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Medical Scientist Oncology

Date Posted:
3/25/2017

Astra Zeneca

MD

Location:Gaithersburg, Maryland, United StatesJob reference: R-002917Posted date: Jan. 18, 2017

 

At AstraZeneca we work together across global boundaries to make an impact and find answers to challenges. We do this with the upmost integrity even in the most difficult situations because we are committed to doing the right thing. We continuously forge partnerships that help pursue world-class medicines in new ways, combining our peoples exceptional skills with those of people from all over the globe. As a Clinical Scientist, Oncology youll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients lives. GMD (Global Medicines Development) drives late-stage development of our innovative pipeline, transforming exciting science into valued new medicines and ensuring patients around the world can access them.

 

AstraZenecas vision in Oncology is to help patients by redefining the cancer-treatment paradigm, with the aim of bringing six new cancer medicines to patients between 2013 and 2020. A broad pipeline of next-generation medicines is focused principally on four disease areas - breast, ovarian, lung and hematological cancers. As well as other tumor types, these are being targeted through four key platforms - immunotherapy, the genetic drivers of cancer and resistance, DNA damage repair, and antibody drug conjugates, underpinned by personalized healthcare and biomarker technologies.

 

Main Duties and Responsibilities

 

Were currently looking for a Medical Scientist

 

Oncology to play a leading role in our Clinical Research team. Well look to you to act as an expert in your area, working independently with guidance in only the most complex situations. You will serve as a close partner to the study physicians, coordinating the activity of a research team and holding full accountability for projects, often with Global impact. You may have the opportunity to act as a coach or team leader for more junior team members.

 

This position will be focused on combination therapies and will have key relationships internally with clinical project teams, regulatory affairs, marketing and business development, and brand or therapy area team leaders, and externally with regulatory bodies and external service providers. With our outstanding Oncology pipeline and a culture that empowers scientists to make bold decisions driven by science, this is an incredible opportunity to gain plenty of exposure to submissions and progress within a core therapeutic area.

 

Your main responsibilities will involve: developing and designing studies to determine the scientific or commercial viability of a particular drug or portfolio of drugs and interpret the results of these studies, either as the head of a team, or by providing expert input; contributing to the decision making process as a valued expert to determine the commercial and scientific viability of drugs; review and interpretation of medical and clinical trial data to reach conclusions; literature searches and authoring background section of the disease from the literature search. You will have responsibility for delivery of pieces of the trials and may lead submissions from a process standpoint.

 

Essential Requirements

 

Master's degree in a scientific field supported by a proven record of managing and interpreting clinical trials.

 

Experience managing and interpreting the results of clinical trials

 

Excellent collaboration and communication skills

 

Adept at working in a global setting and matrix environment.

 

Adept at partnering with a diverse team and delivering results through taking ownership of crucial program components.

 

Desired Requirements

 

An advanced degree (i.e. PhD, PharmD) in a relevant scientific discipline.

 

Project management experience

 

Strong clinical, technical or disease area expertise in oncology is strongly preferred

 

Next Steps

 

Apply today!

 

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity. If you know someone who would be a great fit, please share this posting with them.

 

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.


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Bioinformatics Analsyt

Date Posted:
3/25/2017

Leidos

MD

Job description

Leidos Biomedical Research, Inc. (LBRI), a wholly owned subsidiary of Leidos, operates the Frederick National Laboratory for Cancer Research (FNLCR). FNLCR is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI). It is the only FFRDC dedicated to biomedical research. Through its status as an FFRDC, FNLCR provides NCI and others with a unique national resource to accelerate the development and delivery of effective preventive, diagnostic, and therapeutic products for cancer and AIDS.

 

The breadth of FNLCRs activities spans the research and development spectrum, including investigator-initiated, hypothesis-driven research into cancer and AIDS; advanced technology programs focused on genetics and genomics, proteins and proteomics, imaging, nanotechnology, bioinformatics, and laboratory animal sciences; clinical operations in support of NCI and National Institute of Allergy and Infectious Diseases (NIAID)-sponsored clinical trials, as well as NCI drug discovery and development efforts; and management and operations of biopharmaceutical development and manufacturing programs under current Good Manufacturing Practice conditions for NCI and NIAID. Administrative, procurement, financial, safety, and facilities support is provided to these R activities through state-of-the-art business processes. LBRI has approximately 1,900 employees and manages an annual operating budget of approximately $450M.

 

For more information about Leidos Biomedical Research Inc., please visit our webpage at https://www.leidos.com/about/companies/leidos-biomedical-research.

 

Program Description

 

The Advanced Biomedical Computing Center (ABCC) is a part of the Data Science and Information Technology Program at Leidos Biomedical Research, Inc. The ABCC provides technology development, scientific consultation, collaboration and training, and high-performance computing support to the NCI and NIH scientists and staff.

 

Job Description

 

This position description does not represent a current opening but may be used to identify candidates with skills and experience for positions within Leidos Biomedical Research that frequently become available. Candidates who express an interest may be considered for future positions at Leidos Biomedical Research.

 

The ABCC is seeking Bioinformatics Analyst candidates at all levels to work in the NCI Center for Cancer Research (CCR) Collaborative Research Resource (CCBR). The CCBR provides collaborative bioinformatics support to CCR investigators at the National Cancer Institute (NCI). CCBR bioinformatics analysts are responsible for

 

The analysis and interpretation of high-throughput biomedical data generated by microarray, next-generation sequencing, proteomics and metabolomics platforms

 

Designing, developing and deploying robust workflows, as well as custom scripts, to support the analysis of high-throughput data

 

Mining proprietary and publicly available biological data to generate novel hypotheses or insights

 

Presenting analysis results, in a clear and concise manner, to scientific audiences. Bioinformatics Analysts are expected to work effectively as a member of a team; coordinate activities among other groups located at the Bethesda, Frederick, Rockville and Gaithersburg NCI campuses; follow sound scientific practices and maintain effective documentation of activities and analyses. Majority of time will be spent on the main NIH campus in Bethesda.BASIC QUALIFICATIONS

 

Bachelors, Masters or PhD degree in life science/bioinformatics/math/physics/computer related field from an accredited college according to the Council for Higher Education Accreditation (CHEA)

 

Foreign degrees must be evaluated for U.S. Equivalency.

 

Below are the typical skills we are looking for in candidates:

 

Processing high throughput biomedical data: data cleaning, normalization, analysis, interpretation and visualization

 

Data analysis for complex experiments

 

Experience with high throughput analysis pipelines such as, metagenomics, ChIPSeq, RNASeq, ExomeSeq, microarray analysis

 

Experience in using tools for NGS data-processing tools

 

Familiarity with public databases: NCBI, Ensembl, TCGA, cBioPortal, Broad FireHose

 

Knowledge of database programming and working in a cluster environment

 

Ability to work in collaborative environment and contribute to team projects

 

Ability to work without close supervision

 

Below are the desired skills we are looking for in candidates:

 

Applied statistics and design of experiments

 

Application development experience

 

Experience in submitting data sets to public repositories

 

Management of large genomic data sets including integration with data available from public sources

 

Knowledge of cancer biology

 

Experience with bioinformatics tools such as: Novoalign, STAR, BWA, GATK, Samtools, Annotator, SnpEff, Limma, EdgeR, DESeq2

 

Proficiency in one, preferably two, of the following programming languages: Perl, Python, R, Java and C/C++

 

This position description does not represent a current opening but may be used to identify candidates with skills and experience for positions within Leidos Biomedical Research that frequently become available. Candidates who express an interest may be considered for future positions at Leidos Biomedical Research

 

Leidos Overview

 

Leidos is a global science and technology solutions leader working to solve the worlds toughest challenges in the defense, intelligence, homeland security, civil, and health markets. The companys 33,000 employees support vital missions for government and commercial customers. Headquartered in Reston, Virginia, Leidos reported pro forma annual revenues of approximately $10 billion for the fiscal year ended January 1, 2016 after giving effect to the recently completed combination of Leidos with Lockheed Martin's Information Systems & Global Solutions business (IS). For more information, visit www.Leidos.com. The companys diverse employees support vital missions for government and commercial customers. Qualified women, minorities, individuals with disabilities and protected veterans are encouraged to apply. Leidos is an Equal Opportunity Employer.


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Scientific Program Manager

Date Posted:
3/25/2017

Cherokee Nation Technology Solutions

MD

Our client, the Armed Forces Health Surveillance Branch (AFHSB), strives to be the central epidemiologic resource and a global health surveillance proponent for the U.S. Armed Forces. The AFHSB provides timely, relevant, actionable, and comprehensive infectious disease surveillance information to promote, maintain, and enhance the health of military and military-associated populations.

 

We are seeking a program manager with a public health/epidemiology background to provide program management support for the Global Emerging Infections Surveillance Section (GEIS) of AFHSB. The incumbent will support the client by providing GEIS program coordination and oversight services to ensure smooth operations of the GEIS program in its mission to enhance force health protection. Successful candidates will have strong program management and organizational skills and experience working with U.S. government agencies such as the DoD.

 

Responsibilities

 

  • Provide program management leadership to accomplish long-range goals and short-term objectives for the GEIS program office and the GEIS network and ensure excellence in strategic, financial, operational, tactical and organizational functions of the GEIS program;
  • Provide GEIS program coordination and oversight services to ensure smooth operations of the GEIS program, including task management, establishing timelines and milestones, and tracking deliverables;
  • Provide key support to identifying and defining process, outcome variables, and metrics, including return on investment, to assess success and failure of GEIS-funded surveillance efforts and initiatives;
  • Support the development of publications, presentations, and timely information products based on GEIS-funded surveillance for DoD leaders and other stakeholder, in support of force health protection;
  • Provide guidance on best practices for proposal management;
  • Support the review and prioritization of programmatic/focus area-specific strategies, programs, projects, and proposals to ensure alignment with overarching GEIS strategic direction, and provide recommendations on enhanced alignment and opportunities to address critical organizational gaps;
  • Provide scientific/technical input for GEIS on infectious disease surveillance projects and programs across the GEIS Focus Areas as needed;
  • Perform other duties as needed.

     

Qualifications

 

  • Graduate degree in Public Heath, Epidemiology, Biostatistics, Microbiology, Molecular Biology, or related field required; doctoral degree (PhD, MD, DO, DVM, DrPH, or related degree) preferred; minimum 8 years of experience in laboratory, research, or public health setting required;
  • Program management experience and experience in proposal management required;
  • Experience managing projects and staff to ensure timely delivery of high quality products to the government client;
  • Experience in designing or maintaining relational databases preferred;
  • Analytical and organizational skills to synthesize data into informational reports to support program evaluation;
  • Excellent organizational skills and strong oral and written communication skills;
  • Ability to collaborate with other professionals;
  • Demonstrated experience supporting Federal clients, particularly DoD, preferred;
  • Active Secret clearance preferred; applicants selected will be subject to a U.S. Government security investigation and must meet eligibility requirements for Secret clearance.

     

Applicants selected will be subject to a U.S. Government security investigation and must meet eligibility requirements for access to classified information.

 

Apply to Job # 10964 online at www.cherokee-cnts.com

 

Cherokee Nation Technology Solutions (CNTS) provides technical support services and project support personnel to its defense and civilian agency clients. CNTS specializes in locating hard to find candidates for rapid response requests throughout the country. It provides a tailored management approach for complex government programs and disciplines including information technology, science, engineering, construction, research & development, facilities management, program management, and mission support. Wholly owned by the Cherokee Nation, CNTS is part of the Cherokee Nation Businesses family of companies.

 

About

 

If you’d like more information about your EEO rights as an applicant under the law, please visit the following two sites

 

We are an equal opportunity/affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, protected Veteran status, gender identity and sexual orientation.

 

http://www.eeoc.gov/employers/upload/poster_screen_reader_optimized.pdf

 

http://www.dol.gov/ofccp/regs/compliance/posters/pdf/OFCCP_EEO_Supplement_Final_JRF_QA_508c.pdf

 

If you are an individual with a disability and require a reasonable accommodation to complete any part of the application process, or are limited in the ability or unable to access or use this online application process and need an alternative method for applying, you may e-mail CNB.Compliance@cn-bus.com for assistance. This email address is for accommodation requests only and cannot be used to inquire about the application process or status.

 

For Pay Transparency Non Discrimination provision, click here: https://www.dol.gov/ofccp/pdf/pay-transp_formattedESQA508c.pdf

Seniority Level

Mid-Senior level

Industry

  • Defense & Space
  • Research
  • Biotechnology

Employment Type

Full-time

Job Functions

  • Project Management
  • Information Technology

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Scientist Drug Product Development

Date Posted:
3/25/2017

GSK

MD

Basic Qualifications

 

  • Degree in Chemistry, Biology, Biochemistry, Pharmaceutical Sciences, or related scientific field. PhD with 0+ years of experience, or MS with 3+ years of experience, or BS with 6+ years of experience
  • A good understanding of vaccine formulation science, freeze-drying technologies and key analytical assays is required.
  • Knowledge about physical characterization of the vaccine formulation using high-end instrumentation is a plus, such as, HPLC/UPLC (Empower), Fluorescence, FRET, FTIR, DLS, DSC, etc.
  • Ability to effectively work and perform within a team of dedicated scientists is essential.
  • Must be able to solve complex problems through analytical thinking to identify and understand alternatives using knowledge gained through formal education, experience and sound judgment.
  • Must have the ability to work with cross-functional teams and communicate effectively.
  • Experience in technology transfer and scale-up of drug product processes is a plus.
  • Excellent written and oral skills are a must

     

Preferred Qualifications

 

N/A

 

Details

 

The Scientist is expected to design and execute scientific studies in support of technical programs as they progress from early development into Phase I/ II, Phase III, technology transfer and process performance qualification at the intended commercial site.

 

Responsibilities

 

  • Designs and executes specific development projects under limited direction.
  • Independently responsible for the conception, design, implementation, and interpretation of scientific and technical data to support TRD Drug Product (DP) projects.
  • Collaborates with senior scientific staff to design, implement, and interpret the data from development projects.
  • Makes sound scientific/technical and business decisions based on a balance of data, analysis and experience.
  • Functions effectively as a core team member on multiple concurrent projects and leads small projects and established work processes.
  • Solves complex problems through collaborations with others, taking a new perspective on existing solutions.
  • Provides guidance to new team members and acts as a resource for colleagues with less experience.
  • Generates strong relationships in the area of technical development with high quality partners beneficial to the organization, both internally and externally, to strengthen development/implementation of new methods/technologies.
  • Prepares and presents scientific data within Technical R&D
  • Authors and reviews technical protocols and reports in support of various project development stages.
  • Utilizes knowledge of drug development process to meet regulatory requirements appropriate for stage of development.
  • Communicates effectively within TD and with external stakeholders.

     

Contact Information

 

You may apply for this position online by selecting the Apply now button.

 

If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK HR Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).GSK is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.

 

Important notice to Employment businesses/ Agencies

 

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

 

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit GSK’s Transparency Reporting

Seniority Level

Mid-Senior level

Industry

  • Pharmaceuticals

Employment Type

Full-time

Job Functions

  • Research
  • Analyst
  • Information Technology

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Scientist I

Date Posted:
3/25/2017

Leidos

MD

Leidos Biomedical Research, Inc. (LBRI), a wholly owned subsidiary of Leidos, operates the Frederick National Laboratory for Cancer Research (FNLCR). FNLCR is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI). It is the only FFRDC dedicated to biomedical research. Through its status as an FFRDC, FNLCR provides NCI and others with a unique national resource to accelerate the development and delivery of effective preventive, diagnostic, and therapeutic products for cancer and AIDS.

The breadth of FNLCR’s activities spans the research and development spectrum, including investigator-initiated, hypothesis-driven research into cancer and AIDS; advanced technology programs focused on genetics and genomics, proteins and proteomics, imaging, nanotechnology, bioinformatics, and laboratory animal sciences; clinical operations in support of NCI and National Institute of Allergy and Infectious Diseases (NIAID)-sponsored clinical trials, as well as NCI drug discovery and development efforts; and management and operations of biopharmaceutical development and manufacturing programs under current Good Manufacturing Practice conditions for NCI and NIAID. Administrative, procurement, financial, safety, and facilities support is provided to these R&D activities through state-of-the-art business processes. LBRI has approximately 1,900 employees and manages an annual operating budget of approximately $450M.

 

For more information about Leidos Biomedical Research Inc., please visit our webpage at http://www.leidosbiomed.com/

 

Program Description

 

The Strategic Pilots Incubator (SPI) is responsible for the development and management of a portfolio of exploratory projects that are inherently multidisciplinary that impact cancer research and treatment. Projects aim to analyze the complex interactions in tumor cells and tissues and model systems, blending the best of new physics and engineering based advances with established technologies enabling new opportunities for deeper understanding of tumor biology and cancer progression. Using the latest tools in understanding human performance under stressful conditions can be used to understand and hopefully mitigate the toxic effects of cancer therapy for the patient.

 

Job Description

 

This position description does not represent a current opening but may be used to identify candidates with skills and experience for positions within Leidos Biomedical Research that frequently become available. Candidates who express an interest may be considered for future positions at Leidos Biomedical Research.

 

We are currently recruiting for an experienced biomedical engineer or scientist to support a newly established High Content Pathology Facility at the Frederick National Laboratory for Cancer Research. The new facility will revolve around tissue and single cell analysis, including circulating tumor cells, with the newly acquired Helios Imaging Mass Cytometer, as well as single cell sequencing. We are looking for a self-motivated and proactive individual interested in a cutting-edge and developing technology. The successful candidate will be taking on a pivotal role in the set up and running of the new High Content Pathology Facility. Subsequent to onsite training, candidates will be expected to be skilled in single cell imaging analysis, CyTOF mass cytometry and to develop and implement different applications of this technology.

 

The Scientist I will be responsible for: 1) Setting up and technically validating a single cell analysis laboratory at FNLCR, 2) Developing software and macros for running instrumentation, 3) the daily management and operation of the imaging system and CyTOF, 4) establishing standardized operating procedures (SOP), 5) assisting scientists in experimental design and setup, 6) setting up and maintaining an antibody bank and reagent base, and 7) data analysis.

 

Basic Qualifications

 

Qualifications:

 

  • Possession of a PhD degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) in Biomedical Science, Physical Science, Engineering, Health Care Informatics or related field or eight (8) years equivalent experience in lieu of degree.
  • Foreign degrees must be evaluated for U.S. equivalency
  • No work experience beyond the doctorate education is required for appointment at this level; however, some candidates may have had one or more years of postdoctoral research and training.
  • Strong bioengineering background with expertise in handling and analyzing large data sets including imaging data, genomic, and digital histopathology
  • Experience in microscopy and image acquisition/analysis
  • Proficiency in R and/or Python programming
  • Proficiency with Microsoft Office including Excel
  • Ability to learn new techniques and troubleshoot assays

     

Preferred Qualifications

 

  • Experience with antibody assay development
  • Prior experience with mass cytometry or flow cytometry
  • Experience with tissue and blood sample handling
  • Advantageous skills: immunocytochemistry (ICC) and immunohistochemistry (IHC) techniques
  • Familiar with usage of a Laboratory Information Management System (LIMS)

     

Leidos Overview

 

Leidos is a global science and technology solutions leader working to solve the world’s toughest challenges in the defense, intelligence, homeland security, civil, and health markets. The company’s 33,000 employees support vital missions for government and commercial customers. Headquartered in Reston, Virginia, Leidos reported pro forma annual revenues of approximately $10 billion for the fiscal year ended January 1, 2016 after giving effect to the recently completed combination of Leidos with Lockheed Martin's Information Systems & Global Solutions business (IS&GS). For more information, visit www.Leidos.com. The company’s diverse employees support vital missions for government and commercial customers. Qualified women, minorities, individuals with disabilities and protected veterans are encouraged to apply. Leidos is an Equal Opportunity Employer. Scientist / Research & Development

Seniority Level

Associate

Industry

  • Defense & Space
  • Information Technology and Services
  • Renewables & Environment

Employment Type

Full-time

Job Functions

  • Research
  • Analyst
  • Information Technology
 

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Scientist Microbiology

Date Posted:
3/25/2017

BD

MD

We are currently seeking a high-potential Senior Scientist with biological and engineering skills who can work within a multi-functional team to contribute to the development of automated solutions for the evolving clinical microbiology laboratory. Candidates for this lab-based position will have excellent skills in the design, execution, interpretation and presentation of laboratory experiments with minimal supervision and demonstrated learning agility. They will have excellent interpersonal and communication skills and enjoy working in a team environment. A basic understanding of product development and microbiology is desirable.

 

Job Description

 

We are currently seeking a high-potential Scientist with biological and engineering skills who can work within a multi-functional team to contribute to the development of automated solutions for the evolving clinical microbiology laboratory. Candidates for this lab-based position will have excellent skills in the design, execution, interpretation and presentation of laboratory experiments with minimal supervision and demonstrated learning agility. They will have excellent interpersonal and communication skills and enjoy working in a team environment. A basic understanding of product development and microbiology is desirable.

 

The successful candidate will work within the R&D microbiology team to develop, integrate and test diagnostic capabilities as part of an integrated automated platform for use in a clinical microbiology lab. In a team environment, she/he will work in the areas of specimen processing, pathogen detection, isolation, identification, and susceptibility testing of microorganisms in an automated environment, with responsibilities for the design and execution of experiments, maintaining technical data, data interpretation and generating reports. She/he will be required to communicate information and ideas clearly and effectively within a multidisciplinary group at various levels of the business.

 

Responsibilities

 

  • Works cross-functionally with a number of disciplines and departments (microbiologist, chemists, engineers, marketing, service, etc. ) to develop concepts and designs to meet the needs of a clinical microbiology lab. +
  • Works with a development group to develop and/or test breadboard designs.
  • Collaboratively performs testing on prototype instruments and execute subsequent formal validations.
  • Develops protocols and experimental procedures to address issues or evaluate potential designs.
  • Writes reports, specification or documents related to these efforts.
  • Prepares procedures, write technical reports, publish research papers, and make recommendations based on their research findings. - Innovates novel concepts, approaches, and solutions for addressing clinical microbiology needs .
  • Conceives of and documents intellectual property within the scope of the role.
  • Engages in collaborative efforts with academic, hospital and other external organizations. May have responsibility for managing third-party relationships.
  • Participates in and contribute to other programs in the business as requested.

     

Requirements

 

  • Bachelor’s degree required in the life sciences or biomedical engineering and 5 years related experience is required.
  • Candidates with an advanced degree are preferred. A PhD with postdoctoral experience is preferred.
  • Successful candidate will have a demonstrated aptitude for solving problems involving biological and instrumented or automated platforms.
  • Experience with data storage, processing and analysis is desirable.
  • The ideal candidate will have experience in a multidisciplinary development group with demonstrated communication and problem solving skills.
  • An aptitude for creative approaches to solving bio-mechanical problems is desired.

     


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Online Neuroscience Community Specialist

Date Posted:
3/25/2017

Society for Neuroscience

DC

Position Description:
The Society for Neuroscience (SfN) is searching for a Community Specialist who will be responsible for the growth of the community and discussion areas of SfN's learning and discussion website, Neuronline. This role will work with other programmatic departments to help facilitate the growth of smaller communities, along with evolving the strategy and initiatives within our digital community for the benefit of our members. The Specialist must have excellent communication skills, have knowledge of the field, and interest in social media. This would be ideal for a candidate with a science background that has an aptitude for online technology and communication.

Essential Job Functions:
Member Engagement/Online Community Management

  • Coordinate and participate in the development and implementation of strategies to increase member engagement on the Neuronline community and discussion site.
  • Develop and grow SfN programs to encourage member engagement.
  • Serve as a neuroscience subject matter expert to cultivate community for SfN members, and use that neuroscience expertise to seed conversations and connect members with like interests to one another.
  • Cultivate relationships with SfN staff "moderators" (internal SfN staff who manage society programs), helping to grow Neuronline's programmatic communities.
  • Lead monitoring of member engagement on the Neuronline community site, providing regular data, reports, and analysis on member participation and activity.
  • Lead monitoring of member discussions taking place on comment threads and in the forums.
  • Coordinate with staff from other SfN departments to integrate discussion of the SfN annual meeting, The Journal of Neuroscience, eNeuro, and other content into the forums.

Marketing/Communications

  • Lead smooth planning and implementation of Neuronline-related promotional activities and events at the SfN annual meeting in consultation with SfN's communication and marketing departments.
  • Lead the brainstorming for annual meeting and year-round marketing initiatives for Neuronline forums, working closely with communication and marketing departments.

Technology

  • Serve as first responder to any technical problems that arise within the forums, working with the platform vendor and internal technical support staff.
  • Become an expert in the community/discussion software, Discourse.
  • Learn Sitecore, the Content Management System (CMS), to enter content (written articles, video, audio) and set up pages for the Neuronline website.
  • Work in the CMS to review and troubleshoot content prior to it going live on Neuronline.

Content Development

  • Write and edit content and interview scientific experts and members as needed.
  • Draft marketing text to be distributed through SfN's e-newsletter, the SfN website,N communications vehicles

Minimum Requirements:
Education and Experience:

  • Bachelor's degree in Neuroscience or other relevant field required; Master's degree or PhD preferred
  • Experience with science communication.
  • Basic understanding of publishing online content, and ability to quickly learn new software; HTML and content management experience preferred
  • Experience facilitating on-line or in-person group discussion

Preferred Qualifications:

  • Excellent oral, written, and interpersonal communication skills.
  • Ability to multitask and set priorities, take initiative, and work within a collaborative team environment.
  • Able to plan and execute tasks, on schedule and with attention to detail.
  • Strongly proficient with Microsoft Office applications, and Internet research.
  • Functional ability in CSS considered a strong asset.
  • Experience working in Content Management Systems considered a strong asset.
  • Ability to learn and master an online community management system.
  • Strong organizational and project management skills with the ability to coordinate a diverse set of activities.

Our generous benefits package includes: medical, dental, disability and life insurance; flexible spending accounts, two retirement plans with employer matching and nonmatching contributions; 12 days of paid vacation, 12 days of paid sick leave, with additional personal leave and 10 paid holidays; gym membership reimbursement; and tuition reimbursement.

To Apply:
If this is you and you are eager to make meaningful contributions to a highly relevant and important mission, please submit a cover letter with your salary requirements and a copy of your resume for consideration online:https://sfncareers.applicantpro.com/jobs/503896.html Applications without cover letters will not be considered.

The Society for Neuroscience is wholly dedicated to recruiting, developing, and retaining a diverse group of talented people. We are committed to provide equal opportunities to all employees and applicants without regard to race, color, religion, gender, national origin, age, disability, sexual orientation, gender identity, or other protected criteria, in accordance with applicable law and we welcome Veteran applicants.

 

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Associate Director of Programs

Date Posted:
3/25/2017

Biofrontiers Institute

CO

Position Description:
At the University of Colorado BioFrontiers Institute, researchers from the life and physical sciences, computer science, and engineering work together to uncover new knowledge at the frontiers of science, and partner with industry to make their discoveries relevant. The Institute integrates faculty members from ten academic departments, facilitating their work across disciplines.
Take your career as a gifted administrator in higher education, science or engineering to the next level in this vital and challenging role working with Nobel laureate institute director, Tom Cech.

Responsibilities:

  • Leading a staff of over 20 people, periodically assessing the Institute's needs and developing strategies for positioning our staff for success.
  • Supporting BioFrontiers' leadership by advising them on strategic problem solving and planning, and implementing those plans.
  • Assessing inquiries directed to the Director and Chief Scientific Officer, determining the proper course of action and delegating to the appropriate individual.
  • Overseeing programs and strategic initiatives supporting our research community, and reporting results back to the Director and leadership team.
  • Serving as a key connection point to our partners across the university, and some key external partners.
  • Working with our Director of Operations & Finance to evaluate the effectiveness of current and proposed spending for programs and operations.

What we can offer:
Base salary for this position will be competitive and market-driven, and willdepend upon relevant background and experience. In addition, the University of Colorado offers excellent benefits, including medical, dental, retirement (with a 2-for-1 employer match), generous paid time off, tuition benefit and RTD ECO Bus Pass. The University of Colorado Boulder is one of the largest employers in Boulder County and offers an inspiring higher education environment. Learn more about the University of Colorado Boulder.

Qualifications:

What we require:

  • Bachelor's degree from an accredited institution, preferably in a scientific or engineering discipline.
  • 5 years of experience in a leadership role enabling a large team.

What you will need:

  • Outstanding managerial and interpersonal skills.
  • Proven track record of effective interaction with senior management/leadership.
  • Ability to toggle easily between big picture vision and details of implementation.
  • Ability to tackle large non-linear problems and track progress.
  • Ability to understand a range of perspectives and motivations.
  • Ability to build and maintain trust with multiple and diverse stakeholders.
  • Ability to, extract, distill, contextualize and communicate key information quickly, both verbally and in writing.
  • The capacity to enjoy a high level of responsibility and the opportunity to enable others.

What we'd like you to have:

  • Scientific or engineering background.
  • Advanced degree in science or engineering (PhD preferred).
  • At least one year -- preferably 5 years or more -- working in a higher education setting.
  • 2 years of experience in bioscience or biotech.
  • 5 years of experience in strategic planning and implementation.

Preferred qualifications may be used to further reduce the pool of applicants to those who are most highly qualified.

To Apply:
Please apply by March 28, 2017
If you have technical difficulties submitting application information, please contact the CU Careers help desk atcucareershelp@cu.edu. All other job related inquiries should be directed to the posting contact for this posting.

Application Materials Required: Cover Letter, Resume/CV Application Materials Instructions: To apply, please submit the following materials AS ONE DOCUMENT/PDF to this posting at www.cu.edu/cu-careers:

  1. A current resume.
  2. A cover letter that specifically addresses how your background and experience align with the requirements, qualifications and responsibilities of the position.

Please name your document as follows: First-Last-Resume-CL-08890.
During upload, please indicate the type of document to ensure accurate submission.


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Data Scientist

Date Posted:
3/22/2017

Booz Allen Hamilton

VA

    • USA, VA, McLean (8283 Greensboro Dr, Booz)
  • Booz Allen Hamilton has been at the forefront of strategy and technology for more than 100 years Today, the firm provides management and technology consulting and engineering services to leading Fortune 500 corporations, governments, and not-for-profits across the globe. Booz Allen partners with public and private sector clients to solve their most difficult challenges through a combination of consulting, analytics, mission operations, technology, systems delivery, cybersecurity, engineering and innovation expertise.

     

    Data Scientist

    So you want to be a Data Scientist?

     

    -Are you innately curious, a natural born problem solver, a contrarian or a risk taker?

    -Do you want to solve complex, challenging problems?

    -Do you want to have fun while doing so?

    -Do you want to work alongside others who are passionate about using data science to change the world?

     

    Booz Allen Hamilton is no longer just a consulting firm. We offer an environment in which you can create and deploy data-driven tools while serving as a trusted advisor to your clients. We solve cutting-edge commercial and government problems through research, development, and collaboration among teams working with leading edge technology. Our Strategic Innovation Group offers the best of both worlds: a start-up environment with the backing of an established consulting firm. You will be met with a 100-year history of success and a firm-wide belief that our team should lead the way in innovation by being disrupters and thought leaders in data science.

     

    Our Data Science team: In this role, you will join a diverse, collaborative, and ever-growing data science team. You will work alongside highly-skilled practitioners, including a master-class Kaggle competitor, a member of the Apache Software Foundation, and nationally recognized data science thought leaders with coverage in WSJ, HBR, and many others. You will deliver intellectual capital and solutions that enable our clients to derive the maximum value from their data while solving our clients most pressing business needs.

     

    A day in the life what our Data Scientists do:

    -Tap into the firms consulting roots to define business problems while manipulating data, developing analytical solutions, and executing models

    -Identify new opportunities to further apply advanced analytics solutions with our existing clients

    -Work across all of our markets with private and public sector clients in Energy, Financial Services, Life Sciences (Health), and Defense

    -Pioneer and champion data science for social good while working with national museums, international organizations and non-profits

    -Enhance the diversity of the firm by helping to attract, develop, and retain our existing talent

     

    This position is located in Washington, DC, Boston, MA, San Diego, CA, Houston, TX, or New York, NY.

     

    Basic Qualifications:

    -2 years of experience with advanced data analytic techniques, including data mining, machine learning, statistical analysis, and Natural Language Processing

    -1 year of experience with programming in an object-oriented programming language, including Java or Python

    -Experience in working with massive data sets, including structured and unstructured with at least 1 prior engagement involving data gathering, data cleaning, data mining, and data visualization

    -Ability to show a proven track record of weaving data and analysis into a compelling format that is client- and solutions-driven and easily digestible resulting in client approval

    -Ability to obtain a security clearance

    -BA or BS degree

     

    Additional Qualifications:

    -Experience with scientific research processes and bioinformatics, health and analytical tools related to genomics, medical imaging, phenotypic, or related data

    -Knowledge of government-funded research processes and initiatives

    -Experience with an object-oriented programming language, including Java or Python

    -Experience with articulating the overall story derived from data and analysis and explaining complex analyses and themes to non-technical and technical audiences

    -Knowledge of advanced data analytic techniques, including data mining, machine learning, statistical analysis, and Natural Language Processing

    -Ability to show a track record of solving large, complex problems

    -BA or BS degree in Statistics, Mathematics, Operations Research, EE, CS, or related fields preferred; MA or MS degree in Statistics, Mathematics, Operations Research, Biology, Bioinformatics, Biomedical Engineering, Genetics, Neuroscience, or similar health-related fields a plus; PhD degree in Biomedical Engineering, Bioinformatics, Biology, Genetics, Neuroscience, or related fields a plus

     

    Clearance:

    Applicants selected will be subject to a security investigation and may need to meet eligibility requirements for access to classified information.

     

    Integrating a full range of consulting capabilities, Booz Allen is the one firm that helps clients solve their toughest problems. by their side to help them achieve their missions.  Booz Allen is committed to delivering results that endure.

     

    We are proud of our diverse environment, EOE, M/F/Disability/Vet.


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Biological Scientist microbiology, molecular biology

Date Posted:
3/22/2017

a-tek

MD

Job description
Job Description
Clearance Level Needed: Requires U.S. Citizenship or Green Card Holder. Individual selected will be subject to a background investigation and must meet eligibility requirements for access to sensitive information.
Position Description
This position will be responsible for performing non-research molecular testing to rapidly identify and characterize potential pathogenic bacterial and viral threat agents.
Ensures incoming biological samples are processed and triaged maintaining chain of custody. Performs and interprets a variety of specialized tests and strains, detection, and identification of pathogenic microorganisms.
Prepares written and oral reports, answer questions, troubleshoot and make recommendations to the supervisor for inclusion in comprehensive reports on test findings.
Maintains and operates equipment including performing calibrations, adjustments, and to operate equipment and instruments properly and in a safe manner.
Participates in cross training related to bioterrorism and other public health emergencies.
Additionally, will be responsible for maintaining knowledge and skills related to position and program and to carry out all procedures in accordance to proper handling and storage of various biological materials.
Individual must be available 24/7/365 to respond in case of emergency.
Rotating weekends and some holidays are required.
Qualifications
Ph.D. or Master’s degree from an accredited university in microbiology, molecular biology or related course work in biological sciences, and REQUIRES at least one year of post-graduate laboratory bench experience, utilizing real time polymerase chain reaction (PCR) technology, ELISA, aseptic techniques and biological assays, and at least one year of experience serving as a Senior Scientist or Team Leader of a laboratory team/project. Bachelor’s degree from an accredited university requires four years of laboratory bench experience, including at least one year of experience as a Team Leader/Senior Scientist (total four years’ experience). BSL-3 experience is desirable.
RESUME SUBMISSION REQUIREMENTS: 1. Submission MUST include your Salary requirement (either as specific amount or acceptable range).
A-TEK, Inc. is not a recruiting agency and will not disclose any of your personal information to any outside party.


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Regulatory Health project manager

Date Posted:
3/22/2017

FDA

MD

Job description
Summary
Job Overview
Become a part of the Department that touches the lives of every American! At the Department of Health and Human Services (HHS) you can give back to your community, state, and country by making a difference in the lives of Americans everywhere. It is the principal agency for protecting the health of citizens. Join HHS and help to make our world healthier, safer, and better for all Americans.
The Center for Tobacco Products (CTP) of the Food and Drug Administration (FDA) is responsible for implementing the Family Smoking Prevention and Tobacco Control Act. This law gives FDA authority over tobacco products by adding a new chapter to the Food, Drug and Cosmetic Act. The Tobacco Control Act gives FDA the authority to regulate tobacco products and manufacturers based on the best available science and CTP is responsible for both assessing and fostering that science-base. CTP's actions have significant public health and consumer protection impact, and are among the most important issues faced by the Agency in its long and distinguished history.
This DHHS Position meets the criteria in OMB M-17-17 and is exempt from the hiring freeze.
This position is located in the Department of Health and Human Services (DHHS), Food and Drug Administration (FDA), Center for Tobacco Products (CTP), Office of Science (OS), Silver Spring, Maryland.
This vacancy is also being announced concurrently with vacancy announcement FDA-CTP-17-MP-1930389SW under merit promotion procedures. Please review that announcement to see if you are eligible for consideration under merit promotion procedures.
NOTE: Applicants must apply separately for each announcement in order to be considered.
Who May Apply: Open to all United States Citizens.
Additional selections may be made within the same geographical area FDA-wide.
Duties
Perform library and document search of technical and scientific publications regarding regulated tobacco products and projects.
Monitor the status of all projects, and serves as the primary point of contact.
Work with the team leader and branch chief to resolve both internal and application and project related problems.
Coordinate and monitor the scientific and technical review of routine submissions and projects.
Prepare letters to applications regarding administrative and regulatory issues based on input from review staff.
Prepare minutes of internal applicant meetings.
Travel Required
Occasional Travel
Travel estimated at 2%-Domestic/International
Relocation Authorized
No
Job Requirements
Key Requirements
U.S. Citizenship is required.
Only experience gained by closing date announcement will be considered.
One year probationary period may be required.
Qualifications
Basic Requirements for GS-601 Regulatory Health Project Manager:
Have successfully completed a full four-year course of study at an accredited college or university leading to a bachelor's or higher degree with a major study in an academic field related to health sciences or allied sciences appropriate to the work of the position.
In addition to meeting the basic requirement for the Regulatory Project Health Manager, GS 601-07/09, you must meet the following.
Gs-07
Have one year of specialized experience, equivalent to the GS-05 level in the Federal service, in applying basic scientific principles to carry out assignments and projects; working with and organizing a team to accomplish a variety of activities; and providing technical assistance to resolve program problems, questions, and unusual situations.
OR
Have a one year of graduate level education from an accredited college and/or university.
OR
Have a bachelor's degree as described in the Basic Qualification Requirements above and meet Superior Academic Achievement (S.A.A.) criteria. S.A.A. is based on (1) class standing, (2) grade-point average, or (3) honor society membership. Class standing -- Applicants must be in the upper third of the graduating class in the college, university, or major subdivision, such as the College of Liberal Arts or the School of Business Administration, based on completed courses. Grade-point average (G.P.A.) -- Applicants must have a grade-point average of: 3.0 or higher out of a possible 4.0 ("B" or better) as recorded on their official transcript, or as computed based on 4 years of education, or as computed based on courses completed during the final 2 years of the curriculum; or 3.5 or higher out of a possible 4.0 ("B+" or better) based on the average of the required courses completed in the major field or the required courses in the major field completed during the final 2 years of the curriculum. Grade-point averages are to be rounded to one decimal place. For example, 2.95 will round to 3.0 and 2.94 will round to 2.9. Election to membership in a national scholastic honor society -- Applicants can be considered eligible based on membership in one of the national scholastic honor societies. These honor societies are listed by the Association of College Honor Societies.
OR
Have a combination of the required experience and education for this grade level.
Gs-09
Have one year of specialized experience, equivalent to the GS-07 in the Federal service, in applying basic scientific principles to carry out assignments; leading and organizing a team to accomplish a variety of activities; and providing technical guidance to resolve program problems, questions, and unusual situations.
OR
Have two full years of progressively higher level graduate education leading to a master's degree or equivalent graduate degree in a field that is directly related to Health Sciences or Allied Sciences appropriate to the work of this position.
OR
Have a combination of the required experience and education for this grade level.
You must submit an official transcript, unofficial transcript, or a list including courses, grades earned, completion dates, and quarter and semester hours earned. If you are using education completed in foreign colleges or universities to meet the qualification requirements, you must show that the education credentials have been evaluated by a private organization that specializes in interpretation of foreign education programs and such education has been deemed equivalent to that gained in an accredited U.S. education program. For further information, click on foreign education.
Conditions Of Employment
Security and Background Requirements: Appointment will be subject to the applicant's successful completion of a background security investigation. Failure to successfully meet these requirements may be grounds for appropriate personnel action. If hired, a background security reinvestigation or supplemental investigation may be required at a later time. Applicants are also advised that all information concerning qualifications is subject to investigation. False representation may be grounds for non-consideration, non-selection or appropriate disciplinary action.
E-Verify: If you are selected for this position, the documentation that you present for purposes of completing the Department of Homeland Security (DHS) Form I-9 will be verified through the DHS "E-Verify" System. Federal law requires DHS to use the E-Verify System to verify employment eligibility of all new hires, and as a condition of continued employment obligates the new hire to take affirmative steps to resolve any discrepancies identified by the system. The U.S. Department of Health and Human Services is an E-Verify Participant.
Direct Deposit: All Federal employees are required to have Federal salary payments made by direct deposit to a financial institution of their choosing.
Pre-employment physical required: No
Drug testing required: No
License required: No
Mobility agreement required: No
Immunization required: No
Incentives may be authorized; however, this is contingent upon funds availability. If authorized, certain incentives will require you to sign a service agreement to remain in the Federal government for a period of up to 3 years. Note: This statement does not imply nor guarantee an incentive will be offered and paid. Incentives include the following: student loan repayment, superior qualifications appointment, creditable service for annual leave for prior non-federal work experience or prior uniformed military service, etc.
Bargaining Unit Position: Yes
All qualification requirements must be met by the closing of the announcement.
Please be advised that this position will be subject to FDA's prohibited financial interest regulation and may require the incumbent of this position to divest of certain financial interests. Applicants are advised to seek additional information on this requirement from the hiring official before accepting this position.
Security Clearance
Q - Sensitive
Additional Information
What To Expect Next
Once the online questionnaire is received you will receive an acknowledgement email that your submission was successful. The most highly qualified candidates will be referred to the hiring manager for further consideration and possible interview. We expect to make a selection within 45 days of the closing date of this announcement. Once this process is completed, you will be notified of your status via e-mail.
Benefits
The Federal Government offers a comprehensive benefits package!
Explore the major benefits offered to most Federal employees at https://www.usajobs.gov/Help/working-in-government/benefits/.
Other Information
If you are serving, or have served in the last 5 years (from the close of this announcement) as an Executive Branch political, Schedule C, or Non-career SES appointee, HHS/FDA may be required to obtain approval by the Office of Personnel Management (OPM) prior to beginning employment.
You can find out if you have held one of these appointment types by looking at your Standard Form 50s in your Electronic Official Personnel Folder (eOPF), in Section 5 where the legal authorities are listed. If you have served or are currently serving, you must provide a copy of your SF-50, Notification of Personnel Action, documenting this appointment. In addition, you will be required to respond to the question in the assessment and certify your responses to the questionnaire.
If you are a veteran with preference eligibility and you are claiming 5-points veterans' preference, you must submit a copy of your DD-214 (Member Copy #4) or other proof of eligibility. If you are claiming 10-point veterans' preference, you must also submit an SF-15, "Application for 10-Point Veterans' Preference" plus the proof required by that form. For more information on veterans' preference see http://www.usajobs.gov/Veterans.
Males born after December 31, 1959 must be registered or exempt from Selective Service (see http://www.sss.gov).
For information on "People with Disabilities" please visit http://opm.gov/disability/PeopleWithDisabilities.asp
Career Transition Program: This program applies to Federal workers whose positions have been deemed "surplus" or no longer needed, or an employee who has been involuntarily separated from a Federal service position within the competitive service. To receive selection priority for this position, you must be rated "well-qualified". Well-qualified means eligible applicants whose knowledge, skills, and abilities clearly exceed the minimum qualification requirements of the position. For information on how to apply and what documents to submit as an ICTAP eligible, see: http://www.opm.gov/rif/employee_guides/career_transition.asp
This job originated on www.usajobs.gov. For the full announcement and to apply, visit www.usajobs.gov/GetJob/ViewDetails/466134400. Only resumes submitted according to the instructions on the job announcement listed at www.usajobs.gov will be considered.
Seniority Level
Not Applicable

Industry
Government Administration Program Development
Employment Type
Full-time

Job Functions
Project Management Information Technology


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Microbiologist FDA

Date Posted:
3/22/2017

FDA

MD

Job description
Summary
Job Overview
Become a part of the Department that touches the lives of every American! At the Department of Health and Human Services (HHS) you can give back to your community, state, and country by making a difference in the lives of Americans everywhere. It is the principal agency for protecting the health of citizens. Join HHS and help to make our world healthier, safer, and better for all Americans.
"This HHS Position meets the criteria outlined in OMB M-17-18 and is exempt from the hiring freeze".
Positions Are Located In The Department Of Health And Human Services (DHHS), Food And Drug Administration (FDA) In Montgomery County, MD, And May Be Filled In The Following Centers
Center for Biologics & Evaluation Research (CBER) - Regulates biological products for human use under applicable federal laws, including the Public Health Service Act and the Federal Food, Drug and Cosmetic Act.
Center for Drug Evaluation & Research (CDER) Provide regulatory oversight for investigational studies during drug development and making decisions regarding marketing approval for new drugs.
Center for Devices and Radiological Health (CDRH) - Facilitate medical device innovation by advancing regulatory science, providing industry with predictable, consistent, transparent, and efficient regulatory pathways in devices marketed in the U.S.
Center for Food Safety and Applied Nutrition (CFSAN) - Responsible for the safety of the nation's domestically produced and imported foods, cosmetics, drugs, biologics, medical devices, and radiological products.
Center for Tobacco Products (CTP) - Responsible for implementing the Family Smoking Prevention and Tobacco Control Act to regulate tobacco products and manufactures based on the best available science and for both assessing and fostering that science base.
Office of Regulatory Affairs (ORA)?Inspects regulated products and manufacturers, conducts sample analyses of regulated products and reviews imported products offered for entry into the United States.
National Center for Toxicological Research (NCTR) - is a multi-disciplinary research Center. NCTR conducts scientific research to generate data for FDA decision making, and develops and supports innovative tools and approaches that FDA uses to protect and promote individual and public health.
Center for Veterinary Medicine (CVM) - Conducts research that helps FDA ensure the safety of animal drugs, food for animals, and food products made from animals; and monitors the safety and effectiveness of animal drugs on the market.
NOTE: If you wish to be considered for the Microbiologist position under Merit Promotion procedures, please apply to FDA-CR-17-MP-1926509KC. Please review that announcement to see if you are eligible for consideration under merit promotion procedures.
Who May Apply: Open to all United States Citizens.
Additional selections may be made within the same geographical area FDA-wide.
Duties
Duties Include
As a Microbiologist, GS-0403-11, you will serve as a support scientist performing scientific analysis and research to support work to identify and isolate the microbiological agents, pathogenic bacteria and contaminants from food, drugs, animal drugs, animal feed and/or study the microbiological and immunological basis of the pathogens it the transmission and control of infectious disease that threaten public health.
Plans, develops, and modifies analytical methods to study the distribution of microorganism in natural and manmade environments.
Determines the approach, methods, and procedures to use in order to obtain the information requested, taking into consideration the requirements established by Agency regulations and the Federal law.
Assists in writing comprehensive statistical and analytical reports from major scientific investigations, studies and projects.
Travel Required
Not Required
Relocation Authorized
No
Job Requirements
Key Requirements
U.S. Citizenship is required.
Only experience gained by closing date announcement will be considered.
One year probationary period may be required.
Qualifications
BASIC QUALIFICATION
Basic Requirement for Microbiology Series, 0403 Degree: microbiology; or biology, chemistry, or basic medical science that included at least 20 semester hours in microbiology and other subjects related to the study of microorganisms, and 20 semester hours in the physical and mathematical sciences combining course work in organic chemistry or biochemistry, physics, and college algebra, or their equivalent. OR Combination of education and experience: courses equivalent to a major in microbiology, biology, chemistry, or basic medical science that included courses as shown in A above, plus appropriate experience or additional education.
Additional Requirements
To qualify at the GS-11 level: In addition to meeting the basic requirement, you must have one year of qualifying experience at the GS-9 in the Federal Government obtained in either the private or public sector, performing the following tasks: Performing microbiological analysis and testing; interpreting the findings related to scientific studies; and writing analytical reports from scientific investigations, studies, or projects.
If you are claiming education as any part of your qualifications for this position, you must submit an official transcript, unofficial transcript, or a list including courses, grades earned, completion dates, and quarter and semester hours earned. If you are using education completed in foreign colleges or universities to meet the qualification requirements, you must show that the education credentials have been evaluated by a private organization that specializes in interpretation of foreign education programs and such education has been deemed equivalent to that gained in an accredited U.S. education program. For further information, click on foreign education.
Conditions Of Employment
Security and Background Requirements: Appointment will be subject to the applicant's successful completion of a background security investigation. Failure to successfully meet these requirements may be grounds for appropriate personnel action. If hired, a background security reinvestigation or supplemental investigation may be required at a later time. Applicants are also advised that all information concerning qualifications is subject to investigation. False representation may be grounds for non-consideration, non-selection or appropriate disciplinary action.
E-Verify: If you are selected for this position, the documentation that you present for purposes of completing the Department of Homeland Security (DHS) Form I-9 will be verified through the DHS "E-Verify" System. Federal law requires DHS to use the E-Verify System to verify employment eligibility of all new hires, and as a condition of continued employment obligates the new hire to take affirmative steps to resolve any discrepancies identified by the system. The U.S. Department of Health and Human Services is an E-Verify Participant.
Direct Deposit: All Federal employees are required to have Federal salary payments made by direct deposit to a financial institution of their choosing.
Pre-employment physical required: No
Drug testing required: No
License required: No
Mobility agreement required: No
Immunization required: No
Incentives may be authorized; however, this is contingent upon funds availability. If authorized, certain incentives will require you to sign a service agreement to remain in the Federal government for a period of up to 3 years. Note: This statement does not imply nor guarantee an incentive will be offered and paid. Incentives include the following: moving expenses, recruitment or relocation incentive; student loan repayment, superior qualifications appointment, creditable service for annual leave for prior non-federal work experience or prior uniformed military service, etc.
Bargaining Unit Position: Yes
All qualification requirements must be met by the closing of the announcement.
Financial disclosure statement required: No


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Biologist FDA

Date Posted:
3/22/2017

FDA

MD

Job description
Summary
Job Overview
Become a part of the Department that touches the lives of every American! At the Department of Health and Human Services (HHS) you can give back to your community, state, and country by making a difference in the lives of Americans everywhere. It is the principal agency for protecting the health of citizens. Join HHS and help to make our world healthier, safer, and better for all Americans.
This DHHS Position meets the criteria in OMB M-17-17 and is exempt from the hiring freeze. **
This Position Is Located In The Department Of Health And Human Services (DHHS), Food And Drug Administration (FDA), In Montgomery County, Maryland, And May Be Filled In The Following Centers
Center for Biologics & Evaluation Research (CBER)
Center for Drug Evaluation & Research (CDER)
Center for Devices and Radiological Health (CDRH)
Center for Food Safety and Applied Nutrition (CFSAN)
Center for Tobacco Products (CTP)
Office of Regulatory Affairs (ORA)
National Center for Toxicological Research (NCTR)
Center for Veterinary Medicine (CVM)
This vacancy is also being announced concurrently with vacancy announcement FDA-CR-17-MP-1925111SW under merit promotion procedures. Please review that announcement to see if you are eligible for consideration under merit promotion procedures.
NOTE: Applicants must apply separately for each announcement in order to be considered.
Who May Apply: Open to all United States Citizens.
Additional selections may be made within the same geographical area FDA-wide.
Duties
Plans and conducts studies and investigations concerning biological, chemical, and physical processes that affect biology resources. Modifies and adapts standard techniques, processes, and procedures; assesses, selects, and applies precedents.
Analyzes data, performs scientific tests, and conducts studies on the impact of existing or proposed management or public practices on biology resources. Develops plans for biology projects including estimate of personnel, equipment, materials, and schedules required to carry out plans.
Conducts project analyses and reviews results of studies of investigations. Evaluates the impact of the lasts technological advances in biology on novel studies conducted and on current and future programs. Manages the day-to-day operation of the laboratory, including coordinating research projects and personnel, and ensuring availability of equipment and supplies.
Travel Required
Not Required
Relocation Authorized
No
Job Requirements
Key Requirements
U.S. Citizenship is required.
Only experience gained by closing date announcement will be considered.
One year probationary period may be required.
Official Transcript required.
Qualifications
Basic Qualification Requirements for Biologist, GS-401:
Degree: biological sciences, agriculture, natural resource management, chemistry, or related disciplines appropriate to the position.
OR
Combination of education and experience: Courses equivalent to a major, as shown in A above, plus appropriate experience or additional education.
AND
Specialized experience requirement: In addition to meeting the Basic Qualification Requirement outlined above, you must meet the minimum qualifications below for the Biologist, GS-401-13.
I have at least one year of specialized experience equivalent to the GS-12 grade level in the Federal service, which includes planning and conducting studies and investigations pertaining to biological sciences; performing scientific tests and analyzing results for valid data; evaluating inaccurate data and recommending solutions; and assist with managing the operation of a laboratory.
If you are claiming education as any part of your qualifications for this position, you must submit an official transcript, unofficial transcript, or a list including courses, grades earned, completion dates, and quarter and semester hours earned. If you are using education completed in foreign colleges or universities to meet the qualification requirements, you must show that the education credentials have been evaluated by a private organization that specializes in interpretation of foreign education programs and such education has been deemed equivalent to that gained in an accredited U.S. education program. For further information, click on foreign education.
Conditions Of Employment
Security and Background Requirements: Appointment will be subject to the applicant's successful completion of a background security investigation. Failure to successfully meet these requirements may be grounds for appropriate personnel action. If hired, a background security reinvestigation or supplemental investigation may be required at a later time. Applicants are also advised that all information concerning qualifications is subject to investigation. False representation may be grounds for non-consideration, non-selection or appropriate disciplinary action.
E-Verify: If you are selected for this position, the documentation that you present for purposes of completing the Department of Homeland Security (DHS) Form I-9 will be verified through the DHS "E-Verify" System. Federal law requires DHS to use the E-Verify System to verify employment eligibility of all new hires, and as a condition of continued employment obligates the new hire to take affirmative steps to resolve any discrepancies identified by the system. The U.S. Department of Health and Human Services is an E-Verify Participant.
Direct Deposit: All Federal employees are required to have Federal salary payments made by direct deposit to a financial institution of their choosing.
Pre-employment physical required: No
Drug testing required: No
License required: No
Mobility agreement required: No
Immunization required: No
Incentives may be authorized; however, this is contingent upon funds availability. If authorized, certain incentives will require you to sign a service agreement to remain in the Federal government for a period of up to 3 years. Note: This statement does not imply nor guarantee an incentive will be offered and paid. Incentives include the following: moving expenses, recruitment or relocation incentive; student loan repayment, superior qualifications appointment, creditable service for annual leave for prior non-federal work experience or prior uniformed military service, etc.
Bargaining Unit Position: Yes
All qualification requirements must be met by the closing of the announcement.
Financial disclosure statement required: No
Security Clearance
Public Trust - Background Investigation
Additional Information
What To Expect Next
Once the online questionnaire is received you will receive an acknowledgement email that your submission was successful. The most highly qualified candidates will be referred to the hiring manager for further consideration and possible interview. We expect to make a selection within 45 days of the closing date of this announcement. Once this process is completed, you will be notified of your status via e-mail.
Benefits
The Federal Government offers a comprehensive benefits package!
Explore the major benefits offered to most Federal employees at https://www.usajobs.gov/Help/working-in-government/benefits/.
Other Information
If you are serving, or have served in the last 5 years (from the close of this announcement) as an Executive Branch political, Schedule C, or Non-career SES appointee, HHS/FDA may be required to obtain approval by the Office of Personnel Management (OPM) prior to beginning employment.
You can find out if you have held one of these appointment types by looking at your Standard Form 50s in your Electronic Official Personnel Folder (eOPF), in Section 5 where the legal authorities are listed. If you have served or are currently serving, you must provide a copy of your SF-50, Notification of Personnel Action, documenting this appointment. In addition, you will be required to respond to the question in the assessment and certify your responses to the questionnaire.
If you are a veteran with preference eligibility and you are claiming 5-points veterans' preference, you must submit a copy of your DD-214 (Member Copy #4) or other proof of eligibility. If you are claiming 10-point veterans' preference, you must also submit an SF-15, "Application for 10-Point Veterans' Preference" plus the proof required by that form. For more information on veterans' preference see http://www.usajobs.gov/Veterans.
Males born after December 31, 1959 must be registered or exempt from Selective Service (see http://www.sss.gov).
For information on "People with Disabilities" please visit http://opm.gov/disability/PeopleWithDisabilities.asp
Career Transition Program: This program applies to Federal workers whose positions have been deemed "surplus" or no longer needed, or an employee who has been involuntarily separated from a Federal service position within the competitive service. To receive selection priority for this position, you must be rated "well-qualified". Well-qualified means eligible applicants whose knowledge, skills, and abilities clearly exceed the minimum qualification requirements of the position. For information on how to apply and what documents to submit as an ICTAP eligible, see: http://www.opm.gov/rif/employee_guides/career_transition.asp
This job originated on www.usajobs.gov. For the full announcement and to apply, visit www.usajobs.gov/GetJob/ViewDetails/465651500. Only resumes submitted according to the instructions on the job announcement listed at www.usajobs.gov will be considered.


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Supervisory Veterinary Officer

Date Posted:
3/22/2017

NIH

MD

SUPERVISORY VETERINARY MEDICAL OFFICER (OPENS 4/10, CLOSES 4/14)
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES , BETHESDA, MARYLAND
Position Description:
The NIAID Vaccine Research Center (VRC) is recruiting for a supervisory veterinary medical officer to oversee preclinical research activities, investigate novel vaccine delivery methods, and serve as the head of the Translational Research Program. NIAID is a major research component of NIH and the Department of Health and Human Services (HHS).

Due to the dual research support and animal medicine functions of the position, the VRC is seeking candidates with extensive experience in virology, immunology, or a related scientific field and a doctorate in veterinary medicine. The position involves a broad spectrum of scientific research; veterinary and business management skills encompassing laboratory animal medicine research; animal program management; developing, managing, and executing in vivo animal research contracts for the VRC; financial oversight; and contract administration. The candidate will plan, manage, and analyze data from animal studies evaluating immunogenicity of vaccine candidates. Board certification in laboratory animal medicine is required, and experience in financial oversight of a large program is preferred.

The ideal candidate will be experienced in vaccine development research, nonhuman primate studies, and good laboratory practices (GLP) animal studies and will have a record of independent research and peer-reviewed publication.

Salary will be based on qualifications and experience, in the range of $128,082 - $160,300.

To Apply:
Visit www.USAJobs.gov and access vacancy announcement number NIH-NIAID-DH-17-1821107 beginning April 10, 2016. Applications must be submitted online by 11:59 p.m. on April 14, 2016.

Visit NIAID Careers for more information about NIAID and how you can join this exciting and dynamic research organization.

HHS, NIH, and NIAID are equal opportunity employers. The NIH is dedicated to building a diverse community in its training and employment programs.


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Scientist I, RAS 3D cell culture

Date Posted:
3/22/2017

Leidos

MD

Program Description:
The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish National Cancer Institute (NCI) research objectives. The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community. A major focus of the CRTP is the NCI RAS Initiative with the goal to discover new therapeutic interventions against RAS-driven cancers.

Position Description:
The Scientist I will work in support of the Frederick National Laboratory/NCI RAS Initiative in Frederick, Maryland. One of the major objectives of the RAS initiative at the Frederick National Lab for Cancer Research (FNLCR) is to dissect the biology and mechanisms that result in oncogenic signaling KRAS mutant cells in support of drug discovery efforts. The Scientist I using primarily 3D cell culture systems will: 1) work to expand knowledge of RAS signaling pathways, 2) participate in experimental design and to independently conduct experiments in a priority-driven environment, 3) complete projects independently and as part of a team, 4) be responsible for timely updates of the project progress to their supervisor both informally and by formal report writing, 5) generate high-quality peer-reviewed publications, 6) be responsible for formal reporting of data including presentations and/or publications and, and 7) stay abreast of current research techniques and remain knowledgeable in pertinent areas through reading literature and by attending scientific presentations.

To learn more about the RAS Initiative at the Frederick National Lab, please visit: https://www.cancer.gov/research/key-initiatives/ras.
For information regarding Dr. Rachel Bagni, Sr. Scientist, Cancer Research Technology Program, and her lab, please visit: https://www.cancer.gov/research/key-initiatives/ras/screens-assays/model-development.

PLEASE NOTE THAT LEIDOS BIOMEDICAL RESEARCH, INC. CANNOT HIRE J-1 VISA HOLDERS FROM THE NATIONAL INSTITUTES OF HEALTH.

Qualifications:
To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:

PhD in a field related to pharmaceutical science, medicinal chemistry, or chemistry, or in a related discipline from an accredited college or university according to the Council for Higher Education Accreditation (CHEA) appropriate to biomedical research, or eight (8) years of experience in lieu of degree
Foreign degrees must be evaluated for U.S. equivalency
No experience required beyond the educational requirement
Knowledge of cell biology and signal transduction pathways
Ability to perform basic molecular biology experiments both independently and as a part of the RAS team in pursuit of specific research goals and objectives
Knowledge and ability to generate and characterize engineered cell lines used to study oncogenic signaling
Cell culture and cell-based assay development experience
Must be able to obtain and maintain a Security Clearance
Preferred Qualifications:
Candidates with these desired skills will be given preferential consideration:

Background in oncology and experience with in vitro cancer cell models
Experience with 3D cell culture model systems and 3D cell-based assays
Familiarity with the relevant scientific literature
Ability to develop and modify methods and techniques independently
To Apply:
If interested, please apply on-line for position #635379 at http://jobs.leidos.com/ShowJob/Id/1122950/Scientist-RAS-3D-Cell-Culture-(NCI)/


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Research Manager Malaria Global Health Lab

Date Posted:
3/22/2017

University of Maryland

MD

3/19/2017 Research Manager https://umb.taleo.net/careersection/umb_external_staff/jobdetail.ftl 1/3 This is the Jobs Portal for the UNIVERSITY OF MARYLAND, BALTIMORE | HUMAN RESOURCE SERVICES JOBS Job Description The University of Maryland, Baltimore (UMB), Division of Malaria Research (DMR) in the Institute for Global Health is currently seeking a Research Manager. The mission of the DMR is to support global malaria eradication efforts by developing and deploying innovative tools for improved malaria treatment, prevention and surveillance. Clinical and basic science research is supported domestically and throughout the regions with a high burden of malaria. This position is responsible for managing the operations of a research program and providing administrative and technical support to the research activities. This position is responsible for ensuring design, development, documentation and implementation of research procedures and protocols using a variety of complex activities. This position has the authority to formulate, affect, interpret, or implement management policies or operating practices. Benefits Information UMB offers a generous benefits package that includes 22 vacation days, 14 floating and holidays, 15 sick days; comprehensive health insurance and retirement options; and tuition remission for employees and their dependents at any of the University System of Maryland schools. Primary Duties and Responsibilities (Essential Functions) Manage research and administrative activities including training, scheduling, coordinating and delegating work, monitoring and evaluating performance to maximize effectiveness and productivity. Manage laboratory and staffing budget for grants from multiple sources. Create timelines and ensure that activities are being managed to meet key deadlines. Research Manager - (170000FP) 3/19/2017 Research Manager https://umb.taleo.net/careersection/umb_external_staff/jobdetail.ftl 2/3 Ensure quality control and safety compliance, develop policies and procedures, and order supplies for the lab. Identify and address issues and deficiencies and implement effective solutions. Manage the development and execution of project research studies. Revises studies, in consultation with upper management or principal investigator, to meet changing needs and requirements and enforces standards. Foster and support a conducive consultant/client environment, providing business unit and campus representatives with assessment, training, and advisement in research area. Creates a cohesive work team that works collaboratively to achieve unit’s goals. Oversees the recruitment, performance, and training of team members and continually reviews strengths and weaknesses of staff to maintain a well-trained, highly involved, and motivated team. Performs other related duties as assigned. Qualifications Education: Bachelor’s degree. Experience: Six (6) years of experience in research or project management including four (4) years in a relevant specialization. Supervisory: Two (2) years of direct supervision or responsibility for training, work coordination, and monitoring the work of others. Knowledge, Skills, and Abilities Strong writing skills for communications with team members, collaborators and sponsors. Ability to establish goals, structures, and processes necessary to implement a mission and strategic vision. Assumes personal responsibility for all outcomes; makes effective and timely decisions; and learns how to effectively use technology. Maintains productivity and uses knowledge strategies to increase knowledge base. Ability to perform basic accounting and statistical analysis. Ability to effectively communicate both verbal and written thoughts, ideas, and facts. Interprets and understands written information and is able to listen attentively to verbal and non-verbal cues that lead to a deeper understanding. Ability to maintain confidentiality of subjects and information obtained. Leadership, coaching, and team building skills to strengthen and cultivate relationships. Ability to network and interact, as well as support effective partnerships with key groups and individuals. Ability to work cooperatively with others and demonstrates professional, ethical, respectful, and courteous behavior when interacting with others. Demonstrate pleasant and positive interactions with other to meet customer expectations, and provide follow up with customers. Reaches compromise and consensus to influence and negotiate. Remains calm and is able to manage conflict, and works well with a diverse workforce. Approachable style allows others to be open in sharing thoughts and ideas. Able to make independent decisions that are a matter of significance for the unit. Hiring Range: Commensurate with education and experience 3/19/2017 Research Manager https://umb.taleo.net/careersection/umb_external_staff/jobdetail.ftl 3/3 Human Resource Services 410-706-7171 620 W. Lexington Street 3rd Floor Baltimore, MD 21201 The University of Maryland, Baltimore is an Equal Opportunity/Affirmative Action Employer. Minorities, women, protected veterans and individuals with disabilities are encouraged to apply. If accommodations are needed for a disability, please contact Staffing & Career Services at 410-706-2606, Monday – Friday, 8:30am – 4:30pm EST. Maryland Relay can be accessed by dialing 711 (in-state) or 1-800-735-2258. Equal Opportunity/Affirmative Action Employer. Minorities, women, protected veterans, and individuals with disabilities are encouraged to apply. Job Exempt Staff - E3327F Employee Class : Exempt Regular Full Time/Part Time: Full-Time Shift Day Job Financial Disclosure: No Organization Medicine Posting Date Mar 6, 2017 Unposting Date Mar 25, 2017, 11:59:00 PM © 2015-2016 UNIVERSITY OF MARYLAND, BALTIMORE. ALL RIGHTS RESERVED.


