilitate the growth of smaller communities, along with evolving the strategy and initiatives within our digital community for the benefit of our members. The Specialist must have excellent communication skills, have knowledge of the field, and interest in social media. This would be ideal for a candidate with a science background that has an aptitude for online technology and communication.

ESSENTIAL JOB FUNCTIONS include the following. Other duties may be assigned.

Member Engagement/Online Community Management

  • Coordinate and participate in the development and implementation of strategies to increase member engagement on the Neuronline community and discussion site.
  • Develop and grow SfN programs to encourage member engagement.
  • Serve as a neuroscience subject matter expert to cultivate community for SfN members, and use that neuroscience expertise to seed conversations and connect members with like interests to one another.
  • Cultivate relationships with SfN staff "moderators" (internal SfN staff who manage society programs), helping to grow Neuronline's programmatic communities.
  • Lead monitoring of member engagement on the Neuronline community site, providing regular data, reports, and analysis on member participation and activity.
  • Lead monitoring of member discussions taking place on comment threads and in the forums.
  • Coordinate with staff from other SfN departments to integrate discussion of the SfN annual meeting, The Journal of Neuroscience, eNeuro, and other content into the forums.

Marketing/Communications

  • Lead smooth planning and implementation of Neuronline-related promotional activities and events at the SfN annual meeting in consultation with SfN's communication and marketing departments.
  • Lead the brainstorming for annual meeting and year-round marketing initiatives for Neuronline forums, working closely with communication and marketing departments.

Technology

  • Serve as first responder to any technical problems that arise within the forums, working with the platform vendor and internal technical support staff.
  • Become an expert in the community/discussion software, Discourse.
  • Learn Sitecore, the Content Management System (CMS), to enter content (written articles, video, audio) and set up pages for the Neuronline website.
  • Work in the CMS to review and troubleshoot content prior to it going live on Neuronline.

Content Development

  • Write and edit content and interview scientific experts and members as needed.
  • Draft marketing text to be distributed through SfN's e-newsletter, the SfN website,N communications vehicles

MINIMUM REQUIREMENTS:

Supervisory Experience:

  •  None.

Education and Experience:

  • Bachelor's degree in Neuroscience or other relevant field required; Master's degree or PhD preferred
  • Experience with science communication.
  • Basic understanding of publishing online content, and ability to quickly learn new software; HTML and content management experience preferred
  • Experience facilitating on-line or in-person group discussion

Preferred Qualifications:

  • Excellent oral, written, and interpersonal communication skills.
  • Ability to multitask and set priorities, take initiative, and work within a collaborative team environment.
  • Able to plan and execute tasks, on schedule and with attention to detail.
  • Strongly proficient with Microsoft Office applications, and Internet research.
  • Functional ability in CSS considered a strong asset.
  • Experience working in Content Management Systems considered a strong asset.
  • Ability to learn and master an online community management system.
  • Strong organizational and project management skills with the ability to coordinate a diverse set of activities.

If this is you and you are eager to make meaningful contributions to a highly relevant and important mission, please submit a cover letter with your salary requirements and a copy of your resume for consideration. Applications without cover letters will not be considered.

The Society for Neuroscience is wholly dedicated to recruiting, developing, and retaining a diverse group of talented people.  We are committed to provide equal opportunities to all employees and applicants without regard to race, color, religion, gender, national origin, age, disability, sexual orientation, gender identity, or other protected criteria, in accordance with applicable law and we welcome Veteran applicants.

Our generous benefits package includes:  medical, dental, disability and life insurance; flexible spending accounts, two retirement plans with employer matching and nonmatching contributions; 12 days of paid vacation, 12 days of paid sick leave, with additional personal leave and 10 paid holidays; gym membership reimbursement; and tuition reimbursement.

Apply at https://sfncareers.applicantpro.com/jobs/503896.html . Questions can be directed to Blythe Alexander (blythe.e.alexander@gmail.com). 


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Immunology Scientist I

Date Posted:
4/9/2017

Aeras

MD

Job Description:

The Scientist I is a member of the Human Immunology team, with primary responsibilities in the area of clinical sample logistics and analysis using standard laboratory practices and, when necessary, Good Laboratory Practices or Good Clinical Laboratory Practices.

The Scientist I works under minimal supervision; requires ability to exercise good judgment and discretion in handling assigned responsibilities, including the ability to resolve problems.? Functions are to be completed in a timely manner with acceptable quality.??

Essential Duties and Responsibilities:

Primary Duties and responsibilities shall include, but are not limited to the following:

  • Conducts immunological and general laboratory procedures, using standard laboratory practices, Good Laboratory Practices when appropriate, and Biosafety Level 2 (BSL-2) procedures
  • Works cross-functionally within the Pre-Clinical department to meet organizational objectives
  • Develops, performs, and analyzes data from new immune assays, including expanded flow cytometry panels, ELISpot assays, ELISAs, and other immunological assays
  • Works with collaborators to bring new technology into Aeras as assigned by the Sr. Director of Human Immunology
  • Leads assay validation, QC procedures, and writing, maintenance and updating of laboratory SOPS
  • Ensures the maintenance of complete and clear laboratory notebooks; generates lab progress reports, study protocols, and study reports
  • Presentation of data at internal, national, and international meetings and generates manuscripts for submission to journals
  • Lead cross-functional pre-clinical project development teams as assigned
  • Serve as Immunology representative on assigned product development teams
  • Leads in further development of processes regarding shipping, receiving, recording, storing, and data management of all clinical trial samples
  • Ensures completion of routine laboratory maintenance, including reagent inventory, instrument calibration, and facility monitoring

Qualifications and Requirements:

  • Ph.D. in Immunology or related field with at least two (2) years of experience or a Master?s degree in Immunology or related field with at least five (5) years relevant industry experience
  • Broad background in immunology, including cellular immunology
  • Experience in multi parameter flow cytometry and data analyses, primary human cell culture and PBMC cryo-preservation, and the skills to prepare reports of primary and analyzed data
  • Flexibility in work hours to accommodate cell processing and immunoassay schedules
  • Must maintain a professional demeanor, as well as a pleasant manner and positive ?can-do? attitude while developing and maintaining communications in a cooperative and collaborative manner with all levels across functional teams both internally and externally
  • Flexibility to change priorities and be comfortable with the changing deadlines to meet organization needs when required
  • Must be detail-orientated, with the ability to work on multiple projects while staying on top of them from start to finish and completing projects with acceptable timeliness and quality
  • Highly motivated and a self-starter; demonstrated ability to work independently, as well as in a team while exercising discretion; takes initiative to resolve problems
  • Effective communication (both orally and in writing) and excellent listening skills; strong customer service orientation and interpersonal skills
  • Demonstrated ability to seek, learn and apply new skills/knowledge to perform job responsibilities
  • Follows all company safety practices, Standard Operating Procedures (SOP?s) and policies
  • Excellent computer literacy and ability to learn new software quickly; proficient user of MS Office (Word, Excel, PowerPoint and Outlook) and common business equipment

Preferred Qualifications:

  • Relevant industry experience
  • Experience in characterization and engineering of monoclonal antibodies
  • Experience in qualification/validation of immune assays
  • Training and publication history related to antibody immunology and assay development, such as ELISAs, and BAMA
  • Training and publication history related to human B cell such as B cell ELISpot/FluoroSpot, isotyping, and generation of hybridomas

Location:

Rockville, MD, USA

How to Apply:

Click?HERE?to apply for this position.

Reference code: R10-17

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Associate Editor

Date Posted:
4/9/2017

AAAS

DC

Who We Are

"The advancement of science should be the chief concern of a nation that would conserve and increase the welfare of its people."

-James McKeen Cattell, former AAAS President and Editor of Science

The American Association for the Advancement of Science (AAAS) is an international non-profit organization dedicated to advancing science for the benefit of all people. For over a century, AAAS has been a force for science, from helping to establish science as a credible field in the 19th century to using satellite imaging technology to document human rights abuses in 2007. We are recognized as the world’s largest general scientific society and the proud publisher of the Science family of journals. Past presidents have included astronomer Edward Charles Pickering, anthropologist Margaret Mead, and biologist Stephen Jay Gould. Our mission is centered on the belief that STEM research and education can help solve many of the challenges the world faces today.

AAAS is a culture steeped in history, but adaptive to change and new ideas. We recognize the hard work of our employees and encourage the development of our staff. Our colleagues represent an array of expertise from scholarly publishing to digital marketing, educational research to government relations, all with a shared focus on mission. At AAAS, you are part of a talented team, dedicated to advancing science and serving society.

Work With Us

Science Translational Medicine is seeking a talented scientist or physician scientist interested in biomedical research to join the editorial team in Washington DC, USA or Cambridge, UK. The core responsibility of this role will be to manage the evaluation and review of manuscripts for Science Translational Medicine, an interdisciplinary medical journal established in 2009, which covers translational and clinical research in a range of biomedical fields. 

The Associate Editor position is a full-time position designed for a PhD scientist, MD/PhD physician scientist or MD with research experience. Candidates should have a lively curiosity, excellent communication skills and experience with cutting-edge translational research in genetics/genomics together with one of the following fields: modeling, statistics, big data, precision medicine. Interested candidates must submit a resume and cover letter by April 22, 2017.

Essential Duties and Responsibilities:

  • Manage the evaluation,  review, and editing of submitted manuscripts in one or more of the biomedical fields mentioned above
  • Judge the scientific value of research and select reviewers for submitted manuscripts
  • Discuss and make recommendations regarding manuscripts and reviews with other staff, advisors, authors
  • Write summaries of research results for publication
  • Guide authors on manuscript revisions and edit the manuscripts for scientific content and style before and after revisions
  • Follow manuscripts through the production process to ensure material is published in a timely manner
  • Commission and edit Review, Perspective and Focus articles on a broad range of topics
  • Commission and edit review and opinion content for special issues with the rest of the editorial team
  • Foster relationships and communication with the scientific community through meetings and professional contacts
  • Represent Science Translational Medicine at scientific meetings nationally and internationally.

Key Requirements:

  • Mastery of a professional field typically acquired through completion of a doctoral or medical degree in at least one biomedical or clinical research field
  • 2 to 5 years post PhD or MD experience, including postdoctoral research experience in one or more translational fields and multiple publications
  • Ability to work constructively as a member of a tight-knit dynamic team
  • Comprehensive knowledge of scientific research methods in order to discuss technical issues with authors
  • Exceptional written, communication, and listening skills in order to communicate with authors and reviewers in evaluating, editing and modifying manuscripts
  • Prior scientific editorial experience is not essential but is an advantage. 

Application Process:

Interested candidates should submit a resume and brief cover letter outlining qualifications and interest in the position by April 22, 2017. Up to three writing or other work samples may also be included as separate documents with your application. If we think you might be a good fit for the role, we will contact you with next steps.

AAAS is an EO employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sexual orientation, gender, gender identity, national origin, age, disability, veteran status, or other protected category. AAAS uses E-Verify to confirm the employment eligibility of all newly hired employees.

Learn More:

Visit https://www.aaas.org/ to learn more about what we do

Meet current staff and learn about our office culture on The Muse:

https://www.themuse.com/companies/americanassociationfortheadvancementofscience

Find our latest job opportunities at: https://www.aaas.org/page/employment-aaas

 


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Editing Independent Contractor

Date Posted:
4/9/2017

American Journal Experts

NC

At American Journal Experts (AJE), we help researchers successfully communicate their work through trusted author-oriented solutions to overcome the barriers to the manuscript preparation process. We are actively recruiting independent contractors from a variety of Life Science fields to edit scholarly manuscripts originally written by non-native English speakers so that language is not a barrier to research communication. AJE's independent contract editors work remotely from anywhere with a stable internet connection, can edit within their areas of academic expertise and are compensated based on manuscript length. If editing assignments are made available to the contractor pool, contract editors are under no obligation to accept assignments.

Our current needs are in the following fields:

  • Animal sciences
  • Biochemistry
  • Biomedical engineering
  • Biotechnology and bioengineering
  • Cell biology
  • Cell and tissue engineering
  • Ecology
  • Evolutionary and developmental biology
  • Interdisciplinary biology
  • Microbiology
  • Molecular biology and genetics
  • Neuroscience
  • Paleobiology
  • Zoology and plant sciences
  • Veterinary medicine

To qualify as an independent contract editor, applicants must:


The ideal applicant for this position would have had exposure to life science literature. The candidates who have been most successful in the contract editor role are autonomous, have editing experience and/or strong technical writing skills, and seek to make a positive impact on their field of expertise.


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Scientist I

Date Posted:
4/9/2017

Leidos

MD

Leidos Biomedical Research, Inc. (LBRI), a wholly owned subsidiary of Leidos, operates the Frederick National Laboratory for Cancer Research (FNLCR). FNLCR is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI). It is the only FFRDC dedicated to biomedical research. Through its status as an FFRDC, FNLCR provides NCI and others with a unique national resource to accelerate the development and delivery of effective preventive, diagnostic, and therapeutic products for cancer and AIDS.

 

The breadth of FNLCR’s activities spans the research and development spectrum, including investigator-initiated, hypothesis-driven research into cancer and AIDS; advanced technology programs focused on genetics and genomics, proteins and proteomics, imaging, nanotechnology, bioinformatics, and laboratory animal sciences; clinical operations in support of NCI and National Institute of Allergy and Infectious Diseases (NIAID)-sponsored clinical trials, as well as NCI drug discovery and development efforts; and management and operations of biopharmaceutical development and manufacturing programs under current Good Manufacturing Practice conditions for NCI and NIAID. Administrative, procurement, financial, safety, and facilities support is provided to these R&D activities through state-of-the-art business processes.  LBRI has approximately 1,900 employees and manages an annual operating budget of approximately $450M. 

 

For more information about Leidos Biomedical Research Inc., please visit our webpage at http://www.leidosbiomed.com/


PROGRAM DESCRIPTION

The Strategic Pilots Incubator (SPI) is responsible for the development and management of a portfolio of exploratory projects that are inherently multidisciplinary that impact cancer research and treatment. Projects aim to analyze the complex interactions in tumor cells and tissues and model systems, blending the best of new physics and engineering based advances with established technologies enabling new opportunities for deeper understanding of tumor biology and cancer progression.  Using the latest tools in understanding human performance under stressful conditions can be used to understand and hopefully mitigate the toxic effects of cancer therapy for the patient.

 

JOB DESCRIPTION

This position description does not represent a current opening but may be used to identify candidates with skills and experience for positions within Leidos Biomedical Research that frequently become available. Candidates who express an interest may be considered for future positions at Leidos Biomedical Research

 

We are currently recruiting for an experienced biomedical engineer or scientist to support a newly established High Content Pathology Facility at the Frederick National Laboratory for Cancer Research. The new facility will revolve around tissue and single cell analysis, including circulating tumor cells, with the newly acquired Helios Imaging Mass Cytometer, as well as single cell sequencing.  We are looking for a self-motivated and proactive individual interested in a cutting-edge and developing technology.  The successful candidate will be taking on a pivotal role in the set up and running of the new High Content Pathology Facility.  Subsequent to onsite training, candidates will be expected to be skilled in single cell imaging analysis, CyTOF mass cytometry and to develop and implement different applications of this technology. 

 

The Scientist I will be responsible for:  1) Setting up and technically validating a single cell analysis laboratory at FNLCR, 2) Developing software and macros for running instrumentation, 3) the daily management and operation of the imaging system and CyTOF, 4) establishing standardized operating procedures (SOP), 5) assisting scientists in experimental design and setup, 6) setting up and maintaining an antibody bank and reagent base, and 7) data analysis.

 


Qualifications:
BASIC QUALIFICATIONS

  • Possession of a PhD degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) in Biomedical Science, Physical Science, Engineering, Health Care Informatics or related field or eight (8) years equivalent experience in lieu of degree.
  • Foreign degrees must be evaluated for U.S. equivalency
  • No work experience beyond the doctorate education is required for appointment at this level; however, some candidates may have had one or more years of postdoctoral research and training.
  • Strong bioengineering background with expertise in handling and analyzing large data sets including imaging data, genomic, and digital histopathology
  • Experience in microscopy and image acquisition/analysis
  • Proficiency in R and/or Python programming
  • Proficiency with Microsoft Office including Excel
  • Ability to learn new techniques and troubleshoot assays

PREFERRED QUALIFICATIONS

  • Experience with antibody assay development
  • Prior experience with mass cytometry or flow cytometry
  • Experience with tissue and blood sample handling
  • Advantageous skills: immunocytochemistry (ICC) and immunohistochemistry (IHC) techniques
  • Familiar with usage of a Laboratory Information Management System (LIMS)


Leidos Overview:
Leidos is a global science and technology solutions leader working to solve the world’s toughest challenges in the defense, intelligence, homeland security, civil, and health markets. The company’s 33,000 employees support vital missions for government and commercial customers. Headquartered in Reston, Virginia, Leidos reported pro forma annual revenues of approximately $10 billion for the fiscal year ended January 1, 2016 after giving effect to the recently completed combination of Leidos with Lockheed Martin's Information Systems & Global Solutions business (IS&GS). For more information, visit www.Leidos.com. The company’s diverse employees support vital missions for government and commercial customers. Qualified women, minorities, individuals with disabilities and protected veterans are encouraged to apply. Leidos is an Equal Opportunity Employer.


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Bioinformatics Analsyt

Date Posted:
4/9/2017

Leidos

MD

Leidos Biomedical Research, Inc. (LBRI), a wholly owned subsidiary of Leidos, operates the Frederick National Laboratory for Cancer Research (FNLCR). FNLCR is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI). It is the only FFRDC dedicated to biomedical research. Through its status as an FFRDC, FNLCR provides NCI and others with a unique national resource to accelerate the development and delivery of effective preventive, diagnostic, and therapeutic products for cancer and AIDS.

 

The breadth of FNLCR’s activities spans the research and development spectrum, including investigator-initiated, hypothesis-driven research into cancer and AIDS; advanced technology programs focused on genetics and genomics, proteins and proteomics, imaging, nanotechnology, bioinformatics, and laboratory animal sciences; clinical operations in support of NCI and National Institute of Allergy and Infectious Diseases (NIAID)-sponsored clinical trials, as well as NCI drug discovery and development efforts; and management and operations of biopharmaceutical development and manufacturing programs under current Good Manufacturing Practice conditions for NCI and NIAID. Administrative, procurement, financial, safety, and facilities support is provided to these R&D activities through state-of-the-art business processes.  LBRI has approximately 1,900 employees and manages an annual operating budget of approximately $450M. 

 

For more information about Leidos Biomedical Research Inc., please visit our webpage at https://www.leidos.com/about/companies/leidos-biomedical-research.

 

PROGRAM DESCRIPTION

The Advanced Biomedical Computing Center (ABCC) is a part of the Data Science and Information Technology Program at Leidos Biomedical Research, Inc. The ABCC provides technology development, scientific consultation, collaboration and training, and high-performance computing support to the NCI and NIH scientists and staff. 

 

JOB DESCRIPTION

This position description does not represent a current opening but may be used to identify candidates with skills and experience for positions within Leidos Biomedical Research that frequently become available. Candidates who express an interest may be considered for future positions at Leidos Biomedical Research.

 

The ABCC is seeking Bioinformatics Analyst candidates at all levels to work in the NCI Center for Cancer Research (CCR) Collaborative Research Resource (CCBR). The CCBR provides collaborative bioinformatics support to CCR investigators at the National Cancer Institute (NCI). CCBR bioinformatics analysts are responsible for (i) the analysis and interpretation of high-throughput biomedical data generated by microarray, next-generation sequencing, proteomics and metabolomics platforms (ii) designing, developing and deploying robust workflows, as well as custom scripts, to support the analysis of high-throughput data (iii) mining proprietary and publicly available biological data to generate novel hypotheses or insights and (iv) presenting analysis results, in a clear and concise manner, to scientific audiences. Bioinformatics Analysts are expected to work effectively as a member of a team; coordinate activities among other groups located at the Bethesda, Frederick, Rockville and Gaithersburg NCI campuses; follow sound scientific practices and maintain effective documentation of activities and analyses.  Majority of time will be spent on the main NIH campus in Bethesda.

 


Qualifications:
BASIC QUALIFICATIONS

  • Bachelor’s, Masters or PhD degree in life science/bioinformatics/math/physics/computer related field from an accredited college according to the Council for Higher Education Accreditation (CHEA)  
  • Foreign degrees must be evaluated for U.S. Equivalency.

 

Below are the typical skills we are looking for in candidates:

 

  • Processing high throughput biomedical data: data cleaning, normalization, analysis, interpretation and visualization
  • Data analysis for complex experiments
  • Experience with high throughput analysis pipelines such as, metagenomics, ChIPSeq, RNASeq, ExomeSeq, microarray analysis
  • Experience in using tools for NGS data-processing tools
  • Familiarity with public databases: NCBI, Ensembl, TCGA, cBioPortal, Broad FireHose
  • Knowledge of database programming and working in a cluster environment
  • Ability to work in collaborative environment and contribute to team projects
  • Ability to work without close supervision

Below are the desired skills we are looking for in candidates:

  • Applied statistics and design of experiments
  • Application development experience
  • Experience in submitting data sets to public repositories
  • Management of large genomic data sets including integration with data available from public sources
  • Knowledge of cancer biology
  • Experience with bioinformatics tools such as: Novoalign, STAR, BWA, GATK, Samtools, Annotator, SnpEff, Limma, EdgeR, DESeq2
  • Proficiency in one, preferably two, of the following programming languages: Perl, Python, R, Java and C/C++

This position description does not represent a current opening but may be used to identify candidates with skills and experience for positions within Leidos Biomedical Research that frequently become available. Candidates who express an interest may be considered for future positions at Leidos Biomedical Research


Leidos Overview:
Leidos is a global science and technology solutions leader working to solve the world's toughest challenges in the defense, intelligence, homeland security, civil, and health markets. The company's 33,000 employees support vital missions for government and commercial customers. Headquartered in Reston, Virginia, Leidos reported pro forma annual revenues of approximately $10 billion for the fiscal year ended January 1, 2016 after giving effect to the recently completed combination of Leidos with Lockheed Martin's Information Systems & Global Solutions business (IS&GS). For more information, visit www.Leidos.com. The company's diverse employees support vital missions for government and commercial customers. Qualified women, minorities, individuals with disabilities and protected veterans are encouraged to apply. Leidos is an Equal Opportunity Employer.

Other Locations:  

APPLY NOW    


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Bioinformatics Analsyt

Date Posted:
4/9/2017

Leidos

MD

Leidos Biomedical Research, Inc. (LBRI), a wholly owned subsidiary of Leidos, operates the Frederick National Laboratory for Cancer Research (FNLCR). FNLCR is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI). It is the only FFRDC dedicated to biomedical research. Through its status as an FFRDC, FNLCR provides NCI and others with a unique national resource to accelerate the development and delivery of effective preventive, diagnostic, and therapeutic products for cancer and AIDS.

 

The breadth of FNLCR’s activities spans the research and development spectrum, including investigator-initiated, hypothesis-driven research into cancer and AIDS; advanced technology programs focused on genetics and genomics, proteins and proteomics, imaging, nanotechnology, bioinformatics, and laboratory animal sciences; clinical operations in support of NCI and National Institute of Allergy and Infectious Diseases (NIAID)-sponsored clinical trials, as well as NCI drug discovery and development efforts; and management and operations of biopharmaceutical development and manufacturing programs under current Good Manufacturing Practice conditions for NCI and NIAID. Administrative, procurement, financial, safety, and facilities support is provided to these R&D activities through state-of-the-art business processes.  LBRI has approximately 1,900 employees and manages an annual operating budget of approximately $450M. 

 

For more information about Leidos Biomedical Research Inc., please visit our webpage at https://www.leidos.com/about/companies/leidos-biomedical-research.

 

PROGRAM DESCRIPTION

The Advanced Biomedical Computing Center (ABCC) is a part of the Data Science and Information Technology Program at Leidos Biomedical Research, Inc. The ABCC provides technology development, scientific consultation, collaboration and training, and high-performance computing support to the NCI and NIH scientists and staff. 

 

JOB DESCRIPTION

This position description does not represent a current opening but may be used to identify candidates with skills and experience for positions within Leidos Biomedical Research that frequently become available. Candidates who express an interest may be considered for future positions at Leidos Biomedical Research.

 

The ABCC is seeking Bioinformatics Analyst candidates at all levels to work in the NCI Center for Cancer Research (CCR) Collaborative Research Resource (CCBR). The CCBR provides collaborative bioinformatics support to CCR investigators at the National Cancer Institute (NCI). CCBR bioinformatics analysts are responsible for (i) the analysis and interpretation of high-throughput biomedical data generated by microarray, next-generation sequencing, proteomics and metabolomics platforms (ii) designing, developing and deploying robust workflows, as well as custom scripts, to support the analysis of high-throughput data (iii) mining proprietary and publicly available biological data to generate novel hypotheses or insights and (iv) presenting analysis results, in a clear and concise manner, to scientific audiences. Bioinformatics Analysts are expected to work effectively as a member of a team; coordinate activities among other groups located at the Bethesda, Frederick, Rockville and Gaithersburg NCI campuses; follow sound scientific practices and maintain effective documentation of activities and analyses.  Majority of time will be spent on the main NIH campus in Bethesda.

 


Qualifications:
BASIC QUALIFICATIONS

  • Bachelor’s, Masters or PhD degree in life science/bioinformatics/math/physics/computer related field from an accredited college according to the Council for Higher Education Accreditation (CHEA)  
  • Foreign degrees must be evaluated for U.S. Equivalency.

 

Below are the typical skills we are looking for in candidates:

 

  • Processing high throughput biomedical data: data cleaning, normalization, analysis, interpretation and visualization
  • Data analysis for complex experiments
  • Experience with high throughput analysis pipelines such as, metagenomics, ChIPSeq, RNASeq, ExomeSeq, microarray analysis
  • Experience in using tools for NGS data-processing tools
  • Familiarity with public databases: NCBI, Ensembl, TCGA, cBioPortal, Broad FireHose
  • Knowledge of database programming and working in a cluster environment
  • Ability to work in collaborative environment and contribute to team projects
  • Ability to work without close supervision

Below are the desired skills we are looking for in candidates:

  • Applied statistics and design of experiments
  • Application development experience
  • Experience in submitting data sets to public repositories
  • Management of large genomic data sets including integration with data available from public sources
  • Knowledge of cancer biology
  • Experience with bioinformatics tools such as: Novoalign, STAR, BWA, GATK, Samtools, Annotator, SnpEff, Limma, EdgeR, DESeq2
  • Proficiency in one, preferably two, of the following programming languages: Perl, Python, R, Java and C/C++

This position description does not represent a current opening but may be used to identify candidates with skills and experience for positions within Leidos Biomedical Research that frequently become available. Candidates who express an interest may be considered for future positions at Leidos Biomedical Research


Leidos Overview:
Leidos is a global science and technology solutions leader working to solve the world's toughest challenges in the defense, intelligence, homeland security, civil, and health markets. The company's 33,000 employees support vital missions for government and commercial customers. Headquartered in Reston, Virginia, Leidos reported pro forma annual revenues of approximately $10 billion for the fiscal year ended January 1, 2016 after giving effect to the recently completed combination of Leidos with Lockheed Martin's Information Systems & Global Solutions business (IS&GS). For more information, visit www.Leidos.com. The company's diverse employees support vital missions for government and commercial customers. Qualified women, minorities, individuals with disabilities and protected veterans are encouraged to apply. Leidos is an Equal Opportunity Employer.

Other Locations:  

APPLY NOW    


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Molecular Biology Postdoc

Date Posted:
4/9/2017

Mesa Biotech

CA

Job Description

A motivated and independent molecular biology R&D postdoc scientist is sought to work on
the development of the next generation of molecular nucleic acid disease diagnosis kits. The
ideal candidate will have at a minimum, demonstrated biochemistry and molecular biology
expertise and experience with PCR and Real Time-PCR diagnostic technology. The successful
candidate will design nucleic acid amplification primer and probes for infectious disease
pathogens, develop/optimize molecular diagnostic assays for human infectious diseases and
incorporate the developed assay chemistry into the integrated diagnostic device, validate the
diagnostic device using well-characterized clinical samples. The experience of fluorescencebased
real time PCR measurement, and handling BSL-2 (pathogen) is required. The
successful applicant must work within an integrated multidisciplinary laboratory and be able
to work with other scientists, technicians and students in the team. In addition, the technician
will be expected to interact and work effectively with a demanding, fast-paced biotech startup
environment.

Requirements

Demonstrated experience with PCR, real time PCR methods
• Bioinformatic primer/probe design experience and hand-on experience of PCR assay
development, optimization and clinical validation
• Hands on experience with handling BSL-2 human pathogens
• Experience of clinical sample validation and statistical analysis
• Excellent presentation and written skills
• Excellent team working and communication skill


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Sr. Scientist Medicinal Chemistry

Date Posted:
4/9/2017

BioDuro - Shanghai China

INT

BioDuro, a Bridgewest company, is a leading life sciences research organization that provides biopharmaceutical clients with comprehensive, integrated drug discovery services spanning from target identification through Phase 0.  With depth and breadth of therapeutic expertise in small molecule discovery, and large molecular development and scale up, combined with unique technology platforms, BioDuro is well positioned to help clients significantly accelerate their lead discovery programs.
With its headquarters located in San Diego, California, the company was established in Beijing in 2005. It opened its branches and drug discovery center in Shanghai and Nanjing in 2012 and 2013 respectively. BioDuro’s global operations include a total of nearly 600 employees in Santiago, Beijing, Shanghai and Nanjing. It has a 100,000 sf facility in Beijing, a 92,000 sf state of the art facility in Shanghai, and a team of highly experienced research staff and scientists, of whom 20% own Phd degree and 15% overseas background.  
With the highest concentration of drug discovery expertise of any contract research organization (CRO) in China and a broad range of capabilities in chemistry, discovery biology, drug metabolism and pharmacokinetics (DMPK), pharmacology, as well as integrated preclinical research and development services, BioDuro brings superior insight and innovative solutions to its clients’ drug discovery programs. Through a strategic partnership with X-Chem Inc., BioDuro is able to conduct innovative hit and lead generation by using its proprietary DNA-based chemical libraries, giving the clients access to large, diverse libraries of compounds that can be used to better interrogate a broad range of high priority drug targets, which can significantly accelerate lead discovery and improve the probability of success.
The Bridgewest Group (BBG) is a closely held investment company with global assets in the biotech and hi-tech industries. With its managed fund of more than 1.5 billion USD, BBG creates long-term value through the application of superior industry knowledge, operational expertise and significant financial resources to attractive investment opportunities. The subsidiary companies of BBG also include monoclonal antibody technique platform companies, biotech companies and pharmaceutical preparation and manufacturing companies such as Formex, BioAtla, Femta, Molecular Response, etc. Among them, Formex is a leading contract development and manufacturing organization. In July, 2015, Formex merged with BioDuro, which extended BioDuro’s new drug discovery service from pre-clinical stage to clinical field. Under the leadership of BBG, BioDuro will continue to improve its core competitiveness, expand and enhance its services and cultivate its employees to increase their research and development ability, aiming at becoming the best international drug discovery and service company of the industry.

BioDuro (Shanghai)

BioDuro (Shanghai) is a wholly-owned subsidiary of BioDuro, located at the Waigaoqiao Free Trade Zone. Same as its parent company, BioDuro (Shanghai) focuses on providing new drug discovery service. The company houses pharmaceutical chemistry, DMPK, and integrated biology and pharmacology as well as an operational team. It owns a 7,200 square meters state of the art laboratory and a 2,000 square meters office building. The 2,000 square meters laboratory for animal experiment has been approved by the AAALAC. Currently, the company has more than 150 employees and is growing rapidly.


________________________________________        
Senior Scientist in Chemistry  ?????????    

(Location: Shanghai)

Key activities: As a key member of a high performance chemistry team in BioDuro's R&D center located in Shanghai, China, you will be responsible for independently developing and optimizing synthetic routes toward synthesis of novel compounds in mg to multi-g scales.

Requirements

Requirements:
•   Ph.D. in synthetic organic chemistry with a strong scientific track record
•   Excellent problem solver
•   Be able to deliver under a tight timeline
•   Medicinal chemistry experience a plus

*candidates must have experience working in the US

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Scientist I DMPK

Date Posted:
4/9/2017

Abbvie

CA

Job Description

Pharmacyclics, an AbbVie Company, based in Sunnyvale, CA represents the single largest acquisition AbbVie has ever made, and is key to AbbVie’s corporate strategy to add another very significant growth platform and diversification. Pharmacyclics will be run as a semi-autonomous, fully integrated operating unit of AbbVie, with all functions including among others Commercial, R&D and Manufacturing. The integration into AbbVie should be minimally disruptive for Pharmacyclics; hence the identity, structures and relative independence will be minimally adapted at this time. The new President of Pharmacyclics is Erik von Borcke, currently a senior executive with AbbVie who has relocated to the Sunnyvale Area and reports to the Chairman and CEO of AbbVie, Rick Gonzalez.

The DMPK department at Pharmacyclics, Sunnyvale, CA is seeking a motivated Scientist to join the Metabolite Identification group. The responsibilities include profiling and characterization of metabolites (small molecules) from biological matrices and related ADME assays. A background in delineating biotransformation pathways and structural elucidation by LC-MS is preferred. Work closely with bioanalytical and PK scientists to integrate drug metabolism data for drug discovery and ADME data for lead optimization.  Experience with in vivo preclinical and ADME assays and understanding of clearance route, mechanism and the role of metabolism is preferred.

Key Accountabilities/Core Job Responsibilities:

   Ability to learn quickly and execute laboratory techniques essential for in vitro ADME analysis (TDI, CYP inhibition, reaction phenotyping) for lead optimization in drug discovery
   Proficiency in LC-MS method development for separation and structural identification of multiple metabolites from various matrices
   Good understanding of organic/structural elucidation chemistry, xenobiotic and extra hepatic metabolism
   Hands on experience in operation, maintenance & trouble shooting of LC-MS instruments of multiple vendors (Sciex/Thermo) and associated software’s
   Conduct in vitro drug metabolism studies, to quantify test compounds and their metabolites in various matrices including microsomes, S9 preparation, hepatocytes and in vivo PK samples
   Conduct non-radio-labeled and radio-labeled metabolite profiling experiments from in vitro and in vivo studies
   Maintain accurate records and write in vitro ADME reports for in-house studies

Requirements



   PhD degree (1-3 years) B.S. or MS degree (5-7 years) equivalent in drug metabolism or related discipline with relevant industrial experience in drug discovery/development

   Prior experience with HPLC and LC-MS are required. Familiarity with AB Sciex and/or Thermo Orbitrap high resolution mass spectrometry instruments are a must
   Experience in utilizing radio-labeled material would be preferred
   The candidate must be able to analyze data and maintain detailed, accurate and comprehensible study documentation. Experience with various scientific data base is a plus
   The individual is also expected to be organized, a team player, enthusiastic about drug discovery, and possess strong communication skills

Equal Opportunity Employer Minorities/Women/Veterans/Disabled


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Senior Principle Scientist - Cancer Immunology

Date Posted:
4/9/2017

Pfizer

CA

A career at Pfizer offers opportunity, ownership and impact. All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.



Role Description

The Cancer Vaccines & Immunotherapeutics group seeks to discover novel cancer vaccines and oncolytic viruses using a variety of technology platforms in combination with immunomodulatory agents. We are searching for a motivated individual with in-depth immunoassay experience and a prior track record in the field of oncology (preferably immuno-oncology), to join our Immunology group in San Diego, California. This position will require the successful applicant to perform the role of a line manager, overseeing and mentoring other scientists in the Cancer Immunology group, maintain an oversight presence in the laboratory as a matrix team leader charged with directly ensuring high-quality data is delivered in an organized and safe manner.



Responsibilities

The candidate will be required to: * Develop and guide strategies that advance the development of vaccine-based and oncolytic virus-based cancer immunotherapies by applying immunological knowledge to circumvent tumor microenvironment-mediated suppression of anti-tumor immune responses.
* Contribute scientific knowledge, innovation, and strategic thinking as a core member on project leadership teams by being fully accountable for the progress and success of the project whether acting as a line representative or project lead.
* Provide broad expertise in T cell immunology including the development and consistent application of immunoassays (e.g. ELISpot, flow cytometry, T cell cytotoxicity, multiplex cytokine analysis) to measure vaccine-induced cellular responses.
* Proactively apply scientific knowledge to the design of in-vivo studies that effectively answer experimental questions with high-value to project progression.
* Manage several direct reports, with responsibility for their day-to-day workload and professional development, and organize and oversee efforts of larger teams in a matrix environment.
* Apply exceptional organizational skills to overseeing the scheduling of study readouts, confirming personnel and resources are available to run required immunoassays, and ensuring all colleagues participating know their roles and responsibilities.
* Oversee rigorous QC of data and endorse study result interpretations prior to release to project teams. Responsibilities: Laboratory work (~20% of time) and other efforts will be performed with minimal supervision: * Define study aims and experimental plans with project teams and both initiate and oversee work within functional line.
* Coordinate scheduling of study readouts with project team members and Immunopharmacology line representatives.
* Organize and oversee immunoassay teams on study readouts, coordinating both the laboratory work and the generation of data in a timely fashion.
* Manage day-to-day workload of several direct reports ensuring they deliver on their goals.
* Build capacity/functionality of the Cellular Immunology team by ensuring the latest methodologies and technologies are considered and adopted as applicable.
* Analyze and interpret experimental data and subsequently present findings at appropriate project team, departmental and leadership meeting settings. Communication: * Actively contributes ideas and challenges data at Immunology line and project team meetings.
* Provides clear, concise and timely responses to project team requests for data and experimental information. Documentation: * Authorship of SOPs, study reports and protocols
* Regular entry of experimental plans and laboratory notes into an electronic notebook system in compliance with corporate policies
* Preparation of PowerPoint-based slides for presentation to project teams and senior leadership Safety: * Complies with all EH&S regulations and safe laboratory practices and is a vigilant advocate for the safety of fellow colleagues.
* Identifies and acts to reduce hazards and risks in the laboratory through use of Risk Assessments and Job-based Hazard Assessments.

Requirements

Qualifications

Qualifications: * PhD in life sciences, with a strong focus on immunology and/or immuno-oncology.
* 7+ years' experience working in a relevant laboratory setting that routinely performs cellular immunoassays to characterize immune responses. Preferred: * Prior work experience primarily based in biotech/pharmaceutical industry settings and focused around areas of cellular immunology and/or immuno-oncology.
* Research experience applying immune checkpoint inhibitor strategies to various disease areas.
* Extensive practical experience with handling/processing animal lymphoid tissues/blood and human blood samples, flow cytometry (>6-color staining) acquisition and analysis, ELISpot, multiplex cytokine (MSD, Luminex), T cell cytotoxicity, and proliferation based assays.
* Experience with high-throughput sample automation systems and developing/implementing new assays. Physical/Mental Requirements: Due to the applicant to be able to function and operate in a research laboratory; involving sitting, standing, walking, bending, ability to perform mathematical calculations and ability to perform complex data analysis. The applicant will be required to work with BSL2 infectious viruses, e.g. Vaccinia virus, adenovirus, influenza, and must receive and maintain required vaccinations or provide satisfactory proof of same. Travel and Environment Requirements: Applicant will need to travel to external research laboratories if and when required, often traveling out of normal business hours. Applicant will have to adhere to safe work practices and procedures such as aseptic laboratory practices and infectious agent handling precautions. Organizational Relationships: Will have regular interaction with project teams and other Vaccine Immunotherapeutics lines, e.g. Immunopharmacology, Formulations & Analytics, Protein and Viral Sciences. Supervision: Applicant will be required to manage several direct reports, and in addition, a matrix group of colleagues.



EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.


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Computational Biologist

Date Posted:
4/9/2017

Pfizer

MA

About Pfizer

A career at Pfizer offers opportunity, ownership and impact. All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.



Role Description

The availability both of ever-larger datasets of gene expression and function and of quantitative markers of disease, combined with emerging information about the genetic bases of human disease, offers new opportunities for science-based drug discovery across disease areas. Pfizer is capitalizing on this emerging science with a computational group focused on target identification and validation. The Senior Computational Target Validation Scientist will be accountable to and will work closely with the biologists in one or more specific disease areas analyzing in-house and public RNAseq, NGS and other 'omics data types to evaluate the biological rationale of existing drug programs and to prioritize potential new drug targets. The Senior Computational Target Validation Scientist will work with members of the human genetics group to integrate human genetics evidence of gene-disease association into computational target identification and validation efforts. The Senior Computational Target Validation Scientist will work together with members of the computational biomedicine group to integrate the clinical and real-world perspectives, as well as to leverage a broader suite of computational capabilities and analytical tools, in bringing forward targets, disease hypotheses and pathways for further biological and functional validation, and in providing foundational information that informs precision medicine strategies. The Senior Computational Target Validation Scientist position offers an opportunity to execute science-based drug discovery within one of the world's leading developers of human therapeutics, at the Pfizer Biomedical Institute based in the Cambridge Innovation Hub.



Responsibilities

Lead a coordinating interface with the biologists and project teams in a specific disease area to drive comprehensive computational target identification and validation. Be accountable to and work with senior Research Unit personnel to ensure strategic and functional alignment around target identification and validation needs and activities; to identify opportunities where novel, innovative approaches or technologies could be applied to advance critical Research Unit goals; and to champion proposals that translate strategy into action. Deliver computational analyses of high-dimensional datasets such as RNAseq, NGS or metabolomics from model systems, disease systems, and, molecular profiling databases to understand disease biology, potential drug targets and specific genetic variants. Integrate multiple levels of biological information to inform protein-disease networks in the context of drug discovery. Provide hypotheses and insights based on complex multidimensional data analyses to inform and aid in design of biological validation studies initiated by RU for functional validation (e.g., siRNA, CRISPR/Cas9). Identify novel data sources, computational methods, and external collaborations that will grow capabilities in computational target validation. Lead internal/external collaborations that secure access to innovative computational methodologies and/or relevant datasets to advance our ability to understand disease pathophysiology from large-scale molecular and phenotypic data. Manage direct matrix computational resources to achieve goals on disease area projects, drawing on the broader skillsets of colleagues within Human Genetics, Computational Biology & Biomedicine, Biostatistics and the Research Units themselves to support comprehensive target validation through advanced data analysis and data integration.

Requirements

Qualifications

Ph.D. in Computational Biology, Biological Sciences, Bioinformatics, Computer Science, Applied Mathematics or other natural science required; 7+ years relevant experience applying quantitative approaches to solving biological problems, preferably in a pharmaceutical, biotech or comparable context. Curiosity about biological and pathological processes and mechanisms Strong background in human biology/medicine, with some knowledge of disease pathophysiology for Immunology and Inflammation, Neuroscience or Neurodegeneration or Rare Diseases highly preferred. Proficiency in multiple programming, scripting, querying or statistical analysis languages including R, python, perl, SQL. Demonstrated expertise in design, execution and interpretation of in vivo and in vitro biological experiments, especially RNAseq or other NGS. Demonstrated expertise in delivering insights and hypotheses from complex multi-dimensional biological data in a biomedical context. Demonstrated experience applying computational approaches to deliver insights and hypotheses, e.g., multivariate, Bayesian and machine learning approaches. Pharmaceutically relevant experience or formal training in computational biology, bioinformatics, computer science or medicine. Demonstrated ability for sound experimental design for in-silico experimentation/workflows required, in addition to ability to effectively interface with Research Unit biologist to communicate/discuss results, ideas, and follow-up experiments. In depth knowledge of relevant public and proprietary databases, methods and tools. Demonstrated experience leading limited duration cross-disciplinary teams to achieve specific goals. Excellent communication skills (oral and written) as demonstrated by publications & presentations. Excellent performance management and talent development skills. PHYSICAL/MENTAL REQUIREMENTS Primarily sitting at a desk and moving through offices. Light travel load. No extra-ordinary requirements. Ability to perform complex data analysis Ability to learn new areas of disease biology Ability to learn and use new computational techniques and tools



EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.


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Computational Biologist

Date Posted:
4/9/2017

Pfizer

MA

About Pfizer

A career at Pfizer offers opportunity, ownership and impact. All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.



Role Description

The availability both of ever-larger datasets of gene expression and function and of quantitative markers of disease, combined with emerging information about the genetic bases of human disease, offers new opportunities for science-based drug discovery across disease areas. Pfizer is capitalizing on this emerging science with a computational group focused on target identification and validation. The Senior Computational Target Validation Scientist will be accountable to and will work closely with the biologists in one or more specific disease areas analyzing in-house and public RNAseq, NGS and other 'omics data types to evaluate the biological rationale of existing drug programs and to prioritize potential new drug targets. The Senior Computational Target Validation Scientist will work with members of the human genetics group to integrate human genetics evidence of gene-disease association into computational target identification and validation efforts. The Senior Computational Target Validation Scientist will work together with members of the computational biomedicine group to integrate the clinical and real-world perspectives, as well as to leverage a broader suite of computational capabilities and analytical tools, in bringing forward targets, disease hypotheses and pathways for further biological and functional validation, and in providing foundational information that informs precision medicine strategies. The Senior Computational Target Validation Scientist position offers an opportunity to execute science-based drug discovery within one of the world's leading developers of human therapeutics, at the Pfizer Biomedical Institute based in the Cambridge Innovation Hub.



Responsibilities

Lead a coordinating interface with the biologists and project teams in a specific disease area to drive comprehensive computational target identification and validation. Be accountable to and work with senior Research Unit personnel to ensure strategic and functional alignment around target identification and validation needs and activities; to identify opportunities where novel, innovative approaches or technologies could be applied to advance critical Research Unit goals; and to champion proposals that translate strategy into action. Deliver computational analyses of high-dimensional datasets such as RNAseq, NGS or metabolomics from model systems, disease systems, and, molecular profiling databases to understand disease biology, potential drug targets and specific genetic variants. Integrate multiple levels of biological information to inform protein-disease networks in the context of drug discovery. Provide hypotheses and insights based on complex multidimensional data analyses to inform and aid in design of biological validation studies initiated by RU for functional validation (e.g., siRNA, CRISPR/Cas9). Identify novel data sources, computational methods, and external collaborations that will grow capabilities in computational target validation. Lead internal/external collaborations that secure access to innovative computational methodologies and/or relevant datasets to advance our ability to understand disease pathophysiology from large-scale molecular and phenotypic data. Manage direct matrix computational resources to achieve goals on disease area projects, drawing on the broader skillsets of colleagues within Human Genetics, Computational Biology & Biomedicine, Biostatistics and the Research Units themselves to support comprehensive target validation through advanced data analysis and data integration.

Requirements

Qualifications

Ph.D. in Computational Biology, Biological Sciences, Bioinformatics, Computer Science, Applied Mathematics or other natural science required; 7+ years relevant experience applying quantitative approaches to solving biological problems, preferably in a pharmaceutical, biotech or comparable context. Curiosity about biological and pathological processes and mechanisms Strong background in human biology/medicine, with some knowledge of disease pathophysiology for Immunology and Inflammation, Neuroscience or Neurodegeneration or Rare Diseases highly preferred. Proficiency in multiple programming, scripting, querying or statistical analysis languages including R, python, perl, SQL. Demonstrated expertise in design, execution and interpretation of in vivo and in vitro biological experiments, especially RNAseq or other NGS. Demonstrated expertise in delivering insights and hypotheses from complex multi-dimensional biological data in a biomedical context. Demonstrated experience applying computational approaches to deliver insights and hypotheses, e.g., multivariate, Bayesian and machine learning approaches. Pharmaceutically relevant experience or formal training in computational biology, bioinformatics, computer science or medicine. Demonstrated ability for sound experimental design for in-silico experimentation/workflows required, in addition to ability to effectively interface with Research Unit biologist to communicate/discuss results, ideas, and follow-up experiments. In depth knowledge of relevant public and proprietary databases, methods and tools. Demonstrated experience leading limited duration cross-disciplinary teams to achieve specific goals. Excellent communication skills (oral and written) as demonstrated by publications & presentations. Excellent performance management and talent development skills. PHYSICAL/MENTAL REQUIREMENTS Primarily sitting at a desk and moving through offices. Light travel load. No extra-ordinary requirements. Ability to perform complex data analysis Ability to learn new areas of disease biology Ability to learn and use new computational techniques and tools



EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.


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Scientist Antibody Discovery

Date Posted:
4/9/2017

Amgen

INT

Job Details Location: 7990 Enterprise Street Burnaby BC, Canada V5A1V7

Salary $85,000.00 to $115,000.00 annually for 37.5 hours per week

1 Vacancy

Terms of employment Permanent

Full-Time 3 weeks vacation medical/dental/life insurance retirement plan long term incentive (stock)

Start date As soon as possible Contact:  

Role: Scientist - Therapeutic Antibody Discovery and Characterization Location: Burnaby BC

Amgen is a leading global biotechnology company, with a mission to serve patients around the world. As a science-based, patient-focused organization, we discover and develop innovative therapies to treat serious illnesses. Our medicines have made a dramatic difference in the lives of millions.

Amgen British Columbia, located in Metro Vancouver, Canada, is a research center of excellence focused primarily on the use of XenoMouse® technology for the discovery of fully human therapeutic monoclonal antibodies. This team is seeking a highly motivated and experienced researcher to help us advance our therapeutic antibody discovery efforts.

The incumbent will complement an innovative group with a strong track record of success in pioneering novel antibody-based therapeutics to treat grievous illnesses. The role will be laboratory-based, supporting multiple diverse therapeutic discovery programs, in addition, to bringing forward crucial new concepts and techniques to identify therapeutic candidates with extreme functional design goals.

An essential part of this role is a demonstrated competency with in vitro selection technologies such as Phage display, Yeast display or Mammalian display with fundamental scientific strengths in protein biochemistry, molecular biology and cell biology. This role will also be involved in assay development and design, scientific analysis, problem solving and creativity. Canadian and international applicants will be considered.

 

Requirements

Basic Qualifications PhD in a scientific discipline OR Master's degree in a scientific discipline and 4 years of scientific experience OR Bachelor's degree in a scientific discipline and 6 years of scientific experience

 

  • 2+ years' experience in one or more antibody discovery technologies (e.g. hybridoma, phage display, B cell recovery (SLAM), nanoscale screening, gel microdrop, NGS, etc.)
  • Assay development supporting large molecule screening

Preferred Qualifications Knowledge of FACS based binding assays and analysis 3+ years' relevant post-doctoral research or equivalent industry experience in therapeutic antibody discovery field. Proficiency in screening characterization platforms; Biacore, ForteBio, etc. Large molecule discovery and development experience Demonstrated Group management/leadership experience Experience in a working environment requiring strong inter-personal and communication skills across a broad range of audiences including senior scientists and leaders throughout an organization A consistent record of scientific achievement including innovation, collaboration and publication. Experience in a role requiring strong problem solving and scientific skills IP creation

Amgen endeavors to make its recruitment process accessible to any and all users. Reasonable accommodations will be provided, upon request, to applicants with disabilities in order to facilitate equal opportunity throughout the recruitment and selection process. Please contact  to make a request and ensure you include the requisition number.

Reasonable accommodations are available, upon request, to facilitate the equal participation of candidates with disabilities, should you be selected for an interview.

 


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Flow Cytometry Specialist

Date Posted:
4/9/2017

Miltenyyi Biotec

GA

Have you always been motivated by your passion for sales and a desire to foster lasting relationships with science partners? If yes, join our team as a…

Flow Cytometry Specialist
South

Your tasks
As a member of the Miltenyi Biotec North America Sales Team, you will be responsible for our flow instruments throughout a Southern territory based in Houston or Atlanta. You will use your instrument sales acumen, flow cytometry knowledge, and technical skills to acquire new customers from biotechnology companies, academic research institutions, and pharmaceutical companies, while simultaneously augmenting existing customer relationships. In addition, you will go above and beyond by analyzing the market for new product opportunities and acting as a knowledgeable resource for customers who have questions or product-related issues. Your outgoing nature and ability to gain buy-in from others will help Miltenyi Biotec showcase itself successfully and professionally, and as a result grow the sales of the company overall.

Requirements

Your profile
•   You have a B.S., M.S., or Ph. D. degree in life sciences
•   You desire more than the typical 9am-5pm job
•   You have 2+ years of hands-on experience with flow cytometers
•   You have 1+ years of experience in a field-based role within the life sciences industry
•   You have exceptionally impressive organizational skills
•   You possess the instincts of a hunter, which will easily translate into you successfully finding new sales leads
•   Strong communication and presentation skills help you to persuade others, which is one of your greatest strengths
•   Frequent travel fits your lifestyle

Miltenyi Biotec is expanding and evolving. Our culture is one that empowers you to embrace new challenges and influence change. Join a fresh and collaborative working environment that encourages contribution, innovation, and growth.

We empower great science. For more than 25 years, Miltenyi Biotec has provided innovative tools, instruments, and solutions that advance biomedical research and cellular therapy. We are 1,800 scientists, engineers, physicians, support specialists, marketers, and more – all dedicated to improving scientific understanding and impacting human lives. At our headquarters campus and offices worldwide, fresh ideas become unique products.

Miltenyi Biotec is an EO Employer – M/F/Veteran/Disability


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Biomedical Writer

Date Posted:
4/9/2017

Palladian

MD

Palladian Partners, an Altarum Institute company, seeks a full-time biomedical science/health writer to work at our Silver Spring, MD headquarters. Palladian Partners is a creative communications firm dedicated to disseminating information about new discoveries in health, medicine, and social science to professionals, educators, patients, families, and the public. In this position, you will interact with all levels of staff and use your outstanding editorial and organizational skills on a wide range of print and web projects in support of high-profile clients.

 

To be considered for this position, you must be equally adept at writing for scientific audiences about the use of zinc finger nucleases in HIV research as you are at writing for the general public about stroke risk factors.

 

Responsibilities:

  • Conduct research and write web content about a wide range of biomedical research and public health topics
  • Interview scientists and thought leaders at major research institutions nationwide
  • Contribute to social media and video communications projects
  • Write and edit web content, journal articles, news releases, fact sheets, and infographic content
  • Attend scientific conferences and summarize proceedings
  • Work directly with clients and collaborate with other staff members
 

Qualifications:

  • Advanced degree in a life science
  • Five+ years of science writing and editing experience
  • Ability to translate very technical scientific content into lively prose for lay audiences
  • Strong understanding of the difference between writing for print and the web
  • Ability to work under pressure and deliver outstanding web and print content on deadline
  • Outstanding customer service skills

You’ll Earn Bonus Points if You Have Experience

  • Writing about cardiovascular, respiratory, and sleep topics
  • Producing social media content
  • Writing and editing for low-literacy audiences
  • Writing video scripts and speeches
  • Attending and writing summaries of scientific meetings
  • Writing and editing journal articles
  • Working in a government contracting environment
  • Supervising and mentoring other writers

 

Palladian employees are highly talented and are encouraged to think and work creatively and strive for excellence. Palladian offers competitive pay, excellent benefits, and the satisfaction that comes from working on interesting, meaningful projects every day. Palladian’s dynamic work environment emphasizes integrity, personal commitment, and teamwork. We invite you to explore exciting and rewarding career opportunities with us.

 

Palladian Partners is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to, among other things, race, color, religion, sex, sexual orientation, gender identity, national origin, age, status as a protected veteran, or disability.

 
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Senior Scientist

Date Posted:
4/9/2017

BD

MD

Job Description Summary

Becton Dickinson is a world leader in pathogen identification and antimicrobial susceptibility testing in the clinical microbiology laboratory. We are currently seeking a high-potential individual with microbiology skills who can work independently and within a multifunctional team to contribute to the development of automated diagnostics solutions for the evolving clinical microbiology laboratory. The successful candidate will be an innovative biologist/microbiologist or biomedical engineer with a relevant life sciences background and demonstrated experience solving complex biological problems. The successful candidate will be able to effectively transition between manipulating biologicals, consumables and mechanical platforms. Candidates for this lab-based position will have excellent skills in the design, execution, data analysis and interpretation, and presentation of laboratory experiments with minimal supervision and demonstrated learning agility. They will have excellent interpersonal and communication skills and enjoy working in a team environment. A basic understanding of product development, particularly in a regulated clinical environment is desirable.

Job Description

Primary Duties and Responsibilities:

The successful candidate will work within the R&D microbiology team to conceive, develop, integrate and test diagnostic capabilities as part of an integrated automated platform for use in a clinical microbiology lab.

In a team environment, she/he will work in the areas of specimen processing, pathogen detection, isolation, identification, and antimicrobial susceptibility testing of microorganisms, with responsiblities for the design and execution of experiments, maintaining technical data, data analysis and  interpretation, and generating reports.  She/he will be required to communicate information and ideas clearly and effectively within a multi-disciplinary group at various levels of the business.

The primary responsibilities include:

  • Provides technical leadership and domain expertise in microbiology to cross-functional project teams aimed at the development of novel infectious disease diagnostics. Works closely with other functions (i.e., Marketing, Operations, Quality, Engineering R&D) to troubleshoot, characterize and resolve needs in existing and nacent technologies.
  • With minimal oversight, delivers hands-on lab-based experimental contributions toward programs or business objectives. Is highly learning agile, innovative and organized: proficient in executing multiple, simultaneous projects in a time-efficient manner. Independently provides data analysis and interpretation.
  • Maintains substantial current knowledge in relevant state-of-the art principles and technologies in clinical microbiology, microbial physiology, biochemistry and data analysis methods. Exercises and contributes to intellectual property and the scientific literature.
  • Collaboratively performs testing on prototype instruments and executes subsequent formal validations.
  • Develops protocols and experimental procedures to address issues or evaluate potential designs.  Writes reports, specification or documents related to these efforts.
  • Prepares procedures, write technical reports, publishes research papers, and makes recommendations based on their research findings
  • Identifies clinical microbiology needs, and innovates novel concepts, approaches, and solutions for addressing those needs
  • Engages in collaborative efforts with academic, hospital and other external organizations. May have responsibility for managing third-party relationships.
  • May have personnel management responsibilities.

Required Education and Experience:

  • A minimum of a Bachelor’s degree in an appropriate field with at least 5 years of relevant Microbiology experience.
  • MS or PhD preferred. 
  • The successful candidate will have a demonstrated aptitude for solving problems involving biological and instrumented platforms.
  • Experience with data storage, processing and analysis is desirable.