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Program Manager Global Health Malaria Research

Date Posted:
3/22/2017

University of Maryland

MD

3/19/2017 Program Manager - Institute for Global Health - Myanmar https://umb.taleo.net/careersection/umb_external_staff/jobdetail.ftl 1/3 This is the Jobs Portal for the UNIVERSITY OF MARYLAND, BALTIMORE | HUMAN RESOURCE SERVICES JOBS Job Description The Division of Malaria Research at the University of Maryland, Baltimore (UMB) Institute for Global Health seeks a Program Manager to ensure the success of the Maryland Global Initiatives Corporation (MGIC) program in Myanmar. The Program Manager will coordinate the daily activities of the program, staff functions, and manage budgetary issues. The Program Manager is responsible to set goals and create tactics in order to achieve programmatic objectives. This position hires and trains staff as needed. ***This position will require up to 10% travel to Myanmar.*** Benefits Information UMB offers a generous benefits package that includes 22 vacation days, 14 floating and holidays, 15 sick days; comprehensive health insurance and retirement options; and tuition remission for employees and their dependents at any of the University System of Maryland schools. Primary Duties and Responsibilities (Essential Functions) Plan and coordinate daily activities of the program in Myanmar including monitoring relationships of outside agencies or subcontractors. Work in collaboration with with senior management to develop, implement and achieve program goals and milestones. Supervise, train, schedule, and evaluate professional and clerical staff. Manage program budget, including approving finances, tracking expenditures, and preparing reports on current finances. Develop appropriate processes and procedures regarding research sample storage, monitoring, and transport between domestic and international sites. Program Manager - Institute for Global Health - Myanmar - (170000FO) 3/19/2017 Program Manager - Institute for Global Health - Myanmar https://umb.taleo.net/careersection/umb_external_staff/jobdetail.ftl 2/3 Ensure that administrative and regulatory requirements regarding human subject research are accurately met, documented, and reported. Coordinate and assist in training programs/capacity development workshops for employees, volunteers, and/or the community. Plan data management and communications strategy for the program. Assist in the coordination and communication between the US and local institutions and implementing partners. Perform other related duties as assigned. Qualifications Education: Bachelor’s degree in related field. Experience: Four (4) years experience in a related field. Supervisory: Two (2) years supervisor, program planning and coordination experience required. Knowledge, Skills, and Abilities Possesses knowledge of best practices in the field as well as all relevant federal, state, and local rules, regulations, and programs/policies for meeting compliance. Ability to establish goals, structures, and processes necessary to implement a mission and strategic vision. Skill in leadership, coaching, and team building in order to strengthen and cultivate relationships. Strategic and analytical thinking skills with an ability to solve problems and make decisions. Ability to prioritize ongoing and new projects, as well as conduct research and gather information. Skill in interpreting and understanding written information and is able to listen attentively to verbal and nonverbal cues that lead to a deeper understanding. Ability to operate current computer systems, including relevant software packages. Ability to prepare and analyze reports. Ability to create and manage a budget. Ability to perform statistical analysis. Ability to network and interact, as well as support effective partnerships with key groups and individuals. Ability to effectively communicate both verbal and written thoughts, ideas, and facts. Ability to schedule, train, supervise, assign work to, and evaluate staff. Ability to work cooperatively with others and demonstrates professional, ethical, respectful, and courteous behavior when interacting with others. Skill in demonstrating pleasant and positive interactions with other to meet customer expectations, and provide follow up with customers. Ability to reach compromise and consensus to influence and negotiate. Ability to remains calm, manage conflict, and works well with a diverse workforce. Hiring Range: Commensurate with education and experience If accommodations are needed for a disability, please contact Staffing & Career Services at 410-706-2606, Monday – Friday, 8:30am – 4:30pm EST. Maryland Relay can be accessed by dialing 711 (in-state) or 1-800-735-2258. Equal Opportunity/Affirmative Action Employer. Minorities, women, protected veterans, and individuals with disabilities are encouraged to apply. Job Exempt Staff - E1431F 3/19/2017 Program Manager - Institute for Global Health - Myanmar https://umb.taleo.net/careersection/umb_external_staff/jobdetail.ftl 3/3 Human Resource Services 410-706-7171 620 W. Lexington Street 3rd Floor Baltimore, MD 21201 The University of Maryland, Baltimore is an Equal Opportunity/Affirmative Action Employer. Minorities, women, protected veterans and individuals with disabilities are encouraged to apply. Employee Class : Exempt Regular Full Time/Part Time: Full-Time Shift Day Job Financial Disclosure: No Organization Medicine Posting Date Feb 28, 2017 Unposting Date Mar 19, 2017, 11:59:00 PM © 2015-2016 UNIVERSITY OF MARYLAND, BALTIMORE. ALL RIGHTS RESERVED.


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Instructor/Assistant Professor Malaria Immunology Research

Date Posted:
3/22/2017

University of Maryland

MD

3/19/2017 Instructor/ Assistant Professor- Institute for Global Health https://umb.taleo.net/careersection/umb_faculty+and+post+docs/jobdetail.ftl 1/3 This is the Jobs Portal for the UNIVERSITY OF MARYLAND, BALTIMORE | HUMAN RESOURCE SERVICES JOBS Job Description The Division of Malaria Research (DMR) within the University of Maryland School of Medicine’s Institute for Global Health (IGH) is recruiting for an Instructor or Assistant Professor, nontenure track, to design and lead clinical trials and epidemiological studies at the DMR’s international site in Malawi. Applicants with interest and qualifications to do so may also contribute to immunological, molecular and genomic aspects of DMR research studies. The faculty appointment will be at the rank of Instructor or Assistant Professor, nontenure track, based on guidelines for faculty appointment at the University of Maryland School of Medicine. The applicant will be expected to obtain a primary appointment in the Department of Pediatrics. This is a fulltime faculty position, preferably to be permanently located at the DMR clinical trials site in Malawi, Expatriate status . Since much of the proposed research involves studies in Malawi, prior experience in working in resource limited settings is strongly preferred. The successful candidate will have experience conducting clinical research, evidence of productivity as demonstrated by publication of completed projects and be interested in pursuing a career in scientific research. The Candidate will engage in collaborative research that draws upon the expertise of scientists from the Division of Malaria Research, the Department of Pediatrics, the Department of Epidemiology and Public Health and the Department of Microbiology and Immunology, affiliated international sites, and other strategic partnerships. Instructor/ Assistant Professor- Institute for Global Health - (170000JD) 3/19/2017 Instructor/ Assistant Professor- Institute for Global Health https://umb.taleo.net/careersection/umb_faculty+and+post+docs/jobdetail.ftl 2/3 Qualifications MD/PhD or PhD degree and appropriate postdoctoral experience in immunology Expertise in infectious diseases cellular immunology Experience supervising students and/or postdoctoral fellows PREFERRED CHARACTERISTICS: Experience in malaria or parasitology research Expertise in B cell immunology is highly desirable Experience conducting research using human field samples Proven success in obtaining research funding with some external funding in place Experience on research projects conducted in lowincome countries Track record of publications in peerreviewed journals The ability to work well in an interdisciplinary and multicultural team Excellent interpersonal skills and a willingness to work with others to overcome problems as and when they arise Ability to provide mentorship to junior colleagues and supervise MSc and PhD students and post –doctoral fellows Excellent written and spoken scientific communication skills For immediate consideration, please send a cover letter and uptodate CV, including names and contact information of three references, by email to: Nichole Harvey Gilliam, Institute for Global Health at the University of Maryland School of Medicine, 685 W. Baltimore St., HSF I, Room 480, Baltimore, MD 21201 nigilliam@som.umaryland.edu. Please reference position number 03314434 when applying. If accommodations are needed, contact Staffing & Career Services at 4107067171, Monday – Friday, 8:30am 4: 30pm EST. Maryland Relay can be accessed by dialing 711 (instate) or 18007352258. The University of Maryland, Baltimore is an Equal Opportunity/Affirmative Action Employer. Minorities, women, veterans and individuals with disabilities are encouraged to apply. 3/19/2017 Instructor/ Assistant Professor- Institute for Global Health https://umb.taleo.net/careersection/umb_faculty+and+post+docs/jobdetail.ftl 3/3 Human Resource Services 410-706-7171 620 W. Lexington Street 3rd Floor Baltimore, MD 21201 The University of Maryland, Baltimore is an Equal Opportunity/Affirmative Action Employer. Minorities, women, protected veterans and individuals with disabilities are encouraged to apply. Job Faculty Organization SOM Centers/Programs/ORCs Posting Date Mar 10, 2017 © 2015-2016 UNIVERSITY OF MARYLAND, BALTIMORE. ALL RIGHTS RESERVED.


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Assistant Professor Global Health Malaria Research

Date Posted:
3/22/2017

University of Maryland

MD

3/19/2017 Assistant/ Assoicate Professor-Institute of Global Health https://umb.taleo.net/careersection/umb_faculty+and+post+docs/jobdetail.ftl 1/3 This is the Jobs Portal for the UNIVERSITY OF MARYLAND, BALTIMORE | HUMAN RESOURCE SERVICES JOBS Job Description The Division of Malaria Research (DMR) within the University of Maryland School of Medicine’s Institute for Global Health (IGH) is recruiting for an Assistant or Associate Professor for malaria research in the area of immunology. Areas of focus can include but are not limited to infant and child immunity to malaria, HIVmalaria coinfection and interactions and the impact of the microbiome on immunological development and responses. Applicants with interest and qualifications to do so may also contribute to molecular and genomic aspects of DMR clinical research studies. The faculty appointment will be at the rank of Assistant Professor or Associate Professor, tenure track both of which will be considered, commensurate with experience and based on guidelines for faculty appointment at the University of Maryland School of Medicine. The applicant will be expected to obtain a primary academic appointment in the Department of Pediatrics. This is a fulltime faculty position based at IGH in Baltimore. The ideal applicant will have evidence of external research support that can be transferred to the institution. Mentored grants would be acceptable but independent funding is preferred. The successful applicant will be expected to establish and maintain a productive, externally funded research program within the Division of Malaria Research (DMR) and in close collaboration with the Immunology Group within the Center for Vaccine Development (the Division and Center are within the Institute for Global Health). The successful applicant will be expected to participate in collaborative research activities with other members of the DMR and to participate in academic and service activities based on standard policies at the University of Maryland School of Medicine. There will be opportunities for teaching and training graduate students, postdoctoral fellows and junior faculty. Assistant/ Assoicate Professor-Institute of Global Health - (170000JE) 3/19/2017 Assistant/ Assoicate Professor-Institute of Global Health https://umb.taleo.net/careersection/umb_faculty+and+post+docs/jobdetail.ftl 2/3 For immediate consideration, please send a cover letter and uptodate CV, including names and contact information of three references, by email to: Nichole Harvey Gilliam, Institute for Global Health at the University of Maryland School of Medicine, 685 W. Baltimore St., HSF I, Room 480, Baltimore, MD 21201 nigilliam@som.umaryland.edu. Please reference position number 03314434 when applying. Qualifications MD/PhD or PhD degree and appropriate postdoctoral experience in immunology Expertise in infectious diseases cellular immunology Experience supervising students and/or postdoctoral fellows PREFERRED CHARACTERISTICS: Experience in malaria or parasitology research Expertise in B cell immunology is highly desirable Experience conducting research using human field samples Proven success in obtaining research funding with some external funding in place Experience on research projects conducted in lowincome countries Track record of publications in peerreviewed journals The ability to work well in an interdisciplinary and multicultural team Excellent interpersonal skills and a willingness to work with others to overcome problems as and when they arise Ability to provide mentorship to junior colleagues and supervise MSc and PhD students and post –doctoral fellows Excellent written and spoken scientific communication skills If accommodations are needed, contact Staffing & Career Services at 4107067171, Monday – Friday, 8:30am 4: 30pm EST. Maryland Relay can be accessed by dialing 711 (instate) or 18007352258. The University of Maryland, Baltimore is an Equal Opportunity/Affirmative Action Employer. Minorities, women, veterans and individuals with disabilities are encouraged to apply. Job Faculty Organization SOM Centers/Programs/ORCs Posting Date Mar 10, 2017 3/19/2017 Assistant/ Assoicate Professor-Institute of Global Health https://umb.taleo.net/careersection/umb_faculty+and+post+docs/jobdetail.ftl 3/3 Human Resource Services 410-706-7171 620 W. Lexington Street 3rd Floor Baltimore, MD 21201 The University of Maryland, Baltimore is an Equal Opportunity/Affirmative Action Employer. Minorities, women, protected veterans and individuals with disabilities are encouraged to apply. © 2015-2016 UNIVERSITY OF MARYLAND, BALTIMORE. ALL RIGHTS RESERVED.


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Senior Scientist Biomedical Engineering

Date Posted:
3/17/2017

BD

MD

We are currently seeking a high-potential Senior Scientist with biological and engineering skills who can work within a multi-functional team to contribute to the development of automated solutions for the evolving clinical microbiology laboratory. Candidates for this lab-based position will have excellent skills in the design, execution, interpretation and presentation of laboratory experiments with minimal supervision and demonstrated learning agility. They will have excellent interpersonal and communication skills and enjoy working in a team environment. A basic understanding of product development and microbiology is desirable.

The successful candidate will work within the R&D microbiology team to develop, integrate and test diagnostic capabilities as part of an integrated automated platform for use in a clinical microbiology lab. In a team environment, she/he will work in the areas of specimen processing, pathogen detection, isolation, identification, and susceptibility testing of microorganisms in an automated environment, with responsibilities for the design and execution of experiments, maintaining technical data, data interpretation and generating reports. She/he will be required to communicate information and ideas clearly and effectively within a multidisciplinary group at various levels of the business.

Responsibilities:

Works cross-functionally with a number of disciplines and departments (microbiologist, chemists, engineers, marketing, service, etc. ) to develop concepts and designs to meet the needs of a clinical microbiology lab. +
Works with a development group to develop and/or test breadboard designs.
Collaboratively performs testing on prototype instruments and execute subsequent formal validations.
Develops protocols and experimental procedures to address issues or evaluate potential designs.
Writes reports, specification or documents related to these efforts.
Prepares procedures, write technical reports, publish research papers, and make recommendations based on their research findings. - Innovates novel concepts, approaches, and solutions for addressing clinical microbiology needs .
Conceives of and documents intellectual property within the scope of the role.
Engages in collaborative efforts with academic, hospital and other external organizations. May have responsibility for managing third-party relationships.
Participates in and contribute to other programs in the business as requested.
Requirements:

Bachelor’s degree required in the life sciences or biomedical engineering and 5 years related experience is required.
Candidates with an advanced degree are preferred. A PhD with postdoctoral experience is preferred.
Successful candidate will have a demonstrated aptitude for solving problems involving biological and instrumented or automated platforms.
Experience with data storage, processing and analysis is desirable.
The ideal candidate will have experience in a multidisciplinary development group with demonstrated communication and problem solving skills.
An aptitude for creative approaches to solving bio-mechanical problems is desired.
Primary Work Location

USA MD - Baltimore


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Senior Scientist Microbiology

Date Posted:
3/17/2017

BD

MD

Becton Dickinson is a world leader in pathogen identification and antimicrobial susceptibility testing in the clinical microbiology laboratory. We are currently seeking a high-potential individual with microbiology skills who can work independently and within a multifunctional team to contribute to the development of automated diagnostics solutions for the evolving clinical microbiology laboratory. The successful candidate will be an innovative biologist/microbiologist or biomedical engineer with a relevant life sciences background and demonstrated experience solving complex biological problems. The successful candidate will be able to effectively transition between manipulating biologicals, consumables and mechanical platforms. Candidates for this lab-based position will have excellent skills in the design, execution, data analysis and interpretation, and presentation of laboratory experiments with minimal supervision and demonstrated learning agility. They will have excellent interpersonal and communication skills and enjoy working in a team environment. A basic understanding of product development, particularly in a regulated clinical environment is desirable.
Job Description

Primary Duties and Responsibilities:

The successful candidate will work within the R&D microbiology team to conceive, develop, integrate and test diagnostic capabilities as part of an integrated automated platform for use in a clinical microbiology lab.

In a team environment, she/he will work in the areas of specimen processing, pathogen detection, isolation, identification, and antimicrobial susceptibility testing of microorganisms, with responsiblities for the design and execution of experiments, maintaining technical data, data analysis and interpretation, and generating reports. She/he will be required to communicate information and ideas clearly and effectively within a multi-disciplinary group at various levels of the business.

The primary responsibilities include:

Provides technical leadership and domain expertise in microbiology to cross-functional project teams aimed at the development of novel infectious disease diagnostics. Works closely with other functions (i.e., Marketing, Operations, Quality, Engineering R&D) to troubleshoot, characterize and resolve needs in existing and nacent technologies.
With minimal oversight, delivers hands-on lab-based experimental contributions toward programs or business objectives. Is highly learning agile, innovative and organized: proficient in executing multiple, simultaneous projects in a time-efficient manner. Independently provides data analysis and interpretation.
Maintains substantial current knowledge in relevant state-of-the art principles and technologies in clinical microbiology, microbial physiology, biochemistry and data analysis methods. Exercises and contributes to intellectual property and the scientific literature.
Collaboratively performs testing on prototype instruments and executes subsequent formal validations.
Develops protocols and experimental procedures to address issues or evaluate potential designs. Writes reports, specification or documents related to these efforts.
Prepares procedures, write technical reports, publishes research papers, and makes recommendations based on their research findings
Identifies clinical microbiology needs, and innovates novel concepts, approaches, and solutions for addressing those needs
Engages in collaborative efforts with academic, hospital and other external organizations. May have responsibility for managing third-party relationships.
May have personnel management responsibilities.
Required Education and Experience:

A minimum of a Bachelor’s degree in an appropriate field with at least 5 years of relevant Microbiology experience.
MS or PhD preferred.
The successful candidate will have a demonstrated aptitude for solving problems involving biological and instrumented platforms.
Experience with data storage, processing and analysis is desirable.


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Scientist I Antibody Development

Date Posted:
3/17/2017

MSD

MD

The Antibody Development Scientist will provide guidance for development and characterization of recombinant antibodies. The candidate will be responsible for, but not limited to: (1) analyzing and optimizing of antibody sequences; (2) phage display or other antibody display technologies; (3) screening antibodies for specificity; (4) functional testing of antibodies (5) development of purification and antibody handling procedures. The candidate will advise senior management on new techniques, methods, and strategies for making and improving recombinant antibodies. Independently designing and executing experiments, analyzing resulting data and presenting findings in a clear and concise manner will be among the principle responsibilities a Scientist is accountable for. Documentation duties will include keeping detailed records of experiments and product development, writing procedures, and preparing experimental summaries. This position may supervise the work of others directly and/or across interdisciplinary teams. The candidate must be able to manage several projects and coordinate between multiple groups. He/she must have excellent communication and interpersonal skills.

DUTIES AND RESPONSIBILITIES:

Bench Research/Hands-on laboratory work

Experiment planning and associated product documentation
Conduct experiments, analyze and critically review resulting data
Procure reagents and equipment
Understand and follow laboratory safety precautions and ensure compliance with company safety policies
May work with Biosafety Level 2 (BSL-2) materials such as viruses, bacteria and/or human clinical matrices (e.g. serum and plasma)
Participate in general lab maintenance
Computer/desk work

Prepare product documentation including summary reports
Troubleshoot and optimize experiments; communicate issues and solutions to managers
Write SOPs and assemble batch records
Present results to colleagues
Research new methods and train laboratory personnel
Cross-functional Coordination

Coordinate with other groups within the company
May manage and coordinate the activities of Research Associates
This may include a team of direct reports
Specific duties may vary depending upon departmental requirements

Requirements
EXPERIENCE AND QUALIFICATIONS:

 

Ph.D. in Life Sciences or related field
Minimum of two years laboratory experience with proven hands-on technical abilities
M.S. may be considered with additional years of experience
It is preferable to have a candidate with experience in recombinant antibody development.
The ideal candidate should have at least 3 years of experience in developing and optimization of recombinant antibodies with direct experience in phage display or related antibody display technologies
Excellent academic record and strong scientific fundamentals
Independent research experience
Industry experience is a plus
A demonstrated level of consistency in performance and aptitude for managing additional responsibility and accountability are required for next level consideration

KNOWLEDGE, SKILLS AND ABILITIES:

 

Strong scientific fundamentals and analytical background
Logical problem solving and demonstrated ability to organize and move project tasks forward in an orderly and structured fashion
Demonstrate ability to independently design and execute assay and reagent troubleshooting, optimization and validation experiments
Excellent oral, written communication and interpersonal skills are required
Effectively communicate issues/problems and results that impact timelines, accuracy and reliability of laboratory data
Effectively communicate performance goals and expectations
Proficiency in MS Office Suite
Experience with standard data analysis tools (Excel, GraphPad Prism) and the quantitative background to advance this knowledge on the job is expected
A wide degree of creativity and latitude is expected including the ability to multi-task in an environment with changing priorities


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Postdoc HIV

Date Posted:
3/17/2017

Duke

NC

The Duke Human Vaccine Institute (DHVI), an international leader in the fight against major infectious diseases, is currently recruiting for Postdoctoral Associates to join our research team. The Duke Human Vaccine Institute is an interdisciplinary, interdepartmental institute dedicated to the study of basic and translational science required to understand host-pathogen interactions that can be translated to vaccines against human diseases. Directed by Dr. Barton Haynes, we are a team of highly interactive investigators that have expertise in immunology, molecular biology, virology, microbiology, computational biology, and vaccine science. We are seeking highly motivated recent PhD graduates (Immunology, Molecular Biology, Biochemistry, Biomedical Engineering, Computational Biology, Virology or related scientific field) to play an integral role in the following projects related to HIV/AIDS Vaccines and Cure research and identification of correlates of protection for other diseases such as malaria:

• Identification of protective B cell responses through evaluation of HIV immunogens in animal models and in human vaccines. (Dr. Barton Haynes)
• Interrogate the biophysical properties of antibody-antigen binding interactions to provide insights into the mechanisms of protective immunity for HIV-1, malaria and other pathogens. (Dr. Georgia Tomaras)
• Assessment of immune-based strategies for prevention of maternal and pediatrics HIV/AIDS. (Dr. Sallie Permar)
• Investigate the development of HIV antibodies by analyzing immune repertoire sequencing and computationally design immunogens for human vaccines (Dr. Kevin Wiehe)

The DHVI has a dynamic mentoring program, directed by Dr. Georgia Tomaras, and our postdoctoral associates work in concert with Duke faculty and staff in an invigorating research training environment. One of our chief scientific missions is to support and train early stage investigators to be the next generation of scientific leaders equipped to identify and implement solutions for improving human health worldwide.

DHVI functions as not-for-profit vaccine development biotechnology enterprise, embedded within a top university. As a trainee within our mentoring program, you will interact with highly innovative and collaborative investigators and have the opportunity to master state of the art technologies. We are committed to providing an outstanding training environment and research experiences that will enhance your career. The education, expertise, initiative and dedication of the postdoctoral associates engaged in these projects will be important to the success of the studies. This is an opportunity to become part of a winning team that is working to discover novel ways to prevent infectious diseases.
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Bioinformatic Scientist

Date Posted:
3/17/2017

Gene Centric

NC

GeneCentric is seeking a Bioinformatics Scientist to join a growing team in Durham, North Carolina. GeneCentric is a biotech company developing novel cancer taxonomy diagnostics to facilitate more efficient drug development and improved patient care. The successful applicant will contribute to efforts developing novel computational tools for classification of tumors. He/She will support research activities and collaborative studies involving the use of complex algorithms for analysis of RNA and DNA sequence data and modeling to identify new associations. Ability to process raw sequencing data for variant identification and gene expression analysis, as well as skills for integrating diverse -omics data are required. Candidates with experience in the pharmaceutical industry are encouraged to apply.
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Job Requirements
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Qualifications and Skills Required
• Proficiency in the use of bioinformatics tools (e.g. GATK, BLAST, BWA, SAMtools, Freebayes, etc. ), file formats (e.g. FASTQ, BED, BAM, VCR), and publicly available databases (e.g. GEO, ClinVar, GenBank, Ensemble, COSMIC, OMIM, Annovar, dbSNP, etc.).
• Proficiency in transcriptome profiling, differential expression, and functional profiling (e.g., STARaligner, TopHat, CuffLinks, Bowtie, Kallisto, Blast2Go)
• Strong Unix skills and programming ability in at least one of the following: R, Python, Java, or Perl.
• Experience applying statistical models, Bayesian Networks, and performing hypothesis testing.
• Strong oral and written communication skills for presenting analysis results internally and externally required.

Education and Experience
• PhD degree in Bioinformatics, Genomics, Statistics, Biostatistics, Computational Biology, or equivalent, with a minimum of 3 years of relevant experience.
• Masters level candidates with at least 5 years of relevant experience may be considered if they have the required knowledge and experience.


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Lead Scientist Signal Transduction

Date Posted:
3/17/2017

KXT Bio

NC

Lead scientist sought to develop product portfolio focused on signal transduction cascades controlled by GTPases. KXTbio is a startup company with intellectual property used to monitor the activation of GTPases and their effectors. The successful candidate will be responsible for protein purification, assay optimization, and the development of new biochemical reagents. Ph.D. or equivalent required. Must have extensive laboratory experience in biochemistry or related discipline and excellent communication skills.

Excellent scientific and entrepreneurial opportunity for highly motivated individual.

Scientific independence and creativity also required. 50Kto 75K


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Scientist In Vivo Pharmacology

Date Posted:
3/17/2017

Sage Therapeutics

MA

AGE Therapeutics is searching for a creative, resourceful, integrative thinker for an important role that is responsible for managing in vivo pharmacology studies across Discovery and Development programs, applying knowledge of advanced principles, theories, and concepts in areas of expertise.

Roles and Responsibilities
Plans and ensures execution of laboratory research, with general guidance; investigates, selects, and/or develops new methods and technologies for project advancement; monitors work-flows to enable execution of studies.
Design and interpret in vivo pharmacology studies to evaluate the activities of small molecule drug candidates, investigate their mechanisms of action, and explore novel therapeutic hypotheses
Manage in vivo pharmacology research in a matrixed environment, as well as external academic collaborations and an extensive network of CROs
Prepare, review and deliver scientific presentations for internal/external use.
Maintains knowledge of state-of-the-art principles and theories, and applies this knowledge to the design, execution, and interpretation of experiments.
Contributes to the preparation of lucid scientific reports for projects teams; writes and reviews SOPs, contributes to scientific literature, conferences and publications.
Uses scientific knowledge and Sage’s policies and procedures to solve problems.
Plans own activities and weekly schedule with guidance in accordance with objectives and priorities.
Experience, Education and Specialized Knowledge and Skills

Must thrive working in a fast-paced, innovative environment while remaining flexible, proactive, resourceful and efficient. Excellent interpersonal skills, ability to develop important relationships with key stakeholders, good conflict management and negotiation skills, ability to analyze complex issues to develop relevant and realistic plans, programs and recommendations. Demonstrated ability to translate strategy into action; excellent analytical skills and an ability to communicate complex issues in a simple way and to orchestrate plans to resolve issues and mitigate risks.
Ph.D. in Neuroscience, Pharmacology, Biomedical Science or a scientific discipline with 0 - 3 years of relevant experience; or MS/MA with at least 5+ years of relevant experience; or BS/BA with at least 8+ years of relevant experience. A proven track record in progressing drug targets from validation to early clinical development is an asset.
Experience with conducting in vivo models of disease and evaluating pharmacological interventions.
Ability and willingness to work effectively in a highly collaborative, matrixed research environment.
Possess a strong attention to detail and have exceptional interpersonal, organizational and communication skills
Embrace our core values: Put People First, Do Big, Be Accountable, Grow through Learning and Change, and Work Fun
Excitement about the vision and mission of Sage


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Postdoc Molecular/Cell Biology

Date Posted:
3/17/2017

Syros

MA

Syros Pharmaceuticals is pioneering the understanding of the non-coding region of the genome to advance a new wave of medicines that control expression of disease-driving genes. Syros has built a proprietary platform to systematically and efficiently analyze this unexploited region of DNA in human disease tissue to identify and drug novel targets linked to genomically defined patient populations. Because gene expression is fundamental to the function of all cells, the Company’s gene control platform has broad potential to achieve profound and durable benefit across a range of diseases. Syros is focused on cancer and immune-mediated diseases and is advancing a growing pipeline, including its lead drug candidates SY-1425, a selective RARα agonist for genomically defined subsets of patients identified by its platform, for a range of cancers including acute myeloid leukemia and myelodysplastic syndrome, and SY-1365, a selective CDK7 inhibitor for a range of blood cancers and solid tumors. Led by a team with deep experience in drug discovery, development and commercialization, Syros is located in Cambridge, Mass.

Syros Pharmaceuticals is seeking an experienced Cell and Molecular Biologist to join a team of highly motivated scientists that are discovering new oncology drug targets and developing small molecule modulators of gene regulation.

The candidate must have a recent PhD in cell and molecular biology or related field. Experience in transcriptional regulation, epigenomics, drug discovery, oncology and familiarity with genome editing and genome-wide techniques are desired.

Responsibilities:

  • ?  Integrated data analysis and interpretation of genomic, epigenomic and transcriptional datasets

  • ?  Performance of next-generation epigenomic assays including ChIP-seq and RNA-seq

  • ?  Development of cell-based gene reporter models using CRISPR-mediated gene editing

  • ?  Biochemical isolation of transcriptional regulatory complexes

  • ?  High throughput chemical and CRISPR-based screening Requirements:

  • ?  Recent PhD degree in Cell Biology, Molecular Biology or related field with 2-5 years experience in transcriptional biology and epigenomics

  • ?  Familiarity with design and application of gene editing tools including CRISPR

  • ?  Standard molecular biology skills: DNA and RNA isolation, PCR, molecular cloning, transfection, protein isolation,

    cloning and immunodetection

  • ?  Experience with protein isolation and purification

  • ?  Strong attention to detail and the ability to handle multiple tasks

  • ?  Desire and ability to work in a fast paced, cross-functional, flexible and team-oriented environment

  • ?  Independent thinking, experimentation and analysis

  • ?  Strong interpersonal and written communications skills

    Candidates who are keen experimentalists, independent thinkers and enthusiastic team players that have a passion for drug discovery are encouraged to apply. Preference given to candidates with previous expertise in creating cell-based models through gene engineering, transcription factor biology and chromatin biology.


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Scientist/Senior Scientist Immunology

Date Posted:
3/17/2017

Syros

MA

Syros Pharmaceuticals is pioneering the understanding of the non-coding region of the genome to advance a new wave of medicines that control expression of disease-driving genes. Syros has built a proprietary platform to systematically and efficiently analyze this unexploited region of DNA in human disease tissue to identify and drug novel targets linked to genomically defined patient populations. Because gene expression is fundamental to the function of all cells, the Company’s gene control platform has broad potential to achieve profound and durable benefit across a range of diseases. Syros is focused on cancer and immune-mediated diseases and is advancing a growing pipeline, including its lead drug candidates SY-1425, a selective RARα agonist for genomically defined subsets of patients identified by its platform, for a range of cancers including acute myeloid leukemia and myelodysplastic syndrome, and SY-1365, a selective CDK7 inhibitor for a range of blood cancers and solid tumors. Led by a team with deep experience in drug discovery, development and commercialization, Syros is located

in Cambridge, Massachusetts.

Syros Pharmaceuticals is seeking a dynamic Cell Biologist/ Immunologist to join a team of highly motivated scientists that are using recent fundamental insights into transcriptional regulation to discover and develop novel medicines targeting gene control in cancer and autoimmunity.

The Scientist will participate with project teams in shaping the Immunology and Immuno-Oncology research strategy. The motivated individual will be responsible for cell assay development for new target identification and validation for Syros’ discovery and development teams. The successful candidate will have broad subject expertise including Immunology, Cell and Molecular Biology, and Cancer Biology. Expertise in immunological assays including multi-parameter FACS analysis of primary cells, ELISA, and cell differentiation/proliferation and tumor co-culture assays is required. In addition, the candidate should have expertise in design, execution, and interpretation of in vitro and in-vivo studies for target validation of potential drug targets in the autoimmune and immuno-oncology area. Previous work in immune-oncology biology is a plus.

Responsibilities:
-Provide scientific capabilities in the areas of immuno/oncology and autoimmunity to both preclinical discovery project and development project teams.

-Deliver critical project data internally and through a network of external study providers and collaborate with leading KOLs.
-Participate in biological selection and in vitro validation of novel drug targets
-Participate in discussions with project team biologists to define the appropriate dose & schedule for novel drug candidates in the chosen in vivo model; Practical understanding of PK/PD concepts in order to design in vivo studies for proof of concept is recommended.

- Work with project teams, external collaborators, and CROs, on existing programs and new drug target programs to design, operationalize, and interpret studies to validate potential drug targets in the area of autoimmunity and immuno-oncology

-Facilitate project transitions from Discovery to Preclinical Development in close collaboration with discovery, preclinical, and clinical/translational scientists.

620 Memorial Drive | Suite 300 | Cambridge, MA | 02139 | tel. 617.744.1340 | fax 617.744.1377

- Must be flexible and able to contribute to an evolving portfolio of projects spanning early discovery through preclinical stage.
-Clear communication and presentation skills are a requirement

Requirements:
Ph.D. in Immunology or Cell/Molecular Biology or equivalent area with at least 3 years of postdoctoral

training with a proven track record of publications in peer reviewed journals. Prior pharmaceutical industry experience is a plus.


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Senior Research Associate/Scientist Translational Biology

Date Posted:
3/17/2017

Syros

MA

Senior Research Associate/Scientist, Translational Biology

Syros Pharmaceuticals is pioneering the understanding of the non-coding region of the genome to advance a new wave of medicines that control expression of disease-driving genes. Syros has built a proprietary platform to systematically and efficiently analyze this unexploited region of DNA in human disease tissue to identify and drug novel targets linked to genomically defined patient populations. Because gene expression is fundamental to the function of all cells, the Company’s gene control platform has broad potential to achieve profound and durable benefit across a range of diseases. Syros is focused on cancer and immune-mediated diseases and is advancing a growing pipeline, including its lead drug candidates SY-1425, a selective RARα agonist for genomically defined subsets of patients identified by its platform, for a range of cancers including acute myeloid leukemia and myelodysplastic syndrome, and SY-1365, a selective CDK7 inhibitor for a range of blood cancers and solid tumors. Led by a team with deep experience in drug discovery, development and commercialization, Syros is located in Cambridge, Massachusetts.

Syros Pharmaceuticals is seeking an experienced Cell and Molecular Biologist to join a team of highly motivated scientists and clinical researchers in the translational medicine group, who are using recent fundamental insights into transcriptional regulation to discover and validate new oncology targets. This particular role will focus on gaining a deeper understanding of the effect of small molecules on model systems, including mouse studies, and helping to translate these insights in clinically actionable concepts in drugs that are moving forward into clinical development. The successful candidate will be expected to have a high degree of autonomy in designing and analyzing experiments with contributions toward presentations and publications in support of the project. These contributions will help guide the development of programs as they advance to the clinic and in the write up of scientific publications.

The candidate must have a PhD or 3-6 years of experience in academia or industry in maintaining human cell lines in tissue culture, familiar with use of small molecules in cancer biology including mechanism of action studies and must be proficient in standard molecular biology practices including RNA prep and qPCR. Experience with in vivo models of cancer and IHC based follow up is a plus. An interest in design and execution of experiment with a translational focus to support novel strategies in drug development is highly desirable.

Responsibilities:

  • ?  Performance of protein enrichment (IP) and ChIP-Seq experiments

  • ?  Determination of cell line sensitivities to gene regulation modulators

  • ?  Design and oversight of in vivo studies

  • ?  Tissue culture for cancer cell lines and primary samples

  • ?  Execution of overexpression and knockdown (shRNA/siRNA) experiments

  • ?  Detailed mechanism of action investigations

  • ?  Determination of target engagement from in vitro and in vivo samples

  • ?  qPCR and Western blot based expression quantitation of target genes

  • ?  Integrated data analysis and interpretation

    Requirements:

  • ?  BS or MS degree with 3-6 years of experience or PhD in Cell Biology or related field

  • ?  Basic molecular biology skills: DNA and RNA isolation, PCR, molecular cloning, protein processing and

    immunoblotting

  • ?  Familiarity with protein overexpression and knockdown strategies (RNAi and shRNA) in mammalian cells


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Senior Scientist, Molecular/Cell Biology

Date Posted:
3/17/2017

Syros

MA

Senior Scientist, Molecular/Cell Biology

Syros Pharmaceuticals is pioneering the understanding of the non-coding region of the genome to advance a new wave of medicines that control expression of disease-driving genes. Syros has built a proprietary platform to systematically and efficiently analyze this unexploited region of DNA in human disease tissue to identify and drug novel targets linked to genomically defined patient populations. Because gene expression is fundamental to the function of all cells, the Company’s gene control platform has broad potential to achieve profound and durable benefit across a range of diseases. Syros is focused on cancer and immune-mediated diseases and is advancing a growing pipeline, including its lead drug candidates SY-1425, a selective RARα agonist for genomically defined subsets of patients identified by its platform, for a range of cancers including acute myeloid leukemia and myelodysplastic syndrome, and SY-1365, a selective CDK7 inhibitor for a range of blood cancers and solid tumors. Led by a team with deep experience in drug discovery, development and commercialization, Syros is located in Cambridge, Massachusetts.

Syros Pharmaceuticals is seeking an experienced molecular/cell biologist to join a team of highly motivated scientists that are using recent fundamental insights into transcriptional regulation to discover and develop novel medicines targeting gene control.
The candidate must have a Ph.D. degree in Cell Biology, Biochemistry or a related discipline and have 4-6 years of productive post Ph.D. research experience proven by a strong record of achievement. Experience in the biotech/pharma industry preferred. This is a rare opportunity to join an exceptional start-up pushing the boundaries of drug discovery.

Responsibilities:

  • ?  Serve as biology project lead for small molecule drug discovery projects

  • ?  Investigate molecular mechanism of action of small molecules impacting transcriptional control using

    sophisticated transcriptomic and epigenomic analysis

  • ?  Integrate biological (e.g., CRISPR,shRNA) with compound mediated perturbation of cells to develop PD

    markers

  • ?  Use insights from mechanistic work to develop predictive markers for patient selection

  • ?  Execute integrated data analysis and interpretation in collaboration with computational biology group

  • ?  Prepare written documents to support regulatory submissions

  • ?  Initiate and develop external collaborations with external

  • ?  Present data in abstracts, posters, talks and peer-reviewed publications

    Requirements:

  • ?  Ph.D. in Cell Biology, Biochemistry or related field with 4-6 years of experience in testing and elucidating MOA

    of small molecules, preferably in industry

  • ?  Strong record of achievement (peer reviewed publications or regulatory documents)

  • ?  Familiarity with genetic and gene modulation techniques to analyze gene function

  • ?  Experience in genome wide transcriptional and epigenomic profiling

  • ?  Ability to extract insights from data rich experiments

  • ?  Familiarity in the design and execution of in vivo experiments

  • ?  Experience in writing and editing of reports suitable for IND submission

  • ?  Attention to detail and the ability to simultaneously handle multiple projects

  • ?  Desire and ability to work in a cross-functional and flexible team-oriented environment

  • ?  Strong interpersonal and strong verbal and written communications skills

    Candidates who are keen experimentalists, enthusiastic, creative and have a passion for drug discovery are encouraged to apply. Knowledge of cancer biology and transcriptional regulation is a plus.


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Senior Scientist Hematopoietic Stem Cells

Date Posted:
3/17/2017

Intellia

MA

COMPANY:

Intellia is developing therapeutic products to help people with genetic diseases. We apply CRISPR/Cas9 genome editing and gene therapy technologies to edit and restore genes to their normal, healthy sequence. We are a dedicated team driven to change patients’ lives. As we build our team, we’re excited to work with people who share our commitment and energy to making a difference.

SUMMARY:

We are looking for a Senior Scientist to join a growing team to execute on Intellia’s ex vivo programs, including engineering hematopoietic stem and progenitor cells with CRISPR/Cas9 to develop therapeutics for genetic disesase. The Senior Scientist will be involved in design and execution of an experimental plan to develop therapeutics for genetic diseases using hematopoietic stem cells. This unique role will place the successful candidate in a dynamic position as a key member of the team, interfacing regularly with company senior management and being involved in decision-making and in interactions with external stakeholders.

Develop disease specific therapeutic strategies including target identification, delivery systems and functional assays
Develop and optimize protocols for engineering cells using viral and non-viral vectors, including validation protocols
Design experiments, interpret data, and problem solve with a high level of independence and creativity to advance company’s cell therapy platform
Communicate research and development findings with internal and external partners.
Mentor and guide other scientists in the group as needed
REQUIRED SKILLS:

Strong understanding of and experience with human hematopoietic stem cell biology
Mouse xenotransplantation and/or mouse models of human disease
Demonstrated ability to identify, design, and drive innovative programs and demonstrated evidence of scientific “problem solving”.
Excellent time management and the ability to multi-task is essential
PREFERRED SKILLS and EXPERIENCE:

Experience working with viral and/or non-viral delivery systems.
Experience with cell cycle and/or DNA damage analysis.
Strong knowledge of gene editing is highly desired.
A detailed knowledge of stem cell, cellular and/or tumor immunology principles, technologies, and experimental techniques (cell culture, in vitro cellular assays, flow cytometry, etc…)
Demonstrated track record of successfully developing and employing in vitro/in vivo models
Demonstrated ability to lead and complete projects
Previous supervisory experience
QUALIFICATIONS:

Ph.D. with 2-6+ years of relevant experience in the field of stem cell biology.
Strong publication record related to cellular and molecular biology in the field of hematopoiesis
POSITION: Full-Time, Exempt

LOCATION: Cambridge, MA

EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.


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Computational Biologist

Date Posted:
3/17/2017

Intellia

MA

COMPANY:

The development of CRISPR/Cas9 gene editing technology opens a new frontier in biomedical research and clinical intervention. Adapted from a natural cellular process, CRISPR/Cas9 permits the editing of any gene in any organism with unprecedented simplicity and flexibility. Intellia Therapeutics was founded in 2014 by Caribou Biosciences and Atlas Venture, along with a consortium of leading scientists who have helped define the space. Intellia Therapeutics holds exclusive access to a broad intellectual property portfolio covering the application of CRISPR/Cas9 technology for human therapeutic use. As we build our team, we’re looking for people who share our commitment and energy to make a difference.

SUMMARY:

Intellia Therapeutics is seeking a computational biologist/bioinformatian to support the development of CRISPR/Cas9 based therapeutics. This position is an opportunity to contribute to diverse aspects Intellia's bioinformatics platform from the building pipelines for processing NGS data to analyzing downstream data.

RESPONSIBILITIES:

Develop and support NGS pipelines using commonly utilized tools (BWA, bowtie, samtools, etc)
Apply rigorous statistical methods for testing hypotheses on processed data
Implement and optimize databases and data storage methods
Work with scientists to develop computational methods and tools to support new assays and implement data analyses
Create scientifically rigorous visualizations, communications, and presentations of results
QUALIFICATIONS:

BS/MS with 2+ years experience or recent PhD in computational biology/bioinformatics or equivalent field
Demonstrated ability to write elegant and clean code in R, Python, Perl, or C++
Experience processing and analyzing biological data, especially sequencing data
Familiarity with Linux and shell scripting/bash


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Scientist I Biochemistry and Assay Development

Date Posted:
3/17/2017

Myokardia

CA

SUMMARY: Responsible for developing new assays and tools that enable mechanistic understanding of sarcomere modulators, as well as providing experimental support and direction for existing development strategies. Highly-motivated expert in sarcomere biology, biochemistry, and/or biophysics who can effectively communicate to diverse teams. Must possess strong desire to “lead from the bench” with creative, problem-solving mindset and keen ability to guide junior scientists.

 

ESSENTIAL DUTIES AND RESPONSIBILITIES:

Develop and validate both novel and established biochemical and biophysical assays to measure how potential therapeutic agents affect sarcomere function
Work with project teams to help guide lead optimization and build an effective bridge between in vitro biochemical modulation and in vivo effects on cardiac function
Collaborate with Cell Biology and Translational Science teams to create and design assays to link biochemical and biophysical assays to in vivo studies
Plan and perform critical-path experiments in a manner consistent with the timelines and objectives of therapeutic program teams
Contribute to pre-clinical and clinical reports/documents
Collaborate proactively and communicate effectively with multidisciplinary teams
Participate and present data at internal and external meetings

EDUCATION/EXPERIENCE/SKILLS:

Education:

Requires a PhD with 3+ years experience OR a Masters with 10+ years experience in biochemistry, biophysics, cell biology or related discipline sarcomere (deep knowledge of and experience working with the sarcomere of highest importance)

Requirements:

Minimum of 4+ years related experience; may include post-doctoral experience
Expert knowledge of enzyme kinetics, biophysical methods, and sarcomere biology/biochemistry/biophysics
Experience with collaborative participation in diverse team environments
Excellent verbal and written communication skills
Ability to delve into literature to define protocols, gain mechanistic insights, form testable hypotheses, and challenge existing assumptions
Reputation as emerging leader in sarcomere biology field with sustained performance with peer-reviewed publications and accomplishments to support this


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Scientist Phage Display UK

Date Posted:
3/17/2017

Agenus

INT

Overview:

We have an exciting opportunity for a Scientist with a background in Phage / Yeast display to join our team at our new site in Cambridge.
This is a state of the art facility located in the centre of Cambridge specialised in the development of biopharmaceuticals of Immuno Oncology targets.
You will be part of a global team, with opportunities to grow with the company.
Responsibilities:

Expected to independently carry out phage display / yeast display selections, from naïve selections and affinity maturation campaigns
Willingness to take the lead on programme teams as the “antibody expert”, to advise on antibody engineering aspects and to effectively select leads that will lead to genuine drug candidates
Aid in the building of new libraries, both practically and theoretically. Able to build affinity maturation libraries for key candidates
Expected to express and purify lead antibodies to small scale, and to conduct initial binding and biophysical screens. Able to work closely as part of team to make a decision on the best antibody candidates to take forward
Expected to give regular presentations, both internally and company wide
Manage all antibody data with the project and collate results
Laboratory based – is willing to take the lead within the laboratory and serve as subject matter expert
Is willing to supervise and mentor 1-2 scientific staff within the phage display group
Maintain a current and accurate laboratory record (lab notebook) of all activities
Qualifications:

MSc with >7 industrial experience or PhD in a biological science/biochemistry discipline. Experience in an industrial setting is desirable
Experience:
Experience in phage display, particularly with ScFv and/or Fab formats. Able to work independently in panning and selections of antibody formats for a variety of targets
Experience in yeast display would be an advantage
Able to identify and characterise lead clones from phage display campaigns using a variety of assays (RBA, ELISA, Biacore etc) in order to progress drug discovery programmes.
Must be project aligned and work effectively as part of a multidisciplinary team
Excellent molecular biology techniques: cloning, PCR, sequencing analysis.
Protein expression and purification on small scale required. Some experience in HTS expression and screening of antibodies would be advantageous
Experience with BIAcore and/or Luminex as tools to screen would be desirable
Experience with affinity maturation of antibody fragments using a variety of different techniques
Strong analytical and critical thinking skills with the ability to interpret complex data
Excellent written and verbal communication skills.
Ability to present data, both locally and company wide


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Scientist Cell Line Development UK

Date Posted:
3/17/2017

agenus

INT

Overview:

We have an exciting opportunity for a Scientist to join our new Cell Line Development Team in Cambridge.
This is a state of the art facility located in the centre of Cambridge specialised in the development of biopharmaceuticals of Immuno Oncology targets.
You will be part of a global team, with opportunities to grow with the company.



Responsibilities:

Conducting stable cell line development projects, including design, partial execution in timely manner, reporting to Molecule Project Teams.
Liaise and coordinate CLD projects with Process Development and Process Analytical groups.
Serve as Subject Matter Expert on Project Teams for early and late-stage projects.
Author and review documents in support of regulatory filings from IND/CTA to BLA.
Develop, evaluate and implement new technologies, methods and third party technology for process improvement.
Write working instructions or SOPs, technical reports and mentor junior staff.
Aid in the preparation and presentation of publications, presentations, regulatory documents and/or primary inventor of patents.
Liaise closely with collaborators and sites globally, maintain clear and efficient communication.
Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials, controlled drug, GxP compliance, where applicable.
Qualifications:

MSc with industrial experience (2-5 years) in relevant field or PhD in a biological science/biochemistry discipline.
Experience:
Experience in mammalian cell culture techniques (adherent and suspension cells, CHO, HEK) in various scales, from multi-wells to small scale bioreactors.
Experience in efficient transfections and selection of highly expressing stable cell lines, single cell cloning, evaluation of cell lines for productivity and product quality, cell banking. Experience with using FACS or ClonePix in developing monoclonal antibody expressing cell lines is a bonus.
Skills in molecular biology: construction of expression vectors, evaluation of expression and stability enhancing elements.
Experience with automation in cell line development and product analysis is highly desirable.
Experience with evaluation of cell line stability, both at the cell culture and genetic level.
Experience in an industrial setting is preferable.

Profile:
Ability to work autonomously and in a team.
Highly autonomous and productive in performing laboratory experiments or method development.
Outstanding organizational and multi-tasking skills; able to manage several projects/cell lines simultaneously.
Ability to effectively work on multiple project teams and changing project priorities.
Excellent writing and communication skills, good attention to details.
Supervise and mentor scientific staff as well as communicate effectively to senior management as appropriate.


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Ophthalmology Research Lead

Date Posted:
3/17/2017

Spark

PA

The Ophtalmology Lead will manage the Ophthalmology functional group within the Discovery Research group under Translational Research. He/she will be responsible for:
Providing leadership within a group of 2 to 3 scientists/research associates, to develop pre-clinical programs from early discovery to the clinic.
Initiate and oversee joint programs with academic collaborators.
Establishing project timelines and ensuring work is completed according to schedule.
Training and developing staff at varying levels of experience.
The Ophtalmology Lead position requires extensive translational experience with ocular gene therapies, including:
In-depth familiarity with target validation and lead identification/optimization, using a combination of molecular, cellular and in vitro/in vivo techniques for ophthalmic gene therapy.
Familiar with intraocular delivery techniques and have substantial experience with ophthalmic studies in laboratory animals.
In-depth knowledge of inherited retinal disorders is required. Some familiarity with AAV, as well as some knowledge of clinical trial design and regulatory strategy, is preferred.
RESPONSIBILITIES:
40% of the time
Hands-on execution of experiments on the bench
30% of the time
Identify and validate new indication targets. Design and trouble-shoot experiments based on personal experience and literature review. Prepare and deliver scientific presentations at internal and external meetings
10% of the time
Prioritize projects, plan workload, manage resource and personnel scheduling
10% of the time
Preparing sample analysis reports and write parts of regulatory submissions to FDA
10% of the time
Lead a team of scientists. Mentor and develop staff.
Ensure departmental goals and objectives are met and aligned to the broader organizational goals and objectives.
QUALIFICATIONS:
Extensive hands-on experience in ocular gene therapy, such as intravitreal and subretinal injections, pupillometry, etc.
Strong organizational skills.
Excellent writing and verbal communication skills.
Previous management experience preferred, but not required.
Strong publication record is a plus.
Experience with AAV vectors is a plus.
REQUIREMENTS:
Ph.D. in relevant scientific discipline (e.g. cell and molecular biology, biochemistry, etc.)
Minimum 5-8 years of hands-on experience in the field of ophthalmic gene therapy
Previous management or supervisory experience strongly preferred
WHO WE ARE:
Transforming Patient’s Lives. Spark Therapeutics is a pioneering gene therapy leader transforming the lives of patients suffering from debilitating genetic diseases by developing one-time, life-altering treatments. We are embarking on our goal to deliver the first approved gene therapy product in the US for genetic blinding conditions and have a product pipeline addressing other unmet rare genetic diseases. We have an entrepreneurial culture and are looking for talented and passionate professionals who are committed and motivated to making a difference in the lives of our patients. If you share our passion for excellence and are looking for a dynamic work environment that fosters creativity, scientific innovation and team collaboration, you may be a great fit for our team.

 


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Translational Research Lead Liver

Date Posted:
3/17/2017

Spark

PA

The Liver Lead will manage the Liver functional group within the Discovery Research group under Translational Research. He/she will be responsible for:

• Providing leadership within in a group of scientists/research associates, to develop pre-clinical programs from early discovery to the clinic.
• Initiate and oversee joint programs with academic collaborators.
• Establishing project timelines and ensuring work is completed according to schedule.
• Training and developing staff at varying levels of experience.

The Liver Discovery Research Lead position requires extensive translational experience with gene therapies targeting the liver, including:

• In-depth familiarity with target validation and lead identification/optimization, using a combination of molecular, cellular and in vitro/in vivo techniques for hepatic gene therapy programs.
• Familiar with delivery techniques targeting the liver and have substantial experience with studies in laboratory animals.
• Some familiarity with AAV, as well as some knowledge of clinical trial design and regulatory strategy, is preferred.

RESPONSIBILITIES:
Hands-on execution of experiments on the bench
Identify and validate new indication targets. Design and trouble-shoot experiments based on personal experience and literature review. Prepare and deliver scientific presentations at internal and external meetings
Prioritize projects, plan workload, manage resource and personnel scheduling
Preparing sample analysis reports and write parts of regulatory submissions to FDA
Lead a team of scientists. Mentor and develop staff.
Ensure departmental goals and objectives are met and aligned to the broader organizational goals and objectives.
EDUCATION and EXPERIENCE REQUIREMENTS:
Ph.D. in relevant scientific discipline (e.g. cell and molecular biology, biochemistry, etc.)
Minimum 5-8 years of hands-on experience in the field of gene therapy.
Previous management or supervisory experience strongly preferred.
KEY SKILLS, ABILITIES and COMPETENCIES:
Extensive hands-on experience in hepatic gene therapy techniques, such as intravenous injection, hepatocyte isolation, etc.
Strong organizational skills.
Excellent writing and verbal communication skills.
Previous management experience preferred, but not required.
Strong publication record is a plus.
Experience with AAV vectors is a plus.
COMPLEXITY and PROBLEM SOLVING:
Demonstrate independent problem solving skills of technical issues; develop solutions to a variety of moderate to complex problems. Discuss with supervisor and refer to policies/practices for guidance.
Must be comfortable in the fast-paced, biotech start-up environment and interact with multi-disciplinary research teams at Spark.
Exercise judgment within defined procedures and practices to determine appropriate action.
INTERNAL and EXTERNAL CONTACTS:
Quality Assurance, Clinical Operations, Pharm/Tox, Discovery, Assay Development, R&D Operations, Technical Operations, Regulatory Affairs, Executive Team.

WHO WE ARE:
Transforming Patient’s Lives. Spark Therapeutics is a pioneering gene therapy leader transforming the lives of patients suffering from debilitating genetic diseases by developing one-time, life-altering treatments. We are embarking on our goal to deliver the first approved gene therapy product in the US for genetic blinding conditions and have a product pipeline addressing other unmet rare genetic diseases. We have an entrepreneurial culture and are looking for talented and passionate professionals who are committed and motivated to making a difference in the lives of our patients. If you share our passion for excellence and are looking for a dynamic work environment that fosters creativity, scientific innovation and team collaboration, you may be a great fit for our team.

 


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Translational Research Lab Manager

Date Posted:
3/17/2017

Spark

PA

Manage the day to day technical operation of the translational lab, inclusive of: assay development, pharmacology & toxicology, and discovery research.
Champion all safety aspects in the Translational Laboratories.
Implement and manage an inventory system for biological reagents (plasmids, cells, vectors) and co-ordinate reception and shipment of reagents.
Train and assist technical staff in the performance of laboratory experiments ensuring work is completed according to project time lines.
Responsible for short and long term planning for all aspects of lab operations, maintaining focus on scientific goals of the pipe line programs.
Oversee and manage the day-to-day operations of our external vivarium vendor.
Ensuring adequate personnel, space, equipment, and facilities remain available.
Coordinate the work load in collaboration with other department leads.
RESPONSIBILITIES:
Independently design, determine techniques and perform experiments on the bench.
Mentor and develop staff. Train and assist technical staff in the performance of laboratory experiments. Responsible for all safety aspects and best practices, and employee training.
Ensure departmental goals and objectives are met and aligned to the broader organizational goals and objectives.
Prioritize and plan projects and workloads, manage resources and personnel scheduling.
Coordinate and align centralized lab management efforts across assay development, pharmacology, toxicology and discovery research.
Short and long term planning of lab operations
Oversee and manage the day-to-day operations of our external vivarium vendor
Implement and maintain Spark Translational inventory system
Supplier & Vendor Management and negotiations
Manage translational research samples and materials
EDUCATION and EXPERIENCE REQUIREMENTS:
Bachelor’s degree required; PhD in a relevant field preferred.
Minimum of 5-8 years of strategic and hands-on laboratory experience.
Previous management or supervisory experience strongly preferred.
Broad understanding of the technical and equipment needs in a lab as well as extensive hands-on experience with standard molecular and cell biology techniques such as DNA cloning, qPCR, ELISA, flow cytometry, cell culture, etc.
Experience with AAV vectors is a plus.
KEY SKILLS, ABILITIES and COMPETENCIES:
Strong organizational skills.
Excellent writing and verbal communication skills.
Demonstrated ability to effectively manage performance and talent.
COMPLEXITY and PROBLEM SOLVING:
Demonstrate independent problem solving skills of technical issues; develop solutions to a variety of moderate to complex problems; Discuss with supervisor and refer to policies/practices for guidance.
Must be comfortable in the fast-paced, biotech start-up environment and interact with multi-disciplinary research teams at Spark.
Exercise judgment within defined procedures and practices to determine appropriate action.
INTERNAL and EXTERNAL CONTACTS:
Quality Assurance, Clinical Operations, Pharm/Tox, Discovery, Assay Validation, R&D Operations, Technical Operations, Regulatory Affairs

 

WHO WE ARE:
Transforming Patient’s Lives. Spark Therapeutics is a pioneering gene therapy leader transforming the lives of patients suffering from debilitating genetic diseases by developing one-time, life-altering treatments. We are embarking on our goal to deliver the first approved gene therapy product in the US for genetic blinding conditions and have a product pipeline addressing other unmet rare genetic diseases. We have an entrepreneurial culture and are looking for talented and passionate professionals who are committed and motivated to making a difference in the lives of our patients. If you share our passion for excellence and are looking for a dynamic work environment that fosters creativity, scientific innovation and team collaboration, you may be a great fit for our team.

 


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Ocular Research Scientist

Date Posted:
3/17/2017

Spark

PA

The Ocular Research Scientist is a member of the Ocular functional group within Translational Research.

He/she will be responsible for:
Design, execution and data analysis for ocular-directed research programs.
Write study reports, manuscripts and present results at appropriate scientific meetings.
Initiate and oversee joint programs with external collaborators.
RESPONSIBILITIES:
Hands-on execution of in vitro and in vivo experiments on the bench.
Identify and validate new indication targets and evaluate gene expression cassettes to support both existing and new programs in the pipeline. This includes executing experiments on the bench, extensive literature review, championing product candidate development from proof of concept to IND submission, etc.
Prepare sample analysis reports and write parts of regulatory submissions to regulatory agencies.
QUALIFICATIONS:
Strong organizational skills.
Excellent writing and verbal communication skills.
REQUIREMENTS:
Ph.D. in relevant scientific discipline required (e.g. cell and molecular biology, biochemistry, etc.)
Minimum 2-3+ years of hands-on research experience with gene therapies targeting the eye.
In-depth familiarity with target lead identification/optimization using a combination of molecular, cellular and in vitro/in vivo techniques for ocular gene therapy programs.
Experience with delivery techniques targeting the eye (subretinal and intravitreal injections).
Experience with studies in laboratory animals.
Experience with AAV vectors is required.
Molecular biology proficiency is required.
Strong publication record is a plus.
Extensive hands-on experience in ocular gene therapy in animal models, such as intravitreal and subretinal injections, pupillometry, ERG, OCT, etc.
WHO WE ARE:
Transforming Patient’s Lives. Spark Therapeutics is a pioneering gene therapy leader transforming the lives of patients suffering from debilitating genetic diseases by developing one-time, life-altering treatments. We are embarking on our goal to deliver the first approved gene therapy product in the US for genetic blinding conditions and have a product pipeline addressing other unmet rare genetic diseases. We have an entrepreneurial culture and are looking for talented and passionate professionals who are committed and motivated to making a difference in the lives of our patients. If you share our passion for excellence and are looking for a dynamic work environment that fosters creativity, scientific innovation and team collaboration, you may be a great fit for our team.

 


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Biomedical Engineer - Device Design and Development

Date Posted:
3/17/2017

Semma

RI

Semma Therapeutics, a recently founded biotechnology company focused on developing a stem cell-based cell therapy for Type 1 diabetes, is seeking a scientist to join its growing team. The full-time role will focus on developing, evaluating, and fabricating novel biomaterials for use in encapsulation systems that enable clinical evaluation of Semma’s core cell technology. The candidate will have a strong background in biomedical and chemical engineering, and will possess micro- and / or nano-fabrication skillsets to be used in developing processes used in the manufacture of implantable devices. A working knowledge of GLP / GMP systems is desired as well as preclinical development experience.

Under the supervision of the Director of Device Development, the scientist will also be expected to play an integral role in manufacturing validation. The position will be located in Providence, RI.

Required qualifications:

MS or PhD in biomedical engineering, chemical engineering, or related discipline
Medical device manufacturing experience
Experience working in a cleanroom environment
Demonstrated translation of research into defined processes and associated SOPs
Exhibits capability in planning, executing, and analyzing experiments
Able to troubleshoot, solve difficult problems, and develop process improvements
Attention to detail and careful record-keeping
Excellent organizational skills and ability to manage multiple projects
Excellent oral and written communication skills, able to write technical reports and protocols
Flexible team player excited to collaborate with internal and external partners
Highly self-motivated
Flexibility in working schedule to accommodate weekend work
Preferred qualifications:

Experience in evaluating biomaterials in animal models
Previous experience and knowledge of pancreatic islet biology and diabetes
Experience in regulatory submissions


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Pre Clinical Biology Scientist Neuroscience Epilepsy

Date Posted:
3/17/2017

Ovid

NY

Ovid’s pipeline is expanding rapidly, necessitating growth of the research team. This incoming scientist will work with contract research organizations, and in some instances academic collaborators, to test specific experimental hypotheses relating to in-house assets. Extensive hands-on experience carrying out neuroscience research is essential. This background will enable:

RESPONSIBILITIES

Rapid familiarization with disease related literature and appropriate model systems
Development of appropriate detailed research protocols (in collaboration with internal research team and external parties)
Day to day oversight of external activities and progress
Interpretation and communication of results to the internal team
REQUIREMENTS

Extensive hands on experience carrying out neuroscience research, either in an academic or industry setting, is a must. She or he should have an MSc or preferably a Ph.D. in biochemistry, molecular biology, neuroscience or a related field. Expertise in electrophysiological research techniques and a background in pediatric epilepsies is highly desirable.

The successful candidate will be internally motivated, comfortable working independently, and strive to proactively mitigate risks. The desire to be in a rapidly changing start-up environment is also necessary.

CONTACT

Kristen Alexander | Talent Acquisition & Engagement | Ovid Therapeutics kalexander@ovidrx.com

 


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Scientist/Sr. Scientist Immunooncology

Date Posted:
3/17/2017

CRIPSR

MA

Scientist / Sr. Scientist, Immuno-Oncology

If interested and qualified, please include Requisition # 2017-106 in the subject line when emailing resume to: careers@crisprtx.com.

For more information on CRISPR Therapeutics, please click here.

Position Summary

We are seeking a Scientist who will lead efforts in developing novel CRISPR-based therapeutics for oncology. The successful candidate will help build a pipeline of immuno-oncology products and will have expertise in biologic therapeutics in oncology as well as an understanding in immunology. The position requires enthusiasm, passion, attention to detail, and a commitment to improve the lives of those afflicted with cancer.

Responsibilities

Establish a pipeline of CRISPR-based therapeutics for oncology including CAR T based therapies
Conceive, design and perform experiments
Collaborate with and serve as scientific mentor to assigned Research Associates, directing the work of Research Associates at the laboratory bench as necessary
Assist company in securing IP from research program discoveries, including detailed descriptions for patent filing and/or proof of concept work, as appropriate appropriate
Minimum Qualifications

PhD in a related scientific discipline and with 0-3 years of postdoctoral experience
Experimental knowledge of immune cells, particularly in the functional characterization of T cells
Experience with antibody engineering
A strong track record of intellectually challenging oneself to enhance scientific capabilities
Scientifically rigorous, highly organized, and with significant attention to detail
Excellent oral and written communication skills
Ability to work independently as well as collaborate with peers and effectively work in a results oriented research team environment
Preferred Qualifications

Knowledge of the pathophysiology and treatment of cancer
High energy level, focus, a passion and sense of urgency for developing important new medicines for devastating diseases
Competencies

Problem Solving – The ability to understand a situation, task or problem by breaking it down into smaller pieces using a systematic approach and to identify patterns and connections between situations that are not obviously related.
Scientific Rigor/Attention to detail – Maintains high scientific rigor and attention to detail in designing and testing hypotheses and analyzing data. Challenges assumptions, demonstrates highly organized thinking and documentation.
Creativity/Innovation – Creates a boundary-less environment that fosters curiosity and taking risks, is able to test, confirm or refute scientific hypothesis effectively and efficiently. Open to new approaches, alternative points of view and methodologies. Able to be opportunistic.
Leadership – The ability to take the role as a leader of a team or work group.
Communication and Teamwork – Effectively expresses ideas in written, visual, and oral context. Able to work co-operatively with others; the genuine desire to be a part of a team and contribute to organizational and team goals.
Passion – Creates an exciting environment where there is a true passion for the vision of CRISPR Therapeutics to bring novel medicines to patients suffering from serious diseases.
If interested and qualified, please include Requisition # 2017-106 in the subject line when emailing resume to: careers@crisprtx.com.

 


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Computational Biology Scientist

Date Posted:
3/17/2017

CRISPR

MA

Computational Biology Scientist

If interested and qualified, please include Requisition # 2017-107 in the subject line when emailing resume to: careers@crisprtx.com.

For more information on CRISPR Therapeutics, please click here.

Position Summary

We are seeking a talented Computational Biologist / Bioinformatics Scientist to tackle challenging bioinformatics and computational biology problems and work collaboratively with research groups to build the tools, algorithms, and pipelines required to support the development of new, transformative CRISPR/Cas9-based gene editing therapies.

Responsibilities

Develop and implement computational biology tools and programs to support all gene editing and research activities
Balance integration and extension of existing bioinformatics and next generation sequencing tools with the creation of new tools and algorithms as dictated by projects and problem contexts
Design and code web tools for data analysis and integration in close interaction with researchers and with a strong focus on the researchers’ needs
Produce high-quality code that is optimized for performance and scalability and adherence to coding best practices
Help identify test cases, resolve issues, and fix bugs
Give accurate time estimates based on verbal and written specifications
Minimum Qualifications

Degree (Ph.D. or equivalent) in quantitative or basic science (computer science, computational biology / bioinformatics, chemistry, physics, mathematics, or applied science preferred)
Experience (new graduate or post-doc) with background in creating, managing, analyzing genome scale data and / or tools as for example: microarray or next generation sequencing (NGS) including whole genome, exome, RNA-seq, ChIP-seq, methylation sequencing (RRBS)
A solid grasp of R and/or Python is essential for success with other languages such as Java, C++, MATLAB also helpful
Ability to work independently and successfully in a matrix environment, prioritize and manage multiple tasks simultaneously, integrate cross-functional issues and balance competing priorities effectively
Good writing skills including documentation skills to maintain software and support documentation
Preferred Qualifications

Advanced degree (Ph.D., or equivalent) or significant work experience (0-2 years’ experience)
The ideal candidate will be a software engineer or computational biologist that can think from the point of view of a biologist while understanding computer science / software engineering at a deep level; very close interaction with molecular / cell biologists will be expected at every level from tool / algorithm design, curation / quality control, analysis, and code testing to ultimately delivering algorithms and tools (Bioinformatics Software Engineer) or insights and recommendations (Computational Biologist) to other researchers and decision makers
Wide understanding of both biology and computational biology
Experience working in fast paced team environments (industry and start-up experience is a plus)
Ability to understand and make decisions and recommendations about high level strategy as well as about the details of an analysis project or experiment
Extensive experience in bioinformatics, software engineering / testing / validation, data curation, large scale data and NGS analysis, statistics, or statistical model building, as evidenced by productive and successful programs and/or publications
Experience with Git, R Markdown / LaTeX
Cloud compute experience (AWS)
Strong leadership and management skills, excellent verbal and written communication
Familiarity with cell and molecular biology techniques, NGS, gene editing and/or CRISPR/Cas9 biology
A high degree of energy, accuracy and attention to detail, and a passion for creating transformative gene-based medicines to patients with serious diseases
Competencies

Approachability – Is easy to talk to, builds rapport well, and makes extra effort to put others at ease.
Listening – Practices active, patient listening. Has the ability to restate and consider a differing view, even when not in agreement.
Problem Solving – The ability to understand a situation, task or problem by breaking it down into smaller pieces using a systematic approach and to identify patterns and connections between situations that are not obviously related.
Creativity/Innovation - creating a boundary-less environment that fosters curiosity and taking risks, openness to new approaches, diversity of new thought, blank page creativity and opportunistic thinking.
Perseverance – Pursues tasks with energy, drive and initiative, even in the face of adversity.
Results Oriented – Drives issues to closure and gets the job done.
Communication and Teamwork – The ability to effectively express ideas in written and oral context. The ability to work cooperatively with others; the genuine desire to be a part of a team and contribute to organizational and team goals.
If interested and qualified, please include Requisition # 2017-107 in the subject line when emailing resume to: careers@crisprtx.com.

For more information on CRISPR Therapeutics, please click here.


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Postdoc GENIE

Date Posted:
3/17/2017

HHMI

VA

Janelia Research Campus (Janelia) supports large, multidisciplinary projects in neurobiology and imaging. The GENIE (Genetically-Encoded Neuronal Indicator and Effector) project produces thousands of molecular constructs per year, with the goal of creating highly sensitive calcium and voltage indicators, to increase the sensitivity and resolution of imaging and analysis of functional neural systems. Constructs are screened in tissue culture assays. Promising candidates are then calibrated and tested in vivo in transgenic Drosophila and other model systems.

The Research Specialist will be a hands-on independent researcher, responsible for taking promising hits from earlier phase screening efforts, characterizing their performance and potential toxicity in vivo in Drosophila larvae and adults, and correlating sensor signals with electrophysiological recordings using electrical and/or sensory stimulation.



Essential Duties and Responsibilities:

Perform in vivo optical imaging in Drosophila larval neuromuscular junction (NMJ) using fluorescence microscopy. Stimulate activity at the NMJ using suction electrodes and use statistical analysis to correlate resulting sensor signal with action potentials.
Perform simultaneous optical imaging and electrophysiology in the central brain of intact adult flies under sensory stimulation. Test sensor effects on normal responses of identified neurons, and correlate sensor signal with action potentials recorded using patch clamp recordings.
Modify biological preparation, instrumentation and analysis routines as necessary to test calcium and voltage indicators.
Perform other related duties as required.


Scope:

Will not have personnel management responsibilities.


Preferred Qualifications:

Education / Experience:

Ph.D. or M.S. in Neuroscience, Biophysics, or related discipline.
5 years experience with fluorescence microscopy and analysis techniques. Two-photon microscopy experience a plus.
Demonstrated experience with intracellular electrophysiology. Patch clamp recording experience a plus.
Significant experience with larval or adult fly physiology.
Data analysis skills (proficiency in MATLAB or similar analysis environment preferred).
Excellent communication skills.

Skills and Abilities:

Ability to perform extensive hands-on work at the bench, with minimal supervision.
Ability to fully document and substantiate scientific methods, procedures, and results.
Ability to manage and analyze large data sets.
Computer skills for image and statistical analyses, document preparation, database management, and presentations.

Physical Requirements:

Occasionally lifts and/or carries objects weighing up to 20 pounds.
Occasionally stoops and bends.
Occasionally reaches and grasps with arms and hands.
Work involves possible exposure to malodorous vapors, animal allergens and other animal-borne hazards, experimental microbial agents, low dose radiation, contamination by toxic chemicals and acids and presence of carcinogenic substances.
Long periods of standing and/or sitting.
Job Location
Ashburn, Virginia, United States
Position Type
Full-Time/Regular


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Research Specialist or Postdoc MultiFISH

Date Posted:
3/17/2017

HHMI

VA

Howard Hughes Medical Institute (HHMI) is a science philanthropy whose mission is to advance biomedical research and science education for the benefit of humanity. We empower exceptional scientists and students to pursue fundamental questions about living systems, and work to share scientific discoveries with researchers, students, and science-curious individuals around the world.

Founded in 1953 by aviator and industrialist Howard R. Hughes, HHMI is headquartered in Chevy Chase, Maryland, and employs more than 2,500 people across the U.S. Visit hhmi.org/careers to learn more about working at HHMI.

About Janelia
Janelia Research Campus is a pioneering research center in Ashburn, Virginia, where scientists pursue fundamental questions in neuroscience and imaging. The Howard Hughes Medical Institute (HHMI) launched Janelia in 2006, establishing an intellectually distinctive environment for scientists to do creative, collaborative, hands-on work. The Janelia Research Campus is a unique, world-class research institute with a major focus on the development of cutting-edge imaging and analysis tools. We prize collaboration and in addition to supporting independent laboratories, we support a unique ecosystem of Project Teams to tackle experimentally challenging problems at scale. To learn more about working at Janelia, visit janelia.org/careers.

Summary
The Howard Hughes Medical Institute's Janelia Research Campus is looking for an outstanding Research Specialist or Postdoctoral Associate interested in developing new methods for highly multiplexed imaging of RNA in neural tissue, using the Expansion Microscopy technique for physically expanding tissue by embedding in a swellable gel. The MultiFISH project team is a new effort to combine new molecular and imaging methods in order to develop a robust protocol for multiplexed RNA Fluorescence In Situ Hybridization (FISH). This protocol will be made readily available to research groups at Janelia and in the broader neuroscience community. The broader goal is to enable studies that combine in vivo experiments with post-fixation molecular characterization of the same tissue. We seek a candidate interested in developing new methods and helping to develop a robust protocol including tissue handling, probing, and imaging. This is a highly collaborative position with opportunities to interact with the Tillberg, Sternston, Svoboda and Lavis Labs. Individuals interested in pursuing an academic research career or a specialist with experience in histology and/or optical imaging are encouraged to apply.

Principal Responsibilities:
Develop cutting edge hydrogel tissue embedding methods.
Carry out RNA Fluorescence In Situ Hybridization (FISH), high content imaging, and spectral unmixing in thick brain tissue slices.
Work collaboratively with a team of scientists to develop a protocol for multiplexed RNA FISH in thick tissue slices suitable for routine use in neuroscience experiments.

Preferred Qualifications:
PhD in Engineering, Bioengineering, Biology, Neuroscience or a related discipline
Strong background in optical imaging and image processing using large imaging datasets
Experience with RNA Fluorescence In Situ Hybridization (FISH) useful but not necessary
Ability to work as part of a team
Ability to develop novel approaches


HHMI is an Equal Opportunity Employer.
Job Location
Ashburn, Virginia, United States


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Research Specialist I metabolomics

Date Posted:
3/17/2017

HHMI

TX

Dr. Sean J. Morrison, HHMI Investigator and Director of the Children’s Research Institute at the University of Texas Southwestern Medical Center (CRI) invites applications for RESEARCH SPECIALIST positions to apply metabolomics methods to the study of stem cell metabolism.

We seek scholars with Ph.D. or equivalent degrees and demonstrated scientific accomplishment, who exhibit the potential to perform outstanding research in metabolomics. The primary responsibility of the Research Specialist will be to develop and implement metabolomic profiling methods using an AB SCIEX 5500 QTRAP LC/MS/MS and an Agilent 6550 iFunnel Q-TOF LC/MS. Applicants should have experience with method development, including preparation of biological samples, chromatographic separation, mass spectrometry and data analysis. Key ongoing projects using the facility involve analyzing the abundance and isotopic enrichment of informative metabolites in human plasma, tumor tissue and primary hematopoietic stem cells from mice. NMR spectroscopy, 13C dynamic nuclear polarization and a state-of-the-art mouse metabolic core facility are also available on campus to complement metabolomics studies and to provide an unparalleled breadth of metabolic analysis.

Applicants should provide a curriculum vitae, a one page summary of research experience, and a list of references when submitting the online application.


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Research Specialist I

Date Posted:
3/17/2017

HHMI

WI

Job Description
At the Howard Hughes Medical Institute (HHMI), creativity and excellence are fundamental to our success. As one of the world's largest philanthropies, HHMI is a major force in advancing biomedical research and science education in the U.S. and beyond.
Perform professional work in support of scientific research. Working collaboratively with the Investigator, determine the most suitable methods to be used in research. Independently perform scientific investigative procedures requiring application of professional judgment. Interpret experimental results and determine whether they are consistent with experimental goals. Review pertinent literature for information that will further research goals. Prepare reports of research for presentation or publication.
Required Skills
Perform various specialized scientific investigative procedures in support of assigned research projects.
Develop transgenic technologies for planarian flatworms.
Generate gene knock-outs and knock-in reporter lines.
Independently design and conduct experiments under the supervision of Principal Investigator.
Conduct literature reviews to be used in determining most suitable research methods.
May configure, operate, and/or maintain specialized equipment.
Identify methodological problems in research protocol and assist in implementing modifications to optimize experimental results.
Coordinate specialized and novel research functions.
May use software applications to assemble, manipulate, format and/or perform statistical analyses of data.
Prepare and present written or oral progress reports concerning studies, including assembly, organizational and interpretation of data.
Present data to the Principal Investigator (monthly progress reports), to the entire lab (lab meetings ~1-2 times a year), and occasionally at scientific meetings.
Train others in complex technical protocols.
Shares significant responsibility for results of research project or project team. Manages own research project with input of the Investigator. Intermediate to long term impact on results of entire lab.
Successful candidate has the chance to work in the exciting and rapidly expanding field of planarian regeneration with a diverse group of talented and dedicated scientists.
Play a vital collaborative role in the Newmark lab and actively contribute to research efforts of other lab members.
Establishes intermediate range goals and schedules work to meet those goals. Work is reviewed at key stages by supervisor but individual is largely self-directed. May monitor performance of others and provide or propose required training. May develop, or lead the development of, training tools. May plan for and provide working supervision to a group of laboratory employees of lower grade engaged in the performance of technical and professional work and a variety of complex to routine to complex tasks.

Required Experience
Ph.D. (currently or by May 2017) with experience in molecular biology.
Expertise in generating transgenic lines, preferably at the organismal level.
Knowledge of or experience with current CRISPR/Cas9 technologies.
Experience with viewing and analyzing genomic/transcriptomic sequence data.
Excellent oral communication and interpersonal skills.

Please include the answers to the following questions in your cover letter:
Do you have any experience with transgenic technologies?
In what experimental system?
How familiar are you with CRISPR/Cas9?
Job Location
Madison, Wisconsin, United States
Position Type
Full-Time/Regular


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NMR Research Specialist

Date Posted:
3/17/2017

HHMI

MA

The Howard Hughes Medical Institute currently has an opening for a PhD-level NMR scientist to join Dr. Dorothee Kern’s laboratory as a Research Specialist. This unique position, in the Department of Biochemistry at Brandeis University (located 10 miles west of Boston MA), is suitable as a partnership with Dr. Kern. It offers the opportunity to collaborate with a variety of cutting-edge scientists within the Brandeis University community.

Dr. Dorothee Kern uses biophysical analytical techniques to unravel the dynamic personality of enzymes, signaling proteins, and the molecules they affect. The NMR Research Specialist will be responsible for overseeing NMR spectroscopic activities including training of graduate students and postdocs. You will also be responsible for implementing and optimizing new pulse programs.

The laboratory is equipped with Inova Varian 600, 500 and 400 MHz NMR spectrometers, and a Bruker Advance II 800 MHz spectrometer with cryoprobe. 900 MHz spectrometers are available in Boston and at UC Boulder. Brandeis University provides significant personnel support for hardware management and maintenance that will allow you to focus on advanced scientific studies.

The Research Specialist position provides PhD-level scientists the opportunity to work in a stimulating academic research environment and to continue their scientific development. You will collaborate on exciting ongoing work with lab members and have the opportunity to establish an independent research project.

To apply for this position, click on the link below. Please submit a cover letter, attn: Charlene Tribbett-Talley, that includes three references, along with your resume/CV.
Required Skills
Partner with PI to help achieve long-term goals for the laboratory by working with lab members and collaborators.
Day-to-day interactions with graduate students and post-docs to provide guidance and refine NMR techniques.
Develop and provide NMR training to lab personnel as needed.
Monitor progress of projects and suggest improvements.
Keep up-to-date on advances in the field by reading the literature and attending meetings.
Use up-to-date knowledge to evaluate approaches and technologies and make recommendations for improvements to achieve research goals.
Work with the PI to review operational needs of NMR activities, and develop and implement intermediate and long-term goals.
Conduct experiments tailored to the goals of the lab and the experience of the candidate.
Required Experience
Ph.D. in Biochemistry, Physics, Biosphysics or Chemistry with postdoctoral experience preferred.
Proven track record in high-resolution biomolecular or solid-state NMR.
Highly advanced knowledge in NMR spectroscopy
Strong verbal and written communication skills.
Excellent interpersonal skills.
Ability to develop innovative processes to achieve goals.
Must be a dedicated and independent thinker with strong research and organizational skills.
This position will require a driven, creative individual who is willing to tackle novel challenges and continually work towards process improvement.


HHMI is an Equal Opportunity Employer
Job Location
Waltham, Massachusetts, United States


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Postdoc molecular biology

Date Posted:
3/17/2017

HHMI

WI

At the Howard Hughes Medical Institute (HHMI), creativity and excellence are fundamental to our success. As one of the world's largest philanthropies, HHMI is a major force in advancing biomedical research and science education.

The Ahlquist laboratory at the University of Wisconsin-Madison is recruiting a post-doctoral researcher to study the molecular mechanisms of viral and host interactions in positive-strand RNA virus genome replication. Projects include multiple aspects of the structure, assembly and function of viral RNA replication complexes, which are fascinating molecular machines and major targets for virus control. These highly synergistic studies integrate cutting-edge molecular genetics, biochemistry, cell biology, and cryo-electron microscopy with bioinformatics and computational biology.

Successful candidates will join a dynamic, multidisciplinary team with diverse backgrounds and expertise in a well-equipped, interactive research environment on the campus of the UW-Madison. We offer an extraordinary work environment built around a multi-disciplinary fusion of ideas, state-of-the-art facilities, and commitment to mentorship. UW-Madison consistently ranks among the top U.S. universities for research and development and the City of Madison among the 'best places to live in the US' with a diversity of outdoor and cultural opportunities.


Additional Information

For more information, please see:
http://www.hhmi.org/scientists/paul-ahlquist
http://mcardle.wisc.edu/bio/ahlquist_p.html


To Apply

Qualified candidates interested in this opportunity are required to submit a single pdf document containing their CV and a cover letter detailing their current/previous research and names/address of three references as one document to

Johan den Boon
Associate Scientist
email: JdenBoon@morgridge.org



HHMI is an Equal Opportunity Employer


Required Skills
Candidates should have a Ph.D. in cell and molecular biology, genetics, biochemistry, microbiology, or a related field, and proven research productivity as demonstrated by publications. The ideal candidate will be a highly motivated, creative person with the ability to learn quickly and function both independently and within a team, and with excellent written and oral communication skills.

Job Location
Madison, Wisconsin, United States


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Postdoc HIV

Date Posted:
3/17/2017

HHMI

NY

Job Description
The laboratory of Dr. William R. Jacobs, Jr. of the Howard Hughes Medical Institute at the Albert Einstein College of Medicine/Montefiore Medical Center is seeking a highly motivated and innovative post-doctoral scientist interested in the development of vaccines against Tuberculosis and HIV using a novel recombinant Herpes Simplex Virus-2 (HSV-2) ΔgD vaccine vector (Petro, C., Gonzalez, P. et al. 2015 eLife PMID 25756612; Petro et al. 2016 JCI Insight PMID 27536733). The project will involve mechanistic analyses with the aims of exploring the use of vaccine vectors that elicit high titer FcR activating ADCC antibodies to provide protection against HIV and Mycobacterium tuberculosis. This work will be conducted in collaboration with Dr. Betsy Herold, Pediatric Infectious Diseases and Microbiology-Immunology at Einstein/Montefiore.
Required Skills
Job Requirements:

Applicants must have a PhD, MD, or equivalent degree, with a track record of research excellence, and expertise in genetic manipulation of Herpes viruses or M. tuberculosis, immunological analyses or animal infection models. Qualified applicants should submit a cover letter, curriculum vitae, and a brief summary of research accomplishments and goals in a single PDF document to jacobsw@hhmi.org. Applicants should also arrange to have three letters of reference sent directly to this email address.

The Albert Einstein College of Medicine is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information. Einstein seeks candidates whose skills, and personal and professional experience, have prepared them to contribute to our commitment to diversity and excellence, and the communities we serve.


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Postdoctoral Fellow neuroscience electrophysiology

Date Posted:
3/17/2017

HHMI

WI

Howard Hughes Medical Institute (HHMI) is a science philanthropy whose mission is to advance biomedical research and science education for the benefit of humanity. We empower exceptional scientists and students to pursue fundamental questions about living systems, and work to share scientific discoveries with researchers, students, and science-curious individuals around the world.

Founded in 1953 by aviator and industrialist Howard R. Hughes, HHMI is headquartered in Chevy Chase, Maryland, and employs more than 2,500 people across the U.S. Visit hhmi.org/careers to learn more about working at HHMI.

The Chapman lab is looking for a highly motivated postdoctoral electrophysiologist to study aspects of neuroscience. Our lab is interested in Ca2+ regulated synaptic vesicle exocytosis, synaptic transmission and neuronal circuit activity. The successful candidate will conduct patch clamp experiments using cultured neurons and brain slices to measure synaptic depression, paired pulse facilitation, and other aspects of synaptic plasticity. Other goals are to: understand how the interplay between various organelles influences synaptic function, assign functions to synaptic vesicle and presynaptic proteins, probe the structure and function of fusion pores, and understand the factors that control oscillations in neuronal circuits. This postdoc researcher is also expected to contribute ideas, interact and collaborate with other lab members and other laboratories, and to prepare manuscripts for publication.

How to Apply
Please send you letter of interest, CV and publication list.

HHMI is an Equal Opportunity Employer
Required Skills
Requirements
A Ph.D. or equivalent degree in neuroscience or related discipline is required. A strong background in electrophysiology is essential for this position. Experience conducting patch clamp recordings in cultured neurons and brain slices is highly preferred.

Besides electrophysiology, the ideal candidate would also be familiar with imaging (of Ca2+, pHluorin, etc.) or optogenetics, and other regular lab skills in a biomedical research group.

Analysis of electrophysiology and image data.

Self-motivated, able to work independently and as part of a team.

Strong verbal and written communication skills.

Job Location
Madison, Wisconsin, United States
Position Type
Full-Time/Regular


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Postdoctoral Fellow Neurogenesis

Date Posted:
3/17/2017

HHMI

CA

At the Howard Hughes Medical Institute (HHMI), creativity and excellence are fundamental to our success. As one of the world's largest philanthropies, HHMI is a major force in advancing biomedical research and science education in the U.S. and beyond.

We have an exciting postdoctoral position available in the Chang lab at the University of California, Berkeley. The Chang lab studies the molecular roles of metals and redox-active small molecules relevant to human health, focusing on the physiology of brain, immune, and fat systems and how they are compromised in aging and disease.

Principal Responsibilities:

The ideal candidate will be responsible for studying the role of redox signaling in neurogenesis and neural plasticity.
For information on Prof. Chang’s lab click on the research abstract link above or visit: http://www.hhmi.org/research/metals-and-redox-biology

Preferred Qualifications:

Applicants must have a PhD in Molecular and Cell Biology, Neurosciences or other related fields with a strong academic record demonstrated by publications in peer-reviewed journals.
Experience in mammalian cell culture, primary cell and slice culture, RNAi, viral transfection, and confocal imaging is required.
Experience in mouse genetics, stereotactic surgery, brain slice preparation, electrophysiology, functional imaging, high-throughput screens, and super-resolution imaging is highly desirable.
Highly motivated individual that can work autonomously and with a team of scientists from diverse backgrounds.

Additional Information:
Interested candidates should send a single PDF with a cover letter, CV, and names of three references to Christopher Chang, PhD at chang.berkeley.hhmi@gmail.com. Please include the job title in the subject line.

To Apply

To apply for this position, please email your resume to:

Chris J. Chang, PhD
Investigator

E-mail: chang.berkeley.hhmi@gmail.com


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Postdoctoral Fellow Physiology Lipid Metabolism

Date Posted:
3/17/2017

HHMI

MA

At the Howard Hughes Medical Institute (HHMI), creativity and excellence are fundamental to our success. As one of the world’s largest philanthropies, HHMI is a major force in advancing biomedical research and science education.

We have a postdoctoral position available in the laboratory of HHMI Investigator, Tobias Walther, Ph.D., and Robert V. Farese, Jr, M.D., who jointly run a highly collaborative group at the Harvard School of Public Health. The lab is located in the Boston Longwood medical campus and is affiliated with the Department of Genetics and Complex Disease (HSPH), the Department of Cell Biology (Harvard Medical School), the Broad Institute of MIT and Harvard, and the Howard Hughes Medical Institute.

The Walther-Farese Laboratory studies the biochemistry of cellular lipid metabolism and membrane homeostasis. We seek outstanding candidates with Ph.D. training in physiology and in vivo models of lipid metabolism. Projects are available in the areas of fatty acid, cholesterol and sphingolipid homeostasis.

Applicants should possess a Ph.D. or M.D./Ph.D. in cell biology or neurodegenerative disease research and have an outstanding publication record.

For additional information, please visit our webpages:
https://faresewaltherlab.hms.harvard.edu
http://cellbio.med.harvard.edu/people/faculty/farese-jr
http://cellbio.med.harvard.edu/people/faculty/walther
https://www.hhmi.org/scientists/tobias-c-walther

To Apply
Interested candidates should send a cover letter, Curriculum Vitae and three letters of reference to: robert@hsph.harvard.edu and tholmes@hsph.harvard.edu. Please include the position title in the subject line.
Job Location
Boston, Massachusetts, United States
Position Type
Full-Time/Regular


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Postdoctoral Fellow Cellular Neurodegeneration

Date Posted:
3/17/2017

HHMI

MA

At the Howard Hughes Medical Institute (HHMI), creativity and excellence are fundamental to our success. As one of the world’s largest philanthropies, HHMI is a major force in advancing biomedical research and science education.

We have a postdoctoral position available in the laboratory of HHMI Investigator, Tobias Walther, Ph.D., and Robert V. Farese, Jr, M.D., who jointly run a highly collaborative group at the Harvard School of Public Health. The lab is located in the Boston Longwood medical campus and is affiliated with the Department of Genetics and Complex Disease (HSPH), the Department of Cell Biology (Harvard Medical School), the Broad Institute of MIT and Harvard, and the Howard Hughes Medical Institute.

The Walther-Farese Laboratory studies the biochemistry of cellular lipid metabolism and membrane homeostasis. We seek outstanding candidates with Ph.D. training in cellular and murine models of neurodegeneration. Projects are available in the areas of lyososome biology and frontotemporal dementia and in the area of altered sphingolipid homeostasis and neurodegenerative diseases.

Applicants should possess a Ph.D. or M.D./Ph.D. in cell biology or neurodegenerative disease research and have an outstanding publication record.

For additional information, please visit our webpages:
https://faresewaltherlab.hms.harvard.edu/
http://cellbio.med.harvard.edu/people/faculty/farese-jr
http://cellbio.med.harvard.edu/people/faculty/walther
https://www.hhmi.org/scientists/tobias-c-walther

To Apply
Interested candidates should send a cover letter, Curriculum Vitae and three letters of reference to: robert@hsph.harvard.edu and tholmes@hsph.harvard.edu. Please include the position title in the subject line.
Job Location
Boston, Massachusetts, United States
Position Type
Full-Time/Regular


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Human Subjects and Clinical Trials Specialist

Date Posted:
2/10/2017

NIH/Ripple Effect Communications

MD

Position Description:
The National Institutes of Health (NIH) is the nation's premier biomedical research agency. Within the Office of Extramural Research (OER), the Office of Extramural Programs (OEP) provides leadership for the management of trans-NIH programs via the development of programs and policies, interpretation, coordination, oversight, evaluation, training and outreach for NIH extramural staff and the extramural research community. As such, OEP is tasked with helping to provide oversight and direction for the implementation of initiatives aimed at enhancing the stewardship, accountability, and transparency of clinical trials. Several recent initiatives, including the NIH policy on dissemination of clinical trials information, the single IRB policy, and the new 21st Century Cures bill will necessitate major changes for NIH. Ripple Effect is seeking a full-time staff member to work with OEP and other NIH components to implement initiatives to enhance the stewardship of clinical trials. This is a 1-year appointment with the possibility of an extension.

Background:
Ripple Effect attracts high-achievers who consistently attain above-average results and take responsibility for solving problems. Our clients engage us because we bring intelligence, innovation, initiative, and impact to project management. We need self-starters who get the job done, who can handle a wide range of support tasks, and who enjoy the energy of a government office with intelligent colleagues and fast-paced programs.

Job Description:
Apply if you're looking for a job that delivers these opportunities:

  • Contribute to high-level functioning within a government agency
  • Interact professionally with government clients
  • Think on your feet while mastering new tasks quickly and independently

Preference will be given to individuals who are performing at this level successfully. Job offer is contingent upon task order award.
The Program Manager will provide program administration and subject-matter expertise by completing the following tasks:
Task 1: Provide subject matter expertise

  • Advise OER on optimal approaches to implementation of clinical trials and privacy related policies and regulations.
  • Provide technical expertise in the development of new or revised products (policies, guidance, instructions, procedures resources, etc) needed for oversight of the NIH clinical trials policies and procedures
  • Provide technical expertise in the development of new or revised products (draft regulations, policies, guidance, instructions, procedures resources, etc) for NIH privacy protections programs and/or certificates of confidentiality
  • Use expertise to assess products proposed by others in OER, NIH, and the extramural research community
  • Prepare reports that reflect current state-of-the-art on topics in areas of expertise to help guide OER decisions

Task 2: Program Management

  • Use the appropriate project management processes, skills, and resources to oversee projects pertaining to clinical trials and privacy.
  • Employ techniques to define, plan, organize, schedule, budget, manage and close out projects
  • Oversee and manage project teams (e.g., coordinate subgroups to ensure tasks are ongoing and completed on time)
  • Formulate, organize and monitor inter-connected projects
  • Resolve higher scope issues
  • Manage stakeholder expectations
  • Prepare supporting documents for clearance requests

Task 3: Program Support

  • Represent OEP positions at meetings within and external to NIH.
  • Provide program support to OEP on related extramural initiatives

Qualifications:

  • Possess a Master's degree or higher from an accredited university
  • Have adept skills and knowledge of Microsoft Office tools (i.e., Word, Excel, PowerPoint, SharePoint)
  • Have a working knowledge of program/project management software (e.g., MS SharePoint, Basecamp, MS Project etc.)
  • Possess excellent problem-solving and communication skills
  • Have experience in project or program management
  • Have knowledge and understanding of the management and conduct of clinical trials (preferably NIH clinical trials), including knowledge of privacy protection regulations and certificates of confidentiality
  • Have a scientific background acquired via education, training and/or experience
  • Experience with NIH preferred, particularly the extramural research programs
  • Be willing and able to work full time on the client site during core business hours

To Apply:
Please apply to this position directly on the Ripple Effect website. In case needed, here is the direct link for the application:https://ripple-effect-communications-inc.workable.com/jobs/416594


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Laboratory Manager

Date Posted:
3/17/2017

HHMI

TX

To manage a large, high-paced laboratory and to participate in conducting research on stem cells from the nervous and hematopoietic systems. Qualified applicant will be expected to provide advice, assistance, and supervision to graduate students and postdoctoral fellows in the laboratory. In addition, this individual would also be responsible for the overall management of the laboratory, in conjunction with the principal investigator, and other technical and administrative support staff.

The successful candidate would provide senior-level technical lab support and act as a specialist on laboratory methods and equipment functions. The successful candidate would be able to instruct lab members in techniques, instrument utilization, methods, and procedures as well as interact with university regulatory staff to ensure the laboratory meets all regulatory standards.

MINIMUM QUALIFICATIONS:
Masters or Ph.D. degree in biological/biomedical science and 5-6 years of experience in some area of biomedical research. Previous research experience is required.

DESIRED QUALIFICATIONS:
Experience in laboratory management in the fields of molecular, cellular, and/or developmental biology.


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Postdoctoral Fellow Computational Biology

Date Posted:
3/17/2017

Jackson Labs

CT

About JAX-GM: Comprising 183,000 square feet of highly advanced, state-of-the-art laboratories and supporting facilities, the brand new JAX-GM conveniently sits midway between NYC and Boston in the heart of Connecticut. JAX-GM is part of an exciting $1.1 billion venture between the state of Connecticut and The Jackson Laboratory, an internationally-recognized research and educational institution with unparalleled genomic resources and research support services.
About the position: A postdoctoral research position in computational biology is available in Principal Investigator Sheng Li’s lab at the Jackson Laboratory for Genomic Medicine. The goal of the Li Lab is to contribute to the development of novel therapies that address cancer evolution. Our research focuses primarily on (1) understanding the epigenome dynamics during cancer evolution over time and under therapy; and (2) the mechanisms and translational implications of cancer cells population heterogeneity and plasticity.
We are looking for applicants who are excited to work in the creative and dynamic environment ingrained in JAX’s collegial, collaborative, interdisciplinary, and diverse research culture.
Key Responsibilities
The postdoctoral researcher is expected to develop new analytical methods for cancer epigenome/transcriptome data integration, and to analyze bulk and single-cell sequencing data sets from clinical studies.
Minimum Qualifications
PhD in a statistics, biostatistics, computer science, physics, computational biology, bioinformatics, or a related field with knowledge of statistics
A strong computational background (proficiency in at least one programming language required)
Excellent communication skills and fully fluent spoken and written English
A passion for solving cutting edge research problems of computational biology
The Following Optional Qualifications Are Considered Advantageous
Knowledge of (and/or work experience with) machine learning methods
Experience with large-scale data analysis using software pipelines in an HPC environment
Experience in software development
Research experience in next-generation sequencing data analysis and utilization of public available bioinformatics resources
More About Jax
JAX began in 1929 with a small group of scientists dedicated to the emerging field of genetics. We now have over 1700 scientists, technicians, and support staff, including over 50 Principle Investigators in five primary disease areas: cancer, reproductive biology, immunology, metabolic processes, and neuroscience. Our fundamental contributions to biomedical research include cancer genetics and establishing the mouse as the premier research animal model.
Uncover more of our historic milestones, including the 26 Nobel prizes associated with our research, resources, & education
Read our latest news & insights for a glimpse at how we’re impacting the future of biomedicine
Follow the progress we’re making on our quest to improve human health via our recent research highlights


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Research Fellow Psychiatric Diseases

Date Posted:
3/17/2017

Partners Health Care

MA

McLean Hospital is a comprehensive psychiatric hospital committed to providing easy access to superior quality, cost-effective mental health services in the Boston area, Massachusetts and beyond. Since 1811, McLean Hospital has been a world leader in the treatment of mental illness and chemical dependency, research into the cause of mental illness and the training of generations of mental health care providers. McLean's multidisciplinary programs treat a broad range of psychiatric illnesses across the full continuum of care.
General Summary
Psychosis Neurobiology Laboratory, Psychotic Disorders Division (McLean Hospital and Harvard Medical School) is seeking a research scientist to perform neurophysiological and computational modeling analyses of psychiatric diseases – acquiring and analyzing an array of biological and behavioral data to better understand the mechanisms and recovery trajectories for severe mental illness, particularly bipolar disorder and schizophrenia.
Data obtained in the lab include (1) an array of EEG and event-related potential responses (2) GWAS genotype, (3) structural brain imaging and brain biochemistry, (4) cognition, (5) functional recovery assessments, and (6) an array of clinical assessments. This position requires maintaining and extending data processing pipelines of longitudinal studies and applying explanatory computational models (data-driven) to test underlying brain and behavioral mechanisms and to develop optimize predictive models of outcome trajectories.
The candidate should have a background in neuropsychiatry, neuroscience, bioinformatics, biostatistics, computer and information science, or a related discipline (including data mining) with primary experience in apply/develop computational approaches for integrating/linking large datasets in psychiatry or neuroscience. Programming skills in Matlab, R, and Unix/Linux and scientific computing are highly desired. Secondary experience with image processing would be helpful.
The candidate will be based in the Psychosis Neurobiology Laboratory and Psychotic Disorders Division and will participate in studies with humans. In addition to the primary projects, research collaborations can be undertaken with interdisciplinary investigators in cognitive science, clinical service, and anxiety and depression among others. The selected candidate will also be encouraged to develop his/her own independent research projects.
Salary is commensurate with experience and excellent benefits are included. McLean is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment.
All McLean team members are expected to consistently demonstrate our values of integrity, compassion, respect, diversity, teamwork, excellence and innovation in their work activities and interactions.
Primary Location
MA-Belmont-McLean Hospital Main Campus
Work Locations
McLean Hospital Main Campus
Job
MD/PHD/Fellows/ PostDocs
Organization
McLean Hospital(MCL)
Schedule
Full-time
Standard Hours
40
Shift
Day Job
Employee Status
Regular
Recruiting Department
MCL Research
Job Posting
Mar 15, 2017
Required
PhD or MD in neuroscience, psychiatry, computer and information science, bioinformatics, statistics or related fields.
Candidates should have previously participated in research or performed relevant coursework in neurophysiology, psychiatric neurobiology, statistical or computational analyses.
Experience with EEG and/or neuroimaging data processing.
Preferred
Master degree or equivalent level education in biostatistics, bioinformatics, computer science, data science or other discipline requiring intense data analysis
1-3 years of experience in computational approaches for integrating across multiple data types to identify risk patterns and to develop predictive models.
Technology Statement
All employees must possess basic computer skills to use a variety of electronic or online systems for communication, clinical and administrative purposes.


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Research Scientist

Date Posted:
3/17/2017

Synaptics

CA

Synaptics is the pioneer and leader of the human interface revolution, bringing innovative and intuitive user experiences to intelligent devices. Synaptics’ broad portfolio of touch, display, and biometrics products is built on the company’s rich R&D and supply chain capabilities. With solutions designed for mobile, PC and automotive industries, Synaptics combines ease of use, functionality and aesthetics to enable products that help make our digital lives more productive, secure and enjoyable. (NASDAQ: SYNA)
Job Responsibilities
The R&D group at Synaptics is searching for a Biometrics scientist to develop technologies for next-generation biometric sensors and human / computer interfaces. This position reports to the Director of Advanced Development in the R&D group.
Independently execute on a research program in biometric sensors or human / computer interfaces
Communicate research progress and results
Transfer technology from research to development teams
Evaluate potential impact of different technologies on company’s core businesses
Required Qualifications
Master's degree in Engineering/Science; PhD preferred
10+ years of research experience with a demonstrated ability to create innovative technology and transfer from research to engineering development
Broad technical experience is essential. Skills in some or all of the following areas are necessary:
Human computer interfaces
Sensors
Optics
Image processing
Electrical engineering & signal processing
Systems engineering
Materials science
Physics
Mathematics
Excellent communication skills
Track record of publications / patents and presentations


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Medical Writer - Respiratory

Date Posted:
3/17/2017

health Interactions

NJ

Health Interactions is an international medical education agency providing innovative, high-quality and effective healthcare communications. As we are part of Nucleus Global, our clients benefit from the synergies available within our global network of offices staffed by highly talented individuals who can deliver on a global scale or a local level and across a broad spectrum of therapy areas.

Our success has led to continued expansion both in the range of services we offer and our global presence. We are now looking for a talented and enthusiastic Medical Writer.

This is your chance to work as part of a highly scientific team. This varied role involves writing accurate scientific / commercial copy for a range of printed and computer-based scientific materials from technical manuscripts to congress materials, interactive web projects and sales aids.

Working with leading international pharmaceutical clients, you will have the opportunity to interact with some of the world’s leading scientists and physicians on critical therapeutic and scientific issues. You will be required to participate in client meetings / teleconferences and attend scientific meetings such as congress, symposia and advisory boards and participate in pre-meetings, onsite activities and post meeting work as required / appropriate.

You should be passionate about communicating science to a variety of audiences and be able to add a creative edge and maintain quality standards. You will be interacting with some of the world’s leading scientists and physicians on critical therapeutic and scientific issues to make cutting-edge science accessible to those who need it.

To succeed you will have an advanced degree in the life sciences (PhD, MD or PharmD is mandatory). Previous relevant medical information, communications or marketing writing experience (agency or pharmaceutical) with specific expertise in respiratory is highly preferred. We also welcome candidates out of an academic environment with relevant research experience.


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Postdoc

Date Posted:
3/17/2017

Broad Institute

MA

Dr. Sekar Kathiresan's laboratory at the Broad Institute of MIT and Harvard seeks to hire a highly motivated postdoctoral fellow. The Kathiresan Lab is focused on understanding the genetic basis of coronary heart disease and its related quantitative phenotypes. The successful applicant will work on applying computational methods and performing large scale data analyses to identify novel common and rare variants which influence risk of cardiovascular and other cardiometabolic disease. In addition, they will use known genetic variants linked to these diseases and examine whether novel biomarkers and pathways casually influence risk.
PhD in Computer Science, Engineering, Math, Statistics, or a related quantitative discipline
EOE / Minorities / Females / Protected Veterans / Disabilities
Equal Opportunity Employer Minorities/Women/Protected Veterans/Disabled


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Neuroscientist

Date Posted:
3/17/2017

Regeneron

NY

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including oncology, rheumatoid arthritis, asthma, atopic dermatitis, pain, and infectious diseases.
Summary
We are seeking a talented scientist to join our Neuroscience research group. This individual should have an extensive background in mechanisms of neuronal pathology and neurodegeneration. Candidates with experience in neurotrophin biology are particularly encourage to apply. The successful candidate will be responsible for hands-on research studies designed to investigate novel targets and neuroprotection strategies for demyelinating disorders, motor neuron diseases, and peripheral neuropathies. The ideal candidate will be a motivated, self-starter and will have the opportunity to be a key part of an exciting new research focus.
Responsibilities
This candidate will work within a multidisciplinary group to design and execute a broad range of neuroscience experiments using both cell-based approaches and animal models. This candidate should have expertise with basic cell culture and molecular biology techniques (cloning, plasmid generation, etc.). The candidate should be flexible and open to learning cutting edge new techniques as needed. Also, this candidate should demonstrate the ability to teach and guide others using their areas of expertise. The candidate will be responsible for the reporting of results to a broad range of audiences and a high level of presentation and communication skills are required.
Requirements
This position requires a PhD with completion of a post-doctoral fellowship in a nationally recognized laboratory, 3+ years of post-PhD research experience. Required experience includes:?- Cell biology techniques.?- neuron biology (in the context of multiple sclerosis or other demyelinating diseases/neuropathy) or motor neuron disease (ALS).?- Must have working knowledge of experimental design and statistical analysis.??Level will be commensurate with experience
This position will require the individual to pass a physical before beginning employment.
This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron’s unwavering commitment to combining good science & good business.
To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid.
Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.


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Scientist Immunoassay development

Date Posted:
3/17/2017

Regeneron

NY

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including oncology, rheumatoid arthritis, asthma, atopic dermatitis, pain, and infectious diseases.
Summary
We are looking for a scientist with experience in immunoassay development and validation to work in the Assay Development group at Regeneron. The scientist will develop, validate and perform biomarker, PK and immunogenicity assays for biotherapeutics to support preclinical and clinical studies. The individual should have the ability to exercise independent judgment regarding interpretation and optimization data.
Responsibilities
Design, develop and validate immunoassays using ELISA, MSD or Gyros platforms for pharmacokinetic (PK), anti-drug antibodies (ADA) or biomarker detection in serum or plasma to support clinical or non-clinial bioanalysis
Analyze and summarize data
Troubleshoot assay problems
Reads and critically evaluates the literature in the bioanalytical field in order to develop novel approaches to develop and perform assays
Communicates effectively with supervisor and other managers within the Assay Development Group
Write development and validation reports and SOPs
Requirements
PhD in Biology, Immunology or a related field
1 year of biotech/pharma/CRO experience with biotherapeutics preferred
Experience in the development/validation of ELISAs and/or MSD assays for protein biopharmaceuticals in a regulated environment under GLPs
Experience with other assay platforms is a plus
Excellent organizational and communication skills, ability to multitask
Ability to maintain detailed lab notebook and keep a safe lab environment
Ability to effectively interact with colleagues in a team environment
Ability to independently plan, supervise and direct projects to completion, within required timelines, are essential
Supervisory experience is a plus


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Technical Writer/Editor II

Date Posted:
3/17/2017

BioRad

CA

Serve as editor and writer for the Life Science Group's Global Marketing and Communications Department
Partner with Marketing, Campaign, and Product Managers to develop concepts and content for advertising and marketing campaigns
Develop, write, and edit content marketing articles such as trends articles, customer stories, and content for bioradiations.com
Develop, write, and edit marketing materials such as brochures, fliers, technical/application notes, posters, video scripts
Ensure marketing and advertising collateral meet editorial style guidelines and are scientifically accurate
Collaborate in project teams with Art Directors, Graphic Designers, and Project Managers
What You Need For This Role
Master's degree in the life sciences (a must) and at least 3 years of experience writing and/or editing for a scientific audience or a PhD in the life sciences
Scientific knowledge -- Understands basic scientific concepts and laboratory techniques in molecular biology and biochemistry (chromatography, western blotting, etc.); communicates using accurate scientific language; understands what motivates researchers in the life sciences and how to write copy that resonates with them
Scientific writing/editing -- Is familiar with the structure and style of scientific articles; has written or contributed significantly to the writing of scientific articles; can provide feedback on logical progression of scientific ideas/arguements
Writing Skills -- Has strong writing skills and the ability to write a variety of materials (technical/application notes, advertising copy, brochure/flier copy, customer stories and trends articles, video scripts); must be able to adapt voice to match intent/purpose of each piece
Editorial Skills -- Has strong attention to detail and is familiar with Chicago Manual of Style or AMA Manual; is able to ensure internal consistency when editing lengthy documents; is able to consistently enforce style guidelines across all documents
Organizational Skills -- Is able to manage multiple projects simultaneously and effectively under tight deadlines
Must be able to uphold editorial style guidelines and provide guidance on writing style and strategy in a professional manner
Enjoys and is able to work effectively in a changing team environment
Candidates will be asked to take a writing and editing test for this position
What’s In It For You
Competitive pay and great benefits including medical, dental, vision, 401k and more
Opportunities for growth and training
Stability of a profitable 60+ year old company
Great work environment
About Bio-Rad
Bio-Rad is a global leader providing a broad array of clinical diagnostics and life science research products. With a team of more than 7,800 employees and a global network of operations serving our customers, we help people live longer, healthier lives.
Bio-Rad was founded over six decades ago and has continued to provide the healthcare industry with innovative and useful products that help life science researchers accelerate the discovery process and medical diagnostic labs obtain faster, better results.
EEO/AA Employer/Veterans/Disabled/Race/Ethnicity/Gender/Age
To all recruitment agencies: Bio-Rad does not accept agency resumes, unless the agency has been authorized by a Bio-Rad Staffing Representative. Please do not submit resumes unless authorized to do so. Bio-Rad will not pay for any fees related to unsolicited resumes.


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Bioinformatics Data Scientist

Date Posted:
3/17/2017

CyberCoders

PA

If you are a Bioinformatics Data Scientist with experience, please read on!
Located in the heart of Philadelphia, We are a well-funded, clinical stage, computational bio-sciences company with a focus on patient risk and cardiovascular monitoring. We are as passionate as ever about developing new technologies to detect and identify cardiovascular health as well as potential risk factors. We are seeking a seasoned Bioinformatics Data Scientist to join our computational research team!
What's In It for You
Hot Growth Startup Environment (Well-funded)
Leading technologies
Great Team and Notable Leadership
Vacation/PTO
Generous Benefits Package
What You Will Be Doing
Develop, deploy, and analyze database-driven computational analysis systems that carry out high-dimential data analysis and data mining solutions.
Develop and apply state-of-the-art computational analysis and interpretation approaches to leverage internal, public and partner datasets and empower data-driven program decision-making
Develop collaborations with external partners (Universities, Industry, other National Laboratories) to advance computational biology simulation efforts.
Integrate data across multiple experimental platforms and transfer knowledge from pre-clinical experiments to clinical trials.
Define and articulate best practices in software version control, test-development, and deployment
What You Need for this Position
At Least 4 Years Of Experience And Knowledge Of
A Master's Degree or PhD in Computer Science, Bioinformatics, Computational Biology or a related field preferred.
Expert knowledge in R, Python or shell scripting and is familiar with UNIX environments.
Excellence in Data mining and empirical modeling (Machine Learninga big plus)
Programming (R, Matlab, Python, Java)
Web application deployment (Apache, php, tomcat, Ruby/Rails, Grails)
Database technology (MySQL)
R/Bioconductor experience
Experience in Bioinformatics or Computational Biology (highly preferred)
So, if you are a Bioinformatics Data Scientist with experience, please apply today!
Email Your Resume In Word To
Looking forward to receiving your resume through our website and going over the position with you. Clicking apply is the best way to apply, but you may also:
Sam.Lee@CyberCoders.com
Please do NOT change the email subject line in any way. You must keep the JobID: linkedin : SL6-1341682 -- in the email subject line for your application to be considered.***
Sam Lee - Executive Recruiter - CyberCoders
Applicants must be authorized to work in the U.S.
CyberCoders, Inc is proud to be an Equal Opportunity Employer
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, protected veteran status, or any other characteristic protected by law.
Your Right to Work - In compliance with federal law, all persons hired will be required to verify identity and eligibility to work in the United States and to complete the required employment eligibility verification document form upon hire.
CyberCoders will consider for Employment in the City of Los Angeles qualified Applicants with Criminal Histories in a manner consistent with the requirements of the Los Angeles Fair Chance Initiative for Hiring (Ban the Box) Ordinance.


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Scientific Manager - Immunology

Date Posted:
3/17/2017

MD Anderson Cancer Center

TX

The goal of MDA department of Immunology is to perform multidisciplinary research and educational activities in basic and cancer immunology.

The salary range is min $ 82,500 mid $ 123,600 max $ 164,800.

1. Key Functions:

* Contributes to the overall management of the Immunotherapy Platform across MD Anderson Departments and multi-institutional consortium networks. Establishes, develops, and fosters collaborative relationships with industry and academic leaders to assure advancement of organizational and platform goals. Ensures systems, policies and procedures are in place to facilitate successful collaborations.

* Ensures that strategic and tactical plans for the ongoing activities of the platform are developed and executed efficiently. Provides scientific input for all aspects of the platform including protocol management, budgets, contracts, and specimen procurement.
* Reviews, evaluates, interprets, and integrates medical records, patient data, patient specimens, and/or test results and provides correlation with the different laboratory analyses, including but not limited to flow cytometry, molecular pathology, Nanostring technology, murine/pre-clinical studies, etc..
* Exhibits understanding of the processes of clinical research and pharmaceutical product development/approval.
* Attends and may lead the face-to-face and/or teleconference IMT meetings with alliance partners and academic collaborators: able to give data presentations and facilitate discussions regarding the advancement of science and research.
* Assigns/manages tasks to ensure platform deadlines and milestones are met. Develops reports, Gantt charts, and other tracking tools to ensure ongoing updates are available to Immunotherapy Platform staff.
* Works closely with the department administrator, faculty, research management team, and informatics staff to address issues and coordinate the development and implementation of operational solutions related to research protocols and electronic research applications.
* Writes and prepares various reports. May assist in the writing and planning of research grants.
* Other duties as assigned.

EDUCATION:

Required: Bachelor's degree in one of the basic sciences.
Preferred: PhD in one the basic sciences.

EXPERIENCE:

Required: Seven years relevant research experience to include two years in a supervisory/managerial capacity. With preferred Masters degree, five years of required experience to include two years in a supervisory/managerial capacity and with preferred PhD, three years of required experience to include two years in a supervisory/managerial capacity.


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Scientist I

Date Posted:
3/17/2017

Bristol Meyers Squibb

NJ

In the Molecular and Analytical Development group of BMS, we are a world-class Mass Spectrometry and Biophysics Center of Excellence to support the development of life-saving medicines in immuno-oncology and other therapeutic areas. We specialize in biologics development using state of the art biophysical methods to decipher the structural complexities of biological molecules. We foster an innovative and collaborative environment that values and recognizes diversity of contributions, and pushing the limits of technology for analyzing monoclonal antibodies, fusion proteins, and other novel scaffolds progressing in clinical trials for unmet medical needs.
The Molecular and Analytical Development group is seeking a highly motivated and creative Biophysical Scientist to analyze structure, stability, and post-translational modifications of proteins to support development of biopharmaceuticals, and be part of the leadership position of BMS in Immuno-Oncology. This individual is also expected to push the limits of advanced biophysical techniques for characterization of therapeutic monoclonal antibodies, antibody drug conjugates, fusion proteins, and other protein modalities.
These Techniques Include, But Are Not Limited To
spectroscopy (FTIR, Raman, CD, fluorescence, UV/VIS)
analytical ultracentrifugation
microscopy (FTIR, Raman, AFM)
flow-based protein particulate enumeration and imaging (HIAC, MFI, FlowCam)
static and dynamic light scattering
calorimetry (DSC, ITC)
chromatography (SEC, IEX, RP)
capillary electrophoresis (iCIEF, SDS-CGE)
Additional responsibilities include defining critical quality attributes and understanding protein post-translational modifications including degradation pathways in in-vitro systems. He/she is also expected to publish novel findings in journals and present scientific data at internal and external conferences.
Responsibilities will also include matrix team leadership. The individual will work independently and in collaboration with colleagues within analytical and across various functional areas to support programs from clinical development through registrational studies.
An ideal candidate would have experience with therapeutic proteins including mAb, bispecific antibodies, fusion proteins, antibody drug conjugates and other derivatized proteins, and their structure-function relationships. Proven track record of independent research capability and problem solving ability is required for this position.
This individual will be required to interpret and present scientific data, contribute to IND, IMPD, BLA, and other regulatory filings, write technical reports and represent the department in matrix team environment when needed. Attention to detail and be able to work in a highly collaborative environment under tight timelines are required attributes.
We look for scientists who are truly inspired by our mission and who would share our passion for collaborative and entrepreneurial work culture. Because we know that employees are key to our success in bringing novel cancer medicines to patients, we are committed to providing employees with benefits that allow them to bring their best.
Bristol-Myers Squibb is an equal opportunity employer - Vet/Disability
Job Function
Analytical Chem - Mfg Ops
Primary Location
NA-US-NJ-Pennington
Organization
GMS - BDO
A PhD in biophysics, biochemistry, physical chemistry, chemical engineering, pharmaceutical science or a related scientific discipline with 0-3 years of relevant experience in biopharmaceutical/biotechnology, or a Masters with a minimum of 5 years of relevant experience is required.
Knowledge of protein chemistry, structure, function, and folding are essential.
The individual should possess demonstrated skills and proficiency in biophysical techniques including operation, maintenance and troubleshooting of instruments.
Familiarity with protein higher order structure analysis, protein particulate techniques such as flow imaging as well as microscopy is a plus.
The individual will interface and collaborate with multi-disciplinary teams in a high paced analytical laboratory environment.
Excellent communication, interpersonal and organizational skills are essential.
Attention to detail and be able to work in a highly collaborative environment under tight timelines is required.
Seniority Level
Not Applicable

Industry
Biotechnology Logistics and Supply Chain Pharmaceuticals
Employment Type
Full-time

Job Functions
Research Analyst Information Technology


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Chief Scientist Lab Diagnostics and Monitoring HIV

Date Posted:
3/15/2017

General Dynamics Land System USAMRIID

MD

This Chief Scientist position is in support of the Department of Laboratory Diagnostics and Monitoring, Military HIV Research program and requires a senior Doctoral level Scientist to provide scientific leadership, and management skills in the provision of the following services: Leadership of research activities in the HIV Lab Diagnostics and Monitoring Program to include development of assays and validation and adaptation of commercial assays for prevalent and emerging infectious disease pathogens. Oversight of the design, development and validation of reagants, test kits, platforms and laboratory developed tests for use in prevalent and emerging infectious pathogen screening, confirmation, and monitoring. Authorship of specialized scientific and technical reports Design and prepare research protocols in accordance with relevant regulatory, laboratory and ethical policies Preparation of presentations for national and international scientific forums

 

EducationDoctoral degree (PhD, ScD) in relevant scientific discipline.Qualifications10-15 years of related experience in scientific research, specifically in diagnostics, antivirals, and/or vaccines Demonstrated knowledge and experience with cooperative research and development agreements (CRADAs) and material transfer agreements (MTAs) Significant record of publication in peer reviewed literature

 

As a trusted systems integrator for more than 50 years, General Dynamics Information Technology provides information technology (IT), systems engineering, professional services and simulation and training to customers in the defense, federal civilian government, health, homeland security, intelligence, state and local government and commercial sectors.With approximately 32,000 professionals worldwide, the company delivers IT enterprise solutions, manages large-scale, mission-critical IT programs and provides mission support services.GDIT is an Equal Opportunity/Affirmative Action Employer - Minorities/Females/Protected Veterans/Individuals with Disabilities.

Seniority Level

Director

Industry

  • Defense & Space

Employment Type

Full-time

Job Functions

  • Engineering
  • Information Technology
 

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Sceintist I

Date Posted:
3/15/2017

Leidos

MD

The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish National Cancer Institute (NCI) research objectives. The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community. A major focus of the CRTP is the NCI RAS Initiative with the goal to discover new therapeutic interventions against RAS-driven cancers.

 

Responsibilities

 

JOB DESCRIPTION/BASIC FUNCTION

 

  • Will work in support of the FNL/NCI RAS Initiative with a highly collaborative multidisciplinary team of chemists, biochemists, structural and cell biologists, to develop and optimize agents for use as RAS inhibitors
  • Analyze high-throughput screening data to identify preliminary structure-activity relationships (SAR)
  • Provide synthetic support during hit validation studies
  • Conduct hit-to-lead chemistry efforts around those targets/screens that yield advanceable hits

     

Basic Qualifications

 

Qualifications:

 

To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:

 

  • PhD in a field related to medicinal chemistry, or in a related discipline from an accredited college or university according to the Council for Higher Education Accreditation (CHEA) appropriate to biomedical research, or eight (8) years of experience in lieu of degree
  • Foreign degrees must be evaluated for U.S. equivalency
  • Expertise in the design, synthesis, and characterization of pharmaceutically relevant small molecules
  • Experience with modern analytical technologies including: LCMS, NMR (1H, 13C, 2D techniques), HPLC, IR, Flash chromatography
  • Experience with the design and preparation of small-molecule compound libraries
  • Must be highly collaborative, self-motivated and team oriented
  • Must have excellent oral and written communication skills
  • Ability to efficiently manage workload over multiple projects
  • Must be able to obtain and maintain a Security Clearance

     

Preferred Qualifications

 

Candidates with these desired skills will be given preferential consideration:

 

  • Expertise in mass spectrometry (quantitative MS, MS/MS, MALDI-TOF, proteomics, and metabolomics)
  • Strong publication record

     

Leidos Overview

 

Leidos is a global science and technology solutions leader working to solve the world’s toughest challenges in the defense, intelligence, homeland security, civil, and health markets. The company’s 33,000 employees support vital missions for government and commercial customers. Headquartered in Reston, Virginia, Leidos reported pro forma annual revenues of approximately $10 billion for the fiscal year ended January 1, 2016 after giving effect to the recently completed combination of Leidos with Lockheed Martin's Information Systems & Global Solutions business (IS&GS). For more information, visit www.Leidos.com. The company’s diverse employees support vital missions for government and commercial customers. Qualified women, minorities, individuals with disabilities and protected veterans are encouraged to apply. Leidos is an Equal Opportunity Employer. Scientist / Research & Development


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Scientific Program Manager, Policy and Regulatory Lead Gene Drive Research

Date Posted:
3/15/2017

Foundation for NIH

MD

Position Description:
This is a professional scientific and administrative management position for an individual with experience and knowledge of international regulatory and policy issues relevant to biotechnology interventions aimed at improving public health. The Scientific Program Manager will participate in the strategic implementation of a portfolio of activities to support the successful introduction of gene drive technologies, with a focus on mosquitoes modified with driving transgenes as tools to control malaria transmission in Africa. The incumbent will provide administrative and regulatory advice and guidance to individuals and organizations (national and multi-national) with various different roles, responsibilities and interests in gene drive research and its potential deployment. This Scientific Program Manager will be responsible for regulatory and policy leadership within the team environment.

Essential Functions:

  • Facilitates the establishment and promotion of best practices for safe, ethical, and effective testing of a new and evolving technology. This includes, but is not limited to, planning and coordinating activities aimed at creating a uniform regulatory and policy environment for gene drive interventions aimed at malaria control, such as overseeing independent ecological risk assessments for interventions proposed for field testing, developing regulatory trainings, supporting regulatory-related capacity building for field testing at African sites and interacting with national and international policy-makers.
  • Collaborates with representatives of funding organizations, academic and other research organizations, regulatory, government and health-related agencies, and others to improve awareness and develop coordination of regulatory and related policy activities for gene drive technologies.
  • Interacts with individuals and organizations influential in decision-making on the introduction of new biotechnology products at the national and international level.
  • Provides technical and organizational leadership for regular convenings to initiate, improve and promote regulatory harmonization across sub-Saharan Africa.
  • Represents FNIH at relevant scientific, regulatory and policy meetings.
  • Assists, within a team environment, in designing new activities; creates timelines and resource plans; participates in relevant negotiations; and develops reports to funders and for distribution/publication.
  • Contributes to planning for and development of an anticipated, separately funded and sustainable new collaborative enterprise that will play a leadership role in long-term support for the development and implementation of gene drive approaches for malaria control.

The Scientific Program Manager will possess intellectual and scientific skills and knowledge as well as the organizational and administrative abilities to work effectively with a variety of internal and external partners. Recognizing the evolving approaches to and outcomes of research and regulations requirements, and ever-changing attitudes towards gene drive technology, s/he must be attentive to the rapid pace of technical advances, to proposed changes in policies and regulations and to community and public perception of the technology.
International travel to perform the functions of the Scientific Program Manager is estimated at 10-25% per year.
The incumbent will report to the Director of the Science Division, FNIH.

Qualification:
The Scientific Program Manager should have a demonstrated ability to:

  • Provide regulatory advice and guidance on gene drive technology to multi-disciplinary, multi-organizational research efforts.
  • Work collaboratively and productively with a wide range of partners, such as research and other technical organizations, regulatory and other government agencies, funding entities, and advocacy organizations both in the U.S. and internationally.
  • Identify, work with and influence individuals at appropriate organizations necessary to achieve the goals of a program.
  • Effectively communicate about complex scientific technology, and the scientific, ethical, regulatory and public considerations for conducting clinical/field trials.
  • Work successfully within a team environment.
  • Manage and meet timelines and milestones.

A doctoral degree in a biological science and demonstrated knowledge of and experience with regulatory science and/or science policy is required.
Preference will be given to candidates with experience in the following areas:

  • Safety and efficacy testing of new biotechnology products.
  • Techniques of synthetic biology.
  • International programs/projects, particularly in Africa.

To Apply:
Please send cover letter and resume to resumes@fnih.org referencing SciTechWS. Please note that only those applications including both a cover letter and resume will be considered.
Cover letter will address the following:

  • Key attributes that denote the applicant's ability to perform the essential functions.
  • Why the applicant fulfills the job qualifications.
  • Why the applicant is interested in working at FNIH in this position.

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Scientific Program Manager, Technical Lead Gene Drive Research

Date Posted:
3/15/2017

Foundation for NIH

MD

Position Description:
This is a professional scientific and administrative management position for an individual with experience and knowledge of the application of genetic engineering and synthetic biology technology for creating products to improve public health. The Scientific Program Manager will participate in the strategic implementation of a portfolio of activities to support the successful introduction of gene drive technologies, with a focus on mosquitoes modified with driving transgenes as tools to control malaria transmission in Africa. The incumbent will provide administrative and technical advice and guidance to individuals and organizations (national and multi-national) with various different roles, responsibilities and interests in gene drive research and its potential deployment. This Scientific Program Manager will be responsible for technical leadership for the FNIH effort.

Essential Functions:

  • Facilitates the establishment and promotion of best practices for safe, ethical, and effective testing of a new and evolving technology. This includes, but is not limited to, planning and coordinating activities aimed at creating a uniform research and development environment for gene drive interventions aimed at malaria control, such as achieving agreement on the necessary product characteristics to contribute to malaria elimination, developing standards for testing of gene drive candidates, and supporting relevant capacity building for field testing at African sites.
  • Collaborates with representatives of funding organizations, academic and other research organizations, communications/advocacy groups, and others to maintain awareness and coordination of a broad range of gene drive research and related activities.
  • Provides technical and organizational leadership for various convenings of gene drive sponsors, supporters and researchers to facilitate collaboration in areas of mutual interest.
  • Represents FNIH at relevant scientific and policy meetings
  • Assists, within a team environment, in designing new projects; creates timelines and resource plans for proposed activities; participates in relevant negotiations; and develops reports to funders and for distribution/publication.
  • Contributes to planning and development of an anticipated, separately funded and sustainable new collaborative enterprise that will play a leadership role in long-term support for the development and implementation of gene drive approaches for malaria control.

The Scientific Program Manager will possess intellectual and scientific skills and knowledge as well as the organizational and administrative abilities to work effectively with a variety of internal and external partners. Recognizing the evolving approaches to and outcomes of research and regulations requirements, and ever-changing attitudes towards gene drive
technology, s/he must be attentive to the rapid pace of technical advances, to proposed changes in policies and regulations and to community and public perception of the technology.
International travel to perform the functions of the Scientific Program Manager is estimated at 10-25% per year.
The incumbent will report to the Director of the Science Division, FNIH.

Qualifications:
The Scientific Program Manager should have a demonstrated ability to:

  • Provide technical advice and guidance to multi-disciplinary, multi-organizational research efforts.
  • Work collaboratively and productively with a wide range of partners, such as research and other technical organizations, regulatory and government agencies, funding entities, and advocacy organizations both in the U.S. and internationally.
  • Identify, work with and influence individuals at appropriate organizations necessary to achieve the goals of a program.
  • Effectively communicate about complex scientific technology, and the scientific, ethical and public considerations for conducting clinical/field trials.
  • Work successfully within a team environment.
  • Manage and meet timelines and milestones.

A doctoral degree with at least three years of relevant research experience (e.g. molecular entomology, field entomology, malaria, product development for mosquito control) and three years of science administration or equivalent experience is required.
Preference will be given to candidates with experience in the following areas:

  • Techniques of genetic engineering and synthetic biology, especially gene drive technology.
  • Basic and/or applied research to develop malaria control tools.
  • International programs/projects, particularly in Africa.
  • International standards for research on genetically modified organisms.

To Apply:
Please send cover letter and resume to resumes@fnih.org referencing SciTechWS. Please note that only those applications including both a cover letter and resume will be considered.
Cover letter will address the following:

  • Key attributes that denote the applicant's ability to perform the essential functions.
  • Why the applicant fulfills the job qualifications.
  • Why the applicant is interested in working at FNIH in this position.
  • Any unique qualities or experience the applicant would bring to the position.

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Assistant Director The Learning Program STEM Transformation

Date Posted:
3/15/2017

Florida International University

FL

Position Description:
The STEM Transformation Institute at Florida International University (FIU) is seeking applications for an Assistant Director of the Learning Assistant (LA) Program. The Learning Assistant (LA) Program is a highly innovative program that fosters implementation of evidence-based classroom practices, engages faculty in course transformation, develops undergraduate students to become facilitators of learning in the classroom and studies the impact of transformations. The Assistant Director (AD) will be involved in all aspects of the LA Program, working closely with the program leaders, undergraduate students, faculty and university administrators. Primary responsibilities include facilitating adoption of the LA model with new faculty and emergent disciplines, including working with faculty and departments to redesign courses to enable best practices in LA-supported courses. Other responsibilities include coordination with other faculty development initiatives and FIU's administration and possibly management of staff. Opportunities for teaching/advising/research may exist. This is a full time, 12-month position, starting as soon as the position filled. Position requires limited travel, primarily to disseminate outcomes of the program.
FIU's STEM Transformation Institute is dedicated to advancing research and educational change that promotes evidence-based instructional practices, utilizing FIU as a laboratory for the future of STEM, as over 75% of FIU's 54,000 students come from traditionally underrepresented groups. The Institute currently hosts 11 discipline-based education research faculty in six STEM departments and 14 staff / postdoctoral researchers that carry out multidisciplinary collaborative work across the Colleges of Arts, Sciences & Education and Engineering & Computing. Hallmark programs include a Learning Assistant (LA) program that impacts well over 13,000 student enrollments in 10 STEM disciplines each semester; Modeling Instruction at the high school and college levels; and multiple HHMI- and NSF-funded research projects. For more information on programs and research at the STEM Transformation Institute: stem.fiu.edu; FIULearn.fiu.edu; FIUteach.fiu.edu. FIU is the public research university in Miami, Florida and is the only majority minority Carnegie R1 research university in the nation.

Qualifications:

  • An earned master or doctorate in science, mathematics, engineering or science/mathematics/engineering education;
  • Minimum 3-years academic experience in teaching and/or in directing academic support experiences;
  • Very strong oral and written communication skills.

Additionally, preference will be given to candidates who demonstrate:

  • Knowledge of recent advances in science, mathematics and/or engineering teaching and learning and/or discipline-based education research (DBER);
  • Experience in supporting course transformation and faculty development;
  • Teaching, advising, and/or administration in higher education;
  • Experience working in collaborative environments.