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Senior Associate (Neuroscience), Health and Medical Philanthropy

Date Posted:
4/6/2017

Milken Institute Center for Strategic Philanthropy

DC

About the Center for Strategic Philanthropy
Charitable giving in America has consistently been on the rise, exceeding more than $300 billion. Furthermore, high net worth philanthropists are increasingly moving away from passive giving approaches towards more active approaches, with the intent of enhancing the impact of their investments. Such approaches include evaluation of the landscape to set a giving strategy that addresses key unmet needs, monitoring their investments, and consulting with advisors to help structure and deploy their gifts.

The Milken Institute Center for Strategic Philanthropy (CSP), houses a number of programs, including a philanthropy advisory service that uniquely positions the center to improve the ROI of philanthropic capital by facilitating more strategic, informed, and creative philanthropic investment. To execute this work across key issue areas, we recruit technical experts in a number of fields including biomedical research, education, public health, etc.

As a result of the development of deep technical expertise among our team, CSP programs are grounded in robust analysis and expert input, creates a marketplace of innovative giving practices, forges greater awareness of high-impact investment opportunities, and connects ideas with action and capital in order to tackle some of the world’s most pressing social challenges.

About the Milken Institute
The Milken Institute is a globally engaged, publicly supported, non-partisan, nonprofit think tank with offices in Santa Monica, California, Washington, D.C. and Singapore. Its mission is to improve lives around the world by advancing innovative economic and policy solutions that create jobs, widen access to capital and enhance health. The Milken Institute offers an excellent benefit package including medical/dental, LTD

Position Description:

The Senior Associate will serve as the technical lead on neuroscience related philanthropy engagements as well as others. These engagements include the state of the science analysis, assembly and support of scientific advisory groups, facilitation of scientific retreats, and the development of disease specific Giving Smarter Guides – which provides comprehensive, digestible information that helps philanthropists and foundations evaluate research efforts and funding opportunities in relationship to the state of the science and key unmet needs in the field. Additionally, the Senior Associate will work with the CSP team to expand the Philanthropist Toolkit by developing resources that will inform giving strategies and gift evaluation. 

A successful candidate will able to:

  • Support due diligence efforts for neuroscience and other diseases in our portfolio which include but are not limited to oncology, rare disease, inflammatory disorders, etc.
  • Lead key portions of analysis of selected diseases, including development of landscape of experimental therapies, industry pipelines, key research players, etc.;
  • Support activities of a disease-specific scientific advisory board, including coordinating meetings, preparing materials, conducting specific analysis as requested, etc.;
  • Represent the Milken Institute within the broader biomedical research community throughout the due diligence process and at various industry-specific events; and
  • Develop executive-level literature to communicate findings for philanthropists, researchers, advisors, etc.
  • Contribute to communications efforts to building awareness of key funding opportunities, philanthropy resources, and overall opportunities to engage with the center and CSP
  • Support the expansion of the Philanthropy Toolkit to include investment decision-making tools and case studies of innovative philanthropy strategies and giving vehicles

Requirements

  • Scientific and/or medical training / education required, graduate level degree highly preferred;
  • Scientific writing experience for both technical and lay audiences;
  • High intellectual capacity that can be and has been applied to learning new areas of science and technology and related fields;
  • Facility in navigating scientific literature, scientific conferences, clinical trials data, and other medical research resources;
  • Familiarity with research administration, grant evaluation, and/or innovative philanthropy funding models is a plus;
  • Personal attitude that includes being outgoing, entrepreneurial, action-oriented, flexible, with a willingness to adapt to changing situations and have a good sense of humor; and
  • Excellent verbal and written communication skills.

Requirements to Apply

Please click HERE, to access the submission web form to submit your cover letter (required) and resume for consideration for this position.
You can also apply by accessing the Milken Institute Careers page: http://www.milkeninstitute.org/about/careers 


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Scientist Drug delivery and biomaterials

Date Posted:
4/1/2017

Allergan

CA

Allergan plc (NYSE: AGN) is a bold, global pharmaceutical company and a leader in a new industry model – Growth Pharma.  Allergan is focused on developing, manufacturing and commercializing branded pharmaceuticals and biologic products for patients around the world.
 
Allergan markets a portfolio of best-in-class products that provide novel treatments for the central nervous system, eye care, medical aesthetics and dermatology, gastroenterology, women's health, urology, anti-infective and cardiovascular therapeutic categories. With commercial operations in approximately 100 countries, Allergan is committed to working with physicians, healthcare providers and patients to deliver innovative and meaningful treatments that help people around the world live longer, healthier lives.
 
Our success is powered by our world-class team’s commitment to being Bold for Life. Together, we build bridges, power ideas, act fast and drive results for our customers and patients around the world by always doing what it is right.
 
Join one of the world’s fastest growing pharmaceutical companies!
 
At Allergan you will have the opportunity to thrive in a fast-paced, strategic environment where bold, innovative thinking isn’t just welcomed, it’s encouraged. Across all functions, we relish the opportunity to help our people fulfill their potential. Our rapid growth strategy means plenty of opportunities to step into the spotlight.
 
Position Description
 
The Scientist, Drug Delivery & Biomaterials plans, directs, and executes dermal research formulation and drug delivery system development to support nonclinical studies and clinical trials for dermatological and aesthetic indications. A key element of this position is the development of novel dosage forms for enhancing, targeting or sustaining dermal delivery of small and large drug molecules. This incumbent will provide scientific and technical leadership for the development of topical research formulations and the evaluation of dermal drug delivery technologies within Global Pharmaceutical Sciences.
 
Main Areas of Responsibilities
  • Demonstrates strong lab skills in preparing and characterizing topical formulations, designing and conducting skin permeation studies, and applying and developing various analytical methods.
  • Demonstrates scientific excellence through scientific reports, published articles in peer-reviewed journals, society participation, regulatory filings, and/ or patents.
  • Applies current CMC regulatory requirements and guidance to support global registration of new products.
  • Represents department at project team meetings and works closely with other research groups such as Pharmacology, Pharmacokinetics, and Toxicology as well as CMC related departments such as Pharmaceutical Sciences, Process Chemistry, Regulatory Affairs, Quality, Clinical Development and Marketing to meet project timelines and objectives.
  • Exhibits leadership skills that result in good performance and career development of junior staff.
Requirements
 
The following listed requirements need to be met at a minimum level to be considered for the job: 
  • Hands-on experience with semi-solid/suspension dosage forms, e.g. topical formulations including gels, creams, and patches
  • Analytical method development and analysis using HPLC and ELISA
  • Ability to function as a CMC team leader and utilize knowledge of pharmaceutical science, chemical engineering, literature and experience to guide decisions in complex situations.
  • May require <10% travel.  
Preferred Skills/Qualifications
 
The below skills are attributes that may not be mandatory, but are definitely desired in the ideal candidate. 
  • Experience with physical and chemical stability, including potency, rheological property, and particle size measurements
  • Patents in the area of specialization and scientific publications in areas of specialization
  • Knowledge of fundamental applications of statistics 
Education 
  • Ph.D. level education, preferably in the pharmaceutical sciences with 2 years specific related experience OR; M.S. with 4+ years of industrial experience.

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Scientist Microbiology

Date Posted:
4/1/2017

Allergan

CA

Allergan plc (NYSE: AGN) is a bold, global pharmaceutical company and a leader in a new industry model – Growth Pharma.  Allergan is focused on developing, manufacturing and commercializing branded pharmaceuticals and biologic products for patients around the world.
 
Allergan markets a portfolio of best-in-class products that provide novel treatments for the central nervous system, eye care, medical aesthetics and dermatology, gastroenterology, women's health, urology, anti-infective and cardiovascular therapeutic categories. With commercial operations in approximately 100 countries, Allergan is committed to working with physicians, healthcare providers and patients to deliver innovative and meaningful treatments that help people around the world live longer, healthier lives.
 
Our success is powered by our world-class team’s commitment to being Bold for Life. Together, we build bridges, power ideas, act fast and drive results for our customers and patients around the world by always doing what it is right.
 
Join one of the world’s fastest growing pharmaceutical companies!
 
At Allergan you will have the opportunity to thrive in a fast-paced, strategic environment where bold, innovative thinking isn’t just welcomed, it’s encouraged. Across all functions, we relish the opportunity to help our people fulfill their potential. Our rapid growth strategy means plenty of opportunities to step into the spotlight.
 
Position Description
 
The Scientist, Microbiology - Pharmaceutical Development performs microbiological testing in a cGMP environment and manages the testing at contract labs.  He/she records and reports data for evaluating the efficacy and safety of all microbiological attributes for ophthalmic, dermatological, and parenteral products, for both small molecule drugs and biologics, and their raw materials.  He/she validates microbiological methods in preparation for testing.  He/she writes SOPs and conducts investigations to address deviations and OOS/OOT data through QMS.
 
 
Requirements
 
The following listed requirements need to be met at a minimum level to be considered for the job:
  • Must demonstrate a good knowledge of microbiological theories, concepts and principles.
  • Experience with a wide range of microbiological techniques including handling of bacterial and fungal cultures, aseptic procedures, and microbiology-related experimentation
  • Sound knowledge of aseptic manufacturing processes and sterility testing
  • Familiarity with the operation of standard microbiology equipment such as microscopes, spectrophotometers, pH meters, autoclaves, biohazard safety hoods and isolators.
  • Demonstrated ability to manage projects, implement continuous improvement, and make risk-based decisions
  • Must possess good interpersonal skills, the ability to work in a dynamic team environment and be able to multi-task to meet project timelines. 

 

Preferred Skills/Qualifications
 
The below skills are attributes that may not be mandatory, but are definitely desired in the ideal candidate.
  • Experience with other pharmaceutical microbiology attributes such as preservative effectiveness, microbial limits, bioburden and endotoxin is highly desirable
  • Some supervisory experience will be considered a plus
 
Education
  • M.S. degree in Microbiology or related life sciences with five (5) or more years of experience in pharmaceutical microbiology in a cGMP setting OR
  • B.S. degree in Microbiology or related life sciences with seven (7) or more years of experience in pharmaceutical microbiology in a cGMP setting OR
  • Ph.D. degree in Microbiology with two (2) years of work experience may be considered

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Associate Medical Science Liaison

Date Posted:
4/1/2017

Allergan

MD

Allergan plc (NYSE: AGN) is a bold, global pharmaceutical company and a leader in a new industry model – Growth Pharma.  Allergan is focused on developing, manufacturing and commercializing branded pharmaceuticals and biologic products for patients around the world. Allergan markets a portfolio of best-in-class products that provide novel treatments for the central nervous system, eye care, medical aesthetics and dermatology, gastroenterology, women's health, urology, anti-infective and cardiovascular therapeutic categories. With commercial operations in approximately 100 countries, Allergan is committed to working with physicians, healthcare providers and patients to deliver innovative and meaningful treatments that help people around the world live longer, healthier lives.  Our success is powered by our world-class team’s commitment to being Bold for Life. Together, we build bridges, power ideas, act fast and drive results for our customers and patients around the world by always doing what it is right.
                                                                                                                                                    
Join one of the world’s fastest growing pharmaceutical companies!
 
At Allergan you will have the opportunity to thrive in a fast-paced, strategic environment where bold, innovative thinking isn’t just welcomed, it’s encouraged. Across all functions, we relish the opportunity to help our people fulfill their potential. Our rapid growth strategy means plenty of opportunities to step into the spotlight.
 
Position Description
 
Develops and maintains professional relationships with internal and external customers to provide comprehensive medical and scientific support to Allergan initiatives in assigned therapeutic areas. 
 
Facilitates information, education, and research activities for physicians and ancillary healthcare professionals regarding current and future therapies in development or commercialized by Allergan. Works closely with other Allergan personnel to ensure information, education, and research needs of healthcare professionals are met and to ensure scientific and technical training needs of commercial organizations are identified and met
 
Responsible for maintaining annual expenses within assigned budget parameters
 
Responsible for accurate and timely documentation of above activities
The employee must conduct their work activities in compliance with all Allergan internal requirements and with all applicable regulatory requirements.  Allergan internal requirements include compliance with ethics, environmental health and safety, financial, human resources, and general business policies, requirements and objectives.
 
1.             Identify, develop and maintain professional relationships with thought leaders, academic centers and researchers in assigned areas of therapeutic interest to ensure access to current medical and scientific information on Allergan products. 
2.             Upon request, present data on Allergan products to healthcare professionals including physicians, academic institutions, researchers, and other health care professionals. 
3.             Support research initiatives as requested by Allergan R&D, Clinical Operations, and Medical Affairs Departments.
4.             Serve as internal medical and scientific resource to assigned Allergan therapeutic areas for development of disease-state and product communications and materials that are medically accurate, balanced, and consistent with regulatory guidelines.
5.             Support Round Table and Advisory Board sessions to ensure accuracy of scientific and clinical data.
6.             Conducts on-going training to medical affairs, field sales and other internal personnel as directed. 
 
7.             May provide support for payer-facing activities to public and commercial managed markets
Education and Experience
 
         Advanced degree with health science background (Pharm.D, M.D., Ph.D, preferred)
 
·         Preferred minimum 3 year total specific industry experience (pharma, device, etc) and minimum 4 years post professional degree practice or relevant transferable experience (clinical practice, academic research, regulatory/scientific)
 
·         Experience in Urology preferred
 
  Essential Skills and Abilities
 
·         Knowledge of applicable pharmaceutical industry legal and regulatory guidelines
 
·         Proficiency in Excel, Word, Power Point and other software skills

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Scientist I

Date Posted:
4/1/2017

Pacira

NJ

At Pacira Pharmaceuticals, controlling postsurgical pain is the key to improving patient outcomes.  Our in-depth knowledge of the needs of the postsurgical pain market, coupled with our passion for delivering improved patient care, drives our commitment to providing solutions that address unmet medical needs and improve clinical results.  We currently have an opportunity for a Scientist I-Research and Development, in our San Diego, CA offices.

The Scientist I will develop new analytical methods and technical assistance for development projects and support commercial product manufacture.    

Responsibilities:
• Develop and evaluate (qualify/validate) new analytical methods.   
• Design, execute and interpret experimental results.     
• Summarize findings for internal distribution/presentation.  Summarize findings in presentations, technical reports, and manuscripts for external distribution and/or presentation.   
• Write documents for regulatory submissions and/or review (e.g. IND’s, NDA’s, SOP’s, STM’s, batch records, qualification and validation protocols and reports).
• Represent department at project team meetings. 
• Maintain good working knowledge of the use, maintenance and repair of laboratory and manufacturing equipment.  
• Comply with cGMP’s where appropriate.

Qualifications:
• PhD in relevant field (e.g. Analytical Chemistry, Physical Chemistry, Pharmacy), or BS degree with 12 years of combined academic and pharmaceutical experience.
• Extensive knowledge of analytical techniques utilized in Pharmaceutical and Biotech industries. 
• Good understanding of the chemical and physical principals upon which formulation, process development and analytical methodology is based.
• Proficient in using typical laboratory and processing equipment such as:  HPLC, UV Spec, pH meter.
• Proficient in the use of computers and MS Office applications. 

We encourage candidates who meet these requirements to submit a cover letter and resume/CV. Pacira Pharmaceuticals offers excellent compensation and benefits package that includes Medical/Dental/Vision plans, life insurance, 401(K), short and long term disability and paid time off. 
 
Pacira Pharmaceuticals, Inc. is committed to leveraging the talent of a diverse workforce to create great opportunities for our business and our people. EEO Employer: AA/Disables/Vet/Sexual Orientation/Gender Identity
 

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Program Manager

Date Posted:
4/1/2017

Akebia

MA

Job Description

Program Management is an ever increasingly important function within any Pharmaceutical organization. It is the key support element driving forward projects, portfolios and products which make innovation happen. Furthermore, it serves as the cornerstone by which Senior Leadership are able to collaborate and bridge communication to the development teams in support of product innovation in order to drive the business strategy across multiple functions.

As Akebia grows, the Program Management organization will play a key role in leading and operationalizing the projects across the organization. This is a crucial organization within Akebia’s organization and must be steadfast to constantly challenge the organization and constantly strive to be a strategic and innovative group. This requires a constant focus on the delivery of the “new and better” all the while being flexible enough to accommodate any unexpected new developments during the process.

Required Skills

The R&D Project Manager will be responsible for the management of key projects within the Research group.  This individual will work closely with the research group members to develop and implement robust research plans and strategies, tracking progress against plans and program goals, and foster effective communication across all internal stakeholders.   The ideal candidate will have a strong scientific background and extensive experience with discovery-stage research and pre-clinical development.   The successful candidate will have experience managing cross-functional program teams.  The role also requires the ability to identify and communicate business risk to stakeholders and identify mitigation strategies.

Manage cross-functional discovery/pre-clinical stage program teams with the scientific Lead or Program Lead in conjunction with the Global Program Team to ensure the development of robust strategies, integrated plans, scenarios, and risk mitigation

  • Provide leadership, coordination, and cross-functional communication to enable the team to meet the program goals
  • Meet with stakeholders, coordinate consensus, prepare plan, obtain management approval; provide the required liaison of projects managing internal, external and third party relationships
  • Identify and track the discovery/pre-clinical path for assigned projects
  • Budgeting: identify the project resource allocation and external expenses
  • Schedule and conduct regular project meetings as well as periodic project reviews
  • Assist in risk mitigation and communication to management and key stakeholders
  • Create and maintain comprehensive project documentation (e.g. Minutes, Dashboards)
  • Develop comprehensive, integrated recommendations and operational program plans to achieve scientific objectives and corporate goals for pipeline growth.
  • Facilitate internal decision-making processes and provide regular updates to senior management.
  • Implement program management tools and templates to facilitate effective planning and communication (planning agendas, scheduling meetings, preparing minutes, and following-up with team members on critical action items)
Required Experience
  • BS degree in life sciences or a related field is required.
  • MS or PhD in life science or a related field is preferred.
  • A minimum of 5 years of research project management experience in biotechnology, pharmaceuticals, or medical research.
  • Research experience and discovery/ pre-clinical stage drug development is required.
  • Experience managing external vendors, CROs, collaborators and consultants.
  • Strong understanding and competency in planning processes and decision making
  • Strong problem solving skills and an attention to detail
  • Strong presentation skills for both internal and external audiences
  • Highly motivated and a strong team player with the ability to handle multiple priorities in a fast-paced environment
  • Strong analytical and technology skills, including proficiency in project planning and, content management tools, and the Microsoft Office Suite
  • Budget building and tracking skills
  • Ability to influence without direct authority
  • PMP Certification a plus.
Job Location
Cambridge, Massachusetts, United States
Position Type
Full-Time/Regular
 

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Associate

Date Posted:
4/1/2017

Amzak Health

NY

Associate, Amzak Health

Amzak Health, a healthcare investment company based in New York City, is seeking an Associate to join our team.  Amzak Health has permanent investment capital and invests across the healthcare sector including therapeutics, devices, diagnostics and services.  We invest in both private and public companies that are developing products that are both clinically important and commercially attractive.  Our investment professionals take an active role in our portfolio companies.

The Associate will play an important role in generation of new investment opportunities, conducting due diligence and working with existing portfolio companies. A successful candidate will have a strong scientific and/or clinical background and have a good understanding of business principles and market dynamics in the drug and medical device sectors. 

Responsibilities

  • Support the investment process from sourcing through due diligence and deal closing.
  • Perform preclinical and clinical data analysis.
  • Conduct market research.
  • Review regulatory documents and correspondence.
  • Meet with company management.
  • Attend investment and medical conferences.
  • Conduct due diligence calls with physicians and other consultants.
  • Build and maintain financial models.
  • Prepare investment memos on potential investments.
  • Attend board meetings and work on projects to build portfolio company value.

Qualifications

  • MD or PhD in relevant scientific discipline.
  • Prior non-academic work experience in a healthcare consulting, venture capital, buy-side or sell-side equity research, investment banking, or business development role preferred.
  • Strong work ethic and commitment.
  • Strong financial modeling skills.
  • Excellent verbal and written communication skills.
  • High degree of self-motivation and ability to work independently.
  • Ability to multi-task and easily transition among a number of concurrent projects.
  • Ability to thrive in a collaborative and non-hierarchical team environment.     

Compensation

Attractive compensation structure based on team performance.



View and Apply on the DOC website


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Special Agent Science Technology Engineering Math STEM

Date Posted:
4/1/2017

FBI

DC

Many vacancies across US

As a Special Agent for the FBI, you will be responsible for enforcing over 300 federal statutes, as well as conducting sensitive national security investigations. You'll work to develop relationships within and across communities, and educate fellow law enforcement and national security partners at local, state, federal, and international levels. You'll protect the American people and uphold the Constitution of the United States. In an organization made up of careers like no other, being a Special Agent can be a lifelong career of uncommon days and amazing experiences.

You have great problem solving skills, analytical skills and leadership experience and can get things done both in a demanding team environment and independently. Your ability to adapt to changing situations and clearly communicate across management, peer groups, external communities and stakeholders contribute to your ability to keep our nation safe. You're naturally curious yet always driven to find a solution. You are detail-oriented; however, you remain strategic. You know how to objectively evaluate information and make sound judgments. Honesty and integrity are more than just words you use; they are the foundation of who you are. You take pride in making a difference in the communities you serve and bringing your background to the forefront to drive initiatives that impact our most important stakeholders: the American people.

To apply, and to view additional requirements and information, please visithttps://apply.fbijobs.gov/psp/ps/EMPLOYEE/HRMS/c/HRS_HRAM.HRS_CE.GBL?SiteId=1&FolderPath=PORTAL_ROOT_OBJECT.HC_HRS_CE_GBL2&IsFolder=false&IgnoreParamTempl=FolderPath%25252cIsFolder.

Duties

Interviewing a subject for an ongoing investigation in the morning, testifying in court before lunch, planning an operation in the afternoon and speaking at a community event in the evening - that's just one day in the life of a Special Agent.

In this role, you'll be expected to use both established and innovative approaches to tackle some of the toughest challenges of our age. This opportunity should not be taken lightly. The FBI Special Agent position requires significant commitment and dedication from you and your family, but it's an experience you'll never forget.

Though individuals of all backgrounds are highly encouraged to apply, we're specifically seeking individuals with the following skills:

You work in law enforcement or in the military and have been making your way up the ranks for the past few years. You raise challenging questions that demand practical answers and are a go-to resource on your team, squad or unit for help and information. Detective, SWAT, helicopter/jet/rescue pilot, K-9 handler, bomb tech, operational paramedic or otherwise, your loyalty, experience and skills translate perfectly to the Special Agent position with the FBI.

Duties are dependent on position. For further information please refer and apply tohttps://apply.fbijobs.gov/psp/ps/EMPLOYEE/HRMS/c/HRS_HRAM.HRS_CE.GBL?SiteId=1&FolderPath=PORTAL_ROOT_OBJECT.HC_HRS_CE_GBL2&IsFolder=false&IgnoreParamTempl=FolderPath%25252cIsFolder.

Travel Required

  • Occasional Travel
  • Travel is dependent on position. For further information, visit www.fbijobs.gov.

Relocation Authorized

  • Yes
  • Over 56 Field Offices and Resident Agencies across the nation; Legal Attaches across the world.

Job Requirements

Key Requirements

  • Be a US Citizen (by birth or naturalization)
  • Meet employment eligibility requirements (including Bachelor's degree)
  • Be between 23 and 37 years old; age waivers available.
  • Must be able to obtain a Top Secret Security Clearance
  • Possess a valid driver's license
  • Meet the FBI's physical fitness requirements
  • Pass all phases of the Special Agent Selection System
  • Commit to serving as a Special Agent for a minimum of three (3) years

Qualifications

 

  • Adhere to strict standards of conduct, foremost being honesty and integrity.
  • Endure a rigorous background investigation, credit checks and a polygraph in order to obtain a Top Secret Security Clearance.
  • Pass a Physical Fitness Test (PFT) at least twice during the application process. Upon graduation, Agents will also be expected to maintain a level of fitness necessary to effectively respond to life-threatening situations on the job.
  • Pass a medical exam, which includes, but is not limited to, meeting visual and hearing standards.
  • Successfully complete approximately 20 weeks of employment as a Special Agent trainee, while housed at the FBI Academy in Quantico, VA.
  • Upon graduation from the FBI Academy, be available to transfer to one of the FBI's 56 field offices, including San Juan, Puerto Rico or remote resident agencies (satellite offices) to meet the needs of the FBI. Special Agents rarely return to their processing office. Applicants should ensure that their families are prepared for and support this move.
  • Throughout your career, be available for temporary duty assignments, anywhere in the world, on either a temporary or a long-term basis.
  • Work a minimum of a 50-hour workweek, which may include odd hours, and be on-call 24/7, including holidays and weekends.
  • Carry a firearm and be willing to use deadly force if necessary.
  • Be willing and able to participate in arrests, search warrants, raids and other dangerous assignments, all of which may pose the risk of personal bodily harm.
For more information on eligibility requirements see: https://fbijobs.gov/working-at-FBI/eligibility

 

For further information please refer and apply tohttps://apply.fbijobs.gov/psp/ps/EMPLOYEE/HRMS/c/HRS_HRAM.HRS_CE.GBL?SiteId=1&FolderPath=PORTAL_ROOT_OBJECT.HC_HRS_CE_GBL2&IsFolder=false&IgnoreParamTempl=FolderPath%25252cIsFolder.

All Special Agent applicants must also have at least three (3) years of full-time professional work experience unless they qualify for a work experience waiver. Work experience showing progressive growth, leadership and responsibility is preferred.

For more information about the Special Agent Selection System, physical fitness requirements and work experience waivers, please visit https://fbijobs.gov/career-paths/special-agents.

Applicants must follow the Federal Resume Template available at www.fbijobs.gov when submitting their application.

The FBI is an Equal Opportunity Employer and all qualified applicants will receive consideration for this vacancy. Except where otherwise provided by law, selection will be made without regard to, and there will be no discrimination because of color, race, religion, national origin, political affiliation, marital status, parental status, physical or mental disability, genetic information, age, sex, sexual orientation, membership or non-membership in an employee organization, or on the basis of personal favoritism, or any other non-merit factors.

Security Clearance


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Scientist, In Vivo - China

Date Posted:
4/1/2017

Crown Biosciences

INT

1. Ph.D. or M.D. in pharmacology, biology, medicine or related discipline. Masters degree with rich working experience in pharmacology may also qualify.
2. Familiar with animal experiments and drug discovery process. Solid hands-on experience in animal studies, surgeries or necropsy will be a plus.
3. Good at literature searching and review.
4. Good at finding problem; able to creatively resolve different challenges.
5. Strong responsibility and organization ability, good understanding, interpersonal skill, and team work spirit.
6. Good at data analysis using Office software and other statistical software.
7. Excellent verbal and written communication skill in English and Chinese.
8. Scientific publications/presentations in peer-reviewed journals or relevant scientific meetings is a plus.

Requirements

1. Lead a team to execute multiple tasks independently.
2. Responsible for external/internal tumor xenograft model validation and efficacy studies in mice and rats.
3. Directly communicate with the client to finalize the protocol, update the progress and finish the report .
4. Finding and solving problems.
5. Training of technicians.


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Medicinal Chemist

Date Posted:
4/1/2017

Enanta Pharma

MA

About Enanta

Enanta Pharmaceuticals is a research and development-focused biotechnology company that uses its robust chemistry-driven approach and drug discovery capabilities to create small molecule drugs for viral infections and liver diseases. Enanta’s research and development efforts are currently focused on three disease targets: non-alcoholic steatohepatitis (NASH)/primary biliary cholangitis (PBC), respiratory syncytial virus (RSV), and hepatitis B virus (HBV).

Enanta is located in the Boston-area town of Watertown, just minutes from Harvard, MIT, and downtown Boston. Enanta has ample free parking and is also accessible via public transportation. Shopping and a variety of restaurants are within walking distance.
 


Position Summary

We are seeking a highly motivated and productive Medicinal Chemist to conduct daily research on exciting pilot projects of early drug discovery.


Responsibilities

 

  • Design, plan and execute multi-step organic synthesis and purification of high quality target molecules for biological screening.
  • Participate in brainstorming and contribute new proposals and ideas.
  • Interact with colleagues in biology, pharmacology, and DMPK groups.
  • Analyze SAR according to biological, pharmacological and toxicological findings.
  • Assist in the planning and management of external research efforts for contract research organizations and collaborations.
  • Prioritize the chemistry efforts to ensure timeline adherence and project alignment to meet group and company goals.
  • Work cross-functionally with counterparts in process chemistry and CMC groups.
  • Assist in the preparation of patents, publications, and project planning.


Qualifications

 

  • Ph.D. in synthetic organic chemistry with 2 - 7 years pharmaceutical industry experience.
  • Sound knowledge of organic chemistry and medicinal chemistry.
  • Work efficiently and productively in a highly dynamic team environment.
  • Excellent interpersonal and communication skills.


Competencies

 

  • Working independently.
  • Showing initiative
  • Result oriented and effective problem solving skills.
  • Creative, productive, and leads from the bench.
  • Open to suggestions and embraces ideas of others.
  • Learns fast and can change course quickly where indicated.

 

 

How to Apply

Please complete the application below and include the following attachments:

  • Cover Letter

  • CV

  • Research Summary (if applicable)

- See more at: https://theapplicantmanager.com/jobs?pos=et146&fs=1.0em#sthash.OG52Tmr3.dpuf


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Scientist Pharmocokinetics

Date Posted:
4/1/2017

Enanta Pharma

MA

About Enanta

Enanta Pharmaceuticals is a research and development-focused biotechnology company that uses its robust chemistry-driven approach and drug discovery capabilities to create small molecule drugs for viral infections and liver diseases. Enanta’s research and development efforts are currently focused on three disease targets: non-alcoholic steatohepatitis (NASH)/primary biliary cholangitis (PBC), respiratory syncytial virus (RSV), and hepatitis B virus (HBV).

Enanta is located in the Boston-area town of Watertown, just minutes from Harvard, MIT, and downtown Boston. Enanta has ample free parking and is also accessible via public transportation. Shopping and a variety of restaurants are within walking distance.
 


Position Summary

Enanta is seeking an enthusiastic and highly motivated scientist who will be responsible for Pharmacokinetic (PK) analysis, and PK/PD modeling and simulation, in support of Enanta drug discovery/development efforts.  In this role the candidate will serve as a primary source of scientific expertise for the design, analysis, reporting, and presentation of pharmacokinetic and pharmacodynamic modeling and simulation data.  The successful candidate must have in-depth knowledge of pharmacokinetics, pharmacology and PK/PD modeling. Excellent written and oral communication skills, as well as strong organizational skills are essential.  Flexibility and adaptability are also necessary.


Primary Responsibilities

  • Perform pharmacokinetic analysis, interpretation, and reporting of exposure data to support all the Enanta discovery and development programs.

  • Implement PK/PD approaches early in non-clinical development including modeling of disease progression in various animal models to support translational research.

  • Conduct physiologically-based pharmacokinetic (PBPK) modeling analysis to support dose selection for toxicology studies and first-in-man studies.

  • Perform simulation of drug-drug interactions for quantitative risk assessment.

  • Address and resolve scientific issues arising in drug discovery/development programs.

  • Interact with multidisciplinary teams (including chemists, toxicologists and clinical managers) to meet project goals and timelines.

  • Communicate unambiguous critical and significant project information to project teams, Enanta leadership, and others as required.


General Qualifications

  • Hands-on experience with PK analysis and PK/PD modeling using Phoenix WinNonlin, Simcyp, and/or NONMEM is a must.

  • Knowledge of regulatory guidance for PK analysis and GLP compliance is a plus.

  • Excellent interpersonal skills with an ability to work effectively in a team setting/matrix-type organization.

  • Excellent oral and written communication capabilities.


Education and Experience Requirements

  • Ph.D. in Pharmacokinetics, Pharmacology, Pharmaceutical Sciences, or related field with a specific focus on pharmacokinetics and PK/PD modeling.

 

How to Apply

Please complete the application below and include the following attachments:

  • Cover Letter

  • CV

  • Research Summary (if applicable)

- See more at: https://theapplicantmanager.com/jobs?pos=et216&fs=1.0em#sthash.ANTGWTXx.dpuf


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Scientist In Vitro Drug Transporter Studies

Date Posted:
4/1/2017

Enanta Pharma

MA

About Enanta

Enanta Pharmaceuticals is a research and development-focused biotechnology company that uses its robust chemistry-driven approach and drug discovery capabilities to create small molecule drugs for viral infections and liver diseases. Enanta’s research and development efforts are currently focused on three disease targets: non-alcoholic steatohepatitis (NASH)/primary biliary cholangitis (PBC), respiratory syncytial virus (RSV), and hepatitis B virus (HBV).

Enanta is located in the Boston-area town of Watertown, just minutes from Harvard, MIT, and downtown Boston. Enanta has ample free parking and is also accessible via public transportation. Shopping and a variety of restaurants are within walking distance.
 


Position Summary

Enanta is seeking an enthusiastic and highly motivated Scientist who will be responsible for in vitro drug transporter research related to drug disposition and drug interactions.  The successful candidate must have in-depth knowledge and hands-on experience with drug-drug interaction-related transporter studies.  Excellent written and oral communication skills, as well as strong organizational skills are essential.  Flexibility and adaptability are also necessary.

 

Primary Responsibilities

  • Lead, design, and conduct the in vitro drug transporter studies (including Caco-2 permeability, substrate and inhibition assays related to BCRP, PgP and MRP2, etc.) in-house.

  • Identify appropriate contract labs for some drug transporter studies, if necessary, and oversee the contract work to ensure the high quality of study reports.

  • Address and resolve scientific issues arising during the studies.

  • Interact with multidisciplinary teams (including chemists, toxicologists, and clinical managers) to meet project goals and timelines.

  • Communicate unambiguous critical and significant project information to various bodies, including project teams and Enanta leadership, as required.


Education and Experience Requirements

  • Ph.D. in drug transporter or relevant field.

  • A minimum of three years of experience with the in vitro drug transporter studies.

  • In depth understanding and working knowledge of regulatory guidance for drug transporters.

  • Strong problem solver who is highly organized with the ability to thrive and to lead in an environment with rapidly changing priorities.

  • Excellent interpersonal skills with an ability to work effectively in a team setting/matrix-type organization.

  • Excellent oral and written communication capabilities.

 

How to Apply

Please complete the application below and include the following attachments:

  • Cover Letter

  • CV

  • Research Summary (if applicable)

- See more at: https://theapplicantmanager.com/jobs?pos=et226&fs=1.0em#sthash.5w6KNRUk.dpuf


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Bioanalytical Scientist

Date Posted:
4/1/2017

Enanta Pharma

MA

About Enanta

Enanta Pharmaceuticals is a research and development-focused biotechnology company that uses its robust chemistry-driven approach and drug discovery capabilities to create small molecule drugs for viral infections and liver diseases. Enanta’s research and development efforts are currently focused on three disease targets: non-alcoholic steatohepatitis (NASH)/primary biliary cholangitis (PBC), respiratory syncytial virus (RSV), and hepatitis B virus (HBV).

Enanta is located in the Boston-area town of Watertown, just minutes from Harvard, MIT, and downtown Boston. Enanta has ample free parking and is also accessible via public transportation. Shopping and a variety of restaurants are within walking distance.
 


Position Summary

Enanta is seeking an enthusiastic and highly motivated Scientist who will be responsible for LC/MS/MS bioanalytical method development/validation, biological sample analysis, and in vitro/ex vivo drug metabolism studies.  The successful candidate must have in depth knowledge of regulatory guidance for bioanalysis and GLP compliance, separation science, analytical instrumentation (e.g., API 6500 & 4500 LC/MS/MS, etc.) and their application to bioanalysis.  Excellent written and oral communication skills, as well as strong organizational skills are essential.  Flexibility and adaptability are also necessary.


Primary Responsibilities

  • Design and oversee GLP-regulated bioanalytical method development, validation, and sample analysis

  • Manage a bioanalytical lab and keep the instruments running properly.

  • Conduct enzymatic assays and in vitro/ex vivo drug metabolism studies, including liver microsome stability testing in different species, cytochrome P450 inhibition, hepatocyte metabolism, and metabolite identification, etc.

  • Address and resolve scientific issues arising in drug discovery/development programs.

  • Interact with multidisciplinary teams (including chemists, toxicologists, and clinical managers) to meet project goals and timelines.

  • Communicate unambiguous critical and significant project information to various bodies including project teams and Enanta leadership as required.


Qualifications and Requirements

  • Ph.D. in Bioanalytical Chemistry or relevant field.

  • A minimum of three years of experience with bioanalytical method development and validation.

  • In depth understanding and working knowledge of regulatory guidance for bioanalysis and GLP compliance.

  • Strong problem solver who is highly organized with the ability to thrive and to lead in an environment with rapidly changing priorities.

  • Excellent interpersonal skills with an ability to work effectively in a team setting/matrix-type organization.

  • Excellent oral and written communication capabilities.

 

How to Apply

Please complete the application below and include the following attachments:

  • Cover Letter

  • CV

  • Research Summary (if applicable)

- See more at: https://theapplicantmanager.com/jobs?pos=et227&fs=1.0em#sthash.Zduk4RON.dpuf


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Scientist Biology

Date Posted:
4/1/2017

Enanta Pharma

MA

About Enanta

Enanta Pharmaceuticals is a research and development-focused biotechnology company that uses its robust chemistry-driven approach and drug discovery capabilities to create small molecule drugs for viral infections and liver diseases. Enanta’s research and development efforts are currently focused on three disease targets: non-alcoholic steatohepatitis (NASH)/primary biliary cholangitis (PBC), respiratory syncytial virus (RSV), and hepatitis B virus (HBV).

Enanta is located in the Boston-area town of Watertown, just minutes from Harvard, MIT, and downtown Boston. Enanta has ample free parking and is also accessible via public transportation. Shopping and a variety of restaurants are within walking distance.
 


Position Summary

Enanta is seeking an enthusiastic and highly motivated Scientist who will lead biological assay development to support Enanta drug discovery/development in the nonalcoholic steatoheptitis (NASH) /metabolic disease areas.  The individual will be expected to conduct experiments in the laboratory and provide scientific and strategic input into the target portfolio, preclinical animal models and novel in vitro techniques supporting the programs.  The successful candidate must have in depth knowledge of metabolic pathways of nuclear receptors.  Excellent written and oral communication skills, as well as strong organizational skills are essential.  Flexibility and adaptability are also necessary.


Primary Responsibilities

  • Design and implement experiments, analyze data, interpret and communicate results to drive scientific innovation and enable effective decision making in the NASH/metabolic disease drug discovery projects
  • Address and resolve the in vitro assay development issues arising in drug discovery programs
  • Interact with multidisciplinary teams to meet project goals and timelines
  • Communicate unambiguous critical and significant project information to various bodies including project teams and Enanta leadership as required


Qualifications and Requirements

  • Ph.D. with post-doctoral experience in Physiology, Biology, Biochemistry, Molecular Biology, Pharmacology, Metabolic Disease or a related discipline, along with a strong track record of publication in the area of nuclear receptors, nonalcoholic fatty liver and/or metabolic diseases is required

  • Exceptional knowledge of basic and emerging concepts in nonalcoholic fatty liver /metabolic diseases, particularly pathways that regulate glucose, lipid and bile acid metabolism

  • Demonstrated success in the in vitro assay development and execution (biochemical, receptor and/or cell based), compound screening, and statistical analyses of data.

  • Strong problem solver who is highly organized with the ability to thrive and to lead in an environment with rapidly changing priorities

  • Excellent interpersonal skills with an ability to work effectively in a team setting/matrix-type organization

  • Excellent oral and written communication capabilities

 

How to Apply

Please complete the application below and include the following attachments:

  • Cover Letter

  • CV

  • Research Summary (if applicable)

 


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Technical Service Scientist

Date Posted:
4/1/2017

BioLegend

CA

BioLegend develops world-class, cutting-edge antibodies and reagents for biomedical research, manufactured in our state-of-the-art facility in San Diego. Our mission is to accelerate research and discovery by providing the highest quality products at an outstanding value, along with superior customer service and technical support. Our product expertise covers a diverse set of research areas including Immunology, Neuroscience, Cancer, Stem cells, and Cell Biology.

BioLegend is looking for a Technical Service Scientist with an Immunology background for a position in San Diego! The responsibilities of this position include responding to technical-related customer and distributor emails and phone calls, contributing to technical writing of marketing literature and other materials, contributing to website content, and participating in business development marketing, and sales activities, including attending trade shows and generating new leads while interacting with several departments.

Essential Functions:

  • Putting the customer front and center, providing technical information and troubleshooting help via telephone and emails, and customer follow up
  •  Utilizing scientific skills, not only to provide product related education to the customers, but also help to identify potentially non-conforming products based on available data
  • Contributing to the updating of scientific content on the company website in terms of posters, product data sheets, and web tools under tight deadlines.
  • Identifying potential new products or product lines and attending scientific meetings and trade/vendor shows
  • Careful and diligent documentation of any and all of technical issues in compliance with ISO

Knowledge, Skill and Experience:

  • Bachelor’s, Master’s, or PhD degree
  • Must have 3+ years of hands-on experience and troubleshooting ability in multi-color flow cytometry (at least six colors)
  • Experience with Western Blotting, Immunofluorescence, Immunohistochemistry, ELISA, and multiplex assays is also welcome, but secondary to flow cytometry abilities
  • Must have an excellent background specifically in immunology, and be able to effectively search and read primary literature, as well as be knowledgeable with research tools, including website databases and instrumentation
  • Must be a self-starter, highly motivated, dependable, and friendly
  • Must also have problem solving, analytical, and quantitative skills and able to work independently as well as in a TEAM environment, supporting and helping colleagues on a daily basis
  • Must also be an excellent communicator that conveys information easily and readily

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Cell Biology Scientist

Date Posted:
4/1/2017

BioLegend

CA

BioLegend develops world-class, cutting-edge antibodies and reagents for biomedical research, manufactured in our state-of-the-art facility in San Diego, CA.  Our mission is to accelerate research and discovery by providing the highest quality products at an outstanding value, along with superior customer service and technical support. Our product expertise covers a diverse set of research areas including Immunology, Neuroscience, Cancer, Stem cells, and Cell Biology. 

BioLegend is seeking a highly motivated, responsible Cell Biology Scientist with leadership skills to join our Cell Biology Group. This individual will function as an integral member of the Molecular Cellular Immunology team. The primary responsibilities for this position will include performing projects related to the identification of cell type specific markers, proposing plans for new antibody development, implement the plans for testing, and launching the products to the research community market.

Essential Functions:

Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

  • Build and direct a team of research associates/scientists focused on new target identification and development of antibody and associated products
  • Be an integral part of the team, focusing on broad targets related to, but not limited to, immunology research
  • Lead the team in testing new antibodies, including specificity and cross-reactivity
  • Analyze data and results of experiments and prepare recommendations for improvement or trouble shooting
  • Support the technical service team with trouble shooting of cell biology related products

Competencies

  • Motivated team player with commitment to quality, attention to detail, and strong problem solving skills
  • Strong record of publication, organizational skills, and the ability to work in a highly collaborative environment
  • Excellent written and verbal communication skills

Minimum  Qualifications - Education and Experience 

  • PhD. in cell Biology, Immunology, or other related Biological Science area
  • Extensive experience with cell culture technique and various cell treatment protocols
  • Experience with various techniques, including but not limited to, Western blotting and immunoprecipitation
  • Experience with mouse and rat handling and with isolation and culture of primary cells
  • Familiar with Microsoft Word, EXCEL, PowerPoint, and Filemaker database

 

Preferred Qualifications – Education and Experience

  •  Previous experience with fluorescent microscopy and high resolution confocal microscopy is highly desirable.

 


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Staff Scientist Neuroimaging

Date Posted:
4/1/2017

NIDA

MD

Position Description:
The National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), is recruiting for a Staff Scientist to conduct neuroimaging research within its Intramural Research Program (IRP) located in Baltimore, Maryland. The goal of this search is to identify a candidate who will enhance this collaborative environment within the Neuroimaging Research Branch (NRB).

Qualifications:
We are seeking a candidate who is committed to scientific excellence, and understands the intellectual benefits of collaborative research to conduct state-of-art research on fundamental mechanisms that underlie drug addiction and to develop strategies for the treatment of the disorder. Applicants must hold an MD, PhD or equivalent degree. Criteria for selection include solid training in neuroimaging technologies (functional MRI, structural MRI, magnetic resonance spectroscopy, etc.) and substantial experience in conducting research on neuroimaging of drug addiction in humans and preclinical models.

Duties:
The selected candidate will carry out the research within the Neuroimaging Research Branch, and will be responsible for setting up research protocols, conducting experiments on human participants and preclinical models, training new trainees (post-doctoral, pre-doctoral and post-bachelor fellows), as well as collaborating with other intramural and extramural research groups. Salary will be commensurate with experience.

To Apply:
The position is open to both U.S. and non-U.S. citizens. Interested candidates must submit a curriculum vita, bibliography, a one-page summary of research interests, and the names and contact information (work/email addresses, phone) of three references (via pdf or Microsoft word format only - paper applications will not be accepted) to: Yihong Yang, Senior Investigator, atyihongyang@mail.nih.gov

Review of applications will begin in late April 2017, and continue until the position is filled


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Staff Scientist Visual Neurophysiology

Date Posted:
4/1/2017

NINDS

MD

Position Description:
This Staff Scientist would work within the Synaptic Physiology Section (SPS), a laboratory within the NINDS intramural Research Program headed by Dr. Jeffrey Diamond (https://neuroscience.nih.gov/Faculty/Profile/jeffrey-diamond.aspx). The SPS is part of a large neuroscience community comprising laboratories from a dozen different NIH Institutes and featuring outstanding groups in membrane biophysics, cell and developmental biology, synapse and circuit physiology, and translational/clinical neurosciences.

Qualifications:
The successful candidate will perform original visual neuroscience research, help develop new experimental and analytical methods and train SPS personnel. The position requires extensive experience with retinal dissections, whole-cell patch clamp electrophysiology and multiphoton fluorescence imaging, as well as facility with scientific programming software (e.g., Igor Pro and Matlab). The ideal candidate would exhibit outstanding interpersonal and teamwork abilities, as well as highly developed oral and written communication skills to collaborate effectively with other scientists. The candidate must have a Ph.D. in a relevant discipline, at least 5 years of visual neuroscience-related postdoctoral experience, and a strong publication record.

To Apply:
Interested candidates should e-mail their CV, a list of publications, a brief statement of research interests, and recommendation letters from at least two qualified referees to Jeffrey Diamond (diamondj@ninds.nih.gov).


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Sr. Scientist Product Development

Date Posted:
4/1/2017

Fenologica Biosciences

WA

Company Description:
FenoLogica Biosciences, Inc. is an early stage startup biotechnology company developing a platform that will fill an existing market gap and address unmet needs in the biomedical research community. The initial product is an automated imaging system and analysis software suite that enables high-throughput, high-content phenotype analysis and classification of microbial samples.

Job Summary:
FenoLogica is seeking an experienced Scientist to join our product development team. This individual will be the scientific subject matter expert, represent the company internally and externally, and work with a cross functional team to develop a new platform instrumentation and cloud based analytical tools, that will enable new technologies and accelerate the pace of microbial research.

The focus of this position is on guiding the scientific direction of product development across a board range of scientific applications, experimental workflows, and fields of study. This Scientist level position will work in a dynamic startup environment with minimal lab work. S/he may be required to supervise the activities of others and will work collaboratively with the FenoLogica's research and product development teams.
The position is initially a fractional advisory role (10 -20 hours/week) with the opportunity for a motivated candidate to create a full time position within the team as the company achieves milestones and scale.

Job Responsibilities:

  • Scientific subject matter expert (fields include microbiology, cell and molecular biology and high throughput screening/ large scale genetic analysis)
  • Work closely with Product Manager and potential customers (other scientists) to evaluate and translate customer needs into product requirements
  • Keep pace with relevant scientific literature, competitive offerings, market trends and market analysis
  • Use knowledge of microbiology and/or biopharma discovery techniques to identify, develop and validate new research and market applications with product team
  • Work as part of multidisciplinary team to deliver new research, discovery and diagnostic applications on tight timelines
  • Support internal authorship of technical or industry specific collateral and whitepapers

Basic Qualifications (Education, Experience, Specific Skills):

  • Experience within both an institutional research and biopharma industry discovery environment is highly desirable.
  • PhD in microbiology, molecular or cellular biology, genetics, bioengineering or related biological science field with a minimum of three years of relevant post-doctoral and industry work experience, or an M.S. with commensurate relevant industry work experience.
  • Experience in high throughput screening in yeast and bacterial systems or pathology core laboratory facility and/or clinical microbiology lab
  • Extensive knowledge of classical and leading edge techniques in the areas of microbiology, clinical microbiology, lab automation, imaging, bio-informatics and quantitative analytical tools
  • Careful attention to detail, excellent interpersonal skills, oral and written skills.
  • Ability to communicate effectively with technical personnel, executive management, investors and customers
  • Ability to work independently, virtually and in a collaborative, multidisciplinary
  • environment in academic and industrial settings
  • Experience developing microbiology research or diagnostic instrumentation or products in Biotech or Pharma company/industry
  • Experience working in an ISO certified, GLP or QSR certified facility
  • Experience with image processing and analysis and machine learning approaches
  • Management and consulting experience

To Appy:
Submit inquiries, cover letter and resume/CV to: info@fenologica.com


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Manager Office Postdoctoral Affairs

Date Posted:
4/1/2017

Sloan Kettering

NY

Company Overview:
At Memorial Sloan Kettering (MSK), we're not only changing the way we treat cancer, but also the way the world thinks about it. By working together and pushing forward with innovation and discovery, we're driving excellence and improving outcomes.
For the 27th year, MSK has been named a top hospital for cancer by U.S. News & World Report. We are proud to be on Becker's Healthcare list as one of the 150 Great Places to Work in Healthcare in 2016, as well as Glassdoor's annual Employees' Choice Awards 2017. We're treating cancer, one patient at a time. Join us and make a difference every day.

Job Description:
The Office of Postdoctoral Affairs (OPA) is dedicated to enhancing the academic, collegial, and professional environment for postdoctoral trainees at Memorial Sloan Kettering Cancer Center. OPA serves as a resource for current and prospective postdoctoral trainees as well as for faculty and administrators.

We are currently seeking a Manager for the Office of Postdoctoral Affairs to oversee postdoctoral relations and training, departmental programs and events, communications, and budget.

Responsibilities:

  • Balance business and creative goals to develop new and existing programs from inception through implementation and maintenance
  • Stay abreast of the needs of postdocs at MSK and identify new ideas and innovative suggestions for improving postdoctoral experiences at MSK
  • Proactively build relationships with postdocs, faculty, and key stakeholders across MSK to serve as the first point of contact to address all postdocs questions and to reliably meet the needs of the postdoctoral community at all levels: administrative, professional and personal
  • Plan and prioritize project work aligned with organizational goals. Lead and manage day-to-day project activities for complex initiatives with multi-departmental teams and across stakeholders
  • Design, develop, and manage the communication strategy for internal and external audiences
  • Organize and lead the annual Postdoc Symposium and appreciation events. Liaise with Public Affairs to develop news articles, blog posts, and creative outlets for postdocs to receive recognition. Develop and maintain external postdoc websites, intranet pages, and monitor PDA websites (Facebook, Twitter)
  • Design training curriculum and deliver some course content. These include, but are not limited to, courses in English as a second language, writing/communication, grantsmanship, retirement savings & taxation
  • Manage and maintain overall OPA budget by preparing the annual budget, monitoring expenses, tracking and reporting variances

Qualifications:

  • Adept at creating partnerships and working collaboratively with others to meet shared objectives and goals.
  • A good decision-maker, with proven success at making timely decisions that keep the organization moving forward.
  • Action-oriented and eager to embrace new opportunities and tough challenges with a sense of urgency, high energy, and enthusiasm.
  • An effective communicator, capable of determining how best to reach different audiences and executing communications based on that understanding.
  • Flexible in your approach and demeanor in order to align with the shifting demands of evolving circumstances.

Requirements:
A PhD degree with post doctoral experience in an academic environment or a Bachelor's or Master's degree with 5+ years experience working in a management role within an Office of Postdoctoral Affairs

To Apply:
For more information and to apply online, please visit this posting.

MSK is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision.
Federal law requires employers to provide reasonable accommodation to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job. Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment.


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Education and Broadening Participation Manager

Date Posted:
4/1/2017

University of Colorado,Boulder

CO

Position Description:
We seek to fill a full time Education and Broadening Participation Manager position within the new National Science Foundation STROBE Science and Technology Center for Real-Time Functional Imaging. The successful candidate will serve as the day-to-day project manager for STROBE activities directed to education and broadening participation.

STROBE is a partnership of University of Colorado Boulder, UC Berkley, UC Los Angeles, UC Irvine, Fort Lewis College, and Florida International University. The mission of Strobe is to create powerful and broadly-applicable real time nano-to-atomic scale imaging modalities to advance imaging science and increase access, that can be used to address grand challenges in science and technology, while building a diverse STEM workforce. In addition to research, STROBE emphasizes knowledge transfer, education and broadening participation in the STEM workforce. For more information about STROBE, visit STROBE.colorado.edu

The goals of STROBE's Education and Broadening Participation efforts are to develop, implement, assess and disseminate new education programs, innovative instructional materials, and models for other programs that inspire and prepare a diverse group of students to be innovative and globally competitive in imaging science and technology. STROBE will create unique learning approaches and experiences in imaging science through the four core and integrated programmatic approaches described below, that focus on transforming graduate programs, developing new pathways for those underrepresented in our fields, efforts in communication and engaging the public, and developing models for transdisciplinary STEM education.

The major strategic areas of focus of the EBP activities and programming are as follows:

  1. Graduate Education: Create transformative graduate programs in imaging science that are adapted to current and future students and opportunities to prepare them for a full range of career options including academe, industry, national laboratories and entrepreneurship
  2. Educational Pathways: Establish closely coordinated partnerships and programs that increase the overall number and success of a diverse group of students, especially women, first generation university students, and underrepresented minorities in Imaging Sciences
  3. Communication & the Public: Enhance the communication and collaboration skills of all Center members through training and experience
  4. Modeling Learning & Transformation: Develop and implement a model for transdisciplinary STEM education that promotes and sustains a culture of diversity, inclusion, success and adaptability through research on learning and systemic change in imaging sciences

We seek a team member to serve as day-to-day operational manager and coordinator of a diverse portfolio of educational and broadening activities. The EBP Manager will be supervised by the Director of Education, in partnership with the Center Leadership team. The scope of work will include the following:

  • Implement, enhance, and report on the activities and actions of the STROBE Strategic Plan in order to attain the strategic EBP outcomes listed above
  • Integrate and implement Center-wide education and outreach efforts, including existing site-specific (local) activities and new cross-institutional collaborations and projects, taking advantage of the unique opportunities available at different partner institutions
  • Proactively engage with all Center members to integrate education with the research and knowledge transfer thrusts of STROBE
  • Cultivate, grow, and maintain external partnerships to achieve the Center's strategic objectives
  • Manage routine operations of the educational program, including: encouraging communication and coordination among team members, including regular team meetings; overseeing data collection and reporting on EBP outcomes
  • Communicate and disseminate EBP efforts through writing, web, public talks, and other media
  • - Expand STROBE EBP efforts through proposals or by other means.

The successful candidate will be an employee of CU Boulder. The initial appointment will be for 24 months, renewable subject to University policies and the availability of funding.

Qualifications:
Required:
The successful candidate will have:

  • A PhD or equivalent experience in a STEM area (science, technology, engineering, and mathematics), with substantial experience in education and outreach; or a PhD or equivalent experience in education, with MS-level background in a STEM field
  • Management experience in a Center-like organization that integrates activities across multiple partners
  • Experience working in a team-oriented, shared-values environment
  • Experience in communicating effectively in oral and written formats, including presentations, websites, and social media
  • Experience with writing and reporting on successful proposals
  • Experience with data collection and reporting of program outcomes

Preferred:
Preferred qualifications include evidence of:

  • Experience with Education and Broadening Participation efforts in an NSF Science or Engineering Center
  • Experience with Knowledge Transfer efforts in an NSF Science or Engineering Center, including professional development of graduate students, postdoctoral scholars, and teachers
  • Experience with successful RET and REU programs that aim to diversify the STEM workforce
  • Experience with developing and coordinating STEM outreach programs
  • Previous work with STEM graduate education reform efforts
  • Capacity for independence and creativity

To Apply:
Review of applications will begin April 14, 2017 and will continue until the position is filled. Questions may be directed to Lauren Mason at: masonlw@jila.colorado.edu This position is eligible for medical, dental and life insurance, retirement benefits programs, and is eligible for monthly vacation and sick leave accruals. The University of Colorado Boulder conducts background checks on all final applicants being considered for employment, prior to the issuance of an offer letter. The Immigration Reform and Control Act requires that verification of employment eligibility be documented for all new employees by the end of the third day of work.

To apply, please submit the following materials to this posting: 1) Cover Letter - A statement illustrating how the applicant meets the required and preferred qualifications. Please discuss any experiences that would be relevant to the project. Maximum length 5 pages. In addition, a list of successful grants, authored reports, and examples of communication via web sites or other mediamay be provided; maximum length 1 page. 2) A current and complete Curriculum Vitae 3) List of Reference - names and contact information for 3 references who have agreed to provide letters upon request


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Medical Scientist Oncology

Date Posted:
3/25/2017

Astra Zeneca

MD

Location:Gaithersburg, Maryland, United StatesJob reference: R-002917Posted date: Jan. 18, 2017

 

At AstraZeneca we work together across global boundaries to make an impact and find answers to challenges. We do this with the upmost integrity even in the most difficult situations because we are committed to doing the right thing. We continuously forge partnerships that help pursue world-class medicines in new ways, combining our peoples exceptional skills with those of people from all over the globe. As a Clinical Scientist, Oncology youll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients lives. GMD (Global Medicines Development) drives late-stage development of our innovative pipeline, transforming exciting science into valued new medicines and ensuring patients around the world can access them.