To Apply:
Qualified candidates are encouraged to attach a cover letter, curriculum vitae and list of three references (with contact information) in a single pdf file and send it to stem@fiu.edu. Note that at least three references may be contacted upon review as determined by the search committee. To receive full consideration, applications and required materials should be received by March 20th, 2017. Applications will be reviewed continually until position is filled. For more information and inquiries emailstem@fiu.edu.


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Future Leaders Program

Date Posted:
3/15/2017

GSK

MD

Program Description:
The Future Leaders Program suits graduates who want a career with real purpose. It's an accelerated development program that equips graduates with the knowledge, skills and attributes to move quickly into senior positions at GSK. Participants benefit from a rich variety of structured training, individual mentoring, and opportunities to experience different aspects of the business. From the start, our challenging rotations will help you deliver the standards of excellence that we'd expect from a future leader.

During the two-year Future Leaders Program you will gain a broad and insightful experience of GSK's vaccines R&D business and the groundbreaking science shaping the organization. The program involves four rotations within different R&D departments, including one abroad. Rotations are chosen to give you the skills, experience and perspective required to succeed in the target leadership position you will step into at the end of the program. Typically, the rotations include time in a hands-on project management role helping to direct the development of a new vaccine, and an external facing position where you will have direct customer contact with healthcare professionals and patients. You will also have the opportunity to see science in action in our labs and learn about the risk and compliance side of vaccine production.
The programme follows the 70:20:10 learning principle: 70% of your learning takes place on the job during your rotations, 20% is the support you'll receive from a senior leader who will be your mentor throughout the program, and the remaining 10% comprises formal leadership training sessions.

What do I need to succeed?

Our Future Leaders need ambition, commercial awareness and a self-motivated, proactive approach. We're looking for clear, effective communicators who can quickly build a rapport with a wide range of people. It's also important that you can adapt to change and keep focused when the pressure is on. While you have the drive and confidence to trust your own judgement, you're a real team player who actively collaborates with others. In addition, you'll need an analytical mind, a talent for multi-tasking and the ability to influence others.

We are looking for candidates who can make outstanding long-term contributions to our organization.
The ideal candidates are driven, curious and can easily build relationships with others; easily adapt to different situations and environments, learn fast, are proactive, result-oriented and driven by challenges and, most importantly, share GSK Values and Expectations.

The benefits of working at GSK Vaccines include innovative projects, passionate people and a truly global business atmosphere. At GSK we provide a supportive working environment, and a range of development challenges and opportunities. We also offer competitive benefits and compensation packages designed to attract and to retain the very best.

Basic Qualifications:

  • Completion of MS, PhD degree in a scientific discipline (ie: biochemistry, biology, microbiology, immunology and pharmacology) by June 2017
  • Possess no more than 2 years of professional experience in the related pharmaceutical/biotechnology industries
  • Masters, PhD: maximum 2 years professional experience after your graduation
  • Post-Doc fellows: maximum 2 years after completion of your PhD
  • Must be eligible to work in the US at the time of, and for the duration of employment. Employees will be required to furnish evidence of US work authorization. Applicant must NOT require future sponsorship for an employment visa status.
  • Willingness to work internationally is required. Ability to be mobile and spend up to 12 months abroad during the program is required.
  • 3.0 GPA or above

Preferred Qualifications:

  • Candidate with a professional degree in Medicine (MD/PhD), Public Health or Business (MBA/PhD)
  • Previous research experience in either the industry or university setting
  • Previous work experience in related pharmaceutical/biotechnology industries, especially with Vaccine development
  • Candidate with working knowledge of French

To Apply:
For more information and to apply online, please click here.


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Scientist I/II Translational

Date Posted:
3/11/2017

Biogen

MA

Scientsit I/II, Translational Sciences
Job Description The Global Biomarker Discovery and Development groups seeking multiple highly motivated scientists to join a dynamic team engaged in the discovery and progression of novel biomarkers for autoimmune and neuroinflammation disease areas. Responsibilities include leading scientific research to identify, evaluate, and characterize relevant fluid biomarkers that will provide useful pharmacodynamic and efficacy endpoints in preclinical and clinical settings. The successful candidate will be capable of multitasking, setting goals, priorities, and planning timelines. Effective communication and collaboration are crucial. Ability to think critically and a commitment to learning are essential.
*Responsibilities:

• Provide strategic input into the identification and validation of novel biomarkers to assist in program progression.

• Develop in vitro assays and technologies to evaluate efficacy, PK/PD relationship, and novel biomarkers that characterize drug candidates for potential therapeutic effects.

• Recognize and troubleshoot data anomalies to ensure high data quality.

• Liaise with cross-functional project teams as the subject matter expert.

• Prepare, review and deliver scientific presentations for internal/external use.

• Learn new techniques and approaches as needed to tackle relevant questions.

• Commitment to help the team achieve deliverables and meet aggressive timelines.

*LI-RD2
Location Cambridge, MA, US
Job Category Research
Requisition Number 30172BR
Qualifications 1. Track record of developing flow cytometry and cell-based assays that interrogate immune function.
2. Familiarity with ligand binding and cell-based assays, utilizing a variety of technology platforms.
3. Excellent assay troubleshooting skills and the ability to identify and evaluate cutting edge assay technologies.
4. Experience in cellular and biochemical science such as standard molecular biology and protein biochemistry techniques (e.g. real-time PCR, DNA cloning, protein purification, Western blotting, immunoprecipitation, enzymatic assays).
5. Background in immunology or neuro-immunology, including experience working in disease areas such as multiple sclerosis, lupus, stroke, or other inflammatory diseases.
6. Hands on experience in the development and validation of biomarker assays in the preclinical and clinical setting is considered a plus.
7. Strong leadership skills and the ability to work independently or with minimal supervision in managing multiple projects and priorities.
8. Ability to collaborate and work in a matrixed environment.
9. Demonstrated record of productivity including providing support activities for multiple research projects and contributing author on peer reviewed publications.
Education PhD with at least 2-5 years postdoctoral research in either an academic or industry setting.
About Biogen Biogen (NASDAQ: BIIB) is a biotechnology leader that discovers, develops and delivers innovative therapies for the treatment of neurodegenerative and rare diseases. Patients worldwide benefit every day from our medicines for multiple sclerosis (MS) and hemophilia.

Founded in 1978, Biogen is one of the world’s oldest independent biotechnology companies. Our development pipeline is focused on areas of high unmet medical need, as we pursue new therapies for patients suffering from diseases with few or no treatment options. These include programs for Alzheimer’s Disease, amyotrophic lateral sclerosis (ALS), Parkinson’s disease, spinal muscular atrophy and neuropathic pain amongst others.

With more than 7,000 people worldwide, Biogen is truly a global organization. We are headquartered in Cambridge, Massachusetts, which is home to our research operations. Our international operations are based in Zug, Switzerland and we have world-class manufacturing facilities in North Carolina and Denmark. We offer therapies globally through direct affiliate presence in 30 countries and a network of distribution partners in over 50 additional countries.

All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.

Please be advised that all legitimate correspondence from a Biogen employee will come from "@biogen.com" email accounts.


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Scientist I Genetics and Genomics

Date Posted:
3/11/2017

Biogen

MA

Computational Biology and Genomics (CBG) is a center of excellence platform line in the Research and Early Development organization at Biogen. The group is responsible for providing genetics and genomics expertise to the R and D organization and specifically applies genetic and genomic discoveries to support Biogen’s drug discovery research clinical development programs. This position will report into the NGS and Genetic Technologies Hub in the CBG organization which provides laboratory support and delivers data to support human disease genetics research projects. We are looking for a PhD level scientist to focus on studying genetics of gene regulation in multiple diseases of interest, and help evaluate, develop and implement novel NGS, RNA and/or DNA technologies to support such studies and other CBG strategic imperatives. The successful candidate will be expected to work closely with Biogen discovery, clinical, and computational scientists to deliver high content genetic and genomic data to impact drug discovery and development activities at Biogen. This individual will employ creative molecular solutions to advance our understanding of the molecular basis of the complex diseases we seek to treat, supporting the discovery of novel potential drug targets, biomarkers, and provide information on drug mechanism of action. As a subject matter expert on specific genomic technologies this role will interface with project teams to provide guidance on application of technologies, experimental design and data interpretation and keep Biogen at the cutting edge of genomic sciences.
Responsibilities

• Develop a program of research in the area of the genetics of gene regulation that will support Biogen’s drug discovery efforts in neurology and rare genetic disease.

• Identify, evaluate and develop novel genomic technologies to advance drug discovery and development activities

• Partner with TA scientists in Discovery Research and Clinical Development team leaders to identify key questions and priorities that novel genetic and genomic technologies can impact

• Deliver high content molecular data for key research projects in CBG

• Identify opportunities for external collaborations that supplement internal CBG resources and ensure genetic and genomic biomarker research is at the cutting edge


*LI-RD2
Location Cambridge, MA, US
Job Category Research
Requisition Number 30157BR
Qualifications PhD in genetics, genomics or a related discipline. Post-doctoral experience is not essential.
• Keen interest in the application of new genetic and genomic technology and deep understanding of human genetics.
• Expertise in NGS technologies and hands on experience developing creative solutions to address biological questions.
• Experience of the evaluation of different genomic technologies.
• Strong collaboration, organizational and communication skills and an ability to work well in a team setting are required.
• The candidate should have be able to work independently have a strong ability to learn and adapt to work on new tasks and projects that he/she may not have worked on previously.
Education Ph.D in Genetics, Genomics or a related discipline

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Scientist Molecular Biology

Date Posted:
3/11/2017

Prothena

CA

The Molecular Biology Research group is seeking a motivated Scientist to join an exciting research team focused on the discovery and development of novel therapeutics for neurodegenerative, inflammatory, and misfolded protein diseases. The qualified candidate must be scientifically driven and will have the opportunity to work in a multi-disciplinary team developing first-in-class antibody therapeutics. The scientist will design, undertake experiments and report preclinical molecular biology study results.

 

Responsibilities:

  • Engineering and expression of monoclonal antibodies and proteins
  • Humanization, optimization, and reformatting of antibodies, including antibody homology modeling and site-directed mutagenesis
  • Molecular cloning of antibodies and protein into expression vectors
  • Antibody/protein expression in bacterial and mammalian cell cultures using shake-flasks and Wave Bioreactors
  • Characterize humanized antibodies using a variety of bioinformatics and biochemical techniques (PAGE & Western blots, ELISA, PCR & qPCR, Fortebio and Biacore etc.)
  • Work closely with other teams to evaluate humanized antibodies in a variety of in vitro and in vivo models
  • Supervise technical staff and facilitate smooth functioning of the lab
  • Maintain accurate and up-to-date records, present results at company meetings and to collaborators, support patent filings and train others in the use of the technology
  • Communicate data internally and in external meetings in oral and written formats
 

Qualifications:

Education and/or Experience:

  • The candidate must have a D. in Biological Science (Molecular Biology, Cell biology, Immunology, Protein Chemistry, Structural Biology) or a related field with at least 5 years of academic and/or industry work experience within antibody discovery

Competencies and Attributes:

  • Strong track record and hands-on experience in contemporary molecular biology techniques, antibody engineering and bioinformatics are required
  • Strong hands-on experience with basic cell biology, mammalian & bacterial protein expression and protein assay techniques is required
  • The ability to manage multiple projects efficiently, to communicate clearly & effectively and work within collaborative environment is essential
  • Well-documented, strong scientific background within molecular biology, antibody research documented in publications in highly regarded journals and/or intellectual property generation
  • Experience in small-scale bioreactor operation for antibody production is a plus
  • Previous experience with affinity screening and binding kinetics assays using label-free (ForteBio/Octate) techniques is a plus
  • Achieve company objectives in accord with the Prothena core cultural values of courageous, creative, selfless and humor
 
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Scientist Product Characterization

Date Posted:
3/11/2017

Teva

PA

Responsibilities

Responsible for assay development as a core competency for biologics development due to the complexity of large proteins.  Maintain a broad understanding of current analytical technologies for biologics development in a regulated environment.  Progress molecules to commercialization.  Manage product and method characterization activities.  Responsible for the development of analytical methods for protein drug substances, preparation of method descriptions and reports, and characterization of proteins by various analytical techniques.  Work as a technical subject-matter expert to support troubleshooting.  Guide or oversee junior associates or scientists to design and execute studies.  Contribute to regulatory filings, CGMP regulations compliance, and responses to Health Authority questions.  Evaluate new and emerging analytical technologies.  Author technical reports and procedures.  Conduct High Performance Liquid Chromatography (HPLC), mass spectrometry, and peptide mapping.

 

Qualifications

Requirements:  This position requires a Ph.D. degree or foreign academic equivalent in Biochemistry, Molecular Biology, or a related field.  Plus 2 years of experience in the job offered or 2 years in a related occupation including Scientist, Researcher, or related biopharmaceutical experience.  Will accept a Master’s degree plus 5 years of experience in lieu of the required education and experience.  Position requires at least 1 year of experience with characterization of proteins, HPLC, and mass spectrometry.  Will accept any suitable combination of education, training, or experience as per the requirements cited herein.  40hrs/week, 8:00AM – 5:00PM.

 

Application Instructions:  To apply, please E-MAIL resume, ensuring to indicate the position reference code for which you are applying (Ref# SPC228EG) to Diane Barnett, Director-Global atDiane.Barnett@tevapharm.com.

 
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Scientist I Immunology

Date Posted:
3/11/2017

Celgene

MA

Summary:

We are currently seeking an innovative scientist with expertise in immunology, inflammation, and autoimmune diseases to join our Immunology & Inflammation Discovery Biology group in Cambridge, MA.  He/she will be expected to contribute ideas for new drug discovery projects, establish state-of-the-art cellular assays and in vivo and ex vivo models to validate therapeutic targets, demonstrate efficacy of lead compounds, perform detailed mechanism of action studies, run a drug discovery program and provide translational biology support to programs as they enter and move through clinical development. 

 

Qualifications and Responsibilities:

  •  Research experience in multiple inflammatory & autoimmune diseases and/or cancer immunotherapy is required.
    Extensive hands-on experience in isolation, culture, and characterization of primary immune cells from human and animal tissues is required.
    Extensive cell-based and biochemical assay development experience with a variety of readout technologies including flow cytometry, ELISA, and immunofluorescence is required. 
    Experience with a variety of in-vivo and ex-vivo models of inflammation, autoimmune and cancer immunotherapy is strongly preferred.  
    The successful candidate will have outstanding experimental design, troubleshooting, and data analysis skills. Experience with laboratory automation and/or bioinformatics would be a plus.
    Excellent communication, presentation, collaboration and organizational skills are required. 
    Able to distill complex issues and clearly articulate innovative solutions
    Ability to demonstrate effectiveness and growth in a fast-paced and dynamic       team environment.
    Some prior experience managing research associates is a plus.

Excellent record of performance and scientific accomplishments as demonstrated by impactful contributions to the scientific community, pipeline contributions, peer reviewed publications and patent applications.
Clear evidence of sustained independent thought and creativity in developing and implementing advanced technology and ideas for new drug discovery projects. 
Individuals with strong leadership, communication skills, and with experience in participating in and/or leading multi-disciplinary project teams are encouraged to apply.
 

 

 

#LI-JT1 - PR

BIO-US PRIORITY


Qualifications

Job Requirements:

This position requires a Ph.D. with 2+ years of post-doctoral experience, or MS with a minimum of 8+ years experience in immunology or a related field in an academic and/or industry setting.  The ideal candidate will have a reputation as a scientific innovator and collaborator, and have an outstanding track record of success.  

 

Celgene is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.

 

Celgene complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Celgene in the U.S.


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Research Scientist Computational in Spain

Date Posted:
3/11/2017

Celgene

INT

Multinational biopharmaceutical company Celgene, world leader in developing new treatments for cancer and inflammatory diseases, has established the Celgene Institute for Translational Research Europe (CITRE®) in Seville, Spain. CITRE is the company’s first dedicated R&D site outside the USA and provides a bridge between Celgene R&D and the European research community.

 

CITRE was founded in 2010, and laboratory research activities began in June 2011. The Institute now houses a team of highly qualified scientific research and administrative staff drawn from Spain and other European member states. The Institute is located in the Cartuja ‘93 Science and Technology Park and its activities focus on Translational Research into new treatments for cancer and other rare and complex diseases.

 

Scientific activities at CITRE comprise three main departments: The Human Diseased Tissue Laboratory (HDTL), the Computational Biology research group, and the Clinical Trials Unit. Onsite facilities include extensive cell culture, flow cytometry, microscopy, genomics, immunohistochemistry, and state-of-the-art computational analysis infrastructure for biomarker discovery and patient stratification.

 

The three groups are inter-linked by the CITRE tissue Biobank, which receives patient tissue samples, obtained from multi-centre Celgene trials managed by the CITRE Clinical Trials Unit in Spain and across Europe, to provide the basis for inter-disciplinary research into biomarker detection, patient selection criteria, and compound mechanisms of action.

 

Together, these components form a Translational Research centre which coordinates and conducts Celgene medical research in Europe, and enables rapid and effective transfer of new developments and discoveries at Celgene to EU patients. Furthermore, CITRE provides a focal point in Europe for collaborative translational research into cancer and inflammatory diseases, with a mission to rapidly deliver new Celgene compounds to the clinic.


Qualifications

 Requirements

 

  • PhD in computational biology / bioinformatics, statistics, computer science or related fields, with a firm grasp of genomics and/or genetics, from a recognized higher-education establishment;
  • Prior experience (3+ years) in analysis and interpretation of -omics data in academic or scientific research scenarios, supported by high-quality publications;
  • Familiarity with protein interaction/regulatory network collections and network/pathway based analysis methods. Experience with single-cell profiling approaches an advantage;
  • Ability to understand and communicate the output of computational biology research to multi-disciplinary scientific teams;
  • Expertise in Linux, statistical programming and data manipulation, using e.g. R/Bioconductor, Matlab, Python, plus good knowledge of contemporary database structures
  • Experience with version control and high performance computing, including cloud computing (e.g. AWS) and cloud HPC ; and
  • Verbal and written English language fluency. Proficiency in Spanish would be advantageous.

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Research Scientist I Phenotypic High Throughput Screening

Date Posted:
3/11/2017

Vertex

CA

Vertex Pharmaceuticals Incorporated seeks a High Throughput Screening Scientist for our San Diego, California location to design, develop, and implement disease translational, complex phenotypic in vitro assays for a variety of disease targets. The successful candidate will utilize the tools of the HTS discipline to reduce these assays to practice in an automated high throughput manner to identify new leads through primary screens or create clinical candidates from MedChem/SAR assays. The successful candidate will be expected to utilize assay measurement technologies of protein function in disease relevant cells and to contribute to identifying novel pharmacological and physiological insights to drug discovery.   Experience in developing cell based assays in the therapeutic areas of neuroscience, pain and ion channel biology/pharmacology is highly preferred. The successful applicant will contribute cell biology and ion channel/receptor pharmacology expertise to discovery projects and play a key role in the identification of chemical matter for novel targets and/or pathways for drug discovery.  

Requirements

Minimum Qualifications
•   Ph.D. in Cellular Biology, Pharmacology or related field with three years or more years of post-doctoral experience working with cellular assay development and pharmacology.
•   Experience involving the design, optimization and validation of target and phenotype based automated high throughput screening assays  
•   Demonstrated understanding of data analysis packages for automated high throughput screening, statistics and QC principles
•   Demonstrated ability to independently execute studies and provide reports and results to major stakeholders
•   Effective communication skills, both verbal and written, with the ability to present data at project team or other meetings as appropriate are essential
•   Demonstration of above experience through first author publications in high impact peer reviewed journals is expected.


Preferred Qualifications
•   Experience with ion channel pharmacology and electrophysiology
•   Development of model cellular systems; 3D co-cultures; induced pluripotent stem cells
•   Developing highly novel cellular screening approaches employing high content imaging, multi-parametric FACS and/or imaging analysis.  
•   Ability to navigate and be successful in a fast-paced, highly-matrixed work environment is preferred
•   A strong desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families, and society is preferred


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Research Scientist I Chemical Biology

Date Posted:
3/11/2017

Vertex

CA

Vertex Pharmaceuticals Incorporated is seeking a Research Scientist I for an exciting opportunity within its cross-functional chemical biology group.  The successful candidate would have a proven expertise in bio-conjugation methods and state of the art fluorescence detection and dye synthesis.  The preferred candidate would have a strong synthetic chemistry background and able to comfortably work at the interface between organic chemistry, molecular biology, and protein biophysics.  The successful candidate will be able to work independently, be able to multi-task, be able to work collaboratively in teams, and be adaptable to changing needs.  A strong desire to grow as chemist and the courage to challenge conventional wisdom are essential.
 
 
- Master’s degree in organic synthesis
- 3+ years of relevant experience applied fluorescence and/or bioconjugation methods
- Organize efforts to stay consistent with project priorities
- Demonstrated effective communication skills, both verbal and written to a broad range of audiences
- Ability to navigate and be successful in a fast-paced, highly-matrixed work environment
 
Preferred Qualifications:
- Ph.D. in organic synthesis
- 0-3 years of relevant experience applied fluorescence and/or bioconjugation methods
- A desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families and society

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Research Scientist II Elctrophysiologist

Date Posted:
3/11/2017

Vertex

CA

Vertex Pharmaceuticals Incorporated is offering an exciting opportunity to join the Pharmacology Group with a focus on the development of novel therapeutics. We are seeking a motivated, creative and innovative electrophysiologist with a deep understanding of ion channel biophysics and broad, hands-on experience using in vitro cellular electrophysiology techniques, with a particular focus on manual patch clamp, single channel recording and mechanism of action of ion channel pharmacology. A successful candidate will have demonstrated scientific expertise in ion channel function, measurement of ion channel activity, and application of electrophysiological recording techniques to characterize compound mechanism of action in support of drug discovery programs. 

Key responsibilities:
- Execute ion channel electrophysiology studies to elucidate the mechanism of action of compounds and mutations on channel behavior to support drug discovery projects.
- Analyze and interpret data and effectively document and communicate results.
- Provide technical expertise in ion channel biophysics and single channel and whole cell patch clamp electrophysiology.- Work effectively in a multi-disciplinary team environment and have excellent organizational and communication skills. 


Minimum Qualifications:
- Ph.D. (or equivalent) in Physiology, Pharmacology, or a related field with 2-5 years of drug discovery experience, preferably in a pharmaceutical/ biotechnology setting, or MS (or equivalent) in similar field with 5+ years of similar experience, or- BS (or equivalent) in similar field with 8+ years of similar experience.
- Extensive knowledge of ion channel biophysics and applications to drug discovery.
- In depth experience in the design, execution and interpretation of manual and/or automated patch-clamp electrophysiology studies.- Effective communication skills, both verbal and written.

Preferred Qualifications:
- Experience with CFTR chloride channels and epithelial ion transport is preferred.
- Ability to navigate and thrive in a fast-paced, highly-matrixed work environment.
- Strong desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families, and society.
 
Vertex is a global biotechnology company that aims to discover, develop and commercialize innovative medicines so people with serious diseases can lead better lives. In addition to our clinical development programs focused on cystic fibrosis, Vertex has more than a dozen ongoing research programs aimed at other serious and life-threatening diseases.

Founded in 1989 in Cambridge, Mass., Vertex today has research and development sites and commercial offices in the United States, Europe, Canada and Australia. For four years in a row, Science magazine has named Vertex one of its Top Employers in the life sciences. For additional information and the latest updates from the Company, please visit www.vrtx.com.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

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Research Scientist I Stem Cell Biology

Date Posted:
3/11/2017

Vertex

CA

Vertex Pharmaceuticals is seeking a highly motivated human cell biologist to join the Human Stem Cell Group. The successful candidate will be responsible for derivation and culture of adult progenitor and stem cells to support gene editing programs. Additional responsibilities also include optimization of differentiation protocols, development of transfection and transduction protocols, cell characterization using gene expression and protein labeling techniques. The successful candidate should also have an experience with human IPSCs culture and differentiation into neuronal and other lineages. He/She should be a highly motivated, hard-working person with good knowledge of cellular and molecular biology.


·    M.S. in cell biology, molecular biology or related area
·    Minimum 3 years of extensive hands on experience working with human primary stem cells and/or human IPSCs
·    Proficiency incell biology, histology and basic molecular biology techniques
·    Experience with viral transduction of human primary cells
·    Experience in FACS analysis
·    The successful applicant must be results orientated, self-motivated, and well-organized
·    Effective communication skills, both verbal and written
·    Exceptional multitasking skills, ability to work and deliver on several projects simultaneously
·    Ability to work independently and as part of a team in a matrix organization, ability to adapt to a time-line driven work environment
 
Preferred Qualifications:
·    PhD in cell biology or related area
·    Proven record of scientific accomplishments working with human stem cells
·    Basic understanding of the use of human cells in drug discovery processes is a plus
·    Experience in working in an industry environment is desired
·    A desire to be part of a highly innovative company that aims to transform the lives of people with serious diseases, their families, and society

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Scientist Cell Biologist

Date Posted:
3/11/2017

Vertex

MA

Vertex Pharmaceuticals is searching for an outstanding human cell biologist with a strong scientific background and proven accomplishments in deriving and differentiating human iPS cells into a variety of cell types (in particular neural cell types) for target validation, proof-of-concept experiments, and drug screening.   The ideal candidate will be responsible for the generation, maintenance, differentiation and characterization of human pluripotent stem cell-derived lines.  Extensive hands-on experience in working with primary human cells (especially neural cells), developing complex functional assays, high content imaging, and implementing quantitative image analysis using commercial and open-source software is preferred. The applicant will be part of a fast-paced drug discovery team. Good communication and people skills are required.


Key Responsibilities:


·     Reprogramming somatic cells to iPS cells and differentiating iPSC to various cell lineages


·     Characterizing differentiated cell populations by FACS, qPCR, and multi-electrode array


·     Develop and optimize high-content imaging protocols; experience with the Molecular Dynamics ImageXpress and Cellomics Arrayscan platforms (or systems of similar capacity and complexity) is preferred.

Minimum Qualifications

·     The ideal candidate will have a Ph.D. in Neurobiology or related science and minimum of 2-3 years of experience in primary human and stem cell biology and assay development


·     Strong technical background in neuroscience and imaging is preferred


·     Experience with iPS cell growth and differentiation particularly in feeder-free conditions is required; history with iPSC-derived cell-based assay systems is preferred


·     Excellent multi-tasking skills, attention to detail and ability to work independently are required


·     Excellent communication skills and ability to work in a highly-collaborative team environment


·    A desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families and society 


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Postdoctoral Fellow

Date Posted:
3/11/2017

Alexion

MA

Position Summary

 We are seeking a Postdoctoral Scientist to develop quantitative systems pharmacology (QSP) models of complement proteins and their role in disease pathobiology. The successful candidate will be an excellent cross-disciplinary scientist who uses cutting-edge modeling and simulations technologies to shed light on underlying pharmacological pathways, and has in-depth knowledge of using computational insights to design, execute and analyze critical experiments.  The Postdoctoral Scientist will integrate data from published literature and in-house experiments to build innovative QSP models of complement driven diseases and apply emerging insights to investigate novel protein targets. In addition, s/he will work closely with Alexion colleagues as well as with Key Opinion Leaders in the field of complement and coagulation biology. 

Principal Responsibilities

  • Build QSP models of complement pathways and their role in underlying disease pathobiology
  • Mine published literature to obtain and evaluate experimental data from in-vitro and in-vivo studies on complement systems. Stay current on published literature.
  • Collaborate with Alexion complement experts to develop a keen sense of experimental work being performed, identify data gaps and facilitate design of new experiments towards model refinement.
  • Ensure well annotated model codes with appropriate documentation for future use.
  • Present data at internal and external scientific meetings, and publish in major scientific journals

Qualifications

  • Ph.D. in bioengineering, biochemical engineering, computational biology or related field.
  • Experience in building ODE based systems pharmacology models.
  • Experience in using computational tools to design critical experiments.
  • Excellent oral and written communications skills with proven talent in communicating complex mathematical insights to biologists and clinicians.
  • Independent thinker and self-starter with talent in collaborating with multi-disciplinary teams.
  • Record of significant publications in top peer reviewed journals and presentations at major scientific meetings (preferably as first author).

Education

  • Ph.D. in bioengineering, biochemical engineering, computational biology or related field.

*LI-MW1 

 

Lexington, MA, United States
 

 

Alexion is a global biopharmaceutical company focused on developing and delivering life-transforming therapies for patients with devastating and rare disorders. Alexion developed and commercializes Soliris® (eculizumab), the first and only approved complement inhibitor to treat patients with paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS), two life-threatening ultra-rare disorders. As the global leader in complement inhibition, Alexion is strengthening and broadening its portfolio of complement inhibitors, including evaluating potential indications for eculizumab in additional severe and ultra-rare disorders. Alexion’s metabolic franchise includes two highly innovative enzyme replacement therapies for patients with life-threatening and ultra-rare disorders, Strensiq® (asfotase alfa) to treat patients with hypophosphatasia (HPP) and Kanuma™ (sebelipase alfa) to treat patients with lysosomal acid lipase deficiency (LAL-D). In addition, Alexion is advancing the most robust rare disease pipeline in the biotech industry, with highly innovative product candidates in multiple therapeutic areas.
As a leading employer in our industry, Alexion is proud to offer a highly competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, 401(k) with company match, tuition reimbursement, relocation assistance and much more. To learn more about Alexion, please visit www.alexionpharma.com or download our App for iPhones and Blackberries.

Alexion is an Equal Opportunity /Affirmative action employer

Alexion participates in E-Verify process. To learn more, please click on attached document(s)

English/Spanish


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Computational Scientist

Date Posted:
3/11/2017

Evelo

MA

Computational Scientist

 

Evelo Biosciences is seeking an experienced Computational Scientist to join our talented and dedicated team of scientists and engineers in changing the lives of patients around the world in a fast-paced environment. The successful candidate will drive the use of computational approaches to advance cutting-edge programs and the discovery and validation of novel targets and biomarkers in preclinical and clinical drug discovery and development. Must have a deep passion for improving health outcomes for patients.

 

Responsibilities:

 

The successful candidate will advance Evelo’s pipeline in discovery, preclinical and clinical stages by accomplishing the following:

  • Collaborative with therapeutic area scientists and clinical researchers in applying state-of-the art informatics and data mining approaches
  • Design and execute on the analysis of in vivo and in vitro experiments
  • Design and execute on the analysis of in silico experiments
  • Identify and evaluate external collaborators, novel methods and emerging expertise
  • In-depth characterization of cellular and human microbiome responses in preclinical and clinical models
  • Share and contribute scientific and technical know-how and experience with team members

 

Qualifications:

  • D. in a relevant scientific discipline or technology area, particularly in Computational Biology, Computer Science, Data Science
  • In-depth knowledge and extensive hands-on experience with genomics, metagenomics, microbiome or electronic medical records
  • Minimum of 5 years of post-graduate or biotech/pharma experience in analyzing large data sets with advanced analytics approaches
  • Hands-on experience with scientific computing capabilities including high performance computing (HPC), bioinformatics pipelines, natural language processing and machine learning
  • Versed in traditional and emerging mathematics and methods to model high dimensionality data sets
  • Knowledge of the pharmaceutical drug discovery and development process with a relevant track record, including preclinical and clinical drug development
  • Proven track record of scientific accomplishment and contributions to the field of computational sciences
  • Exceptional scientific reporting and presentation skills in translating complex statistical methods into readily understood and valuable results
  • Demonstrated ability to work collaboratively with research project teams and clinical development teams
  • Dynamic, flexible, well-organized, pro-active, collaborative-minded individual passionate about improving health outcomes for patients around the world

 

 

 


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imuunologist

Date Posted:
3/11/2017

Evelo

MA

Evelo is seeking an experienced Scientist to join our Immunology research team to advance cutting-edge microbiome therapeutic programs. This role will provide Immunology expertise towards developing targeted, microbe-based, immune tolerizing and anti-inflammatory therapeutics to enable successful IND filings. This individual will support and expand our research strategy to conceptualize, design and execute pivotal in vitro and in vivo proof of concept studies in pre-clinical models of autoimmunity and inflammation. Significant cross-functional collaboration with a talented and dedicated group of scientists including microbiologists, cell biologists and  immunologists, will ensure a diverse exposure to the drug discovery process.

 

Responsibilities:

The successful candidate will advance several aspects of Evelo’s lead preclinical microbial therapeutic programs, using their targeted skill set to accomplish the following responsibilities:

  • Design and execution of well-controlled in vitro and in vivo immunologyexperiments
  • In-depth characterization of cellular and humoral immune responses in various mouse models of autoimmunity, inflammation and immune tolerance in general
  • Develop, execute, and trouble-shoot immunoassays, including in vitro cellular stimulations, flow cytometry, ELISA, and microscopy
  • Share and contribute scientific and technical know-how and experience with team members

 

Qualifications:

  • D. in the domain of immunology, preferably with focus in autoimmunity, inflammation, tolerance, or vaccines.
  • 3-6 years of post-doctoral or biotech/pharma experience in developing and conducting laboratory research
  • In-depth knowledge and extensive hands-on experience in mouse models of cellular autoimmunity, primary immune cell characterization, immunoassay development, and protein chemistry
  • Proven track-record of scientific accomplishment and contributions to the field of autoimmunity or tolerance research
  • Exceptional scientific reporting and documentation proficiency
  • She or he should be a dynamic, independent, flexible, well-organized, pro-active, collaborative-minded individual interested in contributing in a hands-on and strategic role to excellent research science in a fast-paced entrepreneurial environment.

 


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in vitro immunology

Date Posted:
3/11/2017

Evelo

MA

 In Vitro Immunology Scientist 

 

Evelo Biosciences, founded by Flagship VentureLabs has established the leading therapeutics discovery and development based on the human immuno-microbiome. We are developing onco-microbials for the treatment of cancer and immuno-microbials for the treatment of autoimmune and inflammatory diseases.

 

We are seeking talented and dedicated Scientists, who are  interested in joining a highly dynamic and intellectually challenging team. This exciting role will afford Scientists the opportunity to be intimately involved in the implementation of cutting-edge research programs in a multifunctional biology laboratory.   Successful candidates will posses expertise in immunology and/or immuno-oncology and a proven ability to multi-task within scope. 

 

Primary responsibilities:

 

- Design and conduct in vitro immune cell-based assays for screening, discovery, and mechanistic analysis of microbial drug candidates

- Design and implement rigorous ex vivo assays to understand immunological mechanism of action 

- Develop and implement multi-parameter flow cytometry-based immune phenotyping assays, cell sorting assays, and multiplex cytokine profiling assays

- Actively participate on project teams and collaborate across interdisciplinary R&D programs

-Independently design rigorous experiments, interpret data, and communicate findings in well-articulated presentations

 

Desired capabilities, skills and experience:

 

- Candidates must have a background in immunology, immuno-oncology, drug discovery with experience in microbiome field a plus

- Proficient in flow cytometry techniques, cytokine/chemokine profiling on Luminex or similar platform

- Experience with primary mammalian cell culture, cell proliferation assays, and/or metabolic assays

- Experience with ex vivo rodent sample processing, including RNA/DNA extraction, immunophenotyping, and immunohistochemistry

- Highly motivated and results driven individual with a passion for working in a fast-paced and evolving organization

- Strong oral and written  communication as well as excellent collaboration & interpersonal capabilities

- Outstanding team player with ability to work in groups as well as independently 

- Adept at problem solving

 

Education and experience requirements:

 

- Ph.D. in immunology or related field

- 3-5 years of relevant experience in biopharmaceutical industry strongly preferred

 


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Scientific Strategy Corporate Development Fellowship

Date Posted:
3/11/2017

Evelo

MA

Evelo Biosciences is dedicated to transforming immunotherapy therapy through a deep understanding of the immuno-microbiome, the intimate coevolved metasystem of the host immune system and the microbiome.  Evelo is developing therapies designed to treat cancer, inflammatory, and autoimmune disease through modulating the systemic immune system.  Evelo’s platform deciphers microbes’ ability to modulate local and systemic immune function, evaluates microbes’ efficacy in disease models, and creates pharmaceutically acceptable forms of microbes for development and clinical translation.  Evelo was founded in 2015 by Flagship VentureLabs®, the innovation foundry of Flagship Pioneering. Evelo has an initial capital commitment of $100+ million and is considered to be one of the most exciting companies in the microbiome space today.

 

2017 SUmmer fellowship

Evelo is seeking a talented PhD or MD student or post graduate to join us for the summer of 2017. Evelo is a highly dynamic and intellectually challenging work environment.  The successful candidate will be a self-starter, scientifically and intellectually curious, entrepreneurial, and a creative problem solver.

 

Fellow will partner closely with Evelo’s Head of Scientific Strategy on a variety of projects, including:

  • Surveillance of scientific fields and sourcing interesting and innovative technologies from academia
  • New program planning and product building, including the drafting of R&D plans
  • Intellectual property strategy related to Evelo’s current and future products
  • Regulatory strategy and clinical translation of Evelo’s products

 

Program Details

  • Full-time Fellowship from June 6, 2017 – September 1, 2017
  • Fellow will be based out of Evelo’s headquarters at 620 Memorial Drive, Cambridge, MA
  • Fellow will receive a stipend

 

Fellows will be able to

  • Influence a growing biotech
  • Expand professional network
  • Develop marketable skills for careers in the commercialization of science

 

Qualifications

  • Current PhD, MD, or MDP student or post-graduate
  • Demonstrated passion and business acumen for translation and commercialization of science
  • Clear communication skills, creativity, and independence
  • Deep scientific or business background in the life sciences
  • Knowledge and expertise in immunology, cancer biology, neurobiology, or microbiology a plus

 

Please submit your cover letter and resume at: https://evelobio.recruiterbox.com/jobs/fk06qcg

For more information about Evelo Biosciences, please visit http://www.evelobio.com


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Biomedical Engineer

Date Posted:
3/10/2017

Kelly Services

CA

Biomedical Engineer Location: San Jose, CA Contract Position Job Description: Our Advanced Sensors Group is expanding and looking for a bio-sensor engineer with bio-medical and optical sensor experience. He/she will be working closely with cross functional team across company for successful product development. Candidate will also be a core member of the team and will be providing status updates to customers, as well as top level executives. Lead R&D efforts for design of bio-medical optical sensors. Develop thorough understanding of human body physiology, focused for wearable sensors technology. Understand optimizations, trade-offs, error sources, human population variations with respect to biological signal of interest. Communicate and educate cross-functional team on design choices, optimization and design pit-falls As part of the product definition team develop optical and electrical requirements for the proposed sensing solution. Advice groups on possible solutions of ongoing sensor focusing on bio-medical issues Qualifications: PhD degree relative to Bio-Sensors, preferable with tissue optics experience 5+ years of experience in the design of sensor systems. Preferably in wearables. Understanding of human physiology, Tissue Optics and its challenges. General modeling and analysis of systems. Experience in MATLAB, Solidworks/Autocad (preferred) Experience is data collection, data analysis, understanding trends and error sources Provide direction to user studies group for repeatable and accurate user data that is essential to algorithm development. Lead R&D projects on creating future products. Excellent written and verbal communication skills. Travel Requirements – 10-20% International and domestic.


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Biologists and Chemists multiple positions

Date Posted:
3/10/2017

Kelly Government Solutions

OH

BS, MS, PhD Biologists and Chemists - Government Research Facility - Columbus, OH Kelly Government Solutions is a strategic supplier and business partner to the federal government and its key suppliers. We are currently seeking BS, MS, and PhD Scientific Analysts to provide support of a new cutting edge laboratory based technology in Columbus, OH. These multiple government contract positions are: -Contract length: not known at this time. -Contract Hours: Full time and Part time opportunities (25- 40 hours/week) / flexible schedules. -May require some weekend and evening work based on projects. -Benefits are available to purchase through Kelly Services due to the Affordable Care Act. TASKS/SERVICES: The contractors shall: 1. Perform literature reviews and summaries of reviewed information related to the new technology, with subsequent preparation of protocols for technology use. 2. Participate in experimental execution of the technology in lab, with subsequent data reduction, data review, and data compilation adhering to accepted practices. 3. Log daily activities during literature review and laboratory efforts. 4. Work independently in a laboratory environment, displaying an interest in successfully achieving the goals of the technology research and implementation. 5. Maintain good work attendance record and be punctual for all project work. REQUIREMENTS: The contractors must have: 1. PhD in Chemistry, Microbiology, and/or Molecular Biology with 5-10 years of experience in a lab-based facility. MS or BS in Chemistry with 1+ years of experience in a lab-based facility are also welcome. 2. Proven ability to conduct experiments according to provided procedures. 3. Ability and willingness to work in biological laboratories and adhere to established safety guidelines. 4. Sufficiently medically fit to work in the laboratory to perform assigned duties. 5. Proficient with Microsoft Windows operating system and Microsoft Office, as well as general online research capabilities (use of search terms, etc). 6. Must be eligible to obtain security clearance. 7. Strong verbal and written communications skills; strong attention to detail. PLEASE APPLY ONLINE Note that the phone number for our Kelly Scientific branch is not listed. Due to the high volume of inquiries, we regret that we cannot accept phone calls. All qualified candidates will be contacted.


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Scientific Grants Program Analyst

Date Posted:
3/10/2017

Kelly Government Solutions

MD

Scientific Grants Program Analyst - NIH - Bethesda, Maryland Kelly Government Solutions is a strategic supplier and business partner to the federal government and its key suppliers. Through our partnership with the National Institutes of Health, Kelly Government Solutions offers administrative, IT, engineering, scientific, and healthcare professionals the opportunity to work with one of the most prestigious research organizations in the world. We are currently seeking a GRANTS PROGRAM ANALYST to work on-site at the National Institutes of Health in Bethesda, MD. Bethesda is near Washington, DC. This is a full time, long-term contract position which offers: - Competitive salary with comprehensive benefits package - Opportunity to work at NIH, the world's foremost medical research center - Learn more about what Kelly can do for you at www.kellygovernmentsolutions.com National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) National Institutes of Health (NIH) Bethesda, Maryland Administrative position TASKS/SERVICES. The contractor shall: 1. Identify scientific and management issues and policies related to designated programs. 2. Identify policy issues that impact MoTrPAC (the Molecular Transducers of Physical Activity Consortium); work with Program staff to determine appropriate approaches and positions for handling these issues. 3. Contribute to the creation of programmatic documents. 4. Prepare materials such as handouts to advertise the availability of MoTrPAC resources for the research community, posters for scientific meetings, and PowerPoint presentations for senior program leadership. 5. Create content for the NIAMS-specific projects and NIH Common Fund program websites. 6. Read, interpret, analyze and condense scientific material from a variety of sources for presentation. 7. Work with extramural program directors and other staff to compile a report of ongoing and emerging scientific areas; create search criteria for locating scientific, program and related information on the internet and through internal NIH database searches. 8. Develop meeting agendas for MoTrPAC working group meetings and related meetings. 9. Attend and support NIH Common Fund staff, working group, Project Team and Steering Committee meetings. 10. Devise methods to ensure operational plans are developed by the appropriate staff to help implement scientific priorities and policies; track action items and tasks; provide deadline reminders to Program staff; maintain spreadsheets of relevant information. 11. Maintain a running document of milestones, timelines, deliverables and deadlines related to the MoTrPAC. 12. Develop reporting templates for gathering scientific and programmatic information re-lated to the MoTrPAC and other extramural research activities. 13. Track receipt of MoTrPAC steering committee reports; edit and finalize materials for submission to the NIH Office of Strategic Coordination. 14. Gather meeting minutes and assist with organizing specific MoTrPAC work stream tel-econferences with the aim of keeping MoTrPAC on track and on schedule. 15. Verify accuracy of human subjects enrollment data from Interim Reports; enter information into Population Tracking tables into the NIH eRA module. 16. Run QVR searches as part of an analysis to measure the impact of NIH-funded programs, including the MoTrPAC; generate and analyze data to produce spreadsheets and graphs for use by program staff. 17. Proofread and edit outgoing materials, including Program and Funding Opportunities Announcements and press releases, to ensure that requested changes have been made. 18. Review, monitor, analyze and evaluate financial, narrative and statistical reports and scientific and programmatic data submitted to NIH by grantees and contractors. 19. Determine accuracy of information to develop SOPs. 20. Update statistical data from grant applications. 21. Collaborate with staff to develop daily, short- and long-range direction for assigned programs and special projects. 22. Remain alert to program progress and effectiveness and work with staff to adjust the approach or direction and priorities of assignments. 23. Develop and implement measures to ensure coordination within the NIAMS, and within other NIH organizations affected by assigned programs, including MoTrPAC. REQUIREMENTS. The contractor must have: 1. Master’s degree in Science or related with 3+ years of experience in TASKS above. 2. Bachelor's degree with 5 years of experience will be considered. 3. Excellent proactive, proven project management and problem solving skills. 4. Expertise in effective/efficient meeting management and administrative tasks. 5. Strong analytical, communications skills, both verbal and written. 6. Excellent leadership, analytical, organizational and time management skills. PLEASE APPLY ONLINE. Note that the phone number for our NIH branch is not listed. Due to the high volume of inquiries, we regret that we cannot accept phone calls or emails. All qualified candidates will be contacted.


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Biochemist

Date Posted:
3/10/2017

Kelly Government Solutions

MD

Biochemist - NIH - Bethesda, Maryland Kelly Government Solutions is a strategic supplier and business partner to the federal government and its key suppliers. Through our partnership with the National Institutes of Health, Kelly Government Solutions offers administrative, IT, engineering, scientific, and healthcare professionals the opportunity to work with one of the most prestigious research organizations in the world. We are currently seeking a BIOCHEMIST to work on-site at the National Institutes of Health in Bethesda, MD. Bethesda is near Washington, DC. This is a full time, long-term contract position which offers: - Competitive salary with comprehensive benefits package - Opportunity to work at NIH, the world's foremost medical research center - Learn more about what Kelly can do for you at www.kellygovernmentsolutions.com National Heart, lung and Blood Institute (NHLBI) Intramural Administration Management Branch (IAMB) Imaging Probe Development Center (IPDC) National Institutes of Health (NIH) Bethesda, Maryland Main Campus, lab position TASKS/SERVICES. The contractor shall: 1. Culture and maintain cells for in vitro assays. 2. Perform in vitro radioligand binding assays and immuno assays. 3. Conduct experiments including performing synthetic, optical, radionucleotide and biochemical studies; produce known and novel agents. 4. Support in vivo biodistribution studies. 5. Purify proteins and bioconjugation of fluorescent and chelating groups. 6. Collaborate with chemists within Imaging Probe Development Center (IPDC) for the preparation and testing of synthesized probes. 7. Produce intermediaries and final products in pre-determined amounts and purities. 8. Perform analytical validation and testing of compositions. 9. Propose novel solutions to problems encountered during research; develop and present plans for solutions. 10. Perform literature searches in support of research. 11. Collect, analyze and interpret data and findings. 12. Prepare summaries and reports based on findings and results. 13. Attend meetings and present results and findings to staff. REQUIREMENTS. The contractor must have: 1. MS in Biochemistry or related with 4+ years of experience as described in TASKS. 2. BS with 6 years of experience will be considered. 3. Experience in tissue culture techniques and in vitro assays. 4. Ability to understand software packages for KD determination. 5. Strong verbal and written communications skills. 6. Excellent analytical, organizational, interpersonal and time management skills. PLEASE APPLY ONLINE. Note that the phone number for our NIH branch is not listed. Due to the high volume of inquiries, we regret that we cannot accept phone calls or emails. All qualified candidates will be contacted.


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Experimental Therapeutics Program Analyst

Date Posted:
3/10/2017

Kelly Government Solutions

MD

Experimental Therapeutics Program Analyst *** NIH *** Rockville, MD Kelly Government Solutions is a strategic supplier and business partner to the federal government and its key suppliers. Through our partnership with the National Institutes of Health, Kelly Government Solutions offers administrative, IT, engineering, scientific, and healthcare professionals the opportunity to work with one of the most prestigious research organizations in the world. We are currently seeking an Experimental Therapeutics Program Analyst to work with the National Institutes of Health in Rockville, MD. This is a long-term contract position which offers: - Competitive salary with comprehensive benefit package - Opportunity to work at NIH, world's foremost medical research center - Learn more about what Kelly can do for you at www.kellygovernmentsolutions.com TASKS/SERVICES : The contractor shall: (1) Provide support for activities of the National Cancer Institute's (NCI) Experimental Therapeutics (NExT) Program to develop novel molecularly targeted agents for cancer through the Chemical Biology Consortium (CBC) discovery pipeline. (2) Work with staff on the evaluation, review and prioritization of drug discovery/development projects within the NExT/CBC portfolio. (3) Provide day-to-day decisions necessary to meet drug discovery/development project objectives with project leaders and portfolio managers. (4) Work with staff on the coordination and conduct of meetings with project teams, project managers, NCI senior management staff, and external experts. (5) Develop and review discovery/development project plans with project managers, project leaders, and portfolio managers. (6) Provide analysis, advice and ideas about drug targets and pathways to Special Assistant to the Director of the Division of Cancer Treatment and Diagnosis. (7) Prepare reports, proposals and presentations. REQUIREMENTS : The contractor ideally would have: (1) Ph.D. in Molecular Biology, Medicinal Chemistry, Developmental Therapeutics, Oncology, Biomedical Research, Pharmacology, or a related discipline. (2) Previous experience in research and/or administrative experience in an academic setting or in a pharmaceutical, biotechnology, or medical device industry. (3) Understanding of the basic fundamentals of project and portfolio management. (4) Knowledge of SBIRs and grant application/review process. (5) Knowledge of medicinal chemistry and drug design. (6) Proficiency in Microsoft Office Project and Microsoft Office Suite (MS Word, Excel, PowerPoint, Outlook), SharePoint and other data management systems. (7) Highly effective problem solving, planning and organizational skills. (8) Excellent people skills and strong communication skills, both oral and written. (9) Ability to function collaboratively within a team setting. (10) Attention to detail and follow through. PLEASE APPLY ONLINE Note that the phone number for our NIH branch is not listed. Due to the high volume of inquiries, we regret that we cannot accept phone calls. All qualified candidates will be contacted.


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Scientific Program and Communications Analyst Cancer Diagnosis Center

Date Posted:
3/10/2017

Kelly Government Solutions

MD

Scientific Program and Communications Analyst *** NIH *** Rockville, MD Kelly Government Solutions is a strategic supplier and business partner to the federal government and its key suppliers. Through our partnership with the National Institutes of Health, Kelly Government Solutions offers administrative, IT, engineering, scientific, and healthcare professionals the opportunity to work with one of the most prestigious research organizations in the world. We are currently seeking a Scientific Program and Communications Analyst to work with the National Institutes of Health in Rockville, MD. This is a long-term contract position which offers: - Competitive salary with comprehensive benefit package - Opportunity to work at NIH, world's foremost medical research center - Learn more about what Kelly can do for you at www.kellygovernmentsolutions.com TASKS/SERVICES : The contractor shall: Communications (1) Work with staff to coordinate projects, events, activities and initiatives within the Cancer Diagnosis Program (CDP). (2) Help manage the communications effort for the Cancer Diagnosis Program. (3) Design and coordinate systems for communication among staff to facilitate the efficient flow of information relating to projects and program activities, including databases and the use of SharePoint. (4) Coordinate the preparation of a variety of documents such as outside activities (Form520), training requests, individual/mass mailings, correspondence, reports and various other forms. (5) Develop a plan to improve the outreach, education, and interaction strategies of CDP. (6) Implement the plan to ensure that the communications goals are met. (7) Manage the Cancer Diagnosis Program (CDP)/ Biorepositories and Biospecimen Research Branch (BBRB) Listserv and use it to promote news, announcements and other relevant information of the office. (8) Work with the Office of Communications and Public Liaison to achieve the communications goals of CDP. (9) Develop new educational materials for CDP stakeholders, including patients, researchers and healthcare professionals. (10) Manage the CDP public website & the BBRB public website, including developing content, and general administrative duties. (11) Lead efforts to improve the CDP website so that it can better meet the use and the goals of the communications plan. (12) Lead efforts to gather new content from CDP staff to keep the websites up to date and to develop timely content for the website. (13) Manage social media accounts for CDP (including but not limited to Twitter, LinkedIn, etc.). (14) Lead efforts to expand the use of social media. (15) Develop and implement a plan to use social media channels to keep CDP stakeholders and the research community informed and up to date. Administrative (1) Attend internal/external meetings and scientific conferences; coordinate logistical planning for meetings/teleconferences; take notes and prepare minutes for scientific meetings related to Cancer Diagnosis meetings and programs. (2) Schedule and make arrangements for meetings and events within and outside CDP; reserve space; set schedule and times; contact participants; transmit agenda and materials for discussion. (3) Prepare and finalize meeting agendas and other materials based on staff and consultant input. (4) Prepare and distribute presentation materials such as reports, summaries, tables, graphs and slides. (5) Take a proactive role in tracking action items and tasks; provide deadline reminders to staff; maintain spreadsheets of relevant information for grants, contracts and other programs. (6) Request information from and provide e-mail, phone and written responses to NCI staff, NIH staff, other government agencies and community members. (7) Prepare presentations, reports, summaries, databases and other documents related to the accumulation and analysis of data. (8) Respond to inquiries and requests for general information from internal and external sources. (9) Manage the CDP SharePoint site. (10) Work with staff to ensure that new staff members are granted appropriate permissions to the CDP SharePoint site. (11) Troubleshoot issues with SharePoint use. (12) Manage and create new sections of the SharePoint site as needed. (13) Serve as the Lead Safety Coordinator for Safety and Security. Database Management (1) Develop tools using programs such as Excel, SharePoint, Access and Filemaker to create usable databases for CDP staff for grants, contracts, clinical protocols and reviews of same. (2) Manage various databases in Microsoft Access, Filemaker Pro, and Oracle. (3) Lead efforts to improve database tools and other programs by coordinating and hosting meetings with database stakeholders. (4) Troubleshoot issues with the databases as needed. (5) Develop ad-hoc reports, queries and other deliverables within the databases. (6) Maintain accuracy of data files via multiple software systems, including computerized procurement reports and communication programs. REQUIREMENTS : The contractor must have: (1) Master’s degree in a related discipline; two (2) years of specialized experience plus a Bachelor’s degree is equivalent to a Master’s degree. (2) Minimum of two (2) years of related communications and/or project management experience. (3) Background in a scientific field; experience with communicating science or scientific policy. (4) Expertise with Microsoft Access (5) Skill in data analysis and presentation. (6) Ability to adapt and create tools to analyze and evaluate projects. (7) Strong communications skills, both oral and written. (8) Excellent analytical, organizational and time management skills. (9) Ability to anticipate staff needs in the varied avenues of research, analysis and reporting, and create alternative processes for addressing tasks where appropriate. PLEASE APPLY ONLINE Note that the phone number for our NIH branch is not listed. Due to the high volume of inquiries, we regret that we cannot accept phone calls. All qualified candidates will be contacted.


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Clinical Molecular Biologist

Date Posted:
3/10/2017

Kelly Government Solutions

MD

Clinical Molecular Biologist ** DNA Extraction, Sanger Sequencing, & CLIA Laboratory ** NIH ** Bethesda, MD Kelly Government Solutions is a strategic supplier and business partner to the federal government and its key suppliers. Through our partnership with the National Institutes of Health, Kelly Government Solutions offers administrative, IT, engineering, scientific, and healthcare professionals the opportunity to work with one of the most prestigious research organizations in the world. We are currently seeking a Clinical Molecular Biologist to work in a CLIA-certified clinical laboratory within the National Institutes of Health in Bethesda, MD. This is a long-term contract position which offers: - Competitive salary with comprehensive benefit package - Opportunity to work at NIH, world's foremost medical research center - Learn more about what Kelly can do for you at www.kellygovernmentsolutions.com TASKS/SERVICES : The contractor shall: Molecular Genetics Assays (1) Develop, validate and perform a variety of molecular assays in Clinical Laboratory Improvement Amendments (CLIA)-certified clinical laboratory to determine the DNA sequence changes that underlie inherited eye diseases; adhere to CLIA guidelines and mandates. (2) Interpret the results of DNA diagnostic assays; determine the significance for the patient’s health care management; provide written reports of assay results. (3) Develop and implement novel kits and technologies, including next generation sequencing, to aid in the analysis of microsatellite and other polymorphic loci in patient samples; implement liquid handling robotics to advance experimental efficiency. (4) Stay current with emerging genomics technologies and bioinformatics tools to assess the significance of DNA sequence variants. (5) Work with staff in the Ophthalmic Genetics and Visual Function Branch (OGVF) to apply standard molecular biological techniques to further experimentation including RT-PCR, molecular cloning, site-directed mutagenesis, primer design, Sanger sequencing, next-generation sequencing and all forms of nucleic acid purification. (6) Collaborate with other NEI laboratory staff, including members of the eyeGENE laboratory. (7) Prepare and present scientific and technical reports in peer-reviewed journals and at national/international conferences. Laboratory Management (1) Prepare Standard Operating Protocols (SOPs); maintain laboratory compliance and all appropriate paperwork in accordance with the regulations of the Clinical Laboratory Improvement Amendments (CLIA) of 1988. (2) Manage databases and repositories of patient samples; interact with physicians and investigators to ensure the proper sample tracking, processing and maintenance. (3) Maintain logs of all reagents and consumables in a CLIA-sanctioned manner. (4) Maintain temperature monitoring of freezers that house patient samples; respond to freezer failures 24 hours per day. (5) Maintain stocks of reagents and management of specialty equipment maintenance; interact with outside vendors. (6) Work with staff to train junior staff, collaborating investigators and summer interns in molecular genetics assays and the special requirements of clinical laboratories. Planning and Design of Research (1) Collaborate on the planning and design of research; analyze the results of ongoing laboratory experiments; assess and analyze pertinent research outside of NEI; collaborate on the future direction of laboratory experimental work. (2) Analyze data and results from current experiments; identify investigative outcomes relevant to research; assess the overall progress of the research and solicit input from other scientists; develop, design and recommend further experimental work and approaches to research. (3) Revise the specific experimental techniques or protocols to improve work methods or to accommodate revised experiment designs. (4) Participate in scientific staff assessments of research during laboratory meetings; exchange information and assessments with other scientists, collaborators from outside the laboratory and technical support staff. (5) Conduct literature searches; select and analyze data from pertinent literature; determine its applicability and relevance to the Section’s on-going research. (6) Maintain computerized files of laboratory protocols and data. REQUIREMENTS : The contractor ideally would have: (1) Ph.D. in a scientific discipline. Three (3) years of specialized experience plus a Master’s degree is equivalent to a Ph.D. Five (5) years of specialized experience plus a Bachelor’s degree is equivalent to a Ph.D. (2) Minimum of four (4) years of experience in a CLIA laboratory. (3) Hands-on experience in DNA sequencing. (4) Hands-on experience with DNA and RNA isolation from human blood, long range PCR, real-time quantitative PCR, gel electrophoresis, Sanger sequencing, STR analysis and other basic molecular biology. (5) Knowledge of bioinformatics tools and programs such as Sequencer, GeneMapper and online resources including those from NCBI, the UCSC genome browser and other specialty applications. (6) Extensive experience in next-generation sequencing technologies, database searching and record keeping. (7) License or certification for clinical laboratory. (8) Strong communications skills, both oral and written. (9) Excellent analytical, organizational and time management skills. PLEASE APPLY ONLINE Note that the phone number for our NIH branch is not listed. Due to the high volume of inquiries, we regret that we cannot accept phone calls. All qualified candidates will be contacted. Once you have applied online to the position, if you have specific questions, you may contact us at kellyrecruiter@mail.nih.gov


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Oncology Drug Discovery and Development Program Manager

Date Posted:
3/10/2017

Kelly Government Solutions

MD

Oncology Drug Discovery and Development Program Manager *** NIH *** Bethesda, MD ***Please Note Modified Job Title, Tasks, and Requirements*** Kelly Government Solutions is a strategic supplier and business partner to the federal government and its key suppliers. Through our partnership with the National Institutes of Health, Kelly Government Solutions offers administrative, IT, engineering, scientific, and healthcare professionals the opportunity to work with one of the most prestigious research organizations in the world. We are currently seeking an Oncology Drug Discovery and Development Program Manager to work with the National Institutes of Health in Bethesda, MD. This is a long-term contract position which offers: - Competitive salary with comprehensive benefit package - Opportunity to work at NIH, world's foremost medical research center - Learn more about what Kelly can do for you at www.kellygovernmentsolutions.com TASKS/SERVICES : The contractor shall: (1) Lead and manage drug discovery and development project teams. (2) Establish and maintain communication with Chemical Biology Consortium (CBC) Centers; oversee the NCI Experimental Therapeutics (NExT) Program pipeline, with an emphasis on cross-site CBC drug discovery projects. (3) Prepare documents and collect metrics on NExT pipeline for high level presentations to key stakeholders. (4) Facilitate project team discussions; identify gaps and inefficiencies to address seamless progression of projects in the NExT pipeline. (5) Contribute to a project team through intellectual, scientific engagement, and participation at team meetings. (6) Coordinate the external and NCI parties to establish agreements with CBC Centers and to make adjustments for changes in scope or scientific direction of projects in the pipeline. (7) Manage project team deliverables (e.g., reports, assay results, synthesized compounds of interest); ensure that all team members have access to scientific data. (8) Collaborate with staff on the preparation of project team reports and/or presentations; compile quarterly reports. (9) Interact with scientists as needed to help overcome technical hurdles or provide additional insights or expertise. (10) Interpret and evaluate scientific data, results and conclusions. REQUIREMENTS : The contractor ideally would have: (1) Ph.D. in a related discipline. (2) Minimum of ten (10) years of experience in the field of pharmaceutical and biotech business. (3) Minimum of five (5) years of experience working in a drug discovery project team environment, preferably in the pharmaceutical or biotech industry. (4) Demonstrated ability to interact constructively with other drug discovery scientists (biologists, chemists, pharmacologists, etc.) on a complex research project. (5) Comprehensive understanding of the small molecule drug discovery process, from assay development and screening through late-stage optimization and candidate selection. (6) Expertise in biochemical, cellular or animal pharmacology, with in-depth knowledge of protein biochemistry, enzymology, and structural biology, cancer target biology, molecular characterization of cell lines, and development of quantitative cellular assays, and/or pharmacokinetic analysis in rodents, selection and use of relevant efficacy for oncology, understanding of animal physiology and toxicology. (7) Demonstrated ability to rigorously interpret and evaluate scientific data, results and conclusions. (8) Recognized leadership skills and abilities in a project team setting, with the ability to manage teams or collaborations with participants based at different institutions and geographic locations. (9) An understanding of project management concepts and principles and experience working with them. (10) Recognized scientific standing demonstrated through a record of peer-reviewee publications. (11) Strong communications skills, both oral and written. (12) Excellent analytical, organizational and time management skills. PLEASE APPLY ONLINE Note that the phone number for our NIH branch is not listed. Due to the high volume of inquiries, we regret that we cannot accept phone calls. All qualified candidates will be contacted.


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Molecular Biologist

Date Posted:
3/10/2017

Kelly Government Solutions

MD

Kelly Government Solutions is a strategic supplier and business partner to the federal government and its key suppliers. Through our partnership with the National Institutes of Health, Kelly Government Solutions offers administrative, IT, engineering, scientific, and healthcare professionals the opportunity to work with one of the most prestigious research organizations in the world. We are currently seeking a Molecular Biologist to work with the National Institutes of Health in Baltimore, MD. This is a long-term contract position which offers: - Competitive salary with comprehensive benefit package - Opportunity to work at NIH, world's foremost medical research center - Learn more about what Kelly can do for you at www.kellygovernmentsolutions.com TASKS/SERVICES. The contractor shall: Investigate molecular and cellular mechanisms of immune cell aging in human (BLSA participants) and mouse model. Employ cutting edge genomic methods such as RNA-seq, ChIP-seq, microarray to identify genes and epigenetic changes that are altered expressed in old lymphocytes and monocytes, and confirm the alteration of expression by specific real time RT-PCR. Determine the size of TCR repertoire including both TCR alpha and beta genes, and their change with age in both CD4 and CD8 T cells and their subsets using the next generation sequencing technique. Analyze the telomere length changes in BLSA participants by Southern blot, quantitative PCR or qFISH . Process human blood samples; conduct routine primary immune cell culture in vitro . Perform immune cell phenotypic and functional analysis by flow cytometry; isolate specific lymphocyte subset from blood by magnetic isolation and cell sort. Genotype various genetically altered mouse strains and isolate immune cells from these mice for subsequent functional studies. Conduct proteomic analysis of selected proteins and its associated proteins. Design, initiate and conduct specific research projects described above. Participate in and present ongoing research and findings at weekly Lab and section meetings. Write and edit scientific papers. Present paper/abstract/poster at lab meeting and scientific meetings/conferences. Operate and maintain sophisticated and innovative instruments such as fluorescent microscope, flow cytometry, and next generation sequencing to perform tests, analyses and other laboratory procedures; perform routine laboratory maintenance. Schedule and maintain an accurate research tracking system and database for all research activities, daily records of experiments and results, including research documentation. Ensure that research stock supplies and reagents are kept stocked; obtain quotes for laboratory supplies, services and equipment needed to conduct research; prepare purchase requests for these items and submit to primary investigator and/or lab manager for approval. REQUIREMENTS OR OTHER EXPERTISE REQUIRED. The contractor must have: Ph.D. in Biology, Life Sciences or a related discipline. Minimum of five (5) years of experience in biology or a related field. Strong background in genetics, molecular biology or a related discipline. Familiarity with age associated changes in immune system. Ability to work independently and think critically with skilled hands and sound judgment. Experience in genetics, molecular biology and the recent new advanced methods. Knowledge of proper laboratory disposal methods and safety procedures. PLEASE APPLY ONLINE Please visit www.kellycareernetwork.com to apply for this position. Due to the volume of inquiries, we regret that we cannot accept phone calls. Please also note that the phone number for our NIH branch is not listed.


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Mental Health Communications Editor

Date Posted:
3/10/2017

Kelly Government Solutions

MD

Mental Health Communications Editor/Coordinator ** NIH ** Rockville, MD ***Seeking candidates with neuroscience, psychology, and/or mental health background and experience to translate scientific and technical content into plain language for a variety of audiences. Please note this position requires hands-on experience with all aspects of science writing, editing, communications planning, and coordination*** Kelly Government Solutions is a strategic supplier and business partner to the federal government and its key suppliers. Through our partnership with the National Institutes of Health, Kelly Government Solutions offers administrative, IT, engineering, scientific, and healthcare professionals the opportunity to work with one of the most prestigious research organizations in the world. We are currently seeking a Mental Health Communications Editor/Coordinator to work with the National Institutes of Health in Rockville, MD. This is a long-term contract position which offers: - Competitive salary with comprehensive benefit package - Opportunity to work at NIH, world's foremost medical research center - Learn more about what Kelly can do for you at www.kellygovernmentsolutions.com TASKS/SERVICES: The contractor shall: (1) Develop strategic plans for science communications using state-of-the-art digital and traditional channels, including media, social media, web, video, mobile applications, online networks and other emerging platforms; develop plans to define clear goals, messages, target audiences, dissemination methods and metrics for monitoring implementation and/or impact. (2) Work with project teams and ensure that all communications activities outlined in strategic plans are tracked, coordinated and implemented, and that milestones are met and goals are achieved per established timelines. (3) Research and develop a variety of materials as background information to be used in preparing written and oral communication documents and presentations for the Institute Director and staff. (4) Work with Senior Content Strategist to define, implement and coordinate the overall NIMH enterprise content presentation strategy across all print and digital channels. (5) Oversee and manage web content, including accuracy and relevancy of posted scientific content and new web updates as directed; periodically review web site and make recommendations for improved user experience and information architecture. (6) Research, fact-check, edit, author and disseminate statements, press releases, reports, articles, speeches, presentations, and other materials about complex scientific information. (7) Provide support for media relations operations, including conducting background research on journalists, pitching reporters, writing talking points, clearing interview requests, gathering background materials, attending interviews, and analyzing coverage. (8) Serve as NIMH liaison to the Mental Health.gov editorial board by attending regularly scheduled meetings; provide guidance on content; draft and edit blogs for the site. (9) Develop the agendas, take minutes and track goals and action items for the Behavioral Health Coordinating Committee (BHCC) Communications Subcommittee and other ad hoc workgroups. (10) Design, produce, and evaluate information materials to reach national and international audiences through the media and intermediaries such as advocacy and professional organizations; disseminate this material to relevant audiences as directed. (11) Prepare major reports and documents for publication from development through concept clearance; edit and rewrite material prior to publication; coordinate with layout and graphic design team to ensure efficient and effective presentation. (12) Participate in the implementation, maintenance, enhancement and coordination of online systems and websites. (13) Oversee the identification and production of informational materials for NIMH website(s) and monitor the site(s) to ensure that posted information is accurate, timely and vetted according to required clearance procedures. (14) Work to establish and maintain contacts and working relationships with persons in professional and advocacy organizations, private industry and voluntary agencies to facilitate the nationwide dissemination of information and to gather information needed for the development of information materials and programs. (15) Build relationships with communications professionals, scientific staff, and program leaders across HHS, NIH Institutes and Centers, and other organizations to facilitate partnerships, information sharing and goal attainment. REQUIREMENTS: The contractor must have: (1) Ph. D. in Psychology, Neuroscience or a related discipline; three (3) years of specialized experience plus a Master’s degree is equivalent to a Ph.D. (2) Minimum of three (3) years of related experience, including federal government communications. (3) Experience in health communications, outreach and coordination. (4) Experience in project management. (5) Experience in developing strategic communications plans and communications program evaluation. (6) Experience writing and copy editing scientific content in plain language for a variety of audiences. (7) Extensive knowledge of web and social media platforms. (8) Experience in media relations, either as a public relations professional or a journalist. (9) Experience using multiple software programs, platforms and tools, including Microsoft Office Suite (MS Word, Excel, Outlook), Adobe, Acrobat Pro, SharePoint and GoToMeeting. (10) Strong communications skills, both oral and written. (11) Excellent analytical, organizational, and time management skills. PLEASE APPLY ONLINE Note that the phone number for our NIH branch is not listed. Due to the high volume of inquiries, we regret that we cannot accept phone calls. All qualified candidates will be contacted. Once you have applied online to the position, if you have specific questions, you may contact us at kellyrecruiter@mail.nih.gov


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Lecturer Biology

Date Posted:
3/10/2017

Oxfrod College

GA

Emory University's Oxford College seeks candidates for a Lecturer in Biology to begin August, 2017. The successful applicant will teach one lecture with laboratory course per semester in introductory biology and/or environmental science for majors and non-majors. The professional responsibilities are half teaching and half laboratory preparation for cell biology, genetics, and organismal biology.
REQUIRED: A minimum of a Masters degree in a biology sub-discipline with broad training in biology is required, along with at least one year of laboratory teaching experience in general biology.


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Scientific Annotator

Date Posted:
3/10/2017

MindSpec

VA

Position Description:
We are seeking talented and motivated individuals interested in working in a multi-disciplinary team. The positions offer an opportunity to work in the rapidly evolving area of multi-factorial disease biology in a flexible, dynamic research environment.
MindSpec, Inc. (http://www.mindspec.org/), is a nonprofit research organization that studies molecular causes of neurodevelopmental disorders such as autism using an integrated bioinformatics approach. MindSpec created the first genetic database for autism (AutDB), which is licensed to the Simons Foundation as SFARI Gene (https://gene.sfari.org/).

Qualifications:
Applicants must have an M.S. degree or higher in Genetics/Molecular Biology/Neurobiology or a related field with a strong knowledge of animal models of human disease. Applicants should also have excellent written and oral communication skills. Candidates who have research experience with zebrafish (Danio rerio) or Drosophila melanogaster are encouraged to apply.

Responsibilities:

Assess peer-reviewed scientific publications to determine their suitability in the context of given inclusion criteria.
Read and extract data from peer-reviewed scientific publications.
Use, evaluate and provide direction to develop data models and standards.
Take part in weekly meetings to help promote interpretative consistency between team members.
To Apply:
Please send cover letter and curriculum vitae to job@mindspec.org.


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Postdoc Neuromodulation

Date Posted:
3/10/2017

FDA

MD

Post-doctoral Fellow with FDA –Neuromodulation Job description A postdoctoral fellowship is available at Food and Drug Administration (FDA), Center for Devices and Radiological Health (CDRH), Office of Science and Engineering Laboratories (OSEL), Division of Biomedical Physics (DBP). The position is located at FDA White Oak main campus in Silver Spring, MD. Program participants will be paid a monthly stipend that is dependent on experience (starting from $79,720 per year). Funding is currently available for 1 year with the possibility of extension. The candidate must have received her/his most recent degree within 5 years prior to starting. The applicant has to be eligible to work in the U.S. Project description Neuromodulation is a growing field of therapy for its direct and focal effects on the neuronal circuits, which has the potential to be expanded for enhancing learning capabilities. However, the safety and efficacy of neuromodulation in healthy individuals and the potential sex differences needs further investigation. This project is aimed at understanding the safety and efficacy of neuromodulation using the in rodents, along with understanding of the potential sex difference. The outcome of this research would help answer some of the engineering and biological questions associated with neuromodulation and will help shape a modern regulatory landscape. Role of candidate The candidate will be involved in lab studies for evaluating neuromodulation in the autonomic nervous system. The role requires the candidate to perform rodent surgeries, electrical neural stimulation, electrophysiology, functional assays and immunohistochemistry. Activities may include experimental design, developing custom hardware and software setup, MATLAB scripts for data analysis and animal handling. The qualified candidate should have a Ph.D. in Biomedical Engineering, Neuroscience, Electrical Engineering or a related field. Preference will be given to applicants with some or all of the following skills and experience: • Engineering and scientific curiosity • Problem solving skills • Knowledge of neuroscience • Knowledge of endocrinology • Knowledge of immunology • Peripheral nerve surgery • Experience with telemetry implantation, data acquisition and analysis • Laboratory experience with animal handling and surgery • Electrophysiology - recording, stimulation and data analysis • Immunohistochemistry/Histology • Proficiency in MATLAB, Python, or at least one programming language The following knowledge/expertise is desired: • Experience with neuromodulation • Effective oral and written communication skills as demonstrated by presentation in international conferences and publications in peer reviewed journals How to apply To apply, please email Srikanth.Vasudevan@fda.hhs.gov including CV/resume with a cover letter in the body of the email and “Post-doctoral Fellow – Neuromodulation” in the subject line. The position is available immediately. Note that this appointment is offered through the CDRH Postgraduate Research Participation Program and is administered by the Oak Ridge Institute for Science and Education (ORISE). The program is open to all qualified U.S. and non-U.S citizens without regard to race, color, age religion, sex, national origin, physical or mental disability, or status as a Vietnam-era veteran or disabled veteran. The individual selected for appointments will not become employees of ORISE, ORAU, DOE, FDA, CDRH, or any other office or agency. Proof of health insurance is required for participation in this program. The appointment is full-time at FDA in the Silver Spring, MD. Company description The Food and Drug Administration (FDA) is an agency within the U.S. Department of Health and Human Services. FDA is responsible for protecting the public health by assuring the safety, efficacy and security of human and veterinary drugs, biological products, medical devices, our nation’s food supply, cosmetics, and products that emit radiation. This position is within the Center for Devices and Radiological Health (CDRH). CDRH seeks to assure that patients and providers have timely and continued access to safe, effective, and high-quality medical devices. CDRH facilitates medical device innovation by advancing regulatory science, providing industry with predictable, consistent, transparent, and efficient regulatory pathways, and assuring consumer confidence in devices marketed in the U.S. The Office of Science and Engineering Laboratories (OSEL) is the research arm of the Center for Devices and Radiological Health (CDRH). OSEL performs product testing; develops reliable standardized test methods for CDRH and industry use; performs anticipatory scientific investigations on emerging technologies; contributes laboratory data to national and international standards used in CDRH decision making; provides scientific and technical training for CDRH staff members; and maintains laboratory collaborations and relationships with scientific researchers in academia and other Federal laboratories. OSEL also coordinates and oversees CDRH’s activities that support the development of national and international standards.


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Patent Analyst Life Sciences

Date Posted:
3/9/2017

CPA Global

VA

Job description

Join the team! CPA Global seeks excited, inquisitive, and collegial individuals to join its Patent Search and Innovation Intelligence Services Team. Patent Analyst opportunities are available within two Patent Search divisions: the Patent Cooperation Treaty (PCT) and also the Commercial Search Group located in either Alexandria, VA or Southfield, MI offices. Remote employment is available in some circumstances.

 

 

 

For more information, see job descriptions below.

 

CPA Global is the world’s leading IP management and information Services Company with the insight, experience, and global expertise to create, protect, maintain, and maximize IP assets on a global scale.

 

As a business, CPA Global unlocks fresh thinking and inception of technology initiatives for clients throughout the world. Its teams of professionals synergize ideas and action, connect people with people and people with technology to ensure that individuals and organizations fulfil their potential.

 

CPA Global is a trusted business partner. It combines an entrepreneurial spirit with a “customers first” approach. The company works with honesty, integrity, and professionalism. CPA Global is responsive and responsible. These are qualities its clientele values and the company seeks to uphold.

 

CPA Global provides a casual and relaxed work environment focused on continuously exceeding its customers’ expectations. A hands-on training program focuses on developing knowledge and skills while allowing new employees to immediately produce results.

 

 

JOB DESCRIPTION

 

PCT Patent Analyst (Full Time)

  1. Assess the technology and disclosure to understand the technical nuances in preparation for performing the search to identify relevant references and documents.
  2. Maintain proficiency with commercial patent databases and other proprietary databases that disclose technical publications.
  3. Strategically perform searches and draft written opinions relating to patentability of PCT applications in the Analyst’s broad technical area.

 

 

 

 

 

 

Commercial Search Group (Full Time)

  1. Strategically perform searches relating to patentability (novelty), validity, freedom-to-operate and infringement in the computer science technical area.
  2. Perform Evidence-Of-Use studies by analyzing products currently used in the market that may be infringing on a patent of interest.
  3. Perform qualitative analysis of patents and patent portfolios from a legal, technical and business perspective.
  4. Conduct long-term patent landscape studies to identify trends in a technology field, deliver competitive intelligence and identify potential research and licensing opportunities.
  5. Maintain proficiency with commercial patent databases and other proprietary databases that disclose technical publications.
  6. Communicate effectively with customers in determining the scope of searches and draft informative reports that clarify and summarize search results.

 

 

 

 

REQUIREMENTS

 

Work Experience or Education required in one of the following areas:

 

  • Biotechnology (or Biology) – Cell and molecular biology, microbiology, human physiology, biochemistry, biophysics, stem cells, genetic engineering, pharmacology, biofuels, antibodies and immunology, vaccines, etc.

  • Life Sciences – Surgical equipment and procedures, medical devices, medical instrumentation, diagnostic equipment, medical imaging equipment, implantable devices, prosthesis, etc.

 

QUALIFICATIONS

 

 

  • (PCT Full Time Requirement ONLY) U.S. citizens or work eligible legal residents who have resided in the U.S. for at least the two previous years.
  • Bachelor’s Degree
  • 0-3 years previous patent examining or patent searching experience is strongly preferred, though not required.
  • In-depth knowledge of technical literature in the area of subject matter expertise.
  • Extreme attention to detail required.
  • Highly skilled developing a search methodology and in conducting searches.
  • Strong time management skills and dependable in completing quality projects against deadlines.
  • Excellent interpersonal, oral and written communication skills.

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Senior Field Applications Specialist Genomics 4 positions different locations

Date Posted:
3/9/2017

Covance

NC

Job description

Senior Field Applications Specialist Genomics

 

The Senior Field Applicantion Specialist is an expert in the the clinical application of Genomics and Biomarkers. The Field Application Specialist for Genomics supports clients in East Coast Mid-Atlantic territory and provides scientific expertise and guidance to Pharma and Biotech Clients and Business Development Directors during all stages of the sales process, with specific focus on the technical aspects of project planning and RFP support.

 

Key Job Duties Include

 

  • Works with Business Development Directors to ensure appropriate technical genomics strategy/solution is proposed to client. Monitor actions and results against client expectations.
  • Works directly with Operations, R&D, and Bioinformatics to maintain an advanced technical and operational understanding of Covance Drug Development service offerings
  • Actively prospect and leverage potential new business opportunities.
  • Work with management to identify target clients, markets and services that matches the company's capabilities.
  • Work across company's service lines and with sales teams to cross-promote and respond to RFPs as well as develop internal relationships needed to create solutions designed using multiple services.
  • Support sales and marketing services by attending, participating and speaking at trade shows and industry conferences.

     

Education/Qualifications - Bachelor's Degree Required.

 

  • Ph.D. or Master's degree in a scientific discipline (Molecular/Cellular Biology, Genomics) preferred.
  • Understanding of business and Industry trends and ability to interpret the trends relevant to the business.
  • Excellent analytical skills in assessing and interpreting customer technical requirements.
  • Excellent communication skills (written and verbal).
  • Ability to create and give technical oral presentations to large groups of scientists.
  • Must be self-directed and capable of prioritizing opportunities and performing multiple tasks.

     

Experience Experience

 

  • 7 years Experience and working knowledge of the principles of Translational Sciences, Genomics and Biomarkers with focus on Experience in clinical applications of the above sciences.

     

EEO Employer Covance is committed to diversity in the workplace and is an equal opportunity employer (Minority/Female/Individual with Disability/Veteran/Sexual Orientation/Gender Identity). Your confidentiality and privacy are important to us.

 

Raleigh-Durham, NC

 

Raleigh-Durham, North Carolina

Seniority Level

Entry level

Industry

  • Biotechnology
  • Hospital & Health Care
  • Pharmaceuticals

Employment Type

Full-time

Job Functions

  • Research
  • Analyst
  • Information Technology

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Scientist/Senior Scientist

Date Posted:
3/9/2017

Cellular Dynamics International

WI

Company Description

We develop and manufacture fully functioning human cells in industrial quantities to precise specifications. Our proprietary iCell Operating System (iCell O/S) includes true human cells in multiple cell types (iCell products), human induced pluripotent stem cells (iPSCs) and custom iPSCs and iCell products (MyCell products).

Our iCell O/S products provide standardized, easy-to-use, cost-effective access to the human cell, the smallest fully functioning operating unit of human biology. Customers use our iCell O/S products, among other purposes, for drug discovery and screening; to test the safety and efficacy of their small molecule and biologic drug candidates; for stem cell banking; and in researching cellular therapeutics.

Job Description

Cellular Dynamics, a FujiFilm Company, is currently hiring for a Scientist/Senior Scientist position at our Madison, WI location. This position requires a self-motivated individual with demonstrated proficiency in mammalian cell culture and stem cell biology (cell culture and differentiation) who can contribute to our efforts to efficiently manufacture differentiated human cell types from human induced pluripotent stem cells.

Qualifications

Qualifications

Skills and Responsibilities:

• Mammalian cell culture including human induced pluripotent stem cells and differentiated cells.
• Differentiation of stem cells into multiple differentiated cell lineages.
• Cell culture medium production and optimization.
• Quantitative biochemical, cell, and molecular biology analyses, such as gene and protein expression, immunohistochemistry and flow cytometry,
• Functional assessment of differentiated cell function using cell specific assays.
• Design, planning and efficient execution of experiments that meet scientific goals and timelines.
• Effective written and oral communication of experimental design, rationale, and results to peers and management.
• Good documentation practices when documenting ideas, recording data, and completing records.
• Effective drafting of standard operating procedures.

Essential Job Requirements:
• Relevant experience or an advanced degree (M.S. or Ph.D.) in stem cell biology, cell biology, developmental biology, biomedical engineering or a closely related field.
• Proficiency in pluripotent stem cell culture and differentiation of pluripotent stem cells is required.
• Knowledge of general developmental biology and bioinformatics principles is desirable.
• Possess initiative, ability to multi-task and a desire to acquire new technical skills.
• Proficiency in independent experimental design, planning and execution.
• Experience operating in a team-based multidisciplinary environment is desirable.
• Excellent record keeping and organizational skills.
• Excellent oral and written communications skills.
• Flexible work schedule, weekend work is required.
• Proficient use of software such as MS Office, Prism and various flow cytometry programs.
• Project planning and experience operating in a team-based multidisciplinary environment is desirable.
• Industry and personnel management experience is desirable

Additional Information

Cellular Dynamics International Inc. is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, age, protected veteran status or status as an individual with a disability. All qualified applicants will not be discriminated against on the basis of a disability.


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Field Application Scientist

Date Posted:
3/9/2017

Cellular Dynamics International

MA


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Field Application Scientist

Date Posted:
3/9/2017

Quanterix

MA

Job description

Quanterix is an exciting early-stage commercial company currently developing a transformational platform that combines proprietary single-molecule sensitivity, multiplexing and full automation with its revolutionary Single Molecule Array (Simoa) technology. Located in Lexington, MA, the company has launched an instrument for the life sciences research industry. With unprecedented sensitivity, precision, multiplex capabilities, and full automation, Simoa offers significant benefits for both research and clinical testing applications. Quanterix is looking to hire an experienced Field Applications Scientist currently located in the Boston area to support the market development of its Simoa HD-1 Analyzer.

 

This critical role, first and foremost, will work very closely with the Quanterix Account Managers to support the sales process where greater technical depth is required, such as presentations at customer sites and at conferences. This person is also responsible for ensuring that customers are successful once they start using Simoa through effective training and support. The Field Applications Scientist will work closely with and support the Field Service organization to help customers quickly resolve any technical or operational issues. Finally, this individual is expected to work closely with the internal Assay Development and R&D teams to help develop new customer-driven applications.

 

Qualifications/Requirements

 

    • Masters Degree or higher in biology, chemistry, biochemistry or related field, a PhD. is preferred
    • 5+ years of customer-facing experience in applications, technical sales support, or related functions
    • Strong understanding of, and experience with, current immunoassay platforms and technology
    • Experience supporting novel, ground-breaking technologies preferable
    • Equally comfortable in front of customer as in the lab
    • Excellent technical communication and writing skills
    • Proficiency in spoken and written English
    • Team spirit, positive attitude, strong work ethic.

 

About Quanterix

 

Quanterix Corporation is a privately held, dynamic and growing company located in Lexington, Massachusetts. We are building a team of best-in-class scientists, engineers and business professionals that thrive in a collaborative high-energy entrepreneurial environment. We believe that the commercialization of an enabling technology with the potential to revolutionize life science research and clinical diagnostics will require the very best people working together and exchanging ideas while sharing a commitment to innovation. Quanterix is an Equal Opportunity Employer that offers a competitive and comprehensive employee benefits package, including health, dental, life insurance, a flexible spending plan, paid vacation, stock options and a 401(k) investment plan.

Seniority Level

Associate

Industry

  • Biotechnology

Employment Type

Full-time

Job Functions

  • Research
  • Analyst
  • Information Technology

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Field Application Scientist

Date Posted:
3/9/2017

Nanostring

CA

Job Summary

 

The Field Application Scientist works with the Regional Account Managers to ensure customer adoption, success, acceptance, and driving additional revenue growth with the technologies offered by NanoString Technologies.

 

Territory: Los Angeles, California and a variety of Mountain and South Western States

 

Essential Functions

 

    • In partnership with the Regional Account Managers (RAMs), identify sales opportunities through identification and relationship building with P.I.s in positioning the power and utility of NanoString's technologies for their research or developmental efforts
    • In pre-sales environments, conduct seminars, give technical sales presentations, and collaborate with P.I.s in the building and designing of projects to either support the purchasing of an nCounter system or through partnership with an institutional/regional core lab (if available)
    • In post-sales environments, train new customers on the system, partner with clients in project scoping and design elements to increase CodeSet adoption and usage, conduct data analysis sessions with regional customers to accelerate full adoption of the technology, provide on-site troubleshooting as needed, and participate in the cultivation of revenue generating post-sales support and consultative opportunities
    • Partner closely with the Regional Account Managers in the positioning of new technologies as they are released. Develop partnerships that may contribute to early access programs for these technologies
    • Collaborate with the in-house Technical Services team and other Field Applications Scientists in the post-sales support of customers and their applications
    • Contribute to the development and refinement of the processes and materials used by the global support teams in the information and tools needed by the global team in advancing the needs of our customers
    • Be trained on NanoString's Diagnostic product lines to provide triage support as well as implementation support in the Western U.S. (approx. 10%)

 

Requirements

 

  • Requires a Ph.D. in a molecular biology / biochemistry related field
  • At least 3 years of relevant practical laboratory experience and technical expertise
  • Focused research/academic experience in Immunology and/or Immuno-oncology highly preferred
  • Experience and/or deep understanding of the following areas highly preferred: Gene Expression analysis, miRNA, Copy Number Variation, IHC, Flow Cytometry, RNASeq, QPCR, and Protein Expression assays
  • Experience with biostatistics and computational data analysis is strongly preferred
  • Requires excellent communication skills, verbal and written
  • Ability to travel up to 75%
  • Experience in a technical customer support role desirable
  • Commercial experience desirable
  • Strong working knowledge of the sales process as well as a good understanding of the Miller Heiman selling process and terminology preferred but not required

Job posted by

Maya Skolnik

Recruiting & Talent Manager at NanoString Technologies, Inc.

Job Poster Location

Greater Seattle Area

Premium

Seniority Level

Not Applicable

Industry

  • Biotechnology
  • Research
  • Medical Devices

Employment Type

Full-time

Job Functions

  • Research
  • Analyst
  • Information Technology

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Field Application Scientist

Date Posted:
3/9/2017

MSD

PA

Job description

Field Application Scientist II

 

POSITION SUMMARY:

 

Provide comprehensive scientific consultation to support account management in tandem with the internal sales organization. Consult is provided in a highly personalized and customized client-centric approach at the individual customer site or remotely through phone and e-mail communications. The incumbent should demonstrate a strong desire to succeed in a competitive commercial environment and will carry out evaluations at prospect sites for new instrument opportunities, support new and existing customers in the use of MSD kitted assays and in the development of new assays in a multidisciplinary setting.

 

This position may mentor junior level staff and manage more complex operations and/or larger territory and strategic accounts than Field Application Scientist. The incumbent should be based in Philadelphia.

 

DUTIES AND RESPONSIBILITIES:

 

  • Educate, train and support new/existing customers on MSD instrumentation and data analysis.

 

  • Train customers on the use of MSD assays, instrumentation and software
  • Assist existing customers with assay troubleshooting and data analysis
  • Provide support for customers wishing to develop their own assays on the MSD platform
  • May include but not be limited to inflammation, oncology, metabolic disorders, neuroscience, immunogenicity, PK, toxicology, bioproduction
  • Effective and timely response time to inquiries
  • Attend scientific meetings, conferences and trade shows, provide feedback and reports
  • Travel 30 to 50% of the time; able to work at customer sites four days a week
  • Work as part of a team and integrate information between sales and marketing groups to provide resolution of customer issues and expand the customer base through scientific networking.

 

  • Integrate with account managers in the strategic selling process to grow instrument and consumable sales in the territory.
  • Present scientific seminars to prospects
  • Create reports and presentations from assay development visits and new evaluations
  • Provide feedback from the field to other team members, account managers and internal groups
  • Document activities and customer interactions in the CRM software (SalesForce.com)
  • Specific duties may vary depending upon departmental requirements.

 

EXPERIENCE AND QUALIFICATIONS:

  • Ph.D. in Life Sciences or related area required
    • Master’s degree in related field with equivalent experience considered
  • At least 7-10 years of experience in a field application or scientific support position required
  • 3-5 years of hands on experience working in molecular biology lab, clinical lab, discovery lab or biochemistry in a research or clinical setting is required
  • Experience in protein biochemistry required
  • Experience with immunoassays required
  • May supervise others’ work and/or mentor other Field Application Scientists

 

 

 

KNOWLEDGE, SKILLS AND ABILITIES:

  • Demonstrate superior competency in analytical skills and strong scientific fundamentals
    • Logical problem solving and demonstrated ability to organize and move project tasks forward in an orderly and structured fashion
  • Display a thorough understanding of the principles of immunoassays, their development and their applicability in different research fields
    • Independently execute assay and reagent troubleshooting, optimization and validation experiments
  • Excellent oral, written communication and interpersonal skills as a core competency to include presentation and training styles
    • Effectively communicate issues/problems and results that impact timelines, accuracy and reliability of laboratory data
  • Demonstrate effective time and project management and competency in a customer-centric environment
  • A wide degree of creativity and latitude is expected including the ability to multi-task and work productively in a demanding research environment with changing priorities

 

 

 

PHYSICAL DEMANDS:

This position requires the ability to communicate and exchange information, utilize equipment necessary to perform the job, and move about the office and travel on a regular basis.

 

 

 

WORK ENVIRONMENT:

This position may require up to 30-50% travel within the designated territory, being present at customer sites up to four/five days a week. Candidates should also expect to spend time in a laboratory environment occasionally working with blood products and various allergens


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Expert Scientist Molecular Analystics

Date Posted:
3/9/2017

GSK

MD

Basic Qualifications

 

  • MSc plus at least 10 years of experience in an industrial, academic, or government laboratory setting

     

Preferred Qualifications

 

  • PhD plus 3 years of experience in an industrial, academic, or government laboratory setting
  • Excellent Publication Records

     

Details

 

Job Purpose:

 

Key member with expertise in Next Generation Sequencing (NGS) and bioinformatics related to the area of infectious disease research, in diverse team of vaccine scientists, to design, characterize, optimize, evaluate and select vaccine candidates, and support platform technology development.

 

Key Responsibilities

 

  • Demonstrates a detailed fundamental knowledge in NGS and bioinformatics, as they apply to vaccine discovery and development
  • Have practical knowledge of multiple NGS platforms, e.g. Illumina, Pac Bio, and the analysis of NGS data sets, particularly related to infectious agents
  • Subject matter expert in most relevant fields involving the team
  • Has transversal overview of all related activities within the department
  • Leads vaccine development-related scientific investigations, and publishes the work in scientific journals and patent filings
  • Executes a wide range of experiments/technical studies/tasks independently based on protocol
  • Develop and executes new methods and protocols and proactively incorporates new technology or techniques into practice with minimal supervision
  • Performs complex data management tasks with minimal supervision
  • Interprets results and communicates to the supervisor and designs next logical step of experiments based on interpretation of results
  • Prepares oral or written summaries of results with interpretation for projects/programs
  • Independently writes specific technical sections of internal, external reports, and scientific papers

     

Contact Information

 

You may apply for this position online by selecting the Apply now button.

 

If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK HR Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).GSK is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.

 

Important notice to Employment businesses/ Agencies

 

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

 

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit GSK’s Transparency Reporting For the Record site.


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Bioinformaticist Scientist, Cancer

Date Posted:
3/9/2017

Qiagen

NC

QIAGEN/Omicsoft is seeking a highly motivated and experienced bioinformatics scientist who can contribute his/her own unique perspectives to our collective understanding of genomics data for biomedical researches. The primary responsibility is to understand genomics data from varied disease areas, and to develop data analysis plans/pipelines to generate biological meaningful results and visualizations. By collaboratively working with internal research and development team, the successful candidate will integrate acquired knowledge into our efforts to provide great genomics knowledge products to our clients.

 

 

 

Job location: Cary, NC or Redwood City, CA

 

 

 

Key Responsibilities

  • Collaborate with colleagues to understand our clients’ interests and biological questions
  • Develop data analysis strategies and plans to address clients’ need.
  • Perform data analysis on genomics data sets using Omicsoft products as well as other Bioinformatics and statistical tools
  • Prepare presentations to summarize findings and train customers
  • Training customers to explore data and answer biological questions using Omicsoft software and Lands
  • Other data analysis and bioinformatics researches funded by clients

 

 

 

Basic Qualification

  • PhD in Bioinformatics, Computational Biology or related fields
  • Research experience in the fields of genomics and NGS data analysis
  • Understanding of basic biology and cancer biology
  • Experience with R, Python or Java, Unix/Linux/HPC
  • Enjoys working in collaborative team environment
  • Strong written and oral communication skills to present scientific data and methods

 

 

 

Preferred Qualifications

  • Experience in cancer research and drug development is a plus

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Prinicple Scientist Protein

Date Posted:
3/9/2017

Alkermes

MA

Alkermes plc is a fully integrated, global biopharmaceutical company developing innovative medicines for the treatment of central nervous system (CNS) diseases. The company has a diversified commercial product portfolio and a substantial clinical pipeline of product candidates for chronic diseases that include schizophrenia, depression, addiction and multiple sclerosis. Headquartered in Dublin, Ireland, Alkermes plc has an R&D center in Waltham, Massachusetts; a research and manufacturing facility in Athlone, Ireland; and a manufacturing facility in Wilmington, Ohio. For more information, please visit Alkermes’ website at www.alkermes.com .

 

Position Description: Alkermes is searching for a highly talented scientist for a position primarily responsible for designing our next generation of protein therapeutics. The ideal candidate will take a leading role in ideation and engineering of new proprietary fusion proteins, additionally executing and guiding in vitro studies through proof-of-principle.

 

Key Duties

 

    • Primary responsibilities for designing our next generation of protein therapeutics, including but not limited to expression, purification, biophysical characterization and cell-based activity assays

       

    • Prosecute novel therapeutic proteins to demonstrate proof-of-principle using in-house capabilities as well as external resources (CROs)

       

    • Participate in advancing Alkermes pipeline and capabilities in protein therapeutics

       

    • Support IP protection and publications

       

 

Technical Skills

 

    • Protein design and engineering

       

    • In-depth understanding of protein structure-function, with knowledge in modeling

       

    • Bacterial and mammalian protein expression (including transient transfection)

       

    • Protein purification (experience with AKTA FPLC purification systems required, HPLC/UPLC a strong plus)

       

    • Protein characterization techniques, including chromatography, label-free technologies (e.g. Biacore or Octet), and mass spectrometry

       

    • Other analytical techniques including SDS-PAGE, flow cytometry and immunoassays (ELISA and/or MSD) analysis

       

    • Experience in standard molecular and cell biology techniques (bacterial and mammalian cell culture)

       

    • Assay development and execution (in vitro, cell-based, ex vivo) with expertise in multiple assay formats (e.g. fluorescence, luminescence, FRET, FP, high content imaging)

       

    • Highly effective written and verbal communication skills

       

 

Personal Skills

 

    • Ability to rapidly identify, learn and apply techniques

       

    • Ability to independently drive projects

       

    • Ability to multi-task, and independently design, execute experiments

       

    • Sense of urgency (self-motivation)

       

    • Scientific creativity

       

    • Flexibility to learn and take on new tasks according to changes in priority

       

    • Strong interdisciplinary communication skills

       

 

Minimum Education And Experience

 

    • PhD in a relevant scientific discipline (cell biology, biochemistry, biophysics or related discipline) with > 5 years experience in the biotechnology/pharmaceutical industry setting required

       

 

Alkermes, Inc. is an equal employment opportunity employer and does not discriminate against any applicant because of race, color, religion, sex, sexual orientation, gender expression and identity , national origin, ancestry, age, mental and physical disability, genetic information, any veteran status, military status or application for military service, or membership in any other category protected under applicable law.


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Postdoctoral Fellow Computational Microbiologist

Date Posted:
3/9/2017

Henry M Jackson Foundation

MD

The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HJF) is seeking a Postdoctoral Fellow II to support the Enteric Diseases Group in the Department of Preventative Medicine and Biostatistics at the Uniformed Services University (USU) in Bethesda, Maryland. HJF provides scientific, technical and programmatic support services to USU. Responsible for initiating and carrying out research projects in collaboration with Drs. David Tribble and Mark Riddle.

 

 

 

 

Responsibilities:

1. Assists in designing, developing, executing, and implementing scientific research and/or development.

2. Investigates the feasibility of applying a wide variety of scientific principles and theories to potential inventions and products.

3. Uses appropriate software packages to analyze whole genome sequencing, functional gene array, and proteome array data from high throughput technologies.

4. Collects and handles data and keeps detailed records of experiments.

5. Assists with the preparation of data for presentations at scientific meetings and for publication in journals.

6. Assists with training staff as needed.

7. Performs other duties as assigned.

 

 

 

Required Knowledge, Skills, and Abilities: Knowledge of biological network analysis; Proficiency in R, BioPerl, UNIX, and other related languages; Understanding of host:pathogen interactions

 

 

 

Minimum Education/Training Requirements: PhD in computational biology, biostatistics, computational science, microbiology, or related field

 

 

 

Minimum Experience: 2-4 years

 

 

 

Physical Capabilities: Long periods of sitting; intricate work with hands

 

 

 

Supervisory Responsibilities/Controls: Provide guidance to laboratory staff

 

 

 

Work Environment: Office environment; may require working evenings and weekends

 

 

 

HJF is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or protected veteran status.


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Postdoc Fellow

Date Posted:
3/9/2017

Geneva Foundation

MA

Overview:

 

 

 

 

 

The Postdoctoral Fellow I provides assistance to the Principal Investigator, Co-Investigators, and Research Staff. S/he ensures protocol adherence, monitoring visits, overseeing regulatory and administrative details, data management assistance and project close-out support is provided.

 

US Citizenship Required

 

 

 

Responsibilities:

 

 

 

 

 

  • Collaborate and assist the Principle Investigator, Co-Investigators and research team in the performance the research study
  • Contribute to the drafting and submitting of abstracts, manuscripts and reports for dissemination
  • Prepare progress reports on research as required
  • Analyze and write-up data
  • Present complex information effectively to a range of audiences
  • Provide data management assistance
  • Provide project close-out support
  • Maintain and promote Geneva’s core values of Integrity, Superior Service to Customers, Quality, Teamwork, Innovation, and Respect for All
  • Possess a working knowledge of The Geneva Foundation’s Employee Handbook, User’s Guide and Standard Operating Procedures (SOPs) as applicable
  • Remain accessible and accountable at all times during work hours and collects messages at least twice daily
  • Return telephone messages within 24 hours of receipt; return email messages in a timely manner as appropriate
  • Comply with the dress code of The Geneva Foundation and assigned duty station
  • Promote positive, professional relationships with co-workers and The Geneva Foundation
  • Maintain and update files of all applicable regulatory documentation for IACUC or IRB (including protocols, approvals, amendments, modifications, etc.) as well as any communications with the sponsor or any other Federal or regulatory office (including prior approvals, change in scope, etc.)

 

 

 

Qualifications:

 

 

 

 

 

  • PhD or MD required
  • Biomedical , Mechanical , Bioengineering, Electrical engineer or similar degree
  • 1-2 years medical research project management experience strongly desired, preferably with Department of Defense
  • Knowledge of military system, preferred
  • Demonstrate competence in oral and written communication
  • Must be organized, attentive to detail, and possess a positive, friendly and professional demeanor
  • Ability to be flexible with changing priorities and available to interact with employees, clients and sponsors of all levels
  • Ability to exercise independent judgment in fast-paced, high-pressured environment with strict deadlines and to manage multiple projects
  • Computer skills including at least intermediate level experience with Excel and other Microsoft Office Software
  • Cell and/or tissue culture experience required
  • Experienced with 3D fluorescent confocal microscopy and electrospinning
  • Experienced with 3D bioprinting
  • Experience with micro fabrication
  • Experience with mechanical systems
  • Experience with materials testing
  • Experience in a wet lab environment
  • Knowledge of one or more of the following or similar software: LabView MATLAB Solidworks/CAD Cadence

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pharmacovigilence Scientist

Date Posted:
3/9/2017

Proctor and Gamble

OH

The Research and Development Division (R&D) is responsible for building and protecting P&G business and corporate reputation by ensuring our ingredients, products and packages are safe and viewed as such, in regulatory compliance and delivering against our global sustainability vision. As a member of the team, you will be responsibility to manage, monitor and understand in-market product safety for P&G products sold worldwide.

 

The Ideal Candidate

 

As The Pharmacovigilance Scientist, You Will Have Responsibility To Manage, Monitor And Understand In-market Product Safety For P&G Products Sold Worldwide In Order To

 

I. Ensure consumer safety and regulatory compliance

 

II. Enhance existing systems and improve current work processes for safety surveillance and

 

III. Analyze health related consumer complaints for signal detection and continual product improvement.

 

You will be the subject matter expert within Global Safety Surveillance & Analysis with respect to the in-market safety profile, symptom profile and special issues for your assigned product categories. You will obtain a good understanding of relevant regulations and will ensure that all regulatory submissions are processed in accordance with applicable regulations and requirements. You will be the product vigilance single point of contact for other P&G functions. You will be responsible for signal detection and signal management activities associated with your assigned product categories.

 

Qualifications

 

Qualifications and skills required are as follows:

 

  • An advanced degree in either a health care profession (e.g. Pharm. D., M.D.) or life science (PhD).
  • Good collaboration skills and experience in establishing and maintaining working relationships.
  • Excellent written and oral communication skills in English with an emphasis on communication of human health relevance, safety and clinical information. Experience with external communications to regulatory authorities and industry groups would be beneficial but is not essential.
  • Excellent organization skills, an attention to detail and an ability to manage complex systems.
  • Experience with databases, data reporting tools and statistical analysis would be beneficial.

     

Previous experience in product vigilance is desirable but not essential. What matters is your enthusiasm, your willingness to learn and your collaborative and interpersonal skills. There is always plenty of help, support, coaching and training available from colleagues, with formal training being tailored to your needs and interests.

 

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, protected veteran status, disability status, age, sexual orientation, gender identity and expression, marital status, citizenship, HIV/AIDS status or any other legally protected factor.

 

Immigration sponsorship is not available for this position. Applicants for U.S. based positions are generally required to be eligible to work in the U.S. without the need for current or future sponsorship. Except in rare situations based on Procter & Gamble's sole discretion. Procter & Gamble does not sponsor candidates for permanent residency. Any exceptions would be based on the Company's specific business needs at the time and place of recruitment as well as the particular qualifications of the individual.

 

Procter & Gamble participates in e-verify as required by law.

 

Qualified individuals will not be disadvantaged based on being unemployed.

 

**Please include your resume and a brief summary of your research in the resume text field (maximum characters 64,000).**

 

Job IDRND00003486


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PhD Scientist, Immunology

Date Posted:
3/9/2017

Vendata

MA

The Ph.D. will conduct in-vivo studies designed to assess the ability of commensal bacteria to induce immune responses in germ-free and conventional mice. The principal activities of this role will be to develop assays to evaluate molecular and cellular pathways of host-microbe interactions, execute high-throughput screens, and perform in vivoexperimental procedures using mouse models. Responsibilities also include the culturing and phenotypic characterization of human and murine primary immune cells. The job title and level will correspond to the experience and skills of the selected candidate.

Qualifications

  • Ph.D. in immunology with a focus on mucosal immunotherapy and the role of the microbiome. Research experience in autoimmunity and/or gastrointestinal inflammatory diseases a plus
  • Expertise in the use of germ -free mice as well as animal models of gut associated autoimmunity and inflammation desired
  • Previous research experience and basic immunological techniques (flow cytometry, ELISA, cell culture and phenotypic characterization of primary immune cells) as well as molecular biology methods (RNA and DNA isolation and analysis, PCR)
  • Highly motivated and organized individual with excellent communication skills
  • Strong publication record
  • Team player, able to work well in a group setting as well as independently in a fast paced environment.
  • General understanding of the field of the human microbiome is preferred but not required.

Job posted by

Spencer Ball 2nd

Vice President Talent Acquisition at PureTech Health

Job Poster Location

Greater Boston Area

Premium

Seniority Level

Associate

Industry

  • Biotechnology

Employment Type

Full-time

Job Functions

  • Science
  • Research

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Product Support Specialist

Date Posted:
3/9/2017

Illumina

MA

Do you want to make a difference? Illumina’s mission is to improve human health by unlocking the power of the genome. If that inspires you, let’s talk. We’ve built a culture fueled by innovation, collaboration and openness, and established ourselves as the global leader in DNA sequencing and array-based technologies. Our people and our technology change lives by driving advancements in life sciences, oncology, reproductive health, agriculture and other emerging markets. We are deeply passionate about what we do, because we know that our work has the power to improve lives.
We’re an established company with a track record of phenomenal growth. Our revenue grew from $10 million in 2002 to approximately $2.2 billion in 2015. Our growth isn’t just revenue, we’ve been hiring the best and the brightest. Perhaps that’s why MIT has ranked Illumina near the top of its World’s Smartest Companies list three years running, including #1 in 2014. If you thrive in a brilliant, fast-paced, and mission-driven environment, Illumina is the place for you – imagine the possibilities.
Position Summary
As a Product Support Scientist; you will play a key role enhancing Illumina’s unparalleled customer support by performing remote troubleshooting on complex application and consumable issues with front-line support staff. You will also monitor complaint trends and advocate for product improvements that impact customer satisfaction and field implementation. Responsibilities will also include develop, author, and dissemination of technical updates and field bulletins to the global support and Customer Solutions organization. A successful candidate will have demonstrated experience of inter-departmental work experience and familiarity with CRM and ERP systems. Candidates will receive extensive experience with Illumina’s cutting-edge products.
All About You
Responsibilities:
Effective communication among peers and colleagues across global regions and corporate structure
Monitor intake complaints related to product design, robustness and customer satisfaction issues
Assist Technical Support and Field Service & Support staff with remote resolution of complex support cases and travel to customer sites to assist with resolution of complex issues as needed
Elevate complex support issues through appropriate channels and participate in multidisciplinary teams to speed resolution
Coordinate sustaining product releases with minimal assistance
Update, edit and author technical documentation and process in conjunction with key business members and teams
Partner with departmental groups on new product launches and assist with preparation and training of front-line support staff
Moderate travel (up to 15%)
Requirements:
At least 5 years of commercial biotech/biomedical science industry experience preferred
Prior experience in an in-house or field support role preferred
Strong analytical, problem solving, and interpersonal skills
Clear vision and commitment to providing outstanding customer service
Working experience with SFDC and/or SAP; and familiarity with quality systems
Education
PhD, MS, or BS in Molecular Biology or Life Sciences related degree; or related work experience
Illumina believes that everyone has the ability to make an impact, and we are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information.
Seniority Level
Not Applicable

Industry
Biotechnology Research Medical Devices
Employment Type
Full-time

Job Functions
Information Technology


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Senior Scientist Immunometabolism

Date Posted:
3/9/2017

Pfizer

MA

A career at Pfizer offers opportunity, ownership and impact. All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.

 

 

Role Description

 

Pfizer I&I department aims to develop novel therapeutics in treating chronic inflammatory diseases, in particular RA, IBD and SLE. Emerging data suggest that dysregulated metabolism of immune cells underlies the pathogenesis of these diseases. This position has been created to support elucidation of key metabolic processes that drive inflammatory pathogenesis and to identify novel targets that can be targeted to develop next-generation of therapies. This person will apply state of the art RNA interference and genome editing techniques to manipulate metabolic pathways in both adaptive and innate immune cells and determine the impact on their in vitro and in vivo functions. This person will work as part of a team to drive the in-depth understanding of biology, validation of target and delivery of novel therapeutics as ultimate goal.

 

 

Responsibilities

 

*Design and perform experimental studies to understand the biology relevant to disease to enable target/pathway validation *Support the design and development of in vitro experiments using mouse and human immune cells. *Establish essential phenotypic assays, applying CRISPr/Cas9 and/or virally mediated RNAi and in vitro/in vivo models suitable for dissecting disease biology, screening and testing compounds or biologics *Work with project team as a key biologist to coordinate and perform biology related work for the development of novel therapeutics *Identify and evaluate novel therapeutic targets in collaboration with other colleagues including biologists, geneticists, chemists as well as by actively engaging external collaboration

 

 

Qualifications

 

* PhD plus 3-5 post-graduate years relevant academic/industrial experience in the area of immunology,molecular/cell biology, biochemistry, or other related biology area.

 

 

 

* Successful candidates would be able to demonstrate effective communication skills, independent thinking as well as a publication record

 

 

 

* Experience in isolating and culturing primary immune cells: Expertise in T cell differentiation, CFSE-based proliferation assays, co-culture assays, regulatory T cell suppression assays and ability to design and conduct antigen-specific stimulation assays such as ELISPOT is highly desired.

 

 

 

* In addition to routine immunological assays such as ELISA, intracellular staining, FACS, qRT-PCR etc. experience in metabolism-related assays such as bioenergetics profiling using the Seahorse analyzer would be highly valued.

 

 

 

* Experience with recombinant DNA transfections, lentiviral / retroviral transductions would be a definite plus.

 

 

 

* Ability to work with large numbers of samples obtained from in vivo studies: Isolation of cells from lymphatic and peripheral tissues, analyses of inflammatory mediators in serum / plasma, ex-vivo FACS based phenotypic and functional assays.

 

 

 

* Competent user of relevant software packages supporting the manipulation of data and experimental design - PRISM, Cloner, Office, etc

 

 

EEO & Employment Eligibility

 

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.


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Postdoctoral Fellow

Date Posted:
3/9/2017

Genentech

CA

The Position

 

A postdoctoral position is available for a candidate interested in pursuing genomics research. The successful candidate will have the opportunity to use bioinformatics, in vitro and in vivo approaches to dissect genetic alterations in cancer. You will have an opportunity to analyze large data sets from nextgen sequencing, CRISPR/CAS9 technologies, mass spectrometry, knock-out and/or transgenic mouse models to understand gene function and signaling. Those with experience in these areas and experience with large-scale genomics data are strongly encouraged to apply.

 

For recent publication from the group refer to Nat Genet. 2016 48:407-16, Nat Biotechnol. 2015 33:306-12, and Nat Genet. 2015 47:13-21

 

Information about the postdoctoral program at Genentech can be found at http://www.gene.com/careers/academic-programs/postdocs.

 

For more information on Somasekar Seshagiri lab, please visit: https://www.gene.com/scientists/our-scientists/somasekar-seshagiri

 

Who You Are

 

A Ph.D with a strong background in bioinformatics, molecular biology or cellular biology is required. Candidates for this position must have high quality first author publications from their Ph. D. work.

  •  

Who We Are

 

 

A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

 

The next step is yours. To apply today, click on the "Apply online" button below.

 

Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our


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Postdoc Cancer Research

Date Posted:
3/9/2017

Cold Spring Harbor

NY

Job description

Requisition Details

 

Requisition Information

 

Requisition Title Postdoctoral Cancer Research Training Opportunity

 

Requisition Number 01355-R

 

Opening Information

 

Job Status Full Time

 

Position Category Post Doctoral

 

Education Required Graduate Degree

 

Position Description

 

Experience Required Less than 1 year

 

POSTDOCTORAL CANCER RESEARCH TRAINING OPPORTUNITY AVAILABLE COLD SPRING HARBOR LABORATORY

 

Located on the North Shore of Long Island and celebrating its 125th year anniversary, Cold Spring Harbor Laboratory ( CSHL ), has a distinguished record of excellence in biological research and education. CSHL’s NCI Designated Cancer Center has been an integral part of the Laboratory’s research mission since 1987. We have a postdoctoral training position available in CSHL’s Cancer Gene Discovery and Cancer Biology Postdoctoral Research Training Program, supported by the National Cancer institute of the National Institutes of Health ( NIH ).

 

Cancer research at CSHL is devoted to understanding the fundamental biology of human cancer in order to improve the diagnosis and treatment of many major forms of the disease. The primary goal of the training program is to prepare the next generation of cancer biologists to pursue independent research that integrates cancer gene discovery with functional biology in order to facilitate the development of novel cancer therapeutic, diagnostic and/or preventive strategies. The program benefits from a collaborative and multidisciplinary research environment, an internal Executive Committee that includes trainee representation, and an independent External Advisory Board.

 

Features of the three-year research training program include courses, structured career development activities, research seminars, teaching opportunities, and hands-on research training experiences in laboratories affiliated with the CSHL Cancer Center. Postdoctoral trainees benefit from a small faculty to trainee ratio, an on-site internationally renowned scientific Meetings and Courses Program, and newly expanded state-of-the-art cancer research facilities.

 

Cancer research opportunities span four highly integrated areas that include cancer; 1) Genetics – sequencing, genetic models, chromosome engineering; CRISPR /Cas9, single cell analysis; 2) Gene Regulation and Cell Proliferation – splicing, replication, epigenetics, nuclear structure, tumor growth and metastasis; 3) Signal Transduction and Human Cancer Impact – drug sensitivity and resistance, clinical correlates, disease status and outcomes; and 4) Quantitative Biology – population genetics, genome structure and evolution.

 

Position Requirements

 

Eligibility-

 

By The Time Of Appointment, Applicants Must

 

 

  • Be interested in preparing for a career as an independent cancer researcher
  • Have received a Ph.D., M.D., or comparable doctoral degree from an accredited domestic or foreign institution
  • Be within the first three years of postdoctoral training
  • Be a citizen, or a non-citizen national of the U. S. or have been lawfully admitted for permanent residence

     

(eligibility requirement of the National Institutes of Health ( NIH ), Ruth L. Kirschstein, National Research Service Award- NRSA )

 

 

How To Apply

 

Please apply as soon as possible by sending a letter of introduction, along with a curriculum vitae and the names of three individuals who can provide letters of recommendation to: http://cshl.peopleadmin.com/postings/9250

 

Only candidates selected for an interview will be contacted.

 

For any questions pertaining to this opportunity please email your inquiry to osp@cshl.edu.

 

For more information about CSHL and our cancer research program, please visit http://www.cshl.edu/Research/Cancer/Cancer-Center.html

 

Requisition Specific Questions

 

Required fields are indicated with an asterisk (*).

 

 

  • * Please list in chronological order any graduate or professional schools attended, your degree(s) (eg. PhD, MD, DVM), noting the location and date the degree was or is expected to be awarded. (Please refrain from referring to other documents)

     

(Open Ended Question)

 

 

 

  • * Please list any previous postdoctoral or residency training experience (if applicable). Please refrain from referring to other documents.

     

    (Open Ended Question)

     

  • * Please provide the title of your doctoral thesis and the name of your thesis advisor(s). Please refrain from referring to other documents.

     

    (Open Ended Question)

     

  • * How many months/years of postdoctoral training experience do you have?

     

    (Open Ended Question)

     

  • * Please indicate the fields that you are interested in seeking training in at CSHL (check all that apply):

     

    • Cancer genetics
    • Cancer related signal transduction
    • Cancer related gene regulation and cell proliferation
    • Cancer related Quantitative Biology
  • * If you are authorized to work for all employers in the US on a full time basis, will you now or in the future require sponsorship for an employment-authorized visa status?

     

      • Yes
      • No

     

Applicant Documents

 

 

Required Documents

  • Resume or Curriculum Vitae
  • Cover Letter

Optional Documents

 


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Senior Scientist CRISPR

Date Posted:
3/9/2017

GQR Global Products

MA

My Client a VC Backed drug discovery company employing cutting-edge functional genomics technology to identify novel pathways and targets involved in oncology and immuno-oncology. is seeking talented scientists.

 

 

 

We’re looking for exceptional PhD level immunologists. You’d be part of a team with deep expertise in immunology, functional genomics, oncology, and drug discovery.

 

 

 

We’re looking for candidates that have extensive experience culturing/manipulating lymphocytes and performing functional immunoassays, both in vitro and in vivo.

 

 

 

  • PhD with a postdoctoral fellowship in immunology or oncology with a focus on molecular immunology.

     

  • Technical expertise in gene editing immune cells desired.

     

  • 0-3 years of experience in an industrial setting with a focus on immuno-oncology a plus.

     

  • Experience managing scientists.

     

  • Proficiency in a wide range of immunological laboratory techniques.

     

  • A track record of communicating scientific concepts and strategies effectively, including a publication record in top-tier, peer reviewed journals.

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Genomics Product Specialist

Date Posted:
3/9/2017

Agilent

MD

Job description

Agilent is the premier laboratory partner for a better world. We provide life science, diagnostic and applied market laboratories worldwide with instruments, services, consumables, applications and expertise. Agilent enables customers to gain the insights they seek -- so they can do what they do best: improve the world around us. Information about Agilent is available at www.agilent.com.

 

The Diagnostic and Genomics Group (DGG) at Agilent is seeking an experienced, enthusiastic, self-motivated and people-oriented individual to join our successful and dynamic Americas Field Operations (AFO) team as a Product Specialist.

 

In a direct sales role, as a Genomics Product Specialist, you will be responsible for driving sales of Agilent Technologies' line of high performance Microarray, NGS Automation, CRISPR/Cas9 Gene Editing and Next Generation Sequencing (NGS) products and associated software solutions within this territory. As an integral member of the field sales team, you will use your excellent technical sales track record to focus on acquiring new customers while retaining and growing the existing installed base of customers. As the Product Specialist, you will be expected to develop and implement successful strategies and tactics to sell complex Genomic solutions within this competitive marketplace. In collaboration with your regional Genomics team, you will also maintain and expand relationships with strategically important large customers in the assigned territory, such as key research institutes, pharmaceutical companies, consortia and other organizations, in line with Agilent's corporate strategy.

 

Key Responsibilities

 

  • Driving sales of high performance Genomic products and services in a defined territory
  • Conduct presentations and product usage demos with and without Field Applications Scientist (FAS) assistance
  • Contribute to developing effective strategies and tactics that will enable Agilent to gain market share in the Territory
  • Focus on strategic product applications (NGS, Gene Expression, CGH, CRISPR) and solutions in strategic accounts
  • Provide constructive feedback from customers into Agilent to help guide continual development of products that more effectively address customers' needs
  • Participate and be an active member in regional discussion groups and forums
  • Understand Genomics in Basic Science, Clinical Research, Government/Non-Profit, and Biotech/Pharmaceutical market segments and recognize trends that impact buying of Agilent products
  • Develop and maintain strategic customer relationships
  • Represent Agilent to the customer AND the customer to the company

     

Agilent inspires and supports discoveries that advance the quality of life. We provide life science, diagnostic and applied market laboratories worldwide with instruments, services, consumables, applications and expertise. Agilent enables customers to gain the answers and insights they seek –– so they can do what they do best: improve the world around us. Information about Agilent is available at www.agilent.com.

 

Requirements

 

  • BS/MS in a Life Sciences discipline, or equivalent; advanced degree preferred;
  • 5+ years related direct sales experience with a demonstrated track record of successfully selling against a quota
  • High level of experience in microarrays and/or NGS
  • Technical knowledge and domain knowledge in the research and diagnostic sector of the pharmaceutical industry (profit and not for profit). Knowledge of the clinical research marketplace
  • Industry/Application expertise. Working knowledge of competitive products (specifications, value propositions, price points)
  • Comfortable interfacing with senior managers within your accounts.
  • Demonstrated commercial selling skills. Strong business development, negotiation and closing skills.
  • Effective interpersonal communication and telephone sales skills.
  • Solid self-management and organizational and prioritization skills
  • Must be able to travel up to 50% of the time.

     

Agilent Technologies, Inc. is an Equal Employment Opportunity and Affirmative Action employer. We value diversity at all levels. All individuals, regardless of personal characteristics, are encouraged to apply. All qualified applicants will receive consideration for employment without regard to sex, pregnancy, race, religion or religious creed, color, gender, gender identity, gender expression, national origin, ancestry, physical or mental disability, medical condition, genetic information, marital status, registered domestic partner status, age, sexual orientation, military or veteran status, protected veteran status, or any other basis protected by federal, state, local law, ordinance, or regulation and will not be discriminated against on these bases.

 

For more information about equal employment opportunity protections, please view the ‘EEO is the Law’ poster available here:

 

https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf,

 

https://www.dol.gov/ofccp/regs/compliance/posters/pdf/OFCCP_EEO_Supplement_Final_JRF_QA_508c.pdf

 

Agilent Technologies, Inc., is committed to diversity in the workplace and strives to support candidates with disabilities. If you have a disability and need assistance with any part of the application or interview process or have questions about workplace accessibility, please contact +1-262-754-5030 (US and Canada only) or email job_posting@agilent.com. EOE AA M/F/Vet/Disability

 

Desired Skills and Experience

 

Qualifications:

 

 

 

Requirements:

 

- BS/MS in a Life Sciences discipline, or equivalent; advanced degree preferred;

 

- 5+ years related direct sales experience with a demonstrated track record of successfully selling against a quota

 

- High level of experience in microarrays and/or NGS

 

- Technical knowledge and domain knowledge in the research and diagnostic sector of the pharmaceutical industry (profit and not for profit). Knowledge of the clinical research marketplace

 

- Industry/Application expertise. Working knowledge of competitive products (specifications, value propositions, price points)

 

- Comfortable interfacing with senior managers within your accounts.

 

- Demonstrated commercial selling skills. Strong business development, negotiation and closing skills.

 

- Effective interpersonal communication and telephone sales skills.

 

- Solid self-management and organizational and prioritization skills

 

- Must be able to travel up to 50% of the time.

 

Agilent Technologies, Inc. is an Equal Employment Opportunity and Affirmative Action employer. We value diversity at all levels. All individuals, regardless of personal characteristics, are encouraged to apply. All qualified applicants will receive consideration for employment without regard to sex, pregnancy, race, religion or religious creed, color, gender, gender identity, gender expression, national origin, ancestry, physical or mental disability, medical condition, genetic information, marital status, registered domestic partner status, age, sexual orientation, military or veteran status, protected veteran status, or any other basis protected by federal, state, local law, ordinance, or regulation and will not be discriminated against on these bases.

 

For more information about equal employment opportunity protections, please view the ‘EEO is the Law’ poster available here:

 

https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf,

 

https://www.dol.gov/ofccp/regs/compliance/posters/pdf/OFCCP_EEO_Supplement_Final_JRF_QA_508c.pdf

 

Agilent Technologies, Inc., is committed to diversity in the workplace and strives to support candidates with disabilities. If you have a disability and need assistance with any part of the application or interview process or have questions about workplace accessibility, please contact +1-262-754-5030 (US and Canada only) or email job_posting@agilent.com. EOE AA M/F/Vet/Disability


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Equity Research Associate

Date Posted:
3/9/2017

Evercore

NY

We are hiring an associate to support our pharma and biotech (Small and Large cap) coverage.

 

Responsibilities:

The candidate will work on a team with other associates to support the senior research analyst in the coverage of biotechnology and pharmaceutical companies. Key responsibilities will include building and maintaining financial models, creating in-depth analyses and research reports and rapidly analyzing how investment theses change after material events.

This position is located in New York.

 

Experience and Qualifications:

¦ Advanced science degree: an MD or PhD in the biosciences is preferred

¦ Strong financial modeling skills required (meaning can easily build an integrated I/S, B/S, CFS and DCF forward-looking model in Excel)

¦ Demonstrated achievement of excellence (really high grades / test scores; prior promotions, etc, etc)

¦ Strong analytical skills (financial and mathematical)

¦ Strong communication skills

¦ Hard working, willing to work long hours

¦ Team player with collegial attitude

 

About Evercore ISI:

Established in 1995, Evercore is a leading global independent investment banking advisory firm. Evercore advises a diverse set of investment banking clients on a wide range of transactions and issues and provides institutional investors with high quality equity research, sales and trading execution that is free of the conflicts created by proprietary activities. The Firm also offers investment management services to high net worth and institutional investors. With 27 offices and affiliate offices in North America, Europe, South America and Asia, Evercore has the scale and strength to serve clients globally through a focused and tailored approach designed to meet their unique needs. More information about Evercore can be found on the Company’s website at www.evercore.com

 

 

To Apply:
Please apply with your resume and reference "Equity Research Candidate.”

Apply through https://www.dropoutclub.org/jobs/list/


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Equity Research Fellowship

Date Posted:
3/6/2017

Goldman Sachs

NY

Job Summary & Responsibilities

GOLDMAN SACHS FIRM OVERVIEW
The Goldman Sachs Group, Inc. is a leading global investment banking, securities and investment management firm that provides a wide range of financial services to a substantial and diversified client base that includes corporations, financial institutions, governments and high-net-worth individuals. Founded in 1869, the firm is headquartered in New York and maintains offices in London, Frankfurt, Tokyo, Hong Kong and other major financial centers around the world.

DIVISIONAL OVERVIEW
Global Investment Research (GIR) provides investment recommendations by generating fundamental research and analysis of companies, industries, markets and economies. GIR analysts help our clients achieve superior returns through our creative, differentiated investment insights and ideas. Our clients include mutual funds, hedge funds and pension funds, among others.

Goldman Sachs is seeking PhD candidates or graduates with non-finance backgrounds to participate in a 6 month fellowship. The Fellowship will enable PhDs to explore a potential career transition into Equity Research. The Fellows are provided with training and hands-on experience on a research team as well as networking and mentorship opportunities.  The Fellowship:

•             Is open to PhDs in math, technology, or science related disciplines
•             Does not require finance experience however, an interest in investing or a basic knowledge of the markets is helpful.

SAMPLE RESPONSIBILITIES
•             Build and maintain financial models
•             Market share, macro trend, and cross company and sector data analyses
•             Company specific projects
•             Update monthly reports, marketing books, and weekly reports
•             Update and maintain daily valuation sheets

 

 

Preferred Qualifications

•             Excellent verbal and written communication skills
•             Meticulous attention to detail and strong organizational skills
•             Exceptional analytical skills, lateral thinking, and judgment
•             A proactive approach and a high level of enthusiasm
•             Experience with Microsoft Office applications (Excel, Word, Outlook)
•             Ability to meet aggressive deadlines


Goldman Sachs is an equal employment/affirmative action employer Female/Minority/Disability/Vet.  © The Goldman Sachs Group, Inc., 2015.  All rights reserved.


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Teaching Postdoc

Date Posted:
3/6/2017

Loyola University

MD

nclusive Excellence Postdoctoral Teaching Fellow
Faculty Type Non Tenure Track Fulltime
Office/Department School of Education
If Temporary or Visiting, Estimated End Date: 06/08/2019
Position Duties

Fellows teach two courses in Loyola’s undergraduate and graduate programs per semester—such as STEM-related methods, research methods and design, and learning sciences—and will also be provided time and resources to establish a research agenda. Fellows are partnered with both a School of Education department mentor and a University mentor to support their teaching and scholarship. It is expected that Fellows become active members of the School of Education community by fulfilling other service responsibilities, such as collecting accreditation data, and supporting student initiatives and departmental events.

Required Qualifications

(1) an earned doctorate in education or closely related field by August 2017; (2) successful teaching experience in K-12 settings; (3) knowledge of national standards and trends in education; and (4) evidence of participation in professional organizations. Applicants should also possess an awareness of and interest in the educational mission of Jesuit higher education. Eligible candidates must have received their Ph.D. no earlier than 2013. The two-year Fellowships include research funds, comprehensive mentorship, and access to a consortium of postdoctoral diversity programs at participating Jesuit institutions.

Preferred Qualifications

(1) experience with urban education, particularly within culturally and linguistically diverse contexts; and (2) experience teaching undergraduate or graduate courses.

Job Posting Date 02/01/2017
Priority Application Deadline Date 03/15/2017
Job Close Date  
Anticipated Start Date 08/24/2017
University Description

Loyola University Maryland is a Jesuit, Catholic university committed to the educational and spiritual traditions of the Society of Jesus and to the ideals of liberal education and the development of the whole person. Accordingly, Loyola inspires students to learn, lead, and serve in a diverse and changing world. Loyola’s beautiful, historic Evergreen campus is located in Baltimore, and its graduate centers are in Timonium and Columbia. Loyola enrolls 4,000 undergraduate and 2,000 graduate students across the Sellinger School of Business and Management, the School of Education, and Loyola College of Arts and Sciences. Founded in 1852, Loyola is one of 28 Jesuit colleges and universities in the United States and the first to bear the name of Saint Ignatius Loyola, founder of the Society of Jesus.

Diversity Statement

Loyola University Maryland strongly values the benefits that diversity brings to the workplace. In accord with its Ignatian values, the University is committed to creating and promoting a community that recognizes the inherent value and dignity of each person. Loyola University Maryland does not discriminate on the basis of race, sex, color, national or ethnic origin, age, religion, disability, marital status, sexual orientation, gender identity, genetic information, military status, or any other legally protected classification. The University recruits, hires, and promotes in accord with this policy and its Core Values.

Special Instructions to Applicants

Use “Option 1” for the teaching philosophy statement.

Successful candidates for any staff, faculty, or administrative position at Loyola University Maryland will be subject to a pre-employment background check.

Quicklink for Posting http://careers.loyola.edu/postings/2657

Applicant Documents


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Scientist III Cell Biology

Date Posted:
3/6/2017

Thermo FIsher

MD

Job Description
Job Title: Scientist III, Cell Biology
Location: Frederick, MD
Reports to: Sr. Staff Scientist, Cell Biology, Cell Biology

When you’re part of the team at Thermo Fisher Scientific, you’ll do important work, like helping customers in finding cures for cancer, protecting the environment or making sure our food is safe. Your work will have real-world impact, and you’ll be supported in achieving your career goals.

We are looking for a highly skilled and motivated individual to join Cell Biology for Scientist III position focused on commercialization of products in the area of hepatic and cell biology. Key areas of research for this position will include development of more advanced cell culture technologies within the hepatic space with a focus on hepatocyte and NPC isolation and culture.

Specific duties for this position will include:

  • Leading major R&D project(s), designing and executing experiments while working in cross-functional product commercialization teams.
  • Troubleshooting experiments and presenting data to project teams and management.
  • Identifying and solving complex problems associated with key experimental and project goals, and contributing ideas to improve on existing protocols, processes and approaches.
  • Maintain scientific visibility and credibility by active familiarization with literature directly associated with the assigned projects, maintaining familiarity with the state of the art approaches and publishing in peer reviewed journals.
  • Comply with all company safety regulations and procedures.
  • A successful candidate will have the ability to effectively handle multiple tasks and learn quickly.
  • Effective communication skills and the ability to work in team environment are essential.


Education

  • PhD or MS in Molecular and/or Cell Biology, or other related fields


Minimum Qualifications:

  • Strong knowledge in hepatic biology and ADME/Tox.
  • Strong animal surgical and handling work experience.
  • Experience in primary hepatocyte isolation and culture from human tissue and rodents.
  • Willingness to learn new surgical techniques and survival surgeries in small animals.
  • Experience in basic molecular biology including PCR, Western blot, and ELISA required.
  • Strong publication record desirable
  • Ability to work in dynamic, fast paced team environment
  • Effective communication/interpersonal skills
  • Able to design, execute, and analyze experiments with a low level of supervision required
  • Maintain and document laboratory protocols and notebooks
  • Perform other related duties as required and/or assigned
  • The position will require non-standard working hours (evenings and weekends) due to the unpredictable nature of tissue availability as well as for maintenance of cell culture experiments based on projects assigned


This position has not been approved for Relocation Assistance.