 

AstraZenecas vision in Oncology is to help patients by redefining the cancer-treatment paradigm, with the aim of bringing six new cancer medicines to patients between 2013 and 2020. A broad pipeline of next-generation medicines is focused principally on four disease areas - breast, ovarian, lung and hematological cancers. As well as other tumor types, these are being targeted through four key platforms - immunotherapy, the genetic drivers of cancer and resistance, DNA damage repair, and antibody drug conjugates, underpinned by personalized healthcare and biomarker technologies.

 

Main Duties and Responsibilities

 

Were currently looking for a Medical Scientist

 

Oncology to play a leading role in our Clinical Research team. Well look to you to act as an expert in your area, working independently with guidance in only the most complex situations. You will serve as a close partner to the study physicians, coordinating the activity of a research team and holding full accountability for projects, often with Global impact. You may have the opportunity to act as a coach or team leader for more junior team members.

 

This position will be focused on combination therapies and will have key relationships internally with clinical project teams, regulatory affairs, marketing and business development, and brand or therapy area team leaders, and externally with regulatory bodies and external service providers. With our outstanding Oncology pipeline and a culture that empowers scientists to make bold decisions driven by science, this is an incredible opportunity to gain plenty of exposure to submissions and progress within a core therapeutic area.

 

Your main responsibilities will involve: developing and designing studies to determine the scientific or commercial viability of a particular drug or portfolio of drugs and interpret the results of these studies, either as the head of a team, or by providing expert input; contributing to the decision making process as a valued expert to determine the commercial and scientific viability of drugs; review and interpretation of medical and clinical trial data to reach conclusions; literature searches and authoring background section of the disease from the literature search. You will have responsibility for delivery of pieces of the trials and may lead submissions from a process standpoint.

 

Essential Requirements

 

Master's degree in a scientific field supported by a proven record of managing and interpreting clinical trials.

 

Experience managing and interpreting the results of clinical trials

 

Excellent collaboration and communication skills

 

Adept at working in a global setting and matrix environment.

 

Adept at partnering with a diverse team and delivering results through taking ownership of crucial program components.

 

Desired Requirements

 

An advanced degree (i.e. PhD, PharmD) in a relevant scientific discipline.

 

Project management experience

 

Strong clinical, technical or disease area expertise in oncology is strongly preferred

 

Next Steps

 

Apply today!

 

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity. If you know someone who would be a great fit, please share this posting with them.

 

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.


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Bioinformatics Analsyt

Date Posted:
3/25/2017

Leidos

MD

Job description

Leidos Biomedical Research, Inc. (LBRI), a wholly owned subsidiary of Leidos, operates the Frederick National Laboratory for Cancer Research (FNLCR). FNLCR is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI). It is the only FFRDC dedicated to biomedical research. Through its status as an FFRDC, FNLCR provides NCI and others with a unique national resource to accelerate the development and delivery of effective preventive, diagnostic, and therapeutic products for cancer and AIDS.

 

The breadth of FNLCRs activities spans the research and development spectrum, including investigator-initiated, hypothesis-driven research into cancer and AIDS; advanced technology programs focused on genetics and genomics, proteins and proteomics, imaging, nanotechnology, bioinformatics, and laboratory animal sciences; clinical operations in support of NCI and National Institute of Allergy and Infectious Diseases (NIAID)-sponsored clinical trials, as well as NCI drug discovery and development efforts; and management and operations of biopharmaceutical development and manufacturing programs under current Good Manufacturing Practice conditions for NCI and NIAID. Administrative, procurement, financial, safety, and facilities support is provided to these R activities through state-of-the-art business processes. LBRI has approximately 1,900 employees and manages an annual operating budget of approximately $450M.

 

For more information about Leidos Biomedical Research Inc., please visit our webpage at https://www.leidos.com/about/companies/leidos-biomedical-research.

 

Program Description

 

The Advanced Biomedical Computing Center (ABCC) is a part of the Data Science and Information Technology Program at Leidos Biomedical Research, Inc. The ABCC provides technology development, scientific consultation, collaboration and training, and high-performance computing support to the NCI and NIH scientists and staff.

 

Job Description

 

This position description does not represent a current opening but may be used to identify candidates with skills and experience for positions within Leidos Biomedical Research that frequently become available. Candidates who express an interest may be considered for future positions at Leidos Biomedical Research.

 

The ABCC is seeking Bioinformatics Analyst candidates at all levels to work in the NCI Center for Cancer Research (CCR) Collaborative Research Resource (CCBR). The CCBR provides collaborative bioinformatics support to CCR investigators at the National Cancer Institute (NCI). CCBR bioinformatics analysts are responsible for

 

The analysis and interpretation of high-throughput biomedical data generated by microarray, next-generation sequencing, proteomics and metabolomics platforms

 

Designing, developing and deploying robust workflows, as well as custom scripts, to support the analysis of high-throughput data

 

Mining proprietary and publicly available biological data to generate novel hypotheses or insights

 

Presenting analysis results, in a clear and concise manner, to scientific audiences. Bioinformatics Analysts are expected to work effectively as a member of a team; coordinate activities among other groups located at the Bethesda, Frederick, Rockville and Gaithersburg NCI campuses; follow sound scientific practices and maintain effective documentation of activities and analyses. Majority of time will be spent on the main NIH campus in Bethesda.BASIC QUALIFICATIONS

 

Bachelors, Masters or PhD degree in life science/bioinformatics/math/physics/computer related field from an accredited college according to the Council for Higher Education Accreditation (CHEA)

 

Foreign degrees must be evaluated for U.S. Equivalency.

 

Below are the typical skills we are looking for in candidates:

 

Processing high throughput biomedical data: data cleaning, normalization, analysis, interpretation and visualization

 

Data analysis for complex experiments

 

Experience with high throughput analysis pipelines such as, metagenomics, ChIPSeq, RNASeq, ExomeSeq, microarray analysis

 

Experience in using tools for NGS data-processing tools

 

Familiarity with public databases: NCBI, Ensembl, TCGA, cBioPortal, Broad FireHose

 

Knowledge of database programming and working in a cluster environment

 

Ability to work in collaborative environment and contribute to team projects

 

Ability to work without close supervision

 

Below are the desired skills we are looking for in candidates:

 

Applied statistics and design of experiments

 

Application development experience

 

Experience in submitting data sets to public repositories

 

Management of large genomic data sets including integration with data available from public sources

 

Knowledge of cancer biology

 

Experience with bioinformatics tools such as: Novoalign, STAR, BWA, GATK, Samtools, Annotator, SnpEff, Limma, EdgeR, DESeq2

 

Proficiency in one, preferably two, of the following programming languages: Perl, Python, R, Java and C/C++

 

This position description does not represent a current opening but may be used to identify candidates with skills and experience for positions within Leidos Biomedical Research that frequently become available. Candidates who express an interest may be considered for future positions at Leidos Biomedical Research

 

Leidos Overview

 

Leidos is a global science and technology solutions leader working to solve the worlds toughest challenges in the defense, intelligence, homeland security, civil, and health markets. The companys 33,000 employees support vital missions for government and commercial customers. Headquartered in Reston, Virginia, Leidos reported pro forma annual revenues of approximately $10 billion for the fiscal year ended January 1, 2016 after giving effect to the recently completed combination of Leidos with Lockheed Martin's Information Systems & Global Solutions business (IS). For more information, visit www.Leidos.com. The companys diverse employees support vital missions for government and commercial customers. Qualified women, minorities, individuals with disabilities and protected veterans are encouraged to apply. Leidos is an Equal Opportunity Employer.


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Scientific Program Manager

Date Posted:
3/25/2017

Cherokee Nation Technology Solutions

MD

Our client, the Armed Forces Health Surveillance Branch (AFHSB), strives to be the central epidemiologic resource and a global health surveillance proponent for the U.S. Armed Forces. The AFHSB provides timely, relevant, actionable, and comprehensive infectious disease surveillance information to promote, maintain, and enhance the health of military and military-associated populations.

 

We are seeking a program manager with a public health/epidemiology background to provide program management support for the Global Emerging Infections Surveillance Section (GEIS) of AFHSB. The incumbent will support the client by providing GEIS program coordination and oversight services to ensure smooth operations of the GEIS program in its mission to enhance force health protection. Successful candidates will have strong program management and organizational skills and experience working with U.S. government agencies such as the DoD.

 

Responsibilities

 

  • Provide program management leadership to accomplish long-range goals and short-term objectives for the GEIS program office and the GEIS network and ensure excellence in strategic, financial, operational, tactical and organizational functions of the GEIS program;
  • Provide GEIS program coordination and oversight services to ensure smooth operations of the GEIS program, including task management, establishing timelines and milestones, and tracking deliverables;
  • Provide key support to identifying and defining process, outcome variables, and metrics, including return on investment, to assess success and failure of GEIS-funded surveillance efforts and initiatives;
  • Support the development of publications, presentations, and timely information products based on GEIS-funded surveillance for DoD leaders and other stakeholder, in support of force health protection;
  • Provide guidance on best practices for proposal management;
  • Support the review and prioritization of programmatic/focus area-specific strategies, programs, projects, and proposals to ensure alignment with overarching GEIS strategic direction, and provide recommendations on enhanced alignment and opportunities to address critical organizational gaps;
  • Provide scientific/technical input for GEIS on infectious disease surveillance projects and programs across the GEIS Focus Areas as needed;
  • Perform other duties as needed.

     

Qualifications

 

  • Graduate degree in Public Heath, Epidemiology, Biostatistics, Microbiology, Molecular Biology, or related field required; doctoral degree (PhD, MD, DO, DVM, DrPH, or related degree) preferred; minimum 8 years of experience in laboratory, research, or public health setting required;
  • Program management experience and experience in proposal management required;
  • Experience managing projects and staff to ensure timely delivery of high quality products to the government client;
  • Experience in designing or maintaining relational databases preferred;
  • Analytical and organizational skills to synthesize data into informational reports to support program evaluation;
  • Excellent organizational skills and strong oral and written communication skills;
  • Ability to collaborate with other professionals;
  • Demonstrated experience supporting Federal clients, particularly DoD, preferred;
  • Active Secret clearance preferred; applicants selected will be subject to a U.S. Government security investigation and must meet eligibility requirements for Secret clearance.

     

Applicants selected will be subject to a U.S. Government security investigation and must meet eligibility requirements for access to classified information.

 

Apply to Job # 10964 online at www.cherokee-cnts.com

 

Cherokee Nation Technology Solutions (CNTS) provides technical support services and project support personnel to its defense and civilian agency clients. CNTS specializes in locating hard to find candidates for rapid response requests throughout the country. It provides a tailored management approach for complex government programs and disciplines including information technology, science, engineering, construction, research & development, facilities management, program management, and mission support. Wholly owned by the Cherokee Nation, CNTS is part of the Cherokee Nation Businesses family of companies.

 

About

 

If you’d like more information about your EEO rights as an applicant under the law, please visit the following two sites

 

We are an equal opportunity/affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, protected Veteran status, gender identity and sexual orientation.

 

http://www.eeoc.gov/employers/upload/poster_screen_reader_optimized.pdf

 

http://www.dol.gov/ofccp/regs/compliance/posters/pdf/OFCCP_EEO_Supplement_Final_JRF_QA_508c.pdf

 

If you are an individual with a disability and require a reasonable accommodation to complete any part of the application process, or are limited in the ability or unable to access or use this online application process and need an alternative method for applying, you may e-mail CNB.Compliance@cn-bus.com for assistance. This email address is for accommodation requests only and cannot be used to inquire about the application process or status.

 

For Pay Transparency Non Discrimination provision, click here: https://www.dol.gov/ofccp/pdf/pay-transp_formattedESQA508c.pdf

Seniority Level

Mid-Senior level

Industry

  • Defense & Space
  • Research
  • Biotechnology

Employment Type

Full-time

Job Functions

  • Project Management
  • Information Technology

Read the full job description

Scientist Drug Product Development

Date Posted:
3/25/2017

GSK

MD

Basic Qualifications

 

  • Degree in Chemistry, Biology, Biochemistry, Pharmaceutical Sciences, or related scientific field. PhD with 0+ years of experience, or MS with 3+ years of experience, or BS with 6+ years of experience
  • A good understanding of vaccine formulation science, freeze-drying technologies and key analytical assays is required.
  • Knowledge about physical characterization of the vaccine formulation using high-end instrumentation is a plus, such as, HPLC/UPLC (Empower), Fluorescence, FRET, FTIR, DLS, DSC, etc.
  • Ability to effectively work and perform within a team of dedicated scientists is essential.
  • Must be able to solve complex problems through analytical thinking to identify and understand alternatives using knowledge gained through formal education, experience and sound judgment.
  • Must have the ability to work with cross-functional teams and communicate effectively.
  • Experience in technology transfer and scale-up of drug product processes is a plus.
  • Excellent written and oral skills are a must

     

Preferred Qualifications

 

N/A

 

Details

 

The Scientist is expected to design and execute scientific studies in support of technical programs as they progress from early development into Phase I/ II, Phase III, technology transfer and process performance qualification at the intended commercial site.

 

Responsibilities

 

  • Designs and executes specific development projects under limited direction.
  • Independently responsible for the conception, design, implementation, and interpretation of scientific and technical data to support TRD Drug Product (DP) projects.
  • Collaborates with senior scientific staff to design, implement, and interpret the data from development projects.
  • Makes sound scientific/technical and business decisions based on a balance of data, analysis and experience.
  • Functions effectively as a core team member on multiple concurrent projects and leads small projects and established work processes.
  • Solves complex problems through collaborations with others, taking a new perspective on existing solutions.
  • Provides guidance to new team members and acts as a resource for colleagues with less experience.
  • Generates strong relationships in the area of technical development with high quality partners beneficial to the organization, both internally and externally, to strengthen development/implementation of new methods/technologies.
  • Prepares and presents scientific data within Technical R&D
  • Authors and reviews technical protocols and reports in support of various project development stages.
  • Utilizes knowledge of drug development process to meet regulatory requirements appropriate for stage of development.
  • Communicates effectively within TD and with external stakeholders.

     

Contact Information

 

You may apply for this position online by selecting the Apply now button.

 

If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK HR Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).GSK is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.

 

Important notice to Employment businesses/ Agencies

 

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

 

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit GSK’s Transparency Reporting

Seniority Level

Mid-Senior level

Industry

  • Pharmaceuticals

Employment Type

Full-time

Job Functions

  • Research
  • Analyst
  • Information Technology

Read the full job description

Scientist I

Date Posted:
3/25/2017

Leidos

MD

Leidos Biomedical Research, Inc. (LBRI), a wholly owned subsidiary of Leidos, operates the Frederick National Laboratory for Cancer Research (FNLCR). FNLCR is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI). It is the only FFRDC dedicated to biomedical research. Through its status as an FFRDC, FNLCR provides NCI and others with a unique national resource to accelerate the development and delivery of effective preventive, diagnostic, and therapeutic products for cancer and AIDS.

The breadth of FNLCR’s activities spans the research and development spectrum, including investigator-initiated, hypothesis-driven research into cancer and AIDS; advanced technology programs focused on genetics and genomics, proteins and proteomics, imaging, nanotechnology, bioinformatics, and laboratory animal sciences; clinical operations in support of NCI and National Institute of Allergy and Infectious Diseases (NIAID)-sponsored clinical trials, as well as NCI drug discovery and development efforts; and management and operations of biopharmaceutical development and manufacturing programs under current Good Manufacturing Practice conditions for NCI and NIAID. Administrative, procurement, financial, safety, and facilities support is provided to these R&D activities through state-of-the-art business processes. LBRI has approximately 1,900 employees and manages an annual operating budget of approximately $450M.

 

For more information about Leidos Biomedical Research Inc., please visit our webpage at http://www.leidosbiomed.com/

 

Program Description

 

The Strategic Pilots Incubator (SPI) is responsible for the development and management of a portfolio of exploratory projects that are inherently multidisciplinary that impact cancer research and treatment. Projects aim to analyze the complex interactions in tumor cells and tissues and model systems, blending the best of new physics and engineering based advances with established technologies enabling new opportunities for deeper understanding of tumor biology and cancer progression. Using the latest tools in understanding human performance under stressful conditions can be used to understand and hopefully mitigate the toxic effects of cancer therapy for the patient.

 

Job Description

 

This position description does not represent a current opening but may be used to identify candidates with skills and experience for positions within Leidos Biomedical Research that frequently become available. Candidates who express an interest may be considered for future positions at Leidos Biomedical Research.

 

We are currently recruiting for an experienced biomedical engineer or scientist to support a newly established High Content Pathology Facility at the Frederick National Laboratory for Cancer Research. The new facility will revolve around tissue and single cell analysis, including circulating tumor cells, with the newly acquired Helios Imaging Mass Cytometer, as well as single cell sequencing. We are looking for a self-motivated and proactive individual interested in a cutting-edge and developing technology. The successful candidate will be taking on a pivotal role in the set up and running of the new High Content Pathology Facility. Subsequent to onsite training, candidates will be expected to be skilled in single cell imaging analysis, CyTOF mass cytometry and to develop and implement different applications of this technology.

 

The Scientist I will be responsible for: 1) Setting up and technically validating a single cell analysis laboratory at FNLCR, 2) Developing software and macros for running instrumentation, 3) the daily management and operation of the imaging system and CyTOF, 4) establishing standardized operating procedures (SOP), 5) assisting scientists in experimental design and setup, 6) setting up and maintaining an antibody bank and reagent base, and 7) data analysis.

 

Basic Qualifications

 

Qualifications:

 

  • Possession of a PhD degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) in Biomedical Science, Physical Science, Engineering, Health Care Informatics or related field or eight (8) years equivalent experience in lieu of degree.
  • Foreign degrees must be evaluated for U.S. equivalency
  • No work experience beyond the doctorate education is required for appointment at this level; however, some candidates may have had one or more years of postdoctoral research and training.
  • Strong bioengineering background with expertise in handling and analyzing large data sets including imaging data, genomic, and digital histopathology
  • Experience in microscopy and image acquisition/analysis
  • Proficiency in R and/or Python programming
  • Proficiency with Microsoft Office including Excel
  • Ability to learn new techniques and troubleshoot assays

     

Preferred Qualifications

 

  • Experience with antibody assay development
  • Prior experience with mass cytometry or flow cytometry
  • Experience with tissue and blood sample handling
  • Advantageous skills: immunocytochemistry (ICC) and immunohistochemistry (IHC) techniques
  • Familiar with usage of a Laboratory Information Management System (LIMS)

     

Leidos Overview

 

Leidos is a global science and technology solutions leader working to solve the world’s toughest challenges in the defense, intelligence, homeland security, civil, and health markets. The company’s 33,000 employees support vital missions for government and commercial customers. Headquartered in Reston, Virginia, Leidos reported pro forma annual revenues of approximately $10 billion for the fiscal year ended January 1, 2016 after giving effect to the recently completed combination of Leidos with Lockheed Martin's Information Systems & Global Solutions business (IS&GS). For more information, visit www.Leidos.com. The company’s diverse employees support vital missions for government and commercial customers. Qualified women, minorities, individuals with disabilities and protected veterans are encouraged to apply. Leidos is an Equal Opportunity Employer. Scientist / Research & Development

Seniority Level

Associate

Industry

  • Defense & Space
  • Information Technology and Services
  • Renewables & Environment

Employment Type

Full-time

Job Functions

  • Research
  • Analyst
  • Information Technology
 

Read the full job description

Scientist Microbiology

Date Posted:
3/25/2017

BD

MD

We are currently seeking a high-potential Senior Scientist with biological and engineering skills who can work within a multi-functional team to contribute to the development of automated solutions for the evolving clinical microbiology laboratory. Candidates for this lab-based position will have excellent skills in the design, execution, interpretation and presentation of laboratory experiments with minimal supervision and demonstrated learning agility. They will have excellent interpersonal and communication skills and enjoy working in a team environment. A basic understanding of product development and microbiology is desirable.

 

Job Description

 

We are currently seeking a high-potential Scientist with biological and engineering skills who can work within a multi-functional team to contribute to the development of automated solutions for the evolving clinical microbiology laboratory. Candidates for this lab-based position will have excellent skills in the design, execution, interpretation and presentation of laboratory experiments with minimal supervision and demonstrated learning agility. They will have excellent interpersonal and communication skills and enjoy working in a team environment. A basic understanding of product development and microbiology is desirable.

 

The successful candidate will work within the R&D microbiology team to develop, integrate and test diagnostic capabilities as part of an integrated automated platform for use in a clinical microbiology lab. In a team environment, she/he will work in the areas of specimen processing, pathogen detection, isolation, identification, and susceptibility testing of microorganisms in an automated environment, with responsibilities for the design and execution of experiments, maintaining technical data, data interpretation and generating reports. She/he will be required to communicate information and ideas clearly and effectively within a multidisciplinary group at various levels of the business.

 

Responsibilities

 

  • Works cross-functionally with a number of disciplines and departments (microbiologist, chemists, engineers, marketing, service, etc. ) to develop concepts and designs to meet the needs of a clinical microbiology lab. +
  • Works with a development group to develop and/or test breadboard designs.
  • Collaboratively performs testing on prototype instruments and execute subsequent formal validations.
  • Develops protocols and experimental procedures to address issues or evaluate potential designs.
  • Writes reports, specification or documents related to these efforts.
  • Prepares procedures, write technical reports, publish research papers, and make recommendations based on their research findings. - Innovates novel concepts, approaches, and solutions for addressing clinical microbiology needs .
  • Conceives of and documents intellectual property within the scope of the role.
  • Engages in collaborative efforts with academic, hospital and other external organizations. May have responsibility for managing third-party relationships.
  • Participates in and contribute to other programs in the business as requested.

     

Requirements

 

  • Bachelor’s degree required in the life sciences or biomedical engineering and 5 years related experience is required.
  • Candidates with an advanced degree are preferred. A PhD with postdoctoral experience is preferred.
  • Successful candidate will have a demonstrated aptitude for solving problems involving biological and instrumented or automated platforms.
  • Experience with data storage, processing and analysis is desirable.
  • The ideal candidate will have experience in a multidisciplinary development group with demonstrated communication and problem solving skills.
  • An aptitude for creative approaches to solving bio-mechanical problems is desired.

     


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Online Neuroscience Community Specialist

Date Posted:
3/25/2017

Society for Neuroscience

DC

Position Description:
The Society for Neuroscience (SfN) is searching for a Community Specialist who will be responsible for the growth of the community and discussion areas of SfN's learning and discussion website, Neuronline. This role will work with other programmatic departments to help facilitate the growth of smaller communities, along with evolving the strategy and initiatives within our digital community for the benefit of our members. The Specialist must have excellent communication skills, have knowledge of the field, and interest in social media. This would be ideal for a candidate with a science background that has an aptitude for online technology and communication.

Essential Job Functions:
Member Engagement/Online Community Management

  • Coordinate and participate in the development and implementation of strategies to increase member engagement on the Neuronline community and discussion site.
  • Develop and grow SfN programs to encourage member engagement.
  • Serve as a neuroscience subject matter expert to cultivate community for SfN members, and use that neuroscience expertise to seed conversations and connect members with like interests to one another.
  • Cultivate relationships with SfN staff "moderators" (internal SfN staff who manage society programs), helping to grow Neuronline's programmatic communities.
  • Lead monitoring of member engagement on the Neuronline community site, providing regular data, reports, and analysis on member participation and activity.
  • Lead monitoring of member discussions taking place on comment threads and in the forums.
  • Coordinate with staff from other SfN departments to integrate discussion of the SfN annual meeting, The Journal of Neuroscience, eNeuro, and other content into the forums.

Marketing/Communications

  • Lead smooth planning and implementation of Neuronline-related promotional activities and events at the SfN annual meeting in consultation with SfN's communication and marketing departments.
  • Lead the brainstorming for annual meeting and year-round marketing initiatives for Neuronline forums, working closely with communication and marketing departments.

Technology

  • Serve as first responder to any technical problems that arise within the forums, working with the platform vendor and internal technical support staff.
  • Become an expert in the community/discussion software, Discourse.
  • Learn Sitecore, the Content Management System (CMS), to enter content (written articles, video, audio) and set up pages for the Neuronline website.
  • Work in the CMS to review and troubleshoot content prior to it going live on Neuronline.

Content Development

  • Write and edit content and interview scientific experts and members as needed.
  • Draft marketing text to be distributed through SfN's e-newsletter, the SfN website,N communications vehicles

Minimum Requirements:
Education and Experience:

  • Bachelor's degree in Neuroscience or other relevant field required; Master's degree or PhD preferred
  • Experience with science communication.
  • Basic understanding of publishing online content, and ability to quickly learn new software; HTML and content management experience preferred
  • Experience facilitating on-line or in-person group discussion

Preferred Qualifications:

  • Excellent oral, written, and interpersonal communication skills.
  • Ability to multitask and set priorities, take initiative, and work within a collaborative team environment.
  • Able to plan and execute tasks, on schedule and with attention to detail.
  • Strongly proficient with Microsoft Office applications, and Internet research.
  • Functional ability in CSS considered a strong asset.
  • Experience working in Content Management Systems considered a strong asset.
  • Ability to learn and master an online community management system.
  • Strong organizational and project management skills with the ability to coordinate a diverse set of activities.

Our generous benefits package includes: medical, dental, disability and life insurance; flexible spending accounts, two retirement plans with employer matching and nonmatching contributions; 12 days of paid vacation, 12 days of paid sick leave, with additional personal leave and 10 paid holidays; gym membership reimbursement; and tuition reimbursement.

To Apply:
If this is you and you are eager to make meaningful contributions to a highly relevant and important mission, please submit a cover letter with your salary requirements and a copy of your resume for consideration online:https://sfncareers.applicantpro.com/jobs/503896.html Applications without cover letters will not be considered.

The Society for Neuroscience is wholly dedicated to recruiting, developing, and retaining a diverse group of talented people. We are committed to provide equal opportunities to all employees and applicants without regard to race, color, religion, gender, national origin, age, disability, sexual orientation, gender identity, or other protected criteria, in accordance with applicable law and we welcome Veteran applicants.

 

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Associate Director of Programs

Date Posted:
3/25/2017

Biofrontiers Institute

CO

Position Description:
At the University of Colorado BioFrontiers Institute, researchers from the life and physical sciences, computer science, and engineering work together to uncover new knowledge at the frontiers of science, and partner with industry to make their discoveries relevant. The Institute integrates faculty members from ten academic departments, facilitating their work across disciplines.
Take your career as a gifted administrator in higher education, science or engineering to the next level in this vital and challenging role working with Nobel laureate institute director, Tom Cech.

Responsibilities:

  • Leading a staff of over 20 people, periodically assessing the Institute's needs and developing strategies for positioning our staff for success.
  • Supporting BioFrontiers' leadership by advising them on strategic problem solving and planning, and implementing those plans.
  • Assessing inquiries directed to the Director and Chief Scientific Officer, determining the proper course of action and delegating to the appropriate individual.
  • Overseeing programs and strategic initiatives supporting our research community, and reporting results back to the Director and leadership team.
  • Serving as a key connection point to our partners across the university, and some key external partners.
  • Working with our Director of Operations & Finance to evaluate the effectiveness of current and proposed spending for programs and operations.

What we can offer:
Base salary for this position will be competitive and market-driven, and willdepend upon relevant background and experience. In addition, the University of Colorado offers excellent benefits, including medical, dental, retirement (with a 2-for-1 employer match), generous paid time off, tuition benefit and RTD ECO Bus Pass. The University of Colorado Boulder is one of the largest employers in Boulder County and offers an inspiring higher education environment. Learn more about the University of Colorado Boulder.

Qualifications:

What we require:

  • Bachelor's degree from an accredited institution, preferably in a scientific or engineering discipline.
  • 5 years of experience in a leadership role enabling a large team.

What you will need:

  • Outstanding managerial and interpersonal skills.
  • Proven track record of effective interaction with senior management/leadership.
  • Ability to toggle easily between big picture vision and details of implementation.
  • Ability to tackle large non-linear problems and track progress.
  • Ability to understand a range of perspectives and motivations.
  • Ability to build and maintain trust with multiple and diverse stakeholders.
  • Ability to, extract, distill, contextualize and communicate key information quickly, both verbally and in writing.
  • The capacity to enjoy a high level of responsibility and the opportunity to enable others.

What we'd like you to have:

  • Scientific or engineering background.
  • Advanced degree in science or engineering (PhD preferred).
  • At least one year -- preferably 5 years or more -- working in a higher education setting.
  • 2 years of experience in bioscience or biotech.
  • 5 years of experience in strategic planning and implementation.

Preferred qualifications may be used to further reduce the pool of applicants to those who are most highly qualified.

To Apply:
Please apply by March 28, 2017
If you have technical difficulties submitting application information, please contact the CU Careers help desk atcucareershelp@cu.edu. All other job related inquiries should be directed to the posting contact for this posting.

Application Materials Required: Cover Letter, Resume/CV Application Materials Instructions: To apply, please submit the following materials AS ONE DOCUMENT/PDF to this posting at www.cu.edu/cu-careers:

  1. A current resume.
  2. A cover letter that specifically addresses how your background and experience align with the requirements, qualifications and responsibilities of the position.

Please name your document as follows: First-Last-Resume-CL-08890.
During upload, please indicate the type of document to ensure accurate submission.


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Data Scientist

Date Posted:
3/22/2017

Booz Allen Hamilton

VA

    • USA, VA, McLean (8283 Greensboro Dr, Booz)
  • Booz Allen Hamilton has been at the forefront of strategy and technology for more than 100 years Today, the firm provides management and technology consulting and engineering services to leading Fortune 500 corporations, governments, and not-for-profits across the globe. Booz Allen partners with public and private sector clients to solve their most difficult challenges through a combination of consulting, analytics, mission operations, technology, systems delivery, cybersecurity, engineering and innovation expertise.

     

    Data Scientist

    So you want to be a Data Scientist?

     

    -Are you innately curious, a natural born problem solver, a contrarian or a risk taker?

    -Do you want to solve complex, challenging problems?

    -Do you want to have fun while doing so?

    -Do you want to work alongside others who are passionate about using data science to change the world?

     

    Booz Allen Hamilton is no longer just a consulting firm. We offer an environment in which you can create and deploy data-driven tools while serving as a trusted advisor to your clients. We solve cutting-edge commercial and government problems through research, development, and collaboration among teams working with leading edge technology. Our Strategic Innovation Group offers the best of both worlds: a start-up environment with the backing of an established consulting firm. You will be met with a 100-year history of success and a firm-wide belief that our team should lead the way in innovation by being disrupters and thought leaders in data science.

     

    Our Data Science team: In this role, you will join a diverse, collaborative, and ever-growing data science team. You will work alongside highly-skilled practitioners, including a master-class Kaggle competitor, a member of the Apache Software Foundation, and nationally recognized data science thought leaders with coverage in WSJ, HBR, and many others. You will deliver intellectual capital and solutions that enable our clients to derive the maximum value from their data while solving our clients most pressing business needs.

     

    A day in the life what our Data Scientists do:

    -Tap into the firms consulting roots to define business problems while manipulating data, developing analytical solutions, and executing models

    -Identify new opportunities to further apply advanced analytics solutions with our existing clients

    -Work across all of our markets with private and public sector clients in Energy, Financial Services, Life Sciences (Health), and Defense

    -Pioneer and champion data science for social good while working with national museums, international organizations and non-profits

    -Enhance the diversity of the firm by helping to attract, develop, and retain our existing talent

     

    This position is located in Washington, DC, Boston, MA, San Diego, CA, Houston, TX, or New York, NY.

     

    Basic Qualifications:

    -2 years of experience with advanced data analytic techniques, including data mining, machine learning, statistical analysis, and Natural Language Processing

    -1 year of experience with programming in an object-oriented programming language, including Java or Python

    -Experience in working with massive data sets, including structured and unstructured with at least 1 prior engagement involving data gathering, data cleaning, data mining, and data visualization

    -Ability to show a proven track record of weaving data and analysis into a compelling format that is client- and solutions-driven and easily digestible resulting in client approval

    -Ability to obtain a security clearance

    -BA or BS degree

     

    Additional Qualifications:

    -Experience with scientific research processes and bioinformatics, health and analytical tools related to genomics, medical imaging, phenotypic, or related data

    -Knowledge of government-funded research processes and initiatives

    -Experience with an object-oriented programming language, including Java or Python

    -Experience with articulating the overall story derived from data and analysis and explaining complex analyses and themes to non-technical and technical audiences

    -Knowledge of advanced data analytic techniques, including data mining, machine learning, statistical analysis, and Natural Language Processing

    -Ability to show a track record of solving large, complex problems

    -BA or BS degree in Statistics, Mathematics, Operations Research, EE, CS, or related fields preferred; MA or MS degree in Statistics, Mathematics, Operations Research, Biology, Bioinformatics, Biomedical Engineering, Genetics, Neuroscience, or similar health-related fields a plus; PhD degree in Biomedical Engineering, Bioinformatics, Biology, Genetics, Neuroscience, or related fields a plus

     

    Clearance:

    Applicants selected will be subject to a security investigation and may need to meet eligibility requirements for access to classified information.

     

    Integrating a full range of consulting capabilities, Booz Allen is the one firm that helps clients solve their toughest problems. by their side to help them achieve their missions.  Booz Allen is committed to delivering results that endure.

     

    We are proud of our diverse environment, EOE, M/F/Disability/Vet.


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Biological Scientist microbiology, molecular biology

Date Posted:
3/22/2017

a-tek

MD

Job description
Job Description
Clearance Level Needed: Requires U.S. Citizenship or Green Card Holder. Individual selected will be subject to a background investigation and must meet eligibility requirements for access to sensitive information.
Position Description
This position will be responsible for performing non-research molecular testing to rapidly identify and characterize potential pathogenic bacterial and viral threat agents.
Ensures incoming biological samples are processed and triaged maintaining chain of custody. Performs and interprets a variety of specialized tests and strains, detection, and identification of pathogenic microorganisms.
Prepares written and oral reports, answer questions, troubleshoot and make recommendations to the supervisor for inclusion in comprehensive reports on test findings.
Maintains and operates equipment including performing calibrations, adjustments, and to operate equipment and instruments properly and in a safe manner.
Participates in cross training related to bioterrorism and other public health emergencies.
Additionally, will be responsible for maintaining knowledge and skills related to position and program and to carry out all procedures in accordance to proper handling and storage of various biological materials.
Individual must be available 24/7/365 to respond in case of emergency.
Rotating weekends and some holidays are required.
Qualifications
Ph.D. or Master’s degree from an accredited university in microbiology, molecular biology or related course work in biological sciences, and REQUIRES at least one year of post-graduate laboratory bench experience, utilizing real time polymerase chain reaction (PCR) technology, ELISA, aseptic techniques and biological assays, and at least one year of experience serving as a Senior Scientist or Team Leader of a laboratory team/project. Bachelor’s degree from an accredited university requires four years of laboratory bench experience, including at least one year of experience as a Team Leader/Senior Scientist (total four years’ experience). BSL-3 experience is desirable.
RESUME SUBMISSION REQUIREMENTS: 1. Submission MUST include your Salary requirement (either as specific amount or acceptable range).
A-TEK, Inc. is not a recruiting agency and will not disclose any of your personal information to any outside party.


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Regulatory Health project manager

Date Posted:
3/22/2017

FDA

MD

Job description
Summary
Job Overview
Become a part of the Department that touches the lives of every American! At the Department of Health and Human Services (HHS) you can give back to your community, state, and country by making a difference in the lives of Americans everywhere. It is the principal agency for protecting the health of citizens. Join HHS and help to make our world healthier, safer, and better for all Americans.
The Center for Tobacco Products (CTP) of the Food and Drug Administration (FDA) is responsible for implementing the Family Smoking Prevention and Tobacco Control Act. This law gives FDA authority over tobacco products by adding a new chapter to the Food, Drug and Cosmetic Act. The Tobacco Control Act gives FDA the authority to regulate tobacco products and manufacturers based on the best available science and CTP is responsible for both assessing and fostering that science-base. CTP's actions have significant public health and consumer protection impact, and are among the most important issues faced by the Agency in its long and distinguished history.
This DHHS Position meets the criteria in OMB M-17-17 and is exempt from the hiring freeze.
This position is located in the Department of Health and Human Services (DHHS), Food and Drug Administration (FDA), Center for Tobacco Products (CTP), Office of Science (OS), Silver Spring, Maryland.
This vacancy is also being announced concurrently with vacancy announcement FDA-CTP-17-MP-1930389SW under merit promotion procedures. Please review that announcement to see if you are eligible for consideration under merit promotion procedures.
NOTE: Applicants must apply separately for each announcement in order to be considered.
Who May Apply: Open to all United States Citizens.
Additional selections may be made within the same geographical area FDA-wide.
Duties
Perform library and document search of technical and scientific publications regarding regulated tobacco products and projects.
Monitor the status of all projects, and serves as the primary point of contact.
Work with the team leader and branch chief to resolve both internal and application and project related problems.
Coordinate and monitor the scientific and technical review of routine submissions and projects.
Prepare letters to applications regarding administrative and regulatory issues based on input from review staff.
Prepare minutes of internal applicant meetings.
Travel Required
Occasional Travel
Travel estimated at 2%-Domestic/International
Relocation Authorized
No
Job Requirements
Key Requirements
U.S. Citizenship is required.
Only experience gained by closing date announcement will be considered.
One year probationary period may be required.
Qualifications
Basic Requirements for GS-601 Regulatory Health Project Manager:
Have successfully completed a full four-year course of study at an accredited college or university leading to a bachelor's or higher degree with a major study in an academic field related to health sciences or allied sciences appropriate to the work of the position.
In addition to meeting the basic requirement for the Regulatory Project Health Manager, GS 601-07/09, you must meet the following.
Gs-07
Have one year of specialized experience, equivalent to the GS-05 level in the Federal service, in applying basic scientific principles to carry out assignments and projects; working with and organizing a team to accomplish a variety of activities; and providing technical assistance to resolve program problems, questions, and unusual situations.
OR
Have a one year of graduate level education from an accredited college and/or university.
OR
Have a bachelor's degree as described in the Basic Qualification Requirements above and meet Superior Academic Achievement (S.A.A.) criteria. S.A.A. is based on (1) class standing, (2) grade-point average, or (3) honor society membership. Class standing -- Applicants must be in the upper third of the graduating class in the college, university, or major subdivision, such as the College of Liberal Arts or the School of Business Administration, based on completed courses. Grade-point average (G.P.A.) -- Applicants must have a grade-point average of: 3.0 or higher out of a possible 4.0 ("B" or better) as recorded on their official transcript, or as computed based on 4 years of education, or as computed based on courses completed during the final 2 years of the curriculum; or 3.5 or higher out of a possible 4.0 ("B+" or better) based on the average of the required courses completed in the major field or the required courses in the major field completed during the final 2 years of the curriculum. Grade-point averages are to be rounded to one decimal place. For example, 2.95 will round to 3.0 and 2.94 will round to 2.9. Election to membership in a national scholastic honor society -- Applicants can be considered eligible based on membership in one of the national scholastic honor societies. These honor societies are listed by the Association of College Honor Societies.
OR
Have a combination of the required experience and education for this grade level.
Gs-09
Have one year of specialized experience, equivalent to the GS-07 in the Federal service, in applying basic scientific principles to carry out assignments; leading and organizing a team to accomplish a variety of activities; and providing technical guidance to resolve program problems, questions, and unusual situations.
OR
Have two full years of progressively higher level graduate education leading to a master's degree or equivalent graduate degree in a field that is directly related to Health Sciences or Allied Sciences appropriate to the work of this position.
OR
Have a combination of the required experience and education for this grade level.
You must submit an official transcript, unofficial transcript, or a list including courses, grades earned, completion dates, and quarter and semester hours earned. If you are using education completed in foreign colleges or universities to meet the qualification requirements, you must show that the education credentials have been evaluated by a private organization that specializes in interpretation of foreign education programs and such education has been deemed equivalent to that gained in an accredited U.S. education program. For further information, click on foreign education.
Conditions Of Employment
Security and Background Requirements: Appointment will be subject to the applicant's successful completion of a background security investigation. Failure to successfully meet these requirements may be grounds for appropriate personnel action. If hired, a background security reinvestigation or supplemental investigation may be required at a later time. Applicants are also advised that all information concerning qualifications is subject to investigation. False representation may be grounds for non-consideration, non-selection or appropriate disciplinary action.
E-Verify: If you are selected for this position, the documentation that you present for purposes of completing the Department of Homeland Security (DHS) Form I-9 will be verified through the DHS "E-Verify" System. Federal law requires DHS to use the E-Verify System to verify employment eligibility of all new hires, and as a condition of continued employment obligates the new hire to take affirmative steps to resolve any discrepancies identified by the system. The U.S. Department of Health and Human Services is an E-Verify Participant.
Direct Deposit: All Federal employees are required to have Federal salary payments made by direct deposit to a financial institution of their choosing.
Pre-employment physical required: No
Drug testing required: No
License required: No
Mobility agreement required: No
Immunization required: No
Incentives may be authorized; however, this is contingent upon funds availability. If authorized, certain incentives will require you to sign a service agreement to remain in the Federal government for a period of up to 3 years. Note: This statement does not imply nor guarantee an incentive will be offered and paid. Incentives include the following: student loan repayment, superior qualifications appointment, creditable service for annual leave for prior non-federal work experience or prior uniformed military service, etc.
Bargaining Unit Position: Yes
All qualification requirements must be met by the closing of the announcement.
Please be advised that this position will be subject to FDA's prohibited financial interest regulation and may require the incumbent of this position to divest of certain financial interests. Applicants are advised to seek additional information on this requirement from the hiring official before accepting this position.
Security Clearance
Q - Sensitive
Additional Information
What To Expect Next
Once the online questionnaire is received you will receive an acknowledgement email that your submission was successful. The most highly qualified candidates will be referred to the hiring manager for further consideration and possible interview. We expect to make a selection within 45 days of the closing date of this announcement. Once this process is completed, you will be notified of your status via e-mail.
Benefits
The Federal Government offers a comprehensive benefits package!
Explore the major benefits offered to most Federal employees at https://www.usajobs.gov/Help/working-in-government/benefits/.
Other Information
If you are serving, or have served in the last 5 years (from the close of this announcement) as an Executive Branch political, Schedule C, or Non-career SES appointee, HHS/FDA may be required to obtain approval by the Office of Personnel Management (OPM) prior to beginning employment.
You can find out if you have held one of these appointment types by looking at your Standard Form 50s in your Electronic Official Personnel Folder (eOPF), in Section 5 where the legal authorities are listed. If you have served or are currently serving, you must provide a copy of your SF-50, Notification of Personnel Action, documenting this appointment. In addition, you will be required to respond to the question in the assessment and certify your responses to the questionnaire.
If you are a veteran with preference eligibility and you are claiming 5-points veterans' preference, you must submit a copy of your DD-214 (Member Copy #4) or other proof of eligibility. If you are claiming 10-point veterans' preference, you must also submit an SF-15, "Application for 10-Point Veterans' Preference" plus the proof required by that form. For more information on veterans' preference see http://www.usajobs.gov/Veterans.
Males born after December 31, 1959 must be registered or exempt from Selective Service (see http://www.sss.gov).
For information on "People with Disabilities" please visit http://opm.gov/disability/PeopleWithDisabilities.asp
Career Transition Program: This program applies to Federal workers whose positions have been deemed "surplus" or no longer needed, or an employee who has been involuntarily separated from a Federal service position within the competitive service. To receive selection priority for this position, you must be rated "well-qualified". Well-qualified means eligible applicants whose knowledge, skills, and abilities clearly exceed the minimum qualification requirements of the position. For information on how to apply and what documents to submit as an ICTAP eligible, see: http://www.opm.gov/rif/employee_guides/career_transition.asp
This job originated on www.usajobs.gov. For the full announcement and to apply, visit www.usajobs.gov/GetJob/ViewDetails/466134400. Only resumes submitted according to the instructions on the job announcement listed at www.usajobs.gov will be considered.
Seniority Level
Not Applicable

Industry
Government Administration Program Development
Employment Type
Full-time

Job Functions
Project Management Information Technology


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Microbiologist FDA

Date Posted:
3/22/2017

FDA

MD

Job description
Summary
Job Overview
Become a part of the Department that touches the lives of every American! At the Department of Health and Human Services (HHS) you can give back to your community, state, and country by making a difference in the lives of Americans everywhere. It is the principal agency for protecting the health of citizens. Join HHS and help to make our world healthier, safer, and better for all Americans.
"This HHS Position meets the criteria outlined in OMB M-17-18 and is exempt from the hiring freeze".
Positions Are Located In The Department Of Health And Human Services (DHHS), Food And Drug Administration (FDA) In Montgomery County, MD, And May Be Filled In The Following Centers
Center for Biologics & Evaluation Research (CBER) - Regulates biological products for human use under applicable federal laws, including the Public Health Service Act and the Federal Food, Drug and Cosmetic Act.
Center for Drug Evaluation & Research (CDER) Provide regulatory oversight for investigational studies during drug development and making decisions regarding marketing approval for new drugs.
Center for Devices and Radiological Health (CDRH) - Facilitate medical device innovation by advancing regulatory science, providing industry with predictable, consistent, transparent, and efficient regulatory pathways in devices marketed in the U.S.
Center for Food Safety and Applied Nutrition (CFSAN) - Responsible for the safety of the nation's domestically produced and imported foods, cosmetics, drugs, biologics, medical devices, and radiological products.
Center for Tobacco Products (CTP) - Responsible for implementing the Family Smoking Prevention and Tobacco Control Act to regulate tobacco products and manufactures based on the best available science and for both assessing and fostering that science base.
Office of Regulatory Affairs (ORA)?Inspects regulated products and manufacturers, conducts sample analyses of regulated products and reviews imported products offered for entry into the United States.
National Center for Toxicological Research (NCTR) - is a multi-disciplinary research Center. NCTR conducts scientific research to generate data for FDA decision making, and develops and supports innovative tools and approaches that FDA uses to protect and promote individual and public health.
Center for Veterinary Medicine (CVM) - Conducts research that helps FDA ensure the safety of animal drugs, food for animals, and food products made from animals; and monitors the safety and effectiveness of animal drugs on the market.
NOTE: If you wish to be considered for the Microbiologist position under Merit Promotion procedures, please apply to FDA-CR-17-MP-1926509KC. Please review that announcement to see if you are eligible for consideration under merit promotion procedures.
Who May Apply: Open to all United States Citizens.
Additional selections may be made within the same geographical area FDA-wide.
Duties
Duties Include
As a Microbiologist, GS-0403-11, you will serve as a support scientist performing scientific analysis and research to support work to identify and isolate the microbiological agents, pathogenic bacteria and contaminants from food, drugs, animal drugs, animal feed and/or study the microbiological and immunological basis of the pathogens it the transmission and control of infectious disease that threaten public health.
Plans, develops, and modifies analytical methods to study the distribution of microorganism in natural and manmade environments.
Determines the approach, methods, and procedures to use in order to obtain the information requested, taking into consideration the requirements established by Agency regulations and the Federal law.
Assists in writing comprehensive statistical and analytical reports from major scientific investigations, studies and projects.
Travel Required
Not Required
Relocation Authorized
No
Job Requirements
Key Requirements
U.S. Citizenship is required.
Only experience gained by closing date announcement will be considered.
One year probationary period may be required.
Qualifications
BASIC QUALIFICATION
Basic Requirement for Microbiology Series, 0403 Degree: microbiology; or biology, chemistry, or basic medical science that included at least 20 semester hours in microbiology and other subjects related to the study of microorganisms, and 20 semester hours in the physical and mathematical sciences combining course work in organic chemistry or biochemistry, physics, and college algebra, or their equivalent. OR Combination of education and experience: courses equivalent to a major in microbiology, biology, chemistry, or basic medical science that included courses as shown in A above, plus appropriate experience or additional education.
Additional Requirements
To qualify at the GS-11 level: In addition to meeting the basic requirement, you must have one year of qualifying experience at the GS-9 in the Federal Government obtained in either the private or public sector, performing the following tasks: Performing microbiological analysis and testing; interpreting the findings related to scientific studies; and writing analytical reports from scientific investigations, studies, or projects.
If you are claiming education as any part of your qualifications for this position, you must submit an official transcript, unofficial transcript, or a list including courses, grades earned, completion dates, and quarter and semester hours earned. If you are using education completed in foreign colleges or universities to meet the qualification requirements, you must show that the education credentials have been evaluated by a private organization that specializes in interpretation of foreign education programs and such education has been deemed equivalent to that gained in an accredited U.S. education program. For further information, click on foreign education.
Conditions Of Employment
Security and Background Requirements: Appointment will be subject to the applicant's successful completion of a background security investigation. Failure to successfully meet these requirements may be grounds for appropriate personnel action. If hired, a background security reinvestigation or supplemental investigation may be required at a later time. Applicants are also advised that all information concerning qualifications is subject to investigation. False representation may be grounds for non-consideration, non-selection or appropriate disciplinary action.
E-Verify: If you are selected for this position, the documentation that you present for purposes of completing the Department of Homeland Security (DHS) Form I-9 will be verified through the DHS "E-Verify" System. Federal law requires DHS to use the E-Verify System to verify employment eligibility of all new hires, and as a condition of continued employment obligates the new hire to take affirmative steps to resolve any discrepancies identified by the system. The U.S. Department of Health and Human Services is an E-Verify Participant.
Direct Deposit: All Federal employees are required to have Federal salary payments made by direct deposit to a financial institution of their choosing.
Pre-employment physical required: No
Drug testing required: No
License required: No
Mobility agreement required: No
Immunization required: No
Incentives may be authorized; however, this is contingent upon funds availability. If authorized, certain incentives will require you to sign a service agreement to remain in the Federal government for a period of up to 3 years. Note: This statement does not imply nor guarantee an incentive will be offered and paid. Incentives include the following: moving expenses, recruitment or relocation incentive; student loan repayment, superior qualifications appointment, creditable service for annual leave for prior non-federal work experience or prior uniformed military service, etc.
Bargaining Unit Position: Yes
All qualification requirements must be met by the closing of the announcement.
Financial disclosure statement required: No


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Biologist FDA

Date Posted:
3/22/2017

FDA

MD

Job description
Summary
Job Overview
Become a part of the Department that touches the lives of every American! At the Department of Health and Human Services (HHS) you can give back to your community, state, and country by making a difference in the lives of Americans everywhere. It is the principal agency for protecting the health of citizens. Join HHS and help to make our world healthier, safer, and better for all Americans.
This DHHS Position meets the criteria in OMB M-17-17 and is exempt from the hiring freeze. **
This Position Is Located In The Department Of Health And Human Services (DHHS), Food And Drug Administration (FDA), In Montgomery County, Maryland, And May Be Filled In The Following Centers
Center for Biologics & Evaluation Research (CBER)
Center for Drug Evaluation & Research (CDER)
Center for Devices and Radiological Health (CDRH)
Center for Food Safety and Applied Nutrition (CFSAN)
Center for Tobacco Products (CTP)
Office of Regulatory Affairs (ORA)
National Center for Toxicological Research (NCTR)
Center for Veterinary Medicine (CVM)
This vacancy is also being announced concurrently with vacancy announcement FDA-CR-17-MP-1925111SW under merit promotion procedures. Please review that announcement to see if you are eligible for consideration under merit promotion procedures.
NOTE: Applicants must apply separately for each announcement in order to be considered.
Who May Apply: Open to all United States Citizens.
Additional selections may be made within the same geographical area FDA-wide.
Duties
Plans and conducts studies and investigations concerning biological, chemical, and physical processes that affect biology resources. Modifies and adapts standard techniques, processes, and procedures; assesses, selects, and applies precedents.
Analyzes data, performs scientific tests, and conducts studies on the impact of existing or proposed management or public practices on biology resources. Develops plans for biology projects including estimate of personnel, equipment, materials, and schedules required to carry out plans.
Conducts project analyses and reviews results of studies of investigations. Evaluates the impact of the lasts technological advances in biology on novel studies conducted and on current and future programs. Manages the day-to-day operation of the laboratory, including coordinating research projects and personnel, and ensuring availability of equipment and supplies.
Travel Required
Not Required
Relocation Authorized
No
Job Requirements
Key Requirements
U.S. Citizenship is required.
Only experience gained by closing date announcement will be considered.
One year probationary period may be required.
Official Transcript required.
Qualifications
Basic Qualification Requirements for Biologist, GS-401:
Degree: biological sciences, agriculture, natural resource management, chemistry, or related disciplines appropriate to the position.
OR
Combination of education and experience: Courses equivalent to a major, as shown in A above, plus appropriate experience or additional education.
AND
Specialized experience requirement: In addition to meeting the Basic Qualification Requirement outlined above, you must meet the minimum qualifications below for the Biologist, GS-401-13.
I have at least one year of specialized experience equivalent to the GS-12 grade level in the Federal service, which includes planning and conducting studies and investigations pertaining to biological sciences; performing scientific tests and analyzing results for valid data; evaluating inaccurate data and recommending solutions; and assist with managing the operation of a laboratory.
If you are claiming education as any part of your qualifications for this position, you must submit an official transcript, unofficial transcript, or a list including courses, grades earned, completion dates, and quarter and semester hours earned. If you are using education completed in foreign colleges or universities to meet the qualification requirements, you must show that the education credentials have been evaluated by a private organization that specializes in interpretation of foreign education programs and such education has been deemed equivalent to that gained in an accredited U.S. education program. For further information, click on foreign education.
Conditions Of Employment
Security and Background Requirements: Appointment will be subject to the applicant's successful completion of a background security investigation. Failure to successfully meet these requirements may be grounds for appropriate personnel action. If hired, a background security reinvestigation or supplemental investigation may be required at a later time. Applicants are also advised that all information concerning qualifications is subject to investigation. False representation may be grounds for non-consideration, non-selection or appropriate disciplinary action.
E-Verify: If you are selected for this position, the documentation that you present for purposes of completing the Department of Homeland Security (DHS) Form I-9 will be verified through the DHS "E-Verify" System. Federal law requires DHS to use the E-Verify System to verify employment eligibility of all new hires, and as a condition of continued employment obligates the new hire to take affirmative steps to resolve any discrepancies identified by the system. The U.S. Department of Health and Human Services is an E-Verify Participant.
Direct Deposit: All Federal employees are required to have Federal salary payments made by direct deposit to a financial institution of their choosing.
Pre-employment physical required: No
Drug testing required: No
License required: No
Mobility agreement required: No
Immunization required: No
Incentives may be authorized; however, this is contingent upon funds availability. If authorized, certain incentives will require you to sign a service agreement to remain in the Federal government for a period of up to 3 years. Note: This statement does not imply nor guarantee an incentive will be offered and paid. Incentives include the following: moving expenses, recruitment or relocation incentive; student loan repayment, superior qualifications appointment, creditable service for annual leave for prior non-federal work experience or prior uniformed military service, etc.
Bargaining Unit Position: Yes
All qualification requirements must be met by the closing of the announcement.
Financial disclosure statement required: No
Security Clearance
Public Trust - Background Investigation
Additional Information
What To Expect Next
Once the online questionnaire is received you will receive an acknowledgement email that your submission was successful. The most highly qualified candidates will be referred to the hiring manager for further consideration and possible interview. We expect to make a selection within 45 days of the closing date of this announcement. Once this process is completed, you will be notified of your status via e-mail.
Benefits
The Federal Government offers a comprehensive benefits package!
Explore the major benefits offered to most Federal employees at https://www.usajobs.gov/Help/working-in-government/benefits/.
Other Information
If you are serving, or have served in the last 5 years (from the close of this announcement) as an Executive Branch political, Schedule C, or Non-career SES appointee, HHS/FDA may be required to obtain approval by the Office of Personnel Management (OPM) prior to beginning employment.
You can find out if you have held one of these appointment types by looking at your Standard Form 50s in your Electronic Official Personnel Folder (eOPF), in Section 5 where the legal authorities are listed. If you have served or are currently serving, you must provide a copy of your SF-50, Notification of Personnel Action, documenting this appointment. In addition, you will be required to respond to the question in the assessment and certify your responses to the questionnaire.
If you are a veteran with preference eligibility and you are claiming 5-points veterans' preference, you must submit a copy of your DD-214 (Member Copy #4) or other proof of eligibility. If you are claiming 10-point veterans' preference, you must also submit an SF-15, "Application for 10-Point Veterans' Preference" plus the proof required by that form. For more information on veterans' preference see http://www.usajobs.gov/Veterans.
Males born after December 31, 1959 must be registered or exempt from Selective Service (see http://www.sss.gov).
For information on "People with Disabilities" please visit http://opm.gov/disability/PeopleWithDisabilities.asp
Career Transition Program: This program applies to Federal workers whose positions have been deemed "surplus" or no longer needed, or an employee who has been involuntarily separated from a Federal service position within the competitive service. To receive selection priority for this position, you must be rated "well-qualified". Well-qualified means eligible applicants whose knowledge, skills, and abilities clearly exceed the minimum qualification requirements of the position. For information on how to apply and what documents to submit as an ICTAP eligible, see: http://www.opm.gov/rif/employee_guides/career_transition.asp
This job originated on www.usajobs.gov. For the full announcement and to apply, visit www.usajobs.gov/GetJob/ViewDetails/465651500. Only resumes submitted according to the instructions on the job announcement listed at www.usajobs.gov will be considered.


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Scientist I, RAS 3D cell culture

Date Posted:
3/22/2017

Leidos

MD

Program Description:
The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish National Cancer Institute (NCI) research objectives. The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community. A major focus of the CRTP is the NCI RAS Initiative with the goal to discover new therapeutic interventions against RAS-driven cancers.

Position Description:
The Scientist I will work in support of the Frederick National Laboratory/NCI RAS Initiative in Frederick, Maryland. One of the major objectives of the RAS initiative at the Frederick National Lab for Cancer Research (FNLCR) is to dissect the biology and mechanisms that result in oncogenic signaling KRAS mutant cells in support of drug discovery efforts. The Scientist I using primarily 3D cell culture systems will: 1) work to expand knowledge of RAS signaling pathways, 2) participate in experimental design and to independently conduct experiments in a priority-driven environment, 3) complete projects independently and as part of a team, 4) be responsible for timely updates of the project progress to their supervisor both informally and by formal report writing, 5) generate high-quality peer-reviewed publications, 6) be responsible for formal reporting of data including presentations and/or publications and, and 7) stay abreast of current research techniques and remain knowledgeable in pertinent areas through reading literature and by attending scientific presentations.