At Thermo Fisher Scientific, each one of our 50,000 extraordinary minds has a unique story to tell. Join us and contribute to our singular mission—enabling our customers to make the world healthier, cleaner and safer. Apply today http://jobs.thermofisher.com

Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.

*IND-LSG


Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.


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Lab Research manager Center for Vaccine Development

Date Posted:
3/6/2017

University of Maryland

MD

The University of Maryland, Baltimore (UMB), Center for Vaccine Development (CVD) is seeking a Laboratory Research Manager to manage a vaccine development project. The candidate will coordinate laboratory activities to develop a new vaccine. The candidate will work in a highly collaborative environment to achieve the project goals. The candidate will also perform laboratory experiments including genetic engineering of bacteria, animal experiments and assessment of antibodies elicited by the vaccine. The candidate will oversee and train staff, maintain and manage documents including reports and will communicate with external investigators. This position has the authority to formulate, affect, interpret, or implement management policies or operating practices.

 

Benefits Information

 

UMB offers a generous benefits package that includes 22 vacation days, 14 floating and holidays, 15 sick days; comprehensive health insurance and retirement options; and tuition remission for employees and their dependents at any of the University System of Maryland schools.

 

Essential Functions

  • Manage laboratory staff including training, scheduling, coordinating and delegating work, monitoring and evaluating performance to promote maximum staff member benefit and effectiveness as well as overall functional productivity.
  • Manage the development and execution of project research studies. Revises studies, in consultation with upper management or principal investigator, to meet changing needs and requirements and enforces standards.
  • Manage laboratory operations including the budget, ensuring quality control and safety compliance, developing policies and procedures, and ordering supplies. Identify and address issues and deficiencies and implement effective solutions.
  • Perform laboratory maintenance and laboratory research activities required by the study(s).
  • Assemble and assist with literature research, editing and preparing manuscripts, scientific illustrations and computer graphics for publication.
  • Provide for establishment or development of laboratory by evaluating equipment or machinery to be ordered, planning interactions with IT systems, and drafting Standard Operating Procedures for using new equipment.
  • Foster and support a conducive consultant/client environment, providing business unit and campus representatives with assessment, training, and advisement in research area.
  • Perform other related duties as assigned.
 
Qualifications
  

Education: Bachelor’s degree in Biology, Chemistry or field of study related to the research of the laboratory.

 

Experience: Six (6) years of experience in laboratory research including four (4) years in microbiology, immunology or molecular biology.

 

Supervisory: Two (2) years of direct supervision or responsibility for training, work coordination, and monitoring the work of others.

 

Preferred: PhD in biology, microbiology, immunology or related field is preferred.

 

Knowledge, Skills, and Abilities

  • Possess knowledge of vaccines and immunotherapeutic as well as Good Laboratory Practices (GLP) and documentation. Able to perform position in compliance with all requirements, regulations, and laws. Ability to maintain high standards with the work being performed and maintain awareness with trends and influences. Ability to understand and utilize scientific/medical terminology and research theory in both verbal and written communications. Assumes personal responsibility for all outcomes; makes effective and timely decisions; and learns how to effectively use technology. Maintains productivity and uses knowledge strategies to increase knowledge base.
  • Ability to effectively communicate both verbal and written thoughts, ideas, and facts. Interprets and understands written information and is able to listen attentively to verbal and non-verbal cues that lead to a deeper understanding. Ability to maintain confidentiality of subjects and information obtained.
  • Ability to work cooperatively with others and demonstrates professional, ethical, respectful, and courteous behavior when interacting with others. Demonstrate pleasant and positive interactions with other to meet customer expectations, and provide follow up with customers. Reaches compromise and consensus to influence and negotiate. Remains calm and is able to manage conflict, and works well with a diverse workforce. Approachable style allows others to be open in sharing thoughts and ideas. Able to make independent decisions that are a matter of significance for the unit.

 

Hiring Range: Commensurate with education and experience

 

If accommodations are needed for a disability, please contact Staffing & Career Services at 410-706-2606, Monday – Friday, 8:30am – 4:30pm EST. Maryland Relay can be accessed by dialing 711 (in-state) or 1-800-735-2258.

 

Equal Opportunity/Affirmative Action Employer. Minorities, women, protected veterans, and individuals with disabilities are encouraged to apply.

 

Job

: Exempt Staff - E3327F
Employee Class : Exempt Regular
Full Time/Part Time: Full-Time

Shift

: Day Job
Financial Disclosure: No

Organization

: Medicine

Job Posting

: Feb 22, 2017

Unposting Date

: Mar 13, 2017, 10:59:00 PM

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Sr. Technology Licensing Associate

Date Posted:
3/6/2017

JHU

MD

Sr. Technology Licensing Associate

Classified Title: Sr. Technology Transfer Associate

Requisition #: 311971

Range: PG

Level: 4

Salary: $89,557 - $123,187

Status: Full Time

School: Academic Centers

Location: JH at One Charles Center

Location City: Baltimore

Location State: MD

Resume Required for Application: Yes

Area of Interest: Other

Contact: Human Resources 443-997-5100

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General Description

 

Reporting to a Director of Licensing, this person independently manages a portfolio of life science technologies in order to source, negotiate and execute high value, intellectual property licenses.

Essential Job Functions:
  • Provides sell-side and business development activities around intellectual property commercialization.
  • Develops positive relationships with inventors with the intention of identifying attractive JHU technologies for licensing to start up or established companies.
  • In concert with peers, makes decisions around patenting, marketing and licensing of JHU inventions.
  • Engages with investors and companies to determine their needs and identifies applicable JHU technologies for licensing.
  • Negotiates high value intellectual property licenses for optimal deal structure, valuation and compliance.
Scope of Responsibility
  • Works under the direct supervision of a Director of Licensing in evaluation, marketing and agreement negotiation activities. May manage or mentor junior personnel as assigned.
Decision Making
  • Makes recommendations concerning investments in technologies.
Authority
  • May direct the activities of staff or a function. May not commit JHU to agreement terms without supervisor approval.

 

Qualifications

 

An advanced degree in the life sciences, or business required. PhD, or combination of degree in life sciences with an MBA strongly preferred.

Candidate will have licensing experience in a high performing technology transfer office that is typically gained through a minimum of 4 years of licensing and technology transfer experience; and/or a startup or biotechnology company with business development and deal execution experience.

Candidate will have a working knowledge of intellectual property prosecution, technology valuation and license structure. Most importantly, candidate will have a robust deal sheet of exclusive licenses and options of life science technologies.

Required Skills:

  • Must have the ability to understand complex technologies.
  • Must have knowledge and experience in negotiating business contracts, especially in technology licensing.
  • Knowledge and experience in life sciences or physical sciences preferred.
  • Experience in marketing and sales of intellectual property desired.
  • Must have the ability to work independently and as a member of a team.
  • Must demonstrate outstanding work ethic and desire and ability to work in fast-paced high-expectation environment.
  • Must be a self-starter capable of handling a docket of highly technical inventions, managing a complex patent portfolio, and marketing and licensing technology with minimal supervision.

 


NOTE: The successful candidate(s) for this position will be subject to a pre-employment background check.

If you are interested in applying for employment with The Johns Hopkins University and require special assistance or accommodation during any part of the pre-employment process, please contact the HR Business Services Office at 443-997-5100. For TTY users, call via Maryland Relay or dial 711.


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Proteomics Mass Spec Senior Technical Specialist

Date Posted:
3/6/2017

KAUST

INT

Proteomics/Mass Spectrometry - Senior Technical Specialist KAUST is an international university dedicated to advance science and technology through innovative and collaborative research and addressing challenges of regional and global significance. Based near Jeddah, Saudi Arabia, KAUST has attracted top-notch faculty and staff from all over the world, especially from countries such as USA, Germany, China, the UK, Australia, Japan, and Italy. Citizens from more than 100 nations are represented on the university campus and in the KAUST community. We are currently seeking a Senior Technical Specialist for Proteomics at the Bioscience Core Laboratory (BCL). The laboratory covers different areas such as genomics, proteomics, protein expression, and bioinformatics. The laboratory is state-of-the-art, and our team members have extensive experience in the technological areas. For Proteomics the lab holds Orbitrap Fusion Lumos, QExactive HF, TripleTOF 5600, Maxis Q-TOF and Ultraflex MALDI-TOF/TOF. Job Summary: The senior technical specialist in this role will be working on high-throughput proteomics. The person demonstrates expertise and independent working knowledge in a range of techniques including sample preparation for proteomics, hands-on LC-MS and proteomics data analysis. The person works closely with the team lead and other members of the core unit. The work involves method development, assay assessments and standardized experiments. We are a core lab facility and the working environment and mentality is service- and support-oriented in a cooperative spirit. The person in this position must be open to a fast-changing environment, and willing and supportive of alterations. Major Responsibilities: ? Provide consultation to scientists and students ? Run standardized and customized proteomics sample preparation independently ? Operate standardized and customized analysis on sophisticated LC-MS ? Train users on sample preparation, equipment and data analysis ? Expand methods and protocols for proteome sample and data analyses ? Obtain and deliver reliable and excellent quality of data and results at all times ? Maintain and manage the mass spectrometry equipment ? Identify gaps and provide feedback to all technical aspects of proteomics portfolio, or suggestions for improvements ? Collaborate efficiently with other groups internally and externally ? Stay-up-to-date with new technologies Competencies: ? A bachelor degree or above in cell biology, biochemistry, molecular biology or similar ? Minimum 2 years of experience in mass spectrometry based proteomics ? Experience in analyzing large-scale proteomics data or ability to write script is a plus ? Independently perform preventative maintenance and ability to troubleshoot equipment ? The desire to work in a team dedicated to achieving highest quality analytical results ? Ability to work with others, initiative, and ability to interact with a broad range of individuals within the University and Industrial partners and be reliable Located on the beautiful Red Sea coast of Saudi Arabia, KAUST sets exceptional standards in residences, recreational facilities and boasts a truly multicultural environment which can be enjoyed by all. Life on the Campus provides ample opportunities and time to keep work and life in harmony – from vacations and holidays to an inviting campus community on the shores of the Red Sea, with all the seaside amenities and recreation facilities of a fine resort. Employees are very well looked after, with packages including tax-free salary, relocation, accommodation and various additional incentives. Contact: stine.buechmannmoeller@kaust.edu.sa Core Labs website: https://corelabs.kaust.edu.sa/ KAUST website: https://www.kaust.edu.sa/en Live and work at KAUST: https://www.kaust.edu.sa/en/live-work


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Single Cell Genomics Scientist Flow Cytometry

Date Posted:
3/6/2017

KAUST

INT

Single Cell Genomics Scientist with flow cytometry experience KAUST is an international university dedicated to advance science and technology through innovative and collaborative research and addressing challenges of regional and global significance. Based near Jeddah, Saudi Arabia, KAUST has attracted top-notch faculty and staff from all over the world, especially from countries such as USA, Germany, China, the UK, Australia, Japan, and Italy. Citizens from more than 100 nations are represented on the university campus and in the KAUST community. We are currently seeking a Scientist for Single Cell Genomics at the Bioscience Core Laboratory (BCL). The laboratory covers different areas such as genomics, proteomics, protein expression, and bioinformatics. The laboratory is state-of-the-art, and our team members have extensive experience in the technological areas. For Single cell analysis the lab holds BD influx, Fluidigm C1, Biomark HD, and a Chromium (10X genomics). Job Summary: The scientist in this role will be the primary team member working on single-cell analysis. The scientist demonstrates scientific and operational expertise in a range of techniques related to cell sorting, genomics and gene expression analysis. The person in this role works closely with the team lead and other members of the core unit. The work involves method development, assay assessments and standardized experiments. We are a core lab facility and the working environment and mentality is service- and support-oriented in a cooperative spirit. The person in this position must be open to a fastchanging environment, and willing and supportive of alterations. Major Responsibilities: ? Operate multi-parameter flow cytometers, high speed cell sorter, data acquisition and analysis as used in environmental and biomedical research ? Operate other types of equipment such as single-cell platforms, sequencing and qPCR instruments. ? Provide consultation to scientists and students ? Maintain and manage the flow cytometry equipment as well as single-cell platforms ? Train users on equipment ? Exhibit the highest degree of reliability and accuracy to assure quality results ? Stay-up-to-date with newest technologies ? Collaborate efficiently with other groups internally and externally to set up new projects on a high scientific level ? Expand methods for sample analyses and the knowledge to other technologies or scientific challenges as well as new project opportunities Competencies: ? A PhD degree in cell biology, biochemistry, molecular biology or similar ? Minimum 3 years of experience in flow cytometry. ? Extensive experience in high performance and multi-color fluorescence activated cell sorting will be a plus. ? Insight into NGS libraries and microfluidics platforms ? The desire to work in a team dedicated to achieving highest quality analytical results ? Ability to work with others, initiative, and ability to interact with a broad range of individuals within the University and Industrial partners and be reliable Located on the beautiful Red Sea coast of Saudi Arabia, KAUST sets exceptional standards in residences, recreational facilities and boasts a truly multicultural environment which can be enjoyed by all. Life on the Campus provides ample opportunities and time to keep work and life in harmony – from vacations and holidays to an inviting campus community on the shores of the Red Sea, with all the seaside amenities and recreation facilities of a fine resort. Employees are very well looked after, with packages including tax-free salary, relocation, accommodation and various additional incentives. Contact: stine.buechmannmoeller@kaust.edu.sa Core Labs website: https://corelabs.kaust.edu.sa/ KAUST website: https://www.kaust.edu.sa/en Live and work at KAUST: https://www.kaust.edu.sa/en/live-work


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Research Support Specialist Proteomics

Date Posted:
3/6/2017

Rockfeller University

NY

Job opening in the Proteomics Resource Center at The Rockefeller University The Rockefeller University, a world-renowned center for research and graduate education in the biomedical sciences seeks a Research Support Specialist to join the Proteomics Resource Center (PRC) (http://proteomics.rockefeller.edu/). The PRC is currently staffed with five scientists and equipped with state-of-the-art instrumentation, including a Q-Exactive Plus and a Fusion Lumos. PRC staff work and collaborate on a wide variety of projects with Rockefeller investigators as well as with scientists from other not-for-profit institutions. Samples ranges from small molecules over parts-of-a-protein to thousands of proteins. Examples of projects include nucleoside quantitation, analysis of secreted mosquito peptides, and quantitative profiling of exosomes. The PRC has a detail-oriented style and addresses projects individually; this allows the staff to engage with many researchers and tackle a broad range of research areas. The Research Support Specialist position is ideal for a scientist with hands-on LC-MS/MS experience who has or wishes to gain additional proteomics and small molecule experience in an exciting and high-impact scientific environment. Responsibilities • maintaining and operating nano-flow and high-flow LC-MS and related equipment • interacting with and advising investigators with regard to proteomics experiments • developing and implementing technologies in the Center • processing, analyzing, and interpreting data and reporting findings to investigators and the Director • generating standard operating procedures • tracking and submitting billing and purchasing information • monitoring and maintaining laboratory appearance • this position reports directly to the Director of the Center Who you are • Bachelor’s degree in science required, master or higher preferred. Educational emphasis in mass spectrometry, analytical chemistry or a related field preferred • strong analytical and practical skills in protein sample preparation, nano-flow LC-MS, and data analysis and interpretation • excellent communication skills in oral and written English • ability to work independently as well as part of a team, and flexibility to interact with a diverse group of researchers • in-depth experience with protein identification, quantitation, de novo sequencing, and characterization of post-translational modifications • hands-on experience with mass spectrometry, preferably Orbitrap type instruments, in-depth knowledge of instrument operation and maintenance, data interpretation, and knowledge of background literature • practical experience with bioinformatics and “global proteomics” is desirable • ability to maintain and expand knowledge of mass spectrometry techniques through self-education, dialog with other experts, reading literature, and attending conferences and courses as necessary Who we are The Rockefeller University is the world’s leading biomedical research University. Our groundbreaking discoveries in basic and clinical research are transforming medicine. We share a singular commitment to advancing science for the benefit of humanity and our collaborative community drives each of us to achieve a higher level, fueling the breakthroughs for which we are known. Our culture: • inspiring, collaborative atmosphere • strong social and environmental consciousness • intellectually curious academic environment • 14-acre campus setting on the Upper East Side of Manhattan How to Apply We offer an excellent benefits package, a competitive salary, and a beautiful working environment. Applicants should submit a cover letter and resume: http://www.rockefeller.edu/hr/jobs. Reference position IRC19730. The Rockefeller University is an Equal Opportunity Employer - Minorities/Women/Disabled/Veterans


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Genomics Lab Group Leader

Date Posted:
3/6/2017

David H Murdoch Research Center

NC

Job Description
As the Genomics Laboratory Group Leader, you will collaborate with academic, industry and government partners on the North Carolina Research Campus (NCRC) and beyond. These collaborations will include study design, data generation and analysis using next generation sequencing and microarray-based approaches for whole genome, exome and targeted sequencing, methylation profiling and gene expression analysis both at the aggregate and single cell levels. The successful candidate will manage all aspects of projects, from shipment and receipt of sample to data delivery, ensuring that projects are completed on time and within budget. As the Group Leader, you will develop standard operating procedures within a controlled document environment, conduct quality control assays, monitor process control and work with the bioinformatics team to perform data analysis.
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Job Requirements


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Job duties include, but are not limited to:
? Assisting Principal Investigators with the design, execution and interpretation of large-scale projects.
? Communicating ongoing project progress and acting as the key interface to scientific customers.
? Performing method design as required
? Effectively managing customer projects including allocating appropriate resources, facilitating the transfer of materials and data, monitoring the progress of projects and reporting their status to customers, and closing out projects by invoicing for services rendered.
? Serving in a financial management role by providing justification for requisitions, working with vendors to obtain optimal pricing, determining and adjusting service fees.
? Supervising, training and directing the day to day activities of research staff.
? Developing and maintaining Standard Operating Procedures.
? Troubleshooting problems associated with equipment, software, experimental design, assays and reagents and deviations from protocol.
? Assisting in the development and maintenance of LIMS and other laboratory-related computer programs.
? Keeping abreast of scientific advances and new technologies and how they may be introduced into the facility.
Qualifications
? PhD Scientist with = 6 years? experience in a field related to genetics or genomics
? Expertise in ?nextgen? sequencing applications including those from Illumina, 10X Genomics and/or Pacific BioSciences.
? Demonstrated project management experience.
? Excellent skills in experimental design, implementation, troubleshooting, and data analysis.
? Experience managing large datasets and interacting with databases and software tools.
? Experience supervising technical staff.
? Detail-oriented and organized, with strong initiative and sense of ownership when driving projects to completion.
? Excellent verbal and written communication skills.

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Postdoc RNA epigentics

Date Posted:
3/6/2017

UNC

NC

Postdoctoral Position in RNA Epigenomics
A postdoctoral position is available in the laboratory of Dr. Gregory Matera in the Integrative Program for Biological and Genome Sciences, University of North Carolina at Chapel Hill.

The Program is devoted to model-organism biology and it provides a highly collaborative environment, along with exceptional interdisciplinary opportunities for trainees. The Matera lab has broad interests in basic molecular mechanisms that regulate RNA processing and RNP assembly in vivo. Using Drosophila as our primary genetic system, we engineer BAC-based histone gene clusters to express specific histone mutants that prevent binding of effector proteins in chromatin. These studies will thus directly evaluate the contributions of specific histone PTMs to epigenetic regulation during development and neoplasia.

Additional Information:
McKay D.J., Klusza S., Meers M.P., Penke T.J.R., Curry K.P., McDaniel S.L., Malek P.Y, Cooper S.W., Tatomer D.C., Lieb J.D., Strahl B.D., Duronio R.J. and Matera A.G. (2015). Interrogating the function of metazoan histones using engineered gene clusters. Developmental Cell 32: 373-386. PMCID: PMC4385256
Penke T.J.R., McKay D.J., Strahl B.D., Matera A.G. and Duronio R.J. (2016). Replication-dependent H3K9 is essential for formation of pericentromeric heterochromatin and transposon silencing, but not for completion of Drosophila development. Genes & Development 30: 1866-1880. PMID: 27566777
Meers M.P., Henriques T., Lavender C.J., McKay D.J., Strahl B.D., Duronio R.J., Adelman K. and Matera A.G. (2016). Histone gene replacement reveals a post-transcriptional role for H3K36 in maintaining metazoan transcriptome fidelity. eLife (in revision).

Qualifications:

Qualifications:
We are looking for enthusiastic, highly motivated and creative individuals with a strong interest in epigenetics and chromatin biology. US Citizens and permanent residents can apply for initial funding through the UNC Lineberger Comprehensive Cancer Center. Successful candidates for this position are expected to have a PhD in the biological sciences, along with demonstrated experience in molecular genetics and genomics and/or Drosophila.

Website:

http://labs.bio.unc.edu/Matera/MateraLab/Homepage.html

To Apply:

Contact:
Applicants should send a single PDF file containing a cover letter, curriculum vitae, and a short (1-2 pg) summary of their previous research experience and future goals. CV should include contact information for three references. Send to Greg Matera: matera@unc.edu


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Postdoc Biochemistry and Gene Expression

Date Posted:
3/6/2017

NIEHS

NC

Postdoctoral Position in Biochemistry and Gene Expression

A postdoctoral fellow position is available in the Eukaryotic Transcriptional Regulation group, Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences. Our research program studies regulation of gene expression through chromatin mediated mechanisms, focusing on histone modification and chromatin remodeling (see for example Takaku et al., 2016 Genome Biology 17: 36 doi: 10.1186/s13059-016-0897-0; Li et al., 2015 Cell Metabolism 19: 702-711).. Current work addresses gene regulatory paradigms focusing on the Mi-2/NuRD complex and on DNA methylation. Successful candidates will lead projects that incorporate state of the art technologies, including epigenomics and biochemistry in cellular and animal models.

The National Institute of Environmental Health Sciences (NIEHS) is located in Research Triangle Park, North Carolina.

The NIH is dedicated to building a diverse community in its training and employment programs.

Qualifications:

We seek highly motivated individuals with an MD degree or a PhD degree in Biology, Molecular Biology, Biochemistry or a related discipline with less than 2 years postdoctoral experience. Experience in protein biochemistry or molecular biology is highly desirable. Recent graduates are encouraged to apply.

To Apply:

For consideration, send cover letter, curriculum vitae including list of publications, and the names/phone numbers/email addresses of three references to:

Dr. Paul Wade
National Institute of Environmental Health Science
Epigenetics and Stem Cell Laboratory
Room D414, MD D4-04
111 Alexander Drive
Research Triangle Park, NC 27709
E-mail: wadep2@niehs.nih.gov

 


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Assistant Professor Biochemistry

Date Posted:
3/6/2017

Campbell University

NC

Assistant/Associate Professor
Biochemistry
Department of Pharmaceutical Sciences
Campbell University College of Pharmacy & Health Sciences

The Department of Pharmaceutical Sciences invites applications for a 12-month, tenure track position at the assistant or associate professor rank available in May 2017.  The primary responsibilities of the successful candidate will be to teach in Bachelors & Masters of Science in Pharmaceutical Sciences and the Doctor of Pharmacy (PharmD) programs, and serve as part of a multidisciplinary teaching team in undergraduate and graduate courses in pharmaceutical sciences. The Doctor of Pharmacy Program will use an integrated curriculum model starting fall 2017. Preference will be given to candidates with expertise in teaching and research in protein chemistry, clinical biochemistry, metabolic diseases, or biotechnology. The successful candidate will establish a research program in his/her area of interest that incorporates undergraduate and graduate research training. The College of Pharmacy & Health Sciences offers other degree programs for BS or MS in Clinical Research, BS in Nursing, MS in Public Health, Master of Physician Assistant Practice, and a Doctor of Physical Therapy. Campbell University is a private Christian university located thirty-five miles south of RTP in central North Carolina. Its student-oriented focus and proximity to RTP facilitate excellent academic and professional interactions.

Qualifications:

Candidates for this position must have a PhD or equivalent terminal degree in Chemistry, Biological or Biomedical Sciences with emphasis in biochemistry and cell biology. Noteworthy teaching and postdoctoral research experience are strongly recommended and a background in pharmacy education is desirable, but not required.

To Apply:

Interested applicants should apply online at http://www.campbell.edu/about/employment/ including a letter of intent, statement of teaching philosophy, statement of research interests, curriculum vitae, and the names and addresses of three references. Review of applications will begin immediately and continue until the position is filled.


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Postdoc Novel covalent inhibition oncology chemistry

Date Posted:
3/6/2017

AstraZeneca

MA

At AstraZeneca, we believe in the potential of people who share our passion for science. By thinking boldly and working collaboratively to pursue discoveries beyond imagination, you’ll develop further and faster than you thought possible. We’ll complement your drive and determination to meet unmet patient needs around the world with the inspiration and opportunities to enhance your niche expertise and build your skills. So if you’re curious about what science can do, come and make a difference.  

Cancer is one of the greatest challenges facing medical science today. In our Oncology Team, you’ll push the boundaries of science every day to overcome that challenge. We’ve been at the centre of some of the biggest breakthroughs in oncology. In lung cancer, for example, we‘ve brought together complementary expertise to aid discovery and accelerate development in new medicines through a variety of partnerships and initiatives. We’re also early adopters of new technologies to support innovation, including CRISPR, genome editing techniques and a next-generation sequencing platform for companion diagnostics in oncology. But we’re not stopping there. With a world-class pipeline and some of the best experts in the industry, we’re in a great position to develop even more innovative therapeutic approaches.

   Main duties and responsibilities  

 

   PostDoc long title: Investigation of covalent inhibitors targeting non-catalytic lysines in disease-causing proteins
 

 

   A self-motivated chemist, you’ll work in a multidisciplinary setting carrying out cutting-edge research in rational design of covalent inhibitors targeting non-catalytic lysines. You will be responsible for designing and synthesizing covalent inhibitors towards disease causing proteins; investigating the properties of the resulting inhibitors; applying the learning in the drug discovery program; and communicating scientific finding in the internal/external science community.  

Requirements

   Essential requirements  

 

       
  •      PhD in organic chemistry or chemical biology    
  •    
  •      Strong synthetic and analytical skills    
  •    
  •      Basic understanding in medicinal chemistry    
  •    
  •      Ability to operate effectively in a multidisciplinary environment    
  •    
  •      Strong track record in recent peer-reviewed publications and external presentations    
  •    
  •      Excellent oral and written communication capabilities.    
  •  

   Desirable requirements  

 

       
  •      Experience in protein production/purification and/or running a biological test    
  •    
  •      Knowledge of DMPK    
  •  

 

To apply for this position, please click the apply link below.

   AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised  

   This is a 2 year Fixed Term Contract opportunity, plus 1 year which will be merit based. The role will be based at Boston, MA with a competitive salary on offer

Opening date of advert: 17th February 2017

 

Closing date of advert:  18th April 2017

   If you share our passion for scientific excellence, find out more atcareers.astrazeneca.com  

 


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Postdoc Mechanistics of resistance to BH3 mimetics in cancer

Date Posted:
3/6/2017

AstraZeneca

MA

At AstraZeneca, we believe in the potential of people who share our passion for science. By thinking boldly and working collaboratively to pursue discoveries beyond imagination, you’ll develop further and faster than you thought possible. We’ll complement your drive and determination to meet unmet patient needs around the world with the inspiration and opportunities to enhance your niche expertise and build your skills. So if you’re curious about what science can do, come and make a difference.  

Cancer is one of the greatest challenges facing medical science today. In our Oncology Team, you’ll push the boundaries of science every day to overcome that challenge. We’ve been at the centre of some of the biggest breakthroughs in oncology. In lung cancer, for example, we‘ve brought together complementary expertise to aid discovery and accelerate development in new medicines through a variety of partnerships and initiatives. We’re also early adopters of new technologies to support innovation, including gene editing, genome editing techniques and a next-generation sequencing platform for companion diagnostics in oncology. But we’re not stopping there. With a world-class pipeline and some of the best experts in the industry, we’re in a great position to develop even more innovative therapeutic approaches.

   Main duties and responsibilities  

 

   PostDoc long title:Understanding mechanisms of innate and acquired resistance to BH3 mimetics and optimization of their therapeutic use in cancer

 

   BH3 mimetics, such as the recently approved Bcl2-selective inhibitor ventoclax, are promising anti-cancer agents that are showing encouraging clinical activity. Part of a multidisciplinary Oncology drug discovery team focused on bringing new medicines to cancer patients, you’ll help develop a better understanding of why some cancers are sensitive to BH3 mimetics while others are not, and applying that understanding to optimise the therapeutic benefit of this promising new class of anti-cancer agents.  

   Your objectives will be to develop a molecular understanding of why BH3 mimetics induce apoptosis in some tumor cells but not in others, and identify clinically-actionable biomarkers that accurately predict sensitivity to BH3 mimetics. This will involve identifying a panel of cell lines across haematological and solid cancer types, with a range of sensitivities to individual BH3 mimetics, and evaluating the Bcl2 family member status across the cell panel. Your role will also entail pharmacologically and genetically manipulating the cell lines to identify molecular dependencies, as well as identifying targeted therapies that when combined with individual BH3 mimetics reverse innate resistance to BH3 mimetics.  

   Opportunities and training will be provided to develop both in vitro and in vivo models of resistance to selective BH3 mimetics. Access to state-of-the art genetic, molecular and proteomic platforms for characterisation and genetic and chemical tools to validate mechanisms and identify approaches to overcome resistance will also be available.  

Requirements

   Essential requirements  

 

       
  •      PhD and/or MD in relevant area of biology    
  •    
  •      Strong desire to learn and perform cancer research in an industry setting    
  •    
  •      Strong scientific background in cell biology, preferably cancer    
  •    
  •      Experience with design and execution of in vitro and/or in vivo experiments to determine the effects of therapeutics on biological systems    
  •    
  •      Experience with a variety of laboratory techniques including cell culture, compound handling, western blotting, RTPCR and proliferation/viability assays    
  •    
  •      Highly motivated, innovative and reliable with the ability to effectively problem solve    
  •    
  •      Flexible, collaborative and team-oriented mindset    
  •    
  •      Strong publication track record    
  •    
  •      Effective communication and presentation skills.    
  •  

   Desirable requirements  

 

       
  •      Strong scientific background in Bcl2 family biology and familiarity with the mechanism of action of BH3 mimetics    
  •    
  •      Prior experience in understanding resistance mechanisms to oncology drugs    
  •    
  •      Additional technical skills including apoptotis assays, flow cytometry, siRNA-based gene silencing, gene editing based gene deletion, NGS sequencing, and proteomic profiling.    
  •  

   To apply for this position, please click the apply link below  

   AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.  

   This is a 2-year, fixed-term contract opportunity, plus 1 year which will be merit based. The role will be based in Altham, MA, USA, with a competitive salary on offer.  

Opening date of advert: 17th February 2017

 

Closing date of advert:  18th April 2017

   If you share our passion for scientific excellence, find out more atcareers.astrazeneca.com  

 


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Postdoc Unravelling oncotherapy stem cell toxicity

Date Posted:
3/6/2017

AstraZeneca

MA

 At AstraZeneca, we believe in the potential of people who share our passion for science. By thinking boldly and working collaboratively to pursue discoveries beyond imagination, you’ll develop further and faster than you thought possible. We’ll complement your drive and determination to meet unmet patient needs around the world with the inspiration and opportunities to enhance your niche expertise and build your skills. So if you’re curious about what science can do, come and make a difference.  

   Drug Safety and Metabolism
 

 

One of the greatest challenges when discovering and formulating effective medicines lies in mapping their pharmacokinetic properties – how they’ll react within the human body. You’ll ensure our drug products are safe for clinical trials, and ultimately safe to deliver as novel treatments to patients. To make that happen, you’ll be working with truly cutting-edge in silico, in vivo, cellular and molecular technologies to push the boundaries of predictive science.

   Main duties and responsibilities  

 

   PostDoc long title: Unravelling the stem cell biological mechanisms underpinning the toxicity that limits efficacy for oncology therapeutics  

 

You’ll have the opportunity to identify the untowardmechanisms by which oncotherapeutics affect adult stem cells, progenitor cells, and differentiating enterocytes. Your work will utilize cutting-edge molecular and cellular biology techniques to dissect essential elements of stem cell
self-renewal and maturation in the intestine. In addition to uncovering as of yet undiscovered frontiers in stem cell biology, you’ll directly contribute to understanding the dose-limiting toxicities that will make, or break, an entirely new class ofoncotherapeutics.  

   Key tasks will be to define intestinal stem cell and differentiating enterocyte populations using in vitro, in vivo, and in silico methodologies and quantify their sensitivity to various pharmacological agents. and You will use bioinformatics to identify key transcriptional regulators of intestinal stem cell self-renewal and proliferation. You’ll test the essentiality of the identified genes in cutting-edge organoid systems and identify their key downstream targets, and verify your findingsin vivo
using transgenic animal systems.  

   We’ll encourage you to publish your findings in high-impact, peer-reviewed scientific journals. Working collaboratively with experts internally and externally across various disciplines you’ll also present results externally at scientific conferences and meetings.

Requirements

   Essential requirements  

 
       
  •      PhD and/or MD in relevant discipline, such as molecular biology, physiology, pharmacology or toxicology    
  •    
  •      Expertise with standard molecular biology techniques, including mammalian cell culture    
  •    
  •      Proven scientific track record of publications in reputable scientific journals    
  •    
  •      Commitment to medical sciences.    
  •  

   Desirable requirements  

 
       
  •      Previous experience with culturing stem cells and/ororganoid systems
  •    
  •      Bioinformatics expertise    
  •    
  •      Previous experience with culturing stem cells and/or organoid systems    
  •    
  •      Experience working with lab animals    
  •    
  •      Knowledge of cell signalling pathways.    
  •  

   To apply for this position, please click the apply link below  

   AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.  

   This is a 2 year Fixed Term Contract opportunity, plus 1 year which will be merit based. The role will be based at Boston, MA, US with a competitive salary on offer

Opening date of advert: 17th February 2017

 

Closing date of advert:  18th April 2017

   If you share our passion for scientific excellence, find out more atcareers.astrazeneca.com  

Apply

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Postdoctoral Fellow Gene Delivery

Date Posted:
3/6/2017

Medimmune

MD

 If you’re inspired by the possibilities of science to change lives and you thrive when making brave decisions – join us.  

 

   MedImmune is the worldwide biologics research and development arm of AstraZeneca. Here, you’ll have the opportunity to make a difference in people’s lives every day. As one of the world’s premier biotechnology companies, our mission is centered on delivering life-changing products that advance world health, and help fight and cure disease.  As a Postdoctoral Fellow in Gaithersburg MD, you’ll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients’ lives.  

 

   We’re constantly pushing the boundaries of science to deliver life-changing medicines to patients, with a passion for discovery and a pipeline to show for it. We’re pioneering innovative research and exploring novel pathways across key therapeutic areas including oncology, respiratory, inflammation and autoimmunity, cardiovascular and metabolic disease, and infection and vaccines. And we’re industry-leading in immunology, protein engineering and translational science. We offer a unique and strong collaborative network as part of the AstraZeneca family, as together we explore synergies between small and large molecules.  

 

   MedImmune has a dynamic environment that fosters collaboration and innovation. We attract top minds, and we nurture and build top talent.  

     Position Summary    

   The Department of Antibody Discovery and Protein Engineering seeks a highly motivated and broadly skilled Postdoctoral Fellow. You will be working in a fast-paced multidisciplinary matrix environment to conduct research towards development of non-viral gene delivery systems.  

 

   Main Duties and Responsibilities  

 

   The main duties for this position are to produce and characterize materials that enable efficient delivery of DNA into target cells. Furthermore, you will assess the efficiency of DNA delivery systems towards expression of therapeutically important molecules in vitro and in vivo. You will be working in a fast-paced multidisciplinary matrix environment to conduct research at the interface of materials science, chemistry, and biology - harmonizing these disciplines to enable effective gene delivery technologies.  

 

   Essential requirements  

 

       
  •      A strong background in materials science, polymers, bioconjugation and subcellular trafficking of macromolecules.    
  •    
  •      Demonstrated proficiency with formulating and characterizing DNA-polymer complexes.    
  •    
  •      In-depth knowledge of biological barriers associated with gene delivery and strategies to overcome these barriers.    
  •    
  •      Proven ability to translate desired physical properties into the molecular design of polymers.    
  •    
  •      Proficiency with polymer synthesis and polymer modification reactions.    
  •    
  •      Hands-on technical proficiency with macromolecule characterization using modern chromatography methods, NMR, and mass spectrometry.    
  •    
  •      Technical proficiency with nanoparticle formation and characterization by light scattering methods.    
  •    
  •      Proven ability to work efficiently and productively in a highly dynamic team environment.    
  •    
  •      Ability to successfully drive research projects to completion and communicate results as evidenced by a strong publication record.    
  •    
  •      Must be able to multi-task and manage multiple projects simultaneously.    
  •    
  •      Strong motivation, attention to detail, ability to think independently, and strong problem-solving skills.    
  •    
  •      Demonstrate strong communication, interpersonal, and organizational skills.    
  •  

 

Requirements

   Education/Experience  

 

   Ph.D. degree in Materials Science, Bioengineering, Chemistry, Polymer Science, Biomedical Engineering, Materials Engineering or related field.  

 

   0-1 years of related experience in academic setting  

 

   Desirable Requirements  

 

       
  •      Hands-on experience using a ZetaSizer Nano instrument.    
  •    
  •      Previous experience using microfluidics.    
  •    
  •      Knowledge of in vitro methods to assess DNA transfection efficiency.    
  •    
  •      In vivo experience is a strong plus.    
  •  

 

   Next Steps – Apply today!  

 

   To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity.  If you know someone who would be a great fit, please share this posting with them.  

 

   AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law.  AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.  

 


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Volunteer Philadelphia Science Festival

Date Posted:
3/6/2017

Franklin Institute

PA

Job description

The Franklin Institute is a non-profit science and technology museum.

 

The 7th Annual Philadelphia Science Festival is scheduled from April 21-29, 2017.

 

This community-wide celebration of science features lectures, debates, hands-on activities, special exhibitions and a variety of other informal science education experiences for all ages, the Festival aims to provide opportunities for all Philadelphians to positively engage with and build a community around science, engineering, and technology.

 

Without the help of individual volunteers, it would be impossible to pull off a nine-day Festival with over 90 events. From helping with event evaluations to running hands-on activities to assisting with set-up and clean-up, volunteers play a crucial role in Festival operations. We need people who are willing to donate their time, energy, enthusiasm and expertise to our science celebration.

 

Volunteers will be needed at various locations throughout the Greater Philadelphia area.

 

This is a volunteer opportunity provided by VolunteerMatch, in partnership with LinkedIn for Good.

 

Desired Skills and Experience

This position requires the following skills: People Skills


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Scientist Image Analyst

Date Posted:
3/6/2017

Allen Institute for Cell Science

WA

ob description

The goal of the Allen Institute for Cell Science is to advance understanding of cell behavior in its normal, pathological, and regenerative contexts. The Institute, located in Seattle, Washington, employs a multi-disciplinary team approach to generate novel cellular reagents, models, and databases that are informed by and open to the community. The Institute aims to understand cells, individually and in collectives, as an integrated system of organelles, molecular machines, and regulatory complexes that are repurposed and specialized to generate the plethora of observed cellular behaviors. It will do this using human induced pluripotent stem cells (hiPSCs), gene editing, and live cell imaging, developing predictive models and theory, and creating a novel multi-scale, dynamic and visual output for the experiments and models.

 

 

 

Position Summary

The goal of the Image-based Assay Development team is to develop and implement a pipeline of image-based assays of cell organization, activity, and function. This Scientist level position is part of a team that develops image-based assays of cellular organization and activities that are amenable to scale-up and integration into a live-cell high-throughput microscopy pipeline. The focus of this position is on image processing, feature extraction, and image analysis activities. S/he may be required to supervise the activities of others and will work collaboratively with the Institute’s technical and programmatic teams.

 

 

 

Job Responsibilities

  • Develop and implement robust image processing pipelines, algorithms, feature extraction, and protocols for reproducible image-based assays of cell organization, dynamics, activities, and function
  • Collaborate with other teams in the institute to scale-up image processing protocols into a high throughput microscopy pipeline
  • Maintain rigorous quality control standards
  • Maintain meticulous records and work closely with other scientists to coordinate complex experiments
  • Adherence to SOPs, GLPs and regulatory requirements
  • Contribute to the implementation of an image management system
  • Coordinate with other programs in the Institute to ensure seamless integration and sharing of resources and data
  • Prepare written summaries and present activities internally and publicly

 

Basic Qualifications

  • PhD in a biological science (e.g. cell biology, biophysics, bioengineering), physical science, or related science or engineering field
  • Extensive experience in image processing and analysis
  • Experience in image-based cell biology assays; some experimental experience would be an advantage
  • Experience in 3D image processing and segmentation preferred
  • Experience with machine learning approaches would be an advantage
  • Experience in a range of light microscopy modalities (especially 3D confocal and spinning disk microscopes) would be an advantage
  • Careful attention to detail and excellent interpersonal skills

     

  • Experience working in a multi-disciplinary environment in academic or industrial settings
  • Ability to work independently and in a collaborative, multidisciplinary environment

 

Communication Skills

Ability to read, analyze, and interpret general business periodicals, professional journals, technical procedures/reports/documents, or governmental regulations. Ability to write reports and business correspondence and speak effectively in front of groups of employees and external populations.

 

Reasoning and/or critical thinking ability

The ability to define problems, collect data, establish facts, and draw valid conclusions. Ability to interpret an extensive variety of technical instruction. Constructive thinking and alternative short- to long-term solutions must be considered. Action plans must be developed and implemented.

 

Computer Skills

Advanced ability to operate computers and related software programs. Strong computer programming skills. Knowledge of Python would be an advantage.

 

 

 

 

PHYSICAL REQUIREMENTS AND WORK ENVIRONMENT

 

Chance of exposure to potentially hazardous conditions that may result in the threat of health and safety including extreme noise, or temperature changes, climbing and lifting, chemicals and other hazardous materials, and machinery.

Seniority Level

Mid-Senior level

Industry

  • Biotechnology
  • Research

Employment Type

Full-time

Job Functions

  • Science
  • Research

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Senior Editor Grant Writer Human Oncology

Date Posted:
3/6/2017

Memorial Sloan Kettering

NY

Job description

Company Overview

 

At Memorial Sloan Kettering (MSK), we’re not only changing the way we treat cancer, but also the way the world thinks about it. By working together and pushing forward with innovation and discovery, we’re driving excellence and improving outcomes.

 

For the 27th year, MSK has been named a top hospital for cancer by U.S. News & World Report. We are proud to be on Becker’s Healthcare list as one of the 150 Great Places to Work in Healthcare in 2016, as well as Glassdoor’s annual Employees’ Choice Awards 2017. We’re treating cancer, one patient at a time. Join us and make a difference every day.

 

Job Description

 

The Human Oncology and Pathogenesis Program (HOPP) was founded by Dr. Charles Sawyers in 2006 to address the challenges presented by cancer research in the era of targeted therapies. By bringing together researchers in many disciplines, HOPP’s goal is to advance scientific knowledge while bridging discoveries made in the laboratory with those made in the clinic. The department has grown to a faculty of nearly 20 physician-scientists, each with independent laboratories and research aims, and approximately 300 research and administrative staff.

 

HOPP’s administrative team partners with Dr. Sawyers and the HOPP Faculty to provide operational, financial and administrative support to facilitate the effective functioning of their research and academic efforts.

 

This newly created Senior Editor/Grant Writer position would directly support the administrative, academic, and grant related editorial needs of Dr. Sawyers as well as work collectively with other members of the administrative team to support the pre-award and grants management activities of the department. The incumbent will enhance the faculty members’ grant applications and academic efforts through a combination of editing, grant coordination, and project management.

 

As a Senior Editor/Grant Writer You Will

 

  • Edit, write, and coordinate/project manage academic, research, and grant-related documents to support the office of the Chair as well as his research portfolio
  • Partner with other senior faculty to provide program management for larger, program and collaborative grants, both during the application phase and throughout the life of the grant
  • Provide support with grant preparation and work with investigators and other staff to ensure timely submission of proposals so as to maximize external funding for the research portfolio across the department

     

You Are

 

  • Capable of building strong customer relationships and delivering customer-centric solutions
  • Flexible in your approach and demeanor in order to align with the shifting demands of evolving circumstances
  • An effective communicator, capable of determining how best to reach different audiences and executing communications based on that understanding
  • A selfless team-player, eager to work in a collaborative, fast-paced environment
  • A dedicated administrative professional, accountable for your work, and invested in MSK’s mission

     

You Have

 

  • A minimum of a Bachelors degree plus 5-7 years of grant submission/project-coordination experience OR a Masters degree or PhD in a life science plus 3-5 years of publishing, editing, or managing experience
  • Experience in substantive editing, stylistic editing, and copy editing required. Experience in developmental and plain-language editing preferred
  • Research or medical editing experience preferred, to include knowledge of: research, medical, and grant related terminology; technical publishing; grammar, syntax, and usage; new media, print, and web-based writing processes
  • American Medical Writers Association Board of Editors in the Life Science University of Chicago Medical Writing & Editing Program preferred.
  • Ability to understand and communicate complex information
  • Ability to organize electronic and print data materials.
  • Proficiency in Word and bibliographic/reference management software (i.e., EndNote) required. Knowledge of Excel, PowerPoint, Adobe Acrobat Writer, Quark Express or InDesign, Photoshop, and Illustrator preferred.

     

Closing

 

MSK is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision.

 

Federal law requires employers to provide reasonable accommodation to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job. Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment.


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Science Writer

Date Posted:
3/6/2017

RA Capital

MA

The Science Writer will be responsible for writing and editing original content that supports RA Capital’s mission to openly contribute our knowledge and understanding of the biotechnology industry: to share our perspective on the future of life science technology, global healthcare and cost-effective medicine, drug-development game theory, clinical trial design, business models, and other best practices.

 

 

 

Key Accountabilities:

 

 

  • Writes and edits technical content that reflects RA Capital’s intellectual rigor, professional standards, and drive toward innovation

     

  • Stays current with science and business trends, particularly in the biotech space, and can speak to how they influence each other

     

  • Has a critical and detail-oriented approach toward ideas and content. Expands on and improves the internal content generated by the RA Capital team

     

  • Generates engaging and impactful external communications

     

  • Works collaboratively across internal teams

     

 

 

 

Technical & Behavioral Skills:

 

 

 

  •  

    Excellent scientific writing and editing capabilities

  •  

    Proven track record in biotech or medical writing for articles, white papers, web content, or other externally facing documents

  •  

    Basic understanding of investment principles and strategies

  •  

    Ability to adapt content generated by the RA Capital team for various audiences while retaining the original voice and intent

  •  

    Possesses rational convictions while being intellectually curious and open-minded nature with a humility toward learning

 

 

 

  • Seeks out innovative solutions to complex problems

  •  

    Excellent interpersonal communication and teamwork skills

  •  

    Ability to work independently, both under supervision and as a contributing team member

  •  

    Ability to clearly and concisely articulate ideas and opinions

 

 

 

  • Ability to rapidly learn and apply new writing styles and standards

  • Balances exceptional attention to detail with a sense of urgency

     

 

 

Education:

 

  • Advanced degree in a life sciences field required

     

 

Minimum Work Experience:

 

  • 3-5 years professional experience in and around the medical, biotechnology, or pharma environment

     

  • 2-3 years experience writing, editing, and promoting original content

     

  • Experience with deadline-driven projects and ability to reprioritize as needed

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Science Writer and Public Relations Specialist

Date Posted:
3/6/2017

Gladstone

CA

The Gladstone Institutes is an independent, not-for-profit research institution affiliated with the University of California San Francisco (UCSF), contributing to the health and well-being of all people through medical research, education, and outreach in the areas of heart disease, HIV/AIDS, and neurological disease. Gladstone is composed of three separate institutes and approximately 500 employees. Our employees receive exceptional benefits. We are located in an award-winning building adjacent to UCSF's Mission Bay Campus. Gladstone has consistently ranked as one of the top places to work in academia in the United States.

 

 

 

Under the direction of the VP of Communications, the Science Writer and Public Relations Specialist will write compelling content for a variety of audiences based on Gladstone's basic and translational science. The Specialist will design, coordinate, and execute a robust media-relations strategy that aligns with Gladstone's strategic communications plan.

 

 

 

General

 

 

    • Establish strong working relationships with Gladstone scientists to facilitate communicating their research findings

 

    • Conduct interviews with faculty and trainees to develop stories

 

    • Ensure content standards and scientific accuracy of all content produced

 

    • Maintain an editorial content calendar

 

    • Ensure brand voice is handled appropriately and consistently

 

 

Media Relations

 

 

    • Write and distribute press releases that support scientific publications and grants, ensuring the content is designed for a lay audience

 

    • Build and maintain relationships with local, state, and national media, and track the needs/interests of the audiences to whom they communicate

 

    • Establish appropriate editorial processes to ensure appropriate stakeholders are heard and served

 

    • Identify creative public relations opportunities and develop appropriate communication materials that support Gladstone's communication plans

 

    • Develop, targeted, engaging, and effective pitches aligned with media strategy to place with media, speaking engagements, and other activities

 

    • Coordinate the appropriate Gladstone spokesperson to respond to media opportunities, and serve as Gladstone's primary point-of-contact for local, state, and national media requests

 

 

Writing and Storytelling

 

 

    • Ability to transform highly technical scientific content into press releases, stories, op-eds, ghost-written articles, research articles, lay-science pieces, and other content as needed

 

    • Work with VP of Communications and VP of Philanthropy to develop stories for online articles

 

    • Managing editor of two monthly e-newsletters, one geared toward scientists and another toward the general public, which includes current donors and seeks to cultivate prospective donors

 

    • Ability to appropriately gauge content and story ideas for differing audiences

 

 

New Media Activities

 

 

    • Enter content into the news portion of the Gladstone website

 

    • Knowledge of social media tools and trends

 

    • Maintain metrics and create tracking reports as needed and communicate impact of various media-relations activities to VPs and President

 

    • Liaise with team members for creative assets

 

    • Coordinate video and photography shoots

 

    • Curate Brand Publishing campaigns to elevate Gladstone's visibility

 

    • Advise social media campaigns and promotions

 

 

 

 

Education and Experience

 

 

    • Bachelor's Degree requires; advanced degree in sciences (PhD or MD) preferred

 

    • 3+ years experience writing and editing scientific content for a variety of audiences

 

 

Knowledge and Skills

 

 

    • Uniquely skilled at translating complex scientific research into engaging and informative content; experience creating content for donors and prospective donors a plus

 

    • Knowledge of science journalism landscape;established relationships with top-tier science writers and media contacts

 

    • Flexibility and success in meeting the needs of diverse individuals and groups

 

    • Outstanding attention to detail

 

    • Ability to work under deadline, to set and maintain priorities, and to manage a variety of projects simultaneously in a fast-paced environment

 

    • Ability to juggle continuously changing priorities

 

    • Outstanding interpersonal skills, including the ability to work closely with others in refining programs and policies

 

    • Working knowledge of HTML

 

  • Familiarity with best practices in Search Engine Optimization

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Science and Technology Writer

Date Posted:
3/6/2017

Berkeley Lab

CA

Job description

Position Summary:

Berkeley Lab’s Accelerator Technology and Applied Physics Division (ATAP) is seeking a Science Writer/Editor who can reach a wide range of audiences both accurately and engagingly in a variety of media. We are looking for someone with experience and expertise in a broad range of communications, who has excellent proofreading skills and who knows how to tell a good story.

 

Embedded in a diverse R&D division at the leading edge of multiple fields, you’ll work with Divisional management, as well as scientists and engineers, with the support of central graphic-arts and Web-design resources. The result: eye-catching, reader-engaging products that convey not only the facts, but also the importance and excitement, of how ATAP meets the needs of the scientific community and the nation as part of the Department of Energy research complex.

 

Initiative, creativity, and a view of the whole of communication—not just writing but also graphics, choice of medium, and selection of channels that reach the right audience at the right time, as well as the information life cycle—are key skills. Other important aspects include editing to ensure professional results; reconciling multiple inputs and review comments; and coordinating with overall projects and other stakeholders. This position will be filled at level 2 or 3, dependent on experience.

 

Your Role:

  • Communicate complex scientific information understandably, accurately, and engagingly to fellow researchers, funding agencies, and the public.

    • Write, edit, and deploy an online outreach newsletter.

    • Create and maintain Divisional and scientific-program websites.

    • Support Berkeley Lab Public Affairs in developing stories about newsworthy subjects and responding to media inquiries.

  • Work with staff and managers to identify, develop, research and produce timely and effective communications tailored for various audiences.

  • Gather information from multiple sources to write and edit high-profile documents such as science news articles and special reports.

  • Complete complex and demanding publication projects with minimal direction based on project objectives.

  • Consult on and assist with managerial and scientific presentations.

  • Respond to other operational information needs.

 

What Is Required:

  • Bachelor’s degree or higher, preferably with an emphasis in both journalism/communication and science or engineering, plus 5 years of professional experience in writing, editing, layout, and production of science and technology material.

  • Excellent writing skills, as demonstrated by a portfolio of publications with technical content (at least some in a journalistic style) and by recommendations.

  • A questing mind combined with strong interest in the physical sciences.

  • Experience in writing in a professional environment, including review and approval cycles, schedules, and deadlines.

  • Working knowledge of electronic and print publishing and design.

  • Strong interpersonal communication skills.

  • Demonstrated ability to work successfully as a member of a team of individuals in which cooperation and interaction are implicit in the work.

Job posted by

Mohammad Rasool Yousufzai

Recruiter at Lawrence Berkeley National Lab

Job Poster Location

Berkeley, California

Premium

Seniority Level

Associate

Industry

  • Research

Employment Type

Full-time

Job Functions

  • Writing/Editing
  • Science

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Senior Scientific Editor

Date Posted:
3/6/2017

D. E. Shaw Research

NY

Job description

Individual with extraordinary communication skills sought for position as a Senior Scientific Editor at a New York City-based scientific research group that aims to make groundbreaking contributions within the fields of biology, chemistry, and drug discovery.

 

This hire will work closely with a team of world-class scientists and engineers on the preparation and writing of scientific manuscripts, primarily in the area of computational chemistry, structural biology, software, and hardware for biomolecular simulations. Responsibilities will include coordinating (and contributing to) the writing and editing of manuscripts, corresponding with journals, and working with the group’s senior members to communicate both particular research results and the lab’s long-term scientific mission. This is a high-visibility role that affords the opportunity to help shape our high-impact papers.

 

 

Ideal candidates should have an exceptional record of academic accomplishments, a Ph.D. in chemistry, biology, physics, applied math, computer science or a similar field, and experience editing and shaping scientific publications. They should also be outstanding critical thinkers with meticulous attention to detailand strong project management skills. Familiarity with computation and some knowledge of molecular biophysics would be an advantage.

 

 

We are prepared to offer a six-figure salary to candidates of truly exceptional ability.

 

To submit an application, please use the link provided below:

http://www.deshawresearch.com/recruit/jobs/Ads/LinkedIn/SSE

 

D. E. Shaw Research is an independent research group that is pursuing an ambitious, long-term strategy aimed at fundamentally transforming the process of drug discovery. We have developed a special-purpose supercomputer capable of executing molecular dynamics (MD) simulations orders of magnitude faster than was previously possible. Our current projects include investigations of proteins and other biomedically relevant macromolecules as well as the development of computational chemistry methods to enable more accurate and effective MD simulations.

 

D. E. Shaw Research is committed to building a diverse team. We offer an intellectually rigorous and stimulating work environment that is also supportive, flexible, and welcoming. We do not discriminate in employment matters on the basis of race, color, gender, age, religion, national origin, sexual orientation, gender identity, disability, pregnancy, marital status, military service eligibility, veteran status, or any other category protected by law.


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Research Support Specialist Aging

Date Posted:
3/6/2017

In Vitro Cell Research

NY

We are seeking a self-motivated scientist with interest and experience in searching and analyzing online resources for scientific literature to support various aspects of our company’s research goals. Sincere interests in and knowledge of human aging, stem cells and personalized and regenerative medicine are also highly desirable. Expert knowledge of and honest interest in life-extension is required (PLEASE READ THE APPLICATION INSTRUCTIONS BELOW).

 

 

The ideal candidate will have the following:

 

 

 

  • MS, PhD, MD, or MD/PhD in a biomedical science (other backgrounds considered)

     

  • Experience in searching and analyzing traditional online resources of scientific information (e.g. PubMed, ResearchGate, etc) and non-traditional (e.g. message boards, blogs, news articles, etc)
  • Experiencing writing clear, concise and accurate reports and summaries of assigned literature topics

     

  • Ability to quickly assimilate and integrate data from various sources into cohesive summaries

     

  • Excellent written and verbal communications skills
  • Ability to work well in small group settings
  • Ability to multi-task in a dynamic work environment
  • Attention to detail and quality record keeping
  • Ability to work in the United States without sponsorship

     

 

 

 

Application Instructions (PLEASE READ CAREFULLY):

 

 

 

 

 

If interested, please apply via this LinkedIn ad and attach your cover letter and CV (merged as one document is fine). Please address the following points in your cover letter:

 

 

1) List and discuss the life-extension/aging forums/books/researchers you read/follow

 

 

2) List and discuss your top 10 anti-aging/life extension interventions (ranked)

 

 

We are interested in people with a real and sincere desire to conquer aging and that have the credentials to prove it. Applications without a cover letter will not be considered.

 

 

Please note: applying using the LinkedIn app from a mobile device often doesn’t attach the CV or cover letter so please make sure your application includes these documents.


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Higher Education Research Experiences

Date Posted:
3/6/2017

ORNL

TN

Become a part of the Higher Education Research Experiences (HERE) Program at Oak Ridge National Laboratory (ORNL)

 

 

 

Opportunities for qualified students, alumni, and faculty to participate in hands-on research in a real-world setting

 

  • Experience innovative research or technical projects at a cutting edge national laboratory and network with prestigious scientists, researchers, engineers, and laboratory staff
  • Collaborate with international experts in fields that interest you
  • Contribute to the U.S. technical prowess that will enhance living standards and set the nation at the top of a global community
  • Assist in finding solutions to pressing scientific and technical problems

 

Highlights of the program

 

  • Open to Undergraduates, Recent-BS and AAS, MS, PhD and Faculty – Appointments are primarily for Science, Engineering, Technology and Mathematics (STEM) majors but all majors can apply
  • Applications are accepted year-round
  • Appointments can start and end at any time during the year based on your availability and the requirements of the ORNL mentor/project
  • Full-time and part-time appointments
  • Minimum GPA - 2.5/4.0
  • U.S. Citizen or Legal Permanent Resident (LPR)
  • Stipend based on academic status
  • Limited travel and housing allowances (if eligible)
  • Professional development activities

 

Visit http://www.orau.org/ornl/hereatornl/ or contact ORNL Science Education Programs at ornledu@orau.org for more information!


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Teaching and Research Fellow

Date Posted:
3/6/2017

Cornell

NY

Job description

Teaching & Research Fellowship

 

Division of Nutritional Sciences

 

Cornell University

 

The Division of Nutrition Sciences is seeking a full-time, year-round, Teaching and Research Fellow with interest in developing skills and experience in university teaching in preparation for an academic career.This position will start on July 1, 2017 and will be for a two-year period.DNS Teaching Fellows devote 65% of their full-time effort to supporting our undergraduate curriculum in the areas of nutrition, physiology, or anatomy (see course descriptions below), 10% of their time to professional development in teaching through the Cornell Center for Teaching Excellence, and 25% of their time to research.

 

NS 3320 Methods in Nutritional Sciences (Fall. 3 credits) - Laboratory introduction to principles and analytical techniques of nutritional research. Emphasizes analytical concepts and skills required to determine nutrient function and nutritional status of individuals. Topics include methods of nutrient, metabolite, and enzyme analysis in body fluids; methods for assessing individual food intake and nutritional status; and methods for assessing the composition of foods.

 

NS 3410 Human Anatomy and Physiology ( Spring. 4 credits). Introduces human anatomy and physiology by detailing the structure and function of the human body and mechanisms used to maintain homeostasis. Emphasis is given to aspects relevant to the nutritional sciences and medicine. Content includes language of anatomy, cells, tissue, integumentary, respiratory, skeletal, muscular, digestive, nervous, cardiovascular, urinary, and reproductive systems. Clinical examples are provided to highlight perturbations and physiology of topics discussed. Evaluation is based on, iclicker-based class interaction, take home case studies, weekly quizzes, and a midterm and final.

 

NS 3420 Human Anatomy and Physiology Laboratory ( Spring. 2 credits) Principles of human anatomy and physiology will be presented using anatomical models, drawings, dissections, and histology as well as interactive assessments of physiological functions and review of clinical case studies. Weekly lecture will provide content connections with NS 3410. Emphasis will be on location, recognition, and description of anatomical structure and relation to function. Content includes human body orientation and language of anatomy, histology, and regulation of various organ systems. Evaluation based on participation, two lab practicums, and lab written assignments.

 

NS 1150 Nutrition, Health, and Society ( Fall. 3 credits) Discusses the facts and fallacies concerning the role that nutrition, exercise, and other health behaviors play in preventing disease, maintaining good health, and maximizing athletic performance. Emphasis is on understanding the biological mechanisms through which good nutrition and regular exercise affect psychological and physical health; and

 

NS 1160 Personalized Concepts and Controversies (Fall. 1 credit) Provides students enrolled in NS 1150 individualized assistance in many skills including using computers to analyze diets, finding and using scientific references, understanding and criticizing scientific articles, and reviewing material presented in lectures. Sections begin meeting during the 2nd week of classes.

 

During the Academic Year (September-May)

 

DNS Teaching Fellows devote 90% of their effort to participating in the delivery of one course each semester.Responsibilities include contributing to course content, holding office hours for enrolled students and responding to student questions through email, grading, delivering occasional lectures, and assisting with electronic course management (i.e. blackboard and tracking of electronic assignments), organizing graduate and undergraduate teaching assistants and overall administration of the course.

 

DNS Teaching Fellows devote 10% of their effort to formal teaching and advising training by participating in DNS advising workshops and programs offered by Cornell’s Center for Teaching Excellence (CTE).The Center is designed to support individuals interested in becoming effective teachers at the college or university level by providing up to eight certificates in various areas of professional development in teaching.Applicants can view these opportunities at https://www.cte.cornell.edu/programs-services/grads-future-educators-tas/index.html

 

During the Summer Months (June-August)

 

In total, 25% of the year’s effort is devoted to research. Research is undertaken during the summer months when Fellows are able to devote full time effort to research projects under the guidance of a faculty researchmentor selected from within DNS.Information about the research interests of DNS faculty can be found by visiting: http://www.human.cornell.edu/DNS/academic/facultyconcen.cfm .

 

Required Qualifications

 

  • Ph.D. – Proof that all Ph.D. requirements have been fulfilled before the start date is required for any postdoc appointment at Cornell University.

     

Required Competencies

 

  • Planning, organization, problem-solving, and coordination;
  • Good public speaking skills;
  • Ability to work as a member of a team and under pressure;
  • Ability to lead and organize teaching teams comprised of graduate and undergraduate students
  • Proficiency using the electronic medium and software packages such as email and internet browsers, Microsoft Office Word Suite, especially Word, Excel and Power Point.

     

Application Requirements

 

The following documents must be uploaded when applying through Academic Jobs Online:

 

  • aCV;
  • a general letter of interest;
  • a teaching statement including the applicants preference for courses they are interested in supporting; and
  • a research statement including the names of 2-3 DNS faculty members the applicant would be interested in working with.
  • In addition applicants must arrange to have 3 letters of recommendation uploaded to Academic Jobs Online.

     

Incomplete applications will not be reviewed.

 

Diversity and Inclusion are a part of Cornell University’s heritage. We are a recognized employer and educator valuing AA/EEO, Protected Veterans, and Individuals with Disabilities.


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Postdoctoral Research Fellow Biological Technologies

Date Posted:
3/6/2017

Genentech

CA

A post-doctoral research fellow position is available in the Biological Technologies group to perform exciting novel research on characterizing a recently identified interaction between mAb domains and its implications for antibody functionality. The candidate will characterize the interactions between Genentech antibodies and Fc receptors (FcRn, FcγR) using a combination of standard biophysical approaches and newly developed methods. Further, the candidate will develop novel methods to measure the interdomain interaction directly. Experimental approaches will include biophysical and affinity chromatography based methods to characterize protein-protein interactions and will involve a high degree of collaboration between multiple disciplines. The project will require cross-functional collaboration between multiple departments at Genentech and with multiple Roche sites in Europe.

 

This is a 2 year position with an option for a 3rd year.

 

Who You Are

 

A Ph.D. in the biological sciences is required. The candidate must have a proven track record for the biophysical characterization of protein-protein interactions and a thorough understanding of antibody structure and functionality as shown by a solid publication record in the field. The candidate will be responsible for presenting data at internal group, department and / or other company meetings as well as various external meetings when appropriate. Finally, the candidate must be highly self-motivated, have excellent organization and communication skills, and be willing to work independently and as a member of a team.

  •  

Who We Are

 

 

A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

 

The next step is yours. To apply today, click on the "Apply online" button below.

 

Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our


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Bioinformatics Computational Biology Fellow

Date Posted:
3/6/2017

Ancestry.com

CA

Ancestry is currently seeking highly motivated, research-savvy interns who can work full-time for 12-16 weeks during Summer 2017. Our summer internships give you the freedom to conduct novel scientific research for impactful business projects that allow you to develop your talents, enjoy mentorship, and experience challenging work.

 

In the field of Genetics and Computational Biology, we’re looking for fresh minds and diverse ideas with an interest in connecting families and technology. Come join a diverse company of enthusiastic, talented, smart, and very passionate people.

 

Internship Project Description

 

We are seeking fellows to join the AncestryDNA genomics R&D team in our San Francisco office to work with a diverse team of computational biologists, statisticians, epidemiologists, and population geneticists in analyzing genomic, pedigree, and other data. We are mounting a major effort to use genomics to shed light on human diversity, origins, relationships, and human health. The successful candidate will join our efforts to develop, test, and apply new algorithms to push genealogy into the genomics era based in part on a database of over 3 million genotypes.

 

This Is What You Will Do….

 

  • You will work with a mentor on the genomics R&D team to scope out and complete an impactful research project.
  • Potential projects include the analysis of genotype and pedigree data, development of novel computational methods, or improvement/optimization of existing algorithms.
  • You will present your work to the team at the end of the internship.

     

Qualifications

 

  • Currently pursuing a graduate degree in computer science, machine learning, bioinformatics, population genetics, statistics, or a related technical field. Outstanding masters or undergraduate candidates will be considered.
  • Strong analytical and problem solving skills
  • Excellent written and verbal communication skills
  • High levels of creativity
  • Independent, with a demonstrated ability to work on a team

     

Skills And Experience

 

  • Outstanding programming and data visualization skills
  • Solid understanding of human genetics and inheritance
  • Machine learning and/or statistics experience desired
  • Previous research experience in bioinformatics or population genetics desired

     

Additional Information

 

Working for Ancestry

 

We’re a cutting-edge tech company with a very human mission—to help every person discover, preserve, and share the story of what led to them. Combining the rich information in family trees and historical records with the genetic details revealed in DNA, we create unique experiences that give people a new understanding of their lives, because connecting all the pieces of our family story can give us the deepest sense of who we are.