To learn more about the RAS Initiative at the Frederick National Lab, please visit: https://www.cancer.gov/research/key-initiatives/ras.
For information regarding Dr. Rachel Bagni, Sr. Scientist, Cancer Research Technology Program, and her lab, please visit: https://www.cancer.gov/research/key-initiatives/ras/screens-assays/model-development.

PLEASE NOTE THAT LEIDOS BIOMEDICAL RESEARCH, INC. CANNOT HIRE J-1 VISA HOLDERS FROM THE NATIONAL INSTITUTES OF HEALTH.

Qualifications:
To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:

PhD in a field related to pharmaceutical science, medicinal chemistry, or chemistry, or in a related discipline from an accredited college or university according to the Council for Higher Education Accreditation (CHEA) appropriate to biomedical research, or eight (8) years of experience in lieu of degree
Foreign degrees must be evaluated for U.S. equivalency
No experience required beyond the educational requirement
Knowledge of cell biology and signal transduction pathways
Ability to perform basic molecular biology experiments both independently and as a part of the RAS team in pursuit of specific research goals and objectives
Knowledge and ability to generate and characterize engineered cell lines used to study oncogenic signaling
Cell culture and cell-based assay development experience
Must be able to obtain and maintain a Security Clearance
Preferred Qualifications:
Candidates with these desired skills will be given preferential consideration:

Background in oncology and experience with in vitro cancer cell models
Experience with 3D cell culture model systems and 3D cell-based assays
Familiarity with the relevant scientific literature
Ability to develop and modify methods and techniques independently
To Apply:
If interested, please apply on-line for position #635379 at http://jobs.leidos.com/ShowJob/Id/1122950/Scientist-RAS-3D-Cell-Culture-(NCI)/


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Research Manager Malaria Global Health Lab

Date Posted:
3/22/2017

University of Maryland

MD

3/19/2017 Research Manager https://umb.taleo.net/careersection/umb_external_staff/jobdetail.ftl 1/3 This is the Jobs Portal for the UNIVERSITY OF MARYLAND, BALTIMORE | HUMAN RESOURCE SERVICES JOBS Job Description The University of Maryland, Baltimore (UMB), Division of Malaria Research (DMR) in the Institute for Global Health is currently seeking a Research Manager. The mission of the DMR is to support global malaria eradication efforts by developing and deploying innovative tools for improved malaria treatment, prevention and surveillance. Clinical and basic science research is supported domestically and throughout the regions with a high burden of malaria. This position is responsible for managing the operations of a research program and providing administrative and technical support to the research activities. This position is responsible for ensuring design, development, documentation and implementation of research procedures and protocols using a variety of complex activities. This position has the authority to formulate, affect, interpret, or implement management policies or operating practices. Benefits Information UMB offers a generous benefits package that includes 22 vacation days, 14 floating and holidays, 15 sick days; comprehensive health insurance and retirement options; and tuition remission for employees and their dependents at any of the University System of Maryland schools. Primary Duties and Responsibilities (Essential Functions) Manage research and administrative activities including training, scheduling, coordinating and delegating work, monitoring and evaluating performance to maximize effectiveness and productivity. Manage laboratory and staffing budget for grants from multiple sources. Create timelines and ensure that activities are being managed to meet key deadlines. Research Manager - (170000FP) 3/19/2017 Research Manager https://umb.taleo.net/careersection/umb_external_staff/jobdetail.ftl 2/3 Ensure quality control and safety compliance, develop policies and procedures, and order supplies for the lab. Identify and address issues and deficiencies and implement effective solutions. Manage the development and execution of project research studies. Revises studies, in consultation with upper management or principal investigator, to meet changing needs and requirements and enforces standards. Foster and support a conducive consultant/client environment, providing business unit and campus representatives with assessment, training, and advisement in research area. Creates a cohesive work team that works collaboratively to achieve unit’s goals. Oversees the recruitment, performance, and training of team members and continually reviews strengths and weaknesses of staff to maintain a well-trained, highly involved, and motivated team. Performs other related duties as assigned. Qualifications Education: Bachelor’s degree. Experience: Six (6) years of experience in research or project management including four (4) years in a relevant specialization. Supervisory: Two (2) years of direct supervision or responsibility for training, work coordination, and monitoring the work of others. Knowledge, Skills, and Abilities Strong writing skills for communications with team members, collaborators and sponsors. Ability to establish goals, structures, and processes necessary to implement a mission and strategic vision. Assumes personal responsibility for all outcomes; makes effective and timely decisions; and learns how to effectively use technology. Maintains productivity and uses knowledge strategies to increase knowledge base. Ability to perform basic accounting and statistical analysis. Ability to effectively communicate both verbal and written thoughts, ideas, and facts. Interprets and understands written information and is able to listen attentively to verbal and non-verbal cues that lead to a deeper understanding. Ability to maintain confidentiality of subjects and information obtained. Leadership, coaching, and team building skills to strengthen and cultivate relationships. Ability to network and interact, as well as support effective partnerships with key groups and individuals. Ability to work cooperatively with others and demonstrates professional, ethical, respectful, and courteous behavior when interacting with others. Demonstrate pleasant and positive interactions with other to meet customer expectations, and provide follow up with customers. Reaches compromise and consensus to influence and negotiate. Remains calm and is able to manage conflict, and works well with a diverse workforce. Approachable style allows others to be open in sharing thoughts and ideas. Able to make independent decisions that are a matter of significance for the unit. Hiring Range: Commensurate with education and experience 3/19/2017 Research Manager https://umb.taleo.net/careersection/umb_external_staff/jobdetail.ftl 3/3 Human Resource Services 410-706-7171 620 W. Lexington Street 3rd Floor Baltimore, MD 21201 The University of Maryland, Baltimore is an Equal Opportunity/Affirmative Action Employer. Minorities, women, protected veterans and individuals with disabilities are encouraged to apply. If accommodations are needed for a disability, please contact Staffing & Career Services at 410-706-2606, Monday – Friday, 8:30am – 4:30pm EST. Maryland Relay can be accessed by dialing 711 (in-state) or 1-800-735-2258. Equal Opportunity/Affirmative Action Employer. Minorities, women, protected veterans, and individuals with disabilities are encouraged to apply. Job Exempt Staff - E3327F Employee Class : Exempt Regular Full Time/Part Time: Full-Time Shift Day Job Financial Disclosure: No Organization Medicine Posting Date Mar 6, 2017 Unposting Date Mar 25, 2017, 11:59:00 PM © 2015-2016 UNIVERSITY OF MARYLAND, BALTIMORE. ALL RIGHTS RESERVED.


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Program Manager Global Health Malaria Research

Date Posted:
3/22/2017

University of Maryland

MD

3/19/2017 Program Manager - Institute for Global Health - Myanmar https://umb.taleo.net/careersection/umb_external_staff/jobdetail.ftl 1/3 This is the Jobs Portal for the UNIVERSITY OF MARYLAND, BALTIMORE | HUMAN RESOURCE SERVICES JOBS Job Description The Division of Malaria Research at the University of Maryland, Baltimore (UMB) Institute for Global Health seeks a Program Manager to ensure the success of the Maryland Global Initiatives Corporation (MGIC) program in Myanmar. The Program Manager will coordinate the daily activities of the program, staff functions, and manage budgetary issues. The Program Manager is responsible to set goals and create tactics in order to achieve programmatic objectives. This position hires and trains staff as needed. ***This position will require up to 10% travel to Myanmar.*** Benefits Information UMB offers a generous benefits package that includes 22 vacation days, 14 floating and holidays, 15 sick days; comprehensive health insurance and retirement options; and tuition remission for employees and their dependents at any of the University System of Maryland schools. Primary Duties and Responsibilities (Essential Functions) Plan and coordinate daily activities of the program in Myanmar including monitoring relationships of outside agencies or subcontractors. Work in collaboration with with senior management to develop, implement and achieve program goals and milestones. Supervise, train, schedule, and evaluate professional and clerical staff. Manage program budget, including approving finances, tracking expenditures, and preparing reports on current finances. Develop appropriate processes and procedures regarding research sample storage, monitoring, and transport between domestic and international sites. Program Manager - Institute for Global Health - Myanmar - (170000FO) 3/19/2017 Program Manager - Institute for Global Health - Myanmar https://umb.taleo.net/careersection/umb_external_staff/jobdetail.ftl 2/3 Ensure that administrative and regulatory requirements regarding human subject research are accurately met, documented, and reported. Coordinate and assist in training programs/capacity development workshops for employees, volunteers, and/or the community. Plan data management and communications strategy for the program. Assist in the coordination and communication between the US and local institutions and implementing partners. Perform other related duties as assigned. Qualifications Education: Bachelor’s degree in related field. Experience: Four (4) years experience in a related field. Supervisory: Two (2) years supervisor, program planning and coordination experience required. Knowledge, Skills, and Abilities Possesses knowledge of best practices in the field as well as all relevant federal, state, and local rules, regulations, and programs/policies for meeting compliance. Ability to establish goals, structures, and processes necessary to implement a mission and strategic vision. Skill in leadership, coaching, and team building in order to strengthen and cultivate relationships. Strategic and analytical thinking skills with an ability to solve problems and make decisions. Ability to prioritize ongoing and new projects, as well as conduct research and gather information. Skill in interpreting and understanding written information and is able to listen attentively to verbal and nonverbal cues that lead to a deeper understanding. Ability to operate current computer systems, including relevant software packages. Ability to prepare and analyze reports. Ability to create and manage a budget. Ability to perform statistical analysis. Ability to network and interact, as well as support effective partnerships with key groups and individuals. Ability to effectively communicate both verbal and written thoughts, ideas, and facts. Ability to schedule, train, supervise, assign work to, and evaluate staff. Ability to work cooperatively with others and demonstrates professional, ethical, respectful, and courteous behavior when interacting with others. Skill in demonstrating pleasant and positive interactions with other to meet customer expectations, and provide follow up with customers. Ability to reach compromise and consensus to influence and negotiate. Ability to remains calm, manage conflict, and works well with a diverse workforce. Hiring Range: Commensurate with education and experience If accommodations are needed for a disability, please contact Staffing & Career Services at 410-706-2606, Monday – Friday, 8:30am – 4:30pm EST. Maryland Relay can be accessed by dialing 711 (in-state) or 1-800-735-2258. Equal Opportunity/Affirmative Action Employer. Minorities, women, protected veterans, and individuals with disabilities are encouraged to apply. Job Exempt Staff - E1431F 3/19/2017 Program Manager - Institute for Global Health - Myanmar https://umb.taleo.net/careersection/umb_external_staff/jobdetail.ftl 3/3 Human Resource Services 410-706-7171 620 W. Lexington Street 3rd Floor Baltimore, MD 21201 The University of Maryland, Baltimore is an Equal Opportunity/Affirmative Action Employer. Minorities, women, protected veterans and individuals with disabilities are encouraged to apply. Employee Class : Exempt Regular Full Time/Part Time: Full-Time Shift Day Job Financial Disclosure: No Organization Medicine Posting Date Feb 28, 2017 Unposting Date Mar 19, 2017, 11:59:00 PM © 2015-2016 UNIVERSITY OF MARYLAND, BALTIMORE. ALL RIGHTS RESERVED.


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Instructor/Assistant Professor Malaria Immunology Research

Date Posted:
3/22/2017

University of Maryland

MD

3/19/2017 Instructor/ Assistant Professor- Institute for Global Health https://umb.taleo.net/careersection/umb_faculty+and+post+docs/jobdetail.ftl 1/3 This is the Jobs Portal for the UNIVERSITY OF MARYLAND, BALTIMORE | HUMAN RESOURCE SERVICES JOBS Job Description The Division of Malaria Research (DMR) within the University of Maryland School of Medicine’s Institute for Global Health (IGH) is recruiting for an Instructor or Assistant Professor, nontenure track, to design and lead clinical trials and epidemiological studies at the DMR’s international site in Malawi. Applicants with interest and qualifications to do so may also contribute to immunological, molecular and genomic aspects of DMR research studies. The faculty appointment will be at the rank of Instructor or Assistant Professor, nontenure track, based on guidelines for faculty appointment at the University of Maryland School of Medicine. The applicant will be expected to obtain a primary appointment in the Department of Pediatrics. This is a fulltime faculty position, preferably to be permanently located at the DMR clinical trials site in Malawi, Expatriate status . Since much of the proposed research involves studies in Malawi, prior experience in working in resource limited settings is strongly preferred. The successful candidate will have experience conducting clinical research, evidence of productivity as demonstrated by publication of completed projects and be interested in pursuing a career in scientific research. The Candidate will engage in collaborative research that draws upon the expertise of scientists from the Division of Malaria Research, the Department of Pediatrics, the Department of Epidemiology and Public Health and the Department of Microbiology and Immunology, affiliated international sites, and other strategic partnerships. Instructor/ Assistant Professor- Institute for Global Health - (170000JD) 3/19/2017 Instructor/ Assistant Professor- Institute for Global Health https://umb.taleo.net/careersection/umb_faculty+and+post+docs/jobdetail.ftl 2/3 Qualifications MD/PhD or PhD degree and appropriate postdoctoral experience in immunology Expertise in infectious diseases cellular immunology Experience supervising students and/or postdoctoral fellows PREFERRED CHARACTERISTICS: Experience in malaria or parasitology research Expertise in B cell immunology is highly desirable Experience conducting research using human field samples Proven success in obtaining research funding with some external funding in place Experience on research projects conducted in lowincome countries Track record of publications in peerreviewed journals The ability to work well in an interdisciplinary and multicultural team Excellent interpersonal skills and a willingness to work with others to overcome problems as and when they arise Ability to provide mentorship to junior colleagues and supervise MSc and PhD students and post –doctoral fellows Excellent written and spoken scientific communication skills For immediate consideration, please send a cover letter and uptodate CV, including names and contact information of three references, by email to: Nichole Harvey Gilliam, Institute for Global Health at the University of Maryland School of Medicine, 685 W. Baltimore St., HSF I, Room 480, Baltimore, MD 21201 nigilliam@som.umaryland.edu. Please reference position number 03314434 when applying. If accommodations are needed, contact Staffing & Career Services at 4107067171, Monday – Friday, 8:30am 4: 30pm EST. Maryland Relay can be accessed by dialing 711 (instate) or 18007352258. The University of Maryland, Baltimore is an Equal Opportunity/Affirmative Action Employer. Minorities, women, veterans and individuals with disabilities are encouraged to apply. 3/19/2017 Instructor/ Assistant Professor- Institute for Global Health https://umb.taleo.net/careersection/umb_faculty+and+post+docs/jobdetail.ftl 3/3 Human Resource Services 410-706-7171 620 W. Lexington Street 3rd Floor Baltimore, MD 21201 The University of Maryland, Baltimore is an Equal Opportunity/Affirmative Action Employer. Minorities, women, protected veterans and individuals with disabilities are encouraged to apply. Job Faculty Organization SOM Centers/Programs/ORCs Posting Date Mar 10, 2017 © 2015-2016 UNIVERSITY OF MARYLAND, BALTIMORE. ALL RIGHTS RESERVED.


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Assistant Professor Global Health Malaria Research

Date Posted:
3/22/2017

University of Maryland

MD

3/19/2017 Assistant/ Assoicate Professor-Institute of Global Health https://umb.taleo.net/careersection/umb_faculty+and+post+docs/jobdetail.ftl 1/3 This is the Jobs Portal for the UNIVERSITY OF MARYLAND, BALTIMORE | HUMAN RESOURCE SERVICES JOBS Job Description The Division of Malaria Research (DMR) within the University of Maryland School of Medicine’s Institute for Global Health (IGH) is recruiting for an Assistant or Associate Professor for malaria research in the area of immunology. Areas of focus can include but are not limited to infant and child immunity to malaria, HIVmalaria coinfection and interactions and the impact of the microbiome on immunological development and responses. Applicants with interest and qualifications to do so may also contribute to molecular and genomic aspects of DMR clinical research studies. The faculty appointment will be at the rank of Assistant Professor or Associate Professor, tenure track both of which will be considered, commensurate with experience and based on guidelines for faculty appointment at the University of Maryland School of Medicine. The applicant will be expected to obtain a primary academic appointment in the Department of Pediatrics. This is a fulltime faculty position based at IGH in Baltimore. The ideal applicant will have evidence of external research support that can be transferred to the institution. Mentored grants would be acceptable but independent funding is preferred. The successful applicant will be expected to establish and maintain a productive, externally funded research program within the Division of Malaria Research (DMR) and in close collaboration with the Immunology Group within the Center for Vaccine Development (the Division and Center are within the Institute for Global Health). The successful applicant will be expected to participate in collaborative research activities with other members of the DMR and to participate in academic and service activities based on standard policies at the University of Maryland School of Medicine. There will be opportunities for teaching and training graduate students, postdoctoral fellows and junior faculty. Assistant/ Assoicate Professor-Institute of Global Health - (170000JE) 3/19/2017 Assistant/ Assoicate Professor-Institute of Global Health https://umb.taleo.net/careersection/umb_faculty+and+post+docs/jobdetail.ftl 2/3 For immediate consideration, please send a cover letter and uptodate CV, including names and contact information of three references, by email to: Nichole Harvey Gilliam, Institute for Global Health at the University of Maryland School of Medicine, 685 W. Baltimore St., HSF I, Room 480, Baltimore, MD 21201 nigilliam@som.umaryland.edu. Please reference position number 03314434 when applying. Qualifications MD/PhD or PhD degree and appropriate postdoctoral experience in immunology Expertise in infectious diseases cellular immunology Experience supervising students and/or postdoctoral fellows PREFERRED CHARACTERISTICS: Experience in malaria or parasitology research Expertise in B cell immunology is highly desirable Experience conducting research using human field samples Proven success in obtaining research funding with some external funding in place Experience on research projects conducted in lowincome countries Track record of publications in peerreviewed journals The ability to work well in an interdisciplinary and multicultural team Excellent interpersonal skills and a willingness to work with others to overcome problems as and when they arise Ability to provide mentorship to junior colleagues and supervise MSc and PhD students and post –doctoral fellows Excellent written and spoken scientific communication skills If accommodations are needed, contact Staffing & Career Services at 4107067171, Monday – Friday, 8:30am 4: 30pm EST. Maryland Relay can be accessed by dialing 711 (instate) or 18007352258. The University of Maryland, Baltimore is an Equal Opportunity/Affirmative Action Employer. Minorities, women, veterans and individuals with disabilities are encouraged to apply. Job Faculty Organization SOM Centers/Programs/ORCs Posting Date Mar 10, 2017 3/19/2017 Assistant/ Assoicate Professor-Institute of Global Health https://umb.taleo.net/careersection/umb_faculty+and+post+docs/jobdetail.ftl 3/3 Human Resource Services 410-706-7171 620 W. Lexington Street 3rd Floor Baltimore, MD 21201 The University of Maryland, Baltimore is an Equal Opportunity/Affirmative Action Employer. Minorities, women, protected veterans and individuals with disabilities are encouraged to apply. © 2015-2016 UNIVERSITY OF MARYLAND, BALTIMORE. ALL RIGHTS RESERVED.


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Senior Scientist Biomedical Engineering

Date Posted:
3/17/2017

BD

MD

We are currently seeking a high-potential Senior Scientist with biological and engineering skills who can work within a multi-functional team to contribute to the development of automated solutions for the evolving clinical microbiology laboratory. Candidates for this lab-based position will have excellent skills in the design, execution, interpretation and presentation of laboratory experiments with minimal supervision and demonstrated learning agility. They will have excellent interpersonal and communication skills and enjoy working in a team environment. A basic understanding of product development and microbiology is desirable.

The successful candidate will work within the R&D microbiology team to develop, integrate and test diagnostic capabilities as part of an integrated automated platform for use in a clinical microbiology lab. In a team environment, she/he will work in the areas of specimen processing, pathogen detection, isolation, identification, and susceptibility testing of microorganisms in an automated environment, with responsibilities for the design and execution of experiments, maintaining technical data, data interpretation and generating reports. She/he will be required to communicate information and ideas clearly and effectively within a multidisciplinary group at various levels of the business.

Responsibilities:

Works cross-functionally with a number of disciplines and departments (microbiologist, chemists, engineers, marketing, service, etc. ) to develop concepts and designs to meet the needs of a clinical microbiology lab. +
Works with a development group to develop and/or test breadboard designs.
Collaboratively performs testing on prototype instruments and execute subsequent formal validations.
Develops protocols and experimental procedures to address issues or evaluate potential designs.
Writes reports, specification or documents related to these efforts.
Prepares procedures, write technical reports, publish research papers, and make recommendations based on their research findings. - Innovates novel concepts, approaches, and solutions for addressing clinical microbiology needs .
Conceives of and documents intellectual property within the scope of the role.
Engages in collaborative efforts with academic, hospital and other external organizations. May have responsibility for managing third-party relationships.
Participates in and contribute to other programs in the business as requested.
Requirements:

Bachelor’s degree required in the life sciences or biomedical engineering and 5 years related experience is required.
Candidates with an advanced degree are preferred. A PhD with postdoctoral experience is preferred.
Successful candidate will have a demonstrated aptitude for solving problems involving biological and instrumented or automated platforms.
Experience with data storage, processing and analysis is desirable.
The ideal candidate will have experience in a multidisciplinary development group with demonstrated communication and problem solving skills.
An aptitude for creative approaches to solving bio-mechanical problems is desired.
Primary Work Location

USA MD - Baltimore


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Senior Scientist Microbiology

Date Posted:
3/17/2017

BD

MD

Becton Dickinson is a world leader in pathogen identification and antimicrobial susceptibility testing in the clinical microbiology laboratory. We are currently seeking a high-potential individual with microbiology skills who can work independently and within a multifunctional team to contribute to the development of automated diagnostics solutions for the evolving clinical microbiology laboratory. The successful candidate will be an innovative biologist/microbiologist or biomedical engineer with a relevant life sciences background and demonstrated experience solving complex biological problems. The successful candidate will be able to effectively transition between manipulating biologicals, consumables and mechanical platforms. Candidates for this lab-based position will have excellent skills in the design, execution, data analysis and interpretation, and presentation of laboratory experiments with minimal supervision and demonstrated learning agility. They will have excellent interpersonal and communication skills and enjoy working in a team environment. A basic understanding of product development, particularly in a regulated clinical environment is desirable.
Job Description

Primary Duties and Responsibilities:

The successful candidate will work within the R&D microbiology team to conceive, develop, integrate and test diagnostic capabilities as part of an integrated automated platform for use in a clinical microbiology lab.

In a team environment, she/he will work in the areas of specimen processing, pathogen detection, isolation, identification, and antimicrobial susceptibility testing of microorganisms, with responsiblities for the design and execution of experiments, maintaining technical data, data analysis and interpretation, and generating reports. She/he will be required to communicate information and ideas clearly and effectively within a multi-disciplinary group at various levels of the business.

The primary responsibilities include:

Provides technical leadership and domain expertise in microbiology to cross-functional project teams aimed at the development of novel infectious disease diagnostics. Works closely with other functions (i.e., Marketing, Operations, Quality, Engineering R&D) to troubleshoot, characterize and resolve needs in existing and nacent technologies.
With minimal oversight, delivers hands-on lab-based experimental contributions toward programs or business objectives. Is highly learning agile, innovative and organized: proficient in executing multiple, simultaneous projects in a time-efficient manner. Independently provides data analysis and interpretation.
Maintains substantial current knowledge in relevant state-of-the art principles and technologies in clinical microbiology, microbial physiology, biochemistry and data analysis methods. Exercises and contributes to intellectual property and the scientific literature.
Collaboratively performs testing on prototype instruments and executes subsequent formal validations.
Develops protocols and experimental procedures to address issues or evaluate potential designs. Writes reports, specification or documents related to these efforts.
Prepares procedures, write technical reports, publishes research papers, and makes recommendations based on their research findings
Identifies clinical microbiology needs, and innovates novel concepts, approaches, and solutions for addressing those needs
Engages in collaborative efforts with academic, hospital and other external organizations. May have responsibility for managing third-party relationships.
May have personnel management responsibilities.
Required Education and Experience:

A minimum of a Bachelor’s degree in an appropriate field with at least 5 years of relevant Microbiology experience.
MS or PhD preferred.
The successful candidate will have a demonstrated aptitude for solving problems involving biological and instrumented platforms.
Experience with data storage, processing and analysis is desirable.


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Scientist I Antibody Development

Date Posted:
3/17/2017

MSD

MD

The Antibody Development Scientist will provide guidance for development and characterization of recombinant antibodies. The candidate will be responsible for, but not limited to: (1) analyzing and optimizing of antibody sequences; (2) phage display or other antibody display technologies; (3) screening antibodies for specificity; (4) functional testing of antibodies (5) development of purification and antibody handling procedures. The candidate will advise senior management on new techniques, methods, and strategies for making and improving recombinant antibodies. Independently designing and executing experiments, analyzing resulting data and presenting findings in a clear and concise manner will be among the principle responsibilities a Scientist is accountable for. Documentation duties will include keeping detailed records of experiments and product development, writing procedures, and preparing experimental summaries. This position may supervise the work of others directly and/or across interdisciplinary teams. The candidate must be able to manage several projects and coordinate between multiple groups. He/she must have excellent communication and interpersonal skills.

DUTIES AND RESPONSIBILITIES:

Bench Research/Hands-on laboratory work

Experiment planning and associated product documentation
Conduct experiments, analyze and critically review resulting data
Procure reagents and equipment
Understand and follow laboratory safety precautions and ensure compliance with company safety policies
May work with Biosafety Level 2 (BSL-2) materials such as viruses, bacteria and/or human clinical matrices (e.g. serum and plasma)
Participate in general lab maintenance
Computer/desk work

Prepare product documentation including summary reports
Troubleshoot and optimize experiments; communicate issues and solutions to managers
Write SOPs and assemble batch records
Present results to colleagues
Research new methods and train laboratory personnel
Cross-functional Coordination

Coordinate with other groups within the company
May manage and coordinate the activities of Research Associates
This may include a team of direct reports
Specific duties may vary depending upon departmental requirements

Requirements
EXPERIENCE AND QUALIFICATIONS:

 

Ph.D. in Life Sciences or related field
Minimum of two years laboratory experience with proven hands-on technical abilities
M.S. may be considered with additional years of experience
It is preferable to have a candidate with experience in recombinant antibody development.
The ideal candidate should have at least 3 years of experience in developing and optimization of recombinant antibodies with direct experience in phage display or related antibody display technologies
Excellent academic record and strong scientific fundamentals
Independent research experience
Industry experience is a plus
A demonstrated level of consistency in performance and aptitude for managing additional responsibility and accountability are required for next level consideration

KNOWLEDGE, SKILLS AND ABILITIES:

 

Strong scientific fundamentals and analytical background
Logical problem solving and demonstrated ability to organize and move project tasks forward in an orderly and structured fashion
Demonstrate ability to independently design and execute assay and reagent troubleshooting, optimization and validation experiments
Excellent oral, written communication and interpersonal skills are required
Effectively communicate issues/problems and results that impact timelines, accuracy and reliability of laboratory data
Effectively communicate performance goals and expectations
Proficiency in MS Office Suite
Experience with standard data analysis tools (Excel, GraphPad Prism) and the quantitative background to advance this knowledge on the job is expected
A wide degree of creativity and latitude is expected including the ability to multi-task in an environment with changing priorities


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Postdoc HIV

Date Posted:
3/17/2017

Duke

NC

The Duke Human Vaccine Institute (DHVI), an international leader in the fight against major infectious diseases, is currently recruiting for Postdoctoral Associates to join our research team. The Duke Human Vaccine Institute is an interdisciplinary, interdepartmental institute dedicated to the study of basic and translational science required to understand host-pathogen interactions that can be translated to vaccines against human diseases. Directed by Dr. Barton Haynes, we are a team of highly interactive investigators that have expertise in immunology, molecular biology, virology, microbiology, computational biology, and vaccine science. We are seeking highly motivated recent PhD graduates (Immunology, Molecular Biology, Biochemistry, Biomedical Engineering, Computational Biology, Virology or related scientific field) to play an integral role in the following projects related to HIV/AIDS Vaccines and Cure research and identification of correlates of protection for other diseases such as malaria:

• Identification of protective B cell responses through evaluation of HIV immunogens in animal models and in human vaccines. (Dr. Barton Haynes)
• Interrogate the biophysical properties of antibody-antigen binding interactions to provide insights into the mechanisms of protective immunity for HIV-1, malaria and other pathogens. (Dr. Georgia Tomaras)
• Assessment of immune-based strategies for prevention of maternal and pediatrics HIV/AIDS. (Dr. Sallie Permar)
• Investigate the development of HIV antibodies by analyzing immune repertoire sequencing and computationally design immunogens for human vaccines (Dr. Kevin Wiehe)

The DHVI has a dynamic mentoring program, directed by Dr. Georgia Tomaras, and our postdoctoral associates work in concert with Duke faculty and staff in an invigorating research training environment. One of our chief scientific missions is to support and train early stage investigators to be the next generation of scientific leaders equipped to identify and implement solutions for improving human health worldwide.

DHVI functions as not-for-profit vaccine development biotechnology enterprise, embedded within a top university. As a trainee within our mentoring program, you will interact with highly innovative and collaborative investigators and have the opportunity to master state of the art technologies. We are committed to providing an outstanding training environment and research experiences that will enhance your career. The education, expertise, initiative and dedication of the postdoctoral associates engaged in these projects will be important to the success of the studies. This is an opportunity to become part of a winning team that is working to discover novel ways to prevent infectious diseases.
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Bioinformatic Scientist

Date Posted:
3/17/2017

Gene Centric

NC

GeneCentric is seeking a Bioinformatics Scientist to join a growing team in Durham, North Carolina. GeneCentric is a biotech company developing novel cancer taxonomy diagnostics to facilitate more efficient drug development and improved patient care. The successful applicant will contribute to efforts developing novel computational tools for classification of tumors. He/She will support research activities and collaborative studies involving the use of complex algorithms for analysis of RNA and DNA sequence data and modeling to identify new associations. Ability to process raw sequencing data for variant identification and gene expression analysis, as well as skills for integrating diverse -omics data are required. Candidates with experience in the pharmaceutical industry are encouraged to apply.
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Job Requirements
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Qualifications and Skills Required
• Proficiency in the use of bioinformatics tools (e.g. GATK, BLAST, BWA, SAMtools, Freebayes, etc. ), file formats (e.g. FASTQ, BED, BAM, VCR), and publicly available databases (e.g. GEO, ClinVar, GenBank, Ensemble, COSMIC, OMIM, Annovar, dbSNP, etc.).
• Proficiency in transcriptome profiling, differential expression, and functional profiling (e.g., STARaligner, TopHat, CuffLinks, Bowtie, Kallisto, Blast2Go)
• Strong Unix skills and programming ability in at least one of the following: R, Python, Java, or Perl.
• Experience applying statistical models, Bayesian Networks, and performing hypothesis testing.
• Strong oral and written communication skills for presenting analysis results internally and externally required.

Education and Experience
• PhD degree in Bioinformatics, Genomics, Statistics, Biostatistics, Computational Biology, or equivalent, with a minimum of 3 years of relevant experience.
• Masters level candidates with at least 5 years of relevant experience may be considered if they have the required knowledge and experience.


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Lead Scientist Signal Transduction

Date Posted:
3/17/2017

KXT Bio

NC

Lead scientist sought to develop product portfolio focused on signal transduction cascades controlled by GTPases. KXTbio is a startup company with intellectual property used to monitor the activation of GTPases and their effectors. The successful candidate will be responsible for protein purification, assay optimization, and the development of new biochemical reagents. Ph.D. or equivalent required. Must have extensive laboratory experience in biochemistry or related discipline and excellent communication skills.

Excellent scientific and entrepreneurial opportunity for highly motivated individual.

Scientific independence and creativity also required. 50Kto 75K


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Scientist In Vivo Pharmacology

Date Posted:
3/17/2017

Sage Therapeutics

MA

AGE Therapeutics is searching for a creative, resourceful, integrative thinker for an important role that is responsible for managing in vivo pharmacology studies across Discovery and Development programs, applying knowledge of advanced principles, theories, and concepts in areas of expertise.

Roles and Responsibilities
Plans and ensures execution of laboratory research, with general guidance; investigates, selects, and/or develops new methods and technologies for project advancement; monitors work-flows to enable execution of studies.
Design and interpret in vivo pharmacology studies to evaluate the activities of small molecule drug candidates, investigate their mechanisms of action, and explore novel therapeutic hypotheses
Manage in vivo pharmacology research in a matrixed environment, as well as external academic collaborations and an extensive network of CROs
Prepare, review and deliver scientific presentations for internal/external use.
Maintains knowledge of state-of-the-art principles and theories, and applies this knowledge to the design, execution, and interpretation of experiments.
Contributes to the preparation of lucid scientific reports for projects teams; writes and reviews SOPs, contributes to scientific literature, conferences and publications.
Uses scientific knowledge and Sage’s policies and procedures to solve problems.
Plans own activities and weekly schedule with guidance in accordance with objectives and priorities.
Experience, Education and Specialized Knowledge and Skills

Must thrive working in a fast-paced, innovative environment while remaining flexible, proactive, resourceful and efficient. Excellent interpersonal skills, ability to develop important relationships with key stakeholders, good conflict management and negotiation skills, ability to analyze complex issues to develop relevant and realistic plans, programs and recommendations. Demonstrated ability to translate strategy into action; excellent analytical skills and an ability to communicate complex issues in a simple way and to orchestrate plans to resolve issues and mitigate risks.
Ph.D. in Neuroscience, Pharmacology, Biomedical Science or a scientific discipline with 0 - 3 years of relevant experience; or MS/MA with at least 5+ years of relevant experience; or BS/BA with at least 8+ years of relevant experience. A proven track record in progressing drug targets from validation to early clinical development is an asset.
Experience with conducting in vivo models of disease and evaluating pharmacological interventions.
Ability and willingness to work effectively in a highly collaborative, matrixed research environment.
Possess a strong attention to detail and have exceptional interpersonal, organizational and communication skills
Embrace our core values: Put People First, Do Big, Be Accountable, Grow through Learning and Change, and Work Fun
Excitement about the vision and mission of Sage


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Postdoc Molecular/Cell Biology

Date Posted:
3/17/2017

Syros

MA

Syros Pharmaceuticals is pioneering the understanding of the non-coding region of the genome to advance a new wave of medicines that control expression of disease-driving genes. Syros has built a proprietary platform to systematically and efficiently analyze this unexploited region of DNA in human disease tissue to identify and drug novel targets linked to genomically defined patient populations. Because gene expression is fundamental to the function of all cells, the Company’s gene control platform has broad potential to achieve profound and durable benefit across a range of diseases. Syros is focused on cancer and immune-mediated diseases and is advancing a growing pipeline, including its lead drug candidates SY-1425, a selective RARα agonist for genomically defined subsets of patients identified by its platform, for a range of cancers including acute myeloid leukemia and myelodysplastic syndrome, and SY-1365, a selective CDK7 inhibitor for a range of blood cancers and solid tumors. Led by a team with deep experience in drug discovery, development and commercialization, Syros is located in Cambridge, Mass.

Syros Pharmaceuticals is seeking an experienced Cell and Molecular Biologist to join a team of highly motivated scientists that are discovering new oncology drug targets and developing small molecule modulators of gene regulation.

The candidate must have a recent PhD in cell and molecular biology or related field. Experience in transcriptional regulation, epigenomics, drug discovery, oncology and familiarity with genome editing and genome-wide techniques are desired.

Responsibilities:

  • ?  Integrated data analysis and interpretation of genomic, epigenomic and transcriptional datasets

  • ?  Performance of next-generation epigenomic assays including ChIP-seq and RNA-seq

  • ?  Development of cell-based gene reporter models using CRISPR-mediated gene editing

  • ?  Biochemical isolation of transcriptional regulatory complexes

  • ?  High throughput chemical and CRISPR-based screening Requirements:

  • ?  Recent PhD degree in Cell Biology, Molecular Biology or related field with 2-5 years experience in transcriptional biology and epigenomics

  • ?  Familiarity with design and application of gene editing tools including CRISPR

  • ?  Standard molecular biology skills: DNA and RNA isolation, PCR, molecular cloning, transfection, protein isolation,

    cloning and immunodetection

  • ?  Experience with protein isolation and purification

  • ?  Strong attention to detail and the ability to handle multiple tasks

  • ?  Desire and ability to work in a fast paced, cross-functional, flexible and team-oriented environment

  • ?  Independent thinking, experimentation and analysis

  • ?  Strong interpersonal and written communications skills

    Candidates who are keen experimentalists, independent thinkers and enthusiastic team players that have a passion for drug discovery are encouraged to apply. Preference given to candidates with previous expertise in creating cell-based models through gene engineering, transcription factor biology and chromatin biology.


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Scientist/Senior Scientist Immunology

Date Posted:
3/17/2017

Syros

MA

Syros Pharmaceuticals is pioneering the understanding of the non-coding region of the genome to advance a new wave of medicines that control expression of disease-driving genes. Syros has built a proprietary platform to systematically and efficiently analyze this unexploited region of DNA in human disease tissue to identify and drug novel targets linked to genomically defined patient populations. Because gene expression is fundamental to the function of all cells, the Company’s gene control platform has broad potential to achieve profound and durable benefit across a range of diseases. Syros is focused on cancer and immune-mediated diseases and is advancing a growing pipeline, including its lead drug candidates SY-1425, a selective RARα agonist for genomically defined subsets of patients identified by its platform, for a range of cancers including acute myeloid leukemia and myelodysplastic syndrome, and SY-1365, a selective CDK7 inhibitor for a range of blood cancers and solid tumors. Led by a team with deep experience in drug discovery, development and commercialization, Syros is located

in Cambridge, Massachusetts.

Syros Pharmaceuticals is seeking a dynamic Cell Biologist/ Immunologist to join a team of highly motivated scientists that are using recent fundamental insights into transcriptional regulation to discover and develop novel medicines targeting gene control in cancer and autoimmunity.

The Scientist will participate with project teams in shaping the Immunology and Immuno-Oncology research strategy. The motivated individual will be responsible for cell assay development for new target identification and validation for Syros’ discovery and development teams. The successful candidate will have broad subject expertise including Immunology, Cell and Molecular Biology, and Cancer Biology. Expertise in immunological assays including multi-parameter FACS analysis of primary cells, ELISA, and cell differentiation/proliferation and tumor co-culture assays is required. In addition, the candidate should have expertise in design, execution, and interpretation of in vitro and in-vivo studies for target validation of potential drug targets in the autoimmune and immuno-oncology area. Previous work in immune-oncology biology is a plus.

Responsibilities:
-Provide scientific capabilities in the areas of immuno/oncology and autoimmunity to both preclinical discovery project and development project teams.

-Deliver critical project data internally and through a network of external study providers and collaborate with leading KOLs.
-Participate in biological selection and in vitro validation of novel drug targets
-Participate in discussions with project team biologists to define the appropriate dose & schedule for novel drug candidates in the chosen in vivo model; Practical understanding of PK/PD concepts in order to design in vivo studies for proof of concept is recommended.

- Work with project teams, external collaborators, and CROs, on existing programs and new drug target programs to design, operationalize, and interpret studies to validate potential drug targets in the area of autoimmunity and immuno-oncology

-Facilitate project transitions from Discovery to Preclinical Development in close collaboration with discovery, preclinical, and clinical/translational scientists.

620 Memorial Drive | Suite 300 | Cambridge, MA | 02139 | tel. 617.744.1340 | fax 617.744.1377

- Must be flexible and able to contribute to an evolving portfolio of projects spanning early discovery through preclinical stage.
-Clear communication and presentation skills are a requirement

Requirements:
Ph.D. in Immunology or Cell/Molecular Biology or equivalent area with at least 3 years of postdoctoral

training with a proven track record of publications in peer reviewed journals. Prior pharmaceutical industry experience is a plus.


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Senior Research Associate/Scientist Translational Biology

Date Posted:
3/17/2017

Syros

MA

Senior Research Associate/Scientist, Translational Biology

Syros Pharmaceuticals is pioneering the understanding of the non-coding region of the genome to advance a new wave of medicines that control expression of disease-driving genes. Syros has built a proprietary platform to systematically and efficiently analyze this unexploited region of DNA in human disease tissue to identify and drug novel targets linked to genomically defined patient populations. Because gene expression is fundamental to the function of all cells, the Company’s gene control platform has broad potential to achieve profound and durable benefit across a range of diseases. Syros is focused on cancer and immune-mediated diseases and is advancing a growing pipeline, including its lead drug candidates SY-1425, a selective RARα agonist for genomically defined subsets of patients identified by its platform, for a range of cancers including acute myeloid leukemia and myelodysplastic syndrome, and SY-1365, a selective CDK7 inhibitor for a range of blood cancers and solid tumors. Led by a team with deep experience in drug discovery, development and commercialization, Syros is located in Cambridge, Massachusetts.

Syros Pharmaceuticals is seeking an experienced Cell and Molecular Biologist to join a team of highly motivated scientists and clinical researchers in the translational medicine group, who are using recent fundamental insights into transcriptional regulation to discover and validate new oncology targets. This particular role will focus on gaining a deeper understanding of the effect of small molecules on model systems, including mouse studies, and helping to translate these insights in clinically actionable concepts in drugs that are moving forward into clinical development. The successful candidate will be expected to have a high degree of autonomy in designing and analyzing experiments with contributions toward presentations and publications in support of the project. These contributions will help guide the development of programs as they advance to the clinic and in the write up of scientific publications.

The candidate must have a PhD or 3-6 years of experience in academia or industry in maintaining human cell lines in tissue culture, familiar with use of small molecules in cancer biology including mechanism of action studies and must be proficient in standard molecular biology practices including RNA prep and qPCR. Experience with in vivo models of cancer and IHC based follow up is a plus. An interest in design and execution of experiment with a translational focus to support novel strategies in drug development is highly desirable.

Responsibilities:

  • ?  Performance of protein enrichment (IP) and ChIP-Seq experiments

  • ?  Determination of cell line sensitivities to gene regulation modulators

  • ?  Design and oversight of in vivo studies

  • ?  Tissue culture for cancer cell lines and primary samples

  • ?  Execution of overexpression and knockdown (shRNA/siRNA) experiments

  • ?  Detailed mechanism of action investigations

  • ?  Determination of target engagement from in vitro and in vivo samples

  • ?  qPCR and Western blot based expression quantitation of target genes

  • ?  Integrated data analysis and interpretation

    Requirements:

  • ?  BS or MS degree with 3-6 years of experience or PhD in Cell Biology or related field

  • ?  Basic molecular biology skills: DNA and RNA isolation, PCR, molecular cloning, protein processing and

    immunoblotting

  • ?  Familiarity with protein overexpression and knockdown strategies (RNAi and shRNA) in mammalian cells


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Senior Scientist, Molecular/Cell Biology

Date Posted:
3/17/2017

Syros

MA

Senior Scientist, Molecular/Cell Biology

Syros Pharmaceuticals is pioneering the understanding of the non-coding region of the genome to advance a new wave of medicines that control expression of disease-driving genes. Syros has built a proprietary platform to systematically and efficiently analyze this unexploited region of DNA in human disease tissue to identify and drug novel targets linked to genomically defined patient populations. Because gene expression is fundamental to the function of all cells, the Company’s gene control platform has broad potential to achieve profound and durable benefit across a range of diseases. Syros is focused on cancer and immune-mediated diseases and is advancing a growing pipeline, including its lead drug candidates SY-1425, a selective RARα agonist for genomically defined subsets of patients identified by its platform, for a range of cancers including acute myeloid leukemia and myelodysplastic syndrome, and SY-1365, a selective CDK7 inhibitor for a range of blood cancers and solid tumors. Led by a team with deep experience in drug discovery, development and commercialization, Syros is located in Cambridge, Massachusetts.

Syros Pharmaceuticals is seeking an experienced molecular/cell biologist to join a team of highly motivated scientists that are using recent fundamental insights into transcriptional regulation to discover and develop novel medicines targeting gene control.
The candidate must have a Ph.D. degree in Cell Biology, Biochemistry or a related discipline and have 4-6 years of productive post Ph.D. research experience proven by a strong record of achievement. Experience in the biotech/pharma industry preferred. This is a rare opportunity to join an exceptional start-up pushing the boundaries of drug discovery.

Responsibilities:

  • ?  Serve as biology project lead for small molecule drug discovery projects

  • ?  Investigate molecular mechanism of action of small molecules impacting transcriptional control using

    sophisticated transcriptomic and epigenomic analysis

  • ?  Integrate biological (e.g., CRISPR,shRNA) with compound mediated perturbation of cells to develop PD

    markers

  • ?  Use insights from mechanistic work to develop predictive markers for patient selection

  • ?  Execute integrated data analysis and interpretation in collaboration with computational biology group

  • ?  Prepare written documents to support regulatory submissions

  • ?  Initiate and develop external collaborations with external

  • ?  Present data in abstracts, posters, talks and peer-reviewed publications

    Requirements:

  • ?  Ph.D. in Cell Biology, Biochemistry or related field with 4-6 years of experience in testing and elucidating MOA

    of small molecules, preferably in industry

  • ?  Strong record of achievement (peer reviewed publications or regulatory documents)

  • ?  Familiarity with genetic and gene modulation techniques to analyze gene function

  • ?  Experience in genome wide transcriptional and epigenomic profiling

  • ?  Ability to extract insights from data rich experiments

  • ?  Familiarity in the design and execution of in vivo experiments

  • ?  Experience in writing and editing of reports suitable for IND submission

  • ?  Attention to detail and the ability to simultaneously handle multiple projects

  • ?  Desire and ability to work in a cross-functional and flexible team-oriented environment

  • ?  Strong interpersonal and strong verbal and written communications skills

    Candidates who are keen experimentalists, enthusiastic, creative and have a passion for drug discovery are encouraged to apply. Knowledge of cancer biology and transcriptional regulation is a plus.


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Senior Scientist Hematopoietic Stem Cells

Date Posted:
3/17/2017

Intellia

MA

COMPANY:

Intellia is developing therapeutic products to help people with genetic diseases. We apply CRISPR/Cas9 genome editing and gene therapy technologies to edit and restore genes to their normal, healthy sequence. We are a dedicated team driven to change patients’ lives. As we build our team, we’re excited to work with people who share our commitment and energy to making a difference.

SUMMARY:

We are looking for a Senior Scientist to join a growing team to execute on Intellia’s ex vivo programs, including engineering hematopoietic stem and progenitor cells with CRISPR/Cas9 to develop therapeutics for genetic disesase. The Senior Scientist will be involved in design and execution of an experimental plan to develop therapeutics for genetic diseases using hematopoietic stem cells. This unique role will place the successful candidate in a dynamic position as a key member of the team, interfacing regularly with company senior management and being involved in decision-making and in interactions with external stakeholders.

Develop disease specific therapeutic strategies including target identification, delivery systems and functional assays
Develop and optimize protocols for engineering cells using viral and non-viral vectors, including validation protocols
Design experiments, interpret data, and problem solve with a high level of independence and creativity to advance company’s cell therapy platform
Communicate research and development findings with internal and external partners.
Mentor and guide other scientists in the group as needed
REQUIRED SKILLS:

Strong understanding of and experience with human hematopoietic stem cell biology
Mouse xenotransplantation and/or mouse models of human disease
Demonstrated ability to identify, design, and drive innovative programs and demonstrated evidence of scientific “problem solving”.
Excellent time management and the ability to multi-task is essential
PREFERRED SKILLS and EXPERIENCE:

Experience working with viral and/or non-viral delivery systems.
Experience with cell cycle and/or DNA damage analysis.
Strong knowledge of gene editing is highly desired.
A detailed knowledge of stem cell, cellular and/or tumor immunology principles, technologies, and experimental techniques (cell culture, in vitro cellular assays, flow cytometry, etc…)
Demonstrated track record of successfully developing and employing in vitro/in vivo models
Demonstrated ability to lead and complete projects
Previous supervisory experience
QUALIFICATIONS:

Ph.D. with 2-6+ years of relevant experience in the field of stem cell biology.
Strong publication record related to cellular and molecular biology in the field of hematopoiesis
POSITION: Full-Time, Exempt

LOCATION: Cambridge, MA

EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.


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Computational Biologist

Date Posted:
3/17/2017

Intellia

MA

COMPANY:

The development of CRISPR/Cas9 gene editing technology opens a new frontier in biomedical research and clinical intervention. Adapted from a natural cellular process, CRISPR/Cas9 permits the editing of any gene in any organism with unprecedented simplicity and flexibility. Intellia Therapeutics was founded in 2014 by Caribou Biosciences and Atlas Venture, along with a consortium of leading scientists who have helped define the space. Intellia Therapeutics holds exclusive access to a broad intellectual property portfolio covering the application of CRISPR/Cas9 technology for human therapeutic use. As we build our team, we’re looking for people who share our commitment and energy to make a difference.

SUMMARY:

Intellia Therapeutics is seeking a computational biologist/bioinformatian to support the development of CRISPR/Cas9 based therapeutics. This position is an opportunity to contribute to diverse aspects Intellia's bioinformatics platform from the building pipelines for processing NGS data to analyzing downstream data.

RESPONSIBILITIES:

Develop and support NGS pipelines using commonly utilized tools (BWA, bowtie, samtools, etc)
Apply rigorous statistical methods for testing hypotheses on processed data
Implement and optimize databases and data storage methods
Work with scientists to develop computational methods and tools to support new assays and implement data analyses
Create scientifically rigorous visualizations, communications, and presentations of results
QUALIFICATIONS:

BS/MS with 2+ years experience or recent PhD in computational biology/bioinformatics or equivalent field
Demonstrated ability to write elegant and clean code in R, Python, Perl, or C++
Experience processing and analyzing biological data, especially sequencing data
Familiarity with Linux and shell scripting/bash


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Scientist I Biochemistry and Assay Development

Date Posted:
3/17/2017

Myokardia

CA

SUMMARY: Responsible for developing new assays and tools that enable mechanistic understanding of sarcomere modulators, as well as providing experimental support and direction for existing development strategies. Highly-motivated expert in sarcomere biology, biochemistry, and/or biophysics who can effectively communicate to diverse teams. Must possess strong desire to “lead from the bench” with creative, problem-solving mindset and keen ability to guide junior scientists.

 

ESSENTIAL DUTIES AND RESPONSIBILITIES:

Develop and validate both novel and established biochemical and biophysical assays to measure how potential therapeutic agents affect sarcomere function
Work with project teams to help guide lead optimization and build an effective bridge between in vitro biochemical modulation and in vivo effects on cardiac function
Collaborate with Cell Biology and Translational Science teams to create and design assays to link biochemical and biophysical assays to in vivo studies
Plan and perform critical-path experiments in a manner consistent with the timelines and objectives of therapeutic program teams
Contribute to pre-clinical and clinical reports/documents
Collaborate proactively and communicate effectively with multidisciplinary teams
Participate and present data at internal and external meetings

EDUCATION/EXPERIENCE/SKILLS:

Education:

Requires a PhD with 3+ years experience OR a Masters with 10+ years experience in biochemistry, biophysics, cell biology or related discipline sarcomere (deep knowledge of and experience working with the sarcomere of highest importance)

Requirements:

Minimum of 4+ years related experience; may include post-doctoral experience
Expert knowledge of enzyme kinetics, biophysical methods, and sarcomere biology/biochemistry/biophysics
Experience with collaborative participation in diverse team environments
Excellent verbal and written communication skills
Ability to delve into literature to define protocols, gain mechanistic insights, form testable hypotheses, and challenge existing assumptions
Reputation as emerging leader in sarcomere biology field with sustained performance with peer-reviewed publications and accomplishments to support this


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Scientist Phage Display UK

Date Posted:
3/17/2017

Agenus

INT

Overview:

We have an exciting opportunity for a Scientist with a background in Phage / Yeast display to join our team at our new site in Cambridge.
This is a state of the art facility located in the centre of Cambridge specialised in the development of biopharmaceuticals of Immuno Oncology targets.
You will be part of a global team, with opportunities to grow with the company.
Responsibilities:

Expected to independently carry out phage display / yeast display selections, from naïve selections and affinity maturation campaigns
Willingness to take the lead on programme teams as the “antibody expert”, to advise on antibody engineering aspects and to effectively select leads that will lead to genuine drug candidates
Aid in the building of new libraries, both practically and theoretically. Able to build affinity maturation libraries for key candidates
Expected to express and purify lead antibodies to small scale, and to conduct initial binding and biophysical screens. Able to work closely as part of team to make a decision on the best antibody candidates to take forward
Expected to give regular presentations, both internally and company wide
Manage all antibody data with the project and collate results
Laboratory based – is willing to take the lead within the laboratory and serve as subject matter expert
Is willing to supervise and mentor 1-2 scientific staff within the phage display group
Maintain a current and accurate laboratory record (lab notebook) of all activities
Qualifications:

MSc with >7 industrial experience or PhD in a biological science/biochemistry discipline. Experience in an industrial setting is desirable
Experience:
Experience in phage display, particularly with ScFv and/or Fab formats. Able to work independently in panning and selections of antibody formats for a variety of targets
Experience in yeast display would be an advantage
Able to identify and characterise lead clones from phage display campaigns using a variety of assays (RBA, ELISA, Biacore etc) in order to progress drug discovery programmes.
Must be project aligned and work effectively as part of a multidisciplinary team
Excellent molecular biology techniques: cloning, PCR, sequencing analysis.
Protein expression and purification on small scale required. Some experience in HTS expression and screening of antibodies would be advantageous
Experience with BIAcore and/or Luminex as tools to screen would be desirable
Experience with affinity maturation of antibody fragments using a variety of different techniques
Strong analytical and critical thinking skills with the ability to interpret complex data
Excellent written and verbal communication skills.
Ability to present data, both locally and company wide


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Scientist Cell Line Development UK

Date Posted:
3/17/2017

agenus

INT

Overview:

We have an exciting opportunity for a Scientist to join our new Cell Line Development Team in Cambridge.
This is a state of the art facility located in the centre of Cambridge specialised in the development of biopharmaceuticals of Immuno Oncology targets.
You will be part of a global team, with opportunities to grow with the company.



Responsibilities:

Conducting stable cell line development projects, including design, partial execution in timely manner, reporting to Molecule Project Teams.
Liaise and coordinate CLD projects with Process Development and Process Analytical groups.
Serve as Subject Matter Expert on Project Teams for early and late-stage projects.
Author and review documents in support of regulatory filings from IND/CTA to BLA.
Develop, evaluate and implement new technologies, methods and third party technology for process improvement.
Write working instructions or SOPs, technical reports and mentor junior staff.
Aid in the preparation and presentation of publications, presentations, regulatory documents and/or primary inventor of patents.
Liaise closely with collaborators and sites globally, maintain clear and efficient communication.
Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials, controlled drug, GxP compliance, where applicable.
Qualifications:

MSc with industrial experience (2-5 years) in relevant field or PhD in a biological science/biochemistry discipline.
Experience:
Experience in mammalian cell culture techniques (adherent and suspension cells, CHO, HEK) in various scales, from multi-wells to small scale bioreactors.
Experience in efficient transfections and selection of highly expressing stable cell lines, single cell cloning, evaluation of cell lines for productivity and product quality, cell banking. Experience with using FACS or ClonePix in developing monoclonal antibody expressing cell lines is a bonus.
Skills in molecular biology: construction of expression vectors, evaluation of expression and stability enhancing elements.
Experience with automation in cell line development and product analysis is highly desirable.
Experience with evaluation of cell line stability, both at the cell culture and genetic level.
Experience in an industrial setting is preferable.

Profile:
Ability to work autonomously and in a team.
Highly autonomous and productive in performing laboratory experiments or method development.
Outstanding organizational and multi-tasking skills; able to manage several projects/cell lines simultaneously.
Ability to effectively work on multiple project teams and changing project priorities.
Excellent writing and communication skills, good attention to details.
Supervise and mentor scientific staff as well as communicate effectively to senior management as appropriate.


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Ophthalmology Research Lead

Date Posted:
3/17/2017

Spark

PA

The Ophtalmology Lead will manage the Ophthalmology functional group within the Discovery Research group under Translational Research. He/she will be responsible for:
Providing leadership within a group of 2 to 3 scientists/research associates, to develop pre-clinical programs from early discovery to the clinic.
Initiate and oversee joint programs with academic collaborators.
Establishing project timelines and ensuring work is completed according to schedule.
Training and developing staff at varying levels of experience.
The Ophtalmology Lead position requires extensive translational experience with ocular gene therapies, including:
In-depth familiarity with target validation and lead identification/optimization, using a combination of molecular, cellular and in vitro/in vivo techniques for ophthalmic gene therapy.
Familiar with intraocular delivery techniques and have substantial experience with ophthalmic studies in laboratory animals.
In-depth knowledge of inherited retinal disorders is required. Some familiarity with AAV, as well as some knowledge of clinical trial design and regulatory strategy, is preferred.
RESPONSIBILITIES:
40% of the time
Hands-on execution of experiments on the bench
30% of the time
Identify and validate new indication targets. Design and trouble-shoot experiments based on personal experience and literature review. Prepare and deliver scientific presentations at internal and external meetings
10% of the time
Prioritize projects, plan workload, manage resource and personnel scheduling
10% of the time
Preparing sample analysis reports and write parts of regulatory submissions to FDA
10% of the time
Lead a team of scientists. Mentor and develop staff.
Ensure departmental goals and objectives are met and aligned to the broader organizational goals and objectives.
QUALIFICATIONS:
Extensive hands-on experience in ocular gene therapy, such as intravitreal and subretinal injections, pupillometry, etc.
Strong organizational skills.
Excellent writing and verbal communication skills.
Previous management experience preferred, but not required.
Strong publication record is a plus.
Experience with AAV vectors is a plus.
REQUIREMENTS:
Ph.D. in relevant scientific discipline (e.g. cell and molecular biology, biochemistry, etc.)
Minimum 5-8 years of hands-on experience in the field of ophthalmic gene therapy
Previous management or supervisory experience strongly preferred
WHO WE ARE:
Transforming Patient’s Lives. Spark Therapeutics is a pioneering gene therapy leader transforming the lives of patients suffering from debilitating genetic diseases by developing one-time, life-altering treatments. We are embarking on our goal to deliver the first approved gene therapy product in the US for genetic blinding conditions and have a product pipeline addressing other unmet rare genetic diseases. We have an entrepreneurial culture and are looking for talented and passionate professionals who are committed and motivated to making a difference in the lives of our patients. If you share our passion for excellence and are looking for a dynamic work environment that fosters creativity, scientific innovation and team collaboration, you may be a great fit for our team.

 


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Translational Research Lead Liver

Date Posted:
3/17/2017

Spark

PA

The Liver Lead will manage the Liver functional group within the Discovery Research group under Translational Research. He/she will be responsible for:

• Providing leadership within in a group of scientists/research associates, to develop pre-clinical programs from early discovery to the clinic.
• Initiate and oversee joint programs with academic collaborators.
• Establishing project timelines and ensuring work is completed according to schedule.
• Training and developing staff at varying levels of experience.

The Liver Discovery Research Lead position requires extensive translational experience with gene therapies targeting the liver, including:

• In-depth familiarity with target validation and lead identification/optimization, using a combination of molecular, cellular and in vitro/in vivo techniques for hepatic gene therapy programs.
• Familiar with delivery techniques targeting the liver and have substantial experience with studies in laboratory animals.
• Some familiarity with AAV, as well as some knowledge of clinical trial design and regulatory strategy, is preferred.

RESPONSIBILITIES:
Hands-on execution of experiments on the bench
Identify and validate new indication targets. Design and trouble-shoot experiments based on personal experience and literature review. Prepare and deliver scientific presentations at internal and external meetings
Prioritize projects, plan workload, manage resource and personnel scheduling
Preparing sample analysis reports and write parts of regulatory submissions to FDA
Lead a team of scientists. Mentor and develop staff.
Ensure departmental goals and objectives are met and aligned to the broader organizational goals and objectives.
EDUCATION and EXPERIENCE REQUIREMENTS:
Ph.D. in relevant scientific discipline (e.g. cell and molecular biology, biochemistry, etc.)
Minimum 5-8 years of hands-on experience in the field of gene therapy.
Previous management or supervisory experience strongly preferred.
KEY SKILLS, ABILITIES and COMPETENCIES:
Extensive hands-on experience in hepatic gene therapy techniques, such as intravenous injection, hepatocyte isolation, etc.
Strong organizational skills.
Excellent writing and verbal communication skills.
Previous management experience preferred, but not required.
Strong publication record is a plus.
Experience with AAV vectors is a plus.
COMPLEXITY and PROBLEM SOLVING:
Demonstrate independent problem solving skills of technical issues; develop solutions to a variety of moderate to complex problems. Discuss with supervisor and refer to policies/practices for guidance.
Must be comfortable in the fast-paced, biotech start-up environment and interact with multi-disciplinary research teams at Spark.
Exercise judgment within defined procedures and practices to determine appropriate action.
INTERNAL and EXTERNAL CONTACTS:
Quality Assurance, Clinical Operations, Pharm/Tox, Discovery, Assay Development, R&D Operations, Technical Operations, Regulatory Affairs, Executive Team.

WHO WE ARE:
Transforming Patient’s Lives. Spark Therapeutics is a pioneering gene therapy leader transforming the lives of patients suffering from debilitating genetic diseases by developing one-time, life-altering treatments. We are embarking on our goal to deliver the first approved gene therapy product in the US for genetic blinding conditions and have a product pipeline addressing other unmet rare genetic diseases. We have an entrepreneurial culture and are looking for talented and passionate professionals who are committed and motivated to making a difference in the lives of our patients. If you share our passion for excellence and are looking for a dynamic work environment that fosters creativity, scientific innovation and team collaboration, you may be a great fit for our team.

 


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Translational Research Lab Manager

Date Posted:
3/17/2017

Spark

PA

Manage the day to day technical operation of the translational lab, inclusive of: assay development, pharmacology & toxicology, and discovery research.
Champion all safety aspects in the Translational Laboratories.
Implement and manage an inventory system for biological reagents (plasmids, cells, vectors) and co-ordinate reception and shipment of reagents.
Train and assist technical staff in the performance of laboratory experiments ensuring work is completed according to project time lines.
Responsible for short and long term planning for all aspects of lab operations, maintaining focus on scientific goals of the pipe line programs.
Oversee and manage the day-to-day operations of our external vivarium vendor.
Ensuring adequate personnel, space, equipment, and facilities remain available.
Coordinate the work load in collaboration with other department leads.
RESPONSIBILITIES:
Independently design, determine techniques and perform experiments on the bench.
Mentor and develop staff. Train and assist technical staff in the performance of laboratory experiments. Responsible for all safety aspects and best practices, and employee training.
Ensure departmental goals and objectives are met and aligned to the broader organizational goals and objectives.
Prioritize and plan projects and workloads, manage resources and personnel scheduling.
Coordinate and align centralized lab management efforts across assay development, pharmacology, toxicology and discovery research.
Short and long term planning of lab operations
Oversee and manage the day-to-day operations of our external vivarium vendor
Implement and maintain Spark Translational inventory system
Supplier & Vendor Management and negotiations
Manage translational research samples and materials
EDUCATION and EXPERIENCE REQUIREMENTS:
Bachelor’s degree required; PhD in a relevant field preferred.
Minimum of 5-8 years of strategic and hands-on laboratory experience.
Previous management or supervisory experience strongly preferred.
Broad understanding of the technical and equipment needs in a lab as well as extensive hands-on experience with standard molecular and cell biology techniques such as DNA cloning, qPCR, ELISA, flow cytometry, cell culture, etc.
Experience with AAV vectors is a plus.
KEY SKILLS, ABILITIES and COMPETENCIES:
Strong organizational skills.
Excellent writing and verbal communication skills.
Demonstrated ability to effectively manage performance and talent.
COMPLEXITY and PROBLEM SOLVING:
Demonstrate independent problem solving skills of technical issues; develop solutions to a variety of moderate to complex problems; Discuss with supervisor and refer to policies/practices for guidance.
Must be comfortable in the fast-paced, biotech start-up environment and interact with multi-disciplinary research teams at Spark.
Exercise judgment within defined procedures and practices to determine appropriate action.
INTERNAL and EXTERNAL CONTACTS:
Quality Assurance, Clinical Operations, Pharm/Tox, Discovery, Assay Validation, R&D Operations, Technical Operations, Regulatory Affairs

 

WHO WE ARE:
Transforming Patient’s Lives. Spark Therapeutics is a pioneering gene therapy leader transforming the lives of patients suffering from debilitating genetic diseases by developing one-time, life-altering treatments. We are embarking on our goal to deliver the first approved gene therapy product in the US for genetic blinding conditions and have a product pipeline addressing other unmet rare genetic diseases. We have an entrepreneurial culture and are looking for talented and passionate professionals who are committed and motivated to making a difference in the lives of our patients. If you share our passion for excellence and are looking for a dynamic work environment that fosters creativity, scientific innovation and team collaboration, you may be a great fit for our team.

 


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Ocular Research Scientist

Date Posted:
3/17/2017

Spark

PA

The Ocular Research Scientist is a member of the Ocular functional group within Translational Research.

He/she will be responsible for:
Design, execution and data analysis for ocular-directed research programs.
Write study reports, manuscripts and present results at appropriate scientific meetings.
Initiate and oversee joint programs with external collaborators.
RESPONSIBILITIES:
Hands-on execution of in vitro and in vivo experiments on the bench.
Identify and validate new indication targets and evaluate gene expression cassettes to support both existing and new programs in the pipeline. This includes executing experiments on the bench, extensive literature review, championing product candidate development from proof of concept to IND submission, etc.
Prepare sample analysis reports and write parts of regulatory submissions to regulatory agencies.
QUALIFICATIONS:
Strong organizational skills.
Excellent writing and verbal communication skills.
REQUIREMENTS:
Ph.D. in relevant scientific discipline required (e.g. cell and molecular biology, biochemistry, etc.)
Minimum 2-3+ years of hands-on research experience with gene therapies targeting the eye.
In-depth familiarity with target lead identification/optimization using a combination of molecular, cellular and in vitro/in vivo techniques for ocular gene therapy programs.
Experience with delivery techniques targeting the eye (subretinal and intravitreal injections).
Experience with studies in laboratory animals.
Experience with AAV vectors is required.
Molecular biology proficiency is required.
Strong publication record is a plus.
Extensive hands-on experience in ocular gene therapy in animal models, such as intravitreal and subretinal injections, pupillometry, ERG, OCT, etc.
WHO WE ARE:
Transforming Patient’s Lives. Spark Therapeutics is a pioneering gene therapy leader transforming the lives of patients suffering from debilitating genetic diseases by developing one-time, life-altering treatments. We are embarking on our goal to deliver the first approved gene therapy product in the US for genetic blinding conditions and have a product pipeline addressing other unmet rare genetic diseases. We have an entrepreneurial culture and are looking for talented and passionate professionals who are committed and motivated to making a difference in the lives of our patients. If you share our passion for excellence and are looking for a dynamic work environment that fosters creativity, scientific innovation and team collaboration, you may be a great fit for our team.

 


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Biomedical Engineer - Device Design and Development

Date Posted:
3/17/2017

Semma

RI

Semma Therapeutics, a recently founded biotechnology company focused on developing a stem cell-based cell therapy for Type 1 diabetes, is seeking a scientist to join its growing team. The full-time role will focus on developing, evaluating, and fabricating novel biomaterials for use in encapsulation systems that enable clinical evaluation of Semma’s core cell technology. The candidate will have a strong background in biomedical and chemical engineering, and will possess micro- and / or nano-fabrication skillsets to be used in developing processes used in the manufacture of implantable devices. A working knowledge of GLP / GMP systems is desired as well as preclinical development experience.

Under the supervision of the Director of Device Development, the scientist will also be expected to play an integral role in manufacturing validation. The position will be located in Providence, RI.

Required qualifications:

MS or PhD in biomedical engineering, chemical engineering, or related discipline
Medical device manufacturing experience
Experience working in a cleanroom environment
Demonstrated translation of research into defined processes and associated SOPs
Exhibits capability in planning, executing, and analyzing experiments
Able to troubleshoot, solve difficult problems, and develop process improvements
Attention to detail and careful record-keeping
Excellent organizational skills and ability to manage multiple projects
Excellent oral and written communication skills, able to write technical reports and protocols
Flexible team player excited to collaborate with internal and external partners
Highly self-motivated
Flexibility in working schedule to accommodate weekend work
Preferred qualifications:

Experience in evaluating biomaterials in animal models
Previous experience and knowledge of pancreatic islet biology and diabetes
Experience in regulatory submissions


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Pre Clinical Biology Scientist Neuroscience Epilepsy

Date Posted:
3/17/2017

Ovid

NY

Ovid’s pipeline is expanding rapidly, necessitating growth of the research team. This incoming scientist will work with contract research organizations, and in some instances academic collaborators, to test specific experimental hypotheses relating to in-house assets. Extensive hands-on experience carrying out neuroscience research is essential. This background will enable:

RESPONSIBILITIES

Rapid familiarization with disease related literature and appropriate model systems
Development of appropriate detailed research protocols (in collaboration with internal research team and external parties)
Day to day oversight of external activities and progress
Interpretation and communication of results to the internal team
REQUIREMENTS

Extensive hands on experience carrying out neuroscience research, either in an academic or industry setting, is a must. She or he should have an MSc or preferably a Ph.D. in biochemistry, molecular biology, neuroscience or a related field. Expertise in electrophysiological research techniques and a background in pediatric epilepsies is highly desirable.

The successful candidate will be internally motivated, comfortable working independently, and strive to proactively mitigate risks. The desire to be in a rapidly changing start-up environment is also necessary.

CONTACT

Kristen Alexander | Talent Acquisition & Engagement | Ovid Therapeutics kalexander@ovidrx.com

 


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Scientist/Sr. Scientist Immunooncology

Date Posted:
3/17/2017

CRIPSR

MA

Scientist / Sr. Scientist, Immuno-Oncology

If interested and qualified, please include Requisition # 2017-106 in the subject line when emailing resume to: careers@crisprtx.com.

For more information on CRISPR Therapeutics, please click here.

Position Summary

We are seeking a Scientist who will lead efforts in developing novel CRISPR-based therapeutics for oncology. The successful candidate will help build a pipeline of immuno-oncology products and will have expertise in biologic therapeutics in oncology as well as an understanding in immunology. The position requires enthusiasm, passion, attention to detail, and a commitment to improve the lives of those afflicted with cancer.

Responsibilities

Establish a pipeline of CRISPR-based therapeutics for oncology including CAR T based therapies
Conceive, design and perform experiments
Collaborate with and serve as scientific mentor to assigned Research Associates, directing the work of Research Associates at the laboratory bench as necessary
Assist company in securing IP from research program discoveries, including detailed descriptions for patent filing and/or proof of concept work, as appropriate appropriate
Minimum Qualifications

PhD in a related scientific discipline and with 0-3 years of postdoctoral experience
Experimental knowledge of immune cells, particularly in the functional characterization of T cells
Experience with antibody engineering
A strong track record of intellectually challenging oneself to enhance scientific capabilities
Scientifically rigorous, highly organized, and with significant attention to detail
Excellent oral and written communication skills
Ability to work independently as well as collaborate with peers and effectively work in a results oriented research team environment
Preferred Qualifications

Knowledge of the pathophysiology and treatment of cancer
High energy level, focus, a passion and sense of urgency for developing important new medicines for devastating diseases
Competencies

Problem Solving – The ability to understand a situation, task or problem by breaking it down into smaller pieces using a systematic approach and to identify patterns and connections between situations that are not obviously related.
Scientific Rigor/Attention to detail – Maintains high scientific rigor and attention to detail in designing and testing hypotheses and analyzing data. Challenges assumptions, demonstrates highly organized thinking and documentation.
Creativity/Innovation – Creates a boundary-less environment that fosters curiosity and taking risks, is able to test, confirm or refute scientific hypothesis effectively and efficiently. Open to new approaches, alternative points of view and methodologies. Able to be opportunistic.
Leadership – The ability to take the role as a leader of a team or work group.
Communication and Teamwork – Effectively expresses ideas in written, visual, and oral context. Able to work co-operatively with others; the genuine desire to be a part of a team and contribute to organizational and team goals.
Passion – Creates an exciting environment where there is a true passion for the vision of CRISPR Therapeutics to bring novel medicines to patients suffering from serious diseases.
If interested and qualified, please include Requisition # 2017-106 in the subject line when emailing resume to: careers@crisprtx.com.

 


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Computational Biology Scientist

Date Posted:
3/17/2017

CRISPR

MA

Computational Biology Scientist

If interested and qualified, please include Requisition # 2017-107 in the subject line when emailing resume to: careers@crisprtx.com.

For more information on CRISPR Therapeutics, please click here.

Position Summary

We are seeking a talented Computational Biologist / Bioinformatics Scientist to tackle challenging bioinformatics and computational biology problems and work collaboratively with research groups to build the tools, algorithms, and pipelines required to support the development of new, transformative CRISPR/Cas9-based gene editing therapies.

Responsibilities

Develop and implement computational biology tools and programs to support all gene editing and research activities
Balance integration and extension of existing bioinformatics and next generation sequencing tools with the creation of new tools and algorithms as dictated by projects and problem contexts
Design and code web tools for data analysis and integration in close interaction with researchers and with a strong focus on the researchers’ needs
Produce high-quality code that is optimized for performance and scalability and adherence to coding best practices
Help identify test cases, resolve issues, and fix bugs
Give accurate time estimates based on verbal and written specifications
Minimum Qualifications

Degree (Ph.D. or equivalent) in quantitative or basic science (computer science, computational biology / bioinformatics, chemistry, physics, mathematics, or applied science preferred)
Experience (new graduate or post-doc) with background in creating, managing, analyzing genome scale data and / or tools as for example: microarray or next generation sequencing (NGS) including whole genome, exome, RNA-seq, ChIP-seq, methylation sequencing (RRBS)
A solid grasp of R and/or Python is essential for success with other languages such as Java, C++, MATLAB also helpful
Ability to work independently and successfully in a matrix environment, prioritize and manage multiple tasks simultaneously, integrate cross-functional issues and balance competing priorities effectively
Good writing skills including documentation skills to maintain software and support documentation
Preferred Qualifications

Advanced degree (Ph.D., or equivalent) or significant work experience (0-2 years’ experience)
The ideal candidate will be a software engineer or computational biologist that can think from the point of view of a biologist while understanding computer science / software engineering at a deep level; very close interaction with molecular / cell biologists will be expected at every level from tool / algorithm design, curation / quality control, analysis, and code testing to ultimately delivering algorithms and tools (Bioinformatics Software Engineer) or insights and recommendations (Computational Biologist) to other researchers and decision makers
Wide understanding of both biology and computational biology
Experience working in fast paced team environments (industry and start-up experience is a plus)
Ability to understand and make decisions and recommendations about high level strategy as well as about the details of an analysis project or experiment
Extensive experience in bioinformatics, software engineering / testing / validation, data curation, large scale data and NGS analysis, statistics, or statistical model building, as evidenced by productive and successful programs and/or publications
Experience with Git, R Markdown / LaTeX
Cloud compute experience (AWS)
Strong leadership and management skills, excellent verbal and written communication
Familiarity with cell and molecular biology techniques, NGS, gene editing and/or CRISPR/Cas9 biology
A high degree of energy, accuracy and attention to detail, and a passion for creating transformative gene-based medicines to patients with serious diseases
Competencies

Approachability – Is easy to talk to, builds rapport well, and makes extra effort to put others at ease.
Listening – Practices active, patient listening. Has the ability to restate and consider a differing view, even when not in agreement.
Problem Solving – The ability to understand a situation, task or problem by breaking it down into smaller pieces using a systematic approach and to identify patterns and connections between situations that are not obviously related.
Creativity/Innovation - creating a boundary-less environment that fosters curiosity and taking risks, openness to new approaches, diversity of new thought, blank page creativity and opportunistic thinking.
Perseverance – Pursues tasks with energy, drive and initiative, even in the face of adversity.
Results Oriented – Drives issues to closure and gets the job done.
Communication and Teamwork – The ability to effectively express ideas in written and oral context. The ability to work cooperatively with others; the genuine desire to be a part of a team and contribute to organizational and team goals.
If interested and qualified, please include Requisition # 2017-107 in the subject line when emailing resume to: careers@crisprtx.com.

For more information on CRISPR Therapeutics, please click here.


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Postdoc GENIE

Date Posted:
3/17/2017

HHMI

VA

Janelia Research Campus (Janelia) supports large, multidisciplinary projects in neurobiology and imaging. The GENIE (Genetically-Encoded Neuronal Indicator and Effector) project produces thousands of molecular constructs per year, with the goal of creating highly sensitive calcium and voltage indicators, to increase the sensitivity and resolution of imaging and analysis of functional neural systems. Constructs are screened in tissue culture assays. Promising candidates are then calibrated and tested in vivo in transgenic Drosophila and other model systems.

The Research Specialist will be a hands-on independent researcher, responsible for taking promising hits from earlier phase screening efforts, characterizing their performance and potential toxicity in vivo in Drosophila larvae and adults, and correlating sensor signals with electrophysiological recordings using electrical and/or sensory stimulation.



Essential Duties and Responsibilities:

Perform in vivo optical imaging in Drosophila larval neuromuscular junction (NMJ) using fluorescence microscopy. Stimulate activity at the NMJ using suction electrodes and use statistical analysis to correlate resulting sensor signal with action potentials.
Perform simultaneous optical imaging and electrophysiology in the central brain of intact adult flies under sensory stimulation. Test sensor effects on normal responses of identified neurons, and correlate sensor signal with action potentials recorded using patch clamp recordings.
Modify biological preparation, instrumentation and analysis routines as necessary to test calcium and voltage indicators.
Perform other related duties as required.


Scope:

Will not have personnel management responsibilities.


Preferred Qualifications:

Education / Experience:

Ph.D. or M.S. in Neuroscience, Biophysics, or related discipline.
5 years experience with fluorescence microscopy and analysis techniques. Two-photon microscopy experience a plus.
Demonstrated experience with intracellular electrophysiology. Patch clamp recording experience a plus.
Significant experience with larval or adult fly physiology.
Data analysis skills (proficiency in MATLAB or similar analysis environment preferred).
Excellent communication skills.

Skills and Abilities:

Ability to perform extensive hands-on work at the bench, with minimal supervision.
Ability to fully document and substantiate scientific methods, procedures, and results.
Ability to manage and analyze large data sets.
Computer skills for image and statistical analyses, document preparation, database management, and presentations.

Physical Requirements:

Occasionally lifts and/or carries objects weighing up to 20 pounds.
Occasionally stoops and bends.
Occasionally reaches and grasps with arms and hands.
Work involves possible exposure to malodorous vapors, animal allergens and other animal-borne hazards, experimental microbial agents, low dose radiation, contamination by toxic chemicals and acids and presence of carcinogenic substances.
Long periods of standing and/or sitting.
Job Location
Ashburn, Virginia, United States
Position Type
Full-Time/Regular


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Research Specialist or Postdoc MultiFISH

Date Posted:
3/17/2017

HHMI

VA

Howard Hughes Medical Institute (HHMI) is a science philanthropy whose mission is to advance biomedical research and science education for the benefit of humanity. We empower exceptional scientists and students to pursue fundamental questions about living systems, and work to share scientific discoveries with researchers, students, and science-curious individuals around the world.

Founded in 1953 by aviator and industrialist Howard R. Hughes, HHMI is headquartered in Chevy Chase, Maryland, and employs more than 2,500 people across the U.S. Visit hhmi.org/careers to learn more about working at HHMI.

About Janelia
Janelia Research Campus is a pioneering research center in Ashburn, Virginia, where scientists pursue fundamental questions in neuroscience and imaging. The Howard Hughes Medical Institute (HHMI) launched Janelia in 2006, establishing an intellectually distinctive environment for scientists to do creative, collaborative, hands-on work. The Janelia Research Campus is a unique, world-class research institute with a major focus on the development of cutting-edge imaging and analysis tools. We prize collaboration and in addition to supporting independent laboratories, we support a unique ecosystem of Project Teams to tackle experimentally challenging problems at scale. To learn more about working at Janelia, visit janelia.org/careers.

Summary
The Howard Hughes Medical Institute's Janelia Research Campus is looking for an outstanding Research Specialist or Postdoctoral Associate interested in developing new methods for highly multiplexed imaging of RNA in neural tissue, using the Expansion Microscopy technique for physically expanding tissue by embedding in a swellable gel. The MultiFISH project team is a new effort to combine new molecular and imaging methods in order to develop a robust protocol for multiplexed RNA Fluorescence In Situ Hybridization (FISH). This protocol will be made readily available to research groups at Janelia and in the broader neuroscience community. The broader goal is to enable studies that combine in vivo experiments with post-fixation molecular characterization of the same tissue. We seek a candidate interested in developing new methods and helping to develop a robust protocol including tissue handling, probing, and imaging. This is a highly collaborative position with opportunities to interact with the Tillberg, Sternston, Svoboda and Lavis Labs. Individuals interested in pursuing an academic research career or a specialist with experience in histology and/or optical imaging are encouraged to apply.

Principal Responsibilities:
Develop cutting edge hydrogel tissue embedding methods.
Carry out RNA Fluorescence In Situ Hybridization (FISH), high content imaging, and spectral unmixing in thick brain tissue slices.
Work collaboratively with a team of scientists to develop a protocol for multiplexed RNA FISH in thick tissue slices suitable for routine use in neuroscience experiments.

Preferred Qualifications:
PhD in Engineering, Bioengineering, Biology, Neuroscience or a related discipline
Strong background in optical imaging and image processing using large imaging datasets
Experience with RNA Fluorescence In Situ Hybridization (FISH) useful but not necessary
Ability to work as part of a team
Ability to develop novel approaches


HHMI is an Equal Opportunity Employer.
Job Location
Ashburn, Virginia, United States


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Research Specialist I metabolomics

Date Posted:
3/17/2017

HHMI

TX

Dr. Sean J. Morrison, HHMI Investigator and Director of the Children’s Research Institute at the University of Texas Southwestern Medical Center (CRI) invites applications for RESEARCH SPECIALIST positions to apply metabolomics methods to the study of stem cell metabolism.

We seek scholars with Ph.D. or equivalent degrees and demonstrated scientific accomplishment, who exhibit the potential to perform outstanding research in metabolomics. The primary responsibility of the Research Specialist will be to develop and implement metabolomic profiling methods using an AB SCIEX 5500 QTRAP LC/MS/MS and an Agilent 6550 iFunnel Q-TOF LC/MS. Applicants should have experience with method development, including preparation of biological samples, chromatographic separation, mass spectrometry and data analysis. Key ongoing projects using the facility involve analyzing the abundance and isotopic enrichment of informative metabolites in human plasma, tumor tissue and primary hematopoietic stem cells from mice. NMR spectroscopy, 13C dynamic nuclear polarization and a state-of-the-art mouse metabolic core facility are also available on campus to complement metabolomics studies and to provide an unparalleled breadth of metabolic analysis.

Applicants should provide a curriculum vitae, a one page summary of research experience, and a list of references when submitting the online application.


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Research Specialist I

Date Posted:
3/17/2017

HHMI

WI

Job Description
At the Howard Hughes Medical Institute (HHMI), creativity and excellence are fundamental to our success. As one of the world's largest philanthropies, HHMI is a major force in advancing biomedical research and science education in the U.S. and beyond.
Perform professional work in support of scientific research. Working collaboratively with the Investigator, determine the most suitable methods to be used in research. Independently perform scientific investigative procedures requiring application of professional judgment. Interpret experimental results and determine whether they are consistent with experimental goals. Review pertinent literature for information that will further research goals. Prepare reports of research for presentation or publication.
Required Skills
Perform various specialized scientific investigative procedures in support of assigned research projects.
Develop transgenic technologies for planarian flatworms.
Generate gene knock-outs and knock-in reporter lines.
Independently design and conduct experiments under the supervision of Principal Investigator.
Conduct literature reviews to be used in determining most suitable research methods.
May configure, operate, and/or maintain specialized equipment.
Identify methodological problems in research protocol and assist in implementing modifications to optimize experimental results.
Coordinate specialized and novel research functions.
May use software applications to assemble, manipulate, format and/or perform statistical analyses of data.
Prepare and present written or oral progress reports concerning studies, including assembly, organizational and interpretation of data.
Present data to the Principal Investigator (monthly progress reports), to the entire lab (lab meetings ~1-2 times a year), and occasionally at scientific meetings.
Train others in complex technical protocols.
Shares significant responsibility for results of research project or project team. Manages own research project with input of the Investigator. Intermediate to long term impact on results of entire lab.
Successful candidate has the chance to work in the exciting and rapidly expanding field of planarian regeneration with a diverse group of talented and dedicated scientists.
Play a vital collaborative role in the Newmark lab and actively contribute to research efforts of other lab members.
Establishes intermediate range goals and schedules work to meet those goals. Work is reviewed at key stages by supervisor but individual is largely self-directed. May monitor performance of others and provide or propose required training. May develop, or lead the development of, training tools. May plan for and provide working supervision to a group of laboratory employees of lower grade engaged in the performance of technical and professional work and a variety of complex to routine to complex tasks.

Required Experience
Ph.D. (currently or by May 2017) with experience in molecular biology.
Expertise in generating transgenic lines, preferably at the organismal level.
Knowledge of or experience with current CRISPR/Cas9 technologies.
Experience with viewing and analyzing genomic/transcriptomic sequence data.
Excellent oral communication and interpersonal skills.

Please include the answers to the following questions in your cover letter:
Do you have any experience with transgenic technologies?
In what experimental system?
How familiar are you with CRISPR/Cas9?
Job Location
Madison, Wisconsin, United States
Position Type
Full-Time/Regular


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NMR Research Specialist

Date Posted:
3/17/2017

HHMI

MA

The Howard Hughes Medical Institute currently has an opening for a PhD-level NMR scientist to join Dr. Dorothee Kern’s laboratory as a Research Specialist. This unique position, in the Department of Biochemistry at Brandeis University (located 10 miles west of Boston MA), is suitable as a partnership with Dr. Kern. It offers the opportunity to collaborate with a variety of cutting-edge scientists within the Brandeis University community.

Dr. Dorothee Kern uses biophysical analytical techniques to unravel the dynamic personality of enzymes, signaling proteins, and the molecules they affect. The NMR Research Specialist will be responsible for overseeing NMR spectroscopic activities including training of graduate students and postdocs. You will also be responsible for implementing and optimizing new pulse programs.

The laboratory is equipped with Inova Varian 600, 500 and 400 MHz NMR spectrometers, and a Bruker Advance II 800 MHz spectrometer with cryoprobe. 900 MHz spectrometers are available in Boston and at UC Boulder. Brandeis University provides significant personnel support for hardware management and maintenance that will allow you to focus on advanced scientific studies.

The Research Specialist position provides PhD-level scientists the opportunity to work in a stimulating academic research environment and to continue their scientific development. You will collaborate on exciting ongoing work with lab members and have the opportunity to establish an independent research project.

To apply for this position, click on the link below. Please submit a cover letter, attn: Charlene Tribbett-Talley, that includes three references, along with your resume/CV.
Required Skills
Partner with PI to help achieve long-term goals for the laboratory by working with lab members and collaborators.
Day-to-day interactions with graduate students and post-docs to provide guidance and refine NMR techniques.
Develop and provide NMR training to lab personnel as needed.
Monitor progress of projects and suggest improvements.
Keep up-to-date on advances in the field by reading the literature and attending meetings.
Use up-to-date knowledge to evaluate approaches and technologies and make recommendations for improvements to achieve research goals.
Work with the PI to review operational needs of NMR activities, and develop and implement intermediate and long-term goals.
Conduct experiments tailored to the goals of the lab and the experience of the candidate.
Required Experience
Ph.D. in Biochemistry, Physics, Biosphysics or Chemistry with postdoctoral experience preferred.
Proven track record in high-resolution biomolecular or solid-state NMR.
Highly advanced knowledge in NMR spectroscopy
Strong verbal and written communication skills.
Excellent interpersonal skills.
Ability to develop innovative processes to achieve goals.
Must be a dedicated and independent thinker with strong research and organizational skills.
This position will require a driven, creative individual who is willing to tackle novel challenges and continually work towards process improvement.


HHMI is an Equal Opportunity Employer
Job Location
Waltham, Massachusetts, United States


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Postdoc molecular biology

Date Posted:
3/17/2017

HHMI

WI

At the Howard Hughes Medical Institute (HHMI), creativity and excellence are fundamental to our success. As one of the world's largest philanthropies, HHMI is a major force in advancing biomedical research and science education.

The Ahlquist laboratory at the University of Wisconsin-Madison is recruiting a post-doctoral researcher to study the molecular mechanisms of viral and host interactions in positive-strand RNA virus genome replication. Projects include multiple aspects of the structure, assembly and function of viral RNA replication complexes, which are fascinating molecular machines and major targets for virus control. These highly synergistic studies integrate cutting-edge molecular genetics, biochemistry, cell biology, and cryo-electron microscopy with bioinformatics and computational biology.

Successful candidates will join a dynamic, multidisciplinary team with diverse backgrounds and expertise in a well-equipped, interactive research environment on the campus of the UW-Madison. We offer an extraordinary work environment built around a multi-disciplinary fusion of ideas, state-of-the-art facilities, and commitment to mentorship. UW-Madison consistently ranks among the top U.S. universities for research and development and the City of Madison among the 'best places to live in the US' with a diversity of outdoor and cultural opportunities.


Additional Information

For more information, please see:
http://www.hhmi.org/scientists/paul-ahlquist
http://mcardle.wisc.edu/bio/ahlquist_p.html


To Apply

Qualified candidates interested in this opportunity are required to submit a single pdf document containing their CV and a cover letter detailing their current/previous research and names/address of three references as one document to

Johan den Boon
Associate Scientist
email: JdenBoon@morgridge.org



HHMI is an Equal Opportunity Employer


Required Skills
Candidates should have a Ph.D. in cell and molecular biology, genetics, biochemistry, microbiology, or a related field, and proven research productivity as demonstrated by publications. The ideal candidate will be a highly motivated, creative person with the ability to learn quickly and function both independently and within a team, and with excellent written and oral communication skills.

Job Location
Madison, Wisconsin, United States


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Postdoc HIV

Date Posted:
3/17/2017

HHMI

NY

Job Description
The laboratory of Dr. William R. Jacobs, Jr. of the Howard Hughes Medical Institute at the Albert Einstein College of Medicine/Montefiore Medical Center is seeking a highly motivated and innovative post-doctoral scientist interested in the development of vaccines against Tuberculosis and HIV using a novel recombinant Herpes Simplex Virus-2 (HSV-2) ΔgD vaccine vector (Petro, C., Gonzalez, P. et al. 2015 eLife PMID 25756612; Petro et al. 2016 JCI Insight PMID 27536733). The project will involve mechanistic analyses with the aims of exploring the use of vaccine vectors that elicit high titer FcR activating ADCC antibodies to provide protection against HIV and Mycobacterium tuberculosis. This work will be conducted in collaboration with Dr. Betsy Herold, Pediatric Infectious Diseases and Microbiology-Immunology at Einstein/Montefiore.
Required Skills
Job Requirements:

Applicants must have a PhD, MD, or equivalent degree, with a track record of research excellence, and expertise in genetic manipulation of Herpes viruses or M. tuberculosis, immunological analyses or animal infection models. Qualified applicants should submit a cover letter, curriculum vitae, and a brief summary of research accomplishments and goals in a single PDF document to jacobsw@hhmi.org. Applicants should also arrange to have three letters of reference sent directly to this email address.

The Albert Einstein College of Medicine is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information. Einstein seeks candidates whose skills, and personal and professional experience, have prepared them to contribute to our commitment to diversity and excellence, and the communities we serve.


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Postdoctoral Fellow neuroscience electrophysiology

Date Posted:
3/17/2017

HHMI

WI

Howard Hughes Medical Institute (HHMI) is a science philanthropy whose mission is to advance biomedical research and science education for the benefit of humanity. We empower exceptional scientists and students to pursue fundamental questions about living systems, and work to share scientific discoveries with researchers, students, and science-curious individuals around the world.

Founded in 1953 by aviator and industrialist Howard R. Hughes, HHMI is headquartered in Chevy Chase, Maryland, and employs more than 2,500 people across the U.S. Visit hhmi.org/careers to learn more about working at HHMI.

The Chapman lab is looking for a highly motivated postdoctoral electrophysiologist to study aspects of neuroscience. Our lab is interested in Ca2+ regulated synaptic vesicle exocytosis, synaptic transmission and neuronal circuit activity. The successful candidate will conduct patch clamp experiments using cultured neurons and brain slices to measure synaptic depression, paired pulse facilitation, and other aspects of synaptic plasticity. Other goals are to: understand how the interplay between various organelles influences synaptic function, assign functions to synaptic vesicle and presynaptic proteins, probe the structure and function of fusion pores, and understand the factors that control oscillations in neuronal circuits. This postdoc researcher is also expected to contribute ideas, interact and collaborate with other lab members and other laboratories, and to prepare manuscripts for publication.

How to Apply
Please send you letter of interest, CV and publication list.

HHMI is an Equal Opportunity Employer
Required Skills
Requirements
A Ph.D. or equivalent degree in neuroscience or related discipline is required. A strong background in electrophysiology is essential for this position. Experience conducting patch clamp recordings in cultured neurons and brain slices is highly preferred.

Besides electrophysiology, the ideal candidate would also be familiar with imaging (of Ca2+, pHluorin, etc.) or optogenetics, and other regular lab skills in a biomedical research group.

Analysis of electrophysiology and image data.

Self-motivated, able to work independently and as part of a team.

Strong verbal and written communication skills.

Job Location
Madison, Wisconsin, United States
Position Type
Full-Time/Regular


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Postdoctoral Fellow Neurogenesis

Date Posted:
3/17/2017

HHMI

CA

At the Howard Hughes Medical Institute (HHMI), creativity and excellence are fundamental to our success. As one of the world's largest philanthropies, HHMI is a major force in advancing biomedical research and science education in the U.S. and beyond.

We have an exciting postdoctoral position available in the Chang lab at the University of California, Berkeley. The Chang lab studies the molecular roles of metals and redox-active small molecules relevant to human health, focusing on the physiology of brain, immune, and fat systems and how they are compromised in aging and disease.

Principal Responsibilities:

The ideal candidate will be responsible for studying the role of redox signaling in neurogenesis and neural plasticity.
For information on Prof. Chang’s lab click on the research abstract link above or visit: http://www.hhmi.org/research/metals-and-redox-biology

Preferred Qualifications:

Applicants must have a PhD in Molecular and Cell Biology, Neurosciences or other related fields with a strong academic record demonstrated by publications in peer-reviewed journals.
Experience in mammalian cell culture, primary cell and slice culture, RNAi, viral transfection, and confocal imaging is required.
Experience in mouse genetics, stereotactic surgery, brain slice preparation, electrophysiology, functional imaging, high-throughput screens, and super-resolution imaging is highly desirable.
Highly motivated individual that can work autonomously and with a team of scientists from diverse backgrounds.

Additional Information:
Interested candidates should send a single PDF with a cover letter, CV, and names of three references to Christopher Chang, PhD at chang.berkeley.hhmi@gmail.com. Please include the job title in the subject line.

To Apply

To apply for this position, please email your resume to:

Chris J. Chang, PhD
Investigator

E-mail: chang.berkeley.hhmi@gmail.com


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Postdoctoral Fellow Physiology Lipid Metabolism

Date Posted:
3/17/2017

HHMI

MA

At the Howard Hughes Medical Institute (HHMI), creativity and excellence are fundamental to our success. As one of the world’s largest philanthropies, HHMI is a major force in advancing biomedical research and science education.

We have a postdoctoral position available in the laboratory of HHMI Investigator, Tobias Walther, Ph.D., and Robert V. Farese, Jr, M.D., who jointly run a highly collaborative group at the Harvard School of Public Health. The lab is located in the Boston Longwood medical campus and is affiliated with the Department of Genetics and Complex Disease (HSPH), the Department of Cell Biology (Harvard Medical School), the Broad Institute of MIT and Harvard, and the Howard Hughes Medical Institute.

The Walther-Farese Laboratory studies the biochemistry of cellular lipid metabolism and membrane homeostasis. We seek outstanding candidates with Ph.D. training in physiology and in vivo models of lipid metabolism. Projects are available in the areas of fatty acid, cholesterol and sphingolipid homeostasis.

Applicants should possess a Ph.D. or M.D./Ph.D. in cell biology or neurodegenerative disease research and have an outstanding publication record.

For additional information, please visit our webpages:
https://faresewaltherlab.hms.harvard.edu
http://cellbio.med.harvard.edu/people/faculty/farese-jr
http://cellbio.med.harvard.edu/people/faculty/walther
https://www.hhmi.org/scientists/tobias-c-walther

To Apply
Interested candidates should send a cover letter, Curriculum Vitae and three letters of reference to: robert@hsph.harvard.edu and tholmes@hsph.harvard.edu. Please include the position title in the subject line.
Job Location
Boston, Massachusetts, United States
Position Type
Full-Time/Regular


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Postdoctoral Fellow Cellular Neurodegeneration

Date Posted:
3/17/2017

HHMI

MA

At the Howard Hughes Medical Institute (HHMI), creativity and excellence are fundamental to our success. As one of the world’s largest philanthropies, HHMI is a major force in advancing biomedical research and science education.

We have a postdoctoral position available in the laboratory of HHMI Investigator, Tobias Walther, Ph.D., and Robert V. Farese, Jr, M.D., who jointly run a highly collaborative group at the Harvard School of Public Health. The lab is located in the Boston Longwood medical campus and is affiliated with the Department of Genetics and Complex Disease (HSPH), the Department of Cell Biology (Harvard Medical School), the Broad Institute of MIT and Harvard, and the Howard Hughes Medical Institute.

The Walther-Farese Laboratory studies the biochemistry of cellular lipid metabolism and membrane homeostasis. We seek outstanding candidates with Ph.D. training in cellular and murine models of neurodegeneration. Projects are available in the areas of lyososome biology and frontotemporal dementia and in the area of altered sphingolipid homeostasis and neurodegenerative diseases.

Applicants should possess a Ph.D. or M.D./Ph.D. in cell biology or neurodegenerative disease research and have an outstanding publication record.

For additional information, please visit our webpages:
https://faresewaltherlab.hms.harvard.edu/
http://cellbio.med.harvard.edu/people/faculty/farese-jr
http://cellbio.med.harvard.edu/people/faculty/walther
https://www.hhmi.org/scientists/tobias-c-walther

To Apply
Interested candidates should send a cover letter, Curriculum Vitae and three letters of reference to: robert@hsph.harvard.edu and tholmes@hsph.harvard.edu. Please include the position title in the subject line.
Job Location
Boston, Massachusetts, United States
Position Type
Full-Time/Regular


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Human Subjects and Clinical Trials Specialist

Date Posted:
2/10/2017

NIH/Ripple Effect Communications

MD

Position Description:
The National Institutes of Health (NIH) is the nation's premier biomedical research agency. Within the Office of Extramural Research (OER), the Office of Extramural Programs (OEP) provides leadership for the management of trans-NIH programs via the development of programs and policies, interpretation, coordination, oversight, evaluation, training and outreach for NIH extramural staff and the extramural research community. As such, OEP is tasked with helping to provide oversight and direction for the implementation of initiatives aimed at enhancing the stewardship, accountability, and transparency of clinical trials. Several recent initiatives, including the NIH policy on dissemination of clinical trials information, the single IRB policy, and the new 21st Century Cures bill will necessitate major changes for NIH. Ripple Effect is seeking a full-time staff member to work with OEP and other NIH components to implement initiatives to enhance the stewardship of clinical trials. This is a 1-year appointment with the possibility of an extension.

Background:
Ripple Effect attracts high-achievers who consistently attain above-average results and take responsibility for solving problems. Our clients engage us because we bring intelligence, innovation, initiative, and impact to project management. We need self-starters who get the job done, who can handle a wide range of support tasks, and who enjoy the energy of a government office with intelligent colleagues and fast-paced programs.

Job Description:
Apply if you're looking for a job that delivers these opportunities:

  • Contribute to high-level functioning within a government agency
  • Interact professionally with government clients
  • Think on your feet while mastering new tasks quickly and independently

Preference will be given to individuals who are performing at this level successfully. Job offer is contingent upon task order award.
The Program Manager will provide program administration and subject-matter expertise by completing the following tasks:
Task 1: Provide subject matter expertise

  • Advise OER on optimal approaches to implementation of clinical trials and privacy related policies and regulations.
  • Provide technical expertise in the development of new or revised products (policies, guidance, instructions, procedures resources, etc) needed for oversight of the NIH clinical trials policies and procedures
  • Provide technical expertise in the development of new or revised products (draft regulations, policies, guidance, instructions, procedures resources, etc) for NIH privacy protections programs and/or certificates of confidentiality
  • Use expertise to assess products proposed by others in OER, NIH, and the extramural research community
  • Prepare reports that reflect current state-of-the-art on topics in areas of expertise to help guide OER decisions

Task 2: Program Management

  • Use the appropriate project management processes, skills, and resources to oversee projects pertaining to clinical trials and privacy.
  • Employ techniques to define, plan, organize, schedule, budget, manage and close out projects
  • Oversee and manage project teams (e.g., coordinate subgroups to ensure tasks are ongoing and completed on time)
  • Formulate, organize and monitor inter-connected projects
  • Resolve higher scope issues
  • Manage stakeholder expectations
  • Prepare supporting documents for clearance requests

Task 3: Program Support

  • Represent OEP positions at meetings within and external to NIH.
  • Provide program support to OEP on related extramural initiatives

Qualifications:

  • Possess a Master's degree or higher from an accredited university
  • Have adept skills and knowledge of Microsoft Office tools (i.e., Word, Excel, PowerPoint, SharePoint)
  • Have a working knowledge of program/project management software (e.g., MS SharePoint, Basecamp, MS Project etc.)
  • Possess excellent problem-solving and communication skills
  • Have experience in project or program management
  • Have knowledge and understanding of the management and conduct of clinical trials (preferably NIH clinical trials), including knowledge of privacy protection regulations and certificates of confidentiality
  • Have a scientific background acquired via education, training and/or experience
  • Experience with NIH preferred, particularly the extramural research programs
  • Be willing and able to work full time on the client site during core business hours

To Apply:
Please apply to this position directly on the Ripple Effect website. In case needed, here is the direct link for the application:https://ripple-effect-communications-inc.workable.com/jobs/416594


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Laboratory Manager

Date Posted:
3/17/2017

HHMI

TX

To manage a large, high-paced laboratory and to participate in conducting research on stem cells from the nervous and hematopoietic systems. Qualified applicant will be expected to provide advice, assistance, and supervision to graduate students and postdoctoral fellows in the laboratory. In addition, this individual would also be responsible for the overall management of the laboratory, in conjunction with the principal investigator, and other technical and administrative support staff.

The successful candidate would provide senior-level technical lab support and act as a specialist on laboratory methods and equipment functions. The successful candidate would be able to instruct lab members in techniques, instrument utilization, methods, and procedures as well as interact with university regulatory staff to ensure the laboratory meets all regulatory standards.

MINIMUM QUALIFICATIONS:
Masters or Ph.D. degree in biological/biomedical science and 5-6 years of experience in some area of biomedical research. Previous research experience is required.

DESIRED QUALIFICATIONS:
Experience in laboratory management in the fields of molecular, cellular, and/or developmental biology.


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Postdoctoral Fellow Computational Biology

Date Posted:
3/17/2017

Jackson Labs

CT

About JAX-GM: Comprising 183,000 square feet of highly advanced, state-of-the-art laboratories and supporting facilities, the brand new JAX-GM conveniently sits midway between NYC and Boston in the heart of Connecticut. JAX-GM is part of an exciting $1.1 billion venture between the state of Connecticut and The Jackson Laboratory, an internationally-recognized research and educational institution with unparalleled genomic resources and research support services.
About the position: A postdoctoral research position in computational biology is available in Principal Investigator Sheng Li’s lab at the Jackson Laboratory for Genomic Medicine. The goal of the Li Lab is to contribute to the development of novel therapies that address cancer evolution. Our research focuses primarily on (1) understanding the epigenome dynamics during cancer evolution over time and under therapy; and (2) the mechanisms and translational implications of cancer cells population heterogeneity and plasticity.
We are looking for applicants who are excited to work in the creative and dynamic environment ingrained in JAX’s collegial, collaborative, interdisciplinary, and diverse research culture.
Key Responsibilities
The postdoctoral researcher is expected to develop new analytical methods for cancer epigenome/transcriptome data integration, and to analyze bulk and single-cell sequencing data sets from clinical studies.
Minimum Qualifications
PhD in a statistics, biostatistics, computer science, physics, computational biology, bioinformatics, or a related field with knowledge of statistics
A strong computational background (proficiency in at least one programming language required)
Excellent communication skills and fully fluent spoken and written English
A passion for solving cutting edge research problems of computational biology
The Following Optional Qualifications Are Considered Advantageous
Knowledge of (and/or work experience with) machine learning methods
Experience with large-scale data analysis using software pipelines in an HPC environment
Experience in software development
Research experience in next-generation sequencing data analysis and utilization of public available bioinformatics resources
More About Jax
JAX began in 1929 with a small group of scientists dedicated to the emerging field of genetics. We now have over 1700 scientists, technicians, and support staff, including over 50 Principle Investigators in five primary disease areas: cancer, reproductive biology, immunology, metabolic processes, and neuroscience. Our fundamental contributions to biomedical research include cancer genetics and establishing the mouse as the premier research animal model.
Uncover more of our historic milestones, including the 26 Nobel prizes associated with our research, resources, & education
Read our latest news & insights for a glimpse at how we’re impacting the future of biomedicine
Follow the progress we’re making on our quest to improve human health via our recent research highlights


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Research Fellow Psychiatric Diseases

Date Posted:
3/17/2017

Partners Health Care

MA

McLean Hospital is a comprehensive psychiatric hospital committed to providing easy access to superior quality, cost-effective mental health services in the Boston area, Massachusetts and beyond. Since 1811, McLean Hospital has been a world leader in the treatment of mental illness and chemical dependency, research into the cause of mental illness and the training of generations of mental health care providers. McLean's multidisciplinary programs treat a broad range of psychiatric illnesses across the full continuum of care.
General Summary
Psychosis Neurobiology Laboratory, Psychotic Disorders Division (McLean Hospital and Harvard Medical School) is seeking a research scientist to perform neurophysiological and computational modeling analyses of psychiatric diseases – acquiring and analyzing an array of biological and behavioral data to better understand the mechanisms and recovery trajectories for severe mental illness, particularly bipolar disorder and schizophrenia.
Data obtained in the lab include (1) an array of EEG and event-related potential responses (2) GWAS genotype, (3) structural brain imaging and brain biochemistry, (4) cognition, (5) functional recovery assessments, and (6) an array of clinical assessments. This position requires maintaining and extending data processing pipelines of longitudinal studies and applying explanatory computational models (data-driven) to test underlying brain and behavioral mechanisms and to develop optimize predictive models of outcome trajectories.
The candidate should have a background in neuropsychiatry, neuroscience, bioinformatics, biostatistics, computer and information science, or a related discipline (including data mining) with primary experience in apply/develop computational approaches for integrating/linking large datasets in psychiatry or neuroscience. Programming skills in Matlab, R, and Unix/Linux and scientific computing are highly desired. Secondary experience with image processing would be helpful.
The candidate will be based in the Psychosis Neurobiology Laboratory and Psychotic Disorders Division and will participate in studies with humans. In addition to the primary projects, research collaborations can be undertaken with interdisciplinary investigators in cognitive science, clinical service, and anxiety and depression among others. The selected candidate will also be encouraged to develop his/her own independent research projects.
Salary is commensurate with experience and excellent benefits are included. McLean is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment.
All McLean team members are expected to consistently demonstrate our values of integrity, compassion, respect, diversity, teamwork, excellence and innovation in their work activities and interactions.
Primary Location
MA-Belmont-McLean Hospital Main Campus
Work Locations
McLean Hospital Main Campus
Job
MD/PHD/Fellows/ PostDocs
Organization
McLean Hospital(MCL)
Schedule
Full-time
Standard Hours
40
Shift
Day Job
Employee Status
Regular
Recruiting Department
MCL Research
Job Posting
Mar 15, 2017
Required
PhD or MD in neuroscience, psychiatry, computer and information science, bioinformatics, statistics or related fields.
Candidates should have previously participated in research or performed relevant coursework in neurophysiology, psychiatric neurobiology, statistical or computational analyses.
Experience with EEG and/or neuroimaging data processing.
Preferred
Master degree or equivalent level education in biostatistics, bioinformatics, computer science, data science or other discipline requiring intense data analysis
1-3 years of experience in computational approaches for integrating across multiple data types to identify risk patterns and to develop predictive models.
Technology Statement
All employees must possess basic computer skills to use a variety of electronic or online systems for communication, clinical and administrative purposes.


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Research Scientist

Date Posted:
3/17/2017

Synaptics

CA

Synaptics is the pioneer and leader of the human interface revolution, bringing innovative and intuitive user experiences to intelligent devices. Synaptics’ broad portfolio of touch, display, and biometrics products is built on the company’s rich R&D and supply chain capabilities. With solutions designed for mobile, PC and automotive industries, Synaptics combines ease of use, functionality and aesthetics to enable products that help make our digital lives more productive, secure and enjoyable. (NASDAQ: SYNA)
Job Responsibilities
The R&D group at Synaptics is searching for a Biometrics scientist to develop technologies for next-generation biometric sensors and human / computer interfaces. This position reports to the Director of Advanced Development in the R&D group.
Independently execute on a research program in biometric sensors or human / computer interfaces
Communicate research progress and results
Transfer technology from research to development teams
Evaluate potential impact of different technologies on company’s core businesses
Required Qualifications
Master's degree in Engineering/Science; PhD preferred
10+ years of research experience with a demonstrated ability to create innovative technology and transfer from research to engineering development
Broad technical experience is essential. Skills in some or all of the following areas are necessary:
Human computer interfaces
Sensors
Optics
Image processing
Electrical engineering & signal processing
Systems engineering
Materials science
Physics
Mathematics
Excellent communication skills
Track record of publications / patents and presentations


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Medical Writer - Respiratory

Date Posted:
3/17/2017

health Interactions

NJ

Health Interactions is an international medical education agency providing innovative, high-quality and effective healthcare communications. As we are part of Nucleus Global, our clients benefit from the synergies available within our global network of offices staffed by highly talented individuals who can deliver on a global scale or a local level and across a broad spectrum of therapy areas.

Our success has led to continued expansion both in the range of services we offer and our global presence. We are now looking for a talented and enthusiastic Medical Writer.

This is your chance to work as part of a highly scientific team. This varied role involves writing accurate scientific / commercial copy for a range of printed and computer-based scientific materials from technical manuscripts to congress materials, interactive web projects and sales aids.

Working with leading international pharmaceutical clients, you will have the opportunity to interact with some of the world’s leading scientists and physicians on critical therapeutic and scientific issues. You will be required to participate in client meetings / teleconferences and attend scientific meetings such as congress, symposia and advisory boards and participate in pre-meetings, onsite activities and post meeting work as required / appropriate.

You should be passionate about communicating science to a variety of audiences and be able to add a creative edge and maintain quality standards. You will be interacting with some of the world’s leading scientists and physicians on critical therapeutic and scientific issues to make cutting-edge science accessible to those who need it.

To succeed you will have an advanced degree in the life sciences (PhD, MD or PharmD is mandatory). Previous relevant medical information, communications or marketing writing experience (agency or pharmaceutical) with specific expertise in respiratory is highly preferred. We also welcome candidates out of an academic environment with relevant research experience.


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Postdoc

Date Posted:
3/17/2017

Broad Institute

MA

Dr. Sekar Kathiresan's laboratory at the Broad Institute of MIT and Harvard seeks to hire a highly motivated postdoctoral fellow. The Kathiresan Lab is focused on understanding the genetic basis of coronary heart disease and its related quantitative phenotypes. The successful applicant will work on applying computational methods and performing large scale data analyses to identify novel common and rare variants which influence risk of cardiovascular and other cardiometabolic disease. In addition, they will use known genetic variants linked to these diseases and examine whether novel biomarkers and pathways casually influence risk.
PhD in Computer Science, Engineering, Math, Statistics, or a related quantitative discipline
EOE / Minorities / Females / Protected Veterans / Disabilities
Equal Opportunity Employer Minorities/Women/Protected Veterans/Disabled


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Neuroscientist

Date Posted:
3/17/2017

Regeneron

NY

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including oncology, rheumatoid arthritis, asthma, atopic dermatitis, pain, and infectious diseases.
Summary
We are seeking a talented scientist to join our Neuroscience research group. This individual should have an extensive background in mechanisms of neuronal pathology and neurodegeneration. Candidates with experience in neurotrophin biology are particularly encourage to apply. The successful candidate will be responsible for hands-on research studies designed to investigate novel targets and neuroprotection strategies for demyelinating disorders, motor neuron diseases, and peripheral neuropathies. The ideal candidate will be a motivated, self-starter and will have the opportunity to be a key part of an exciting new research focus.
Responsibilities
This candidate will work within a multidisciplinary group to design and execute a broad range of neuroscience experiments using both cell-based approaches and animal models. This candidate should have expertise with basic cell culture and molecular biology techniques (cloning, plasmid generation, etc.). The candidate should be flexible and open to learning cutting edge new techniques as needed. Also, this candidate should demonstrate the ability to teach and guide others using their areas of expertise. The candidate will be responsible for the reporting of results to a broad range of audiences and a high level of presentation and communication skills are required.
Requirements
This position requires a PhD with completion of a post-doctoral fellowship in a nationally recognized laboratory, 3+ years of post-PhD research experience. Required experience includes:?- Cell biology techniques.?- neuron biology (in the context of multiple sclerosis or other demyelinating diseases/neuropathy) or motor neuron disease (ALS).?- Must have working knowledge of experimental design and statistical analysis.??Level will be commensurate with experience
This position will require the individual to pass a physical before beginning employment.
This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron’s unwavering commitment to combining good science & good business.
To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid.
Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.