 

For more information on what we do and why you would want to work at Ancestry, visit our careers pagewww.workforancestry.com

 

Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability or protected veteran status.

 

I'm interested

Seniority Level

Not Applicable

Industry

  • Computer Software
  • Internet

Employment Type

Full-time

Job Functions

  • Research
  • Analyst
  • Information Technology
 

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Postdoc Metabolism

Date Posted:
3/6/2017

Emulate Inc.

MA

Job description

An exciting postdoctoral opportunity, working with an innovative Organ-on-Chip technology, is

 

available for a highly-motivated individual. The Organ-on-Chip platform combines design,

 

engineering, and biology to create a human microengineered system that recreates human

 

biology and disease in vitro. This position will focus on the Kidney-Chip to characterize

 

biochemical, genetic, epigenetic, and pharmacological determinants for the uptake and transport of monoclonal antibody drugs across various cell types and human tissues. Individuals with demonstrated experience in cellular, molecular, and biochemical techniques such as gene cloning, gene expression assays, epigenetic analysis, protein expression and quantification, advanced cell culture approaches (e.g. live cell imaging, transcytosis assays, induced pluripotent stem cell models, co-cultures), microscopy, immunohistochemistry, and bioinformatics, are strongly encouraged to apply.

 

 

Key Responsibilities:

 

 

  • Act independently to design, lead, and conduct experiments to characterize and evaluate an emerging Organ-on-Chip technology platform centered on assessing drugtransporter interactions
  • Establish collaborations with experts in adjacent scientific fields as needed for successful interpretation of all data
  • Evaluate and translate a complex set of data

     

  • Publish as primary author in peer-reviewed journal articles, abstracts, and/or patents

     

  • Communicate problems, ideas and suggestions

     

  • Lead preparation and communication of presentations

     

  • Understand and comply with ethical, legal and regulatory requirements applicable to our business
  • Transfer knowledge to technical staff by providing training and appropriate oversight to ensure competency

 

 

 

Desired Skills & Experience:

 

  • Ph.D. in Biochemistry, Microbiology, Biology, Cell Biology, Physiology, Molecular Medicine, Pharmaceutical Sciences or other related area with a focus on in vitro cellular systems, primary cell systems or related discipline required
  • 0-3 years’ post-graduate experience

     

  • Drug transporter and pharmacology expertise and practical in vitro experience with a background in pharmacokinetics/pharmacodynamics highly desired
  • Demonstrated expertise in area of research

     

  • Knowledge base on kidney in vitro models and applications to ADMETox field a plus

     

  • Working knowledge of human tissue samples highly desired
  • Experience in independent design of research experiments a plus
  • Strong verbal and written communication skills with demonstrated ability for novelty and

     

    consistency in experimental studies
  • Publications in peer reviewed journal are prerequisite
  • Must have excellent lab, communication, and presentation skills with ability to work

     

    closely within multidisciplinary team

 

Equal Opportunities:

 

 

 

Emulate, Inc. is an Equal Employment Opportunity Employer that is committed to inclusion and diversity. We take unbiased action to offer employment and advancement opportunities to all applicants, including minorities, women, protected veterans, and individuals with disabilities. Our methods for hiring include ensuring that all available opportunities are fairly promoted - via online globally available channels - in a manner accessible to all potential applicants.


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Postdoc analtical chemistry

Date Posted:
3/6/2017

Firmenich

NJ

We are seeking an exceptional, goal-oriented post-doctoral candidate to join a dynamic, cutting-edge research program in Analytical Chemistry. The incumbent will join the Analytical Innovation Group of our RESEARCH & DEVELOPMENT DIVISION at our North American headquarters located in PRINCETON, NEW JERSEY and collaborate with members of the company’s global R&D community. The successful candidate will be part of a team that is studying terpene peroxide chemistry. Strong analytical and organic chemistry knowledge or related expertise is required. Hands-on experience with chromatography would be a plus. The candidate must possess excellent oral and written communication skills, be comfortable working in a team environment and have a track record of scientific accomplishment.Main Tasks:

· Propose experiments and collaborate with research team to improve understanding of peroxide chemistry.

· Independently perform experimental activities to deliver key results in a timely manner.

· Continually identify opportunities to improve current procedures, protocols, and systems.

· Participate in data interpretation and information sharing with the wider research team.

· Present results at team and department meetings, and at external scientific conferences.

· Write manuscripts of scientific results and submit for publication in top-rated, peer-reviewed journals, patent applications, and/or internal company reports.

· Maintain up-to-date awareness of relevant knowledge and technologies.

 

Essential Skills and Expertise:

· PhD in Chemistry (Analytical or Organic preferred).

· Ability and motivation to quickly acquire new skills and craft creative solutions.

· Experiment design, data analysis, and scientific writing experience.

 

ADA

Reasonable accommodations may be made to enable individuals with disabilities to perform the essential function.

 

Firmenich is an Equal Opportunity Employer M/F/Disability/Veteran

 

At Firmenich, we create an environment in which employees are valued, motivated and encouraged to reach their full potential. We foster entrepreneurial spirit and imaginative teamwork with freedom to act within our strategic plans. We recruit and develop the best talents, rewarding them accordingly. We offer competitive pay, career growth opportunities, and an outstanding benefits program that features:

 

* Generous Paid Time Off!

* Quarterly Bonus Potential!

* Retirement Plans!

* 401(k) with Company Match!

* Low Cost Medical, Dental & Rx & Vision Coverage!

* Tuition Assistance for Employees and Children!

* Flexible Spending Accounts!

* Subsidized Cafeteria!

* Flex/Summer Hours!

* Tobacco-Free Campus!

* And Many More Employee-Friendly Programs!


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Medical Writer

Date Posted:
3/6/2017

Complete Medical Communications

CA

Job description

Complete Medical Communications (CMC), a division of McCann Complete Medical, is a leading global medical communications business with offices in the UK and US.

Our continued growth means that we are now looking to hire a Medical Writer or Senior Medical Writer with the right blend of skills to produce high-quality communications, and the ability to liaise directly and effectively with clients and clinical experts.

 Role & Responsibilities:

We are looking for a Medical Writer in our office to work on a variety of medical communications materials from print to online media, publications to international scientific meetings.

In this role you will:

Strive to achieve editorial excellence, producing clear, accurate, grammatically correct and creative written work on a variety of therapeutic areas appropriate to the project brief

  • Produce the full range of written communications items in accordance with the needs of the client, target audience, target publication medium, level of design/creativity
  • Proactively contribute creative ideas, concepts or suggestions to provide added value to projects
  • Effectively brief members of the project team, including time allocations, target audiences and client’s key messages
  • Lead specific projects, providing guidance to team members on client and project issues
  • Actively contribute to client/opinion leader meetings and facilitate these meeting as required
  • Monitor project costs against agreed budgets and notify Account Managers of any changes to specification

 

 

 

 

 

 

Applicants must have a life science degree (preferably a PhD) and previous writing experience. A proven track record in medical communications is essential, along with the ability to co-ordinate the delivery of editorial projects and to provide scientific excellence across a number of accounts and therapy areas.


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Medical Writer Oncology

Date Posted:
3/6/2017

National Comprehensive Cancer Network

PA

Job description

This position is responsible for the development, review, and update of scientific and clinical content for the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) and projects related to the NCCN Guidelines®, including but not limited to continuing education materials, conference reports, journal publications, and clinical content development for grant proposals, task force reports, and any NCCN Guidelines-related initiatives.

This position is located in Fort Washington, PA.

MAJOR RESPONSIBILITIES:

  • Perform PubMed literature searches; develop, review, edit, and update the assigned NCCN Guidelines
  • Track scientific literature with respect to designated NCCN Guidelines assignments
  • Attend NCCN Guidelines Panel meetings and web-based teleconferences
  • Participate in development and maintenance of the NCCN Guidelines in Guidelines Authoring Tool (GAT)
  • Develop and/or review clinical content for educational grant proposals including needs assessments, objectives, and faculty recommendations for NCCN educational programs
  • Develop, edit, and/or review clinical content for NCCN clinical information programs, including continuing education (CE) activities, conference reports, NCCN Guidelines Insights, JNCCN CE related articles, and external communication of Guidelines updates
  • Review permission requests and licensing of NCCN Guidelines information, including but not limited to print and electronic media, and integration into health-related information systems
  • Research and develop NCCN Task Force Reports based on panel presentations, discussion, and relevant scientific literature
  • Work on NCCN Guidelines-related initiatives

EDUCATION/RELATED EXPERIENCE:

  • PhD or equivalent experience with ability to evaluate clinical research
  • Experience in scientific/medical writing required
  • Experience in oncology strongly preferred

 SKILLS AND ABILITIES:

  • Must have excellent writing skills and the ability to formulate scientific/medical information in a clear and concise manner
  • Must possess strong attention to detail
  • Must be proficient in MS Office products
  • Must have strong interpersonal communication skills and the ability to interact effectively with internal and external personnel at various levels

 This position represents a unique opportunity to build a career with a premier organization. We offer competitive salary and excellent benefits.

  Send resume with salary history to jobs@nccn.org. EOE. No calls please.

Seniority Level

Associate

Industry

  • Nonprofit Organization Management

Employment Type

Full-time

Job Functions

  • Science

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Medical Science Liaison

Date Posted:
3/6/2017

Vigilant Biosciences

FL

About the company

Vigilant Biosciences’ vision is to create a world where cancer doesn’t stand a fighting chance.

Vigilant Biosciences is a leading innovator and developer of solutions that aid in the early detection and intervention of cancer. Our mission is to enhance the lives of patients and their families by providing transformative products that raise awareness of and enable early cancer intervention.

 Learn more about our organization at www.vigilantbiosciences.com.

 Please provide copy of resume with notice of interest. Responses without resumes will not be considered.

 Role Summary:

 The Medical Science Liaison will serve as Vigilant Biosciences’ spokesperson and educator, leveraging relationships with national and international key opinion leaders (KOLs) to bridge communications between clinical medicine and other areas of health care industry.

Responsibilities:

 Assisting in the management and administration of each component of active or pending clinical trials/studies

  • Assisting and preparing protocols and other necessary documents required for trial approval.

  • Monitoring and coordinating the clinical trial process at participating clinics, hospitals, and other medical centers.

  • Coordinating and facilitating various clinical trial support activities including query resolution, on-site test administration, site review / closure and collection of documentation required for clinical trial reports at trial completion.

  • Assisting in management of data quality control including product performance and data entry.

  • Continued literature review to maintain basic knowledge of Head and Neck Squamous Cell Carcinoma treatments, awareness of novel diagnostic technologies.

  • Possessing a clear understanding of the Vigilant product line including background publications and documentation that led to the current products and planned studies for the future

  • Maintaining basic knowledge of regulatory requirements surrounding current and future products.

  • All other duties as assigned by Management.

 

Key Collaborations:

 

The Medical Science Liaison will be responsible for fostering collaborative relationships with the following:

 

  • Clinical, R&D, Marketing, Business Development and ROQ (Regulatory, Operations, and Quality) Teams.

  • Distributors & customers to foster a sense of trust and reliability in the science behind Vigilant Biosciences products.

  • Key Opinion Leaders, medical and scientific community

  • Clinical trial sites and participants

 

Requirements:

 

  • Therapeutic/Diagnostic experience in Oncology is required.

     

     

  • Recent and relevant experience in Head and Neck Squamous Cell Carcinoma would be ideal but not required.

     

     

  • PhD in Research Science or MSN or RN; all preferred but not required.

  • Graduate-level, full-time clinical experience (minimum 2 years) with exposure to the basic sciences.

  • Experience in partnering with investigator(s) to initiate and oversee clinical trial activities.

  • Demonstration of proficiency in key skills and competencies, including exceptional clinical research and diagnostic product development knowledge.

  • Demonstrates the ability to assimilate new data quickly - stays current on trends and new information in the profession.

  • Highly articulate and persuasive during formal and informal presentations; able to convey complex, scientific ideas fluently to any audience.

  • Has the ability to tactfully provide scientifically sound, constructive feedback to national, regional and local thought leaders and speakers.

  • Actively listens to others and is adept at confidently stating expert opinion while respecting the positions of others - can exert diplomacy while standing firm on a position.

  • Builds and leverages strategic internal and external relationships to identify potential opportunities, partnerships and opportunities to provide value and improve quality of care for providers and patients.

  • Utilizes effective, professional communications to cultivate strong working relationships with internal and external colleagues (oral, written, presentation, rapport building, etc.)

  • Is able to work collaboratively on multidisciplinary teams to achieve desired outcomes

  • Skillfully plans, prioritizes and executes multiple responsibilities with minimal supervision in a highly dynamic work environment

  • Maintains a positive attitude during challenging situations

  • Should possess a true understanding of the MSL role with a true passion for the science.

 

Candidate Specifications:

 

Candidates possessing the following skills will be successful in this role:

 

  • Integrity and Trust - Trusted, authentic and self-aware. Operates by and adheres to core values and holds others accountable. Interacts with others in a way that give confidence in self and the organization he/she works for. Acts in the company’s best interest and puts that interest above personal gain, unit or office.

  • Superlative Communication Skills - Clearly conveys information and ideas to individuals and groups through a variety of communication modes; including formal presentations. Practices attentive and active listening; combines information from multiple sources and incorporates it into current discussion content.

  • Intellectual Curiosity - Interested and inquisitive about what’s going on throughout the organization, industry and larger business environment.

     

     

  • Adaptability - Effectively adjusts to changes in work processes and environment; alters behavior to align with evolving situations. Openly receives new ideas and accepts others perspectives.

  • Ability to Conceptualize - Mentally assembles diverse pieces of information and grasps their significance as a coherent, meaningful whole.

  • Attention to Detail - Thoroughness in accomplishing a task through concern for all the areas involved, no matter how small. Monitors and checks work or information and plans and organizes time and resources efficiently.

  • Teamwork/Collaboration - Develops and uses collaborative relationships to build informal or formal teams and accomplish team goals.

     

     

    Compensation commensurate with experience.

     

     

     

     

    Benefits

     

     

     

    We offer attractive, competitive compensation and benefits including, medical, dental, life, STD, Unlimited Time-Time, Flexible Work Program, 401k and an EAP program.

     

     

     

    Due to the anticipated volume of responses, we will contact only those candidates who most closely match our requirements. Only local candidates will be considered.


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Diversity and Inclusion Programs Associate

Date Posted:
3/6/2017

Novartis

MA

Position Description:
The Novartis Institutes for BioMedical Research (NIBR) has established undergraduate, post-baccalaureate, and global postdoctoral scholars programs with an emphasis on the inclusion of trainees with diverse backgrounds and disciplines. For information on these research training programs, visit http://www.nibr.com/careers/index.shtml and http://postdoc.nibr.com.

The Diversity & Inclusion Programs Associate will be part of the NIBR Diversity and Inclusion team. The position is for 1.5 years, will be located in Cambridge, MA, and will report to the Associate Director. The associate is expected to work 40 hours per week and work 50% with the Associate Director and 50% with the Global Head. The role will allow the associate to develop program management and scientific administration skills in a matrix environment.

The successful candidate should have a strong interest in developing training and education programs and be highly organized, adaptable, proactive, and know how to set priorities. The associate should possess excellent interpersonal skills and the ability to develop and maintain strong relationships within the department and across the global organization. The individual is expected to deliver on a wide variety of projects in a fast-paced environment.

Major Responsibilities:

  • Lead coordination of the summer undergraduate and post-baccalaureate scholar programs, outreach programs and events in the US, and help implement scientific education and professional development programs for research scholars and their mentors
  • Help establish and manage strong partnerships with institutions and organizations that support historically underserved populations in the sciences
  • Provide logistical support for the scholars programs including:
  1. Event coordination (e.g. campus visits, scientific seminars and symposia, summer programmatic elements, candidate interviews)
  2. Communications (e.g. advertising materials, brochures, banners, email correspondence)
  3. Operations (e.g. database updates, outreach travel coordination, supplies maintenance)
  • Project management and coordination with NIBR Global Head of Diversity & Inclusion

Minimum Requirements:

  • A degree in biomedical sciences, healthcare, education, or social sciences; experience with academic or drug discovery research is a plus
  • Experience in diversity, training program, and/or professional development initiatives is highly preferred
  • Excellent communication (written and spoken English) and presentation skills
  • Ability to handle sensitive matters professionally with diplomacy, discretion, and good judgment
  • Proficiency in MS Office (Word, Excel, PowerPoint, Outlook)
  • Aptitude for learning to use software applications
  • Strong data orientation and data analysis skills, is a plus
  • Expected travel: Up to 20% domestic

To Apply:
Please email cover letter and curriculum vitae (CV) to future.talent@novartis.com.


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Equity Research Associate

Date Posted:
3/6/2017

Needham & Company

NY

Needham & Company, LLC, a full-service investment bank has an immediate opening in its New York office for a Research Associate covering Biotechnology. The responsibilities include assisting the Senior Analyst in sector coverage, source and build relationships with industry contacts, preparation of industry reports and morning notes, financial modeling & analysis and maintaining contact with management teams of companies under coverage.

 

Desired Skills and Experience

The ideal candidate will possess an advanced science or medical degree (M.D., Ph.D. or equivalent) and 2-5 years industry or consulting experience, preferably in either Biotechnology or Pharmaceuticals; strong analytical & attention-to-detail skills and outstanding written and verbal communications skills. Experience with financial modeling and analysis is a major plus but not required.

 

Local candidates only; No phone calls please

 


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Technology Transfer Officers

Date Posted:
3/6/2017

UCLA

CA

UCLA Technology Development Group

The University of California, Los Angeles (UCLA) is known worldwide for the breadth and quality of its academic, research, health care, cultural, continuing education and athletics programs.  The faculty at UCLA comprise one of the most intellectually productive academic communities in the nation, and the institution receives over $1 billion in extramural research funding annually.  The UCLA Technology Development Group (TDG) is a group of professional staff dedicated to commercializing technology, collaborating with industry, and fostering entrepreneurship.  TDG is led by Amir Naiberg, the Associate Vice Chancellor for Technology Development, and President & CEO of UCLA Technology Development Corporation (TDC), a nonprofit company wholly controlled by UCLA that is focused on protecting and optimizing the discoveries and inventions developed through UCLA research.

Technology Transfer Officers (Life Sciences & Physical Sciences)

The UCLA Technology Development Group seeks two organized, proactive individuals with at least five years relevant professional experience--intellectual property, negotiation, licensing, venture capital, business development and/or product development in a university, research, start-up or technology-based environment--to serve as one member of the team of UCLA Technology Transfer Officers (TTOs). 

The duties of the TTOs include the following: (1) Building and Maintaining Relationships with campus constituents and external stakeholders; (2) Managing Campus Intellectual Property; (3) Negotiating and Documenting Agreements related to University Intellectual Property; (4) Marketing University Intellectual Property; and (5) Other Duties as may be assigned by supervisor or Associate Vice Chancellor. 

We are looking for two TTOs.  One will be assigned cases in the physical sciences space, and must possess a strong technical background in physical sciences, computer science, or engineering.  One will be assigned cases in the life sciences space, and must possess a strong technical background in the life sciences.

Qualifications

  • Advanced degree (MSc or PhD) OR 10 years with specific technology transfer experience or industry experience.
  • At least 2 years of industry experience. (preferred)
  • Strong interpersonal and communication skills (verbal, written and listening) to obtain relevant information, transmit relevant information at the appropriate level of detail and frequency, to know when to question for additional detail and sufficient diplomacy and tact to deliver difficult messages.
  • Experience with reviewing legal documents and negotiating terms of agreements. Ability to read legal documents and identify deal consistent and inconsistent points and ability to succinctly and accurately summarize negotiated deal points in a term sheet that might be used by others. (preferred)
  • Proficiency in conducting financial, market, and industry analysis in light of identified benchmarks in order to value early stage technology in advance of negotiations. (preferred)
  • Knowledge of copyright and patent law and ability to understand the legal and technical issues affecting protection, use and exploitation of such intellectual property. (preferred)

Applicant Information 

The University of California is an Equal Opportunity/Affirmative Action Employer advancing inclusive excellence. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected categories covered by the UC nondiscrimination policy. UC Nondiscrimination & Affirmative Action Policy


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Technology Transfer Fellowship - Negotiator

Date Posted:
3/6/2017

NCI

MD

The NCI Technology Transfer Center (TTC) has fellowship opportunities available to qualified candidates in the fast growing field of technology transfer. This fellowship opportunity combines a science, legal or business background with a new career in technology transfer. The TTC is responsible for negotiating agreements, promoting research partnerships with NCI scientists, and the patenting and licensing of NCI technologies. TTC also has a unit dedicated to marketing and outreach for these research opportunities and their underlying technologies to potential collaborators and licensees. This experience prepares the Fellow for technology transfer positions within universities, industry or the federal government. The TTC has offices in Rockville and Frederick, MD. Applicants should indicate the position(s) and location(s) of interest in their application. There are current openings for both the Combined and Negotiator Fellowships.

 

Technology Transfer Fellowship---Negotiator (Rockville or Frederick, MD Offices)

Candidate will be responsible for:

  • Drafting and negotiating Cooperative Research and Development Agreements (CRADAs) for NCI scientists and their industrial/academic research partners;
  • Drafting and negotiating licenses for NCI technologies;
  • Planning and negotiating Material Transfer Agreements (MTAs), Clinical Trial Agreements (CTAs) and other technology transfer agreements;
  • Managing patent prosecution of inventions and overseeing patent related issues for NCI scientists;
  • Developing technology transfer educational programs for scientists;
  • Working with the Invention Development and Marketing Unit, researchers and outside parties to help foster commercialization of technologies and collaborative/partnering opportunities;
  • Other duties as pertaining to intellectual property management and technology transfer.

    Stipends are determined by the level of education and number of years of experience post-graduation. Starting stipends for those with no experience are: Master's degree $35,500; Ph.D. $50,800. Starting stipends are higher with relevant work experience in technology transfer and/or additional, applicable degrees. Stipends are paid monthly in arrears. Health benefits are provided. Annual stipend increases may be given on the Fellow's anniversary date.

    To apply: Submit a copy of your resume or CV, a statement of interest explaining why you are interested in the TTC fellowship program, and two letters of recommendation by one of the following:

    E-mail to: kgriffin@mail.nih.gov Fax to: Attention: TTC Fellowship Coordinator (fax# 240-276-5504); or Mail to: Attention: TTC Fellowship Coordinator Technology Transfer Center National Cancer Institute 9609 Medical Center Drive., Rm. 1E530 MSC 9702, Bethesda, MD 20892


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Technology Transfer Fellowship - Negotiator and Marketing

Date Posted:
3/6/2017

NCI

MD

Technology Transfer Fellowship---Combined Negotiator and Marketing (Frederick, MD Office only)

This fellowship opportunity is designed to develop the unique skills associated with both negotiating technology transfer agreements and marketing a large portfolio. Approximately 50% time will be dedicated to each function.

Candidate will be responsible for:

  • The Negotiator responsibilities described above;
  • Working on marketing strategies/campaigns and descriptive marketing advertisements to attract research partners, and generating leads for technologies;
  • Developing comprehensive understanding of technology portfolio in order to serve as subject matter expert;
  • Advising intramural researchers on technology development strategies;
  • Monitoring responses to marketing campaigns and develop business relationships with company business development sources;
  • Acting as one of the liaisons between the NCI and outside parties requesting additional information on collaborative/partnering opportunities.

Minimum Requirements

  • An advanced degree in the sciences, law, business, economics, or public health. All candidates must have a background in the sciences;
  • Have received most current degree within the last 8 years;
  • S. citizen or permanent resident (must hold green card) eligible for citizenship within 4 years;
  • Excellent writing and speaking skills.  

Stipends are determined by the level of education and number of years of experience post-graduation. Starting stipends for those with no experience are: Master's degree $35,500; Ph.D. $50,800. Starting stipends are higher with relevant work experience in technology transfer and/or additional, applicable degrees. Stipends are paid monthly in arrears. Health benefits are provided. Annual stipend increases may be given on the Fellow's anniversary date.

To apply: Submit a copy of your resume or CV, a statement of interest explaining why you are interested in the TTC fellowship program, and two letters of recommendation by one of the following:

E-mail to: kgriffin@mail.nih.gov Fax to: Attention: TTC Fellowship Coordinator (fax# 240-276-5504); or Mail to: Attention: TTC Fellowship Coordinator Technology Transfer Center National Cancer Institute 9609 Medical Center Drive., Rm. 1E530 MSC 9702, Bethesda, MD 20892

DHHS/NIH/NCI are Equal Opportunity Employers.


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Sr Research Scientist Blood Components

Date Posted:
3/3/2017

Red Cross

MD

Job Description

In this role you will conduct complex research and/or development projects to support quality operations, regulatory compliance, and operational efficiency of blood services/products with an emphasis in the field of blood component storage.

Regular schedule will be Monday-Friday 1st shift at our Rockville, MD office. We support and reward our employees through competitive compensation, attractive health & wellness benefit options, paid time off, 401k matching, internal career growth opportunities and employee recognition & engagement programs.

Responsibilities

  • Independently conceives and designs research or development projects, and is successful in obtaining their support through funding from external agencies or through internal review.
  • Establish a record of successful research or development so that long term support is obtained and there is national and international recognition of the accomplishments.
  • Publish manuscripts reporting on experimental studies and reviews related to the area of scientific expertise.
  • Provide technical and scientific training and professional development opportunities to technicians, graduate students, and post-doctoral fellows.
  • Typically has unit-specific responsibilities with the scope of the job.

Qualifications

PhD with expert knowledge of scientific principles and concepts in the field of blood component research required. Minimum 5-8 years directly related experience required, 10+ years directly related experience strongly preferred. Reputation as emerging leader in field with sustained performance and accomplishments.
Apply now! Joining our team will provide you with the opportunity to make a difference every day.
The American Red Cross is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected veteran status, age, or any other characteristic protected by law.

The American Red Cross is a diverse nonprofit organization offering its employee’s professional development and growth opportunities, a competitive salary, comprehensive benefits, and a collaborative team spirit environment. To be considered for this position, please visit www.redcross.org/jobs to apply.

To view the EEOC Summary of Rights, click here: Summary of Rights

Posted 30+ Days Ago Full time RC911

As one of the nation’s premier humanitarian organizations, the American Red Cross is dedicated to helping people in need throughout the United States and, in association with other Red Cross networks, throughout the world. We depend on the many generous contributions of time, blood, and money from the American public to support our lifesaving services and programs.

At the American Red Cross, you will enjoy a collaborative work culture committed to the diversity of our people, programs, and services. We need people who want to contribute their individual talents to help their neighbors locally, across the country, and around the world. Whether you’re a recent graduate or an experienced professional, if you share our passion for helping people, join us in for a rewarding and challenging career opportunity that support our mission.


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Scientist Protein Chemistry

Date Posted:
3/2/2017

Biofactura

MD

Job description

  • Lead development and validation of various biosimilar product assays
  • Responsible for planning, conducting, execution and analysis of experiments using various techniques in protein analysis
  • Relevant skills include HPLC/U-HPLC (HILIC, RP, SEC, CEX, AEX, affinity), capillary electrophoresis (CE), mass spec, SDS-PAGE, IEF, ELISA, qPCR
  • Knowledge of protein purification methods and process development/scale-up is a plus
  • Knowledge of Good Laboratory Practices (GLP) including analytical method qualification/validation and current Good Manufacturing Practices (cGMP) are desired
  • This is an excellent opportunity to gain valuable experience with an innovative,  early-stage Biotech company and expand a career in the biopharmaceutical industry
  • Candidates should feel comfortable working in a high risk/high reward environment

 

Minimum Qualifications:

 

  • Masters or Doctoral degree in life sciences
  • Hands on experience in protein analytics (5+ years)
  • Excellent time management and proven ability to complete projects on time
  • Excellent level of initiative and quest for knowledge
  • Must be organized and self motivated
  • Must have excellent communication and writing skills
  • Familiarity with Microsoft Office (Word, Excel and Powerpoint etc.)
  • Must love to learn! 

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Clinical Scientist Immuno oncology

Date Posted:
3/2/2017

Ripple Media Group - Astra Zeneca

MD

Posted date: Feb. 27, 2017

At AstraZeneca we work together across global boundaries to make an impact and find answers to challenges. We do this with the upmost integrity even in the most difficult situations because we are committed to doing the right thing. We continuously forge partnerships that help pursue world-class medicines in new ways, combining our people’s exceptional skills with those of people from all over the globe. As a Clinical Scientist, Immuno-Oncology you’ll play a pivotal role in channelling our scientific capabilities to make a positive impact on changing patients’ lives. GMD (Global Medicines Development) drives late-stage development of our innovative pipeline, transforming exciting science into valued new medicines and ensuring patients around the world can access them.

AstraZeneca’s vision in Oncology is to help patients by redefining the cancer-treatment paradigm, with the aim of bringing six new cancer medicines to patients between 2013 and 2020. A broad pipeline of next-generation medicines is focused principally on four disease areas - breast, ovarian, lung and hematological cancers. As well as other tumor types, these are being targeted through four key platforms - immunotherapy, the genetic drivers of cancer and resistance, DNA damage repair, and antibody drug conjugates, underpinned by personalized healthcare and biomarker technologies.

Main Duties And Responsibilities

We’re currently looking for a Clinical Scientist - Immuno-oncology to play a leading role in our Clinical Research team. We’ll look to you to act as an expert in your area, working independently with guidance in only the most complex situations. You will serve as a close partner to the study physicians, coordinating the activity of a research team and holding full accountability for projects, often with Global impact.

This position will have key relationships internally with clinical project teams, marketing and business development, and brand or therapy area team leaders, and externally with regulatory bodies and external service providers. With our outstanding Oncology pipeline and a culture that empowers scientists to make bold decisions driven by science, this is an incredible opportunity to gain plenty of exposure to submissions and progress within a core therapeutic area.

Your main responsibilities will involve: developing and designing studies to determine the scientific or commercial viability of a particular drug or portfolio of drugs and interpret the results of these studies, either as the head of a team, or by providing expert input; contributing to the decision making process as a valued expert to determine the commercial and scientific viability of drugs; review and interpretation of medical and clinical trial data to reach conclusions; literature searches and authoring background section of the disease from the literature search. You will have responsibility for delivery of pieces of the trials and may lead submissions from a process standpoint.

Essential Requirements

    • An advanced degree (i.e. PhD, PharmD) in a relevant scientific discipline, supported by a proven record of managing and interpreting clinical trials.
    • Strong clinical study experience in Oncology. Industry experience is preferential but an academic setting focused on clinical trials is applicable.
    • Excellent collaboration and communication skills
    • Adept at working in a global setting and matrix environment.
    • Adept at partnering with a diverse team and delivering results through taking ownership of crucial program components.
    • Strong clinical, technical or disease area expertise

 

Next Steps - Apply today!

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience - it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity. If you know someone who would be a great fit, please share this posting with them.

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.


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Biomedical Engineer Fellow

Date Posted:
3/2/2017

Henry M Jackson Foundation

MD

The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HJF) is seeking a Biomedical Engineer Fellow to support the Center for Rehabilitation Sciences Research (CRSR)’s Regenerative Medicine Laboratory at the Uniformed Services University in Bethesda, Maryland. HJF provides scientific, technical and programmatic support services to CRSR. Candidate is responsible for leading, planning, and conducting biomedical research and development in support of a portfolio of projects in regenerative medicine that includes neuro-regeneration, orthopedic tissue repair, biomaterials design, 3D tissue engineering,and 3D bioprinting. Duties include leading teams of research personnel in the execution of R&D projects, serving as a key participant in the preparation of project proposals, authoring publications, and presenting the group’s work at national-level conferences. The candidate will be expected serve as a technical liaison to others who are assisting the group in the preparation of FDA filings to support clinical translation. The candidate will develop and maintain interactions with external partners at universities, companies, and other US Government laboratories.

 

Responsibilities:

  • Designs and executes experiments and ensures completion of technical milestones associated with each project
  • Leads small teams of researchers and establishes collaborations to keep projects on track; develops solutions to overcome technical challenges
  • Participates as a key member of the group to develop future strategy and plans for new projects; serve as a key innovator on the team
  • Leads the preparation of technical updates, reports, and publications
  • Maintains state-of-the-art knowledge of relevant technological developments regenerative medicine, physical medicine and rehabilitation.

 

Required Knowledge, Skills, and Abilities: Thorough understanding of the underling principles of physics, mathematics and physiology as it applies to biomedical engineering; knowledge of regenerative medicine and physical medicine & rehabilitation preferred

 

Minimum Education/Training Requirements: PhD in bioengineering correlated biomedical discipline 0-3 years experience as a post-doc in a bioengineering-related field.

 

Minimum Experience: translational R&D is very desirable.

 

Physical Capabilities: Ability to sit at a computer for long periods of time

 

Work Environment: Office environment

 

HJF is an equal opportunity and affirmative action employer. Allqualified applicants will receive consideration for employment withoutregard to race, color, religion, sex, sexual orientation, genderidentity, national origin, disability, or protected veteran status.

Contact the job poster

 
Job posted by

Jena Peters

Recruiting Coordinator at The Henry M. Jackson Foundation for the Advancement of Military Medicine
Washington D.C. Metro Area
Send InmailSend Inmail to Jena

Industry

Hospital & Health Care

Employment type

Full-time

Experience

Associate

Job function

Human Resources
 

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Meet The Henry M. Jackson Foundation for the Advancement of Military Medicine

Corporate Positions at HJF

Company

The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HJF) is a global organization dedicated to advancing military medical research. We serve military, medical, academic and government clients by administering, managing and supporting preeminent scientific programs that benefit members of the armed forces and civilians alike.

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Associate Scientific Liaison Chemical Medicines

Date Posted:
3/2/2017

USP Pharmacopeia

MD

 

This is a non-supervisory scientific position in the Chemical Medicines Department (CMD) reporting to Director/Team Leader.  The incumbent is responsible for the development and revision (modernization) of monographs for small molecular weight pharmaceuticals (drug substances and the associated dosage forms) in the USP-NF and supports USP Expert Committee and associated Expert Panels. The department works closely with Reference Standards Evaluation (RSE) Compendial Development Laboratories (CDL) within Global Laboratory Organization (GLO) and other departments such as Publications (PUBS) and Executive Secretariat and COE Support.

 

Roles and Responsibilities:

  • Develops new monographs and modernizes existing monographs based on supporting data submitted by USP global laboratories and external sponsors.
  • Evaluates monograph tests, procedures and acceptance criteria;
  • Redesign existing official monographs;
  • Works closely with a team of high-performing scientists responsible for the development and revision of documentary standards;
  • Works with USP staff, regulatory bodies, stakeholders, and other pharmacopeias as related to monograph development;
  • Provides information to the relevant USP Expert Committee(s) in support of monograph development;
  • Serves as a mentor for other staff and leads training efforts, as needed;
  • Serves as a member on USP teams, as needed;
  • Prepares manuscripts for publication by USP (e.g., stimuli articles) or in peer-reviewed journals;
  • Represents USP at scientific conferences/meetings, outreach visits and other events sponsored by USP and/or pharmaceutical industry and regulatory agencies;
  • Participates in the development and/or review of USP’s professional education course materials and may serve as an instructor, as needed.
  • Collaborates closely with CDL, CMD, RSE, GLO, PUB and ES& COE Support on monograph-related issues;
  • Tracks and reports frequently on the status of assignments to management;
  • Performs other duties as assigned.

Required Skills

 

  • Able to establish and nurture relationships with individuals of varying backgrounds and learning styles.
  • Able to operate independently where appropriate, yet understands when to escalate issues and how to establish effective working relationships.
  • Strong presentation and communication skills (written and oral).
  • Well-developed organizational, interpersonal communications, negotiation, writing, and strong listening skills.
  • Knowledge of internet and electronic database searches helpful.
  • Practical experience in scientific, analytical techniques.
  • Project Management skills required.
  • Knowledge of the pharmaceutical industry and the associated regulatory framework is essential.
  • Ability to prioritize tasks and manage multiple projects simultaneously.
  • Must be able to share technical information with non-technical or non-scientific staff, and to communicate effectively with representatives from pharmaceutical companies, government, and academic institutions.

Required Experience

 

Education and Experience:

 

Ph.D. in Chemistry, Biochemistry or allied field with a minimum of 8 years, or M.S. and 10, or B.S. and 15 years of relevant experience with USP-NF tests and standards required. Minimum of 8 years of experience with analytical techniques such as chromatography wet chemistry, spectroscopy, titration, etc. required.  Knowledge of compendial standards related to pharmaceutical product/industry also required as is knowledge of regulatory requirements and guidelines for pharmaceuticals (e.g. FDA, ICH, etc). An equivalent combination of experience and education may be substituted.

 

Supervisory Responsibilities:

None

 

 

The U.S. Pharmacopeial Convention (USP) is a scientific nonprofit organization that sets standards for the identity, strength, quality, and purity of medicines, food ingredients, and dietary supplements manufactured, distributed and consumed worldwide. USP’s drug standards are enforceable in the United States by the Food and Drug Administration, and these standards are used in more than 140 countries.

                                  

Being a part of USP means belonging to a diverse culture made up of more than 1,000 talented professionals working together at five international locations.  We share our expertise in science, IT, human resources, quality assurance, communications, administrative management, and more...all to support an overall mission dedicated to making a difference by providing standards and programs that help improve the quality of medicines, dietary supplements, and foods worldwide.

 

USP is proud to be an equal employment opportunity employer (EEOE) and affirmative action employer. Employment selection and related decisions are made without regard to sex, race, age, disability, religion, national origin, color, veteran status, sexual orientation, gender identity or any other protected class. We are committed to working with and providing reasonable accommodation to individuals with disabilities.

 

 


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Medical Writer

Date Posted:
3/2/2017

Sanaria

MD

Medical Writer

Sanaria is now embarking on an ambitious program designed to lead to licensure, and will be conducting clinical trials at multiple sites in Africa, Europe, and the United States. Sanaria is currently recruiting for a Medical Writer experienced with Clinical Protocols, Amendments, Reports, and Manuscripts, ideally with background in vaccine (or drug) development.

Responsibilities

  • Development, writing, editing, and finalization of clinical documentation required prior to the initiation of a clinical study, including clinical study protocols, informed consent documents and other clinical documentation given to volunteers
  • Development, writing, editing, and finalization of clinical documentation required for submission to regulatory health authorities and ethical review committees during the course of a clinical study, including interim safety report, abstracts for scientific presentation, and integrated summaries of efficacy and safety
  • Development, writing, editing, and finalization of clinical documentation required for study close-out including final clinical study reports, final safety reports, and manuscripts/scientific papers
  • Analysis of clinical data, compilation of clinical data tables, and integration of clinical data summaries into clinical study reports and manuscripts as appropriate
  • Coordination of team review and editing of clinical regulatory documentation in close collaboration with the Chief Medical Officer, Chief Executive Officer, Principal Investigators, and operational staff to develop quality study protocols, informed consent documents and other clinical documentation
  • Development of processes, templates and libraries, by creation of a Manual of Procedures to support creation of study protocols, study reports and other clinical documentation

Requirements

  • Bachelor's degree, Master's degree or PhD in science- or public health-related field
  • 3-5 years of prior vaccine trial experience is required
  • Excellent oral and written communication skills
  • 3-5 years of prior experience in writing and developing clinical documents such as clinical study reports, safety reports, and clinical protocols, as well as informed consent forms, and other clinical documentation provided to volunteers
  • Demonstrated knowledge of protocol structure, clinical data analysis and presentation
  • Demonstrated knowledge of GCPs
  • Strong analytical skills/excellent interpersonal skills/strong leadership abilities
  • Proven ability to demonstrate strong decision making and problem solving skills
  • Strong time management skills and the proven ability to meet deadlines
  • Basic knowledge of windows-based software programs
  • U.S. citizenship or permanent eligibility to work legally in the U.S. is required

 


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Technical Writer

Date Posted:
3/2/2017

Personal Genome Diagnostics

MD

Personal Genome Diagnostics is looking for an extraordinary and highly motivated scientist or engineer with excellent technical communication skills and regulatory experience to join a fast-paced and rapidly growing company to develop and launch medical devices with cutting-edge next-generation sequencing technologies. This individual will work cross-functionally with product development teams and support all aspects of technical writing in clinical activities and regulatory submissions as well as post-launch customer support activities. This individual will interface with R&D, Clinical, Regulatory and Customer Support staff to create, edit, and finalize a variety of documents including SOPs, study protocols, training procedures, clinical study reports, package insert, product labeling and submissions to the Food and Drug Administration (FDA). A successful candidate will have strong ability to support multiple projects simultaneously in an expanding product pipeline. Concise and clear high-quality technical writing is a must.

 

Responsibilities:

  • Interface with cross-functional project team members including R&D, Clinical and Regulatory Affairs, Customer Support and Marketing to plan, write, edit and finalize clinical and regulatory related technical documentations for clinical/reference lab users, physicians, and patients.
  • Ensure the accuracy and timely creation, edit, review, and revision of all cross-functional documents supporting regulatory submissions. Interface with product development team to create, edit, update and maintain SOPs, clinical protocols, clinical study reports, regulatory submissions, product package insert, labeling, and technical bulletins etc. Understanding of Quality System standards and how they impact package insert and product labeling.
  • Interface with software/hardware development team and customer support team to create, edit and update user manuals and user training manuals.
  • Ensures content contained in all documentation conforms to regulatory design control and legal requirements. Ensure high-quality documentation with regards to scientific content, organization, clarity, accuracy, format, consistency, and adherence to regulatory and quality guidelines.
  • Translate complex product information into concise, regulatory compliant, easy-to-follow instructions for internal and external users and customers.
  • Develop and design instructional and informational tools needed to assure safe, appropriate, and effective use of the next generation sequencing products including reagents, software, and hardware. 
  • Quickly learn and apply new tools, processes, and standards. Demonstrate adaptability and forward thinking to embrace technological or organizational growth.
  • Support one or more product development programs. May perform other duties as required or assigned.

 

Qualifications:

  • BS in biology, biochemistry, bioengineering or other relevant life sciences and engineering degrees. Advanced degree with an MS or Ph.D. is preferred.
  • Excellent English writing skills with more than 3-5 years of technical writing experience. Excellent grammar, spelling, editing, organization, teamwork and written and verbal communication skills are a must.
  • Previous technical writing experience with clinical trial protocols and/or FDA regulatory submissions is preferred.
  • Previous experience working in a medical device or other regulated environment/industry with FDA design control, GCLP, GMP and ISO regulations experience is preferred.
  • Experience with Next Generation Sequencing is preferred.
 

- See more at: http://www.personalgenome.com/job/technical-writer/#sthash.CnSxnOms.dpuf


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Scientist I Mass spectroscopist antibody engineering

Date Posted:
3/2/2017

Macrogenics

MD

MacroGenics is a leader in the discovery and development of innovative medicines that utilize our next generation antibody-based technologies.  Our team of 300+ dedicated individuals is advancing a pipeline of product candidates to treat patients with cancer as well as various autoimmune disorders and infectious diseases.  Our products and platforms have attracted multiple partnerships with leading pharmaceutical companies around the globe.

 

The Company considers its employees to be its most valuable asset and we are committed to providing opportunities for individuals to learn and grow as a means to further their professional development. MacroGenics' corporate culture promotes an atmosphere of innovation, open communication and teamwork where employees can see firsthand how they contribute to the success of the organization.

 

Summary of Position

The Scientist I is responsible for characterizing biologic drug candidates by mass spectrometry and investigating the physiochemical properties, including early formulation and stability assessments.  He/she will need to collaborate with biologists and process scientists to ensure the delivery of therapeutic molecules with the desired biological and biophysical properties and be responsible for purifying recombinant proteins and antibody reagents for biologics discovery programs.

 

Responsibilities and Job Duties:

  • Perform characterization of primary structure including post translational modifications, disulfides, glycosylation, oxidation, deamidation, asp isomerization, and proteolysis cleavage sites
  • Ensure that the correct laboratory chemicals and consumables necessary to use the mass spectrometer are always available and for contacting the appropriate service engineers to provide regular maintenance and/or repair the equipment in a timely manner
  • Conduct biophysical characterization of proteins with MALS, DSC, HPLC, CIEF, and DLS
  • Conduct protein formulation and stability testing to determine appropriate storage conditions
  • Provide biophysical scientific guidance to the protein purification group for troubleshooting problems
  • Assist with the interface between research and development for technology transfer of lead drug candidates. 
  • Present ongoing updates to research and development project teams to ensure open and timely communications between the teams resulting in better understanding and a smooth transition
  • Maintain accurate and timely laboratory notebooks and other data records to provide crucial information regarding discovery of inventions and to best understand the experimental process
 

Qualifications

Education & Experience – Scientist I

  • Ph.D in Analytical Chemistry, Pharmaceutical Sciences, Biochemistry, or related field
  • A minimum of two years of experience in the pharmaceutical industry characterizing proteins
  • Background in molecular biology, protein chemistry, antibody or protein engineering, and cell biology

Education & Experience – Associate Scientist II

  • M.S. in Analytical Chemistry, Pharmaceutical Sciences, Biochemistry, or related field with a minimum of 10 years of related experience
  • A minimum of three years of experience in the pharmaceutical industry characterizing proteins
  • A strong background in molecular biology, protein chemistry, antibody or protein engineering, and cell biology

Knowledge, Skills and Abilities    

  • Knowledge of various analytical methodologies including but not limited to mass spec, DSC, ITC, MALS, DLS, and CE
  • Experience in peptide mapping
  • Ability to provide a critical interpretation of results
  • Trouble shooting skills
  • Ability to multitask and handle multiple priorities in a fast-paced environment
  • Excellent written and verbal communications skills
  • Strong interpersonal skills for interfacing with upstream and downstream functions, including Development
  • Problem-solving skills and independent research experience demonstrated by strong publication records
  • Ability to work in cross-functional teams

Preferred Qualifications:

  • Experience with protein engineering and molecular evolution techniques
  • Relevant experience in biotech or pharmaceutical companies
  • Experience in manipulation of large size DNA and vectors
  • Protein and antibody production in mammalian cells using transient and stable expression vectors
  • Protein characterization by biochemical and biophysical assays
  •  Working knowledge of various instrumentation include FACS, HPLC, Biacore etc.

Supervisory Responsibilities:

None 

 

 

Veteran Friendly Employer

 

Statement

MacroGenics is proud to be an equal opportunity employer. Employment selection and related decisions are made without regard to race, color, national origin, sex, gender identity, sexual orientation, religion, age, disability, protected veteran status, or any other characteristic protected by federal, state or local law. We are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the employment process, please email info@macrogenics.com or call (301) 354-3566 and/or 711 for TTD/TTY service.


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Scientist II Purification

Date Posted:
3/2/2017

Macrogenics

MD

MacroGenics is a leader in the discovery and development of innovative medicines that utilize our next generation antibody-based technologies.  Our team of 300+ dedicated individuals is advancing a pipeline of product candidates to treat patients with cancer as well as various autoimmune disorders and infectious diseases.  Our products and platforms have attracted multiple partnerships with leading pharmaceutical companies around the globe.

 

The Company considers its employees to be its most valuable asset and we are committed to providing opportunities for individuals to learn and grow as a means to further their professional development. MacroGenics' corporate culture promotes an atmosphere of innovation, open communication and teamwork where employees can see firsthand how they contribute to the success of the organization.

 

Summary of Position

This position is responsible for the development, characterization and validation of purification processes for late-stage pipeline products. The individual will help establish late stage characterization and validation strategies while also participating in process development activities.  The position necessitates a collaborative approach with other Development functional groups, Manufacturing, Validation and Regulatory Affairs towards the goal of transitioning products from development to commercialization. 

 

Responsibilities and Job Duties:

  • Establish process characterization and validation strategy
  • Design, coordinate and execute process characterization studies
  • Design and execute small scale and large scale validation studies
  • Presentation of validation and characterization study results to internal teams
  • Draft protocols and reports in support of regulatory filings
  • Write the relevant sections for regulatory submission
 

Qualifications

Scientist I:

Education

BS, MS, or PhD in the biological sciences or related field

 

Experience

  • BS with a minimum of 12 years of experience, MS with a minimum of 9 years of experience or PhD with no previous experience
  • Minimum of 2 years of biotech industry experience with a BS or MS

Scientist II:

Education

BS, MS, or PhD in the biological sciences or related field

 

Experience

  • BS with a minimum of 14 years of experience, MS with a minimum of 11 years of experience or PhD with a minimum of 2 years of experience
  • Minimum of 5 years of biotech industry experience with a BS or MS

Knowledge, Skills and Abilities – Scientist I and II

  • Possess in-depth understanding of downstream unit operations
  • Understanding of downstream process development and process transfer to manufacturing
  • Demonstrated ability to perform small-scale model studies using Design of Experiments (DOE) approach
  • Experience operating purification equipment such as AKTA or equivalent 
  • Proven track record of authoring, executing and reviewing both large and small scale validation protocols
  • Ability to collaborate with and influence other functional areas such as Regulatory Affairs and Process Validation
  • Excellent technical writing skills and oral communication skills
  • High energy results driven individual
  • Willingness to be hands on

Preferred Qualifications – Scientist I and II

  • Experience performing biologics analytical techniques (HPLC, Capillary Electrophoresis, ELISA)
  • Previous management experience

Supervisory Responsibilities:


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Scientist II Analytical

Date Posted:
3/2/2017

Macrogenics

MD

Overview

MacroGenics is a leader in the discovery and development of innovative medicines that utilize our next generation antibody-based technologies.  Our team of 300+ dedicated individuals is advancing a pipeline of product candidates to treat patients with cancer as well as various autoimmune disorders and infectious diseases.  Our products and platforms have attracted multiple partnerships with leading pharmaceutical companies around the globe.

 

The Company considers its employees to be its most valuable asset and we are committed to providing opportunities for individuals to learn and grow as a means to further their professional development. MacroGenics' corporate culture promotes an atmosphere of innovation, open communication and teamwork where employees can see firsthand how they contribute to the success of the organization.

 

Summary of Position

This position will be responsible for development and full lifecycle support of analytical release methods for biopharmaceutical products using HPLC and CE.  This individual will also be responsible for managing and mentoring direct reports to support these activities.

 

Responsibilities and Job Duties:

  • Develop analytical release methods for biopharmaceutical products
  • Support method lifecycle through qualification and validation
  • Perform analyses to support release and stability of candidate products
  • Author analytical sections of IND/BLA as well as technical documentation and procedures
  • Support degradation pathway assessments
  • Operate and maintain analytical instrumentation (e.g. HPLC, CE, Spectrophotometer)
  • Manage direct reports to support these activities
 

Qualifications

Education & Experience

  • BS, MS, or PhD in Biochemistry, Chemistry or life sciences
  • Experience in Biologics required
  • Must have experience training or managing more junior staff

Scientist I

  • BS degree with a minimum of 12 years of experience with at least 5 years of relevant industrial experience analyzing biological molecules
  • MS degree with a minimum of 9 years of experience with at least 3 years of relevant industrial experience analyzing biological molecules
  • Ph.D. degree with relevant experience analyzing biological molecules

Scientist II

  • BS degree with a minimum of 14 years of experience with at least 8 years of relevant industrial experience analyzing biological molecules
  • MS degree with a minimum of 11 years of experience with at least 6 years of relevant industrial experience analyzing biological molecules 
  • Ph.D. degree with a minimum of 2 years of experience with at least 2 years of relevant industrial experience analyzing biological molecules

Knowledge, Skills and Abilities - Scientist I and II

  • Expertise in analytical separation techniques and equipment
  • Ability to operate and troubleshoot HPLC, UPLC, and CE instrumentation
  • Strong technical writing skills

Preferred Skills

  • Experience with analytical comparability design and execution
  • Experience with late stage development preferred

Supervisory Responsibilities:

  • Associate Scientist II
  • Research Associate II

 

 

Veteran Friendly Employer

 

Statement

MacroGenics is proud to be an equal opportunity employer. Employment selection and related decisions are made without regard to race, color, national origin, sex, gender identity, sexual orientation, religion, age, disability, protected veteran status, or any other characteristic protected by federal, state or local law. We are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the employment process, please email info@macrogenics.com or call (301) 354-3566 and/or 711 for TTD/TTY service.


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Technical Sales Consultant

Date Posted:
3/2/2017

Miltenyi Biotec

TX

Technical Sales Consultant - Houston, TX

 

Your tasks

As a member of the Miltenyi Biotec North America Sales Team, you will be responsible for our full line of immunology based products throughout the Houston based territory. You will use your in-depth knowledge and expert technical skills to acquire new customers from biotechnology companies, academic research institutions, and pharmaceutical companies, while simultaneously augmenting existing customer relationships. In addition, you will go above and beyond by analyzing the market for new product opportunities and acting as a knowledgeable resource for customers who have questions or product-related issues. Your outgoing nature and ability to gain buy-in from others will help Miltenyi Biotec showcase itself successfully and professionally, and as a result grow the sales of the company overall.
 

Your profile

  • You have a Ph.D., M.S., or B.S. degree from a four-year college or university
  • You desire more than the typical 9am-5pm job
  • You have three to five years of experience in the life sciences environment, and a thorough grasp of either immunology, stem cell biology, cancer biology, and/or molecular biology
  • You have exceptionally impressive organizational skills
  • Strong communication and presentation skills help you to persuade others, which is one of your greatest strengths
  • You are comfortable traveling over 50% of the time

Physical Demands

The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. While performing the duties of this job, the employee is regularly required to walk; use hands to finger, handle, or feel; reach with hands and arms, talk and hear. The employee is required to stand; climb or balance and stoop, kneel, crouch. The employee must occasionally lift and/or move up to 75 pounds (dual lift). Specific vision abilities required by this job include close vision, color vision, peripheral vision, depth perception and ability to adjust focus. Must have ability to handle more than one task at a time and must work at a rapid pace while maintaining attention to detail. Must be able to travel routinely by car and plane.


Miltenyi Biotec is expanding and evolving. Our culture is one that empowers you to embrace new challenges and influence change. Join a fresh and collaborative working environment that encourages contribution, innovation, and growth.

We empower great science. For more than 25 years, Miltenyi Biotec has provided innovative tools, instruments, and solutions that advance biomedical research and cellular therapy. We are 1,800 scientists, engineers, physicians, support specialists, marketers, and more – all dedicated to improving scientific understanding and impacting human lives. At our headquarters campus and offices worldwide, fresh ideas become unique products.

Miltenyi Biotec, Inc. is an EO Employer – M/F/Veteran/Disability

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Flow Specialist

Date Posted:
3/2/2017

Miltenyi Biotec

NY

Flow Cytometry Specialist - New York

 

Your tasks

As a member of the Miltenyi Biotec North America Sales Team, you will be responsible for our flow instruments throughout the Greater New York area. You will use your instrument sales acumen, flow cytometry knowledge, and technical skills to acquire new customers from biotechnology companies, academic research institutions, and pharmaceutical companies, while simultaneously augmenting existing customer relationships. In addition, you will go above and beyond by analyzing the market for new product opportunities and acting as a knowledgeable resource for customers who have questions or product-related issues. Your outgoing nature and ability to gain buy-in from others will help Miltenyi Biotec showcase itself successfully and professionally, and as a result grow the sales of the company overall.
 

Your profile

  • You have a B.S., M.S., or Ph. D. degree in life sciences; or equivalent combination of education and experience
  • You desire more than the typical 9am-5pm job
  • You have 3+ years of hands-on experience with flow cytometers and experience in instrument sales in the life sciences environment
  • You have exceptionally impressive organizational skills
  • You possess the instincts of a hunter, which will easily translate into you successfully finding new sales leads
  • Strong communication and presentation skills help you to persuade others, which is one of your greatest strengths
Miltenyi Biotec is expanding and evolving. Our culture is one that empowers you to embrace new challenges and influence change. Join a fresh and collaborative working environment that encourages contribution, innovation, and growth.

We empower great science. For more than 25 years, Miltenyi Biotec has provided innovative tools, instruments, and solutions that advance biomedical research and cellular therapy. We are 1,700 scientists, engineers, physicians, support specialists, marketers, and more – all dedicated to improving scientific understanding and impacting human lives. At our headquarters campus and offices worldwide, fresh ideas become unique products.

Miltenyi Biotec is an EO Employer – M/F/Veteran/Disability
 
 

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Flow Specialist

Date Posted:
3/2/2017

Miltenyi Biotec

CA

Flow Cytometry Specialist - Bay Area

 

Your tasks

As a member of the Miltenyi Biotec North America Sales Team, you will be responsible for our flow instruments throughout a Bay Area based territory. You will use your instrument sales acumen, flow cytometry knowledge, and technical skills to acquire new customers from biotechnology companies, academic research institutions, and pharmaceutical companies, while simultaneously augmenting existing customer relationships. In addition, you will go above and beyond by analyzing the market for new product opportunities and acting as a knowledgeable resource for customers who have questions or product-related issues. Your outgoing nature and ability to gain buy-in from others will help Miltenyi Biotec showcase itself successfully and professionally, and as a result grow the sales of the company overall.
 

Your profile

  • You have a Ph.D. or MS in life sciences
  • You desire more than the typical 9am-5pm job
  • You have 3+ years of hands-on experience with flow cytometers
  • You have 1-2 years of experience in sales or as a field application scientist
  • You have exceptionally impressive organizational skills
  • You possess the instincts of a hunter, which will easily translate into you successfully finding new sales leads
  • Strong communication and presentation skills help you to persuade others, which is one of your greatest strengths

Requirements

  • Ph.D. or M.S. degree from a four-year college or university; three plus years of flow cytometry experience and one to two years sales experience or field application scientist experience in the life sciences environment; or equivalent combination of education and experience
  • Flow cytometry experience and familiarity with a variety of sales concepts, practices, and procedures would be preferred
  • Must possess a valid driver’s license, evidence of insurance/insurability, ability to receive appropriate clearance to access restricted government accounts, and be authorized to work in the U.S.

Physical Demands

The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

While performing the duties of this job, the employee is regularly required to walk; use hands to finger, handle, or feel; reach with hands and arms, talk, and hear. The employee is required to stand; climb or balance and stoop, kneel, crouch. The employee must occasionally lift and/or move up to 50 pounds. Specific vision abilities required by this job include close vision, color vision, peripheral vision, depth perception and ability to adjust focus. Must have ability to handle more than one task at a time and must work at a rapid pace while maintaining attention to detail.

Work Environment

The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. This job is performed in a variety of facilities. Each person performing this job must have a home office environment, which is temperature controlled. This job requires the person to be mobile to visit customer sites. Due to the travel requirements, this position may be exposed to natural elements of nature.


Miltenyi Biotec is expanding and evolving. Our culture is one that empowers you to embrace new challenges and influence change. Join a fresh and collaborative working environment that encourages contribution, innovation, and growth.

We empower great science. For more than 25 years, Miltenyi Biotec has provided innovative tools, instruments, and solutions that advance biomedical research and cellular therapy. We are 1,700 scientists, engineers, physicians, support specialists, marketers, and more – all dedicated to improving scientific understanding and impacting human lives. At our headquarters campus and offices worldwide, fresh ideas become unique products.

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Flow Application Scientist

Date Posted:
3/2/2017

Miltenyi Biotec

GA

Flow Cytometry Application Scientist - Mid-Atlantic

 

Your tasks

As a member of the Miltenyi Biotec North America Instrumentation Team, you will be responsible for applications support of our flow cytometry portfolio throughout a Mid-Atlantic based territory. You will rely on your technical expertise to provide trainings for installations, demonstration support, and assay development on the MACSQuant line of instruments including the newly launched Tyto. Your excellent communication skills will come into play as you perform presales presentations, technical seminars and training for individuals and groups. In addition, you will work in tandem with the sales, marketing, and service teams to represent Miltenyi Biotec at tradeshows and product seminars. Altogether, your customer-focused understanding and superb teamwork skills will help build the continued success of Miltenyi Biotec as a whole.
 

Your profile

  • You have a Ph.D. or MS in Cell Biology, Immunology, Neuroscience, Molecular Biology, or a similar field
  • You have a minimum of 3 years of hands-on experience with flow cytometry
  • You have exceptionally impressive organizational skills
  • Strong communication and presentation skills are a strength of yours Travel fits your Lifestyle

Requirements

  • Ph.D. or M.S. degree from a four-year college or university; four years’ experience in Cell Biology, Immunology, Neuroscience, Molecular Biology, or a similar field
  • A minimum of 3 years of flow cytometry experience; solid understanding of procedures, concepts, and lab experience; or equivalent combination of education and experience 
  • Must possess a valid driver’s license, evidence of insurance / insurability and ability to receive appropriate clearance to access restricted government accounts.
  • Must be authorized to work in the U.S.

Physical Demands

The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job.

While performing the duties of this job, the employee is regularly required to walk; use hands to finger, handle, or feel; reach with hands and arms, talk and hear. The employee is required to stand; climb or balance and stoop, kneel, crouch. The employee must occasionally lift and/or move up to 75 pounds (dual lift). Specific vision abilities required by this job include close vision, color vision, peripheral vision, depth perception and ability to adjust focus. Must have ability to handle more than one task at a time and must work at a rapid pace while maintaining attention to detail. Must be able to travel routinely by car and plane.


Miltenyi Biotec is expanding and evolving. Our culture is one that empowers you to embrace new challenges and influence change. Join a fresh and collaborative working environment that encourages contribution, innovation, and growth.

We empower great science. For more than 25 years, Miltenyi Biotec has provided innovative tools, instruments, and solutions that advance biomedical research and cellular therapy. We are 1,700 scientists, engineers, physicians, support specialists, marketers, and more – all dedicated to improving scientific understanding and impacting human lives. At our headquarters campus and offices worldwide, fresh ideas become unique products.

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Process Development Scientist

Date Posted:
3/2/2017

Jecho Labs

MD

Company Overview:

Jecho Laboratories, Inc. (Jecho) is a biopharmaceutical company that develops innovative therapeutic biologics, including therapeutic monoclonal antibodies, cytokines, immunotoxins, and vaccines to address a broad range of infectious diseases as well as treatment of cancer. The company headquarters are located in Frederick Maryland, USA.

 

We are seeking a Process Development Scientist to join our R&D in Frederick, MD. Qualified individuals will play an important role in process development for bio-therapeutics. The candidate must work independently on experiment design, data analysis, summary and report. The candidate is expected to be well organized, multi-functional and self-motivated.

 

Essential Job Functions:

  • Perform literature search and design experiment with sound scientific rational and logics.
  • Independently design and conduct experiment for up and downstream process development.  
  • Design and conduct assays including but not limited to SDS-PAGE, Western blot, ELISA, HPLC and other assays.  
  • Assist tech transfer activity such as providing operation parameters, writing technical report and perform tech transfer.
  • Generate, evaluate, and maintain critical data in a highly organized manner.
  • Collaborate and coordinate with colleagues in other departments for developing a robust, high purity/yield, economic and scalable recombinant production process.
  • Write scientific proposal, progress report to support the corporate goal.

 

Minimum Requirements:

  • Ph.D. in biological science, biotech/bioengineering or other related areas. 1-2 years’ experience in pharmaceutical or biotechnology field. Or master with more than 5 years’ experience in related field.
  • Strong hands on experience of recombinant biologic products expression, purification and analysis, as well as bio-product analysis. Ability of consistent operation and analyze/interpret data.
  • Diverse knowledge and experience in various relevant areas, including but not limited to molecular/cell biology, biochemistry, neuroscience, immunology, and others.
  • Capable of performing multiple functions in a fast paced environment. Strong technical protocol/report writing and good presentation skills are required.
  • Excellent record keeping abilities to adequately record and to keep documents in support of drug development and approval.
  • GMP experience is a plus. Aware of general FDA regulatory requirements associated with biological approval for human use.
  • Skillful on basic computer software including Excel, Word and PowerPoint.
  • This position requires lifting of up to 30 lbs occasionally, and also requires physical activity such as standing for prolonged periods.

 


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Senior Manager Professional Education

Date Posted:
3/2/2017

ACell

MD

Title: Senior Manager, Professional Education
Department: Compliance
Location: Columbia, MD
Type: Full-time

Job Summary
Professional Education is a function within the Compliance department and this position will report to the VP of Compliance.

As a leader in the field of regenerative medicine, ACell has an obligation to maintain a steadfast reputation as a company that is ethically responsible. Our comprehensive Ethics and Compliance program is at the core of this effort. The Compliance program supports and enhances all of ACell’s business efforts by providing clear guidelines for our employees and other stakeholders, as well as reducing our level of risk.

The Senior Manager of Professional Education will develop, manage, and drive a strong educational program in support of ACell’s existing and future products across the U.S. This individual must have a strong science background (RN, PA, RpH, etc.) and the ability to work cross functionally with the Sales, Marketing, R&D, and Regulatory departments, and other third parties such as ACell’s Key Opinion Leaders (“KOLs”).

Principal Responsibilities

  • Develop new and manage existing face-to-face and online educational programs and symposia, cadaver labs, proctorships and, as applicable, support grand rounds and physician journal club lectures
  • Lead the execution of the professional education plan, strategy, and tactics
  • Present scientific data (written and verbal) to support ACell’s educational strategy
  • Engage and support the training of Healthcare Professionals (“HCPs”), KOLs, existing and potential customers, and other clinical and non-clinical organizations and groups
  • Responsible for overseeing educational program logistics through internal and external resources
  • Collaborate with other ACell departments to execute an effective professional education program to ensure ongoing learning and, as applicable, adoption of ACell products
  • Develop and maintain collaborative relationships with KOLS, clinicians, and professional organizations
  • Work to ensure presentations are consistent with ACell’s goals and objectives and in compliance with ACell’s indications for use
  • Contribute toward the development of an annual departmental budget and annual needs assessment by forecasting future educational needs and utilizing the previous year's budget, current business objectives, and budget guidelines

Skills & Requirements

Required Education and Experience

  • Bachelor’s degree in a life sciences discipline such as nursing, physician assistant, or pharmacy is strongly preferred; advanced degree also preferred (e.g., MBA, MHA, M.A.Ed.)
  • A minimum of 5 years of experience in the life sciences industry; such experience can include a combination of clinical (nursing, pharmacy, etc.), business, and/or clinical education

Required Knowledge, Skills, and Abilities

  • Must be willing to relocate to Maryland for the position
  • Must have excellent interpersonal and presentation skills
  • Must be a team player
  • Excellent attention to detail
  • Must have a strong clinical background and the ability to communicate scientific information and data to all levels of HCPs
  • Ability to handle multiple assignments and effectively adapt to changing priorities
  • Knowledge of regulations, guidelines, and codes (e.g., the AdvaMed or PhRMA Code, Sunshine Act, etc.)
  • Must have superb organizational skills and the ability to execute within strict timelines
  • Significant experience developing curriculum and delivering science based training

Travel Requirement
Up to 25% travel


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Scientific Liaison

Date Posted:
3/2/2017

ACell

MD

The Scientific Liaison is responsible for supporting the Sales and Marketing teams with various events such as sales trainings, grand rounds, sales dinners, and national labs. The liaison will also develop and sustain relationships with surgeons, Key Opinion Leaders (KOLs), and healthcare professionals and act as a conduit of information for ACell regarding new product development initiatives, clinical research activities, and therapeutic approaches.