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Scientist Immunoassay development

Date Posted:
3/17/2017

Regeneron

NY

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including oncology, rheumatoid arthritis, asthma, atopic dermatitis, pain, and infectious diseases.
Summary
We are looking for a scientist with experience in immunoassay development and validation to work in the Assay Development group at Regeneron. The scientist will develop, validate and perform biomarker, PK and immunogenicity assays for biotherapeutics to support preclinical and clinical studies. The individual should have the ability to exercise independent judgment regarding interpretation and optimization data.
Responsibilities
Design, develop and validate immunoassays using ELISA, MSD or Gyros platforms for pharmacokinetic (PK), anti-drug antibodies (ADA) or biomarker detection in serum or plasma to support clinical or non-clinial bioanalysis
Analyze and summarize data
Troubleshoot assay problems
Reads and critically evaluates the literature in the bioanalytical field in order to develop novel approaches to develop and perform assays
Communicates effectively with supervisor and other managers within the Assay Development Group
Write development and validation reports and SOPs
Requirements
PhD in Biology, Immunology or a related field
1 year of biotech/pharma/CRO experience with biotherapeutics preferred
Experience in the development/validation of ELISAs and/or MSD assays for protein biopharmaceuticals in a regulated environment under GLPs
Experience with other assay platforms is a plus
Excellent organizational and communication skills, ability to multitask
Ability to maintain detailed lab notebook and keep a safe lab environment
Ability to effectively interact with colleagues in a team environment
Ability to independently plan, supervise and direct projects to completion, within required timelines, are essential
Supervisory experience is a plus


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Technical Writer/Editor II

Date Posted:
3/17/2017

BioRad

CA

Serve as editor and writer for the Life Science Group's Global Marketing and Communications Department
Partner with Marketing, Campaign, and Product Managers to develop concepts and content for advertising and marketing campaigns
Develop, write, and edit content marketing articles such as trends articles, customer stories, and content for bioradiations.com
Develop, write, and edit marketing materials such as brochures, fliers, technical/application notes, posters, video scripts
Ensure marketing and advertising collateral meet editorial style guidelines and are scientifically accurate
Collaborate in project teams with Art Directors, Graphic Designers, and Project Managers
What You Need For This Role
Master's degree in the life sciences (a must) and at least 3 years of experience writing and/or editing for a scientific audience or a PhD in the life sciences
Scientific knowledge -- Understands basic scientific concepts and laboratory techniques in molecular biology and biochemistry (chromatography, western blotting, etc.); communicates using accurate scientific language; understands what motivates researchers in the life sciences and how to write copy that resonates with them
Scientific writing/editing -- Is familiar with the structure and style of scientific articles; has written or contributed significantly to the writing of scientific articles; can provide feedback on logical progression of scientific ideas/arguements
Writing Skills -- Has strong writing skills and the ability to write a variety of materials (technical/application notes, advertising copy, brochure/flier copy, customer stories and trends articles, video scripts); must be able to adapt voice to match intent/purpose of each piece
Editorial Skills -- Has strong attention to detail and is familiar with Chicago Manual of Style or AMA Manual; is able to ensure internal consistency when editing lengthy documents; is able to consistently enforce style guidelines across all documents
Organizational Skills -- Is able to manage multiple projects simultaneously and effectively under tight deadlines
Must be able to uphold editorial style guidelines and provide guidance on writing style and strategy in a professional manner
Enjoys and is able to work effectively in a changing team environment
Candidates will be asked to take a writing and editing test for this position
What’s In It For You
Competitive pay and great benefits including medical, dental, vision, 401k and more
Opportunities for growth and training
Stability of a profitable 60+ year old company
Great work environment
About Bio-Rad
Bio-Rad is a global leader providing a broad array of clinical diagnostics and life science research products. With a team of more than 7,800 employees and a global network of operations serving our customers, we help people live longer, healthier lives.
Bio-Rad was founded over six decades ago and has continued to provide the healthcare industry with innovative and useful products that help life science researchers accelerate the discovery process and medical diagnostic labs obtain faster, better results.
EEO/AA Employer/Veterans/Disabled/Race/Ethnicity/Gender/Age
To all recruitment agencies: Bio-Rad does not accept agency resumes, unless the agency has been authorized by a Bio-Rad Staffing Representative. Please do not submit resumes unless authorized to do so. Bio-Rad will not pay for any fees related to unsolicited resumes.


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Bioinformatics Data Scientist

Date Posted:
3/17/2017

CyberCoders

PA

If you are a Bioinformatics Data Scientist with experience, please read on!
Located in the heart of Philadelphia, We are a well-funded, clinical stage, computational bio-sciences company with a focus on patient risk and cardiovascular monitoring. We are as passionate as ever about developing new technologies to detect and identify cardiovascular health as well as potential risk factors. We are seeking a seasoned Bioinformatics Data Scientist to join our computational research team!
What's In It for You
Hot Growth Startup Environment (Well-funded)
Leading technologies
Great Team and Notable Leadership
Vacation/PTO
Generous Benefits Package
What You Will Be Doing
Develop, deploy, and analyze database-driven computational analysis systems that carry out high-dimential data analysis and data mining solutions.
Develop and apply state-of-the-art computational analysis and interpretation approaches to leverage internal, public and partner datasets and empower data-driven program decision-making
Develop collaborations with external partners (Universities, Industry, other National Laboratories) to advance computational biology simulation efforts.
Integrate data across multiple experimental platforms and transfer knowledge from pre-clinical experiments to clinical trials.
Define and articulate best practices in software version control, test-development, and deployment
What You Need for this Position
At Least 4 Years Of Experience And Knowledge Of
A Master's Degree or PhD in Computer Science, Bioinformatics, Computational Biology or a related field preferred.
Expert knowledge in R, Python or shell scripting and is familiar with UNIX environments.
Excellence in Data mining and empirical modeling (Machine Learninga big plus)
Programming (R, Matlab, Python, Java)
Web application deployment (Apache, php, tomcat, Ruby/Rails, Grails)
Database technology (MySQL)
R/Bioconductor experience
Experience in Bioinformatics or Computational Biology (highly preferred)
So, if you are a Bioinformatics Data Scientist with experience, please apply today!
Email Your Resume In Word To
Looking forward to receiving your resume through our website and going over the position with you. Clicking apply is the best way to apply, but you may also:
Sam.Lee@CyberCoders.com
Please do NOT change the email subject line in any way. You must keep the JobID: linkedin : SL6-1341682 -- in the email subject line for your application to be considered.***
Sam Lee - Executive Recruiter - CyberCoders
Applicants must be authorized to work in the U.S.
CyberCoders, Inc is proud to be an Equal Opportunity Employer
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, protected veteran status, or any other characteristic protected by law.
Your Right to Work - In compliance with federal law, all persons hired will be required to verify identity and eligibility to work in the United States and to complete the required employment eligibility verification document form upon hire.
CyberCoders will consider for Employment in the City of Los Angeles qualified Applicants with Criminal Histories in a manner consistent with the requirements of the Los Angeles Fair Chance Initiative for Hiring (Ban the Box) Ordinance.


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Scientific Manager - Immunology

Date Posted:
3/17/2017

MD Anderson Cancer Center

TX

The goal of MDA department of Immunology is to perform multidisciplinary research and educational activities in basic and cancer immunology.

The salary range is min $ 82,500 mid $ 123,600 max $ 164,800.

1. Key Functions:

* Contributes to the overall management of the Immunotherapy Platform across MD Anderson Departments and multi-institutional consortium networks. Establishes, develops, and fosters collaborative relationships with industry and academic leaders to assure advancement of organizational and platform goals. Ensures systems, policies and procedures are in place to facilitate successful collaborations.

* Ensures that strategic and tactical plans for the ongoing activities of the platform are developed and executed efficiently. Provides scientific input for all aspects of the platform including protocol management, budgets, contracts, and specimen procurement.
* Reviews, evaluates, interprets, and integrates medical records, patient data, patient specimens, and/or test results and provides correlation with the different laboratory analyses, including but not limited to flow cytometry, molecular pathology, Nanostring technology, murine/pre-clinical studies, etc..
* Exhibits understanding of the processes of clinical research and pharmaceutical product development/approval.
* Attends and may lead the face-to-face and/or teleconference IMT meetings with alliance partners and academic collaborators: able to give data presentations and facilitate discussions regarding the advancement of science and research.
* Assigns/manages tasks to ensure platform deadlines and milestones are met. Develops reports, Gantt charts, and other tracking tools to ensure ongoing updates are available to Immunotherapy Platform staff.
* Works closely with the department administrator, faculty, research management team, and informatics staff to address issues and coordinate the development and implementation of operational solutions related to research protocols and electronic research applications.
* Writes and prepares various reports. May assist in the writing and planning of research grants.
* Other duties as assigned.

EDUCATION:

Required: Bachelor's degree in one of the basic sciences.
Preferred: PhD in one the basic sciences.

EXPERIENCE:

Required: Seven years relevant research experience to include two years in a supervisory/managerial capacity. With preferred Masters degree, five years of required experience to include two years in a supervisory/managerial capacity and with preferred PhD, three years of required experience to include two years in a supervisory/managerial capacity.


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Scientist I

Date Posted:
3/17/2017

Bristol Meyers Squibb

NJ

In the Molecular and Analytical Development group of BMS, we are a world-class Mass Spectrometry and Biophysics Center of Excellence to support the development of life-saving medicines in immuno-oncology and other therapeutic areas. We specialize in biologics development using state of the art biophysical methods to decipher the structural complexities of biological molecules. We foster an innovative and collaborative environment that values and recognizes diversity of contributions, and pushing the limits of technology for analyzing monoclonal antibodies, fusion proteins, and other novel scaffolds progressing in clinical trials for unmet medical needs.
The Molecular and Analytical Development group is seeking a highly motivated and creative Biophysical Scientist to analyze structure, stability, and post-translational modifications of proteins to support development of biopharmaceuticals, and be part of the leadership position of BMS in Immuno-Oncology. This individual is also expected to push the limits of advanced biophysical techniques for characterization of therapeutic monoclonal antibodies, antibody drug conjugates, fusion proteins, and other protein modalities.
These Techniques Include, But Are Not Limited To
spectroscopy (FTIR, Raman, CD, fluorescence, UV/VIS)
analytical ultracentrifugation
microscopy (FTIR, Raman, AFM)
flow-based protein particulate enumeration and imaging (HIAC, MFI, FlowCam)
static and dynamic light scattering
calorimetry (DSC, ITC)
chromatography (SEC, IEX, RP)
capillary electrophoresis (iCIEF, SDS-CGE)
Additional responsibilities include defining critical quality attributes and understanding protein post-translational modifications including degradation pathways in in-vitro systems. He/she is also expected to publish novel findings in journals and present scientific data at internal and external conferences.
Responsibilities will also include matrix team leadership. The individual will work independently and in collaboration with colleagues within analytical and across various functional areas to support programs from clinical development through registrational studies.
An ideal candidate would have experience with therapeutic proteins including mAb, bispecific antibodies, fusion proteins, antibody drug conjugates and other derivatized proteins, and their structure-function relationships. Proven track record of independent research capability and problem solving ability is required for this position.
This individual will be required to interpret and present scientific data, contribute to IND, IMPD, BLA, and other regulatory filings, write technical reports and represent the department in matrix team environment when needed. Attention to detail and be able to work in a highly collaborative environment under tight timelines are required attributes.
We look for scientists who are truly inspired by our mission and who would share our passion for collaborative and entrepreneurial work culture. Because we know that employees are key to our success in bringing novel cancer medicines to patients, we are committed to providing employees with benefits that allow them to bring their best.
Bristol-Myers Squibb is an equal opportunity employer - Vet/Disability
Job Function
Analytical Chem - Mfg Ops
Primary Location
NA-US-NJ-Pennington
Organization
GMS - BDO
A PhD in biophysics, biochemistry, physical chemistry, chemical engineering, pharmaceutical science or a related scientific discipline with 0-3 years of relevant experience in biopharmaceutical/biotechnology, or a Masters with a minimum of 5 years of relevant experience is required.
Knowledge of protein chemistry, structure, function, and folding are essential.
The individual should possess demonstrated skills and proficiency in biophysical techniques including operation, maintenance and troubleshooting of instruments.
Familiarity with protein higher order structure analysis, protein particulate techniques such as flow imaging as well as microscopy is a plus.
The individual will interface and collaborate with multi-disciplinary teams in a high paced analytical laboratory environment.
Excellent communication, interpersonal and organizational skills are essential.
Attention to detail and be able to work in a highly collaborative environment under tight timelines is required.
Seniority Level
Not Applicable

Industry
Biotechnology Logistics and Supply Chain Pharmaceuticals
Employment Type
Full-time

Job Functions
Research Analyst Information Technology


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Chief Scientist Lab Diagnostics and Monitoring HIV

Date Posted:
3/15/2017

General Dynamics Land System USAMRIID

MD

This Chief Scientist position is in support of the Department of Laboratory Diagnostics and Monitoring, Military HIV Research program and requires a senior Doctoral level Scientist to provide scientific leadership, and management skills in the provision of the following services: Leadership of research activities in the HIV Lab Diagnostics and Monitoring Program to include development of assays and validation and adaptation of commercial assays for prevalent and emerging infectious disease pathogens. Oversight of the design, development and validation of reagants, test kits, platforms and laboratory developed tests for use in prevalent and emerging infectious pathogen screening, confirmation, and monitoring. Authorship of specialized scientific and technical reports Design and prepare research protocols in accordance with relevant regulatory, laboratory and ethical policies Preparation of presentations for national and international scientific forums

 

EducationDoctoral degree (PhD, ScD) in relevant scientific discipline.Qualifications10-15 years of related experience in scientific research, specifically in diagnostics, antivirals, and/or vaccines Demonstrated knowledge and experience with cooperative research and development agreements (CRADAs) and material transfer agreements (MTAs) Significant record of publication in peer reviewed literature

 

As a trusted systems integrator for more than 50 years, General Dynamics Information Technology provides information technology (IT), systems engineering, professional services and simulation and training to customers in the defense, federal civilian government, health, homeland security, intelligence, state and local government and commercial sectors.With approximately 32,000 professionals worldwide, the company delivers IT enterprise solutions, manages large-scale, mission-critical IT programs and provides mission support services.GDIT is an Equal Opportunity/Affirmative Action Employer - Minorities/Females/Protected Veterans/Individuals with Disabilities.

Seniority Level

Director

Industry

  • Defense & Space

Employment Type

Full-time

Job Functions

  • Engineering
  • Information Technology
 

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Sceintist I

Date Posted:
3/15/2017

Leidos

MD

The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish National Cancer Institute (NCI) research objectives. The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community. A major focus of the CRTP is the NCI RAS Initiative with the goal to discover new therapeutic interventions against RAS-driven cancers.

 

Responsibilities

 

JOB DESCRIPTION/BASIC FUNCTION

 

  • Will work in support of the FNL/NCI RAS Initiative with a highly collaborative multidisciplinary team of chemists, biochemists, structural and cell biologists, to develop and optimize agents for use as RAS inhibitors
  • Analyze high-throughput screening data to identify preliminary structure-activity relationships (SAR)
  • Provide synthetic support during hit validation studies
  • Conduct hit-to-lead chemistry efforts around those targets/screens that yield advanceable hits

     

Basic Qualifications

 

Qualifications:

 

To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:

 

  • PhD in a field related to medicinal chemistry, or in a related discipline from an accredited college or university according to the Council for Higher Education Accreditation (CHEA) appropriate to biomedical research, or eight (8) years of experience in lieu of degree
  • Foreign degrees must be evaluated for U.S. equivalency
  • Expertise in the design, synthesis, and characterization of pharmaceutically relevant small molecules
  • Experience with modern analytical technologies including: LCMS, NMR (1H, 13C, 2D techniques), HPLC, IR, Flash chromatography
  • Experience with the design and preparation of small-molecule compound libraries
  • Must be highly collaborative, self-motivated and team oriented
  • Must have excellent oral and written communication skills
  • Ability to efficiently manage workload over multiple projects
  • Must be able to obtain and maintain a Security Clearance

     

Preferred Qualifications

 

Candidates with these desired skills will be given preferential consideration:

 

  • Expertise in mass spectrometry (quantitative MS, MS/MS, MALDI-TOF, proteomics, and metabolomics)
  • Strong publication record

     

Leidos Overview

 

Leidos is a global science and technology solutions leader working to solve the world’s toughest challenges in the defense, intelligence, homeland security, civil, and health markets. The company’s 33,000 employees support vital missions for government and commercial customers. Headquartered in Reston, Virginia, Leidos reported pro forma annual revenues of approximately $10 billion for the fiscal year ended January 1, 2016 after giving effect to the recently completed combination of Leidos with Lockheed Martin's Information Systems & Global Solutions business (IS&GS). For more information, visit www.Leidos.com. The company’s diverse employees support vital missions for government and commercial customers. Qualified women, minorities, individuals with disabilities and protected veterans are encouraged to apply. Leidos is an Equal Opportunity Employer. Scientist / Research & Development


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Scientific Program Manager, Policy and Regulatory Lead Gene Drive Research

Date Posted:
3/15/2017

Foundation for NIH

MD

Position Description:
This is a professional scientific and administrative management position for an individual with experience and knowledge of international regulatory and policy issues relevant to biotechnology interventions aimed at improving public health. The Scientific Program Manager will participate in the strategic implementation of a portfolio of activities to support the successful introduction of gene drive technologies, with a focus on mosquitoes modified with driving transgenes as tools to control malaria transmission in Africa. The incumbent will provide administrative and regulatory advice and guidance to individuals and organizations (national and multi-national) with various different roles, responsibilities and interests in gene drive research and its potential deployment. This Scientific Program Manager will be responsible for regulatory and policy leadership within the team environment.

Essential Functions:

  • Facilitates the establishment and promotion of best practices for safe, ethical, and effective testing of a new and evolving technology. This includes, but is not limited to, planning and coordinating activities aimed at creating a uniform regulatory and policy environment for gene drive interventions aimed at malaria control, such as overseeing independent ecological risk assessments for interventions proposed for field testing, developing regulatory trainings, supporting regulatory-related capacity building for field testing at African sites and interacting with national and international policy-makers.
  • Collaborates with representatives of funding organizations, academic and other research organizations, regulatory, government and health-related agencies, and others to improve awareness and develop coordination of regulatory and related policy activities for gene drive technologies.
  • Interacts with individuals and organizations influential in decision-making on the introduction of new biotechnology products at the national and international level.
  • Provides technical and organizational leadership for regular convenings to initiate, improve and promote regulatory harmonization across sub-Saharan Africa.
  • Represents FNIH at relevant scientific, regulatory and policy meetings.
  • Assists, within a team environment, in designing new activities; creates timelines and resource plans; participates in relevant negotiations; and develops reports to funders and for distribution/publication.
  • Contributes to planning for and development of an anticipated, separately funded and sustainable new collaborative enterprise that will play a leadership role in long-term support for the development and implementation of gene drive approaches for malaria control.

The Scientific Program Manager will possess intellectual and scientific skills and knowledge as well as the organizational and administrative abilities to work effectively with a variety of internal and external partners. Recognizing the evolving approaches to and outcomes of research and regulations requirements, and ever-changing attitudes towards gene drive technology, s/he must be attentive to the rapid pace of technical advances, to proposed changes in policies and regulations and to community and public perception of the technology.
International travel to perform the functions of the Scientific Program Manager is estimated at 10-25% per year.
The incumbent will report to the Director of the Science Division, FNIH.

Qualification:
The Scientific Program Manager should have a demonstrated ability to:

  • Provide regulatory advice and guidance on gene drive technology to multi-disciplinary, multi-organizational research efforts.
  • Work collaboratively and productively with a wide range of partners, such as research and other technical organizations, regulatory and other government agencies, funding entities, and advocacy organizations both in the U.S. and internationally.
  • Identify, work with and influence individuals at appropriate organizations necessary to achieve the goals of a program.
  • Effectively communicate about complex scientific technology, and the scientific, ethical, regulatory and public considerations for conducting clinical/field trials.
  • Work successfully within a team environment.
  • Manage and meet timelines and milestones.

A doctoral degree in a biological science and demonstrated knowledge of and experience with regulatory science and/or science policy is required.
Preference will be given to candidates with experience in the following areas:

  • Safety and efficacy testing of new biotechnology products.
  • Techniques of synthetic biology.
  • International programs/projects, particularly in Africa.

To Apply:
Please send cover letter and resume to resumes@fnih.org referencing SciTechWS. Please note that only those applications including both a cover letter and resume will be considered.
Cover letter will address the following:

  • Key attributes that denote the applicant's ability to perform the essential functions.
  • Why the applicant fulfills the job qualifications.
  • Why the applicant is interested in working at FNIH in this position.

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Scientific Program Manager, Technical Lead Gene Drive Research

Date Posted:
3/15/2017

Foundation for NIH

MD

Position Description:
This is a professional scientific and administrative management position for an individual with experience and knowledge of the application of genetic engineering and synthetic biology technology for creating products to improve public health. The Scientific Program Manager will participate in the strategic implementation of a portfolio of activities to support the successful introduction of gene drive technologies, with a focus on mosquitoes modified with driving transgenes as tools to control malaria transmission in Africa. The incumbent will provide administrative and technical advice and guidance to individuals and organizations (national and multi-national) with various different roles, responsibilities and interests in gene drive research and its potential deployment. This Scientific Program Manager will be responsible for technical leadership for the FNIH effort.

Essential Functions:

  • Facilitates the establishment and promotion of best practices for safe, ethical, and effective testing of a new and evolving technology. This includes, but is not limited to, planning and coordinating activities aimed at creating a uniform research and development environment for gene drive interventions aimed at malaria control, such as achieving agreement on the necessary product characteristics to contribute to malaria elimination, developing standards for testing of gene drive candidates, and supporting relevant capacity building for field testing at African sites.
  • Collaborates with representatives of funding organizations, academic and other research organizations, communications/advocacy groups, and others to maintain awareness and coordination of a broad range of gene drive research and related activities.
  • Provides technical and organizational leadership for various convenings of gene drive sponsors, supporters and researchers to facilitate collaboration in areas of mutual interest.
  • Represents FNIH at relevant scientific and policy meetings
  • Assists, within a team environment, in designing new projects; creates timelines and resource plans for proposed activities; participates in relevant negotiations; and develops reports to funders and for distribution/publication.
  • Contributes to planning and development of an anticipated, separately funded and sustainable new collaborative enterprise that will play a leadership role in long-term support for the development and implementation of gene drive approaches for malaria control.

The Scientific Program Manager will possess intellectual and scientific skills and knowledge as well as the organizational and administrative abilities to work effectively with a variety of internal and external partners. Recognizing the evolving approaches to and outcomes of research and regulations requirements, and ever-changing attitudes towards gene drive
technology, s/he must be attentive to the rapid pace of technical advances, to proposed changes in policies and regulations and to community and public perception of the technology.
International travel to perform the functions of the Scientific Program Manager is estimated at 10-25% per year.
The incumbent will report to the Director of the Science Division, FNIH.

Qualifications:
The Scientific Program Manager should have a demonstrated ability to:

  • Provide technical advice and guidance to multi-disciplinary, multi-organizational research efforts.
  • Work collaboratively and productively with a wide range of partners, such as research and other technical organizations, regulatory and government agencies, funding entities, and advocacy organizations both in the U.S. and internationally.
  • Identify, work with and influence individuals at appropriate organizations necessary to achieve the goals of a program.
  • Effectively communicate about complex scientific technology, and the scientific, ethical and public considerations for conducting clinical/field trials.
  • Work successfully within a team environment.
  • Manage and meet timelines and milestones.

A doctoral degree with at least three years of relevant research experience (e.g. molecular entomology, field entomology, malaria, product development for mosquito control) and three years of science administration or equivalent experience is required.
Preference will be given to candidates with experience in the following areas:

  • Techniques of genetic engineering and synthetic biology, especially gene drive technology.
  • Basic and/or applied research to develop malaria control tools.
  • International programs/projects, particularly in Africa.
  • International standards for research on genetically modified organisms.

To Apply:
Please send cover letter and resume to resumes@fnih.org referencing SciTechWS. Please note that only those applications including both a cover letter and resume will be considered.
Cover letter will address the following:

  • Key attributes that denote the applicant's ability to perform the essential functions.
  • Why the applicant fulfills the job qualifications.
  • Why the applicant is interested in working at FNIH in this position.
  • Any unique qualities or experience the applicant would bring to the position.

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Assistant Director The Learning Program STEM Transformation

Date Posted:
3/15/2017

Florida International University

FL

Position Description:
The STEM Transformation Institute at Florida International University (FIU) is seeking applications for an Assistant Director of the Learning Assistant (LA) Program. The Learning Assistant (LA) Program is a highly innovative program that fosters implementation of evidence-based classroom practices, engages faculty in course transformation, develops undergraduate students to become facilitators of learning in the classroom and studies the impact of transformations. The Assistant Director (AD) will be involved in all aspects of the LA Program, working closely with the program leaders, undergraduate students, faculty and university administrators. Primary responsibilities include facilitating adoption of the LA model with new faculty and emergent disciplines, including working with faculty and departments to redesign courses to enable best practices in LA-supported courses. Other responsibilities include coordination with other faculty development initiatives and FIU's administration and possibly management of staff. Opportunities for teaching/advising/research may exist. This is a full time, 12-month position, starting as soon as the position filled. Position requires limited travel, primarily to disseminate outcomes of the program.
FIU's STEM Transformation Institute is dedicated to advancing research and educational change that promotes evidence-based instructional practices, utilizing FIU as a laboratory for the future of STEM, as over 75% of FIU's 54,000 students come from traditionally underrepresented groups. The Institute currently hosts 11 discipline-based education research faculty in six STEM departments and 14 staff / postdoctoral researchers that carry out multidisciplinary collaborative work across the Colleges of Arts, Sciences & Education and Engineering & Computing. Hallmark programs include a Learning Assistant (LA) program that impacts well over 13,000 student enrollments in 10 STEM disciplines each semester; Modeling Instruction at the high school and college levels; and multiple HHMI- and NSF-funded research projects. For more information on programs and research at the STEM Transformation Institute: stem.fiu.edu; FIULearn.fiu.edu; FIUteach.fiu.edu. FIU is the public research university in Miami, Florida and is the only majority minority Carnegie R1 research university in the nation.

Qualifications:

  • An earned master or doctorate in science, mathematics, engineering or science/mathematics/engineering education;
  • Minimum 3-years academic experience in teaching and/or in directing academic support experiences;
  • Very strong oral and written communication skills.

Additionally, preference will be given to candidates who demonstrate:

  • Knowledge of recent advances in science, mathematics and/or engineering teaching and learning and/or discipline-based education research (DBER);
  • Experience in supporting course transformation and faculty development;
  • Teaching, advising, and/or administration in higher education;
  • Experience working in collaborative environments.

To Apply:
Qualified candidates are encouraged to attach a cover letter, curriculum vitae and list of three references (with contact information) in a single pdf file and send it to stem@fiu.edu. Note that at least three references may be contacted upon review as determined by the search committee. To receive full consideration, applications and required materials should be received by March 20th, 2017. Applications will be reviewed continually until position is filled. For more information and inquiries emailstem@fiu.edu.


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Future Leaders Program

Date Posted:
3/15/2017

GSK

MD

Program Description:
The Future Leaders Program suits graduates who want a career with real purpose. It's an accelerated development program that equips graduates with the knowledge, skills and attributes to move quickly into senior positions at GSK. Participants benefit from a rich variety of structured training, individual mentoring, and opportunities to experience different aspects of the business. From the start, our challenging rotations will help you deliver the standards of excellence that we'd expect from a future leader.

During the two-year Future Leaders Program you will gain a broad and insightful experience of GSK's vaccines R&D business and the groundbreaking science shaping the organization. The program involves four rotations within different R&D departments, including one abroad. Rotations are chosen to give you the skills, experience and perspective required to succeed in the target leadership position you will step into at the end of the program. Typically, the rotations include time in a hands-on project management role helping to direct the development of a new vaccine, and an external facing position where you will have direct customer contact with healthcare professionals and patients. You will also have the opportunity to see science in action in our labs and learn about the risk and compliance side of vaccine production.
The programme follows the 70:20:10 learning principle: 70% of your learning takes place on the job during your rotations, 20% is the support you'll receive from a senior leader who will be your mentor throughout the program, and the remaining 10% comprises formal leadership training sessions.

What do I need to succeed?

Our Future Leaders need ambition, commercial awareness and a self-motivated, proactive approach. We're looking for clear, effective communicators who can quickly build a rapport with a wide range of people. It's also important that you can adapt to change and keep focused when the pressure is on. While you have the drive and confidence to trust your own judgement, you're a real team player who actively collaborates with others. In addition, you'll need an analytical mind, a talent for multi-tasking and the ability to influence others.

We are looking for candidates who can make outstanding long-term contributions to our organization.
The ideal candidates are driven, curious and can easily build relationships with others; easily adapt to different situations and environments, learn fast, are proactive, result-oriented and driven by challenges and, most importantly, share GSK Values and Expectations.

The benefits of working at GSK Vaccines include innovative projects, passionate people and a truly global business atmosphere. At GSK we provide a supportive working environment, and a range of development challenges and opportunities. We also offer competitive benefits and compensation packages designed to attract and to retain the very best.

Basic Qualifications:

  • Completion of MS, PhD degree in a scientific discipline (ie: biochemistry, biology, microbiology, immunology and pharmacology) by June 2017
  • Possess no more than 2 years of professional experience in the related pharmaceutical/biotechnology industries
  • Masters, PhD: maximum 2 years professional experience after your graduation
  • Post-Doc fellows: maximum 2 years after completion of your PhD
  • Must be eligible to work in the US at the time of, and for the duration of employment. Employees will be required to furnish evidence of US work authorization. Applicant must NOT require future sponsorship for an employment visa status.
  • Willingness to work internationally is required. Ability to be mobile and spend up to 12 months abroad during the program is required.
  • 3.0 GPA or above

Preferred Qualifications:

  • Candidate with a professional degree in Medicine (MD/PhD), Public Health or Business (MBA/PhD)
  • Previous research experience in either the industry or university setting
  • Previous work experience in related pharmaceutical/biotechnology industries, especially with Vaccine development
  • Candidate with working knowledge of French

To Apply:
For more information and to apply online, please click here.


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Scientist I/II Translational

Date Posted:
3/11/2017

Biogen

MA

Scientsit I/II, Translational Sciences
Job Description The Global Biomarker Discovery and Development groups seeking multiple highly motivated scientists to join a dynamic team engaged in the discovery and progression of novel biomarkers for autoimmune and neuroinflammation disease areas. Responsibilities include leading scientific research to identify, evaluate, and characterize relevant fluid biomarkers that will provide useful pharmacodynamic and efficacy endpoints in preclinical and clinical settings. The successful candidate will be capable of multitasking, setting goals, priorities, and planning timelines. Effective communication and collaboration are crucial. Ability to think critically and a commitment to learning are essential.
*Responsibilities:

• Provide strategic input into the identification and validation of novel biomarkers to assist in program progression.

• Develop in vitro assays and technologies to evaluate efficacy, PK/PD relationship, and novel biomarkers that characterize drug candidates for potential therapeutic effects.

• Recognize and troubleshoot data anomalies to ensure high data quality.

• Liaise with cross-functional project teams as the subject matter expert.

• Prepare, review and deliver scientific presentations for internal/external use.

• Learn new techniques and approaches as needed to tackle relevant questions.

• Commitment to help the team achieve deliverables and meet aggressive timelines.

*LI-RD2
Location Cambridge, MA, US
Job Category Research
Requisition Number 30172BR
Qualifications 1. Track record of developing flow cytometry and cell-based assays that interrogate immune function.
2. Familiarity with ligand binding and cell-based assays, utilizing a variety of technology platforms.
3. Excellent assay troubleshooting skills and the ability to identify and evaluate cutting edge assay technologies.
4. Experience in cellular and biochemical science such as standard molecular biology and protein biochemistry techniques (e.g. real-time PCR, DNA cloning, protein purification, Western blotting, immunoprecipitation, enzymatic assays).
5. Background in immunology or neuro-immunology, including experience working in disease areas such as multiple sclerosis, lupus, stroke, or other inflammatory diseases.
6. Hands on experience in the development and validation of biomarker assays in the preclinical and clinical setting is considered a plus.
7. Strong leadership skills and the ability to work independently or with minimal supervision in managing multiple projects and priorities.
8. Ability to collaborate and work in a matrixed environment.
9. Demonstrated record of productivity including providing support activities for multiple research projects and contributing author on peer reviewed publications.
Education PhD with at least 2-5 years postdoctoral research in either an academic or industry setting.
About Biogen Biogen (NASDAQ: BIIB) is a biotechnology leader that discovers, develops and delivers innovative therapies for the treatment of neurodegenerative and rare diseases. Patients worldwide benefit every day from our medicines for multiple sclerosis (MS) and hemophilia.

Founded in 1978, Biogen is one of the world’s oldest independent biotechnology companies. Our development pipeline is focused on areas of high unmet medical need, as we pursue new therapies for patients suffering from diseases with few or no treatment options. These include programs for Alzheimer’s Disease, amyotrophic lateral sclerosis (ALS), Parkinson’s disease, spinal muscular atrophy and neuropathic pain amongst others.

With more than 7,000 people worldwide, Biogen is truly a global organization. We are headquartered in Cambridge, Massachusetts, which is home to our research operations. Our international operations are based in Zug, Switzerland and we have world-class manufacturing facilities in North Carolina and Denmark. We offer therapies globally through direct affiliate presence in 30 countries and a network of distribution partners in over 50 additional countries.

All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.

Please be advised that all legitimate correspondence from a Biogen employee will come from "@biogen.com" email accounts.


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Scientist I Genetics and Genomics

Date Posted:
3/11/2017

Biogen

MA

Computational Biology and Genomics (CBG) is a center of excellence platform line in the Research and Early Development organization at Biogen. The group is responsible for providing genetics and genomics expertise to the R and D organization and specifically applies genetic and genomic discoveries to support Biogen’s drug discovery research clinical development programs. This position will report into the NGS and Genetic Technologies Hub in the CBG organization which provides laboratory support and delivers data to support human disease genetics research projects. We are looking for a PhD level scientist to focus on studying genetics of gene regulation in multiple diseases of interest, and help evaluate, develop and implement novel NGS, RNA and/or DNA technologies to support such studies and other CBG strategic imperatives. The successful candidate will be expected to work closely with Biogen discovery, clinical, and computational scientists to deliver high content genetic and genomic data to impact drug discovery and development activities at Biogen. This individual will employ creative molecular solutions to advance our understanding of the molecular basis of the complex diseases we seek to treat, supporting the discovery of novel potential drug targets, biomarkers, and provide information on drug mechanism of action. As a subject matter expert on specific genomic technologies this role will interface with project teams to provide guidance on application of technologies, experimental design and data interpretation and keep Biogen at the cutting edge of genomic sciences.
Responsibilities

• Develop a program of research in the area of the genetics of gene regulation that will support Biogen’s drug discovery efforts in neurology and rare genetic disease.

• Identify, evaluate and develop novel genomic technologies to advance drug discovery and development activities

• Partner with TA scientists in Discovery Research and Clinical Development team leaders to identify key questions and priorities that novel genetic and genomic technologies can impact

• Deliver high content molecular data for key research projects in CBG

• Identify opportunities for external collaborations that supplement internal CBG resources and ensure genetic and genomic biomarker research is at the cutting edge


*LI-RD2
Location Cambridge, MA, US
Job Category Research
Requisition Number 30157BR
Qualifications PhD in genetics, genomics or a related discipline. Post-doctoral experience is not essential.
• Keen interest in the application of new genetic and genomic technology and deep understanding of human genetics.
• Expertise in NGS technologies and hands on experience developing creative solutions to address biological questions.
• Experience of the evaluation of different genomic technologies.
• Strong collaboration, organizational and communication skills and an ability to work well in a team setting are required.
• The candidate should have be able to work independently have a strong ability to learn and adapt to work on new tasks and projects that he/she may not have worked on previously.
Education Ph.D in Genetics, Genomics or a related discipline

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Scientist Molecular Biology

Date Posted:
3/11/2017

Prothena

CA

The Molecular Biology Research group is seeking a motivated Scientist to join an exciting research team focused on the discovery and development of novel therapeutics for neurodegenerative, inflammatory, and misfolded protein diseases. The qualified candidate must be scientifically driven and will have the opportunity to work in a multi-disciplinary team developing first-in-class antibody therapeutics. The scientist will design, undertake experiments and report preclinical molecular biology study results.

 

Responsibilities:

  • Engineering and expression of monoclonal antibodies and proteins
  • Humanization, optimization, and reformatting of antibodies, including antibody homology modeling and site-directed mutagenesis
  • Molecular cloning of antibodies and protein into expression vectors
  • Antibody/protein expression in bacterial and mammalian cell cultures using shake-flasks and Wave Bioreactors
  • Characterize humanized antibodies using a variety of bioinformatics and biochemical techniques (PAGE & Western blots, ELISA, PCR & qPCR, Fortebio and Biacore etc.)
  • Work closely with other teams to evaluate humanized antibodies in a variety of in vitro and in vivo models
  • Supervise technical staff and facilitate smooth functioning of the lab
  • Maintain accurate and up-to-date records, present results at company meetings and to collaborators, support patent filings and train others in the use of the technology
  • Communicate data internally and in external meetings in oral and written formats
 

Qualifications:

Education and/or Experience:

  • The candidate must have a D. in Biological Science (Molecular Biology, Cell biology, Immunology, Protein Chemistry, Structural Biology) or a related field with at least 5 years of academic and/or industry work experience within antibody discovery

Competencies and Attributes:

  • Strong track record and hands-on experience in contemporary molecular biology techniques, antibody engineering and bioinformatics are required
  • Strong hands-on experience with basic cell biology, mammalian & bacterial protein expression and protein assay techniques is required
  • The ability to manage multiple projects efficiently, to communicate clearly & effectively and work within collaborative environment is essential
  • Well-documented, strong scientific background within molecular biology, antibody research documented in publications in highly regarded journals and/or intellectual property generation
  • Experience in small-scale bioreactor operation for antibody production is a plus
  • Previous experience with affinity screening and binding kinetics assays using label-free (ForteBio/Octate) techniques is a plus
  • Achieve company objectives in accord with the Prothena core cultural values of courageous, creative, selfless and humor
 
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Scientist Product Characterization

Date Posted:
3/11/2017

Teva

PA

Responsibilities

Responsible for assay development as a core competency for biologics development due to the complexity of large proteins.  Maintain a broad understanding of current analytical technologies for biologics development in a regulated environment.  Progress molecules to commercialization.  Manage product and method characterization activities.  Responsible for the development of analytical methods for protein drug substances, preparation of method descriptions and reports, and characterization of proteins by various analytical techniques.  Work as a technical subject-matter expert to support troubleshooting.  Guide or oversee junior associates or scientists to design and execute studies.  Contribute to regulatory filings, CGMP regulations compliance, and responses to Health Authority questions.  Evaluate new and emerging analytical technologies.  Author technical reports and procedures.  Conduct High Performance Liquid Chromatography (HPLC), mass spectrometry, and peptide mapping.

 

Qualifications

Requirements:  This position requires a Ph.D. degree or foreign academic equivalent in Biochemistry, Molecular Biology, or a related field.  Plus 2 years of experience in the job offered or 2 years in a related occupation including Scientist, Researcher, or related biopharmaceutical experience.  Will accept a Master’s degree plus 5 years of experience in lieu of the required education and experience.  Position requires at least 1 year of experience with characterization of proteins, HPLC, and mass spectrometry.  Will accept any suitable combination of education, training, or experience as per the requirements cited herein.  40hrs/week, 8:00AM – 5:00PM.

 

Application Instructions:  To apply, please E-MAIL resume, ensuring to indicate the position reference code for which you are applying (Ref# SPC228EG) to Diane Barnett, Director-Global atDiane.Barnett@tevapharm.com.

 
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Scientist I Immunology

Date Posted:
3/11/2017

Celgene

MA

Summary:

We are currently seeking an innovative scientist with expertise in immunology, inflammation, and autoimmune diseases to join our Immunology & Inflammation Discovery Biology group in Cambridge, MA.  He/she will be expected to contribute ideas for new drug discovery projects, establish state-of-the-art cellular assays and in vivo and ex vivo models to validate therapeutic targets, demonstrate efficacy of lead compounds, perform detailed mechanism of action studies, run a drug discovery program and provide translational biology support to programs as they enter and move through clinical development. 

 

Qualifications and Responsibilities:

  •  Research experience in multiple inflammatory & autoimmune diseases and/or cancer immunotherapy is required.
    Extensive hands-on experience in isolation, culture, and characterization of primary immune cells from human and animal tissues is required.
    Extensive cell-based and biochemical assay development experience with a variety of readout technologies including flow cytometry, ELISA, and immunofluorescence is required. 
    Experience with a variety of in-vivo and ex-vivo models of inflammation, autoimmune and cancer immunotherapy is strongly preferred.  
    The successful candidate will have outstanding experimental design, troubleshooting, and data analysis skills. Experience with laboratory automation and/or bioinformatics would be a plus.
    Excellent communication, presentation, collaboration and organizational skills are required. 
    Able to distill complex issues and clearly articulate innovative solutions
    Ability to demonstrate effectiveness and growth in a fast-paced and dynamic       team environment.
    Some prior experience managing research associates is a plus.

Excellent record of performance and scientific accomplishments as demonstrated by impactful contributions to the scientific community, pipeline contributions, peer reviewed publications and patent applications.
Clear evidence of sustained independent thought and creativity in developing and implementing advanced technology and ideas for new drug discovery projects. 
Individuals with strong leadership, communication skills, and with experience in participating in and/or leading multi-disciplinary project teams are encouraged to apply.
 

 

 

#LI-JT1 - PR

BIO-US PRIORITY


Qualifications

Job Requirements:

This position requires a Ph.D. with 2+ years of post-doctoral experience, or MS with a minimum of 8+ years experience in immunology or a related field in an academic and/or industry setting.  The ideal candidate will have a reputation as a scientific innovator and collaborator, and have an outstanding track record of success.  

 

Celgene is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.

 

Celgene complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Celgene in the U.S.


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Research Scientist Computational in Spain

Date Posted:
3/11/2017

Celgene

INT

Multinational biopharmaceutical company Celgene, world leader in developing new treatments for cancer and inflammatory diseases, has established the Celgene Institute for Translational Research Europe (CITRE®) in Seville, Spain. CITRE is the company’s first dedicated R&D site outside the USA and provides a bridge between Celgene R&D and the European research community.

 

CITRE was founded in 2010, and laboratory research activities began in June 2011. The Institute now houses a team of highly qualified scientific research and administrative staff drawn from Spain and other European member states. The Institute is located in the Cartuja ‘93 Science and Technology Park and its activities focus on Translational Research into new treatments for cancer and other rare and complex diseases.

 

Scientific activities at CITRE comprise three main departments: The Human Diseased Tissue Laboratory (HDTL), the Computational Biology research group, and the Clinical Trials Unit. Onsite facilities include extensive cell culture, flow cytometry, microscopy, genomics, immunohistochemistry, and state-of-the-art computational analysis infrastructure for biomarker discovery and patient stratification.

 

The three groups are inter-linked by the CITRE tissue Biobank, which receives patient tissue samples, obtained from multi-centre Celgene trials managed by the CITRE Clinical Trials Unit in Spain and across Europe, to provide the basis for inter-disciplinary research into biomarker detection, patient selection criteria, and compound mechanisms of action.

 

Together, these components form a Translational Research centre which coordinates and conducts Celgene medical research in Europe, and enables rapid and effective transfer of new developments and discoveries at Celgene to EU patients. Furthermore, CITRE provides a focal point in Europe for collaborative translational research into cancer and inflammatory diseases, with a mission to rapidly deliver new Celgene compounds to the clinic.


Qualifications

 Requirements

 

  • PhD in computational biology / bioinformatics, statistics, computer science or related fields, with a firm grasp of genomics and/or genetics, from a recognized higher-education establishment;
  • Prior experience (3+ years) in analysis and interpretation of -omics data in academic or scientific research scenarios, supported by high-quality publications;
  • Familiarity with protein interaction/regulatory network collections and network/pathway based analysis methods. Experience with single-cell profiling approaches an advantage;
  • Ability to understand and communicate the output of computational biology research to multi-disciplinary scientific teams;
  • Expertise in Linux, statistical programming and data manipulation, using e.g. R/Bioconductor, Matlab, Python, plus good knowledge of contemporary database structures
  • Experience with version control and high performance computing, including cloud computing (e.g. AWS) and cloud HPC ; and
  • Verbal and written English language fluency. Proficiency in Spanish would be advantageous.

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Research Scientist I Phenotypic High Throughput Screening

Date Posted:
3/11/2017

Vertex

CA

Vertex Pharmaceuticals Incorporated seeks a High Throughput Screening Scientist for our San Diego, California location to design, develop, and implement disease translational, complex phenotypic in vitro assays for a variety of disease targets. The successful candidate will utilize the tools of the HTS discipline to reduce these assays to practice in an automated high throughput manner to identify new leads through primary screens or create clinical candidates from MedChem/SAR assays. The successful candidate will be expected to utilize assay measurement technologies of protein function in disease relevant cells and to contribute to identifying novel pharmacological and physiological insights to drug discovery.   Experience in developing cell based assays in the therapeutic areas of neuroscience, pain and ion channel biology/pharmacology is highly preferred. The successful applicant will contribute cell biology and ion channel/receptor pharmacology expertise to discovery projects and play a key role in the identification of chemical matter for novel targets and/or pathways for drug discovery.  

Requirements

Minimum Qualifications
•   Ph.D. in Cellular Biology, Pharmacology or related field with three years or more years of post-doctoral experience working with cellular assay development and pharmacology.
•   Experience involving the design, optimization and validation of target and phenotype based automated high throughput screening assays  
•   Demonstrated understanding of data analysis packages for automated high throughput screening, statistics and QC principles
•   Demonstrated ability to independently execute studies and provide reports and results to major stakeholders
•   Effective communication skills, both verbal and written, with the ability to present data at project team or other meetings as appropriate are essential
•   Demonstration of above experience through first author publications in high impact peer reviewed journals is expected.


Preferred Qualifications
•   Experience with ion channel pharmacology and electrophysiology
•   Development of model cellular systems; 3D co-cultures; induced pluripotent stem cells
•   Developing highly novel cellular screening approaches employing high content imaging, multi-parametric FACS and/or imaging analysis.  
•   Ability to navigate and be successful in a fast-paced, highly-matrixed work environment is preferred
•   A strong desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families, and society is preferred


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Research Scientist I Chemical Biology

Date Posted:
3/11/2017

Vertex

CA

Vertex Pharmaceuticals Incorporated is seeking a Research Scientist I for an exciting opportunity within its cross-functional chemical biology group.  The successful candidate would have a proven expertise in bio-conjugation methods and state of the art fluorescence detection and dye synthesis.  The preferred candidate would have a strong synthetic chemistry background and able to comfortably work at the interface between organic chemistry, molecular biology, and protein biophysics.  The successful candidate will be able to work independently, be able to multi-task, be able to work collaboratively in teams, and be adaptable to changing needs.  A strong desire to grow as chemist and the courage to challenge conventional wisdom are essential.
 
 
- Master’s degree in organic synthesis
- 3+ years of relevant experience applied fluorescence and/or bioconjugation methods
- Organize efforts to stay consistent with project priorities
- Demonstrated effective communication skills, both verbal and written to a broad range of audiences
- Ability to navigate and be successful in a fast-paced, highly-matrixed work environment
 
Preferred Qualifications:
- Ph.D. in organic synthesis
- 0-3 years of relevant experience applied fluorescence and/or bioconjugation methods
- A desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families and society

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Research Scientist II Elctrophysiologist

Date Posted:
3/11/2017

Vertex

CA

Vertex Pharmaceuticals Incorporated is offering an exciting opportunity to join the Pharmacology Group with a focus on the development of novel therapeutics. We are seeking a motivated, creative and innovative electrophysiologist with a deep understanding of ion channel biophysics and broad, hands-on experience using in vitro cellular electrophysiology techniques, with a particular focus on manual patch clamp, single channel recording and mechanism of action of ion channel pharmacology. A successful candidate will have demonstrated scientific expertise in ion channel function, measurement of ion channel activity, and application of electrophysiological recording techniques to characterize compound mechanism of action in support of drug discovery programs. 

Key responsibilities:
- Execute ion channel electrophysiology studies to elucidate the mechanism of action of compounds and mutations on channel behavior to support drug discovery projects.
- Analyze and interpret data and effectively document and communicate results.
- Provide technical expertise in ion channel biophysics and single channel and whole cell patch clamp electrophysiology.- Work effectively in a multi-disciplinary team environment and have excellent organizational and communication skills. 


Minimum Qualifications:
- Ph.D. (or equivalent) in Physiology, Pharmacology, or a related field with 2-5 years of drug discovery experience, preferably in a pharmaceutical/ biotechnology setting, or MS (or equivalent) in similar field with 5+ years of similar experience, or- BS (or equivalent) in similar field with 8+ years of similar experience.
- Extensive knowledge of ion channel biophysics and applications to drug discovery.
- In depth experience in the design, execution and interpretation of manual and/or automated patch-clamp electrophysiology studies.- Effective communication skills, both verbal and written.

Preferred Qualifications:
- Experience with CFTR chloride channels and epithelial ion transport is preferred.
- Ability to navigate and thrive in a fast-paced, highly-matrixed work environment.
- Strong desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families, and society.
 
Vertex is a global biotechnology company that aims to discover, develop and commercialize innovative medicines so people with serious diseases can lead better lives. In addition to our clinical development programs focused on cystic fibrosis, Vertex has more than a dozen ongoing research programs aimed at other serious and life-threatening diseases.

Founded in 1989 in Cambridge, Mass., Vertex today has research and development sites and commercial offices in the United States, Europe, Canada and Australia. For four years in a row, Science magazine has named Vertex one of its Top Employers in the life sciences. For additional information and the latest updates from the Company, please visit www.vrtx.com.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

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Research Scientist I Stem Cell Biology

Date Posted:
3/11/2017

Vertex

CA

Vertex Pharmaceuticals is seeking a highly motivated human cell biologist to join the Human Stem Cell Group. The successful candidate will be responsible for derivation and culture of adult progenitor and stem cells to support gene editing programs. Additional responsibilities also include optimization of differentiation protocols, development of transfection and transduction protocols, cell characterization using gene expression and protein labeling techniques. The successful candidate should also have an experience with human IPSCs culture and differentiation into neuronal and other lineages. He/She should be a highly motivated, hard-working person with good knowledge of cellular and molecular biology.


·    M.S. in cell biology, molecular biology or related area
·    Minimum 3 years of extensive hands on experience working with human primary stem cells and/or human IPSCs
·    Proficiency incell biology, histology and basic molecular biology techniques
·    Experience with viral transduction of human primary cells
·    Experience in FACS analysis
·    The successful applicant must be results orientated, self-motivated, and well-organized
·    Effective communication skills, both verbal and written
·    Exceptional multitasking skills, ability to work and deliver on several projects simultaneously
·    Ability to work independently and as part of a team in a matrix organization, ability to adapt to a time-line driven work environment
 
Preferred Qualifications:
·    PhD in cell biology or related area
·    Proven record of scientific accomplishments working with human stem cells
·    Basic understanding of the use of human cells in drug discovery processes is a plus
·    Experience in working in an industry environment is desired
·    A desire to be part of a highly innovative company that aims to transform the lives of people with serious diseases, their families, and society

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Scientist Cell Biologist

Date Posted:
3/11/2017

Vertex

MA

Vertex Pharmaceuticals is searching for an outstanding human cell biologist with a strong scientific background and proven accomplishments in deriving and differentiating human iPS cells into a variety of cell types (in particular neural cell types) for target validation, proof-of-concept experiments, and drug screening.   The ideal candidate will be responsible for the generation, maintenance, differentiation and characterization of human pluripotent stem cell-derived lines.  Extensive hands-on experience in working with primary human cells (especially neural cells), developing complex functional assays, high content imaging, and implementing quantitative image analysis using commercial and open-source software is preferred. The applicant will be part of a fast-paced drug discovery team. Good communication and people skills are required.


Key Responsibilities:


·     Reprogramming somatic cells to iPS cells and differentiating iPSC to various cell lineages


·     Characterizing differentiated cell populations by FACS, qPCR, and multi-electrode array


·     Develop and optimize high-content imaging protocols; experience with the Molecular Dynamics ImageXpress and Cellomics Arrayscan platforms (or systems of similar capacity and complexity) is preferred.

Minimum Qualifications

·     The ideal candidate will have a Ph.D. in Neurobiology or related science and minimum of 2-3 years of experience in primary human and stem cell biology and assay development


·     Strong technical background in neuroscience and imaging is preferred


·     Experience with iPS cell growth and differentiation particularly in feeder-free conditions is required; history with iPSC-derived cell-based assay systems is preferred


·     Excellent multi-tasking skills, attention to detail and ability to work independently are required


·     Excellent communication skills and ability to work in a highly-collaborative team environment


·    A desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families and society 


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Postdoctoral Fellow

Date Posted:
3/11/2017

Alexion

MA

Position Summary

 We are seeking a Postdoctoral Scientist to develop quantitative systems pharmacology (QSP) models of complement proteins and their role in disease pathobiology. The successful candidate will be an excellent cross-disciplinary scientist who uses cutting-edge modeling and simulations technologies to shed light on underlying pharmacological pathways, and has in-depth knowledge of using computational insights to design, execute and analyze critical experiments.  The Postdoctoral Scientist will integrate data from published literature and in-house experiments to build innovative QSP models of complement driven diseases and apply emerging insights to investigate novel protein targets. In addition, s/he will work closely with Alexion colleagues as well as with Key Opinion Leaders in the field of complement and coagulation biology. 

Principal Responsibilities

  • Build QSP models of complement pathways and their role in underlying disease pathobiology
  • Mine published literature to obtain and evaluate experimental data from in-vitro and in-vivo studies on complement systems. Stay current on published literature.
  • Collaborate with Alexion complement experts to develop a keen sense of experimental work being performed, identify data gaps and facilitate design of new experiments towards model refinement.
  • Ensure well annotated model codes with appropriate documentation for future use.
  • Present data at internal and external scientific meetings, and publish in major scientific journals

Qualifications

  • Ph.D. in bioengineering, biochemical engineering, computational biology or related field.
  • Experience in building ODE based systems pharmacology models.
  • Experience in using computational tools to design critical experiments.
  • Excellent oral and written communications skills with proven talent in communicating complex mathematical insights to biologists and clinicians.
  • Independent thinker and self-starter with talent in collaborating with multi-disciplinary teams.
  • Record of significant publications in top peer reviewed journals and presentations at major scientific meetings (preferably as first author).

Education

  • Ph.D. in bioengineering, biochemical engineering, computational biology or related field.

*LI-MW1 

 

Lexington, MA, United States
 

 

Alexion is a global biopharmaceutical company focused on developing and delivering life-transforming therapies for patients with devastating and rare disorders. Alexion developed and commercializes Soliris® (eculizumab), the first and only approved complement inhibitor to treat patients with paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS), two life-threatening ultra-rare disorders. As the global leader in complement inhibition, Alexion is strengthening and broadening its portfolio of complement inhibitors, including evaluating potential indications for eculizumab in additional severe and ultra-rare disorders. Alexion’s metabolic franchise includes two highly innovative enzyme replacement therapies for patients with life-threatening and ultra-rare disorders, Strensiq® (asfotase alfa) to treat patients with hypophosphatasia (HPP) and Kanuma™ (sebelipase alfa) to treat patients with lysosomal acid lipase deficiency (LAL-D). In addition, Alexion is advancing the most robust rare disease pipeline in the biotech industry, with highly innovative product candidates in multiple therapeutic areas.
As a leading employer in our industry, Alexion is proud to offer a highly competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, 401(k) with company match, tuition reimbursement, relocation assistance and much more. To learn more about Alexion, please visit www.alexionpharma.com or download our App for iPhones and Blackberries.

Alexion is an Equal Opportunity /Affirmative action employer

Alexion participates in E-Verify process. To learn more, please click on attached document(s)

English/Spanish


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Computational Scientist

Date Posted:
3/11/2017

Evelo

MA

Computational Scientist

 

Evelo Biosciences is seeking an experienced Computational Scientist to join our talented and dedicated team of scientists and engineers in changing the lives of patients around the world in a fast-paced environment. The successful candidate will drive the use of computational approaches to advance cutting-edge programs and the discovery and validation of novel targets and biomarkers in preclinical and clinical drug discovery and development. Must have a deep passion for improving health outcomes for patients.

 

Responsibilities:

 

The successful candidate will advance Evelo’s pipeline in discovery, preclinical and clinical stages by accomplishing the following:

  • Collaborative with therapeutic area scientists and clinical researchers in applying state-of-the art informatics and data mining approaches
  • Design and execute on the analysis of in vivo and in vitro experiments
  • Design and execute on the analysis of in silico experiments
  • Identify and evaluate external collaborators, novel methods and emerging expertise
  • In-depth characterization of cellular and human microbiome responses in preclinical and clinical models
  • Share and contribute scientific and technical know-how and experience with team members

 

Qualifications:

  • D. in a relevant scientific discipline or technology area, particularly in Computational Biology, Computer Science, Data Science
  • In-depth knowledge and extensive hands-on experience with genomics, metagenomics, microbiome or electronic medical records
  • Minimum of 5 years of post-graduate or biotech/pharma experience in analyzing large data sets with advanced analytics approaches
  • Hands-on experience with scientific computing capabilities including high performance computing (HPC), bioinformatics pipelines, natural language processing and machine learning
  • Versed in traditional and emerging mathematics and methods to model high dimensionality data sets
  • Knowledge of the pharmaceutical drug discovery and development process with a relevant track record, including preclinical and clinical drug development
  • Proven track record of scientific accomplishment and contributions to the field of computational sciences
  • Exceptional scientific reporting and presentation skills in translating complex statistical methods into readily understood and valuable results
  • Demonstrated ability to work collaboratively with research project teams and clinical development teams
  • Dynamic, flexible, well-organized, pro-active, collaborative-minded individual passionate about improving health outcomes for patients around the world

 

 

 


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imuunologist

Date Posted:
3/11/2017

Evelo

MA

Evelo is seeking an experienced Scientist to join our Immunology research team to advance cutting-edge microbiome therapeutic programs. This role will provide Immunology expertise towards developing targeted, microbe-based, immune tolerizing and anti-inflammatory therapeutics to enable successful IND filings. This individual will support and expand our research strategy to conceptualize, design and execute pivotal in vitro and in vivo proof of concept studies in pre-clinical models of autoimmunity and inflammation. Significant cross-functional collaboration with a talented and dedicated group of scientists including microbiologists, cell biologists and  immunologists, will ensure a diverse exposure to the drug discovery process.

 

Responsibilities:

The successful candidate will advance several aspects of Evelo’s lead preclinical microbial therapeutic programs, using their targeted skill set to accomplish the following responsibilities:

  • Design and execution of well-controlled in vitro and in vivo immunologyexperiments
  • In-depth characterization of cellular and humoral immune responses in various mouse models of autoimmunity, inflammation and immune tolerance in general
  • Develop, execute, and trouble-shoot immunoassays, including in vitro cellular stimulations, flow cytometry, ELISA, and microscopy
  • Share and contribute scientific and technical know-how and experience with team members

 

Qualifications:

  • D. in the domain of immunology, preferably with focus in autoimmunity, inflammation, tolerance, or vaccines.
  • 3-6 years of post-doctoral or biotech/pharma experience in developing and conducting laboratory research
  • In-depth knowledge and extensive hands-on experience in mouse models of cellular autoimmunity, primary immune cell characterization, immunoassay development, and protein chemistry
  • Proven track-record of scientific accomplishment and contributions to the field of autoimmunity or tolerance research
  • Exceptional scientific reporting and documentation proficiency
  • She or he should be a dynamic, independent, flexible, well-organized, pro-active, collaborative-minded individual interested in contributing in a hands-on and strategic role to excellent research science in a fast-paced entrepreneurial environment.

 


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in vitro immunology

Date Posted:
3/11/2017

Evelo

MA

 In Vitro Immunology Scientist 

 

Evelo Biosciences, founded by Flagship VentureLabs has established the leading therapeutics discovery and development based on the human immuno-microbiome. We are developing onco-microbials for the treatment of cancer and immuno-microbials for the treatment of autoimmune and inflammatory diseases.

 

We are seeking talented and dedicated Scientists, who are  interested in joining a highly dynamic and intellectually challenging team. This exciting role will afford Scientists the opportunity to be intimately involved in the implementation of cutting-edge research programs in a multifunctional biology laboratory.   Successful candidates will posses expertise in immunology and/or immuno-oncology and a proven ability to multi-task within scope. 

 

Primary responsibilities:

 

- Design and conduct in vitro immune cell-based assays for screening, discovery, and mechanistic analysis of microbial drug candidates

- Design and implement rigorous ex vivo assays to understand immunological mechanism of action 

- Develop and implement multi-parameter flow cytometry-based immune phenotyping assays, cell sorting assays, and multiplex cytokine profiling assays

- Actively participate on project teams and collaborate across interdisciplinary R&D programs

-Independently design rigorous experiments, interpret data, and communicate findings in well-articulated presentations

 

Desired capabilities, skills and experience:

 

- Candidates must have a background in immunology, immuno-oncology, drug discovery with experience in microbiome field a plus

- Proficient in flow cytometry techniques, cytokine/chemokine profiling on Luminex or similar platform

- Experience with primary mammalian cell culture, cell proliferation assays, and/or metabolic assays

- Experience with ex vivo rodent sample processing, including RNA/DNA extraction, immunophenotyping, and immunohistochemistry

- Highly motivated and results driven individual with a passion for working in a fast-paced and evolving organization

- Strong oral and written  communication as well as excellent collaboration & interpersonal capabilities

- Outstanding team player with ability to work in groups as well as independently 

- Adept at problem solving

 

Education and experience requirements:

 

- Ph.D. in immunology or related field

- 3-5 years of relevant experience in biopharmaceutical industry strongly preferred

 


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Scientific Strategy Corporate Development Fellowship

Date Posted:
3/11/2017

Evelo

MA

Evelo Biosciences is dedicated to transforming immunotherapy therapy through a deep understanding of the immuno-microbiome, the intimate coevolved metasystem of the host immune system and the microbiome.  Evelo is developing therapies designed to treat cancer, inflammatory, and autoimmune disease through modulating the systemic immune system.  Evelo’s platform deciphers microbes’ ability to modulate local and systemic immune function, evaluates microbes’ efficacy in disease models, and creates pharmaceutically acceptable forms of microbes for development and clinical translation.  Evelo was founded in 2015 by Flagship VentureLabs®, the innovation foundry of Flagship Pioneering. Evelo has an initial capital commitment of $100+ million and is considered to be one of the most exciting companies in the microbiome space today.

 

2017 SUmmer fellowship

Evelo is seeking a talented PhD or MD student or post graduate to join us for the summer of 2017. Evelo is a highly dynamic and intellectually challenging work environment.  The successful candidate will be a self-starter, scientifically and intellectually curious, entrepreneurial, and a creative problem solver.

 

Fellow will partner closely with Evelo’s Head of Scientific Strategy on a variety of projects, including:

  • Surveillance of scientific fields and sourcing interesting and innovative technologies from academia
  • New program planning and product building, including the drafting of R&D plans
  • Intellectual property strategy related to Evelo’s current and future products
  • Regulatory strategy and clinical translation of Evelo’s products

 

Program Details

  • Full-time Fellowship from June 6, 2017 – September 1, 2017
  • Fellow will be based out of Evelo’s headquarters at 620 Memorial Drive, Cambridge, MA
  • Fellow will receive a stipend

 

Fellows will be able to

  • Influence a growing biotech
  • Expand professional network
  • Develop marketable skills for careers in the commercialization of science

 

Qualifications

  • Current PhD, MD, or MDP student or post-graduate
  • Demonstrated passion and business acumen for translation and commercialization of science
  • Clear communication skills, creativity, and independence
  • Deep scientific or business background in the life sciences
  • Knowledge and expertise in immunology, cancer biology, neurobiology, or microbiology a plus

 

Please submit your cover letter and resume at: https://evelobio.recruiterbox.com/jobs/fk06qcg

For more information about Evelo Biosciences, please visit http://www.evelobio.com


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Biomedical Engineer

Date Posted:
3/10/2017

Kelly Services

CA

Biomedical Engineer Location: San Jose, CA Contract Position Job Description: Our Advanced Sensors Group is expanding and looking for a bio-sensor engineer with bio-medical and optical sensor experience. He/she will be working closely with cross functional team across company for successful product development. Candidate will also be a core member of the team and will be providing status updates to customers, as well as top level executives. Lead R&D efforts for design of bio-medical optical sensors. Develop thorough understanding of human body physiology, focused for wearable sensors technology. Understand optimizations, trade-offs, error sources, human population variations with respect to biological signal of interest. Communicate and educate cross-functional team on design choices, optimization and design pit-falls As part of the product definition team develop optical and electrical requirements for the proposed sensing solution. Advice groups on possible solutions of ongoing sensor focusing on bio-medical issues Qualifications: PhD degree relative to Bio-Sensors, preferable with tissue optics experience 5+ years of experience in the design of sensor systems. Preferably in wearables. Understanding of human physiology, Tissue Optics and its challenges. General modeling and analysis of systems. Experience in MATLAB, Solidworks/Autocad (preferred) Experience is data collection, data analysis, understanding trends and error sources Provide direction to user studies group for repeatable and accurate user data that is essential to algorithm development. Lead R&D projects on creating future products. Excellent written and verbal communication skills. Travel Requirements – 10-20% International and domestic.


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Biologists and Chemists multiple positions

Date Posted:
3/10/2017

Kelly Government Solutions

OH

BS, MS, PhD Biologists and Chemists - Government Research Facility - Columbus, OH Kelly Government Solutions is a strategic supplier and business partner to the federal government and its key suppliers. We are currently seeking BS, MS, and PhD Scientific Analysts to provide support of a new cutting edge laboratory based technology in Columbus, OH. These multiple government contract positions are: -Contract length: not known at this time. -Contract Hours: Full time and Part time opportunities (25- 40 hours/week) / flexible schedules. -May require some weekend and evening work based on projects. -Benefits are available to purchase through Kelly Services due to the Affordable Care Act. TASKS/SERVICES: The contractors shall: 1. Perform literature reviews and summaries of reviewed information related to the new technology, with subsequent preparation of protocols for technology use. 2. Participate in experimental execution of the technology in lab, with subsequent data reduction, data review, and data compilation adhering to accepted practices. 3. Log daily activities during literature review and laboratory efforts. 4. Work independently in a laboratory environment, displaying an interest in successfully achieving the goals of the technology research and implementation. 5. Maintain good work attendance record and be punctual for all project work. REQUIREMENTS: The contractors must have: 1. PhD in Chemistry, Microbiology, and/or Molecular Biology with 5-10 years of experience in a lab-based facility. MS or BS in Chemistry with 1+ years of experience in a lab-based facility are also welcome. 2. Proven ability to conduct experiments according to provided procedures. 3. Ability and willingness to work in biological laboratories and adhere to established safety guidelines. 4. Sufficiently medically fit to work in the laboratory to perform assigned duties. 5. Proficient with Microsoft Windows operating system and Microsoft Office, as well as general online research capabilities (use of search terms, etc). 6. Must be eligible to obtain security clearance. 7. Strong verbal and written communications skills; strong attention to detail. PLEASE APPLY ONLINE Note that the phone number for our Kelly Scientific branch is not listed. Due to the high volume of inquiries, we regret that we cannot accept phone calls. All qualified candidates will be contacted.


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Scientific Grants Program Analyst

Date Posted:
3/10/2017

Kelly Government Solutions

MD

Scientific Grants Program Analyst - NIH - Bethesda, Maryland Kelly Government Solutions is a strategic supplier and business partner to the federal government and its key suppliers. Through our partnership with the National Institutes of Health, Kelly Government Solutions offers administrative, IT, engineering, scientific, and healthcare professionals the opportunity to work with one of the most prestigious research organizations in the world. We are currently seeking a GRANTS PROGRAM ANALYST to work on-site at the National Institutes of Health in Bethesda, MD. Bethesda is near Washington, DC. This is a full time, long-term contract position which offers: - Competitive salary with comprehensive benefits package - Opportunity to work at NIH, the world's foremost medical research center - Learn more about what Kelly can do for you at www.kellygovernmentsolutions.com National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) National Institutes of Health (NIH) Bethesda, Maryland Administrative position TASKS/SERVICES. The contractor shall: 1. Identify scientific and management issues and policies related to designated programs. 2. Identify policy issues that impact MoTrPAC (the Molecular Transducers of Physical Activity Consortium); work with Program staff to determine appropriate approaches and positions for handling these issues. 3. Contribute to the creation of programmatic documents. 4. Prepare materials such as handouts to advertise the availability of MoTrPAC resources for the research community, posters for scientific meetings, and PowerPoint presentations for senior program leadership. 5. Create content for the NIAMS-specific projects and NIH Common Fund program websites. 6. Read, interpret, analyze and condense scientific material from a variety of sources for presentation. 7. Work with extramural program directors and other staff to compile a report of ongoing and emerging scientific areas; create search criteria for locating scientific, program and related information on the internet and through internal NIH database searches. 8. Develop meeting agendas for MoTrPAC working group meetings and related meetings. 9. Attend and support NIH Common Fund staff, working group, Project Team and Steering Committee meetings. 10. Devise methods to ensure operational plans are developed by the appropriate staff to help implement scientific priorities and policies; track action items and tasks; provide deadline reminders to Program staff; maintain spreadsheets of relevant information. 11. Maintain a running document of milestones, timelines, deliverables and deadlines related to the MoTrPAC. 12. Develop reporting templates for gathering scientific and programmatic information re-lated to the MoTrPAC and other extramural research activities. 13. Track receipt of MoTrPAC steering committee reports; edit and finalize materials for submission to the NIH Office of Strategic Coordination. 14. Gather meeting minutes and assist with organizing specific MoTrPAC work stream tel-econferences with the aim of keeping MoTrPAC on track and on schedule. 15. Verify accuracy of human subjects enrollment data from Interim Reports; enter information into Population Tracking tables into the NIH eRA module. 16. Run QVR searches as part of an analysis to measure the impact of NIH-funded programs, including the MoTrPAC; generate and analyze data to produce spreadsheets and graphs for use by program staff. 17. Proofread and edit outgoing materials, including Program and Funding Opportunities Announcements and press releases, to ensure that requested changes have been made. 18. Review, monitor, analyze and evaluate financial, narrative and statistical reports and scientific and programmatic data submitted to NIH by grantees and contractors. 19. Determine accuracy of information to develop SOPs. 20. Update statistical data from grant applications. 21. Collaborate with staff to develop daily, short- and long-range direction for assigned programs and special projects. 22. Remain alert to program progress and effectiveness and work with staff to adjust the approach or direction and priorities of assignments. 23. Develop and implement measures to ensure coordination within the NIAMS, and within other NIH organizations affected by assigned programs, including MoTrPAC. REQUIREMENTS. The contractor must have: 1. Master’s degree in Science or related with 3+ years of experience in TASKS above. 2. Bachelor's degree with 5 years of experience will be considered. 3. Excellent proactive, proven project management and problem solving skills. 4. Expertise in effective/efficient meeting management and administrative tasks. 5. Strong analytical, communications skills, both verbal and written. 6. Excellent leadership, analytical, organizational and time management skills. PLEASE APPLY ONLINE. Note that the phone number for our NIH branch is not listed. Due to the high volume of inquiries, we regret that we cannot accept phone calls or emails. All qualified candidates will be contacted.


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Biochemist

Date Posted:
3/10/2017

Kelly Government Solutions

MD

Biochemist - NIH - Bethesda, Maryland Kelly Government Solutions is a strategic supplier and business partner to the federal government and its key suppliers. Through our partnership with the National Institutes of Health, Kelly Government Solutions offers administrative, IT, engineering, scientific, and healthcare professionals the opportunity to work with one of the most prestigious research organizations in the world. We are currently seeking a BIOCHEMIST to work on-site at the National Institutes of Health in Bethesda, MD. Bethesda is near Washington, DC. This is a full time, long-term contract position which offers: - Competitive salary with comprehensive benefits package - Opportunity to work at NIH, the world's foremost medical research center - Learn more about what Kelly can do for you at www.kellygovernmentsolutions.com National Heart, lung and Blood Institute (NHLBI) Intramural Administration Management Branch (IAMB) Imaging Probe Development Center (IPDC) National Institutes of Health (NIH) Bethesda, Maryland Main Campus, lab position TASKS/SERVICES. The contractor shall: 1. Culture and maintain cells for in vitro assays. 2. Perform in vitro radioligand binding assays and immuno assays. 3. Conduct experiments including performing synthetic, optical, radionucleotide and biochemical studies; produce known and novel agents. 4. Support in vivo biodistribution studies. 5. Purify proteins and bioconjugation of fluorescent and chelating groups. 6. Collaborate with chemists within Imaging Probe Development Center (IPDC) for the preparation and testing of synthesized probes. 7. Produce intermediaries and final products in pre-determined amounts and purities. 8. Perform analytical validation and testing of compositions. 9. Propose novel solutions to problems encountered during research; develop and present plans for solutions. 10. Perform literature searches in support of research. 11. Collect, analyze and interpret data and findings. 12. Prepare summaries and reports based on findings and results. 13. Attend meetings and present results and findings to staff. REQUIREMENTS. The contractor must have: 1. MS in Biochemistry or related with 4+ years of experience as described in TASKS. 2. BS with 6 years of experience will be considered. 3. Experience in tissue culture techniques and in vitro assays. 4. Ability to understand software packages for KD determination. 5. Strong verbal and written communications skills. 6. Excellent analytical, organizational, interpersonal and time management skills. PLEASE APPLY ONLINE. Note that the phone number for our NIH branch is not listed. Due to the high volume of inquiries, we regret that we cannot accept phone calls or emails. All qualified candidates will be contacted.


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Experimental Therapeutics Program Analyst

Date Posted:
3/10/2017

Kelly Government Solutions

MD

Experimental Therapeutics Program Analyst *** NIH *** Rockville, MD Kelly Government Solutions is a strategic supplier and business partner to the federal government and its key suppliers. Through our partnership with the National Institutes of Health, Kelly Government Solutions offers administrative, IT, engineering, scientific, and healthcare professionals the opportunity to work with one of the most prestigious research organizations in the world. We are currently seeking an Experimental Therapeutics Program Analyst to work with the National Institutes of Health in Rockville, MD. This is a long-term contract position which offers: - Competitive salary with comprehensive benefit package - Opportunity to work at NIH, world's foremost medical research center - Learn more about what Kelly can do for you at www.kellygovernmentsolutions.com TASKS/SERVICES : The contractor shall: (1) Provide support for activities of the National Cancer Institute's (NCI) Experimental Therapeutics (NExT) Program to develop novel molecularly targeted agents for cancer through the Chemical Biology Consortium (CBC) discovery pipeline. (2) Work with staff on the evaluation, review and prioritization of drug discovery/development projects within the NExT/CBC portfolio. (3) Provide day-to-day decisions necessary to meet drug discovery/development project objectives with project leaders and portfolio managers. (4) Work with staff on the coordination and conduct of meetings with project teams, project managers, NCI senior management staff, and external experts. (5) Develop and review discovery/development project plans with project managers, project leaders, and portfolio managers. (6) Provide analysis, advice and ideas about drug targets and pathways to Special Assistant to the Director of the Division of Cancer Treatment and Diagnosis. (7) Prepare reports, proposals and presentations. REQUIREMENTS : The contractor ideally would have: (1) Ph.D. in Molecular Biology, Medicinal Chemistry, Developmental Therapeutics, Oncology, Biomedical Research, Pharmacology, or a related discipline. (2) Previous experience in research and/or administrative experience in an academic setting or in a pharmaceutical, biotechnology, or medical device industry. (3) Understanding of the basic fundamentals of project and portfolio management. (4) Knowledge of SBIRs and grant application/review process. (5) Knowledge of medicinal chemistry and drug design. (6) Proficiency in Microsoft Office Project and Microsoft Office Suite (MS Word, Excel, PowerPoint, Outlook), SharePoint and other data management systems. (7) Highly effective problem solving, planning and organizational skills. (8) Excellent people skills and strong communication skills, both oral and written. (9) Ability to function collaboratively within a team setting. (10) Attention to detail and follow through. PLEASE APPLY ONLINE Note that the phone number for our NIH branch is not listed. Due to the high volume of inquiries, we regret that we cannot accept phone calls. All qualified candidates will be contacted.


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Scientific Program and Communications Analyst Cancer Diagnosis Center

Date Posted:
3/10/2017

Kelly Government Solutions

MD

Scientific Program and Communications Analyst *** NIH *** Rockville, MD Kelly Government Solutions is a strategic supplier and business partner to the federal government and its key suppliers. Through our partnership with the National Institutes of Health, Kelly Government Solutions offers administrative, IT, engineering, scientific, and healthcare professionals the opportunity to work with one of the most prestigious research organizations in the world. We are currently seeking a Scientific Program and Communications Analyst to work with the National Institutes of Health in Rockville, MD. This is a long-term contract position which offers: - Competitive salary with comprehensive benefit package - Opportunity to work at NIH, world's foremost medical research center - Learn more about what Kelly can do for you at www.kellygovernmentsolutions.com TASKS/SERVICES : The contractor shall: Communications (1) Work with staff to coordinate projects, events, activities and initiatives within the Cancer Diagnosis Program (CDP). (2) Help manage the communications effort for the Cancer Diagnosis Program. (3) Design and coordinate systems for communication among staff to facilitate the efficient flow of information relating to projects and program activities, including databases and the use of SharePoint. (4) Coordinate the preparation of a variety of documents such as outside activities (Form520), training requests, individual/mass mailings, correspondence, reports and various other forms. (5) Develop a plan to improve the outreach, education, and interaction strategies of CDP. (6) Implement the plan to ensure that the communications goals are met. (7) Manage the Cancer Diagnosis Program (CDP)/ Biorepositories and Biospecimen Research Branch (BBRB) Listserv and use it to promote news, announcements and other relevant information of the office. (8) Work with the Office of Communications and Public Liaison to achieve the communications goals of CDP. (9) Develop new educational materials for CDP stakeholders, including patients, researchers and healthcare professionals. (10) Manage the CDP public website & the BBRB public website, including developing content, and general administrative duties. (11) Lead efforts to improve the CDP website so that it can better meet the use and the goals of the communications plan. (12) Lead efforts to gather new content from CDP staff to keep the websites up to date and to develop timely content for the website. (13) Manage social media accounts for CDP (including but not limited to Twitter, LinkedIn, etc.). (14) Lead efforts to expand the use of social media. (15) Develop and implement a plan to use social media channels to keep CDP stakeholders and the research community informed and up to date. Administrative (1) Attend internal/external meetings and scientific conferences; coordinate logistical planning for meetings/teleconferences; take notes and prepare minutes for scientific meetings related to Cancer Diagnosis meetings and programs. (2) Schedule and make arrangements for meetings and events within and outside CDP; reserve space; set schedule and times; contact participants; transmit agenda and materials for discussion. (3) Prepare and finalize meeting agendas and other materials based on staff and consultant input. (4) Prepare and distribute presentation materials such as reports, summaries, tables, graphs and slides. (5) Take a proactive role in tracking action items and tasks; provide deadline reminders to staff; maintain spreadsheets of relevant information for grants, contracts and other programs. (6) Request information from and provide e-mail, phone and written responses to NCI staff, NIH staff, other government agencies and community members. (7) Prepare presentations, reports, summaries, databases and other documents related to the accumulation and analysis of data. (8) Respond to inquiries and requests for general information from internal and external sources. (9) Manage the CDP SharePoint site. (10) Work with staff to ensure that new staff members are granted appropriate permissions to the CDP SharePoint site. (11) Troubleshoot issues with SharePoint use. (12) Manage and create new sections of the SharePoint site as needed. (13) Serve as the Lead Safety Coordinator for Safety and Security. Database Management (1) Develop tools using programs such as Excel, SharePoint, Access and Filemaker to create usable databases for CDP staff for grants, contracts, clinical protocols and reviews of same. (2) Manage various databases in Microsoft Access, Filemaker Pro, and Oracle. (3) Lead efforts to improve database tools and other programs by coordinating and hosting meetings with database stakeholders. (4) Troubleshoot issues with the databases as needed. (5) Develop ad-hoc reports, queries and other deliverables within the databases. (6) Maintain accuracy of data files via multiple software systems, including computerized procurement reports and communication programs. REQUIREMENTS : The contractor must have: (1) Master’s degree in a related discipline; two (2) years of specialized experience plus a Bachelor’s degree is equivalent to a Master’s degree. (2) Minimum of two (2) years of related communications and/or project management experience. (3) Background in a scientific field; experience with communicating science or scientific policy. (4) Expertise with Microsoft Access (5) Skill in data analysis and presentation. (6) Ability to adapt and create tools to analyze and evaluate projects. (7) Strong communications skills, both oral and written. (8) Excellent analytical, organizational and time management skills. (9) Ability to anticipate staff needs in the varied avenues of research, analysis and reporting, and create alternative processes for addressing tasks where appropriate. PLEASE APPLY ONLINE Note that the phone number for our NIH branch is not listed. Due to the high volume of inquiries, we regret that we cannot accept phone calls. All qualified candidates will be contacted.


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Clinical Molecular Biologist

Date Posted:
3/10/2017

Kelly Government Solutions

MD

Clinical Molecular Biologist ** DNA Extraction, Sanger Sequencing, & CLIA Laboratory ** NIH ** Bethesda, MD Kelly Government Solutions is a strategic supplier and business partner to the federal government and its key suppliers. Through our partnership with the National Institutes of Health, Kelly Government Solutions offers administrative, IT, engineering, scientific, and healthcare professionals the opportunity to work with one of the most prestigious research organizations in the world. We are currently seeking a Clinical Molecular Biologist to work in a CLIA-certified clinical laboratory within the National Institutes of Health in Bethesda, MD. This is a long-term contract position which offers: - Competitive salary with comprehensive benefit package - Opportunity to work at NIH, world's foremost medical research center - Learn more about what Kelly can do for you at www.kellygovernmentsolutions.com TASKS/SERVICES : The contractor shall: Molecular Genetics Assays (1) Develop, validate and perform a variety of molecular assays in Clinical Laboratory Improvement Amendments (CLIA)-certified clinical laboratory to determine the DNA sequence changes that underlie inherited eye diseases; adhere to CLIA guidelines and mandates. (2) Interpret the results of DNA diagnostic assays; determine the significance for the patient’s health care management; provide written reports of assay results. (3) Develop and implement novel kits and technologies, including next generation sequencing, to aid in the analysis of microsatellite and other polymorphic loci in patient samples; implement liquid handling robotics to advance experimental efficiency. (4) Stay current with emerging genomics technologies and bioinformatics tools to assess the significance of DNA sequence variants. (5) Work with staff in the Ophthalmic Genetics and Visual Function Branch (OGVF) to apply standard molecular biological techniques to further experimentation including RT-PCR, molecular cloning, site-directed mutagenesis, primer design, Sanger sequencing, next-generation sequencing and all forms of nucleic acid purification. (6) Collaborate with other NEI laboratory staff, including members of the eyeGENE laboratory. (7) Prepare and present scientific and technical reports in peer-reviewed journals and at national/international conferences. Laboratory Management (1) Prepare Standard Operating Protocols (SOPs); maintain laboratory compliance and all appropriate paperwork in accordance with the regulations of the Clinical Laboratory Improvement Amendments (CLIA) of 1988. (2) Manage databases and repositories of patient samples; interact with physicians and investigators to ensure the proper sample tracking, processing and maintenance. (3) Maintain logs of all reagents and consumables in a CLIA-sanctioned manner. (4) Maintain temperature monitoring of freezers that house patient samples; respond to freezer failures 24 hours per day. (5) Maintain stocks of reagents and management of specialty equipment maintenance; interact with outside vendors. (6) Work with staff to train junior staff, collaborating investigators and summer interns in molecular genetics assays and the special requirements of clinical laboratories. Planning and Design of Research (1) Collaborate on the planning and design of research; analyze the results of ongoing laboratory experiments; assess and analyze pertinent research outside of NEI; collaborate on the future direction of laboratory experimental work. (2) Analyze data and results from current experiments; identify investigative outcomes relevant to research; assess the overall progress of the research and solicit input from other scientists; develop, design and recommend further experimental work and approaches to research. (3) Revise the specific experimental techniques or protocols to improve work methods or to accommodate revised experiment designs. (4) Participate in scientific staff assessments of research during laboratory meetings; exchange information and assessments with other scientists, collaborators from outside the laboratory and technical support staff. (5) Conduct literature searches; select and analyze data from pertinent literature; determine its applicability and relevance to the Section’s on-going research. (6) Maintain computerized files of laboratory protocols and data. REQUIREMENTS : The contractor ideally would have: (1) Ph.D. in a scientific discipline. Three (3) years of specialized experience plus a Master’s degree is equivalent to a Ph.D. Five (5) years of specialized experience plus a Bachelor’s degree is equivalent to a Ph.D. (2) Minimum of four (4) years of experience in a CLIA laboratory. (3) Hands-on experience in DNA sequencing. (4) Hands-on experience with DNA and RNA isolation from human blood, long range PCR, real-time quantitative PCR, gel electrophoresis, Sanger sequencing, STR analysis and other basic molecular biology. (5) Knowledge of bioinformatics tools and programs such as Sequencer, GeneMapper and online resources including those from NCBI, the UCSC genome browser and other specialty applications. (6) Extensive experience in next-generation sequencing technologies, database searching and record keeping. (7) License or certification for clinical laboratory. (8) Strong communications skills, both oral and written. (9) Excellent analytical, organizational and time management skills. PLEASE APPLY ONLINE Note that the phone number for our NIH branch is not listed. Due to the high volume of inquiries, we regret that we cannot accept phone calls. All qualified candidates will be contacted. Once you have applied online to the position, if you have specific questions, you may contact us at kellyrecruiter@mail.nih.gov


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Oncology Drug Discovery and Development Program Manager

Date Posted:
3/10/2017

Kelly Government Solutions

MD

Oncology Drug Discovery and Development Program Manager *** NIH *** Bethesda, MD ***Please Note Modified Job Title, Tasks, and Requirements*** Kelly Government Solutions is a strategic supplier and business partner to the federal government and its key suppliers. Through our partnership with the National Institutes of Health, Kelly Government Solutions offers administrative, IT, engineering, scientific, and healthcare professionals the opportunity to work with one of the most prestigious research organizations in the world. We are currently seeking an Oncology Drug Discovery and Development Program Manager to work with the National Institutes of Health in Bethesda, MD. This is a long-term contract position which offers: - Competitive salary with comprehensive benefit package - Opportunity to work at NIH, world's foremost medical research center - Learn more about what Kelly can do for you at www.kellygovernmentsolutions.com TASKS/SERVICES : The contractor shall: (1) Lead and manage drug discovery and development project teams. (2) Establish and maintain communication with Chemical Biology Consortium (CBC) Centers; oversee the NCI Experimental Therapeutics (NExT) Program pipeline, with an emphasis on cross-site CBC drug discovery projects. (3) Prepare documents and collect metrics on NExT pipeline for high level presentations to key stakeholders. (4) Facilitate project team discussions; identify gaps and inefficiencies to address seamless progression of projects in the NExT pipeline. (5) Contribute to a project team through intellectual, scientific engagement, and participation at team meetings. (6) Coordinate the external and NCI parties to establish agreements with CBC Centers and to make adjustments for changes in scope or scientific direction of projects in the pipeline. (7) Manage project team deliverables (e.g., reports, assay results, synthesized compounds of interest); ensure that all team members have access to scientific data. (8) Collaborate with staff on the preparation of project team reports and/or presentations; compile quarterly reports. (9) Interact with scientists as needed to help overcome technical hurdles or provide additional insights or expertise. (10) Interpret and evaluate scientific data, results and conclusions. REQUIREMENTS : The contractor ideally would have: (1) Ph.D. in a related discipline. (2) Minimum of ten (10) years of experience in the field of pharmaceutical and biotech business. (3) Minimum of five (5) years of experience working in a drug discovery project team environment, preferably in the pharmaceutical or biotech industry. (4) Demonstrated ability to interact constructively with other drug discovery scientists (biologists, chemists, pharmacologists, etc.) on a complex research project. (5) Comprehensive understanding of the small molecule drug discovery process, from assay development and screening through late-stage optimization and candidate selection. (6) Expertise in biochemical, cellular or animal pharmacology, with in-depth knowledge of protein biochemistry, enzymology, and structural biology, cancer target biology, molecular characterization of cell lines, and development of quantitative cellular assays, and/or pharmacokinetic analysis in rodents, selection and use of relevant efficacy for oncology, understanding of animal physiology and toxicology. (7) Demonstrated ability to rigorously interpret and evaluate scientific data, results and conclusions. (8) Recognized leadership skills and abilities in a project team setting, with the ability to manage teams or collaborations with participants based at different institutions and geographic locations. (9) An understanding of project management concepts and principles and experience working with them. (10) Recognized scientific standing demonstrated through a record of peer-reviewee publications. (11) Strong communications skills, both oral and written. (12) Excellent analytical, organizational and time management skills. PLEASE APPLY ONLINE Note that the phone number for our NIH branch is not listed. Due to the high volume of inquiries, we regret that we cannot accept phone calls. All qualified candidates will be contacted.


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Molecular Biologist

Date Posted:
3/10/2017

Kelly Government Solutions

MD

Kelly Government Solutions is a strategic supplier and business partner to the federal government and its key suppliers. Through our partnership with the National Institutes of Health, Kelly Government Solutions offers administrative, IT, engineering, scientific, and healthcare professionals the opportunity to work with one of the most prestigious research organizations in the world. We are currently seeking a Molecular Biologist to work with the National Institutes of Health in Baltimore, MD. This is a long-term contract position which offers: - Competitive salary with comprehensive benefit package - Opportunity to work at NIH, world's foremost medical research center - Learn more about what Kelly can do for you at www.kellygovernmentsolutions.com TASKS/SERVICES. The contractor shall: Investigate molecular and cellular mechanisms of immune cell aging in human (BLSA participants) and mouse model. Employ cutting edge genomic methods such as RNA-seq, ChIP-seq, microarray to identify genes and epigenetic changes that are altered expressed in old lymphocytes and monocytes, and confirm the alteration of expression by specific real time RT-PCR. Determine the size of TCR repertoire including both TCR alpha and beta genes, and their change with age in both CD4 and CD8 T cells and their subsets using the next generation sequencing technique. Analyze the telomere length changes in BLSA participants by Southern blot, quantitative PCR or qFISH . Process human blood samples; conduct routine primary immune cell culture in vitro . Perform immune cell phenotypic and functional analysis by flow cytometry; isolate specific lymphocyte subset from blood by magnetic isolation and cell sort. Genotype various genetically altered mouse strains and isolate immune cells from these mice for subsequent functional studies. Conduct proteomic analysis of selected proteins and its associated proteins. Design, initiate and conduct specific research projects described above. Participate in and present ongoing research and findings at weekly Lab and section meetings. Write and edit scientific papers. Present paper/abstract/poster at lab meeting and scientific meetings/conferences. Operate and maintain sophisticated and innovative instruments such as fluorescent microscope, flow cytometry, and next generation sequencing to perform tests, analyses and other laboratory procedures; perform routine laboratory maintenance. Schedule and maintain an accurate research tracking system and database for all research activities, daily records of experiments and results, including research documentation. Ensure that research stock supplies and reagents are kept stocked; obtain quotes for laboratory supplies, services and equipment needed to conduct research; prepare purchase requests for these items and submit to primary investigator and/or lab manager for approval. REQUIREMENTS OR OTHER EXPERTISE REQUIRED. The contractor must have: Ph.D. in Biology, Life Sciences or a related discipline. Minimum of five (5) years of experience in biology or a related field. Strong background in genetics, molecular biology or a related discipline. Familiarity with age associated changes in immune system. Ability to work independently and think critically with skilled hands and sound judgment. Experience in genetics, molecular biology and the recent new advanced methods. Knowledge of proper laboratory disposal methods and safety procedures. PLEASE APPLY ONLINE Please visit www.kellycareernetwork.com to apply for this position. Due to the volume of inquiries, we regret that we cannot accept phone calls. Please also note that the phone number for our NIH branch is not listed.


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Mental Health Communications Editor

Date Posted:
3/10/2017

Kelly Government Solutions

MD

Mental Health Communications Editor/Coordinator ** NIH ** Rockville, MD ***Seeking candidates with neuroscience, psychology, and/or mental health background and experience to translate scientific and technical content into plain language for a variety of audiences. Please note this position requires hands-on experience with all aspects of science writing, editing, communications planning, and coordination*** Kelly Government Solutions is a strategic supplier and business partner to the federal government and its key suppliers. Through our partnership with the National Institutes of Health, Kelly Government Solutions offers administrative, IT, engineering, scientific, and healthcare professionals the opportunity to work with one of the most prestigious research organizations in the world. We are currently seeking a Mental Health Communications Editor/Coordinator to work with the National Institutes of Health in Rockville, MD. This is a long-term contract position which offers: - Competitive salary with comprehensive benefit package - Opportunity to work at NIH, world's foremost medical research center - Learn more about what Kelly can do for you at www.kellygovernmentsolutions.com TASKS/SERVICES: The contractor shall: (1) Develop strategic plans for science communications using state-of-the-art digital and traditional channels, including media, social media, web, video, mobile applications, online networks and other emerging platforms; develop plans to define clear goals, messages, target audiences, dissemination methods and metrics for monitoring implementation and/or impact. (2) Work with project teams and ensure that all communications activities outlined in strategic plans are tracked, coordinated and implemented, and that milestones are met and goals are achieved per established timelines. (3) Research and develop a variety of materials as background information to be used in preparing written and oral communication documents and presentations for the Institute Director and staff. (4) Work with Senior Content Strategist to define, implement and coordinate the overall NIMH enterprise content presentation strategy across all print and digital channels. (5) Oversee and manage web content, including accuracy and relevancy of posted scientific content and new web updates as directed; periodically review web site and make recommendations for improved user experience and information architecture. (6) Research, fact-check, edit, author and disseminate statements, press releases, reports, articles, speeches, presentations, and other materials about complex scientific information. (7) Provide support for media relations operations, including conducting background research on journalists, pitching reporters, writing talking points, clearing interview requests, gathering background materials, attending interviews, and analyzing coverage. (8) Serve as NIMH liaison to the Mental Health.gov editorial board by attending regularly scheduled meetings; provide guidance on content; draft and edit blogs for the site. (9) Develop the agendas, take minutes and track goals and action items for the Behavioral Health Coordinating Committee (BHCC) Communications Subcommittee and other ad hoc workgroups. (10) Design, produce, and evaluate information materials to reach national and international audiences through the media and intermediaries such as advocacy and professional organizations; disseminate this material to relevant audiences as directed. (11) Prepare major reports and documents for publication from development through concept clearance; edit and rewrite material prior to publication; coordinate with layout and graphic design team to ensure efficient and effective presentation. (12) Participate in the implementation, maintenance, enhancement and coordination of online systems and websites. (13) Oversee the identification and production of informational materials for NIMH website(s) and monitor the site(s) to ensure that posted information is accurate, timely and vetted according to required clearance procedures. (14) Work to establish and maintain contacts and working relationships with persons in professional and advocacy organizations, private industry and voluntary agencies to facilitate the nationwide dissemination of information and to gather information needed for the development of information materials and programs. (15) Build relationships with communications professionals, scientific staff, and program leaders across HHS, NIH Institutes and Centers, and other organizations to facilitate partnerships, information sharing and goal attainment. REQUIREMENTS: The contractor must have: (1) Ph. D. in Psychology, Neuroscience or a related discipline; three (3) years of specialized experience plus a Master’s degree is equivalent to a Ph.D. (2) Minimum of three (3) years of related experience, including federal government communications. (3) Experience in health communications, outreach and coordination. (4) Experience in project management. (5) Experience in developing strategic communications plans and communications program evaluation. (6) Experience writing and copy editing scientific content in plain language for a variety of audiences. (7) Extensive knowledge of web and social media platforms. (8) Experience in media relations, either as a public relations professional or a journalist. (9) Experience using multiple software programs, platforms and tools, including Microsoft Office Suite (MS Word, Excel, Outlook), Adobe, Acrobat Pro, SharePoint and GoToMeeting. (10) Strong communications skills, both oral and written. (11) Excellent analytical, organizational, and time management skills. PLEASE APPLY ONLINE Note that the phone number for our NIH branch is not listed. Due to the high volume of inquiries, we regret that we cannot accept phone calls. All qualified candidates will be contacted. Once you have applied online to the position, if you have specific questions, you may contact us at kellyrecruiter@mail.nih.gov


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Lecturer Biology

Date Posted:
3/10/2017

Oxfrod College

GA

Emory University's Oxford College seeks candidates for a Lecturer in Biology to begin August, 2017. The successful applicant will teach one lecture with laboratory course per semester in introductory biology and/or environmental science for majors and non-majors. The professional responsibilities are half teaching and half laboratory preparation for cell biology, genetics, and organismal biology.
REQUIRED: A minimum of a Masters degree in a biology sub-discipline with broad training in biology is required, along with at least one year of laboratory teaching experience in general biology.


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Scientific Annotator

Date Posted:
3/10/2017

MindSpec

VA

Position Description:
We are seeking talented and motivated individuals interested in working in a multi-disciplinary team. The positions offer an opportunity to work in the rapidly evolving area of multi-factorial disease biology in a flexible, dynamic research environment.
MindSpec, Inc. (http://www.mindspec.org/), is a nonprofit research organization that studies molecular causes of neurodevelopmental disorders such as autism using an integrated bioinformatics approach. MindSpec created the first genetic database for autism (AutDB), which is licensed to the Simons Foundation as SFARI Gene (https://gene.sfari.org/).

Qualifications:
Applicants must have an M.S. degree or higher in Genetics/Molecular Biology/Neurobiology or a related field with a strong knowledge of animal models of human disease. Applicants should also have excellent written and oral communication skills. Candidates who have research experience with zebrafish (Danio rerio) or Drosophila melanogaster are encouraged to apply.

Responsibilities:

Assess peer-reviewed scientific publications to determine their suitability in the context of given inclusion criteria.
Read and extract data from peer-reviewed scientific publications.
Use, evaluate and provide direction to develop data models and standards.
Take part in weekly meetings to help promote interpretative consistency between team members.
To Apply:
Please send cover letter and curriculum vitae to job@mindspec.org.


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Postdoc Neuromodulation

Date Posted:
3/10/2017

FDA

MD

Post-doctoral Fellow with FDA –Neuromodulation Job description A postdoctoral fellowship is available at Food and Drug Administration (FDA), Center for Devices and Radiological Health (CDRH), Office of Science and Engineering Laboratories (OSEL), Division of Biomedical Physics (DBP). The position is located at FDA White Oak main campus in Silver Spring, MD. Program participants will be paid a monthly stipend that is dependent on experience (starting from $79,720 per year). Funding is currently available for 1 year with the possibility of extension. The candidate must have received her/his most recent degree within 5 years prior to starting. The applicant has to be eligible to work in the U.S. Project description Neuromodulation is a growing field of therapy for its direct and focal effects on the neuronal circuits, which has the potential to be expanded for enhancing learning capabilities. However, the safety and efficacy of neuromodulation in healthy individuals and the potential sex differences needs further investigation. This project is aimed at understanding the safety and efficacy of neuromodulation using the in rodents, along with understanding of the potential sex difference. The outcome of this research would help answer some of the engineering and biological questions associated with neuromodulation and will help shape a modern regulatory landscape. Role of candidate The candidate will be involved in lab studies for evaluating neuromodulation in the autonomic nervous system. The role requires the candidate to perform rodent surgeries, electrical neural stimulation, electrophysiology, functional assays and immunohistochemistry. Activities may include experimental design, developing custom hardware and software setup, MATLAB scripts for data analysis and animal handling. The qualified candidate should have a Ph.D. in Biomedical Engineering, Neuroscience, Electrical Engineering or a related field. Preference will be given to applicants with some or all of the following skills and experience: • Engineering and scientific curiosity • Problem solving skills • Knowledge of neuroscience • Knowledge of endocrinology • Knowledge of immunology • Peripheral nerve surgery • Experience with telemetry implantation, data acquisition and analysis • Laboratory experience with animal handling and surgery • Electrophysiology - recording, stimulation and data analysis • Immunohistochemistry/Histology • Proficiency in MATLAB, Python, or at least one programming language The following knowledge/expertise is desired: • Experience with neuromodulation • Effective oral and written communication skills as demonstrated by presentation in international conferences and publications in peer reviewed journals How to apply To apply, please email Srikanth.Vasudevan@fda.hhs.gov including CV/resume with a cover letter in the body of the email and “Post-doctoral Fellow – Neuromodulation” in the subject line. The position is available immediately. Note that this appointment is offered through the CDRH Postgraduate Research Participation Program and is administered by the Oak Ridge Institute for Science and Education (ORISE). The program is open to all qualified U.S. and non-U.S citizens without regard to race, color, age religion, sex, national origin, physical or mental disability, or status as a Vietnam-era veteran or disabled veteran. The individual selected for appointments will not become employees of ORISE, ORAU, DOE, FDA, CDRH, or any other office or agency. Proof of health insurance is required for participation in this program. The appointment is full-time at FDA in the Silver Spring, MD. Company description The Food and Drug Administration (FDA) is an agency within the U.S. Department of Health and Human Services. FDA is responsible for protecting the public health by assuring the safety, efficacy and security of human and veterinary drugs, biological products, medical devices, our nation’s food supply, cosmetics, and products that emit radiation. This position is within the Center for Devices and Radiological Health (CDRH). CDRH seeks to assure that patients and providers have timely and continued access to safe, effective, and high-quality medical devices. CDRH facilitates medical device innovation by advancing regulatory science, providing industry with predictable, consistent, transparent, and efficient regulatory pathways, and assuring consumer confidence in devices marketed in the U.S. The Office of Science and Engineering Laboratories (OSEL) is the research arm of the Center for Devices and Radiological Health (CDRH). OSEL performs product testing; develops reliable standardized test methods for CDRH and industry use; performs anticipatory scientific investigations on emerging technologies; contributes laboratory data to national and international standards used in CDRH decision making; provides scientific and technical training for CDRH staff members; and maintains laboratory collaborations and relationships with scientific researchers in academia and other Federal laboratories. OSEL also coordinates and oversees CDRH’s activities that support the development of national and international standards.


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Patent Analyst Life Sciences

Date Posted:
3/9/2017

CPA Global

VA

Job description

Join the team! CPA Global seeks excited, inquisitive, and collegial individuals to join its Patent Search and Innovation Intelligence Services Team. Patent Analyst opportunities are available within two Patent Search divisions: the Patent Cooperation Treaty (PCT) and also the Commercial Search Group located in either Alexandria, VA or Southfield, MI offices. Remote employment is available in some circumstances.

 

 

 

For more information, see job descriptions below.

 

CPA Global is the world’s leading IP management and information Services Company with the insight, experience, and global expertise to create, protect, maintain, and maximize IP assets on a global scale.

 

As a business, CPA Global unlocks fresh thinking and inception of technology initiatives for clients throughout the world. Its teams of professionals synergize ideas and action, connect people with people and people with technology to ensure that individuals and organizations fulfil their potential.

 

CPA Global is a trusted business partner. It combines an entrepreneurial spirit with a “customers first” approach. The company works with honesty, integrity, and professionalism. CPA Global is responsive and responsible. These are qualities its clientele values and the company seeks to uphold.

 

CPA Global provides a casual and relaxed work environment focused on continuously exceeding its customers’ expectations. A hands-on training program focuses on developing knowledge and skills while allowing new employees to immediately produce results.

 

 

JOB DESCRIPTION

 

PCT Patent Analyst (Full Time)

  1. Assess the technology and disclosure to understand the technical nuances in preparation for performing the search to identify relevant references and documents.
  2. Maintain proficiency with commercial patent databases and other proprietary databases that disclose technical publications.
  3. Strategically perform searches and draft written opinions relating to patentability of PCT applications in the Analyst’s broad technical area.

 

 

 

 

 

 

Commercial Search Group (Full Time)

  1. Strategically perform searches relating to patentability (novelty), validity, freedom-to-operate and infringement in the computer science technical area.
  2. Perform Evidence-Of-Use studies by analyzing products currently used in the market that may be infringing on a patent of interest.
  3. Perform qualitative analysis of patents and patent portfolios from a legal, technical and business perspective.
  4. Conduct long-term patent landscape studies to identify trends in a technology field, deliver competitive intelligence and identify potential research and licensing opportunities.
  5. Maintain proficiency with commercial patent databases and other proprietary databases that disclose technical publications.
  6. Communicate effectively with customers in determining the scope of searches and draft informative reports that clarify and summarize search results.

 

 

 

 

REQUIREMENTS

 

Work Experience or Education required in one of the following areas:

 

  • Biotechnology (or Biology) – Cell and molecular biology, microbiology, human physiology, biochemistry, biophysics, stem cells, genetic engineering, pharmacology, biofuels, antibodies and immunology, vaccines, etc.

  • Life Sciences – Surgical equipment and procedures, medical devices, medical instrumentation, diagnostic equipment, medical imaging equipment, implantable devices, prosthesis, etc.

 

QUALIFICATIONS

 

 

  • (PCT Full Time Requirement ONLY) U.S. citizens or work eligible legal residents who have resided in the U.S. for at least the two previous years.
  • Bachelor’s Degree
  • 0-3 years previous patent examining or patent searching experience is strongly preferred, though not required.
  • In-depth knowledge of technical literature in the area of subject matter expertise.
  • Extreme attention to detail required.
  • Highly skilled developing a search methodology and in conducting searches.
  • Strong time management skills and dependable in completing quality projects against deadlines.
  • Excellent interpersonal, oral and written communication skills.

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Senior Field Applications Specialist Genomics 4 positions different locations

Date Posted:
3/9/2017

Covance

NC

Job description

Senior Field Applications Specialist Genomics

 

The Senior Field Applicantion Specialist is an expert in the the clinical application of Genomics and Biomarkers. The Field Application Specialist for Genomics supports clients in East Coast Mid-Atlantic territory and provides scientific expertise and guidance to Pharma and Biotech Clients and Business Development Directors during all stages of the sales process, with specific focus on the technical aspects of project planning and RFP support.

 

Key Job Duties Include

 

  • Works with Business Development Directors to ensure appropriate technical genomics strategy/solution is proposed to client. Monitor actions and results against client expectations.
  • Works directly with Operations, R&D, and Bioinformatics to maintain an advanced technical and operational understanding of Covance Drug Development service offerings
  • Actively prospect and leverage potential new business opportunities.
  • Work with management to identify target clients, markets and services that matches the company's capabilities.
  • Work across company's service lines and with sales teams to cross-promote and respond to RFPs as well as develop internal relationships needed to create solutions designed using multiple services.
  • Support sales and marketing services by attending, participating and speaking at trade shows and industry conferences.

     

Education/Qualifications - Bachelor's Degree Required.

 

  • Ph.D. or Master's degree in a scientific discipline (Molecular/Cellular Biology, Genomics) preferred.
  • Understanding of business and Industry trends and ability to interpret the trends relevant to the business.
  • Excellent analytical skills in assessing and interpreting customer technical requirements.
  • Excellent communication skills (written and verbal).
  • Ability to create and give technical oral presentations to large groups of scientists.
  • Must be self-directed and capable of prioritizing opportunities and performing multiple tasks.

     

Experience Experience

 

  • 7 years Experience and working knowledge of the principles of Translational Sciences, Genomics and Biomarkers with focus on Experience in clinical applications of the above sciences.

     

EEO Employer Covance is committed to diversity in the workplace and is an equal opportunity employer (Minority/Female/Individual with Disability/Veteran/Sexual Orientation/Gender Identity). Your confidentiality and privacy are important to us.

 

Raleigh-Durham, NC

 

Raleigh-Durham, North Carolina

Seniority Level

Entry level

Industry

  • Biotechnology
  • Hospital & Health Care
  • Pharmaceuticals

Employment Type

Full-time

Job Functions

  • Research
  • Analyst
  • Information Technology

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Scientist/Senior Scientist

Date Posted:
3/9/2017

Cellular Dynamics International

WI

Company Description

We develop and manufacture fully functioning human cells in industrial quantities to precise specifications. Our proprietary iCell Operating System (iCell O/S) includes true human cells in multiple cell types (iCell products), human induced pluripotent stem cells (iPSCs) and custom iPSCs and iCell products (MyCell products).

Our iCell O/S products provide standardized, easy-to-use, cost-effective access to the human cell, the smallest fully functioning operating unit of human biology. Customers use our iCell O/S products, among other purposes, for drug discovery and screening; to test the safety and efficacy of their small molecule and biologic drug candidates; for stem cell banking; and in researching cellular therapeutics.

Job Description

Cellular Dynamics, a FujiFilm Company, is currently hiring for a Scientist/Senior Scientist position at our Madison, WI location. This position requires a self-motivated individual with demonstrated proficiency in mammalian cell culture and stem cell biology (cell culture and differentiation) who can contribute to our efforts to efficiently manufacture differentiated human cell types from human induced pluripotent stem cells.

Qualifications

Qualifications

Skills and Responsibilities:

• Mammalian cell culture including human induced pluripotent stem cells and differentiated cells.
• Differentiation of stem cells into multiple differentiated cell lineages.
• Cell culture medium production and optimization.
• Quantitative biochemical, cell, and molecular biology analyses, such as gene and protein expression, immunohistochemistry and flow cytometry,
• Functional assessment of differentiated cell function using cell specific assays.
• Design, planning and efficient execution of experiments that meet scientific goals and timelines.
• Effective written and oral communication of experimental design, rationale, and results to peers and management.
• Good documentation practices when documenting ideas, recording data, and completing records.
• Effective drafting of standard operating procedures.

Essential Job Requirements:
• Relevant experience or an advanced degree (M.S. or Ph.D.) in stem cell biology, cell biology, developmental biology, biomedical engineering or a closely related field.
• Proficiency in pluripotent stem cell culture and differentiation of pluripotent stem cells is required.
• Knowledge of general developmental biology and bioinformatics principles is desirable.
• Possess initiative, ability to multi-task and a desire to acquire new technical skills.
• Proficiency in independent experimental design, planning and execution.
• Experience operating in a team-based multidisciplinary environment is desirable.
• Excellent record keeping and organizational skills.
• Excellent oral and written communications skills.
• Flexible work schedule, weekend work is required.
• Proficient use of software such as MS Office, Prism and various flow cytometry programs.
• Project planning and experience operating in a team-based multidisciplinary environment is desirable.
• Industry and personnel management experience is desirable

Additional Information

Cellular Dynamics International Inc. is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, age, protected veteran status or status as an individual with a disability. All qualified applicants will not be discriminated against on the basis of a disability.


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Field Application Scientist

Date Posted:
3/9/2017

Cellular Dynamics International

MA


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Field Application Scientist

Date Posted:
3/9/2017

Quanterix

MA

Job description

Quanterix is an exciting early-stage commercial company currently developing a transformational platform that combines proprietary single-molecule sensitivity, multiplexing and full automation with its revolutionary Single Molecule Array (Simoa) technology. Located in Lexington, MA, the company has launched an instrument for the life sciences research industry. With unprecedented sensitivity, precision, multiplex capabilities, and full automation, Simoa offers significant benefits for both research and clinical testing applications. Quanterix is looking to hire an experienced Field Applications Scientist currently located in the Boston area to support the market development of its Simoa HD-1 Analyzer.

 

This critical role, first and foremost, will work very closely with the Quanterix Account Managers to support the sales process where greater technical depth is required, such as presentations at customer sites and at conferences. This person is also responsible for ensuring that customers are successful once they start using Simoa through effective training and support. The Field Applications Scientist will work closely with and support the Field Service organization to help customers quickly resolve any technical or operational issues. Finally, this individual is expected to work closely with the internal Assay Development and R&D teams to help develop new customer-driven applications.

 

Qualifications/Requirements

 

    • Masters Degree or higher in biology, chemistry, biochemistry or related field, a PhD. is preferred
    • 5+ years of customer-facing experience in applications, technical sales support, or related functions
    • Strong understanding of, and experience with, current immunoassay platforms and technology
    • Experience supporting novel, ground-breaking technologies preferable
    • Equally comfortable in front of customer as in the lab
    • Excellent technical communication and writing skills
    • Proficiency in spoken and written English
    • Team spirit, positive attitude, strong work ethic.

 

About Quanterix

 

Quanterix Corporation is a privately held, dynamic and growing company located in Lexington, Massachusetts. We are building a team of best-in-class scientists, engineers and business professionals that thrive in a collaborative high-energy entrepreneurial environment. We believe that the commercialization of an enabling technology with the potential to revolutionize life science research and clinical diagnostics will require the very best people working together and exchanging ideas while sharing a commitment to innovation. Quanterix is an Equal Opportunity Employer that offers a competitive and comprehensive employee benefits package, including health, dental, life insurance, a flexible spending plan, paid vacation, stock options and a 401(k) investment plan.

Seniority Level

Associate

Industry

  • Biotechnology

Employment Type

Full-time

Job Functions

  • Research
  • Analyst
  • Information Technology

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Field Application Scientist

Date Posted:
3/9/2017

Nanostring

CA

Job Summary

 

The Field Application Scientist works with the Regional Account Managers to ensure customer adoption, success, acceptance, and driving additional revenue growth with the technologies offered by NanoString Technologies.

 

Territory: Los Angeles, California and a variety of Mountain and South Western States

 

Essential Functions

 

    • In partnership with the Regional Account Managers (RAMs), identify sales opportunities through identification and relationship building with P.I.s in positioning the power and utility of NanoString's technologies for their research or developmental efforts
    • In pre-sales environments, conduct seminars, give technical sales presentations, and collaborate with P.I.s in the building and designing of projects to either support the purchasing of an nCounter system or through partnership with an institutional/regional core lab (if available)
    • In post-sales environments, train new customers on the system, partner with clients in project scoping and design elements to increase CodeSet adoption and usage, conduct data analysis sessions with regional customers to accelerate full adoption of the technology, provide on-site troubleshooting as needed, and participate in the cultivation of revenue generating post-sales support and consultative opportunities
    • Partner closely with the Regional Account Managers in the positioning of new technologies as they are released. Develop partnerships that may contribute to early access programs for these technologies
    • Collaborate with the in-house Technical Services team and other Field Applications Scientists in the post-sales support of customers and their applications
    • Contribute to the development and refinement of the processes and materials used by the global support teams in the information and tools needed by the global team in advancing the needs of our customers
    • Be trained on NanoString's Diagnostic product lines to provide triage support as well as implementation support in the Western U.S. (approx. 10%)

 

Requirements

 

  • Requires a Ph.D. in a molecular biology / biochemistry related field
  • At least 3 years of relevant practical laboratory experience and technical expertise
  • Focused research/academic experience in Immunology and/or Immuno-oncology highly preferred
  • Experience and/or deep understanding of the following areas highly preferred: Gene Expression analysis, miRNA, Copy Number Variation, IHC, Flow Cytometry, RNASeq, QPCR, and Protein Expression assays
  • Experience with biostatistics and computational data analysis is strongly preferred
  • Requires excellent communication skills, verbal and written
  • Ability to travel up to 75%
  • Experience in a technical customer support role desirable
  • Commercial experience desirable
  • Strong working knowledge of the sales process as well as a good understanding of the Miller Heiman selling process and terminology preferred but not required

Job posted by

Maya Skolnik

Recruiting & Talent Manager at NanoString Technologies, Inc.

Job Poster Location

Greater Seattle Area

Premium

Seniority Level

Not Applicable

Industry

  • Biotechnology
  • Research
  • Medical Devices

Employment Type

Full-time

Job Functions

  • Research
  • Analyst
  • Information Technology

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Field Application Scientist

Date Posted:
3/9/2017

MSD

PA

Job description

Field Application Scientist II

 

POSITION SUMMARY:

 

Provide comprehensive scientific consultation to support account management in tandem with the internal sales organization. Consult is provided in a highly personalized and customized client-centric approach at the individual customer site or remotely through phone and e-mail communications. The incumbent should demonstrate a strong desire to succeed in a competitive commercial environment and will carry out evaluations at prospect sites for new instrument opportunities, support new and existing customers in the use of MSD kitted assays and in the development of new assays in a multidisciplinary setting.

 

This position may mentor junior level staff and manage more complex operations and/or larger territory and strategic accounts than Field Application Scientist. The incumbent should be based in Philadelphia.

 

DUTIES AND RESPONSIBILITIES:

 

  • Educate, train and support new/existing customers on MSD instrumentation and data analysis.

 

  • Train customers on the use of MSD assays, instrumentation and software
  • Assist existing customers with assay troubleshooting and data analysis
  • Provide support for customers wishing to develop their own assays on the MSD platform
  • May include but not be limited to inflammation, oncology, metabolic disorders, neuroscience, immunogenicity, PK, toxicology, bioproduction
  • Effective and timely response time to inquiries
  • Attend scientific meetings, conferences and trade shows, provide feedback and reports
  • Travel 30 to 50% of the time; able to work at customer sites four days a week
  • Work as part of a team and integrate information between sales and marketing groups to provide resolution of customer issues and expand the customer base through scientific networking.

 

  • Integrate with account managers in the strategic selling process to grow instrument and consumable sales in the territory.
  • Present scientific seminars to prospects
  • Create reports and presentations from assay development visits and new evaluations
  • Provide feedback from the field to other team members, account managers and internal groups
  • Document activities and customer interactions in the CRM software (SalesForce.com)
  • Specific duties may vary depending upon departmental requirements.