Principal Responsibilities

  • Attend medical conferences to stay current with industry trends and gain knowledge of the therapeutic environment
  • Respond to questions from healthcare providers
  • Deliver evidence-based scientific presentations to external customers (surgeons, KOLs, and thought leaders)
  • Provide field-based medical education on ACell products
  • Network with KOLs to keep informed on new emerging technologies, procedures, and clinical challenges
  • Serve as scientific expert to internal colleagues
  • Communicate with Sales and Marketing to ensure presentations are consistent with ACell’s goals and objectives
  • Communicate scientific information to the healthcare community to ensure awareness and proper use of ACell products
  • Support sales training to ensure up-to-date knowledge of product use and competitive climate

Skills & Requirements

Required Education and Experience

  • Ph.D. required
  • Minimum of 3 years of scientific experience in a comparable role in the medical device industry

Required Knowledge, Skills, and Abilities

  • Proven ability to effectively communicate complex scientific information
  • Excellent verbal, written, and interpersonal skills
  • Excellent public speaking skills
  • Ability to collaborate with internal colleagues in Sales, Marketing, Regulatory, and Compliance
  • Ability and willingness to work evenings and weekends
  • Must Perform all activities in compliance with ACell’s Code of Conduct and Ethics

Travel Requirement
60% travel required


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Postdoctoral Affairs Specialist

Date Posted:
3/2/2017

Van Andel Research Institute

MI

Position Description:
Van Andel Research Institute (VARI) is a leading independent biomedical research facility and is dedicated to determining the epigenetic, genetic, molecular and cellular origins of cancer, Parkinson's and other diseases, and translating those findings into effective therapies. The Institute is home to more than 330 scientists and support staff that work in on-site laboratories and in collaborative partnerships that span the globe.
VARI strives to create an environment that stimulates creativity and nurtures professionalism and our Office of Postdoctoral Affairs (OPA) is committed to maintaining the highest standards of postdoctoral training and to provide a program that prepares our postdocs for the next step in their career.

To ensure we are providing our postdoc's the best in research training, we are seeking to hire a Postdoctoral Affairs Specialist to join our OPA team.
As a Postdoctoral Affairs Specialist, your first and foremost responsibility will be to administer and assist in the development of programs, workshops, and professional development opportunities aimed at enhancing the postdoctoral training at VARI.
We also understand winning a competitive fellowship or grant is a mark of distinction in a postdoc's career progression and we encourage our postdoctoral fellows to apply for their own fellowship support during their training at VARI. As the Postdoctoral Affairs Specialist you will also play a role in identifying appropriate funding opportunities and training and writing high quality grant/foundation proposals. These applications will be from government (NIH, NSF, DoD, DTRA, etc.), private grant making foundations, and international sources.

Responsibilities:

Professional and Career Development:

  • Assisting with the planning, developing, and implementing of educational and career training programs for our postdocs.
  • Coordinate workshops, career training events, and professional development opportunities
  • Develop and maintain postdoc resource materials and content to the Office of Postdoctoral Affairs SharePoint site.
  • Assists in the recruitment efforts of postdoctoral fellows through recruiting events, recruitment materials, and networking
  • Administer the postdoc alumni database

Grant Writing and Mentoring:

  • Reviewing literature dealing with grant funds available through government/international agencies and private foundations
  • Working closely with our postdoctoral fellows and their principal investigators on strategizing and identifying appropriate funding opportunities
  • Providing advice/mentorship on policies, guidelines, and practices of relevant funding agencies
  • Facilitating our postdocs, and at times, drafting, and editing proposals
  • Ensuring timely delivery of innovative and approvable grant submissions
  • Assisting in the development of work plans and project timelines for each grant application

Qualifications:
This job might be right for you if:

  • You are motivated and driven. You take ownership of your projects. You like learning new things and advancing your skill set. If you don't know the answer, you'll dig until you find it
  • You love taking on difficult challenges and finding the best solution whether it be tried-and-true or cutting edge
  • You enjoy collaborating and working as a team. You are passionate about building relationships and have a passion for postdoc advocacy and engagement
  • You have a well-established track record of critically contributing to the preparation and able to drive the work of multiple people towards the submission of high quality, competitive grant proposals
  • You are an outstanding writer able to communicate in a compelling and succinct form
  • You have the ability to work well under pressure and perform under tight deadlines

To join our team you need to have at least:

  • A Master's degree (Ph.D. and postdoc experience preferred) in molecular/cellular biology, biochemistry, neurobiology, or other life science.
  • Career and/or professional development training experience
  • Demonstrated ability to identify appropriate scientific funding opportunities.
  • Extensive experience and demonstrated ability to write scientific proposals, publications, reports and presentations.
  • Highly proficient with MS Office and Adobe Acrobat.
  • Ability to work independently and collaboratively with a diverse workforce.

To Apply:
Interested candidates should submit a cover letter and resume as a single combined PDF file here. In your cover letter, please outline your skills and experience in digital integration and communications, your future career goals, and how these factors fit with the position described.

This position will be open until filled. If you have any difficulty uploading your application or any questions, please email Eric Miller at eric.miller@vai.org.

VAI is actively striving to diversify its workforce and strongly encourages qualified individuals from underrepresented groups to apply. Van Andel Institute is an EEO and Affirmative Action Employer.


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Bioinformatician

Date Posted:
2/28/2017

Duke Human Vaccine Institute

NC

The Duke Human Vaccine Institute and the Duke Center for HIV/AIDS Vaccine Immunology & Immunogen Discovery (CHAVI-ID), providing national and international leadership in the fight against major infectious diseases such as HIV, influenza, and malaria, are currently recruiting for a highly motivated individual to join our team. The Duke Human Vaccine Institute (DHVI) is an interdisciplinary, interdepartmental institute dedicated to the study of basic and translational science required to understand host-pathogen interactions that can be translated to vaccines against human diseases. DHVI comprises a team of highly interactive investigators that have expertise in virology, immunology, computational biology, molecular biology, microbiology and animal models.
We are seeking a candidate for the position of bioinformatician with a background in computational structural biology or sequence analysis or both. The sequence analysis-based work performed by the bioinformatician will involve developing and implementing innovative computational approaches for the analysis of large sequence datasets generated by next generation sequencing platforms, assistance in the creation of a software pipeline and database system for analyzing and cataloging antibody sequences as well as designing and implementing a high-performance computing pipeline for analyzing large-scale transcriptomics. The computational structural work performed will involve structural modeling and analysis of antibody-antigen interactions, molecular simulation, as well as the implementation of computational protein design algorithms for improving vaccine immunogen designs.

The position requires a Master’s degree in bioinformatics, computer science, computational biology, or a related field. A PhD is a plus. A minimum of five years relevant experience is required including experience in a UNIX/Linux environment, the development of computational methods and programs for the analysis of genomic and/or structural data, web-based bioinformatics tools, public domain biological databases and software tools for sequence and structural analysis. Experience with Perl or Python, R or MATLAB, web design, database systems, high performance computing environments, and statistics is also desired. Proficiency in C++ programming is highly preferred


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Senior Scientist in Microbiology, Microfluidics, Microscopy, Biomedical Engineering

Date Posted:
2/28/2017

Fluid-Screen Inc.

MA

Position Description:
Fluid-Screen, Inc. is an award winning Life Sciences startup based in Cambridge, MA. We are commercializing a technology developed at Yale University that can rapidly detect bacterial contamination that can help prevent infectious disease outbreaks and save lives in a variety of settings.
Fluid Screen's lab-on-a-chip system detects bacteria in water, blood and urine with the sensitivity of single bacterium in just 30 minutes, compared to a day or more for alternative technologies. The patented technology and the team have been recognized with the Grand Prize in the Create the Future NASA Design contest (#1 out of 900 entrants worldwide), a Gold Prize in Mass Challenge (top 1% of contenders), and more than ten other awards, the research has been published in Nature.
The company specializes in the development of rapid microbiology solutions for a range of industries including water testing, pharmaceutical manufacturing, and medical diagnostics.
The company is seeking an experienced Senior Scientist to join the team and lead R&D in our Cambridge lab space (LabCentral). The successful candidate will be highly independent, excited to design and execute research activities to develop and test our cutting-edge technology, and willing to expand capabilities in new fields. Do you envision yourself solving some of the world's most important problems? Do you thrive in a high growth, fast paced environment with access to state of the art lab facilities? If so, then this is the opportunity for you.

Experience:

Advanced Degree (PhD preferred) in microbiology or biomedical engineering, additional background in medical devices or nanotechnology a plus
Experience with optical and fluorescent microscopy
Hands-on lab experience with a broad range of methods/technologies/equipment, including: biomedical engineering or microfluidic devices
Track record with meticulous bench work and record keeping
Ability to focus on the task at hand
Strong ability to troubleshoot and problem-solve experiments
Experience with BL2 lab practices
Proven ability to design and oversee all phases of experiments
Comfort handling sensitive materials
Qualities:

Independent, self-starter that works well under minimal supervision. You will be responsible for contributing to R&D functions that play a key role on upcoming pilot studies
Strong communication. This is a must. It is essential for our team to communicate effectively to deliver complete results
Passion for bench work
Ambitious with proven leadership track record. This is a high growth opportunity with the potential to help shape the growth of our company
Comfortable in fast-paced environments. Must be able to meet deadlines
Impact Driven. Fluid-Screen was developed to make a difference in the world
Flexible. This is an early stage startup-processes and responsibilities are constantly changing
Adaptable. Always willing to help get the job done-no task too big or too small
Creative. Your unique thought processes will become key to the success of the company
Culture:
Fluid-Screen is a multi-disciplinary, tight-knit group looking to add another enthusiastic member to our team. We are passionate about our work as we truly believe it will make a difference in the world. This includes taking on responsibilities that may be completely new to you-which should be an exciting opportunity for personal growth!
Interested?

To Apply:
Please include a CV and desired compensation and email: jobs@fluid-screen.com
subject: Senior Scientist (NIH)


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Senior Medical Information Scientist

Date Posted:
2/28/2017

Fresenius Medical Care Renal Therapies Group

NC

Position Description:
The Fresenius Renal Therapies Group, a division of Fresenius Medical Care North America, is the leading provider of dialysis equipment, dialyzers, and related disposable products and a major supplier of renal pharmaceuticals in the United States. The Medical Information and Communication Office provides scientific information and professional education to healthcare providers and internal partners.

Duties and Responsibilities:

Provide excellence in medical writing of medical information and educational materials
Develop non-product related clear and concise scientific presentations and manuscripts on disease state and best treatment practices
Regularly update the existing library of educational materials based on current published evidence and proven clinical best practices in the field of nephrology and dialysis
Apply scientific expertise in daily self-dependent professional medical writing and in-depth literature searches
Keep up-to-date with and provide expertise on current applicable FMCNA and FDA legal and compliance guidances
Ensure and document compliance of medical information and educational materials for internal and external auditing
Education, Experience, and Required Skills:

PharmD., Ph.D. or MD strongly preferred
Minimum of a Master of Science degree in an allied healthcare field with a strong background in academic medical and scientific research
5 - 8 years' related experience; or a Master's degree with 3 years' experience; or a PhD without experience; or equivalent directly related work experience.
Documented strong expertise in literature evaluation, data analysis and self-dependent professional medical writing is required.
Documented strong expertise in literature evaluation, data analysis and self-dependent professional medical writing is required.
Preferably, the candidate will have publications in relevant journals and experience in presenting at medical or scientific symposia and congresses.
Expertise in Nephrology and Dialysis strongly preferred
Good understanding of the pharmaceutical industry and health care environment and its regulations
Excellent proficiency and experience in medical and scientific literature identification and evaluation
Excellent medical writing and editorial skills, validated by past work experience.
Ability to present papers and communications in the professional medical environment.
To Apply:
Please apply on-line: https://jobs.fmcna.com/job/charlotte/sr-medical-information-scientist/488/3887844
Inquiries about the position can be directed to Corinne Zeller-Knuth: Corinne.Zeller-Knuth@fmc-na.com

Application Deadline: March 31, 2017


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Director, Undergrad Research Center and External Scholarships

Date Posted:
2/28/2017

Binghampton University

NY

Job Description:
Binghamton University invites applications for the position of Director of its Undergraduate Research Center and Office of External Scholarships, Fellowships and Awards. The director oversees both offices and reports to the Vice Provost for Undergraduate Education and Enrollment. The desired starting date is July 1, 2017.

Responsibilities:

Oversee and promote existing undergraduate research/creative activity initiatives, including the Summer Scholars and Artists Program, the annual undergraduate research journal Alpenglow, the University's annual Research Days events, the Current Research Opportunity Postings (CROP), and more.
Collaborate with faculty and staff across the University to extend access to undergraduate research/creative activity opportunities, especially in the humanities and social sciences.
Represent the Undergraduate Research Center at University functions and events
Maintain, coordinate, expand and publicize a scholarship database for graduate and undergraduate opportunities
Oversee numerous selection committees for University, as well as nationally/internationally competitive scholarships and awards
Mentor and support undergraduate and graduate students in preparation for their application to national and international scholarship competitions (e.g. Goldwater, Truman, Udall, Gilman, Rhodes, etc.)
Work with students and faculty to identify and support applicants for Fulbright scholarships
Collaborate with faculty and staff across the University to identify and recruit students who would make good scholarship candidates
Oversee and expand all communication (including social media) and programming efforts to help students who are interested in participating in undergraduate research/creative activities, both on-campus and off-campus
Oversee and expand all communication (including social media) programming efforts to encourage students to participate in scholarship competitions
Work with the University's various communications outlets to celebrate student accomplishments
Identify grant opportunities to promote undergraduate research/creative activities and work collaboratively with faculty to write grants for undergraduate research/creative activities
Assess the impact of research and scholarship initiatives by designing appropriate evaluation instruments
Requirements:

Candidates must demonstrate a strong understanding of scholarship, a commitment to high-quality undergraduate education, and experience in the recognition of high academic achievement
Candidates must show evidence of effective academic mentoring
Master's degree in a STEM or liberal arts discipline
Excellent written and oral communication skills are required, along with a demonstrated ability to work with a wide range of constituencies, including scholarship and fellowship agencies, faculty groups, administrators and students.
Excellent organizational and time-management skills
Ability to work under pressure to meet deadlines
Ability to independently manage and coordinate activities in a complex environment, to think critically and creatively, and to direct a team effectively to accomplish new initiatives
Availability to work occasional evenings and weekends
Strong research and analytical skills; ability to understand and synthesize information from a wide variety of disciplines
Demonstrated problem-solving and negotiation skills
Ability to administer multiple programs with attention to detail
3-5 years of experience working with undergraduates in a higher education setting
Administrative experience, including managing a budget and supervising other employees
Preferred Qualifications

Ph.D. in a STEM or liberal arts discipline
Previous experience with the National Association of Fellowships Advisors and with students applying for prestigious fellowships
Previous experience directly mentoring students in undergraduate research
To Apply:
Review of applications will begin immediately and continue until the vacancy is filled.
Persons interested in this position should apply online.
Please submit:

CV,
Cover letter, and
Contact information for three professional references
You may add additional files/documents after uploading your resume. After you fill out your contact information, you will be directed to the upload page. Please login to check/edit your profile or to upload additional documents: http://binghamton.interviewexchange.com/login.jsp


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Associate Director for Actionable Science

Date Posted:
2/28/2017

University of Maryland

MD

Position Description:
Reporting to the Director of Social Science and Policy, the Associate Director for Actionable Science will provide support for interdisciplinary synthesis research teams conducting long-term (2-year) projects, workshop participants, and individual visitors. He/she will work with SESYNC participants across the lifespan of their projects and be responsible for helping them with both scientific aspects and identification of potential decision contexts for the problems being addressed. She/he will: provide direct feedback and advice regarding opportunities to develop actionable products and outcomes from the research conducted; help link participating researchers to existing and new networks of decision makers as appropriate; and help identify relevant strategies to engage individuals from government agencies, non-governmental organizations, and the private sector in SESYNC's research teams and other activities. As research products emerge he/she will work closely with researchers to determine how scientific products may be conveyed into ongoing or new decision-making contexts. The Associate Director for Actionable Science is expected to maintain and expand an extensive network of contacts in the policy arena to learn about key science needs across the spectrum of socio-environmental problems. The incumbent will also write and edit materials for a variety of venues, participate in the review of projects and the overall evaluation of Center programs, and routinely brief the rest of the SESYNC leadership on researchers' progress.

Minimum Qualifications:
MS or MA with a background in environmental decision-making and policy and a minimum of 2 years' experience in a position focused on bridging scientific knowledge to audiences outside the research community. A background in environment-related social or natural science and the ability to understand complex scientific problems and approaches needed to address them. Experience serving groups of researchers as a liaison, sounding board, and connection to other disciplines and audiences. An existing network of relationships in environmental agencies, NGOs, and business groups - and willingness to expand those networks. Strong organization skills and the ability to initiate and manage a portfolio of multiple and diverse projects. A professional demeanor, exceptional written and oral communication skills, and desire to actively engage with a wide variety of individuals both at the Center and in wide ranging policy and decision-making networks. Demonstrated ability to deliver timely outcomes as a member of a support team (and independently). The successful applicant should be able to work in a dynamic environment and have the flexibility to adapt to the changing needs of research teams.

Preferences:
Ph.D. in a relevant discipline. Experience working outside of academia and/or a research environment. Experience with group facilitation and experience in program evaluation. Examples of specific written (print and/or web based) products developed to translate complex scientific outcomes for non-peer audiences.

To Apply:
Preference will be given to applications received by March 30, 2017. Please submit cover letter, resume, and three professional references to this webform for consideration. For questions, please email research@sesync.org.

 


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Neuropsychologist

Date Posted:
2/24/2017

Southern Maine Health Care

ME

Neuropsychologist

Southern Maine Health Care

Kennebunk, ME

40 hours/week, Day Shift

 

This position is responsible for performing comprehensive neuropsychological evaluations, diagnosis and specialized psychological interventions for a pediatric, concussive, transition and developmentally delayed patient population. These patients are at risk for, or are demonstrating, developmental, cognitive, behavioral and emotional disorders which cause difficulty navigating the requirements of school, work and relationships. This position will provide assessment, diagnosis, treatment plan development, and individual and family interventions as part of the Center for Developmental Medicine’s multi-disciplinary team.

 

The Neuropsychologist will work closely with the Developmental Pediatrician, the Developmental Behavioral Health Nurse Care Manager, the Behavioral Health Integrated Clinician and the Neuro-Assessment Clinic Coordinator/Psychometrist. The Neuropsychologist will collaborate with the Neuro-Assessment Clinic Coordinator/Psychometrist on all neuropsychological evaluations. This position has the future potential of participating actively in an educational mission, which may include supervision, teaching, and consultation with psychology trainees, psychiatry residents, medical students, and other trainees.

 

Required Minimum Knowledge, Skills and Abilities:

  • Licensed as a Psychologist by the Maine Board of Examiners of Psychologists.
  • Certification with the American Board of Clinical Neuropsychology or the American Academy of Clinical Neuropsychology preferred.
  • Board certification or eligibility for certification in clinical neuropsychology by the American Board of Clinical Neurology/American Board Professional Psychology.
  • A minimum of two years of clinical experience providing neuropsychological services by employingprocedures of neuropsychological evaluations, assessments, diagnostic tools, case formulations and therapeutic treatment planning.
  • Advanced skills in neuropsychology evaluation, treatment, and consultation acquired through the completion of a doctoral program, all required pre-doctoral, internship, and postdoctoral training, accredited by the American Psychological Association, or equivalent, as recognized by the Maine Board of Examiners of Psychologists.
  • Expert knowledge of lifespan developmental psychology, the applied science of brain-behavior relationships and pediatric, concussive, transition and developmentally delayed populations required.
  • The ability to integrate neuropsychological and clinical psychometric findings with neurologic, medical, biopsychosocial and behavioral data and interpret these findings with an appreciation for familial, social, cultural and ethical issues.
  • Essential personal, professional, and interpersonal skills required toexpress thoughts clearly, respectfully and effectively both verbally and in writing, to conduct neuropsychological evaluations and interventions with patients and their families and to function collaboratively and effectively as a member of the health care team.
  • Flexibility of personality necessary to respond to changing circumstances and priorities and detail oriented with outstanding time management and organizational skills.

 

To apply, please visit: http://www.careersatmainehealth.org/job/7010456/neuropsychologist-kennebunk-me/

 

About Southern Maine Health Care

The award-winning Southern Maine Health Care (SMHC) system includes a multi-specialty physician group and a full-service medical center in Biddeford (including a special care unit and York County’s only inpatient mental health unit). Located in York County, Maine, our system provides emergency care, surgical services, and diagnostic and therapy services at SMHC’s Biddeford Medical Center, as well as Walk-In Care centers, a birthing suite, cancer care, pain management, centers for breast care and sleep disorders, eldercare services, rehabilitation programs, preventive/wellness services, community education and support programs.

 

At Southern Maine Health Care, you’ll find the best of both worlds: the friendliness and natural beauty of southern Maine, and the opportunity to work with the best resources and technology healthcare has to offer. Our organization and staff play an integral role in improving the health of the people in the communities we serve through volunteerism and outreach programs. As a member of the MaineHealth system, SMHC offers a breadth and depth of services, facilities and training that provide opportunities for both personal and professional growth.

 

MaineHealth values diversity and is an Equal Opportunity/Affirmative Action employer. Federal and state laws prohibit discrimination in employment because of race, color, national origin, religion, age, sex, sexual orientation, disability or veteran status.


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Consultant

Date Posted:
2/24/2017

Alacrita

MA

About Alacrita

Alacrita is a rapidly growing life science consulting firm with offices in London and Boston delivering strategic, analytical and operational support to the world’s leading biotech, pharma and life science companies.

Location

Cambridge and Waltham, MA

About the job

We have an exciting opportunity for an enthusiastic, entrepreneurial hard-worker to help us serve our clients more efficiently.

This is an entry level position into the international life sciences field (Intern), but we will also consider people with up to two years of relevant life science experience (Consultant Analyst).

Your job will be wide ranging and intellectually stimulating. You will have exposure to some of the most exciting, cutting edge biological science that is being developed by the biotech and pharmaceutical industry. You will work closely with the senior team in Boston and will have an opportunity to grow within Alacrita.

You will think like an entrepreneur. Our clients have diverse unmet needs and each unmet need represents an opportunity for us. You will be tuned to identify these needs and we will work with you to incorporate solutions to them into our service offering. We’ll share the arising financial rewards with you.

In time, you will take on more responsibility, with opportunities to represent Alacrita at international industry conferences and play a more prominent role on our consulting assignments.

Who we're looking for

We need a sharp, intelligent, entrepreneurial life sciences graduate (PhD or MD preferred, but MS or MBA with industry experience also considered) who has the drive and determination to succeed in a rapidly growing professional services firm. Prior experience of business development, technology transfer or another business-oriented function in the life science sector is preferred. Ideally, you have a basic understanding of the drug development process and emerging therapeutic technologies.

In addition you:

Are personable, with the ability to quickly strike up a rapport with strangers
Show a high degree of precision in thinking and communicating
Can encapsulate ideas and concepts in concise, well written English
Highly numerate, and comfortable with complex spreadsheets
Have excellent attention to detail and orientation toward meticulous work; strong organizational skills
Are able to exercise discretion and maintain confidentiality
Are able to project and maintain a professional and positive attitude


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Postdoc Test Development

Date Posted:
2/24/2017

The Childrens Hospital of philadelphia

PA

Conduct independent scholarly research and develop new methods and protocols
Participate in project planning, recording and evaluation of data
Acquire technical, lab management and grant writing skills
Participate in seminars, lectures, poster sessions and presentation at national meetings
Supervise junior lab members
Assist with other research projects
Required Licenses, Certifications, Registrations
Required Education And Experience
A terminal degree PhD, MD, DVM, etc.
According to the CMS (Centers for Medicaid and Medicare Services) a copy of diploma or transcript is required as proof of academic achievement for all non-laboratory personnel performing non-waived POC testing
The training and qualifications of all personnel trained outside of the US must be reviewed to ensure that it is equivalent to CLIA requirements, with records of the review available on-site. The equivalency evaluations should be performed by a nationally recognized organization.


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Postdoc Neuroscience Early Discovery Job

Date Posted:
2/24/2017

Merck

MA

Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. Today, we are building a new kind of healthcare company – one that is ready to help create a healthier future for all of us.
Our ability to excel depends on the integrity, knowledge, imagination, skill, diversity and teamwork of an individual like you. To this end, we strive to create an environment of mutual respect, encouragement and teamwork. As part of our global team, you’ll have the opportunity to collaborate with talented and dedicated colleagues while developing and expanding your career.
Be a part of the legacy: MRL Postdoctoral Research Fellow Program
The Merck Research Laboratories (MRL) Postdoctoral Research Fellow Program aims to be a best-in-industry program for postdoctoral researchers, designed to provide you with an academic focus in a commercial environment. With the resources, reach, and expertise of a large pharmaceutical company, postdoctoral researchers will be positioned to excel in an institution committed to breakthrough innovation in research and discovery to improve human health.
Position Overview
A recent and rapidly emerging body of work in Alzheimer’s Disease (AD) has shifted scientific emphasis increasingly toward innate immune pathways and have therefore implicated microglia as a key cellular determinant of human AD pathophysiology. As a postdoctoral fellow in the Neuroscience Early Discovery Unit (Boston), you will be part of a community of postdoctoral fellows working across different departments and with academic collaborators as well. You will collaborate closely with a team of scientists who possess diverse scientific backgrounds – from neuroscience, pharmacology, genetics, proteomics and other drug discovery disciplines. Support for you or your projects will not be the limiting factor. Your project will focus on (i) establishing human iPSC derived microglia, (ii) establishing disease modeling assays using these cells, and (iii) collaborating on various molecular profiling projects with collaborators. You will be responsible for conceiving, designing, planning and executing experiments independently, but you will work within an integrated team already active in this space. You will also have the opportunity to see how a deep understanding of biology contributes to the drug discovery process.
Responsibilities Include But Are Not Limited To
Lead the development and implementation of cellular models of human and/or primary rodent microglia support functional and genomic insights into neurodegenerative disease.
Work with the scientific mentor to establish near and long-term goals, both scientific and professional.
Analyze, interpret and communicate data in a timely manner to the postdoctoral mentor (and collaborators) to drive data-driven decisions and scientific prioritization insights.
Present your research at internal and external scientific meetings, including publishing in peer-reviewed journals.
Qualifications
Education Minimum Requirement:
PhD in Neuroscience, Cell Biology, Bio-engineering or related discipline with 3 years or less of postdoctoral experience or met all the requirements for a PhD by May 2017
Required Experience And Skills
A solid foundation in cell biology, biochemistry and molecular biology will be central to the postdoctoral work.
Established skills in culturing and expanding induced pluripotent stem cell (iPSC) lines; Ideal (but not required) is experience using macrophage/microglia differentiation protocols. Alternatively, experience with primary microglial and neuronal culture and/or organotypic ex vivo slice methods will be considered.
Experience with in vitro (or ex vivo) high content imaging. The ideal candidate also possesses background with automated imaging platforms, flow cytometry and/or FACS/MACS cellular sorting.
Soft skills include a track-record of working flexibly between independent goals and collaboratively within teams, as well as being a clear communicator to enable synergies between individuals.
Strong track record of publication in peer-reviewed journals..
Preferred Experience And Skills
Knowledge of neurodegenerative diseases and genetics is a plus, but training will be provided.
General expierence or understanding of various molecular profiling platforms, in particular RNA-seq/Next-generation sequencing platforms (or quantitative proteomics).
Background in automated image analysis of high-content imaging.
Our employees are the key to our company’s success. We demonstrate our commitment to our employees by offering a competitive and valuable rewards program. Our Company’s benefits are designed to support the wide range of goals, needs and lifestyles of our employees, and many of the people that matter the most in their lives. If you need an accommodation for the application process please email us at staffingaadar@merck.com.
Search Firm Representatives Please Read Carefully
Merck & Co., Inc. is not accepting unsolicited assistance from search firms for this employment opportunity. Please, no phone calls or emails. All resumes submitted by search firms to any employee at Merck via email, the Internet or in any form and/or method without a valid written search agreement in place for this position will be deemed the sole property of Merck. No fee will be paid in the event the candidate is hired by Merck as a result of the referral or through other means.


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Equity Research PhD fellowship

Date Posted:
2/24/2017

Goldman Sachs

NY

Job description
Goldman Sachs Firm Overview
The Goldman Sachs Group, Inc. is a leading global investment banking, securities and investment management firm that provides a wide range of financial services to a substantial and diversified client base that includes corporations, financial institutions, governments and high-net-worth individuals. Founded in 1869, the firm is headquartered in New York and maintains offices in London, Frankfurt, Tokyo, Hong Kong and other major financial centers around the world.
Divisional Overview
Global Investment Research (GIR) provides investment recommendations by generating fundamental research and analysis of companies, industries, markets and economies. GIR analysts help our clients achieve superior returns through our creative, differentiated investment insights and ideas. Our clients include mutual funds, hedge funds and pension funds, among others.
The Fellowship
Goldman Sachs is seeking PhD candidates or graduates with non-finance backgrounds to participate in a 6 month fellowship. The Fellowship will enable PhDs to explore a potential career transition into Equity Research. The Fellows are provided with training and hands-on experience on a research team as well as networking and mentorship opportunities.
Is open to PhDs in math, technology, or science related disciplines
Does not require finance experience however, an interest in investing or a basic knowledge of the markets is helpful.
Sample Responsibilities
Build and maintain financial models
Market share, macro trend, and cross company and sector data analyses
Company specific projects
Update monthly reports, marketing books, and weekly reports
Update and maintain daily valuation sheets? Excellent verbal and written communication skills
Meticulous attention to detail and strong organizational skills
Exceptional analytical skills, lateral thinking, and judgment
A proactive approach and a high level of enthusiasm
Experience with Microsoft Office applications (Excel, Word, Outlook)
Ability to meet aggressive deadlines


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Scientist I

Date Posted:
2/24/2017

The Children's Hospital

PA

Principal contributions are scientific or intellectual, characterized by originality and creativity. Works under the mentorship of an established principal investigator to conduct research in a specific scientific area. Initiates and conducts independent experiments without direct supervision. Develops own research project with the guidance of the principal investigator. Develops new experimental procedures and hypotheses for further investigation. Prepares manuscripts and abstracts for publication. Publishes scientific articles in refereed journals. Collaborates and interacts with other researchers within the institution and at other institutions. Assists in the preparation of scientific publications and research grant proposals. Serves as resource person for colleagues and as a mentor for less experienced research personnel. May manages/supervises other research staff or projects; assists with the management of laboratory operations.
Job Responsibilities
Conducts research of significant scientific value in the basic and/or translational science area(s) relevant to their practice specialty
Participates in the design, planning and conduct of one or more experiments
Trains technical staff, students, fellows & physicians in lab procedures
Monitors daily resource allocations and day-to-day lab personnel activities
Composes/Assists in developing publications for peer reviewed, scientific, quality and management, Journals
Assists with the submission of applications for grants/contracts for funding of research projects
Collaborates with researchers, external agencies and institutions to develop cooperative research initiatives
Responsible for appropriate use of research funds
May supervises technical staff and students
May participates in educational programs and teaching assignments
Job Responsibilities (Continued)
Job Responsibilities (Continued)
Required Licenses, Certifications, Registrations
None
Required Education And Experience
0-2 years scientifically relevant post-fellowship experience
MS with 6-8 yrs. scientifically relevant experience
100% of their effort is funded by Principal Investigator(s) grants
Preferred Education, Experience & Cert/Lic
Terminal degree (MD, PhD, DVM) Post-Doctoral fellowship experience preferred


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Technical Services

Date Posted:
2/24/2017

Promega

WI

Promega, an international biotechnology company, is seeking a Technical Services Scientist 1 to join our team. This person will learn and provide technical support (verbal and written) to both customers (internal and external) on Promega’s products, related applications and document information into database.

Our ideal candidate will have:

B.S/M.S/PhD in molecular biology, cell biology, protein biochemistry or related area
Minimum 3 years lab experience and proven knowledge and understanding of core applications of molecular biology, cell biology and or/protein biochemistry.
Ability to discuss fundamentals, principals, and technical theory of experimental design, techniques and results in a clear and concise manner.
Excellent communication and listening skills, both verbal and written.
To apply, view a complete job description, and learn more about our company, please visit:

https://careers-promega.icims.com/jobs/1353/technical-services-scientist-1/job

Only applications received through our website will be considered.


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Staff Scientist

Date Posted:
2/24/2017

Baylor

TX

The Center for Drug Discovery is a strategic research center established at Baylor College of Medicine within the Texas Medical Center in Houston. The mission of the Center for Drug Discovery is to establish novel discovery technologies that enable rapid and cost effective drug discovery within the academic community. We are seeking a highly skilled and motivated scientist with expertise in organic synthesis, medicinal chemistry, and/or protein sciences to join the Center for Drug Discovery. Central to our vision is the establishment of a small molecule discovery technology using a DNA-encoded chemistry approach. The team, led by scientists with drug discovery experience in academia and the pharmaceutical and biotech industry, is looking to recruit additional chemists, chemical biologists, and biochemists.
Participate in early stage drug discovery efforts in collaboration with biological scientists throughout the academic community, with a goal of bringing new treatments to patients with unmet medical needs.
Participate in the design and synthesis of drug-like small molecules.
Contribute to multidisciplinary lead-finding project teams with the responsibility of hit selection and compound resynthesis for in vitro and in vivo testing. If the applicant has biochemistry or molecular biology experience, work directly with our existing biochemists and biologists to develop selection strategies and tools to enable library interrogation and perform DNA sequencing
Employ safe lab practices.
Maintain research records and laboratory notebooks.
Set up and execute a variety of organic chemistry reactions.
Perform routine purification of intermediates and final products utilizing techniques such as HPLC and other related methods.
Characterize compounds using analytical instrumentation such as LC/MS and NMR.
Qualifications
Education: PhD in medicinal/organic chemistry, chemical biology, biochemistry, or a related discipline. Significant predoctoral and/or postdoctoral experience in organic synthesis, medicinal chemistry, and/or protein biochemistry. Skill sets for the chemist/chemical biologist applicant:
Familiarity with techniques associated with medicinal chemistry, including the synthesis, purification and characterization of chemical compounds.
Excellent written & oral communication and interpersonal skills.
Knowledge of safety protocols and use of protective equipment.
Demonstrated team-worker who possesses excellent problem solving capabilities and can work efficiently with minimal supervision.
Qualified individuals will be technically independent in the set up and execution of organic reactions, as well as the purification, characterization, and identification of products.
Expertise in a variety of biochemical and cell-based assay platforms.
Experience with protein production including multiprotein complexes in bacterial, baculovirus and mammalian expression systems.
Practical experience in DNA-encoded library selection and protein characterization pertinent to small molecule drug discovery highly preferred.
Knowledge of expression platforms, purification systems and analytical techniques (e.g., Wave bioreactor, AKTA, HPLC/MS, TFF).
Familiarity with the development of higher throughput methodologies and automated technologies for protein purification, affinity selection and library sequencing.
The candidate should have a strong desire to learn new techniques and the ability to incorporate new methodologies into their work. The ideal candidate will be self-driven, resourceful, very organized and focused, and enjoy working in a dynamic team environment.


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Business Development

Date Posted:
2/24/2017

Progenera

PA

Progenra is a biotech company developing innovative new drug candidates by targeting ubiquitin pathway with broad therapeutic focus www.progenra.com . We are interested in recruiting a scientist for Business Development position. We believe that a strong science background and especially with knowledge in Cell and Mol Biology and translational medicine is a real asset. We plan to train a person with science background and strong communication skills to grow in this position.

Ph.D degree in Life Sciences required but not essential

Responsibilities

  • Learn to prepare strategic plans for marketing Progenra technologies and compounds.
  • Participate in developing drug target presentations.
  • Assist in negotiation and securing partnerships agreements and feasibility studies and followed by contract
  • Learns about new technologies and presents to internal and external customers
  • Learns new CRM and approaches new customers to introduce company technologies and drug targets
  • Data mining of pharma and biotech industry to communicate with drug discovery scientists
  • General
    • Record of accomplishment in research and publication
    • Knowledge of drug discovery trends and technologies


Skills

  • Evidence of ability to learn drug discovery systems and apply to ubiquitin pathway as therapeutic targets
  • Must be able to communicate effectively with pharma and biotech customers
  • Communication skills necessary to make scientific presentations, conferences and industry groups


Minimum of 0-5 years of experience in life sciences research labs in the pharmaceutical industry.
Compensation is dependent on experience and level of training http://progenra.com/career/ 


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Applications Scientist = MALDI

Date Posted:
2/24/2017

Shimadzu Scientific Instruments

MD

Shimadzu Scientific Instruments is one of the largest suppliers of analytical instrumentation, physical testing, and environmental monitoring systems in the world. Our products include Gas Chromatographs, Liquid Chromatographs, Mass Spectrometers, Total Organic Carbon Analyzers, UV-Vis Spectrometers, Fluorescence, Atomic Absorption, IR, X-Ray, and Universal Testing Machines. In 1975, SSI Corporate Headquarters was established in Columbia, Maryland and we currently have nine regional offices coast to coast.
Position Summary
The individual in this dynamic, team oriented position is responsible for providing real world applications solutions and high-level technical support for Life Science related products such as Biotech, MALDI....This Applications Scientist position requires exceptional communication and coordination skills, working closely with the customers, product managers, marketing and sales persons to drive sales and marketing opportunities. He/she must have hands-on experience with Biotech and MALDI instruments to provide applications development, sample analysis, training and demonstration.Also expected to prepare and present scientific material in support of marketing and sales at seminars and scientific conferences. This position focuses more on the end user desired applications and problem solving incorporating any of Shimadzu product lines to that end.
This position is to provide application solutions to promote the marketing and sales of Biotech products in the broad field for qualitative and quantitative purposes.
Job Functions Include, But Are Not Limited To
Assist with customer and research sample preparation.
Run customer samples and provide analysis reports to customers.
Provide demonstration and presentation of LC-MS and LC-MS/MS products to customers to support the sales effort.
Provide demonstration and presentation of Bio, LC-MS, LC-MS/MS products to customers to support the sales effort.
Provide demonstration and presentation of Spectroscopy products to customers to support the sales effort.
Provide demonstration and presentation of Protein Sequencer to customers to support the sales effort.
Develop application notes and other technical documents to support the sales and marketing effort.
Provide training, telephone, web and on-site technical support of LC-MS and Bio products.
Perform applications work as required to fulfill specific customer"s and collaborator"s needs.
Present technical marketing presentation at conferences, trade shows and at selected institutions.
Obtain market competitive information for LC-MS and Bio products and assist in its analysis for the sales force.
Cooperate with Shimadzu Subsidiaries worldwide.
Must travel overnight and drive, as the position requires both domestically and internationally.
Prepare monthly reports to include lab activities, research results and market related issues.
Provide technical support to customers by phone, email, webinar and on-site visits.
Prepare and/or review marketing materials as required.
Assist with all other duties as assigned.
Scope
This position"s primary focus is to provide technical expertise and applications development to our customers, sales force, technical support and service personnel of Life Science Products to ensure that Shimadzu meets or exceeds its goal and objectives. This person must be the expert in all facets of application fields using Life Science products for qualitative and quantitative analysis.
Requirements
KNOWLEDGE REQUIREMENTS:
CASUAL
WORKING
THOROUGH
Japanese culture
Shimadzu products
Chemistry
Sample Techniques
Biotechnology
Computer skills
HPLC/LC-MS Hardware/Software
Applications Development
Customer Relations
Organizational and Presentation Skills
FPLC
Spectroscopy Applications/Hdw/Sw
Problem Solving Requirements
The individual in this position is required to solve complex problems within limited time frame with technical proficiency, scientific creativity and independent line of thought. The position requires extensive troubleshooting and isolation of variables in a methodical and efficient manner to solve customers and regional problems.The ability to work with a diverse group while allocating limited resources effectively.
Education And/Or Experience Requirements
Having passion on science and bench work, the individual in this position must have comprehensive expertise and hands-on experience on every aspect of LC-MS applications in qualitative and quantitative analysis. Thorough understanding of modern mass spectrometry and chromatography is required. He/she has to demonstrate a proven record of being a fast learner, excellent communicator and thoughtful team builder.
Incumbent must have at least a MS Degree in Chemistry (or a closely related field) while a Ph.D. is highly preferred. With Ph.D. degree, 2-5 years" experience is necessary; with MS degree, 5-10 years" experience is required.Marketing and/or business experience within a manufacturing or distribution business in chromatography and mass spectrometry a big plus.
Equal Opportunity Employer/Protected Veterans/Individuals with Disabilities.
Please view Equal Employment Opportunity Posters provided by OFCCP here.
The contractor will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, or (c) consistent with the contractor"s legal duty to furnish information.
Shimadzu Scientific Instruments is an Equal Opportunity / Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, or protected Veteran status.


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Product Development Scientist

Date Posted:
2/24/2017

Personal Genome Diagnostics

MD

We are currently seeking extraordinary, highly motivated individuals to join our research and development team, with a focus on tissue and cell-free DNA liquid biopsy approaches. The successful candidate will develop and optimize cutting-edge diagnostic technologies for use as an IVD. Background in product development for Class II and III assays is preferred. Expertise in design control desired.

Core Qualifications:

Master’s or Ph.D. Degree in Biology or Related Field with a minimum of 1-3 years’ experience in molecular diagnostics or medical device industry
Experience in 510k, PMA submissions, and FDA interactions preferred
Design control, verification and validation protocol expertise required
Expert knowledge of scientific principles and concepts
Oncology and/or diagnostics experience strongly preferred
Experience with next-generation sequencing technology and bioinformatics analyses of cancer strongly preferred
Cross-functional experience working with product development teams


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Senior MR Scientist

Date Posted:
2/24/2017

Siemens

MD

The Magnetic Resonance (MR) Research Collaborations Group has an immediate opening for a senior scientist with a focus on pulse sequence development, image reconstruction and collaboration management.
Position Overview
The Siemens MR R&D team in the US is a multidisciplinary group of highly motivated scientists, engineers, and advanced application specialists based at various locations across the country, and working closely with our research partners at Universities and academic hospitals.
We are seeking a highly motivated and experienced individual to join our team to help maximize the clinical and business impact of our research work. The position will be based at a leading academic institution in Baltimore, MD, and will report to the MR Zone Research Manager for the Maryland and Washington DC Region. The individual will be responsible for driving innovative and clinically relevant MR techniques from prototype to a commercially available product. The individual is expected to take a lead in design, implementation, and execution of research projects in MR in collaboration with our academic and clinical partners.
Furthermore, the individual will act as a liaison between Siemens’ research collaborators and Siemens’ internal groups worldwide, including, but not limited to R&D, product definition and development teams, and Marketing.
Strong expertise in clinical applications of MR and its physical principles and understanding of how an MRI scanner works is required. Substantial experience in C++/C# software development and design of MR pulse sequences and image reconstruction using the Siemens SDE platform (IDEA/ICE) is expected. Strong attention to detail, outstanding communications skills, ability to create new and innovative solutions, establish and maintain relationships with a variety of people in different roles / levels and physical locations are critical. An outstanding track record of peer reviewed publications is highly desired.
Responsibilities
Duties will include but are not limited to the following areas:
Collaboration Management
Develop and manage the research collaboration with your academic partners.
Define and execute research projects with your academic partners to generate scientific results that are relevant for the academic and industrial partnership.
Adhere to Siemens’ collaborations policies, and take ownership of the processes for collaboration management with your assigned partners.
Research and Development
Work closely with your academic partners to drive MR research and translate this knowledge into MR products.
Drive the development of novel, clinically relevant techniques (MR pulse sequences and image reconstruction) with our research partners.
Develop and release prototypes of novel techniques in compliance with highest source code quality.
Evaluate prototypes, and publish results in peer-reviewed journals.
Conduct original research resulting in patent applications.
Educate R&D and Applications colleagues on clinical research issues.
Product Development
Product integration of innovative techniques according to quality standards for medical devices.
Implementation of improvements to currently existing product features.
Maintenance and improvements of existing code base, bug fixing, testing.
Contribute to product protocol development for novel features.
Sales and Marketing Support
Provide content for articles for Siemens publications such as MAGNETOM Flash together with internal and external collaborators.
Support educational meetings, tradeshows, and site visits.
Answer questions from Sales and Marketing related to areas of the team’s responsibility.
Demonstrate strong knowledge of organization's business practices, issues faced, and contribute to problem resolution of those issues.
Required Knowledge/Skills, Education, And Experience
Ph.D. in Biomedical Engineering / Electrical Engineering / Biomedical Physics / Imaging Physics, or equivalent.
Strong collaboration skills and ability to thrive in a dynamic environment.
Strong background in MR physics and pulse sequence design.
Expertise in MR imaging techniques and clinical applications.
Experience in working with internal and external partners.
Substantial experience in C++/C software design, implementation and coding.
Experience using Matlab for signal and image processing.
Outstanding writing, presentation, and communication skills.
Excellent teaching skills and a proactive can-do attitude.
Ability to work independently and prioritize work.
Ability to multi-task and follow through.
Detail-oriented and organized.
Skilled in MS office software applications (PowerPoint, Word, Excel).
Ability to travel up to 30%
Preferred Knowledge/Skills, Education, And Experience
Prior experience working on Siemens’ MR systems in pulse sequence design and image reconstruction is highly desired.
:


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Chemist/Scientist

Date Posted:
2/24/2017

Provatohr

VA

Job Description:
Seeking a candidate with 1-5 years of experience, preferably working in a lab or just out of a lab, to provide Scientific and Engineering support to the Defense Advanced Research Projects Agency (DARPA).

Ph. D. - level chemist with a focus in areas such as synthetic organic chemistry, polymer chemistry and/or physical organic chemistry. Specific expertise is desired across areas such as sequence-based polymer synthesis and characterization, development and use of continuous flow technologies for chemical synthesis, and applications of synthetic methodologies to applied challenges such as computing.

Required Experience:

Synthetic organic chemistry experience
Sequence-controlled polymers, aptamers, etc.
New synthetic methodologies such as flow chemistry
Physical organic chemistry
Desired Experience:

AAAS Member (http://www.aaas.org/) in Chemistry
Strong communications skills, both written and oral
Team-centric approach problem solving
DoD related RDT&E experience.
To Apply:
Please contact Everald Foster, lead recuiter for Provato, Inc. (efoster@provatohr.com) for more information and how to apply.


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R&D Associate

Date Posted:
2/20/2017

Limelight Bio

PA

Limelight Bio is an emerging biotech company developing new approaches to gene therapy that greatly expand the utility of clinically-validated AAV technologies. Our mission is to enable the treatment of debilitating inherited diseases that cannot be addressed by current methods; such as those caused by mutations in large genes and autosomal dominant inheritance patterns. Limelight was founded by experienced scientific leaders from the University of Pennsylvania, including Jean Bennett, a pioneer in research into cures for inherited blindness. The company is backed by Apple Tree Partners, a leading life science venture capital firm.

We are seeking talented individuals with a passion for biotech R&D and/or operations to advance the mission of the company. Candidates should be based in the Greater Philadelphia area.

Requirements:

  • PhD or MD in a field related to biotechnology; business and/or operations experience desired but not required
  • Minimum 2-3 years relevant work experience 
  • Ability to work independently and collaboratively in a team environment
  • Outstanding communication and presentation skills (verbal and written)
  • Excellent time management skills and ability to prioritize projects and adhere to tight deadlines under pressure
  • Prior experience working with AAV or other gene-therapy based approaches desired but not required

Salary and title to be commensurate with experience.  

About Apple Tree Partners:

Apple Tree Partners (ATP) is a New York-based life sciences venture capital firm with headquarters in Manhattan and satellite offices in Cambridge, Los Altos and Princeton. The firm has $1.61 billion under management, and is actively investing its fourth fund, with $1.5 billion in commitments. Approximately two-thirds of the fund will be invested in biotech and pharmaceuticals. ATP considers investments at all stages, from discovery research through to commercialization, the principal focus of the firm’s biotech and pharmaceuticals practice is on early-stage projects. Learn more about ATP and our portfolio at www.appletreepartners.com

About Limelight Bio:

Limelight Bio is a Philadelphia-based company developing novel gene therapies that greatly expand the utility of clinically-validated AAV vectors by enabling the treatment of diseases caused by large genes that exceed the payload capacity of AAV; or by autosomal dominant inheritance patterns that cannot be addressed using traditional gene replacement approaches.


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Senior Bioinformatics Scientist, Clinical Molecular Diagnostics

Date Posted:
2/20/2017

Personal Genome Diagnostics

MD

Senior Bioinformatics Scientist, Clinical Molecular Diagnostics 

Overview:
PapGene, Inc. is a Baltimore-based molecular diagnostics company commercializing high-complexity tests for the early detection of cancers. PapGene’s core technology uses innovative massively parallel sequencing (MPS) techniques invented by world-leading cancer researchers at Johns Hopkins University. PapGene is seeking a Senior Bioinformatics Scientist with significant computational experience to join our growing team.

Essential Duties:
The Senior Bioinformatics Scientist will develop, automate and implement DNA sequencing analytic tools in collaboration with our clinical assay team. The successful candidate will lead the implementation, execution and documentation of data analysis pipelines and workflows.

Specific Responsibilities: 

  • Develop, enhance and automate analysis of high quality DNA sequencing data in a CLIA- certified lab environment.
  • Manage modifications to MPS data analysis pipelines and train lab staff on the use of relevant bioinformatics software and tools.
  • Assist with supervision and training of Junior Bioinformatics Scientist.

Requirements: 

  • PhD in Bioinformatics, Computational Biology/Computer Science or a related area with a deep knowledge of at least one compiled programming language (preferably C#).
  • Professional level work experience with next generation sequencing data using common NGS tools as well as experience developing novel data analysis tools.
  • Creative, independent, well organized, collaborative, and solution oriented.

To be considered for this position, please forward a copy of your resume to hr@papgeneinc.com and include a cover letter explaining why you think your background is a good fit with this job description.


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Scientist I

Date Posted:
2/19/2017

Bristol Myers Squibb

CA

Bristol-Myers Squibb is a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases.
One shared journey is moving us forward at Bristol-Myers Squibb. Around the world, we are passionate about making an impact on the lives of patients with serious disease. Empowered to apply our individual talents and ideas so that we can learn and grow together. And driven to make a difference, from innovative research to hands-on community support. Bristol-Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees the resources to pursue their goals, both at work and in their personal lives.

We are seeking a Scientist I with hands-on experience in antibody discovery using hybridoma or B-cell approaches to support therapeutic biologics programs and reagent antibody generation in the Biologics Lead Discovery group.  Responsibilities will include designing immunization and screening strategies and developing and executing antibody characterization assays including binding and functional assays.  The candidate must have in-depth knowledge of current antibody generation technologies and be able to apply this to practice at the bench. A strong background in cell culture is required and experience with B-cell selection and growth is a plus. The position will be responsible for executing on multiple projects and representing the Biologics Lead Discovery function on project teams.

Requirements


• PhD in cell biology, immunology, or related field with 2+ years experience/ Bachelor’s or Master’s degree with 5 + years experience
• Previous experience in antibody discovery using hybridoma or B-cell approaches employing immunization approaches.
• Experience with antibody binding assays including ELISA, HTRF, high throughput and multiparameter flow cytometry, and SPR (Octet, Biacore).
• Organized and detail-oriented.
• Ability to manage multiple projects.
• Strong written and verbal communication skills.
• Experience with B-cell selection/sorting and activation and antibody sequencing is a plus.
• Experience with next-gen sequencing approaches is a plus.

Bristol-Myers Squibb is an equal opportunity employer - Vet/Disability


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Research Investigator - Translational Immuno-Oncology

Date Posted:
2/19/2017

Bristol Myers Squibb

NJ

Bristol-Myers Squibb is a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases.

One shared journey is moving us forward at Bristol-Myers Squibb. Around the world, we are passionate about making an impact on the lives of patients with serious disease. Empowered to apply our individual talents and ideas so that we can learn and grow together. And driven to make a difference, from innovative research to hands-on community support. Bristol-Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees the resources to pursue their goals, both at work and in their personal lives.

The successful candidate will be responsible for performing innovative translational research in immunology and immuno-oncology. This includes designing and conducting molecular and cell based assays to dissect the molecular pathology of disease and assist in the development of human target engagement and pharmacodynamic assays. Additionally, the candidate will be involved in laboratory work aimed at generating data to support hypotheses for patient stratification and disease indication selection across autoimmune diseases and cancers for clinical and preclinical drug development candidates. The position requires experience with human immunological assays and datasets including flow cytometry, genomics and functional assays. Familiarity with bioinformatics tools are a plus, as well as, the ability to integrate large datasets. The position will also require working as a member of a translational team and representing the translational biology group in matrix organization. The candidate should also be able to work independently and have excellent interpersonal communication skills.

Requirements


• Scientist with a Ph.D. in the area of Cellular or Immunological sciences with at least 5 years of post- graduate working experience, with preferably at least 2 years in an industrial setting.
• Familiarity with human translational research in immunology or oncology is preferred.
• Evidence of project leadership with good communication skills and a publication record in peer reviewed journals are considered key qualifications.


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Postdoctoral Fellow

Date Posted:
2/19/2017

New England Biolabs

MA

The DNA Enzymes Division of New England Biolabs invites applicants for the position of Postdoctoral Fellow. Projects will be a part of a research program on reverse transcriptase biochemistry and mechanism of action. The applicant will characterize reverse transcriptases utilizing cutting-edge assays including RNA-seq.

Primary Responsibilities

    • Discovery and characterization of novel enzymes.
    • Publishing novel scientific work in peer-reviewed journals and presenting at scientific conferences.

 

Required Qualifications

    • Recent Ph.D. in biochemistry, molecular biology, genomics or related field.
    • Technical expertise in biochemistry and molecular biology techniques.
    • Effective scientific communication in both formal and informal settings.
    • Proven track record of publications in high-quality journals .

 

Preferred Qualifications

    • Experience with high-throughput NGS sequencing and data analysis.
    • Familiarity with single cell genomics and transcriptomics is a plus.
    • Ability to work independently and as part of a multidisciplinary team.
    • Strong work ethic, emphasizing both efficiency and quality of work.

 

This position offers exciting opportunities for broad research training, collaboration with academic and industrial institutions, publishing in peer-reviewed journals and participation in national and international conferences.

New England Biolabs is an Equal Opportunity/ Affirmative Action Employer of Minorities, Females, Disabled and Protected Veterans


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R&D Postdoctoral Fellows - Multiple

Date Posted:
2/19/2017

Ascent Bio-Nano Technologies

NC

Ascent Bio-Nano Technologies, Inc., is a research spin-off from the Pennsylvania State University formed in 2012. We recently relocated to RTP, NC in 2016. The mission is to develop gentle and safe cell and particle separation research tool and medical device. The company motto is Innovation for Impact. Our passion is to commercialize world leading acoustofluidic technologies to advance research, enhance health and improve life quality.  http://ascentbionano.com/careers/

To learn more about the technology platform, please visit our collaborator’s website https://acoustofluidics.pratt.duke.edu/

Currently, we have the following opportunities open in Research and Development (R&D):
Intern:
Undergraduate students with major in applicable science or engineering curriculum (acoustics, electronics, electromechanical systems, etc.)
Hands on experience of developing microfluidics device or electronics system 

Post-doc: 
PhD with major in applicable science or engineering curriculum (acoustics, electronics, electromechanical systems, etc.)
Relevant research experience of acoustic wave separation, microfluidics device or cell biology
Excellent research publication record

Ultrasonic consultant to full time: see below for requirement
Spacer ImageRequirements for Ultrasonic R&D Consultant. This could become a full time position if works out well.

We invite engineers with passion to make an impact to the world to join us.  The consultant should be a great team player who is comfortable working with start up team. The consultant will assist a team of R&D engineers and researchers in the development of cutting edge electroacoustic devices to commercialization. The duties will include: improve performance and stability of microfluidic acoustic based device, provide guidance on R&D development, design electronic and electromechanical prototypes from lab prototypes, facilitate the development of ready to manufacturer prototype, implement good engineering practices, etc.

Minimum requirements:
• Local candidate resides near RTP, NC
• PhD or Master’s Degree in an applicable science or engineering curriculum (acoustics, electronics, electromechanical systems)
• Five or more years of industrial product development and R&D experience
Only candidates meeting the minimum requirements will be considered for interviews.

A desired candidate will have either some or most of the following experience:
Product Development:
• Extensive R&D experience of medical device, blood transfusion technology or cell therapy industry is highly desired.
• Experience of fabricating acoustic device or microfluidic device
• Electroacoustic devices such as surface acoustic wave generators, ultrasound transducers or other resonators
• Engineering materials, especially those related to high frequency acoustic devices
• Experience with fluidic control, including microfluidics, pumps and flow and pressure regulation
• The design of analog electronic circuits in the RF frequency range including power RF
• Digital control systems, microcontrollers, digital signal processors and sensors

Manufacturing:
• Manufacturing of prototype devices including CNC machining, soft cavity molding, water jet cutting, laser cutting, EDM, etc.
• Process and practice of developing ready to manufacturing prototypes
• Knowledge of large scale manufacturing including injection molding, chemical etching, automated assembly and in-process testing.
• Qualifying and dealing with vendors and suppliers
• Meeting and negotiating with customers
 
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Senior Scientist

Date Posted:
2/19/2017

Invitrox

NC

-PhD in an appropriate area such as Analytical Chemistry, Pharmacology, Medicinal Chemistry or the like, and the completion of a post-doctoral fellowship in a clinical or biological application area is required.

-Experience in the operation and maintenance of mass spectrometry instrumentation and in assay development in the processing of biological samples for mass spectrometry analysis are expected.

-Competency in report writing and oral presentations is highly desirable.

-Must be available to analyze clinical samples on a work-week schedule, 8AM-5PM Monday-Friday and able to work constructively in a team oriented environment.


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Teaching Postdoctoral Fellow

Date Posted:
2/19/2017

NCSU

NC

The Biotechnology Program at North Carolina State University http://biotech.ncsu.edu invites applications for a position as Teaching Postdoctoral Scholar in the area of molecular biology. Responsibilities will include teaching sections at the graduate and undergraduate levels of an existing course that covers manipulation and expression of recombinant DNA, and developing and implementing a new laboratory course in a cutting-edge area of molecular biotechnology in the fellow’s area of expertise. The successful candidate must have strong interpersonal skills and teaching ability. A Ph.D. in molecular biology or a related field is required, and postdoctoral research experience is preferred. This is a 12-month position, and is renewable for up to 3 years, based on performance and funding. The position is available starting in Spring 2017.

For further information or to apply, go to https://jobs.ncsu.edu and search for position number 00105923. Applicants should attach the following materials to their application profile: cover letter, curriculum vitae, contact information for three references and a short statement of teaching philosophy and research interests.

Screening of applications begins immediately and will continue until the position is filled. For questions regarding the position responsibilities, please contact: Dr. Sabrina Robertson at sedought@ncsu.edu.

AA/EOE. NC State University is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, national origin, religion, sex, gender identity, age, sexual orientation, genetic information, status as an individual with a disability, or status as a protected veteran. Individuals with disabilities requiring disability-related accommodations in the application and interview process, please call 919-515-3148. Final candidates are subject to criminal & sex offender background checks. Some vacancies also require credit or motor vehicle checks. If highest degree is from an institution outside of the U.S., final candidates are required to have their degree verified at www.wes.org. Degree must be obtained prior to start date. NC State University participates in E-Verify. Federal law requires all employers to verify the identity and employment eligibility of all persons hired to work in the United States.


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Scientist Structural Biology

Date Posted:
2/19/2017

Dart Neuroscience

CA

DNS is seeking an experienced protein chemist for the structural biology department. The candidate will be responsible for the development and implementation of protein purification processes for macromolecular crystallography studies as well as for biochemical/biophysical assay development and screening. The candidate is also required to have an extensive technical background in state-of-the-art protein purification equipment such as AKTA and processes necessary to establish purification procedures that reproducibly lead to the generation of crystallization-grade protein in quantity and quality suitable for structural studies. Major responsibilities will include independent hands-on experimental protein chemistry work to support large scale protein purification and characterization. Experience in membrane protein chemistry and/or protein crystallography is a plus.

The candidate will be working in a creative, dynamic environment and will be required to be team-oriented with a desire to proactively seek out and implement new technologies to improve construct design, expression, purification and crystallization of proteins for 3D structural studies. The candidate must have excellent interpersonal skills and must be organized and timely with regard to data generation, meeting presentations and study reports.

Requirements


Ph.D. in life science with thesis.
• 2+ years of relevant experience in protein structural biology
• Expert knowledge and hands-on experience in successful expression, purification, bioanalytical and biochemical characterization of proteins originating from different protein families for crystallization and 3D-structure determination.
• Proven hands-on experience in different protein purification methods (e.g affinity, size-exclusion, ion-exchange, isoelectric focusing chromatography, etc.) and biochemical/biophysical characterization techniques (e.g., Western blot, light scattering, calorimetry, analytical ultracentrifugation, DLS, thermal melting, protein MassSpec, in vitro assay development, etc.).
• Proven in-depth knowledge and expertise in protein structural biology demonstrated preferably through principle authorship in peer-reviewed publication(s).
• Demonstrated independent thought/creativity in science. Excellent collaboration, communication (oral and written) and multitasking skills and able to present work formally to Scientific Research Committees.
 

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Scientist 1 Biophysics

Date Posted:
2/19/2017

Medimmune

MD

If you’re inspired by the possibilities of science to change lives and you thrive when making brave decisions – join us.  

   MedImmune is the worldwide biologics research and development arm of AstraZeneca. Here, you’ll have the opportunity to make a difference in people’s lives every day. As one of the world’s premier biotechnology companies, our mission is centered on delivering life-changing products that advance world health, and help fight and cure disease.  As a Scientist I, Biophysics in Gaithersburg, MD, you’ll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients’ lives.  

   We’re constantly pushing the boundaries of science to deliver life-changing medicines to patients, with a passion for discovery and a pipeline to show for it. We’re pioneering innovative research and exploring novel pathways across key therapeutic areas including oncology, respiratory, inflammation and autoimmunity, cardiovascular and metabolic disease, and infection and vaccines. And we’re industry-leading in immunology, protein engineering and translational science. We offer a unique and strong collaborative network as part of the AstraZeneca family, as together we explore synergies between small and large molecules.  

   MedImmune has a dynamic environment that fosters collaboration and innovation. We attract top minds, and we nurture and build top talent.  

   Main Duties and Responsibilities  

   We are seeking a highly motivated scientist to join our analytical sciences group at MedImmune. This is a laboratory-based position primarily responsible for particle, higher order structure (HOS), and biophysical characterization of humanized monoclonal antibodies, antibody-drug conjugates, and recombinant proteins and peptides.  

   Responsibilities will include method development, elucidation of structure, comparability, characterization, and investigations of protein therapeutics and vaccines.  You will be preparing presentations, technical reports, and scientific publications.  You will also work on complex and technically demanding projects where analysis of data requires an evaluation of multiple variables.  

   You will have hands-on competency and theoretical understanding in several of the following technique categories:  

       
  •      spectroscopy (circular dichroism, fluorescence, infrared spectroscopy, RAMAN, NMR)    
  •    
  •      calorimetry (differential scanning calorimetry, isothermal titration calorimetry)    
  •    
  •      protein association analysis (analytical ultracentrifugation, light scattering, chromatography)    
  •    
  •      particle analysis (light obscuration, flow microscopy, FTIR microscopy).    
  •  

Requirements

   Essential Requirements     

  •      PhD and 0-3 years    
  •     or     
  •      MS with 8-10 years    

   or  

       
  •      BS with 10-13 years of relevant experience    
  •  
       
  •      Good communicator and collaborator    
  •    
  •      Able to work in a diverse work environment    
  •    
  •      Good organizational skills    
  •  

   Desirable Requirements:  

       
  •      PhD degree in Biochemistry/Biophysical Chemistry/Biochemical Engineering or similar.    
  •    
  •      Hands-on laboratory experience and knowledge of the theoretical principles in biophysical characterization of proteins.    
  •    
  •      Candidates with industrial or institutional experience in biopharmaceutical research and development or protein chemistry or research are encouraged to apply for this position.    
  •  

   Next Steps – Apply today!    

   To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity.  If you know someone who would be a great fit, please share this posting with them.  

   AstraZeneca is an equal opportunity employer.  AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.  

 


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Senior Scientist and Policy Analyst

Date Posted:
2/19/2017

Friends of Cancer Research

DC

Position Overview:
Friends of Cancer Research is currently seeking a talented and motivated senior scientist to play a lead role in the science policy initiatives and research programs of the organization. Through close coordination with the President & CEO and scientific staff, this individual will have the opportunity to develop original research and implement a range of exciting scientific activities designed to optimize and accelerate cancer research. Interested candidates should have in-depth knowledge regarding the processes associated with pre-market development, regulation, and post-market assessments of new drugs and medical devices.
Friends of Cancer Research drives collaboration among partners from every healthcare sector to power advances in science, policy and regulation that speed life-saving treatments to patients.

Major Duties and Responsibilities:

  • Help engineer and oversee the science-based agenda through conference issue briefs, comprehensive policy white papers, health research studies, congressional testimony, and position statements
  • Be a part of a team of science policy analysts to develop and implement the organization's scientific, regulatory, and policy activities
  • Work with multi-stakeholder advisory committees toward the development of policy whitepapers in conjunction with multiple forums throughout the year
  • Conduct original health policy research studies for publication in peer reviewed journals
  • Assist in the substantive preparation of science-related public presentations
  • Share responsibility for representing the organization at scientific conferences
  • Develop policy recommendations and advocacy strategies for scientific and regulatory affairs
  • Work with Friends leadership to develop and cultivate collaborative relationships that will facilitate the accomplishment of organizational goals and fundraising efforts
  • Recruit and supervise interns
  • Other duties and responsibilities as assigned by the President & CEO, Chairperson, or Board of Directors

Qualifications:

  • Graduate degree required - MD or PhD in science-related field preferred
  • Eight or more years of experience in a regulatory, policy, healthcare and/or biomedical research profession
  • A detailed knowledge of scientific and regulatory processes associated with drug and diagnostic development
  • A thorough understanding of healthcare policy and legislative processes
  • High-quality written and verbal communications skills Experience working collaboratively with professionals from different heath related sectors (government, academia, and/or private industry)
  • Outstanding organizational skills and an ability to handle multiple projects simultaneously
  • The ability to work under pressure and respond quickly to shifts in priorities
  • A self-starter with creativity and initiative
  • A willingness to work in a collaborative, informal office setting

To Apply:
Please submit a cover letter describing your interest in science policy, and specifically this position, as well as a resume or CV tojobs@focr.org with Senior Scientist in the subject line

Friends of Cancer Research does not and shall not discriminate on the basis of race, color, religion (creed), gender, gender expression, age, national origin (ancestry), disability, marital status, sexual orientation, or military status, in any of its activities of operations


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Drug Development Program Manager

Date Posted:
2/19/2017

Global Solutions Network

MD