 

EXPERIENCE AND QUALIFICATIONS:

  • Ph.D. in Life Sciences or related area required
    • Master’s degree in related field with equivalent experience considered
  • At least 7-10 years of experience in a field application or scientific support position required
  • 3-5 years of hands on experience working in molecular biology lab, clinical lab, discovery lab or biochemistry in a research or clinical setting is required
  • Experience in protein biochemistry required
  • Experience with immunoassays required
  • May supervise others’ work and/or mentor other Field Application Scientists

 

 

 

KNOWLEDGE, SKILLS AND ABILITIES:

  • Demonstrate superior competency in analytical skills and strong scientific fundamentals
    • Logical problem solving and demonstrated ability to organize and move project tasks forward in an orderly and structured fashion
  • Display a thorough understanding of the principles of immunoassays, their development and their applicability in different research fields
    • Independently execute assay and reagent troubleshooting, optimization and validation experiments
  • Excellent oral, written communication and interpersonal skills as a core competency to include presentation and training styles
    • Effectively communicate issues/problems and results that impact timelines, accuracy and reliability of laboratory data
  • Demonstrate effective time and project management and competency in a customer-centric environment
  • A wide degree of creativity and latitude is expected including the ability to multi-task and work productively in a demanding research environment with changing priorities

 

 

 

PHYSICAL DEMANDS:

This position requires the ability to communicate and exchange information, utilize equipment necessary to perform the job, and move about the office and travel on a regular basis.

 

 

 

WORK ENVIRONMENT:

This position may require up to 30-50% travel within the designated territory, being present at customer sites up to four/five days a week. Candidates should also expect to spend time in a laboratory environment occasionally working with blood products and various allergens


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Expert Scientist Molecular Analystics

Date Posted:
3/9/2017

GSK

MD

Basic Qualifications

 

  • MSc plus at least 10 years of experience in an industrial, academic, or government laboratory setting

     

Preferred Qualifications

 

  • PhD plus 3 years of experience in an industrial, academic, or government laboratory setting
  • Excellent Publication Records

     

Details

 

Job Purpose:

 

Key member with expertise in Next Generation Sequencing (NGS) and bioinformatics related to the area of infectious disease research, in diverse team of vaccine scientists, to design, characterize, optimize, evaluate and select vaccine candidates, and support platform technology development.

 

Key Responsibilities

 

  • Demonstrates a detailed fundamental knowledge in NGS and bioinformatics, as they apply to vaccine discovery and development
  • Have practical knowledge of multiple NGS platforms, e.g. Illumina, Pac Bio, and the analysis of NGS data sets, particularly related to infectious agents
  • Subject matter expert in most relevant fields involving the team
  • Has transversal overview of all related activities within the department
  • Leads vaccine development-related scientific investigations, and publishes the work in scientific journals and patent filings
  • Executes a wide range of experiments/technical studies/tasks independently based on protocol
  • Develop and executes new methods and protocols and proactively incorporates new technology or techniques into practice with minimal supervision
  • Performs complex data management tasks with minimal supervision
  • Interprets results and communicates to the supervisor and designs next logical step of experiments based on interpretation of results
  • Prepares oral or written summaries of results with interpretation for projects/programs
  • Independently writes specific technical sections of internal, external reports, and scientific papers

     

Contact Information

 

You may apply for this position online by selecting the Apply now button.

 

If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK HR Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).GSK is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.

 

Important notice to Employment businesses/ Agencies

 

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

 

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit GSK’s Transparency Reporting For the Record site.


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Bioinformaticist Scientist, Cancer

Date Posted:
3/9/2017

Qiagen

NC

QIAGEN/Omicsoft is seeking a highly motivated and experienced bioinformatics scientist who can contribute his/her own unique perspectives to our collective understanding of genomics data for biomedical researches. The primary responsibility is to understand genomics data from varied disease areas, and to develop data analysis plans/pipelines to generate biological meaningful results and visualizations. By collaboratively working with internal research and development team, the successful candidate will integrate acquired knowledge into our efforts to provide great genomics knowledge products to our clients.

 

 

 

Job location: Cary, NC or Redwood City, CA

 

 

 

Key Responsibilities

  • Collaborate with colleagues to understand our clients’ interests and biological questions
  • Develop data analysis strategies and plans to address clients’ need.
  • Perform data analysis on genomics data sets using Omicsoft products as well as other Bioinformatics and statistical tools
  • Prepare presentations to summarize findings and train customers
  • Training customers to explore data and answer biological questions using Omicsoft software and Lands
  • Other data analysis and bioinformatics researches funded by clients

 

 

 

Basic Qualification

  • PhD in Bioinformatics, Computational Biology or related fields
  • Research experience in the fields of genomics and NGS data analysis
  • Understanding of basic biology and cancer biology
  • Experience with R, Python or Java, Unix/Linux/HPC
  • Enjoys working in collaborative team environment
  • Strong written and oral communication skills to present scientific data and methods

 

 

 

Preferred Qualifications

  • Experience in cancer research and drug development is a plus

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Prinicple Scientist Protein

Date Posted:
3/9/2017

Alkermes

MA

Alkermes plc is a fully integrated, global biopharmaceutical company developing innovative medicines for the treatment of central nervous system (CNS) diseases. The company has a diversified commercial product portfolio and a substantial clinical pipeline of product candidates for chronic diseases that include schizophrenia, depression, addiction and multiple sclerosis. Headquartered in Dublin, Ireland, Alkermes plc has an R&D center in Waltham, Massachusetts; a research and manufacturing facility in Athlone, Ireland; and a manufacturing facility in Wilmington, Ohio. For more information, please visit Alkermes’ website at www.alkermes.com .

 

Position Description: Alkermes is searching for a highly talented scientist for a position primarily responsible for designing our next generation of protein therapeutics. The ideal candidate will take a leading role in ideation and engineering of new proprietary fusion proteins, additionally executing and guiding in vitro studies through proof-of-principle.

 

Key Duties

 

    • Primary responsibilities for designing our next generation of protein therapeutics, including but not limited to expression, purification, biophysical characterization and cell-based activity assays

       

    • Prosecute novel therapeutic proteins to demonstrate proof-of-principle using in-house capabilities as well as external resources (CROs)

       

    • Participate in advancing Alkermes pipeline and capabilities in protein therapeutics

       

    • Support IP protection and publications

       

 

Technical Skills

 

    • Protein design and engineering

       

    • In-depth understanding of protein structure-function, with knowledge in modeling

       

    • Bacterial and mammalian protein expression (including transient transfection)

       

    • Protein purification (experience with AKTA FPLC purification systems required, HPLC/UPLC a strong plus)

       

    • Protein characterization techniques, including chromatography, label-free technologies (e.g. Biacore or Octet), and mass spectrometry

       

    • Other analytical techniques including SDS-PAGE, flow cytometry and immunoassays (ELISA and/or MSD) analysis

       

    • Experience in standard molecular and cell biology techniques (bacterial and mammalian cell culture)

       

    • Assay development and execution (in vitro, cell-based, ex vivo) with expertise in multiple assay formats (e.g. fluorescence, luminescence, FRET, FP, high content imaging)

       

    • Highly effective written and verbal communication skills

       

 

Personal Skills

 

    • Ability to rapidly identify, learn and apply techniques

       

    • Ability to independently drive projects

       

    • Ability to multi-task, and independently design, execute experiments

       

    • Sense of urgency (self-motivation)

       

    • Scientific creativity

       

    • Flexibility to learn and take on new tasks according to changes in priority

       

    • Strong interdisciplinary communication skills

       

 

Minimum Education And Experience

 

    • PhD in a relevant scientific discipline (cell biology, biochemistry, biophysics or related discipline) with > 5 years experience in the biotechnology/pharmaceutical industry setting required

       

 

Alkermes, Inc. is an equal employment opportunity employer and does not discriminate against any applicant because of race, color, religion, sex, sexual orientation, gender expression and identity , national origin, ancestry, age, mental and physical disability, genetic information, any veteran status, military status or application for military service, or membership in any other category protected under applicable law.


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Postdoctoral Fellow Computational Microbiologist

Date Posted:
3/9/2017

Henry M Jackson Foundation

MD

The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HJF) is seeking a Postdoctoral Fellow II to support the Enteric Diseases Group in the Department of Preventative Medicine and Biostatistics at the Uniformed Services University (USU) in Bethesda, Maryland. HJF provides scientific, technical and programmatic support services to USU. Responsible for initiating and carrying out research projects in collaboration with Drs. David Tribble and Mark Riddle.

 

 

 

 

Responsibilities:

1. Assists in designing, developing, executing, and implementing scientific research and/or development.

2. Investigates the feasibility of applying a wide variety of scientific principles and theories to potential inventions and products.

3. Uses appropriate software packages to analyze whole genome sequencing, functional gene array, and proteome array data from high throughput technologies.

4. Collects and handles data and keeps detailed records of experiments.

5. Assists with the preparation of data for presentations at scientific meetings and for publication in journals.

6. Assists with training staff as needed.

7. Performs other duties as assigned.

 

 

 

Required Knowledge, Skills, and Abilities: Knowledge of biological network analysis; Proficiency in R, BioPerl, UNIX, and other related languages; Understanding of host:pathogen interactions

 

 

 

Minimum Education/Training Requirements: PhD in computational biology, biostatistics, computational science, microbiology, or related field

 

 

 

Minimum Experience: 2-4 years

 

 

 

Physical Capabilities: Long periods of sitting; intricate work with hands

 

 

 

Supervisory Responsibilities/Controls: Provide guidance to laboratory staff

 

 

 

Work Environment: Office environment; may require working evenings and weekends

 

 

 

HJF is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or protected veteran status.


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Postdoc Fellow

Date Posted:
3/9/2017

Geneva Foundation

MA

Overview:

 

 

 

 

 

The Postdoctoral Fellow I provides assistance to the Principal Investigator, Co-Investigators, and Research Staff. S/he ensures protocol adherence, monitoring visits, overseeing regulatory and administrative details, data management assistance and project close-out support is provided.

 

US Citizenship Required

 

 

 

Responsibilities:

 

 

 

 

 

  • Collaborate and assist the Principle Investigator, Co-Investigators and research team in the performance the research study
  • Contribute to the drafting and submitting of abstracts, manuscripts and reports for dissemination
  • Prepare progress reports on research as required
  • Analyze and write-up data
  • Present complex information effectively to a range of audiences
  • Provide data management assistance
  • Provide project close-out support
  • Maintain and promote Geneva’s core values of Integrity, Superior Service to Customers, Quality, Teamwork, Innovation, and Respect for All
  • Possess a working knowledge of The Geneva Foundation’s Employee Handbook, User’s Guide and Standard Operating Procedures (SOPs) as applicable
  • Remain accessible and accountable at all times during work hours and collects messages at least twice daily
  • Return telephone messages within 24 hours of receipt; return email messages in a timely manner as appropriate
  • Comply with the dress code of The Geneva Foundation and assigned duty station
  • Promote positive, professional relationships with co-workers and The Geneva Foundation
  • Maintain and update files of all applicable regulatory documentation for IACUC or IRB (including protocols, approvals, amendments, modifications, etc.) as well as any communications with the sponsor or any other Federal or regulatory office (including prior approvals, change in scope, etc.)

 

 

 

Qualifications:

 

 

 

 

 

  • PhD or MD required
  • Biomedical , Mechanical , Bioengineering, Electrical engineer or similar degree
  • 1-2 years medical research project management experience strongly desired, preferably with Department of Defense
  • Knowledge of military system, preferred
  • Demonstrate competence in oral and written communication
  • Must be organized, attentive to detail, and possess a positive, friendly and professional demeanor
  • Ability to be flexible with changing priorities and available to interact with employees, clients and sponsors of all levels
  • Ability to exercise independent judgment in fast-paced, high-pressured environment with strict deadlines and to manage multiple projects
  • Computer skills including at least intermediate level experience with Excel and other Microsoft Office Software
  • Cell and/or tissue culture experience required
  • Experienced with 3D fluorescent confocal microscopy and electrospinning
  • Experienced with 3D bioprinting
  • Experience with micro fabrication
  • Experience with mechanical systems
  • Experience with materials testing
  • Experience in a wet lab environment
  • Knowledge of one or more of the following or similar software: LabView MATLAB Solidworks/CAD Cadence

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pharmacovigilence Scientist

Date Posted:
3/9/2017

Proctor and Gamble

OH

The Research and Development Division (R&D) is responsible for building and protecting P&G business and corporate reputation by ensuring our ingredients, products and packages are safe and viewed as such, in regulatory compliance and delivering against our global sustainability vision. As a member of the team, you will be responsibility to manage, monitor and understand in-market product safety for P&G products sold worldwide.

 

The Ideal Candidate

 

As The Pharmacovigilance Scientist, You Will Have Responsibility To Manage, Monitor And Understand In-market Product Safety For P&G Products Sold Worldwide In Order To

 

I. Ensure consumer safety and regulatory compliance

 

II. Enhance existing systems and improve current work processes for safety surveillance and

 

III. Analyze health related consumer complaints for signal detection and continual product improvement.

 

You will be the subject matter expert within Global Safety Surveillance & Analysis with respect to the in-market safety profile, symptom profile and special issues for your assigned product categories. You will obtain a good understanding of relevant regulations and will ensure that all regulatory submissions are processed in accordance with applicable regulations and requirements. You will be the product vigilance single point of contact for other P&G functions. You will be responsible for signal detection and signal management activities associated with your assigned product categories.

 

Qualifications

 

Qualifications and skills required are as follows:

 

  • An advanced degree in either a health care profession (e.g. Pharm. D., M.D.) or life science (PhD).
  • Good collaboration skills and experience in establishing and maintaining working relationships.
  • Excellent written and oral communication skills in English with an emphasis on communication of human health relevance, safety and clinical information. Experience with external communications to regulatory authorities and industry groups would be beneficial but is not essential.
  • Excellent organization skills, an attention to detail and an ability to manage complex systems.
  • Experience with databases, data reporting tools and statistical analysis would be beneficial.

     

Previous experience in product vigilance is desirable but not essential. What matters is your enthusiasm, your willingness to learn and your collaborative and interpersonal skills. There is always plenty of help, support, coaching and training available from colleagues, with formal training being tailored to your needs and interests.

 

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, protected veteran status, disability status, age, sexual orientation, gender identity and expression, marital status, citizenship, HIV/AIDS status or any other legally protected factor.

 

Immigration sponsorship is not available for this position. Applicants for U.S. based positions are generally required to be eligible to work in the U.S. without the need for current or future sponsorship. Except in rare situations based on Procter & Gamble's sole discretion. Procter & Gamble does not sponsor candidates for permanent residency. Any exceptions would be based on the Company's specific business needs at the time and place of recruitment as well as the particular qualifications of the individual.

 

Procter & Gamble participates in e-verify as required by law.

 

Qualified individuals will not be disadvantaged based on being unemployed.

 

**Please include your resume and a brief summary of your research in the resume text field (maximum characters 64,000).**

 

Job IDRND00003486


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PhD Scientist, Immunology

Date Posted:
3/9/2017

Vendata

MA

The Ph.D. will conduct in-vivo studies designed to assess the ability of commensal bacteria to induce immune responses in germ-free and conventional mice. The principal activities of this role will be to develop assays to evaluate molecular and cellular pathways of host-microbe interactions, execute high-throughput screens, and perform in vivoexperimental procedures using mouse models. Responsibilities also include the culturing and phenotypic characterization of human and murine primary immune cells. The job title and level will correspond to the experience and skills of the selected candidate.

Qualifications

  • Ph.D. in immunology with a focus on mucosal immunotherapy and the role of the microbiome. Research experience in autoimmunity and/or gastrointestinal inflammatory diseases a plus
  • Expertise in the use of germ -free mice as well as animal models of gut associated autoimmunity and inflammation desired
  • Previous research experience and basic immunological techniques (flow cytometry, ELISA, cell culture and phenotypic characterization of primary immune cells) as well as molecular biology methods (RNA and DNA isolation and analysis, PCR)
  • Highly motivated and organized individual with excellent communication skills
  • Strong publication record
  • Team player, able to work well in a group setting as well as independently in a fast paced environment.
  • General understanding of the field of the human microbiome is preferred but not required.

Job posted by

Spencer Ball 2nd

Vice President Talent Acquisition at PureTech Health

Job Poster Location

Greater Boston Area

Premium

Seniority Level

Associate

Industry

  • Biotechnology

Employment Type

Full-time

Job Functions

  • Science
  • Research

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Product Support Specialist

Date Posted:
3/9/2017

Illumina

MA

Do you want to make a difference? Illumina’s mission is to improve human health by unlocking the power of the genome. If that inspires you, let’s talk. We’ve built a culture fueled by innovation, collaboration and openness, and established ourselves as the global leader in DNA sequencing and array-based technologies. Our people and our technology change lives by driving advancements in life sciences, oncology, reproductive health, agriculture and other emerging markets. We are deeply passionate about what we do, because we know that our work has the power to improve lives.
We’re an established company with a track record of phenomenal growth. Our revenue grew from $10 million in 2002 to approximately $2.2 billion in 2015. Our growth isn’t just revenue, we’ve been hiring the best and the brightest. Perhaps that’s why MIT has ranked Illumina near the top of its World’s Smartest Companies list three years running, including #1 in 2014. If you thrive in a brilliant, fast-paced, and mission-driven environment, Illumina is the place for you – imagine the possibilities.
Position Summary
As a Product Support Scientist; you will play a key role enhancing Illumina’s unparalleled customer support by performing remote troubleshooting on complex application and consumable issues with front-line support staff. You will also monitor complaint trends and advocate for product improvements that impact customer satisfaction and field implementation. Responsibilities will also include develop, author, and dissemination of technical updates and field bulletins to the global support and Customer Solutions organization. A successful candidate will have demonstrated experience of inter-departmental work experience and familiarity with CRM and ERP systems. Candidates will receive extensive experience with Illumina’s cutting-edge products.
All About You
Responsibilities:
Effective communication among peers and colleagues across global regions and corporate structure
Monitor intake complaints related to product design, robustness and customer satisfaction issues
Assist Technical Support and Field Service & Support staff with remote resolution of complex support cases and travel to customer sites to assist with resolution of complex issues as needed
Elevate complex support issues through appropriate channels and participate in multidisciplinary teams to speed resolution
Coordinate sustaining product releases with minimal assistance
Update, edit and author technical documentation and process in conjunction with key business members and teams
Partner with departmental groups on new product launches and assist with preparation and training of front-line support staff
Moderate travel (up to 15%)
Requirements:
At least 5 years of commercial biotech/biomedical science industry experience preferred
Prior experience in an in-house or field support role preferred
Strong analytical, problem solving, and interpersonal skills
Clear vision and commitment to providing outstanding customer service
Working experience with SFDC and/or SAP; and familiarity with quality systems
Education
PhD, MS, or BS in Molecular Biology or Life Sciences related degree; or related work experience
Illumina believes that everyone has the ability to make an impact, and we are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information.
Seniority Level
Not Applicable

Industry
Biotechnology Research Medical Devices
Employment Type
Full-time

Job Functions
Information Technology


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Senior Scientist Immunometabolism

Date Posted:
3/9/2017

Pfizer

MA

A career at Pfizer offers opportunity, ownership and impact. All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.

 

 

Role Description

 

Pfizer I&I department aims to develop novel therapeutics in treating chronic inflammatory diseases, in particular RA, IBD and SLE. Emerging data suggest that dysregulated metabolism of immune cells underlies the pathogenesis of these diseases. This position has been created to support elucidation of key metabolic processes that drive inflammatory pathogenesis and to identify novel targets that can be targeted to develop next-generation of therapies. This person will apply state of the art RNA interference and genome editing techniques to manipulate metabolic pathways in both adaptive and innate immune cells and determine the impact on their in vitro and in vivo functions. This person will work as part of a team to drive the in-depth understanding of biology, validation of target and delivery of novel therapeutics as ultimate goal.

 

 

Responsibilities

 

*Design and perform experimental studies to understand the biology relevant to disease to enable target/pathway validation *Support the design and development of in vitro experiments using mouse and human immune cells. *Establish essential phenotypic assays, applying CRISPr/Cas9 and/or virally mediated RNAi and in vitro/in vivo models suitable for dissecting disease biology, screening and testing compounds or biologics *Work with project team as a key biologist to coordinate and perform biology related work for the development of novel therapeutics *Identify and evaluate novel therapeutic targets in collaboration with other colleagues including biologists, geneticists, chemists as well as by actively engaging external collaboration

 

 

Qualifications

 

* PhD plus 3-5 post-graduate years relevant academic/industrial experience in the area of immunology,molecular/cell biology, biochemistry, or other related biology area.

 

 

 

* Successful candidates would be able to demonstrate effective communication skills, independent thinking as well as a publication record

 

 

 

* Experience in isolating and culturing primary immune cells: Expertise in T cell differentiation, CFSE-based proliferation assays, co-culture assays, regulatory T cell suppression assays and ability to design and conduct antigen-specific stimulation assays such as ELISPOT is highly desired.

 

 

 

* In addition to routine immunological assays such as ELISA, intracellular staining, FACS, qRT-PCR etc. experience in metabolism-related assays such as bioenergetics profiling using the Seahorse analyzer would be highly valued.

 

 

 

* Experience with recombinant DNA transfections, lentiviral / retroviral transductions would be a definite plus.

 

 

 

* Ability to work with large numbers of samples obtained from in vivo studies: Isolation of cells from lymphatic and peripheral tissues, analyses of inflammatory mediators in serum / plasma, ex-vivo FACS based phenotypic and functional assays.

 

 

 

* Competent user of relevant software packages supporting the manipulation of data and experimental design - PRISM, Cloner, Office, etc

 

 

EEO & Employment Eligibility

 

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.


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Postdoctoral Fellow

Date Posted:
3/9/2017

Genentech

CA

The Position

 

A postdoctoral position is available for a candidate interested in pursuing genomics research. The successful candidate will have the opportunity to use bioinformatics, in vitro and in vivo approaches to dissect genetic alterations in cancer. You will have an opportunity to analyze large data sets from nextgen sequencing, CRISPR/CAS9 technologies, mass spectrometry, knock-out and/or transgenic mouse models to understand gene function and signaling. Those with experience in these areas and experience with large-scale genomics data are strongly encouraged to apply.

 

For recent publication from the group refer to Nat Genet. 2016 48:407-16, Nat Biotechnol. 2015 33:306-12, and Nat Genet. 2015 47:13-21

 

Information about the postdoctoral program at Genentech can be found at http://www.gene.com/careers/academic-programs/postdocs.

 

For more information on Somasekar Seshagiri lab, please visit: https://www.gene.com/scientists/our-scientists/somasekar-seshagiri

 

Who You Are

 

A Ph.D with a strong background in bioinformatics, molecular biology or cellular biology is required. Candidates for this position must have high quality first author publications from their Ph. D. work.

  •  

Who We Are

 

 

A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

 

The next step is yours. To apply today, click on the "Apply online" button below.

 

Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our


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Postdoc Cancer Research

Date Posted:
3/9/2017

Cold Spring Harbor

NY

Job description

Requisition Details

 

Requisition Information

 

Requisition Title Postdoctoral Cancer Research Training Opportunity

 

Requisition Number 01355-R

 

Opening Information

 

Job Status Full Time

 

Position Category Post Doctoral

 

Education Required Graduate Degree

 

Position Description

 

Experience Required Less than 1 year

 

POSTDOCTORAL CANCER RESEARCH TRAINING OPPORTUNITY AVAILABLE COLD SPRING HARBOR LABORATORY

 

Located on the North Shore of Long Island and celebrating its 125th year anniversary, Cold Spring Harbor Laboratory ( CSHL ), has a distinguished record of excellence in biological research and education. CSHL’s NCI Designated Cancer Center has been an integral part of the Laboratory’s research mission since 1987. We have a postdoctoral training position available in CSHL’s Cancer Gene Discovery and Cancer Biology Postdoctoral Research Training Program, supported by the National Cancer institute of the National Institutes of Health ( NIH ).

 

Cancer research at CSHL is devoted to understanding the fundamental biology of human cancer in order to improve the diagnosis and treatment of many major forms of the disease. The primary goal of the training program is to prepare the next generation of cancer biologists to pursue independent research that integrates cancer gene discovery with functional biology in order to facilitate the development of novel cancer therapeutic, diagnostic and/or preventive strategies. The program benefits from a collaborative and multidisciplinary research environment, an internal Executive Committee that includes trainee representation, and an independent External Advisory Board.

 

Features of the three-year research training program include courses, structured career development activities, research seminars, teaching opportunities, and hands-on research training experiences in laboratories affiliated with the CSHL Cancer Center. Postdoctoral trainees benefit from a small faculty to trainee ratio, an on-site internationally renowned scientific Meetings and Courses Program, and newly expanded state-of-the-art cancer research facilities.

 

Cancer research opportunities span four highly integrated areas that include cancer; 1) Genetics – sequencing, genetic models, chromosome engineering; CRISPR /Cas9, single cell analysis; 2) Gene Regulation and Cell Proliferation – splicing, replication, epigenetics, nuclear structure, tumor growth and metastasis; 3) Signal Transduction and Human Cancer Impact – drug sensitivity and resistance, clinical correlates, disease status and outcomes; and 4) Quantitative Biology – population genetics, genome structure and evolution.

 

Position Requirements

 

Eligibility-

 

By The Time Of Appointment, Applicants Must

 

 

  • Be interested in preparing for a career as an independent cancer researcher
  • Have received a Ph.D., M.D., or comparable doctoral degree from an accredited domestic or foreign institution
  • Be within the first three years of postdoctoral training
  • Be a citizen, or a non-citizen national of the U. S. or have been lawfully admitted for permanent residence

     

(eligibility requirement of the National Institutes of Health ( NIH ), Ruth L. Kirschstein, National Research Service Award- NRSA )

 

 

How To Apply

 

Please apply as soon as possible by sending a letter of introduction, along with a curriculum vitae and the names of three individuals who can provide letters of recommendation to: http://cshl.peopleadmin.com/postings/9250

 

Only candidates selected for an interview will be contacted.

 

For any questions pertaining to this opportunity please email your inquiry to osp@cshl.edu.

 

For more information about CSHL and our cancer research program, please visit http://www.cshl.edu/Research/Cancer/Cancer-Center.html

 

Requisition Specific Questions

 

Required fields are indicated with an asterisk (*).

 

 

  • * Please list in chronological order any graduate or professional schools attended, your degree(s) (eg. PhD, MD, DVM), noting the location and date the degree was or is expected to be awarded. (Please refrain from referring to other documents)

     

(Open Ended Question)

 

 

 

  • * Please list any previous postdoctoral or residency training experience (if applicable). Please refrain from referring to other documents.

     

    (Open Ended Question)

     

  • * Please provide the title of your doctoral thesis and the name of your thesis advisor(s). Please refrain from referring to other documents.

     

    (Open Ended Question)

     

  • * How many months/years of postdoctoral training experience do you have?

     

    (Open Ended Question)

     

  • * Please indicate the fields that you are interested in seeking training in at CSHL (check all that apply):

     

    • Cancer genetics
    • Cancer related signal transduction
    • Cancer related gene regulation and cell proliferation
    • Cancer related Quantitative Biology
  • * If you are authorized to work for all employers in the US on a full time basis, will you now or in the future require sponsorship for an employment-authorized visa status?

     

      • Yes
      • No

     

Applicant Documents

 

 

Required Documents

  • Resume or Curriculum Vitae
  • Cover Letter

Optional Documents

 


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Senior Scientist CRISPR

Date Posted:
3/9/2017

GQR Global Products

MA

My Client a VC Backed drug discovery company employing cutting-edge functional genomics technology to identify novel pathways and targets involved in oncology and immuno-oncology. is seeking talented scientists.

 

 

 

We’re looking for exceptional PhD level immunologists. You’d be part of a team with deep expertise in immunology, functional genomics, oncology, and drug discovery.

 

 

 

We’re looking for candidates that have extensive experience culturing/manipulating lymphocytes and performing functional immunoassays, both in vitro and in vivo.

 

 

 

  • PhD with a postdoctoral fellowship in immunology or oncology with a focus on molecular immunology.

     

  • Technical expertise in gene editing immune cells desired.

     

  • 0-3 years of experience in an industrial setting with a focus on immuno-oncology a plus.

     

  • Experience managing scientists.

     

  • Proficiency in a wide range of immunological laboratory techniques.

     

  • A track record of communicating scientific concepts and strategies effectively, including a publication record in top-tier, peer reviewed journals.

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Genomics Product Specialist

Date Posted:
3/9/2017

Agilent

MD

Job description

Agilent is the premier laboratory partner for a better world. We provide life science, diagnostic and applied market laboratories worldwide with instruments, services, consumables, applications and expertise. Agilent enables customers to gain the insights they seek -- so they can do what they do best: improve the world around us. Information about Agilent is available at www.agilent.com.

 

The Diagnostic and Genomics Group (DGG) at Agilent is seeking an experienced, enthusiastic, self-motivated and people-oriented individual to join our successful and dynamic Americas Field Operations (AFO) team as a Product Specialist.

 

In a direct sales role, as a Genomics Product Specialist, you will be responsible for driving sales of Agilent Technologies' line of high performance Microarray, NGS Automation, CRISPR/Cas9 Gene Editing and Next Generation Sequencing (NGS) products and associated software solutions within this territory. As an integral member of the field sales team, you will use your excellent technical sales track record to focus on acquiring new customers while retaining and growing the existing installed base of customers. As the Product Specialist, you will be expected to develop and implement successful strategies and tactics to sell complex Genomic solutions within this competitive marketplace. In collaboration with your regional Genomics team, you will also maintain and expand relationships with strategically important large customers in the assigned territory, such as key research institutes, pharmaceutical companies, consortia and other organizations, in line with Agilent's corporate strategy.

 

Key Responsibilities

 

  • Driving sales of high performance Genomic products and services in a defined territory
  • Conduct presentations and product usage demos with and without Field Applications Scientist (FAS) assistance
  • Contribute to developing effective strategies and tactics that will enable Agilent to gain market share in the Territory
  • Focus on strategic product applications (NGS, Gene Expression, CGH, CRISPR) and solutions in strategic accounts
  • Provide constructive feedback from customers into Agilent to help guide continual development of products that more effectively address customers' needs
  • Participate and be an active member in regional discussion groups and forums
  • Understand Genomics in Basic Science, Clinical Research, Government/Non-Profit, and Biotech/Pharmaceutical market segments and recognize trends that impact buying of Agilent products
  • Develop and maintain strategic customer relationships
  • Represent Agilent to the customer AND the customer to the company

     

Agilent inspires and supports discoveries that advance the quality of life. We provide life science, diagnostic and applied market laboratories worldwide with instruments, services, consumables, applications and expertise. Agilent enables customers to gain the answers and insights they seek –– so they can do what they do best: improve the world around us. Information about Agilent is available at www.agilent.com.

 

Requirements

 

  • BS/MS in a Life Sciences discipline, or equivalent; advanced degree preferred;
  • 5+ years related direct sales experience with a demonstrated track record of successfully selling against a quota
  • High level of experience in microarrays and/or NGS
  • Technical knowledge and domain knowledge in the research and diagnostic sector of the pharmaceutical industry (profit and not for profit). Knowledge of the clinical research marketplace
  • Industry/Application expertise. Working knowledge of competitive products (specifications, value propositions, price points)
  • Comfortable interfacing with senior managers within your accounts.
  • Demonstrated commercial selling skills. Strong business development, negotiation and closing skills.
  • Effective interpersonal communication and telephone sales skills.
  • Solid self-management and organizational and prioritization skills
  • Must be able to travel up to 50% of the time.

     

Agilent Technologies, Inc. is an Equal Employment Opportunity and Affirmative Action employer. We value diversity at all levels. All individuals, regardless of personal characteristics, are encouraged to apply. All qualified applicants will receive consideration for employment without regard to sex, pregnancy, race, religion or religious creed, color, gender, gender identity, gender expression, national origin, ancestry, physical or mental disability, medical condition, genetic information, marital status, registered domestic partner status, age, sexual orientation, military or veteran status, protected veteran status, or any other basis protected by federal, state, local law, ordinance, or regulation and will not be discriminated against on these bases.

 

For more information about equal employment opportunity protections, please view the ‘EEO is the Law’ poster available here:

 

https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf,

 

https://www.dol.gov/ofccp/regs/compliance/posters/pdf/OFCCP_EEO_Supplement_Final_JRF_QA_508c.pdf

 

Agilent Technologies, Inc., is committed to diversity in the workplace and strives to support candidates with disabilities. If you have a disability and need assistance with any part of the application or interview process or have questions about workplace accessibility, please contact +1-262-754-5030 (US and Canada only) or email job_posting@agilent.com. EOE AA M/F/Vet/Disability

 

Desired Skills and Experience

 

Qualifications:

 

 

 

Requirements:

 

- BS/MS in a Life Sciences discipline, or equivalent; advanced degree preferred;

 

- 5+ years related direct sales experience with a demonstrated track record of successfully selling against a quota

 

- High level of experience in microarrays and/or NGS

 

- Technical knowledge and domain knowledge in the research and diagnostic sector of the pharmaceutical industry (profit and not for profit). Knowledge of the clinical research marketplace

 

- Industry/Application expertise. Working knowledge of competitive products (specifications, value propositions, price points)

 

- Comfortable interfacing with senior managers within your accounts.

 

- Demonstrated commercial selling skills. Strong business development, negotiation and closing skills.

 

- Effective interpersonal communication and telephone sales skills.

 

- Solid self-management and organizational and prioritization skills

 

- Must be able to travel up to 50% of the time.

 

Agilent Technologies, Inc. is an Equal Employment Opportunity and Affirmative Action employer. We value diversity at all levels. All individuals, regardless of personal characteristics, are encouraged to apply. All qualified applicants will receive consideration for employment without regard to sex, pregnancy, race, religion or religious creed, color, gender, gender identity, gender expression, national origin, ancestry, physical or mental disability, medical condition, genetic information, marital status, registered domestic partner status, age, sexual orientation, military or veteran status, protected veteran status, or any other basis protected by federal, state, local law, ordinance, or regulation and will not be discriminated against on these bases.

 

For more information about equal employment opportunity protections, please view the ‘EEO is the Law’ poster available here:

 

https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf,

 

https://www.dol.gov/ofccp/regs/compliance/posters/pdf/OFCCP_EEO_Supplement_Final_JRF_QA_508c.pdf

 

Agilent Technologies, Inc., is committed to diversity in the workplace and strives to support candidates with disabilities. If you have a disability and need assistance with any part of the application or interview process or have questions about workplace accessibility, please contact +1-262-754-5030 (US and Canada only) or email job_posting@agilent.com. EOE AA M/F/Vet/Disability


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Equity Research Associate

Date Posted:
3/9/2017

Evercore

NY

We are hiring an associate to support our pharma and biotech (Small and Large cap) coverage.

 

Responsibilities:

The candidate will work on a team with other associates to support the senior research analyst in the coverage of biotechnology and pharmaceutical companies. Key responsibilities will include building and maintaining financial models, creating in-depth analyses and research reports and rapidly analyzing how investment theses change after material events.

This position is located in New York.

 

Experience and Qualifications:

¦ Advanced science degree: an MD or PhD in the biosciences is preferred

¦ Strong financial modeling skills required (meaning can easily build an integrated I/S, B/S, CFS and DCF forward-looking model in Excel)

¦ Demonstrated achievement of excellence (really high grades / test scores; prior promotions, etc, etc)

¦ Strong analytical skills (financial and mathematical)

¦ Strong communication skills

¦ Hard working, willing to work long hours

¦ Team player with collegial attitude

 

About Evercore ISI:

Established in 1995, Evercore is a leading global independent investment banking advisory firm. Evercore advises a diverse set of investment banking clients on a wide range of transactions and issues and provides institutional investors with high quality equity research, sales and trading execution that is free of the conflicts created by proprietary activities. The Firm also offers investment management services to high net worth and institutional investors. With 27 offices and affiliate offices in North America, Europe, South America and Asia, Evercore has the scale and strength to serve clients globally through a focused and tailored approach designed to meet their unique needs. More information about Evercore can be found on the Company’s website at www.evercore.com

 

 

To Apply:
Please apply with your resume and reference "Equity Research Candidate.”

Apply through https://www.dropoutclub.org/jobs/list/


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Equity Research Fellowship

Date Posted:
3/6/2017

Goldman Sachs

NY

Job Summary & Responsibilities

GOLDMAN SACHS FIRM OVERVIEW
The Goldman Sachs Group, Inc. is a leading global investment banking, securities and investment management firm that provides a wide range of financial services to a substantial and diversified client base that includes corporations, financial institutions, governments and high-net-worth individuals. Founded in 1869, the firm is headquartered in New York and maintains offices in London, Frankfurt, Tokyo, Hong Kong and other major financial centers around the world.

DIVISIONAL OVERVIEW
Global Investment Research (GIR) provides investment recommendations by generating fundamental research and analysis of companies, industries, markets and economies. GIR analysts help our clients achieve superior returns through our creative, differentiated investment insights and ideas. Our clients include mutual funds, hedge funds and pension funds, among others.

Goldman Sachs is seeking PhD candidates or graduates with non-finance backgrounds to participate in a 6 month fellowship. The Fellowship will enable PhDs to explore a potential career transition into Equity Research. The Fellows are provided with training and hands-on experience on a research team as well as networking and mentorship opportunities.  The Fellowship:

•             Is open to PhDs in math, technology, or science related disciplines
•             Does not require finance experience however, an interest in investing or a basic knowledge of the markets is helpful.

SAMPLE RESPONSIBILITIES
•             Build and maintain financial models
•             Market share, macro trend, and cross company and sector data analyses
•             Company specific projects
•             Update monthly reports, marketing books, and weekly reports
•             Update and maintain daily valuation sheets

 

 

Preferred Qualifications

•             Excellent verbal and written communication skills
•             Meticulous attention to detail and strong organizational skills
•             Exceptional analytical skills, lateral thinking, and judgment
•             A proactive approach and a high level of enthusiasm
•             Experience with Microsoft Office applications (Excel, Word, Outlook)
•             Ability to meet aggressive deadlines


Goldman Sachs is an equal employment/affirmative action employer Female/Minority/Disability/Vet.  © The Goldman Sachs Group, Inc., 2015.  All rights reserved.


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Teaching Postdoc

Date Posted:
3/6/2017

Loyola University

MD

nclusive Excellence Postdoctoral Teaching Fellow
Faculty Type Non Tenure Track Fulltime
Office/Department School of Education
If Temporary or Visiting, Estimated End Date: 06/08/2019
Position Duties

Fellows teach two courses in Loyola’s undergraduate and graduate programs per semester—such as STEM-related methods, research methods and design, and learning sciences—and will also be provided time and resources to establish a research agenda. Fellows are partnered with both a School of Education department mentor and a University mentor to support their teaching and scholarship. It is expected that Fellows become active members of the School of Education community by fulfilling other service responsibilities, such as collecting accreditation data, and supporting student initiatives and departmental events.

Required Qualifications

(1) an earned doctorate in education or closely related field by August 2017; (2) successful teaching experience in K-12 settings; (3) knowledge of national standards and trends in education; and (4) evidence of participation in professional organizations. Applicants should also possess an awareness of and interest in the educational mission of Jesuit higher education. Eligible candidates must have received their Ph.D. no earlier than 2013. The two-year Fellowships include research funds, comprehensive mentorship, and access to a consortium of postdoctoral diversity programs at participating Jesuit institutions.

Preferred Qualifications

(1) experience with urban education, particularly within culturally and linguistically diverse contexts; and (2) experience teaching undergraduate or graduate courses.

Job Posting Date 02/01/2017
Priority Application Deadline Date 03/15/2017
Job Close Date  
Anticipated Start Date 08/24/2017
University Description

Loyola University Maryland is a Jesuit, Catholic university committed to the educational and spiritual traditions of the Society of Jesus and to the ideals of liberal education and the development of the whole person. Accordingly, Loyola inspires students to learn, lead, and serve in a diverse and changing world. Loyola’s beautiful, historic Evergreen campus is located in Baltimore, and its graduate centers are in Timonium and Columbia. Loyola enrolls 4,000 undergraduate and 2,000 graduate students across the Sellinger School of Business and Management, the School of Education, and Loyola College of Arts and Sciences. Founded in 1852, Loyola is one of 28 Jesuit colleges and universities in the United States and the first to bear the name of Saint Ignatius Loyola, founder of the Society of Jesus.

Diversity Statement

Loyola University Maryland strongly values the benefits that diversity brings to the workplace. In accord with its Ignatian values, the University is committed to creating and promoting a community that recognizes the inherent value and dignity of each person. Loyola University Maryland does not discriminate on the basis of race, sex, color, national or ethnic origin, age, religion, disability, marital status, sexual orientation, gender identity, genetic information, military status, or any other legally protected classification. The University recruits, hires, and promotes in accord with this policy and its Core Values.

Special Instructions to Applicants

Use “Option 1” for the teaching philosophy statement.

Successful candidates for any staff, faculty, or administrative position at Loyola University Maryland will be subject to a pre-employment background check.

Quicklink for Posting http://careers.loyola.edu/postings/2657

Applicant Documents


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Scientist III Cell Biology

Date Posted:
3/6/2017

Thermo FIsher

MD

Job Description
Job Title: Scientist III, Cell Biology
Location: Frederick, MD
Reports to: Sr. Staff Scientist, Cell Biology, Cell Biology

When you’re part of the team at Thermo Fisher Scientific, you’ll do important work, like helping customers in finding cures for cancer, protecting the environment or making sure our food is safe. Your work will have real-world impact, and you’ll be supported in achieving your career goals.

We are looking for a highly skilled and motivated individual to join Cell Biology for Scientist III position focused on commercialization of products in the area of hepatic and cell biology. Key areas of research for this position will include development of more advanced cell culture technologies within the hepatic space with a focus on hepatocyte and NPC isolation and culture.

Specific duties for this position will include:

  • Leading major R&D project(s), designing and executing experiments while working in cross-functional product commercialization teams.
  • Troubleshooting experiments and presenting data to project teams and management.
  • Identifying and solving complex problems associated with key experimental and project goals, and contributing ideas to improve on existing protocols, processes and approaches.
  • Maintain scientific visibility and credibility by active familiarization with literature directly associated with the assigned projects, maintaining familiarity with the state of the art approaches and publishing in peer reviewed journals.
  • Comply with all company safety regulations and procedures.
  • A successful candidate will have the ability to effectively handle multiple tasks and learn quickly.
  • Effective communication skills and the ability to work in team environment are essential.


Education

  • PhD or MS in Molecular and/or Cell Biology, or other related fields


Minimum Qualifications:

  • Strong knowledge in hepatic biology and ADME/Tox.
  • Strong animal surgical and handling work experience.
  • Experience in primary hepatocyte isolation and culture from human tissue and rodents.
  • Willingness to learn new surgical techniques and survival surgeries in small animals.
  • Experience in basic molecular biology including PCR, Western blot, and ELISA required.
  • Strong publication record desirable
  • Ability to work in dynamic, fast paced team environment
  • Effective communication/interpersonal skills
  • Able to design, execute, and analyze experiments with a low level of supervision required
  • Maintain and document laboratory protocols and notebooks
  • Perform other related duties as required and/or assigned
  • The position will require non-standard working hours (evenings and weekends) due to the unpredictable nature of tissue availability as well as for maintenance of cell culture experiments based on projects assigned


This position has not been approved for Relocation Assistance.

At Thermo Fisher Scientific, each one of our 50,000 extraordinary minds has a unique story to tell. Join us and contribute to our singular mission—enabling our customers to make the world healthier, cleaner and safer. Apply today http://jobs.thermofisher.com

Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.

*IND-LSG


Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.


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Lab Research manager Center for Vaccine Development

Date Posted:
3/6/2017

University of Maryland

MD

The University of Maryland, Baltimore (UMB), Center for Vaccine Development (CVD) is seeking a Laboratory Research Manager to manage a vaccine development project. The candidate will coordinate laboratory activities to develop a new vaccine. The candidate will work in a highly collaborative environment to achieve the project goals. The candidate will also perform laboratory experiments including genetic engineering of bacteria, animal experiments and assessment of antibodies elicited by the vaccine. The candidate will oversee and train staff, maintain and manage documents including reports and will communicate with external investigators. This position has the authority to formulate, affect, interpret, or implement management policies or operating practices.

 

Benefits Information

 

UMB offers a generous benefits package that includes 22 vacation days, 14 floating and holidays, 15 sick days; comprehensive health insurance and retirement options; and tuition remission for employees and their dependents at any of the University System of Maryland schools.

 

Essential Functions

  • Manage laboratory staff including training, scheduling, coordinating and delegating work, monitoring and evaluating performance to promote maximum staff member benefit and effectiveness as well as overall functional productivity.
  • Manage the development and execution of project research studies. Revises studies, in consultation with upper management or principal investigator, to meet changing needs and requirements and enforces standards.
  • Manage laboratory operations including the budget, ensuring quality control and safety compliance, developing policies and procedures, and ordering supplies. Identify and address issues and deficiencies and implement effective solutions.
  • Perform laboratory maintenance and laboratory research activities required by the study(s).
  • Assemble and assist with literature research, editing and preparing manuscripts, scientific illustrations and computer graphics for publication.
  • Provide for establishment or development of laboratory by evaluating equipment or machinery to be ordered, planning interactions with IT systems, and drafting Standard Operating Procedures for using new equipment.
  • Foster and support a conducive consultant/client environment, providing business unit and campus representatives with assessment, training, and advisement in research area.
  • Perform other related duties as assigned.
 
Qualifications
  

Education: Bachelor’s degree in Biology, Chemistry or field of study related to the research of the laboratory.

 

Experience: Six (6) years of experience in laboratory research including four (4) years in microbiology, immunology or molecular biology.

 

Supervisory: Two (2) years of direct supervision or responsibility for training, work coordination, and monitoring the work of others.

 

Preferred: PhD in biology, microbiology, immunology or related field is preferred.

 

Knowledge, Skills, and Abilities

  • Possess knowledge of vaccines and immunotherapeutic as well as Good Laboratory Practices (GLP) and documentation. Able to perform position in compliance with all requirements, regulations, and laws. Ability to maintain high standards with the work being performed and maintain awareness with trends and influences. Ability to understand and utilize scientific/medical terminology and research theory in both verbal and written communications. Assumes personal responsibility for all outcomes; makes effective and timely decisions; and learns how to effectively use technology. Maintains productivity and uses knowledge strategies to increase knowledge base.
  • Ability to effectively communicate both verbal and written thoughts, ideas, and facts. Interprets and understands written information and is able to listen attentively to verbal and non-verbal cues that lead to a deeper understanding. Ability to maintain confidentiality of subjects and information obtained.
  • Ability to work cooperatively with others and demonstrates professional, ethical, respectful, and courteous behavior when interacting with others. Demonstrate pleasant and positive interactions with other to meet customer expectations, and provide follow up with customers. Reaches compromise and consensus to influence and negotiate. Remains calm and is able to manage conflict, and works well with a diverse workforce. Approachable style allows others to be open in sharing thoughts and ideas. Able to make independent decisions that are a matter of significance for the unit.

 

Hiring Range: Commensurate with education and experience

 

If accommodations are needed for a disability, please contact Staffing & Career Services at 410-706-2606, Monday – Friday, 8:30am – 4:30pm EST. Maryland Relay can be accessed by dialing 711 (in-state) or 1-800-735-2258.

 

Equal Opportunity/Affirmative Action Employer. Minorities, women, protected veterans, and individuals with disabilities are encouraged to apply.

 

Job

: Exempt Staff - E3327F
Employee Class : Exempt Regular
Full Time/Part Time: Full-Time

Shift

: Day Job
Financial Disclosure: No

Organization

: Medicine

Job Posting

: Feb 22, 2017

Unposting Date

: Mar 13, 2017, 10:59:00 PM

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Sr. Technology Licensing Associate

Date Posted:
3/6/2017

JHU

MD

Sr. Technology Licensing Associate

Classified Title: Sr. Technology Transfer Associate

Requisition #: 311971

Range: PG

Level: 4

Salary: $89,557 - $123,187

Status: Full Time

School: Academic Centers

Location: JH at One Charles Center

Location City: Baltimore

Location State: MD

Resume Required for Application: Yes

Area of Interest: Other

Contact: Human Resources 443-997-5100

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General Description

 

Reporting to a Director of Licensing, this person independently manages a portfolio of life science technologies in order to source, negotiate and execute high value, intellectual property licenses.

Essential Job Functions:
  • Provides sell-side and business development activities around intellectual property commercialization.
  • Develops positive relationships with inventors with the intention of identifying attractive JHU technologies for licensing to start up or established companies.
  • In concert with peers, makes decisions around patenting, marketing and licensing of JHU inventions.
  • Engages with investors and companies to determine their needs and identifies applicable JHU technologies for licensing.
  • Negotiates high value intellectual property licenses for optimal deal structure, valuation and compliance.
Scope of Responsibility
  • Works under the direct supervision of a Director of Licensing in evaluation, marketing and agreement negotiation activities. May manage or mentor junior personnel as assigned.
Decision Making
  • Makes recommendations concerning investments in technologies.
Authority
  • May direct the activities of staff or a function. May not commit JHU to agreement terms without supervisor approval.

 

Qualifications

 

An advanced degree in the life sciences, or business required. PhD, or combination of degree in life sciences with an MBA strongly preferred.

Candidate will have licensing experience in a high performing technology transfer office that is typically gained through a minimum of 4 years of licensing and technology transfer experience; and/or a startup or biotechnology company with business development and deal execution experience.

Candidate will have a working knowledge of intellectual property prosecution, technology valuation and license structure. Most importantly, candidate will have a robust deal sheet of exclusive licenses and options of life science technologies.

Required Skills:

  • Must have the ability to understand complex technologies.
  • Must have knowledge and experience in negotiating business contracts, especially in technology licensing.
  • Knowledge and experience in life sciences or physical sciences preferred.
  • Experience in marketing and sales of intellectual property desired.
  • Must have the ability to work independently and as a member of a team.
  • Must demonstrate outstanding work ethic and desire and ability to work in fast-paced high-expectation environment.
  • Must be a self-starter capable of handling a docket of highly technical inventions, managing a complex patent portfolio, and marketing and licensing technology with minimal supervision.

 


NOTE: The successful candidate(s) for this position will be subject to a pre-employment background check.

If you are interested in applying for employment with The Johns Hopkins University and require special assistance or accommodation during any part of the pre-employment process, please contact the HR Business Services Office at 443-997-5100. For TTY users, call via Maryland Relay or dial 711.


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Proteomics Mass Spec Senior Technical Specialist

Date Posted:
3/6/2017

KAUST

INT

Proteomics/Mass Spectrometry - Senior Technical Specialist KAUST is an international university dedicated to advance science and technology through innovative and collaborative research and addressing challenges of regional and global significance. Based near Jeddah, Saudi Arabia, KAUST has attracted top-notch faculty and staff from all over the world, especially from countries such as USA, Germany, China, the UK, Australia, Japan, and Italy. Citizens from more than 100 nations are represented on the university campus and in the KAUST community. We are currently seeking a Senior Technical Specialist for Proteomics at the Bioscience Core Laboratory (BCL). The laboratory covers different areas such as genomics, proteomics, protein expression, and bioinformatics. The laboratory is state-of-the-art, and our team members have extensive experience in the technological areas. For Proteomics the lab holds Orbitrap Fusion Lumos, QExactive HF, TripleTOF 5600, Maxis Q-TOF and Ultraflex MALDI-TOF/TOF. Job Summary: The senior technical specialist in this role will be working on high-throughput proteomics. The person demonstrates expertise and independent working knowledge in a range of techniques including sample preparation for proteomics, hands-on LC-MS and proteomics data analysis. The person works closely with the team lead and other members of the core unit. The work involves method development, assay assessments and standardized experiments. We are a core lab facility and the working environment and mentality is service- and support-oriented in a cooperative spirit. The person in this position must be open to a fast-changing environment, and willing and supportive of alterations. Major Responsibilities: ? Provide consultation to scientists and students ? Run standardized and customized proteomics sample preparation independently ? Operate standardized and customized analysis on sophisticated LC-MS ? Train users on sample preparation, equipment and data analysis ? Expand methods and protocols for proteome sample and data analyses ? Obtain and deliver reliable and excellent quality of data and results at all times ? Maintain and manage the mass spectrometry equipment ? Identify gaps and provide feedback to all technical aspects of proteomics portfolio, or suggestions for improvements ? Collaborate efficiently with other groups internally and externally ? Stay-up-to-date with new technologies Competencies: ? A bachelor degree or above in cell biology, biochemistry, molecular biology or similar ? Minimum 2 years of experience in mass spectrometry based proteomics ? Experience in analyzing large-scale proteomics data or ability to write script is a plus ? Independently perform preventative maintenance and ability to troubleshoot equipment ? The desire to work in a team dedicated to achieving highest quality analytical results ? Ability to work with others, initiative, and ability to interact with a broad range of individuals within the University and Industrial partners and be reliable Located on the beautiful Red Sea coast of Saudi Arabia, KAUST sets exceptional standards in residences, recreational facilities and boasts a truly multicultural environment which can be enjoyed by all. Life on the Campus provides ample opportunities and time to keep work and life in harmony – from vacations and holidays to an inviting campus community on the shores of the Red Sea, with all the seaside amenities and recreation facilities of a fine resort. Employees are very well looked after, with packages including tax-free salary, relocation, accommodation and various additional incentives. Contact: stine.buechmannmoeller@kaust.edu.sa Core Labs website: https://corelabs.kaust.edu.sa/ KAUST website: https://www.kaust.edu.sa/en Live and work at KAUST: https://www.kaust.edu.sa/en/live-work


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Single Cell Genomics Scientist Flow Cytometry

Date Posted:
3/6/2017

KAUST

INT

Single Cell Genomics Scientist with flow cytometry experience KAUST is an international university dedicated to advance science and technology through innovative and collaborative research and addressing challenges of regional and global significance. Based near Jeddah, Saudi Arabia, KAUST has attracted top-notch faculty and staff from all over the world, especially from countries such as USA, Germany, China, the UK, Australia, Japan, and Italy. Citizens from more than 100 nations are represented on the university campus and in the KAUST community. We are currently seeking a Scientist for Single Cell Genomics at the Bioscience Core Laboratory (BCL). The laboratory covers different areas such as genomics, proteomics, protein expression, and bioinformatics. The laboratory is state-of-the-art, and our team members have extensive experience in the technological areas. For Single cell analysis the lab holds BD influx, Fluidigm C1, Biomark HD, and a Chromium (10X genomics). Job Summary: The scientist in this role will be the primary team member working on single-cell analysis. The scientist demonstrates scientific and operational expertise in a range of techniques related to cell sorting, genomics and gene expression analysis. The person in this role works closely with the team lead and other members of the core unit. The work involves method development, assay assessments and standardized experiments. We are a core lab facility and the working environment and mentality is service- and support-oriented in a cooperative spirit. The person in this position must be open to a fastchanging environment, and willing and supportive of alterations. Major Responsibilities: ? Operate multi-parameter flow cytometers, high speed cell sorter, data acquisition and analysis as used in environmental and biomedical research ? Operate other types of equipment such as single-cell platforms, sequencing and qPCR instruments. ? Provide consultation to scientists and students ? Maintain and manage the flow cytometry equipment as well as single-cell platforms ? Train users on equipment ? Exhibit the highest degree of reliability and accuracy to assure quality results ? Stay-up-to-date with newest technologies ? Collaborate efficiently with other groups internally and externally to set up new projects on a high scientific level ? Expand methods for sample analyses and the knowledge to other technologies or scientific challenges as well as new project opportunities Competencies: ? A PhD degree in cell biology, biochemistry, molecular biology or similar ? Minimum 3 years of experience in flow cytometry. ? Extensive experience in high performance and multi-color fluorescence activated cell sorting will be a plus. ? Insight into NGS libraries and microfluidics platforms ? The desire to work in a team dedicated to achieving highest quality analytical results ? Ability to work with others, initiative, and ability to interact with a broad range of individuals within the University and Industrial partners and be reliable Located on the beautiful Red Sea coast of Saudi Arabia, KAUST sets exceptional standards in residences, recreational facilities and boasts a truly multicultural environment which can be enjoyed by all. Life on the Campus provides ample opportunities and time to keep work and life in harmony – from vacations and holidays to an inviting campus community on the shores of the Red Sea, with all the seaside amenities and recreation facilities of a fine resort. Employees are very well looked after, with packages including tax-free salary, relocation, accommodation and various additional incentives. Contact: stine.buechmannmoeller@kaust.edu.sa Core Labs website: https://corelabs.kaust.edu.sa/ KAUST website: https://www.kaust.edu.sa/en Live and work at KAUST: https://www.kaust.edu.sa/en/live-work


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Research Support Specialist Proteomics

Date Posted:
3/6/2017

Rockfeller University

NY

Job opening in the Proteomics Resource Center at The Rockefeller University The Rockefeller University, a world-renowned center for research and graduate education in the biomedical sciences seeks a Research Support Specialist to join the Proteomics Resource Center (PRC) (http://proteomics.rockefeller.edu/). The PRC is currently staffed with five scientists and equipped with state-of-the-art instrumentation, including a Q-Exactive Plus and a Fusion Lumos. PRC staff work and collaborate on a wide variety of projects with Rockefeller investigators as well as with scientists from other not-for-profit institutions. Samples ranges from small molecules over parts-of-a-protein to thousands of proteins. Examples of projects include nucleoside quantitation, analysis of secreted mosquito peptides, and quantitative profiling of exosomes. The PRC has a detail-oriented style and addresses projects individually; this allows the staff to engage with many researchers and tackle a broad range of research areas. The Research Support Specialist position is ideal for a scientist with hands-on LC-MS/MS experience who has or wishes to gain additional proteomics and small molecule experience in an exciting and high-impact scientific environment. Responsibilities • maintaining and operating nano-flow and high-flow LC-MS and related equipment • interacting with and advising investigators with regard to proteomics experiments • developing and implementing technologies in the Center • processing, analyzing, and interpreting data